MycoData

The vegetative mycelium of Pleurotus ostreatus (oyster mushroom) exhibits the ability to reduce nematode populations. This property may be utilized in integrated management programs targeting harmful nematodes such as Heterodera schachtii, a major pest of sugar beet crops..

Gut & microbiome

High relevance

King Oyster · 2025 · Research Article · Foods (Basel, Switzerland)

The Performance of Pleurotus eryngii β-Glucans on Protein Digestion and the Release of Free Amino Acids in the Bloodstream of Obese Adults.

Pleurotus eryngii is an edible mushroom with previously characterized β-glucans. Its potential to ameliorate postprandial glycemia and regulate appetite at the postprandial state has been previously shown.

Energy & fatigueMetabolic healthGut & microbiome

High relevance

King Oyster · 2025 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Unlocking sustainable protein from Pleurotus eryngii: Enzymatic degradation of cell wall enhances digestibility in mycelia and fruiting bodies

The bioavailability of fungal protein is constrained by the resilient chitin-based cell wall. This study aimed to enhance the digestibility of Pleurotus eryngii protein—from both fruiting bodies and mycelia—through enzymatic cell wall disruption using lywallzyme I, lywallzyme II, and snailase..

Gut & microbiome

High relevance

Maitake · 2024 · Journal Article · International journal of biological macromolecules

A novel angiotensin I-converting enzyme inhibitory peptide APPLRP from Grifola frondosa ameliorated the Ang II-induced vascular modeling in zebrafish model by mediating smooth muscle cells.

Grifola frondosa has garnered significant popularity as an edible mushroom attributable to its exceptional taste and nutritional benefits. This study isolated APPLRP, a potent ACE-inhibitory peptide, from the alcohol-soluble fraction of Grifola frondosa..

Energy & fatigueMetabolic healthGut & microbiomeSkin & hydration

High relevance

Cordyceps · 2024 · Journal Article · Journal of pharmaceutical and biomedical analysis

Amelioration of hyperuricemia by cordycepin and Cordyceps militaris aqueous extract in mice via modulating gut microbiota and restoring metabolic profile.

In this study, we first screened and evaluated the inhibitory effects of seven medicinal fungi on diseases such as hyperuricemia (HUA). Then, using metabolomics and gut microbiome methods, the focus was on analyzing and evaluating the effects of the aqueous extract of Cordyceps..

Metabolic healthGut & microbiome

High relevance

Cordyceps · 2024 · Journal Article · International journal of food science & technology

Analysis of bioactive compounds in Cordyceps militaris fruiting bodies and dietary supplements: in vitro bioaccessibility determination in artificial digestive juices

In recent years, Cordyceps militaris has garnered increased attention in both scientific research and popular culture, exemplified by references in the entertainment industry, such as ‘The Last Of Us’..

Gut & microbiome

High relevance

Reishi · 2024 · Journal Article · Drug and chemical toxicology

Assessment of redox homeostasis via genotoxicity, cytotoxicity, apoptosis and NRF-2 in colorectal cancer cell lines after treatment with Ganoderma lucidum extract.

This study aimed to investigate the cytotoxic and apoptotic effects of Ganoderma lucidum, Pleurotus ostreatus, Pleurotus eryngii, and Inonotus hispidus fungal extracts on HT-29 and HCT-116 colorectal cancer cell lines and to search the DNA damage and oxidative stress caused by these extracts..

OncologyGut & microbiome

High relevance

Chaga · 2024 · Research Article · Biomolecules

Chaga Mushroom Triterpenoids Inhibit Dihydrofolate Reductase and Act Synergistically with Conventional Therapies in Breast Cancer.

Inonotus obliquus (Chaga) is a medicinal mushroom with several pharmacological properties that is used as a tea in traditional Chinese medicine. In this study, Chaga water extract was digested in vitro to mimic the natural processing and absorption of its biocomponents when it is consumed as functional beverage, and….

OncologyImmune supportGut & microbiome

High relevance

Cordyceps · 2024 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Changes in aggregation properties and the metabolite production of probiotics following treatment with polysaccharides derived from the edible mushroom Cordyceps militaris

Low-molecular-weight exopolysaccharides of Cordyceps militaris (LCMP), obtained by enzymatically digesting the exopolysaccharide produced by C. militaris, were purified and found to be comprised of 77.9% mannose and 22.1% glucose..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Oyster Mushroom · 2024 · Research Article · Journal of fungi (Basel, Switzerland)

Comparative Analysis of Freeze-Dried Pleurotus ostreatus Mushroom Powders on Probiotic and Harmful Bacteria and Its Bioactive Compounds.

Pleurotus ostreatus (oyster mushroom) holds excellent promise worldwide, bringing several opportunities and augmenting the tool sets used in the biotechnology field, the food industry, and medicine. Our study explores the antimicrobial and probiotic growth stimulation benefits of freeze-dried P..

Immune supportGut & microbiomeSkin & hydration

High relevance

Enoki · 2024 · Journal Article · International journal of biological macromolecules

Comprehensive evaluation of Flammulina velutipes residues polysaccharide based on in vitro digestion and human fecal fermentation.

Flammulina velutipes residues (FVR) are the waste culture medium derived from the collection of Flammulina velutipes fruiting bodies, with an annual output that remains largely unexplored..

Immune supportGut & microbiome

High relevance

Cordyceps · 2024 · Research Article · Antioxidants (Basel, Switzerland)

Cordyceps militaris Extract and Cordycepin Alleviate Oxidative Stress, Modulate Gut Microbiota and Ameliorate Intestinal Damage in LPS-Induced Piglets.

Cordycepin is considered a major bioactive component in Cordyceps militaris extract. This study was performed to evaluate the ameliorative effect of Cordyceps militaris extract (CME) and cordycepin (CPN) supplementation on intestinal damage in LPS-challenged piglets..

Immune supportGut & microbiome

High relevance

Cordyceps · 2024 · Research Article · International journal of molecular sciences

Cordyceps militaris Grown on Germinated Rhynchosia nulubilis (GRC) Encapsulated in Chitosan Nanoparticle (GCN) Suppresses Particulate Matter (PM)-Induced Lung Inflammation in Mice.

Cordyceps militaris grown on germinated Rhynchosia nulubilis (GRC) exerts various biological effects, including anti-allergic, anti-inflammatory, and immune-regulatory effects..

Immune supportGut & microbiomeRespiratory

High relevance

Niu-Chang-Chih · 2024 · Review · Frontiers in pharmacology

Current and further outlook on the protective potential of Antrodia camphorata against neurological disorders.

Prevalent neurological disorders such as Alzheimer's disease, Parkinson's disease, and stroke are increasingly becoming a global burden as society ages. It is well-known that degeneration and loss of neurons are the fundamental underlying processes, but there are still no effective therapies for these neurological….

Cognition & nervesGut & microbiome

High relevance

King Oyster · 2024 · Journal Article · Food Research International

Dietary intake of whole king oyster mushroom (Pleurotus eryngii) attenuated obesity via ameliorating lipid metabolism and alleviating gut microbiota dysbiosis

There is a growing interest in employing whole food-based strategies to prevent chronic diseases, owing to the potential synergistic interactions among various bioactive components found within whole foods..

Metabolic healthGut & microbiomeLiver support

High relevance

King Oyster · 2024 · Journal Article · Food research international (Ottawa, Ont.)

Dietary intake of whole king oyster mushroom (Pleurotus eryngii) attenuated obesity via ameliorating lipid metabolism and alleviating gut microbiota dysbiosis.

Metabolic healthGut & microbiomeLiver support

High relevance

Cordyceps · 2024 · Research Article · Journal of animal science

Effect of cordyceps militaris on growth performance, antioxidant capacity, and intestinal epithelium functions in weaned pigs.

To explore the effects of cordyceps militaris (CM) on growth performance and intestinal epithelium functions, 180 weaned pigs were randomly assigned into 5 treatments with 6 replicate pens per treatment (6 pigs per pen)..

Immune supportEnergy & fatigueGut & microbiome

High relevance

Reishi · 2024 · Journal Article · Aquaculture

Effects of dietary reishi mushroom (Ganoderma lucidum) on the growth performance of Nile tilapia, Oreochromis niloticus juveniles

In aquaculture, several medicinal mushrooms have been successfully used as prebiotics, with attractive growth-stimulant, immune-modulatory, and antioxidant functions for several finfish species..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Reishi · 2024 · Randomized Controlled Trial, Veterinary · Animal biotechnology

Effects of JUNCAO Ganoderma lucidum polysaccharide peptide on slaughter performance and intestinal health of Minxinan black rabbits.

This experiment was conducted to investigate the effects of JUNCAO Ganoderma lucidum polysaccharide peptide (JCGLPP) on slaughter performance and intestinal health of Minxinan black rabbits, which aimed to provide the basis for the application of JCGLPP in meat rabbits..

Immune supportEnergy & fatigueGut & microbiome

High relevance

Oyster Mushroom · 2024 · Research Article · Poultry science

Effects of oyster mushroom (Pleurotus ostreatus) stem residue supplementation on growth performance, meat quality and health status of broilers.

Oyster mushroom stem residue, a by-product with medicinal and nutritive values, might be a prospective feed supplement in poultry nutrition. The study focused on evaluating the impact of oyster mushroom (Pleurotus ostreatus) stem residue (OMSR) powder supplementation on growth performance, carcass traits, meat….

Energy & fatigueGut & microbiome

High relevance

King Oyster · 2024 · Journal Article · Food chemistry

Effects of selenium biofortification on Pleurotus eryngii protein structure and digestive properties and its mitigation of lead toxicity: An in vitro and in vivo study.

The development of safe and efficient dietary selenium sources to promote lead excretion is of great importance for public health. In this research, proteins from original Pleurotus eryngii (PEP) and Se-enriched P..

Gut & microbiome

High relevance

Oyster Mushroom · 2024 · Research Article · Animals: an open access journal from MDPI

Effects of Spent Substrate of Oyster Mushroom (Pleurotus ostreatus) on Feed Utilization and Liver Serum Indices of Hu Sheep from the Perspective of Duodenal Microorganisms.

This study aimed to evaluate the effects of Pleurotus ostreatus spent mushroom substrate (P.SMS), which is characterized by high production but low utilization, on feed utilization and liver serum indices from the perspective of duodenal microorganisms..

Gut & microbiomeLiver support

High relevance

Oyster Mushroom · 2024 · Journal Article · Physiological and Molecular Plant Pathology

Efficacy of Pleurotus ostreatus mycelia as bioinoculant to improve growth of pepper plant and protect against wilt causing Fusarium oxysporum

Among the different value added uses of mushroom, vegetative mycelia of Pleurotus ostreatus can be explored as a bio-inoculant for sustainable agriculture use. From three fruit-bodies of Pleurotus ostreatus, tissue cultures were established, were used for DNA preparation and biochemical tests..

Gut & microbiome

High relevance

King Oyster · 2024 · Research Article · Journal of fungi (Basel, Switzerland)

Enhancing Digestibility and Intestinal Peptide Release of Pleurotus eryngii Protein: An Enzymatic Approach.

Pleurotus eryngii is a tasty and low-calorie mushroom containing abundant high-quality protein. This study aims to improve the digestibility of P.

Gut & microbiome

High relevance

Enoki · 2024 · Research Article · Foods (Basel, Switzerland)

Enhancing the Hypolipidemic and Functional Properties of Flammulina velutipes Root Dietary Fiber via Steam Explosion.

Flammulina velutipes is an edible mushroom widely cultivated in China. As a by-product of Flammulina velutipes, the roots are rich in high-quality dietary fiber (DF)..

Metabolic healthGut & microbiomeLiver support

High relevance

King Oyster · 2024 · Research Article · Nutrients

Evaluation of Physicochemical Properties and Prebiotics Function of a Bioactive Pleurotus eryngii Aqueous Extract Powder Obtained by Spray Drying.

A bioactive Pleurotus eryngii aqueous extract powder (SPAE) was obtained by spray drying and its performance in terms of physicochemical properties, in vitro digestion, inflammatory factors, and modulation of the intestinal microbiota was explored..

Immune supportEnergy & fatigueGut & microbiome

High relevance

Shiitake · 2024 · Journal Article · International journal of biological macromolecules

Extraction of chitin-glucan complex from shiitake (Lentinula edodes) fruiting bodies using natural deep eutectic solvents and its prebiotic potential.

Chitin-glucan complex (CGC) is an emerging novel prebiotic with numerous physiological activities in amelioration of clinical manifestations. In the present work, natural deep eutectic solvent (NADES), ultrasonication, and submerged fermentation using probiotic microorganisms were deployed for the extraction of CGC….

Immune supportGut & microbiome

High relevance

Reishi · 2024 · Preprint · journal metadata

Ganoderma lucidum alleviates kidney aging by modulating gut microbiota

Background Ganoderma lucidum, a renowned traditional Chinese medicine known for its multiple health benefits, including anti-aging effect, has the ability to influence gut microbiota. However, its specific role in alleviating aging via gut microbiota has not been thoroughly investigated..

Metabolic healthGut & microbiomeSkin & hydration

High relevance

Reishi · 2024 · Journal Article · Journal of ethnopharmacology

Ganoderma lucidum ethanol extracts ameliorate hepatic fibrosis and promote the communication between metabolites and gut microbiota g_Ruminococcus through the NF-κB and TGF-β1/Smads pathways.

ETHNOPHARMACOLOGICAL RELEVANCE: Ganoderma lucidum, a traditional edible medicinal mushroom, has been widely reported to improve liver diseases as a dietary intervention for people..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Reishi · 2024 · Journal Article · International journal of biological macromolecules

Ganoderma lucidum polysaccharide promotes broiler health by regulating lipid metabolism, antioxidants, and intestinal microflora.

Ganoderma lucidum polysaccharides (GLP) are the primary bioactive macromolecular compounds of Ganoderma lucidum, possessing antioxidant and immunomodulatory effects. Hot water extract of Juncao-substrate Ganoderma Lucidum residue (HWE-JGLR) is abundant in GLP..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Reishi · 2024 · Research Article · Heliyon

Ganoderma lucidum polysaccharides reduce the severity of acute liver injury by improving the diversity and function of the gut microbiota.

Acute liver injury (ALI) is an abnormal liver function caused by oxidative stress, inflammation and other mechanisms.The interaction between intestine and liver plays an important role in ALI, and natural polysaccharides can participate in the regulation of ALI by regulating the composition of intestinal flora..

Immune supportGut & microbiomeLiver support

High relevance

Cordyceps · 2024 · Journal Article · Journal of ethnopharmacology

Genotoxicity, acute and sub-acute toxicity profiles of methanolic Cordyceps militaris (L.) Fr. extract in Swiss Albino Mice.

ETHNOPHARMACOLOGICAL RELEVANCE: Cordyceps militaris, a traditional medicinal fungus, parasitizes the intestines of lepidopteron pupae or larvae, predominantly during the winter, and undergoes fruiting in the summer or autumn. Compounds extracted from C..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Cordyceps · 2024 · Journal Article · International journal of medicinal mushrooms

Hot Water Extract of the Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes) Fruiting Body Activates Myeloid Dendritic Cells through A Dectin-1-Mediated Pathway.

The traditional use of Cordyceps militaris, an entomopathogenic fungus, in East Asian medicine has been well documented. Our previous study revealed that the fruiting body powder of C..

OncologyImmune supportGut & microbiome

High relevance

King Oyster · 2024 · Research Article · Foods (Basel, Switzerland)

Identification of Peptides from Edible Pleurotus eryngii Mushroom Feet and the Effect of Delaying D-Galactose-Induced Senescence of PC12 Cells Through TLR4/NF-κB/MAPK Signaling Pathways.

Pleurotus eryngii mushroom has been proven to have anti-aging bioactivities. However, few studies have focused on edible Pleurotus eryngii mushroom feet peptides (PEMFPeps)..

Energy & fatigueGut & microbiomeSkin & hydration

High relevance

Shiitake · 2024 · Research Article · Foods (Basel, Switzerland)

Impact of Incorporating Shiitake Mushrooms (Lentinula edodes) on Microbial Community and Flavor Volatiles in Traditional Jiuqu.

Jiuqu is one of the important raw materials for brewing Chinese rice wine (Huangjiu), often known as the "bone of wine". In this study, the microbial community and flavor substances of Jiuqu made with different amounts of shiitake mushroom (Lentinula edodes) were investigated through high-throughput sequencing….

Metabolic healthGut & microbiome

High relevance

Yellow Morel · 2024 · Research Article · Food chemistry: X

In vitro digestion and fecal fermentation behaviors of exopolysaccharide from Morchella esculenta and its impacts on hypoglycemic activity via PI3K/Akt signaling and gut microbiota modulation.

This study aimed to evaluate the effects of gastrointestinal digestion on the physicochemical properties and hypoglycemic activity of extracellular polysaccharides from Morchella esculenta (MEPS)..

Immune supportMetabolic healthGut & microbiome

High relevance

King Oyster · 2024 · Journal Article · Food & function

In vitro gastrointestinal digestion and fecal fermentation of Pleurotus eryngii proteins extracted using different methods: insights for the utilization of edible mushroom-based proteins as novel nutritional and functional components.

Pleurotus eryngii (P. eryngii) protein is considered a high-quality protein because it is rich in essential amino acids and displays multiple significant functional characterizations that vary with its fabrication processes.

Immune supportMetabolic healthGut & microbiome

High relevance

Cordyceps · 2024 · Preprint · journal metadata

In vitro simulation of oral gastric intestinal digestion and fecal fermentation of Cordyceps militaris polysaccharides reveal its digestion profile and effect on the modulation of the gut microbiota

Abstract Background: Polysaccharides isolated from Cordyceps militaris mycelia (IPS) are natural polymer compounds composed of monosaccharides, structurally diverse and exhibit various metabolic and biological activities..

Immune supportMetabolic healthGut & microbiome

High relevance

Chaga · 2024 · Journal Article · Toxicology mechanisms and methods

Inonotus obliquus aqueous extract inhibits intestinal inflammation and insulin metabolism defects in Drosophila.

In biomedical research, the fruit fly (Drosophila melanogaster) is among the most effective and flexible model organisms. Through the use of the Drosophila model, molecular mechanisms of human diseases can be investigated and candidate pharmaceuticals can be screened..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

King Oyster · 2024 · Journal Article · Food & function

Interactions between intestinal microbial fermentation products of Pleurotus eryngii polysaccharide with gut mucus.

Recently, Pleurotus eryngii (P. eryngii) polysaccharide (PEP) has received a lot of attention from many researchers as the primary active substance.

Immune supportGut & microbiome

High relevance

Oyster Mushroom · 2024 · Journal Article · Chemistry & biodiversity

Investigating the Anticancer Effects of Pleurotus ostreatus Polysaccharide on G0/G1 Cell Cycle Arrest and Apoptosis in Ehrlich Ascites Carcinoma Cells.

Cancer is one of the leading causes of mortality worldwide. Despite the advancement of cancer treatment by various means including surgery, chemotherapy etc, cancer is still a challenging disease to manage..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Snow Fungus · 2024 · Journal Article · International journal of biological macromolecules

Low molecular weight polysaccharide of Tremella fuciformis exhibits stronger antioxidant and immunomodulatory activities than high molecular weight polysaccharide.

Low molecular weight polysaccharides had higher bio-activity and bioavailability compared to ultra-high molecular weight polysaccharides, this study aimed to obtain low molecular weight polysaccharides from Tremella fuciformis (TFLP) by using high-temperature and high-pressure assisted hydrochloric acid method to….

Immune supportGut & microbiome

High relevance

King Oyster · 2024 · Journal Article · Food chemistry

Metabolomics study of dietary Pleurotus eryngii β-type glycosidic polysaccharide on colitis induced by dextran sodium sulfate in mice - Exploration for the potential metabolic indicators in urine and serum.

Pleurotus eryngii, an edible mushroom recognized for its potent polysaccharides, demonstrates significant regulatory effects on metabolic processes. β-glucan (WPEP) derived from P..

Immune supportMetabolic healthGut & microbiome

High relevance

Shiitake · 2024 · Journal Article · Bioresource technology

Peach palm shells (Bactris gasipaes Kunth) bioconversion by Lentinula edodes: Potential as new bioproducts for beef cattle feeding.

This paper aims to develop and assess the in vitro effects on ruminal fermentation and greenhouse gas parameters of new bioproducts for beef cattle diets, carried out by solid-state fermentation of peach palm shells colonized by Lentinula edodes (SSF) and after Shiitake mushroom cultivation in axenic blocks (SMS)..

Gut & microbiome

High relevance

King Oyster · 2024 · Journal Article · International journal of biological macromolecules

Pleurotus eryngii polysaccharides alleviate aflatoxin B1-induced liver inflammation in ducks involving in remodeling gut microbiota and regulating SCFAs transport via the gut-liver axis.

Aflatoxin B1 (AFB1) is one of the most widespread contaminants in agricultural commodities. Pleurotus eryngii (PE) is widely used as a feed additive for its anti-inflammatory properties, and its major active substance is believed to be polysaccharides..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

King Oyster · 2024 · Journal Article · Fish & shellfish immunology

Pleurotus eryngii root waste and soybean meal co-fermented protein improved the growth, immunity, liver and intestinal health of largemouth bass (Micropterus salmoides).

The present study aimed to evaluate the effect of king oyster mushroom (Pleurotus eryngii) root waste and soybean meal co-fermented protein (CFP) on growth performance, feed utilization, immune status, hepatic and intestinal health of largemouth bass (Micropterus salmoides)..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Almond Mushroom · 2024 · Journal Article · Journal of agricultural and food chemistry

Polysaccharide Isolated from Agaricus blazei Murill Alleviates Intestinal Ischemia/Reperfusion Injury through Regulating Gut Microbiota and Mitigating Inflammation in Mice.

Intestinal ischemia-reperfusion (I/R) injury is a serious disease in medical settings, and gut dysbiosis is a major contributor to its development. Polysaccharides from Agaricus blazei Murill (ABM) showed a range of pharmacological activities, yet no studies assessed the potential of ABM polysaccharides for….

Immune supportGut & microbiome

High relevance

Cordyceps · 2024 · Journal Article · Food Research International

Polysaccharides from Cordyceps militaris prevent obesity in association with modulating gut microbiota and metabolites in high-fat diet-fed mice

Improved gut microbes and nutritious metabolites have been considered as the mediators of health benefits from indigestible polysaccharides, but their role in the anti-obesity effect of polysaccharides from Cordyceps militaris (CMP) remains elusive..

Immune supportMetabolic healthGut & microbiome

High relevance

Chaga · 2024 · Journal Article · Industrial crops and products

Polysaccharides from Inonotus obliquus employing subcritical water extraction: Extraction optimization, physiochemical properties and bioactivities analysis

As one of the main components in Inonotus obliquus, polysaccharides was potentially to be developed for the special physiochemical properties and bioactivity. However, the low extraction efficiency of Inonotus obliquus polysaccharides (IOP) significantly hindered the in-depth research and development..

Immune supportGut & microbiome

High relevance

Oyster Mushroom · 2024 · Review · Foods (Basel, Switzerland)

Pre- and Postharvest Strategies for Pleurotus ostreatus Mushroom in a Circular Economy Approach.

Mushroom cultivation presents a viable solution for utilizing agro-industrial byproducts as substrates for growth. This process enables the transformation of low-economic-value waste into nutritional foods..

Gut & microbiome