MycoData

Ophiocordyceps sinensis, a high-altitude medicinal mushroom, is widely revered in traditional medicine for its antiproliferative, antihypercholesterolemic, energy enhancement, etc. properties.

Energy & fatigueMetabolic health

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Turkey Tail · 2020 · Journal Article · Research in veterinary science

Biodegradation of aflatoxin B1 with cell-free extracts of Trametes versicolor and Bacillus subtilis.

Aflatoxin B1 (AFB1) is one of the most common contaminants of poultry feed and has been linked to adverse effects on animal health and productivity. In this study, the degradation of AFB1 was studied with cell-free extracts (CFE) of Trametes versicolor and Bacillus subtilis using High-Performance Liquid chromatography….

Energy & fatigue

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Chaga · 2020 · Research Article · ACS omega

Cecal Butyrate (Not Propionate) Was Connected with Metabolism-Related Chemicals of Mice, Based on the Different Effects of the Two Inonotus obliquus Extracts on Obesity and Their Mechanisms.

Obesity is a metabolic disease and causes significant changes in host and gut microbial metabolite levels. However, little research has been done on the relationship between host and gut microbial metabolites..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

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Lion's Mane · 2020 · Journal Article · International journal of biological macromolecules

Characterization of polysaccharides isolated from Hericium erinaceus and their protective effects on the DON-induced oxidative stress.

In this study, the structure characteristic of the Hericium erinaceus polysaccharide (HEP) was investigated using Fourier transformed infrared spectrometry (FT-IR), gas chromatography-mass spectrometry (GC-MS), gel permeation chromatography (GPC), methylation and nuclear magnetic resonance (NMR)..

OncologyImmune supportEnergy & fatigueMetabolic health

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Cordyceps · 2020 · Research Article · PeerJ

Comparative transcriptome analysis revealed genes involved in the fruiting body development of Ophiocordyceps sinensis.

Ophiocordyceps sinensis is a highly valued fungus that has been used as traditional Asian medicine. This fungus is one of the most important sources of income for the nomadic populations of the Tibetan Plateau.

Energy & fatigue

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Snow Fungus · 2020 · Journal Article · International journal of biological macromolecules

Degradation of Tremella fuciformis polysaccharide by a combined ultrasound and hydrogen peroxide treatment: Process parameters, structural characteristics, and antioxidant activities.

The degradation effect of ultrasound (US)/hydrogen peroxide (H2O2) on Tremella fuciformis polysaccharide (TFP) were studied. The main process parameters of degradation were evaluated and the structural changes and antioxidant activities of TFP before and after US/H2O2 were analyzed..

Immune supportEnergy & fatigue

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Enoki · 2020 · Research Article · Journal of animal science and biotechnology

Determination of the available energy values and amino acid digestibility of Flammulina velutipes stem waste and its effects on carcass trait and meat quality fed to growing-finishing pigs.

BACKGROUND: Flammulina velutipes stem waste (FVS) is the by-product of mushroom industry. The objectives of this study were to determine the available energy and amino acid digestibility of FVS fed to pigs, and to evaluate the effects of dietary FVS inclusion on growth performance, biochemical profile of serum, fecal….

Cognition & nervesEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Yellow Morel · 2020 · Journal Article · International journal of medicinal mushrooms

Dichloromethane Extract of Fermentation Broth by Co-Culture of Morchella esculenta and Coprinus comatus Induces Apoptosis in U251 Cells via Mitochondrial Intrinsic Pathway.

The current study was designed to investigate the inhibitory effects of dichloromethane extract of fermentation broth by co-culture of Morchella esculenta and Coprinus comatus (DCMM) on human glioma U251 cells in vitro and its possible underlying mechanisms..

OncologyEnergy & fatigue

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Oyster Mushroom · 2020 · Journal Article · Journal of the science of food and agriculture

Effect of cultivating Pleurotus ostreatus on substrates supplemented with herb residues on yield characteristics, substrates degradation, and fruiting bodies' properties.

BACKGROUND: Inappropriate disposal of herb residues in China has caused major problems for the immediate environment and to human safety. Here, three herb residues, compound Kushen injection (CKI), Qizhi Tongluo capsule (QTC), and Shenbai Shuxin capsule (SSC), were applied as substrates to corncob at various ratios….

Immune supportEnergy & fatigue

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Turkey Tail · 2020 · Journal Article · Chemosphere

Exploring the degradation capability of Trametes versicolor on selected hydrophobic pesticides through setting sights simultaneously on culture broth and biological matrix.

Pesticides introduced inadvertently or deliberately into environment by global agricultural practices have caused growing public concern, therefore the search of approaches for elimination of such xenobiotics should be motivated..

Energy & fatigue

High relevance

Lion's Mane · 2020 · Research Article · International journal of molecular sciences

Hericium Erinaceus Prevents DEHP-Induced Mitochondrial Dysfunction and Apoptosis in PC12 Cells.

Hericium Erinaceus (HE) is a medicinal plant known to possess anticarcinogenic, antibiotic, and antioxidant activities. It has been shown to have a protective effect against ischemia-injury-induced neuronal cell death in rats..

OncologyCognition & nervesEnergy & fatigueRespiratory

High relevance

Cordyceps · 2020 · Journal Article · Applied microbiology and biotechnology

Identification of the genes involved in growth characters of medicinal fungus Ophiocordyceps sinensis based on Agrobacterium tumefaciens-mediated transformation.

Ophiocordyceps sinensis, one of the well-known and precious fungal species in the world, parasitizes soil-dwelling larvae of ghost moths on the Tibetan Plateau. The genetic intractability of this extremely psychrophilic and slow-growing O.

Energy & fatigueGut & microbiome

High relevance

Chaga · 2020 · Journal Article · International journal of biological macromolecules

Inonotus obliquus polysaccharide ameliorates impaired reproductive function caused by Toxoplasma gondii infection in male mice via regulating Nrf2-PI3K/AKT pathway.

This study was carried out to investigate the effects of Inonotus obliquus polysaccharide (IOP) on impaired reproductive function and its mechanisms in Toxoplasma gondii (T. gondii)-infected male mice..

OncologyImmune supportEnergy & fatigue

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Enoki · 2020 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Multiple fingerprint and fingerprint-activity relationship for quality assessment of polysaccharides from Flammulina velutipes.

Polysaccharides are known as one of the most important bioactive compounds in Flammulina velutipes. However, there is no accurate and comprehensive assessment method to evaluate and authenticate F.

Immune supportEnergy & fatigue

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Enoki · 2020 · Journal Article · Food chemistry

Nanocomposite packaging regulates extracellular ATP and programed cell death in edible mushroom (Flammulina velutipes).

Our previous study indicated that nanocomposite packaging material (Nano-PM) containing nano-Ag, nano-TiO2, nano-SiO2 and nanoattapulgite alleviated postharvest senescence of Flammulina velutipes by regulating respiration and energy metabolism..

Energy & fatigue

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Oyster Mushroom · 2020 · Journal Article · Anais da Academia Brasileira de Ciencias

Nephroprotective effect of Pleurotus ostreatus extract against cadmium chloride toxicity in rats.

Cadmium, present in the environment, accumulates in different organs of animals and humans, and has deleterious effects on the kidney. In this study, we investigated the protective effects of the methanolic extract of Pleurotus ostreatus in comparison with silymarin on renal function in cadmium-intoxicated rats for….

Energy & fatigue

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Lion's Mane · 2020 · Research Article · BMC complementary medicine and therapies

Neuroprotective effects of Hericium erinaceus (Bull.: Fr.) Pers. against high-dose corticosterone-induced oxidative stress in PC-12 cells.

BACKGROUND: Hericium erinaceus is a culinary and medicinal mushroom in Traditional Chinese Medicines. It has numerous pharmacological effects including immunomodulatory, anti-tumour, anti-microbial, anti-aging and stimulation of nerve growth factor (NGF) synthesis, but little is known about its potential role in….

OncologyImmune supportCognition & nervesEnergy & fatigue

High relevance

Lion's Mane · 2020 · Research Article · Foods (Basel, Switzerland)

Optimization of Ultrasonic Extraction to Obtain Erinacine A and Polyphenols with Antioxidant Activity from the Fungal Biomass of Hericium erinaceus.

Hericium erinaceus is a medicinal fungal species that produces the active biological metabolite erinacine A with strong antioxidant activity. The classical extraction techniques used to date to obtain metabolites from this fungal species require high consumption of resources and energy and, in the end, prove to be….

Cognition & nervesEnergy & fatigue

High relevance

Zhu Ling · 2020 · Journal Article · International journal of biological macromolecules

Preparation, physicochemical characterization, and anti-proliferation of selenium nanoparticles stabilized by Polyporus umbellatus polysaccharide.

Selenium nanoparticles (SeNPs), a novel selenium form, have attracted worldwide attention due to their bioactivities and low toxicity. This study aimed to assess the physicochemical characterization, storage stability, and anti-proliferative activities of SeNPs stabilized by Polyporus umbellatus polysaccharide (PUP)..

OncologyImmune supportEnergy & fatigue

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Niu-Chang-Chih · 2020 · Research Article · Nutrients

Protective Effect of Spore Powder of Antrodia camphorata ATCC 200183 on CCl4-Induced Liver Fibrosis in Mice.

Liver fibrosis is a pathological process with intrahepatic diffused deposition of the excess extracellular matrix, which leads to various chronic liver diseases. Drugs with high efficacy and low toxicity for liver fibrosis are still unavailable..

OncologyImmune supportEnergy & fatigueLiver support

High relevance

Maitake · 2020 · Journal Article · International journal of biological macromolecules

Regulatory effect of Grifola frondosa extract rich in polysaccharides and organic acids on glycolipid metabolism and gut microbiota in rats.

The present study investigated the composition of water extract of Grifola frondosa (GFWE) and its regulatory effects on glycolipid metabolism and gut microbiota in rats..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Maitake · 2020 · Journal Article · Journal of food biochemistry

The hypoglycemic and renal protective effects of Grifola frondosa polysaccharides in early diabetic nephropathy

Grifola frondosa is a basidiomycete polypore fungus. Polysaccharides from G.

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Chaga · 2020 · Journal Article · Applied biochemistry and biotechnology

The Influence of Submerged Fermentation of Inonotus obliquus with Control Atmosphere Treatment on Enhancing Bioactive Ingredient Contents.

This study led in the pioneering technique incubated in a bioreactor with the forced air injection system. The purpose of this study was to establish the optimal incubation conditions for this technique..

Energy & fatigue

High relevance

Maitake · 2020 · Journal Article · Glycoconjugate journal

The preparation of a cold-water soluble polysaccharide from Grifola frondosa and its inhibitory effects on MKN-45 cells.

In this study, a novel water soluble polysaccharide (named GFP-4) was extracted from Grifola frondosa at 4 oC, and its preliminary structure and inhibitory effects on human gastric carcinoma MKN-45 cells through the Fas/FasL death receptor apoptosis pathway were investigated..

OncologyImmune supportEnergy & fatigueMetabolic health

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Lion's Mane · 2019 · Journal Article · International journal of biological macromolecules

A polysaccharide from cultured mycelium of Hericium erinaceus relieves ulcerative colitis by counteracting oxidative stress and improving mitochondrial function.

EP-1 is a polysaccharide with a molecular weight of approximately 3100 Da, which is extracted from the cultured mycelium of Hericium erinaceus. Its anti-ulcerative colitis activity was evaluated in experimental systems using rats with ulcerative colitis and Caco-2 cells as models for experimentation..

OncologyImmune supportEnergy & fatigueGut & microbiome

High relevance

Maitake · 2019 · Journal Article · Applied biochemistry and biotechnology

Anti-Diabetic and Anti-Nephritic Activities of Grifola frondosa Mycelium Polysaccharides in Diet-Streptozotocin-Induced Diabetic Rats Via Modulation on Oxidative Stress.

Grifola frondosa is an edible fungus with a variety of potential pharmacological activities. This study investigates the hypoglycemic, anti-diabetic nephritic, and antioxidant properties of G.

Immune supportEnergy & fatigueMetabolic health

High relevance

Yellow Morel · 2019 · Journal Article · International journal of biological macromolecules

Anti-inflammatory effects of Morchella esculenta polysaccharide and its derivatives in fine particulate matter-treated NR8383 cells.

Fine particulate matter (PM2.5) exposure could cause many acute and chronic respiratory diseases. In this study the protective effects of polysaccharide from Morchella esculenta (FMP-1) and its derivatives against PM2.5-induced inflammation were evaluated..

OncologyImmune supportEnergy & fatigueRespiratory

High relevance

Niu-Chang-Chih · 2019 · Research Article · International journal of molecular sciences

Antidiabetic and Antihyperlipidemic Effects of Sulphurenic Acid, a Triterpenoid Compound from Antrodia camphorata, in Streptozotocin-Induced Diabetic Mice.

The present study was designed to evaluate the protective effect of sulphurenic acid (SA), a pure compound from Antrodia camphorata, on diabetes and hyperlipidemia in an animal model study and to clarify the underlying molecular mechanism..

Energy & fatigueMetabolic healthLiver support

High relevance

Turkey Tail · 2019 · Journal Article · Industrial crops and products

Biological pretreatment with Trametes versicolor to enhance methane production from lignocellulosic biomass: a metagenomic approach

The presence of poorly biodegradable components in lignocellulosic biomass limits the methane recovery in anaerobic digesters. The main reason to go for aerobic pretreatment before anaerobic digestion (AD) is to enable enzymatic cleavage of the aromatic rings in lignin by oxygen since it cannot be efficiently degraded….

Energy & fatigueGut & microbiome

High relevance

Enoki · 2019 · Research Article · Antioxidants (Basel, Switzerland)

Characterization and Antioxidant Activities of Yellow Strain Flammulina velutipes (Jinhua Mushroom) Polysaccharides and Their Effects on ROS Content in L929 Cell.

Yellow strain Flammulina velutipes, which is known as Jinhua mushroom in Taiwan, has become popular among customers due to its distinct texture that is utterly different from white strain F. velutipes..

OncologyImmune supportEnergy & fatigueSkin & hydration

High relevance

Cordyceps · 2019 · Research Article · Molecules (Basel, Switzerland)

Characterization of Humic Substances in the Soils of Ophiocordyceps sinensis Habitats in the Sejila Mountain, Tibet: Implication for the Food Source of Thitarodes Larvae.

Humic substances in soil are considered to be an alternative food to the tender plant roots for Thitarodes larvae in the habitats of Ophiocordyceps sinensis in the Qinghai-Tibetan Plateau..

Energy & fatigue

High relevance

Cordyceps · 2019 · Journal Article · International journal of biological macromolecules

Complete mitochondrial genome of two Thitarodes species (Lepidoptera, Hepialidae), the host moths of Ophiocordyceps sinensis and phylogenetic implications.

Thitarodes (Lepidoptera, Hepialidae) is the only genus that hosts to the Ophiocordyceps sinensis, a traditional Chinese medicine considered as a powerful medicinal supplement. In this study, the complete mitochondrial genomes (mitogenomes) of two species, T.

Energy & fatigue

High relevance

Turkey Tail · 2019 · Journal Article · Chemosphere

Cu2+-assisted laccase from Trametes versicolor enhanced self-polyreaction of triclosan.

Laccase-mediated humification processes (L-MHPs) can be used to polymerize and transform phenolic pollutants in water. However, the mechanism on Cu2+ impacts the self-polymerization of multi-purpose antimicrobial agent triclosan during L-MHPs is less understood..

Energy & fatigue

High relevance

Enoki · 2019 · Journal Article · Journal of the science of food and agriculture

Dietary inclusion of mushroom (Flammulina velutipes) stem waste on growth performance and immune responses in growing layer hens

BACKGROUND: Medicinal mushrooms contain biologically active substances that can be used as an immune‐modulating agent in poultry. The present study aimed to investigate the effects of Flammulina velutipes mushroom waste (FVW) on performance, immune response and serum immunity in growing layer hens..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Enoki · 2019 · Journal Article · Journal of the science of food and agriculture

Dietary inclusion of mushroom (Flammulina velutipes) stem waste on growth performance and immune responses in growing layer hens.

BACKGROUND: Medicinal mushrooms contain biologically active substances that can be used as an immune-modulating agent in poultry. The present study aimed to investigate the effects of Flammulina velutipes mushroom waste (FVW) on performance, immune response and serum immunity in growing layer hens..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Enoki · 2019 · Research Article · Animals: an open access journal from MDPI

Dietary Inclusion of Mushroom (Flammulina velutipes) Stem Waste on Growth Performance, Antibody Response, Immune Status, and Serum Cholesterol in Broiler Chickens.

This study was carried out to investigate the effects of mushroom (Flammulina velutipes) stem waste (MW) on growth performance, antibody response, immune status, and serum cholesterol in broiler chickens..

Immune supportEnergy & fatigueMetabolic health

High relevance

Turkey Tail · 2019 · Research Article · ACS omega

Effect of Template Type on the Trametes versicolor Laccase-Catalyzed Oligomerization of the Aniline Dimer p-Aminodiphenylamine (PADPA).

Many previous studies have shown that (i) the oxidation of aniline or the aniline dimer p-aminodiphenylamine (PADPA) in a slightly acidic aqueous solution can be catalyzed with heme peroxidases or multicopper laccases and that (ii) subsequent reactions lead to oligomeric or polymeric products, which resemble….

Energy & fatigue

High relevance

Turkey Tail · 2019 · Journal Article · Journal of cosmetic dermatology

Enzymatic hydrolysates obtained from Trametes versicolor polysaccharopeptides protect human skin keratinocyte against AAPH-induced oxidative stress and inflammatory.

BACKGROUND: Polysaccharopeptides (PSPs) extracted from Trametes versicolor show antitumor, anti-inflammatory, and immunomodulation effects. According to our previous report, the enzymatic hydrolysates obtained from T versicolor PSPs by 80 U/mL β-1,3-D-glucanase (PSPs-EH80) did not change the functional groups of PSPs….

OncologyImmune supportEnergy & fatigueSkin & hydration

High relevance

Shiitake · 2019 · Research Article · International journal of molecular sciences

GC⁻MS-Based Nontargeted and Targeted Metabolic Profiling Identifies Changes in the Lentinula edodes Mycelial Metabolome under High-Temperature Stress.

To clarify the physiological mechanism of the Lentinula edodes (L. edodes) response to high-temperature stress, two strains of L.

Energy & fatigueMetabolic health

High relevance

Yellow Morel · 2019 · Research Article · Oxidative medicine and cellular longevity

Hepatoprotective Effects of Morchella esculenta against Alcohol-Induced Acute Liver Injury in the C57BL/6 Mouse Related to Nrf-2 and NF-κB Signaling.

This study investigated the hepatoprotective effects of Morchella esculenta fruit body (ME) and the underlying mechanisms in mice with alcohol-induced acute liver injury. Systematic analysis revealed that ME contained 21 types of fatty acid, 17 types of amino acid, and 12 types of mineral..

Immune supportEnergy & fatigueMetabolic healthLiver support

High relevance

Lion's Mane · 2019 · Research Article · Nutrients

Hericium erinaceus Improves Recognition Memory and Induces Hippocampal and Cerebellar Neurogenesis in Frail Mice during Aging.

Frailty is a geriatric syndrome associated with both locomotor and cognitive decline, implicated in both poor quality of life and negative health outcomes. One central question surrounding frailty is whether phenotypic frailty is associated with the cognitive impairment during aging..

Immune supportCognition & nervesEnergy & fatigue

High relevance

Enoki · 2019 · Research Article · Mycobiology

Identification and Characterization of Two New S-Adenosylmethionine-Dependent Methyltransferase Encoding Genes Suggested Their Involvement in Stipe Elongation of Flammulina velutipes.

Two new SAM-dependent methyltransferase encoding genes (fvsmt1 and fvsmt2) were identified from the genome of Flammulina velutipes. In order to make a comprehensive characterization of both genes, we performed in silico analysis of both genes and used qRT-PCR to reveal their expression patterns during the development….

Energy & fatigue

High relevance

Chaga · 2019 · Journal Article · International journal of biological macromolecules

Inonotus obliquus polysaccharides protect against Alzheimer's disease by regulating Nrf2 signaling and exerting antioxidative and antiapoptotic effects.

Inonotus obliquus polysaccharide (IOPS) was initially separated and purified via precipitation from an aqueous extract with 80% alcohol, a DEAE-52 cellulose anion exchange column, and a Sephadex G-100 gel permeation chromatography system. IOPS was found to have a molecular weight of 111.9 kDa..

OncologyImmune supportCognition & nervesEnergy & fatigue

High relevance

Lion's Mane · 2019 · Journal Article · Carbohydrate polymers

Magnetic chitin hydrogels prepared from Hericium erinaceus residues with tunable characteristics: A novel biosorbent for Cu2+ removal.

Development of sustainable biomaterials from wasted resources has been widely advocated recently. In this study, chitin was extracted from Hericium erinaceus residues and used as the main framework to in situ synthesize series of magnetic chitin hydrogels for Cu2+ removal..

Energy & fatigue

High relevance

Maitake · 2019 · Journal Article · Mycoscience

Mitochondrial DNA dynamics during fruiting body formation in Grifola frondosa

In the present study, the copy number of mitochondrial DNA in Grifola frondosa was estimated at several developmental stages by quantitative real-time PCR, revealing that it decreases gradually during fruiting body development..

Energy & fatigueRespiratory

High relevance

Shiitake · 2019 · Journal Article · Journal of agricultural and food chemistry

Remediation and Mechanisms of Cadmium Biosorption by a Cadmium-Binding Protein from Lentinula edodes.

Cadmium bioremediation with metal-binding proteins is primarily conducted using metallothioneins (MTs). However, in the present study, we investigated a non-MT cadmium-binding protein from Lentinula edodes (LECBP) as a remediation tool for cadmium biosorption in Escherichia coli..

Energy & fatigue

High relevance

Shiitake · 2019 · Journal Article · Meat science

Roles of Lentinula edodes as the pork lean meat replacer in production of the sausage.

The effects of substituting pork lean meat with Lentinula edodes (LE) on the physicochemical properties, amino acid content, cooking loss, texture, total phenolic content, antioxidant activity, microstructure, microbiological analysis, and sensory characteristics of sausages were evaluated..

Energy & fatigue

High relevance

Niu-Chang-Chih · 2019 · Research Article · Molecules (Basel, Switzerland)

The Effects of Ergosta-7,9(11),22-trien-3β-ol from Antrodia camphorata on the Biochemical Profile and Exercise Performance of Mice.

Antrodia camphorata (AC) is a rare and unique mushroom that is difficult to cultivate. Previous studies have demonstrated the bioactivity of the compound Ergosta-7,9(11),22-trien-3β-ol (EK100) from AC in submerged culture..

OncologyEnergy & fatigueMetabolic healthLiver support

High relevance

Lion's Mane · 2019 · Research Article · International journal of molecular sciences

The Neuroprotective Effect of Hericium erinaceus Extracts in Mouse Hippocampus after Pilocarpine-Induced Status Epilepticus.

Hericium erinaceus (HE), a culinary-medicinal mushroom, has shown therapeutic potential in many brain diseases. However, the role of HE in status epilepticus (SE)-mediated neuronal death and its underlying mechanisms remain unclear..

Immune supportCognition & nervesEnergy & fatigue

High relevance

Chaga · 2019 · Journal Article · International journal of biological macromolecules

The polysaccharide from Inonotus obliquus protects mice from Toxoplasma gondii-induced liver injury.

The study aimed to explore the protective effects and mechanism of Inonotus obliquus polysaccharide (IOP) on liver injury caused by Toxoplasma gondii (T. gondii) infection in mice..

OncologyImmune supportEnergy & fatigueLiver support