MycoData

Niu-Chang-Chih · 2018 · Research Article · RSC advances

Antidiabetic and hypolipidemic activities of eburicoic acid, a triterpenoid compound from Antrodia camphorata, by regulation of Akt phosphorylation, gluconeogenesis, and PPARα in streptozotocin-induced diabetic mice.

The study is designed to examine the potential effects and underlying mechanisms of eburicoic acid (TRR), a compound from Antrodia camphorata, in streptozotocin (STZ)-induced diabetic mice..

OncologyImmune supportEnergy & fatigueRespiratory

Enoki · 2018 · Research Article · Asian-Australasian journal of animal sciences

Effect of golden needle mushroom (Flammulina velutipes) stem waste on laying performance, calcium utilization, immune response and serum immunity at early phase of production.

OBJECTIVE: This experiment was conducted to evaluate the effects of golden needle mushroom (Flammulina velutipes) stem waste (FVW), on organic eggs production, calcium utilization, antibody response, serum immunoglobulin, and serum cytokine concentration at early phase of production in laying hens..

OncologyEnergy & fatigueMetabolic health

Niu-Chang-Chih · 2018 · Research Article · The Journal of veterinary medical science

Effects of Antrodia camphorata and Panax ginseng supplementation on anti-fatigue properties in mice

Antrodia camphorata and Panax ginseng are well-known medicinal plants in Taiwan folk and traditional Chinese medicine, which have been reported for multifunctional bioactivities..

Immune supportEnergy & fatigueMetabolic healthLiver support

Chaga · 2018 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Effects of polysaccharides from Inonotus obliquus and its chromium (III) complex on advanced glycation end-products formation, α-amylase, α-glucosidase activity and H2O2-induced oxidative damage in hepatic L02 cells.

In the present study, the antioxidant activity, anti-glycation activity, α-amylase, α-glucosidase inhibitory activity of polysaccharides from Inonotus obliquus (UIOPS) and its chromium (III) complex (UIOPC) were investigated..

OncologyImmune supportEnergy & fatigueMetabolic health

Maitake · 2018 · Journal Article · Journal of food science

Enzymatic Modification of Rice Bran Polysaccharides by Enzymes from Grifola Frondosa: Natural Killer Cell Cytotoxicity and Antioxidant Activity.

UNLABELLED: Rice bran polysaccharides (RBPSs) are the major active constituents of rice bran (RB). In this study, we utilized intracellular enzymes from Grifola frondosa to modify RBPSs, which were extracted from RB using ultrasound..

OncologyImmune supportCognition & nervesEnergy & fatigue

Lion's Mane · 2018 · Research Article · International journal of molecular sciences

Erinacine A-Enriched Hericium erinaceus Mycelium Produces Antidepressant-Like Effects through Modulating BDNF/PI3K/Akt/GSK-3β Signaling in Mice.

Antidepressant-like effects of ethanolic extract of Hericium erinaceus (HE) mycelium enriched in erinacine A on depressive mice challenged by repeated restraint stress (RS) were examined. HE at 100, 200 or 400 mg/kg body weight/day was orally given to mice for four weeks..

Energy & fatigueMetabolic health

Turkey Tail · 2018 · Journal Article · Ecotoxicology and environmental safety

Evaluation of a mixed simultaneous vinasse degradation treatment using Komagataeibacter kakiaceti GM5 and Trametes versicolor DSM 3086.

In the bioethanol industry and its derivative processes, 9-14 l of vinasse per liter of ethanol are obtained as residue, depending on whether or not a recirculation process is used..

Immune supportCognition & nervesEnergy & fatigueGut & microbiome

Enoki · 2018 · Journal Article · Food & function

Flammulina velutipes polysaccharides improve scopolamine-induced learning and memory impairment in mice by modulating gut microbiota composition.

Flammulina velutipes polysaccharides (FVP) have been proved to be effective in improving learning and memory impairment in mice. However, their underlying mechanism remains unclear.

Lion's Mane · 2018 · Journal Article · Gene

Proteome analysis provides insight into the regulation of bioactive metabolites in Hericium erinaceus.

BACKGROUND: Hericium erinaceus, a famous edible mushroom, is also a well-known traditional medicinal fungus. To date, a large number of bioactive metabolites with antitumor, antibacterial, and immune-boosting effects were isolated from the free-living mycelium and fruiting body of H.

Maitake · 2018 · Journal Article · International journal of biological macromolecules

Purification, characterization and immunomodulatory activity of a novel polysaccharide from Grifola frondosa.

A novel bioactive polysaccharide, GFP-22, was isolated from the fruit bodies of Grifola frondosa by anion-exchange and gel filtration chromatography. Structure of GFP-22 was investigated using gas chromatography-mass spectrometry (GC-MS), methylation, nuclear magnetic resonance (NMR), high-performance size exclusion….

Yellow Morel · 2018 · Journal Article · Microbial pathogenesis

Total flavones of fermentation broth by co-culture of Coprinus comatus and Morchella esculenta induces an anti-inflammatory effect on LPS-stimulated RAW264.7 macrophages cells via the MAPK signaling pathway.

The inflammatory cellular model of RAW264.7 cells induced by lipopolysaccharide (LPS) has always been used to investigate the effect of anti-inflammatory agents in vitro..

Snow Fungus · 2018 · Research Article · Analytical cellular pathology (Amsterdam)

Tremella fuciformis Polysaccharides Attenuate Oxidative Stress and Inflammation in Macrophages through miR-155.

AIM: To investigate the function of Tremella fuciformis polysaccharides (TFPS) in LPS-induced inflammation and oxidative stress of macrophages. METHODS: RAW264.7 cells were pretreated with TFPS and then stimulated with 0.1 μg/ml LPS.

Lion's Mane · 2017 · Research Article · PloS one

A unique polysaccharide purified from Hericium erinaceus mycelium prevents oxidative stress induced by H2O2 in human gastric mucosa epithelium cell.

Hericium erinaceus (HE) has been used both as a traditional Chinese medicine and home remedy for treatment of gastric and duodenal ulcers and gastritis. EP-1, a purified polysaccharide isolated from HE mycelium, has recently been identified as the active component responsible for HE anti-gastritis activity..

Immune supportEnergy & fatigueLiver support

Maitake · 2017 · Journal Article · International journal of medicinal mushrooms

Anti-Inflammation and Lipogenic Inhibition of Taiwanofungus salmonea Mycelium and Grifola frondosa Fruiting Body.

A long-term inflammatory response can cause the development of nonalcoholic steatohepatitis (NASH), which is mainly caused by abnormal metabolism of lipids in the liver..

Shiitake · 2017 · Research Article · The plant pathology journal

Defense Response and Suppression of Phytophthora Blight Disease of Pepper by Water Extract from Spent Mushroom Substrate of Lentinula edodes.

The spent mushroom substrate (SMS) of Lentinula edodes that was derived from sawdust bag cultivation was used as materials for controlling Phytophthora blight disease of pepper. Water extract from SMS (WESMS) of L..

Turkey Tail · 2017 · Journal Article · Fungal biology

Differential gene expression profiling analysis in Pleurotus ostreatus during interspecific antagonistic interactions with Dichomitus squalens and Trametes versicolor.

This study provided analysis of differentially expressed genes (DEGs) in Pleurotus ostreatus under the interaction with Dichomitus squalens and Trametes versicolor, which is valuable for exploration on the fungal defence system against stressful condition caused by interspecific antagonistic interaction..

Cognition & nervesEnergy & fatigueRespiratory

Lion's Mane · 2017 · Research Article · Frontiers in pharmacology

Docking Studies and Biological Evaluation of a Potential β-Secretase Inhibitor of 3-Hydroxyhericenone F from Hericium erinaceus.

Alzheimer's disease (AD) is the most common neurodegenerative disorder, affecting approximately more than 5% of the population worldwide over the age 65, annually. The incidence of AD is expected to be higher in the next 10 years..

Niu-Chang-Chih · 2017 · Research Article · International journal of molecular sciences

Eburicoic Acid, a Triterpenoid Compound from Antrodia camphorata, Displays Antidiabetic and Antihyperlipidemic Effects in Palmitate-Treated C2C12 Myotubes and in High-Fat Diet-Fed Mice.

This study was designed to investigate the antidiabetic and antihyperlipidemic effects and mechanisms of eburicoic acid (TRR); one component of Antrodia camphorata in vitro and in an animal model for 14 weeks..

Niu-Chang-Chih · 2017 · Journal Article · Journal of the science of food and agriculture

Induction of antroquinonol production by addition of hydrogen peroxide in the fermentation of Antrodia camphorata S-29.

BACKGROUND: Antroquinonol have significantly anti-tumour effects on various cancer cells. There is still lack of reports on regulation of environmental factors on antroquinonol production by Antrodia camphorata.

Niu-Chang-Chih · 2017 · Journal Article · Journal of the science of food and agriculture

Induction of antroquinonol production by addition of hydrogen peroxide in the fermentation of Antrodia camphorata S‐29

BACKGROUND: Antroquinonol have significantly anti‐tumour effects on various cancer cells. There is still lack of reports on regulation of environmental factors on antroquinonol production by Antrodia camphorata.

Chaga · 2017 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Inonotus obliquus extract induces apoptosis in the human colorectal carcinoma's HCT-116 cell line.

Because of irregular dietary habits and lifestyle in Taiwan, the incidence and mortality rate of colorectal cancer have been increasing rapidly these years. This study investigated the inhibitory activity against the proliferation of human colorectal cancer HCT-116 cells by Inonotus obliquus extracts obtained from….

Energy & fatigueMetabolic health

Turkey Tail · 2017 · Journal Article · Applied biochemistry and biotechnology

Pretreatment of Hardwood and Miscanthus with Trametes versicolor for Bioenergy Conversion and Densification Strategies.

The pretreatment of plant biomass negatively impacts the economics of many bioenergy and bioproduct processes due to the thermochemical requirements for deconstruction of lignocelluluose..

Energy & fatigueMetabolic health

Enoki · 2017 · Journal Article · Journal of agricultural and food chemistry

Proteomic Investigation of Metabolic Changes of Mushroom (Flammulina velutipes) Packaged with Nanocomposite Material during Cold Storage.

Metabolic changes of mushroom (Flammulina velutipes) applied with polyethylene (PE) material (Normal-PM) or nanocomposite reinforced PE packaging material (Nano-PM) were monitored using tandem mass tags (TMT) labeling combined with two-dimensional liquid chromatography-tandem mass spectrometry (2D LC-MS/MS) technique..

Turkey Tail · 2017 · Research Article · Bioprocess and biosystems engineering

Simultaneous production of laccase and degradation of bisphenol A with Trametes versicolor cultivated on agricultural wastes.

Solid state fermentation with Trametes versicolor was carried out on agricultural wastes containing bisphenol A (BPA). It was found that BPA degradation was along with the occurrence of laccase production, and wheat bran and corn straw were identified as suitable mixed substrates for laccase production..

Enoki · 2017 · Journal Article · International journal of medicinal mushrooms

Structural Characteristics of the Novel Polysaccharide FVPA1 from Winter Culinary-Medicinal Mushroom, Flammulina velutipes (Agaricomycetes), Capable of Enhancing Natural Killer Cell Activity against K562 Tumor Cells.

FVPA1, a novel polysaccharide, has been isolated from fruiting bodies of the culinary-medicinal mushroom Flammulina velutipes, a historically popular, widely cultivated and consumed functional food with an attractive taste, beneficial nutraceutical properties such as antitumor and immunomodulatory effects, and a….

Shiitake · 2017 · Research Article · Mitochondrial DNA. Part B, Resources

The complete mitochondrial genome of the widely cultivated edible fungus Lentinula edodes.

The complete mitochondrial genome of the widely cultivated edible fungus Lentinula edodes was determined using the next-generation sequencing technology. The circular molecule is 116,819 bp in length with a GC content of 30.75%..

Shiitake · 2016 · Journal Article · International immunopharmacology

Activation of the NRF2-ARE signalling pathway by the Lentinula edodes polysaccharose LNT alleviates ROS-mediated cisplatin nephrotoxicity.

The nephrotoxicity of cisplatin (cis-DDP) limits its general clinical applications. Lentinan (LNT), a dextran extracted from the mushroom Lentinula edodes, has been shown to have multiple pharmacological activities..

Almond Mushroom · 2016 · Journal Article · International journal of oncology

Agarol, an ergosterol derivative from Agaricus blazei, induces caspase-independent apoptosis in human cancer cells.

Agaricus blazei (A. blazei) is a mushroom with many biological effects and active ingredients.

Niu-Chang-Chih · 2016 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Antcin K, a Triterpenoid Compound from Antrodia camphorata, Displays Antidiabetic and Antihyperlipidemic Effects via Glucose Transporter 4 and AMP-Activated Protein Kinase Phosphorylation in Muscles.

The purpose of this study was to screen firstly the potential effects of antcin K (AnK), the main constituent of the fruiting body of Antrodia camphorata, in vitro and further evaluate the activities and mechanisms in high-fat-diet- (HFD-) induced mice..

Maitake · 2016 · Journal Article · International journal of food science & technology

Antioxidant and antitumour activities of exopolysaccharide from liquid‐cultured Grifola frondosa by chemical modification

Grifola frondosa is a popular edible mushroom for its tasty flavour and can be used as a dietary supplement for its functional substances. In this study, an exopolysaccharide (EPS), purified from the submerged culture of G..

Niu-Chang-Chih · 2016 · Research Article · International journal of molecular sciences

Dehydroeburicoic Acid from Antrodia camphorata Prevents the Diabetic and Dyslipidemic State via Modulation of Glucose Transporter 4, Peroxisome Proliferator-Activated Receptor α Expression and AMP-Activated Protein Kinase Phosphorylation in High-Fat-Fed Mice.

This study investigated the potential effects of dehydroeburicoic acid (TT), a triterpenoid compound from Antrodia camphorata, in vitro and examined the effects and mechanisms of TT on glucose and lipid homeostasis in high-fat-diet (HFD)-fed mice..

Enoki · 2016 · Journal Article · Carbohydrate polymers

Development, physiochemical characterization and forming mechanism of Flammulina velutipes polysaccharide-based edible films.

Edible films of Flammulina velutipes polysaccharide were prepared and characterized in terms of rheological, optical, morphologic, mechanical and barrier properties to evaluate their potential application in food packaging..

Almond Mushroom · 2016 · Research Article · PloS one

Effect of the Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSanTM, on Symptoms, Fatigue and Quality of Life in Patients with Crohn's Disease in a Randomized Single-Blinded Placebo Controlled Study.

BACKGROUND: Ingestion of AndoSanTM, based on the mushroom Agaricus blazei Murill, has previously shown an anti-inflammatory effect through reduction of pro-inflammatory cytokines in healthy individuals and patients with Crohn's disease (CD)..

OncologyImmune supportEnergy & fatigueMetabolic health

Chaga · 2016 · Journal Article · Molecular medicine reports

Effects of polysaccharides isolated from Inonotus obliquus against hydrogen peroxide-induced oxidative damage in RINm5F pancreatic β-cells.

The purpose of the present study was to elucidate the cytoprotective effects of polysaccharides isolated from Inonotus obliquus. The polysaccharides were extracted from the fruiting body of I.

Turkey Tail · 2016 · Research Article · Molecules (Basel, Switzerland)

Enhancing the Antioxidant Ability of Trametes versicolor Polysaccharopeptides by an Enzymatic Hydrolysis Process.

Polysaccharopeptides (PSPs) are among the main bioactive constituents of Trametes versicolor (T. versicolor).

OncologyImmune supportCognition & nervesEnergy & fatigue

Lion's Mane · 2016 · Research Article · BMC complementary and alternative medicine

High molecular weight of polysaccharides from Hericium erinaceus against amyloid beta-induced neurotoxicity.

BACKGROUND: Hericium erinaceus (HE) is a well-known mushroom in traditional Chinese food and medicine. HE extracts from the fruiting body and mycelia not only exhibit immunomodulatory, antimutagenic and antitumor activity but also have neuroprotective properties..

Maitake · 2016 · Journal Article · Protein expression and purification

High-yield fermentation and a novel heat-precipitation purification method for hydrophobin HGFI from Grifola frondosa in Pichia pastoris.

Hydrophobins are proteins produced by filamentous fungi with high natural-surfactant activities and that can self-assemble in interfaces of air-water or solid-water to form amphiphilic membranes..

Energy & fatigueLiver supportSkin & hydration

Niu-Chang-Chih · 2016 · Journal Article · Hepatology research: the official journal of the Japan Society of Hepatology

Identification of antrodin B from Antrodia camphorata as a new anti-hepatofibrotic compound using a rapid cell screening method and biological evaluation.

AIM: Liver fibrosis is the excessive accumulation of extracellular matrix (ECM) resulting from chronic liver diseases. Efficient and well-tolerated drugs for its treatment are urgently needed..

Turkey Tail · 2016 · Journal Article · Bioprocess and biosystems engineering

Scale-up laccase production from Trametes versicolor stimulated by vanillic acid.

An efficient strategy for laccase production in Trametes versicolor cultures was developed using vanillic acid as the inducer. The optimized vanillic acid treatment strategy consisted of exposing 2-day-old mycelia cultures to 80 mg/L vanillic acid..

OncologyImmune supportCognition & nervesEnergy & fatigue

Lion's Mane · 2016 · Research Article · International journal of molecular sciences

The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer's Disease Mouse Model.

Hericium erinaceus, an edible and medicinal mushroom, displays various pharmacological activities in the prevention of dementia in conditions such as Parkinson's and Alzheimer's disease. The present study explored the neuroprotective effects of H..

King Oyster · 2005 · Journal Article · Journal of wood science

Cladistic relationships among the Pleurotus ostreatus complex, the Pleurotus pulmonarius complex, and Pleurotus eryngii based on the mitochondrial small subunit ribosomal DNA sequence analysis

The cladistic analysis of the V4 domain sequences, performed by UPGMA, the neighbor-joining, and parsimony methods, revealed that the 19 Pleurotus strains tested in this study evolved along three lineages, each corresponding to a separate biological species: the Pleurotus ostreatus complex, the Pleurotus pulmonarius….

Maitake · 2004 · Research Article · Journal of Tianjin Normal University(Natural Science Edition)

Effect of different pH an protein peptone on mycelial growth rate of Grifola frondosa(Fr.)S.F. Gray

Microelectrode techniques were used to assess the importance of subthreshold electrotonic interactions between the canine proximal bundle branches and adjacent septal myocardium, and vice versa..

Yellow Morel · 2001 · Journal Article · Journal of chromatography. A

Counter-current chromatographic separation of glycoprotein components from Morchella esculenta (L.) with a polymer phase system by a cross-axis coil planet centrifuge.

Using a cross-axis coil planet centrifuge, glycoproteins were separated from fermentation media of Morchella esculenta (L.) by high-speed counter-current chromatography..

Zhu Ling · 1996 · Journal Article · Zhongguo Gonggong Weisheng Xuebao

Preventive study of Polyporus umbellatus Fr. on genetic damage induced by cadmium

The maternal extended family of a young man shown to suffer from periodic paralysis were investigated. Several members were found to have biochemical and symptomatic evidence of muscle disorder..

Cordyceps · 2026 · Journal Article · Scientific data

A chromosome-scale nuclear genome and complete mitogenome of the bio-control fungus Cordyceps cateniannulata.

Cordyceps cateniannulata, a recently characterized entomopathogenic fungus, has been employed in biological control, plant disease management, and growth promotion. In this study, the complete genomic sequences of C.

Cognition & nervesEnergy & fatigue

Shiitake · 2026 · Journal Article · Food Research International

Based on the umami-transformer machine learning model: Screening of umami peptides from ultrasound-assisted enzymatic hydrolysis of shiitake mushrooms and study on their flavor mechanism

This study aimed to optimize ultrasound-assisted enzymatic hydrolysis for umami peptide preparation from shiitake mushrooms, develop a reliable predictive screening model for umami peptides, and clarify the molecular mechanism underlying the umami taste of these peptides..

Cognition & nervesEnergy & fatigue

Shiitake · 2026 · Journal Article · Food research international (Ottawa, Ont.)

Based on the umami-transformer machine learning model: Screening of umami peptides from ultrasound-assisted enzymatic hydrolysis of shiitake mushrooms and study on their flavor mechanism.

Cordyceps · 2026 · Research Article · International journal of medical sciences

Evaluation of the Impact of Cordyceps cicadae Mycelium on Vision Health: A Cohort Study.

Cordyceps cicadae is a traditional Chinese medicinal fungus known for its diverse bioactive compounds and pharmacological properties similar to those of Cordyceps sinensis. Extracts of C..