MycoData

Immune supportMetabolic healthGut & microbiome

Enoki · 2019 · Journal Article · International journal of food science & technology

Characteristic of polysaccharides from Flammulina velutipes in vitro digestion under salivary, simulated gastric and small intestinal conditions and fermentation by human gut microbiota

In this study, in vitro digestion and fermentation of Flammulina velutipes ‐derived polysaccharides (FVP) were investigated. It was found that FVP mainly consisted of 48.45% glucose, 15.40% mannose, 14.60% xylose, 11.80% fucose and 9.90% galactose..

OncologyImmune supportEnergy & fatigueMetabolic health

Enoki · 2019 · Journal Article · Journal of the science of food and agriculture

Dietary inclusion of mushroom (Flammulina velutipes) stem waste on growth performance and immune responses in growing layer hens

BACKGROUND: Medicinal mushrooms contain biologically active substances that can be used as an immune‐modulating agent in poultry. The present study aimed to investigate the effects of Flammulina velutipes mushroom waste (FVW) on performance, immune response and serum immunity in growing layer hens..

OncologyImmune supportEnergy & fatigueMetabolic health

Enoki · 2019 · Journal Article · Journal of the science of food and agriculture

Dietary inclusion of mushroom (Flammulina velutipes) stem waste on growth performance and immune responses in growing layer hens.

BACKGROUND: Medicinal mushrooms contain biologically active substances that can be used as an immune-modulating agent in poultry. The present study aimed to investigate the effects of Flammulina velutipes mushroom waste (FVW) on performance, immune response and serum immunity in growing layer hens..

Immune supportEnergy & fatigueMetabolic health

Enoki · 2019 · Research Article · Animals: an open access journal from MDPI

Dietary Inclusion of Mushroom (Flammulina velutipes) Stem Waste on Growth Performance, Antibody Response, Immune Status, and Serum Cholesterol in Broiler Chickens.

This study was carried out to investigate the effects of mushroom (Flammulina velutipes) stem waste (MW) on growth performance, antibody response, immune status, and serum cholesterol in broiler chickens..

Shiitake · 2019 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Effect of heat treatments of Lentinula edodes mushroom on eritadenine concentration

High cholesterol levels in blood are a risky factor on the human health. Lentinula edodes mushroom produce the 2(R), 3(R)-dihydroxy-4-(9-adenil)-butyric acid, eritadenine.

Energy & fatigueMetabolic health

Shiitake · 2019 · Research Article · International journal of molecular sciences

GC⁻MS-Based Nontargeted and Targeted Metabolic Profiling Identifies Changes in the Lentinula edodes Mycelial Metabolome under High-Temperature Stress.

To clarify the physiological mechanism of the Lentinula edodes (L. edodes) response to high-temperature stress, two strains of L.

Zhu Ling · 2019 · Research Article · Nutrients

GPP (Composition of Ganoderma Lucidum Poly-saccharides and Polyporus Umbellatus Poly-saccharides) Enhances Innate Immune Function in Mice.

Modern research has found that Ganoderma lucidum polysaccharides (GLP) and Polyporus umbellatus polysaccharides (PUP) mainly exhibit immunoregulation. However, the immune function of a polysaccharide composition consisting of GLP and PUP has not been studied..

Immune supportMetabolic healthGut & microbiomeLiver support

Maitake · 2019 · Journal Article · Food & function

Grifola frondosa polysaccharides ameliorate lipid metabolic disorders and gut microbiota dysbiosis in high-fat diet fed rats.

The purpose of this study was to assess the potential effects of polysaccharides from edible mushroom Grifola frondosa (GFP) on lipid metabolic disorders and gut microbiota dysbiosis, and elucidate their possible regulatory mechanisms on lipid and cholesterol metabolism in high-fat diet (HFD)-exacerbated….

Immune supportEnergy & fatigueMetabolic healthLiver support

Yellow Morel · 2019 · Research Article · Oxidative medicine and cellular longevity

Hepatoprotective Effects of Morchella esculenta against Alcohol-Induced Acute Liver Injury in the C57BL/6 Mouse Related to Nrf-2 and NF-κB Signaling.

This study investigated the hepatoprotective effects of Morchella esculenta fruit body (ME) and the underlying mechanisms in mice with alcohol-induced acute liver injury. Systematic analysis revealed that ME contained 21 types of fatty acid, 17 types of amino acid, and 12 types of mineral..

Cordyceps · 2019 · Journal Article · Science China. Life sciences

Identification of microRNA-like RNAs in Ophiocordyceps sinensis.

Ophiocordyceps sinensis is well known as a traditional Chinese medicine and has widely been used for over 2,000 years to stimulate immune system, decrease blood pressure and to inhibit tumor growth..

Shiitake · 2019 · Research Article · Frontiers in microbiology

Lentinula edodes Mycelium as Effective Agent for Piroxicam Mycoremediation.

Pollution of the environment with inorganic and organic substances is one of the main problems in the world. For this reason, it is necessary to conduct researches for effective methods of biodegradation of xenobiotics, including drugs whose unmetabolized forms are introduced into the environment, especially into….

Oyster Mushroom · 2019 · Research Article · Frontiers in microbiology

Metabolic Response of Pleurotus ostreatus to Continuous Heat Stress.

Heat stress seriously threatens the growth of Pleurotus ostreatus. Various studies have been performed to study the resistance of P.

OncologyImmune supportMetabolic healthGut & microbiome

Enoki · 2019 · Journal Article · International journal of biological macromolecules

Preparation and in vitro absorption studies of a novel polysaccharide‑iron (III) complex from Flammulina velutipes.

Iron is essential in fundamental bioactivities, so it makes sense to improve the efficiency of iron on epithelial transport. In this work, a novel polysaccharide‑iron(III) complex (FVP-Fe(III)) was prepared from Flammulina velutipes with a specific structure..

Metabolic healthLiver support

Niu-Chang-Chih · 2019 · Journal Article · Chinese journal of natural medicines

Secondary metabolites of petri-dish cultured Antrodia camphorata and their hepatoprotective activities against alcohol-induced liver injury in mice.

Antrodia camphorata, a well-known and highly valued edible medicinal mushroom with intriguing activities like liver protection, has been traditionally used for the treatment of alcoholic liver disease. A.

Chaga · 2019 · Research Article · Molecules (Basel, Switzerland)

Simultaneous Use of Stimulatory Agents to Enhance the Production and Hypoglycaemic Activity of Polysaccharides from Inonotus obliquus by Submerged Fermentation.

This study aimed to determine the effect of applying stimulatory agents to liquid cultured Inonotus obliquus on the simultaneous accumulation of exo-polysaccharides (EPS) and their monosaccharide composition..

Immune supportMetabolic healthLiver support

Niu-Chang-Chih · 2019 · Research Article · RSC advances

Structural characterization and anti-inflammatory effect in hepatocytes of a galactoglucan from Antrodia camphorata mycelium.

The galactoglucan ACP2 was isolated from cultured Antrodia camphorata mycelium through anion-exchange column chromatography and Sephadex G-100 chromatography and shown to exhibit hepatoprotective function in L02 cells..

Maitake · 2019 · Research Article · BioMed research international

Structural Elucidation and Immune-Enhancing Effects of Novel Polysaccharide from Grifola frondosa.

Beta-glucan (β-glucan) is a macromolecule structure where glucose unit has bonded through β-glycosidic bond at 1 and 3 positions. It is well known as a natural immunomodulator without exhibiting any side effects via enhancing immunity..

OncologyEnergy & fatigueMetabolic healthLiver support

Niu-Chang-Chih · 2019 · Research Article · Molecules (Basel, Switzerland)

The Effects of Ergosta-7,9(11),22-trien-3β-ol from Antrodia camphorata on the Biochemical Profile and Exercise Performance of Mice.

Antrodia camphorata (AC) is a rare and unique mushroom that is difficult to cultivate. Previous studies have demonstrated the bioactivity of the compound Ergosta-7,9(11),22-trien-3β-ol (EK100) from AC in submerged culture..

Immune supportMetabolic healthGut & microbiomeLiver support

Maitake · 2019 · Research Article · International journal of molecular sciences

The Positive Effects of Grifola frondosa Heteropolysaccharide on NAFLD and Regulation of the Gut Microbiota.

: Non-alcoholic fatty liver disease (NAFLD) is a major public health problem in many countries. In this study, the ability of Grifola frondosa heteropolysaccharide (GFP) to ameliorate NAFLD was investigated in rats fed a high-fat diet (HFD)..

Chaga · 2019 · Research Article · Molecules (Basel, Switzerland)

Three-Phase Partitioning for the Extraction and Purification of Polysaccharides from the Immunomodulatory Medicinal Mushroom Inonotus obliquus.

Polysaccharides from the immunomodulatory medicinal mushroom Inonotus obliquus (IOPS) were extracted and purified using three-phase partitioning (TPP), which is an efficient, fast, safe, and green purification technique..

Metabolic healthLiver support

Chaga · 2018 · Research Article · International journal of molecular sciences

Actions of Inonotus obliquus against Hyperuricemia through XOD and Bioactives Screened by Molecular Modeling.

Inonotus obliquus is an edible mushroom and also a remedy against various diseases, especially metabolic syndrome. In this paper we report the actions of an ethanol extract of I.

Cognition & nervesMetabolic health

Lion's Mane · 2018 · Journal Article · Drug and chemical toxicology

Acute and developmental toxicity assessment of erincine A-enriched Hericium erinaceus mycelia in Sprague-Dawley rats.

This study aimed to establish an in vitro model to confirm the efficacy of erinacine A-enriched Hericium erinaceus (EAHE) mycelia and investigate its potential adverse effects in a preclinical experimental setting, including an assessment on the oral administration of EAHE mycelia in acute and prenatal developmental….

Energy & fatigueMetabolic healthLiver support

Niu-Chang-Chih · 2018 · Research Article · RSC advances

Antidiabetic and hypolipidemic activities of eburicoic acid, a triterpenoid compound from Antrodia camphorata, by regulation of Akt phosphorylation, gluconeogenesis, and PPARα in streptozotocin-induced diabetic mice.

The study is designed to examine the potential effects and underlying mechanisms of eburicoic acid (TRR), a compound from Antrodia camphorata, in streptozotocin (STZ)-induced diabetic mice..

Immune supportMetabolic healthSkin & hydration

Enoki · 2018 · Journal Article · Pakistan journal of pharmaceutical sciences

Cellulase-assisted extraction and anti-ultraviolet activity of polysaccharides from the root of Flammulina velutipes on Caenorhabditis elegans.

We investigated the cellulase-assisted extraction and anti-ultraviolet activity of water-soluble polysaccharides from the root of Flammulina velutipes on Caenorhabditis elegans..

Shiitake · 2018 · Journal Article · Gene

De novo transcriptomic analysis during Lentinula edodes fruiting body growth.

The fruiting body of Lentinula edodes is a popular edible mushroom, and extracts from the mycelium and the fruiting body of this species have diverse therapeutic potential. To gain insights into the molecular mechanisms underlying the fruiting body growth of L..

OncologyEnergy & fatigueMetabolic health

Niu-Chang-Chih · 2018 · Research Article · The Journal of veterinary medical science

Effects of Antrodia camphorata and Panax ginseng supplementation on anti-fatigue properties in mice

Antrodia camphorata and Panax ginseng are well-known medicinal plants in Taiwan folk and traditional Chinese medicine, which have been reported for multifunctional bioactivities..

Immune supportEnergy & fatigueMetabolic healthLiver support

Chaga · 2018 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Effects of polysaccharides from Inonotus obliquus and its chromium (III) complex on advanced glycation end-products formation, α-amylase, α-glucosidase activity and H2O2-induced oxidative damage in hepatic L02 cells.

In the present study, the antioxidant activity, anti-glycation activity, α-amylase, α-glucosidase inhibitory activity of polysaccharides from Inonotus obliquus (UIOPS) and its chromium (III) complex (UIOPC) were investigated..

Immune supportMetabolic healthGut & microbiome

Chaga · 2018 · Journal Article · Food research international (Ottawa, Ont.)

Effects of simulated gastrointestinal digestion in vitro on the chemical properties, antioxidant activity, α-amylase and α-glucosidase inhibitory activity of polysaccharides from Inonotus obliquus

This study was aimed to investigate the impacts of gastrointestinal digestion in vitro on the physicochemical properties and the biological activities of polysaccharides from Inonotus obliquus (UIOPS-1)..

OncologyImmune supportEnergy & fatigueMetabolic health

Maitake · 2018 · Journal Article · Journal of food science

Enzymatic Modification of Rice Bran Polysaccharides by Enzymes from Grifola Frondosa: Natural Killer Cell Cytotoxicity and Antioxidant Activity.

UNLABELLED: Rice bran polysaccharides (RBPSs) are the major active constituents of rice bran (RB). In this study, we utilized intracellular enzymes from Grifola frondosa to modify RBPSs, which were extracted from RB using ultrasound..

Energy & fatigueMetabolic health

Turkey Tail · 2018 · Journal Article · Ecotoxicology and environmental safety

Evaluation of a mixed simultaneous vinasse degradation treatment using Komagataeibacter kakiaceti GM5 and Trametes versicolor DSM 3086.

In the bioethanol industry and its derivative processes, 9-14 l of vinasse per liter of ethanol are obtained as residue, depending on whether or not a recirculation process is used..

Metabolic healthGut & microbiomeRespiratory

Enoki · 2018 · Journal Article · Plant disease

First Report of Ewingella americana Causing Bacterial Brown Rot Disease on Cultivated Needle Mushroom (Flammulina velutipes) in China

Needle mushroom (Flammulina velutipes) is one of the most industrially cultivated edible fungi in China. Its production is constrained by multiple abiotic and biotic stresses.

Immune supportMetabolic healthGut & microbiome

Lion's Mane · 2018 · Research Article · Journal of evidence-based integrative medicine

Lactobacillus fermentum HP3-Mediated Fermented Hericium erinaceus Juice as a Health Promoting Food Supplement to Manage Diabetes Mellitus.

The current study investigated the antidiabetic property of Lactobacillus fermentum HP3-mediated fermented Hericium erinaceus juice (FHJ) using male Wistar rats with streptozotocin-induced diabetes mellitus (DM). FHJ was prepared using boiled mushroom juice and L.

Immune supportMetabolic healthGut & microbiomeLiver support

Mesima · 2018 · Journal Article · Carbohydrate polymers

Polysaccharides extracted from Phellinus linteus ameliorate high-fat high-fructose diet induced insulin resistance in mice.

Phellinus linteus polysaccharide (PLP) has hypoglycemic effects, but mechanisms remain unclear. Male C57BL/6 J mice were either fed a normal diet (CON) or a high-fat high-fructose diet (HFD) for 16 weeks, and starting from week 12, HFD-fed animals in PLP group were orally given PLP..

Enoki · 2018 · Journal Article · Industrial crops and products

Production of resveratrol in Flammulina velutipes by combinatorial expression of its biosynthetic genes

Flammulina velutipes is cultivated commercially throughout the world because of its rich nutrients and bioactive substances, especially the precursor for resveratrol biosynthesis, p-coumaric acid. In this paper, a bioconversion system was established for the production of resveratrol in F.

OncologyImmune supportMetabolic healthLiver support

Enoki · 2018 · Journal Article · Carbohydrate polymers

Structural characteristics and bioactive properties of a novel polysaccharide from Flammulina velutipes.

A new water-soluble polysaccharide (FVP1) was extracted from Flammulina velutipes by traditional method "water extraction and alcohol precipitation" and purified by column chromatography. Physicochemical characterization showed that FVP1 was a homogeneous polysaccharide with a relative molecular weight of 54.78 kDa..

Maitake · 2018 · Journal Article · Carbohydrate polymers

Structural characterization and antidiabetic potential of a novel heteropolysaccharide from Grifola frondosa via IRS1/PI3K-JNK signaling pathways.

A novel heteropolysaccharide from Grifola frondosa named GFP-W has been isolated and purified by DEAE Sephadex A-52 chromatography. Gas chromatography, fourier transform infrared spectroscopy, one-dimensional (1H- and 13C-) and two-dimensional (1H-1H COSY, 1H-13C HSQC, and 1H-13C HMBC) nuclear magnetic resonance….

Wood Ear · 2018 · Journal Article · International journal of biological macromolecules

Structural characterization and immunomodulatory activity of exopolysaccharides from submerged culture of Auricularia auricula-judae.

Submerged culture of Auricularia auricula-judae has been documented, but there have been few studies on the structural characterization and medicinal properties of its exopolysaccharides. In present study, two exopolysaccharides, named CEPSN-1 and CEPSN-2, were isolated from submerged culture of A..

Yellow Morel · 2018 · Journal Article · Carbohydrate polymers

Structural characterization, in vitro and in vivo antioxidant activities of a heteropolysaccharide from the fruiting bodies of Morchella esculenta.

This study aimed to investigate the structural features, in vitro and in vivo antioxidant activities of a heteropolysaccharide from the fruiting bodies of Morchella esculenta (FMP-1). FMP-1 had an average molecular weight of 4.7 × 103 Da and consisted of mannose, glucose and galactose..

Lion's Mane · 2018 · Research Article · Polymers

Structural Properties and Macrophage Activation of Cell Wall Polysaccharides from the Fruiting Bodies of Hericium erinaceus.

In this study, water-soluble and alkali-soluble cell wall polysaccharides were obtained from fruiting body extracted residual micropowders of Hericium erinaceus, harvested at seven different growing stages..

Immune supportMetabolic healthSkin & hydration

Chaga · 2018 · Research Article · Molecules (Basel, Switzerland)

Structure Characterization and Hypoglycaemic Activities of Two Polysaccharides from Inonotus obliquus.

In the present study, two polysaccharides (HIOP1-S and HIOP2-S) were isolated and purified from Inonotus obliquus using DEAE-52 cellulose and Sephadex G-100 column chromatography. The structural characterization and in vitro and in vivo hypoglycaemic activities of these molecules were investigated..

Lion's Mane · 2018 · Journal Article · Food & function

Structure characterization of a novel polysaccharide from Hericium erinaceus fruiting bodies and its immunomodulatory activities.

A novel polysaccharide fraction (HEP-S) was extracted and isolated from the fruiting bodies of Hericium erinaceus. Structural characterization revealed that HEP-S had an average molecular weight of 1.83 × 104 Da and consisted of rhamnose, fucose, mannose, glucose and galactose at a molar ratio of 1.47: 0.93: 1.36:….

Turkey Tail · 2018 · Research Article · Frontiers in microbiology

The Algicidal Fungus Trametes versicolor F21a Eliminating Blue Algae via Genes Encoding Degradation Enzymes and Metabolic Pathways Revealed by Transcriptomic Analysis.

The molecular mechanism underlying the elimination of algal cells by fungal mycelia has not been fully understood. Here, we applied transcriptomic analysis to investigate the gene expression and regulation at time courses of Trametes versicolor F21a during the algicidal process..

Immune supportMetabolic healthLiver support

Chaga · 2017 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Anti-diabetic effects of Inonotus obliquus polysaccharides in streptozotocin-induced type 2 diabetic mice and potential mechanism via PI3K-Akt signal pathway.

Polysaccharides are the main components of mushroom Inonotus obliquus (I. obliquus) with antihyperglycemic activities.

Chaga · 2017 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Anti-diabetic effects of Inonotus obliquus polysaccharides-chromium (III) complex in type 2 diabetic mice and its sub-acute toxicity evaluation in normal mice.

Polysaccharides are important bioactive ingredients from Inonotus obliquus. This study aimed to synthesize and characterize a novel I.

Chaga · 2017 · Research Article · PloS one

Antidiabetic activities of polysaccharides separated from Inonotus obliquus via the modulation of oxidative stress in mice with streptozotocin-induced diabetes.

This study evaluated the effects of Inonotus obliquus polysaccharides (IOs) on diabetes and other underlying mechanisms related to inflammatory factors and oxidative stress in a mouse model of streptozotocin (STZ)-induced diabetes..

Energy & fatigueMetabolic healthLiver support

Niu-Chang-Chih · 2017 · Research Article · International journal of molecular sciences

Eburicoic Acid, a Triterpenoid Compound from Antrodia camphorata, Displays Antidiabetic and Antihyperlipidemic Effects in Palmitate-Treated C2C12 Myotubes and in High-Fat Diet-Fed Mice.

This study was designed to investigate the antidiabetic and antihyperlipidemic effects and mechanisms of eburicoic acid (TRR); one component of Antrodia camphorata in vitro and in an animal model for 14 weeks..

Maitake · 2017 · Journal Article · Food chemistry

Effects of different extraction temperatures on the physicochemical properties of bioactive polysaccharides from Grifola frondosa.

This study examined the effects of different extraction temperatures (70°C, 100°C and 121°C) on the physicochemical properties of water soluble polysaccharides (WSP; GF70, GF100 and GF121, respectively) from Grifola frondosa (GF) fruiting bodies, and evaluating their effects on nitric oxide (NO) production in….

OncologyImmune supportMetabolic healthGut & microbiome

Chaga · 2017 · Research Article · International journal of biological macromolecules

Identification of Inonotus obliquus polysaccharide with broad-spectrum antiviral activity against multi-feline viruses.

Inonotus obliquus polysaccharides (IOPs) are a potential drug for the prevention and treatment of cancer, cardiopathy, diabetes, AIDs, pancreatitis and other diseases. In this study, we found that IOP can act as a broad-spectrum antiviral drug against feline viruses in the in vitro experiment..