MycoData

Reishi · 2025 · Journal Article · International journal of biological macromolecules

Water-soluble β-glucan from G. lucidum as a potential functional food ingredient with gut microbiota-regulating and immune-enhancing activities.

Ganoderma lucidum is a nutraceutical and a traditional medicinal mushroom. β-glucans are the predominant bioactive components in G.

Immune supportEnergy & fatigueGut & microbiome

Reishi · 2024 · Journal Article · Journal of the science of food and agriculture

Anti-inflammatory activity of β-glucans from different sources before and after fermentation by fecal bacteria in vitro.

BACKGROUND: β-Glucans are widely sourced and have various physiological effects, including anti-inflammatory effects. However, the strength of the anti-inflammatory activity of β-glucans from different sources remains unknown due to the lack of rapid and effective biomarkers..

Oyster Mushroom · 2024 · Journal Article · Journal of agricultural and food chemistry

Buddlejasaponin IVb Alleviates DSS-Induced Ulcerative Colitis through the Nrf2/GPX4 Pathway and Gut Microbiota Modulation.

Buddlejasaponin IVb (BJP-IVb), a triterpenoid saponin derived from Pleurotus ostreatus, is abundant in bioactive constituents. However, its potential therapeutic benefits and underlying mechanism of action against ulcerative colitis (UC) remain elusive..

Metabolic healthGut & microbiomeLiver support

Reishi · 2024 · Journal Article · Journal of the science of food and agriculture

Compound chenpi tea consumption reduces obesity-related metabolic disorders by modulating gut microbiota and serum metabolites in mice.

BACKGROUND: Compound chenpi tea (CCT) is a popular herbal beverage made from citri reticulatae pericarpium, Ganoderma lucidum, and pu-erh tea. This study aimed to investigate the anti-obesity effect of CCT in mice fed a high-fat diet (HFD) and to explore the potential mediators by 16S ribosomal RNA sequencing and….

Chaga · 2024 · Journal Article · International journal of medicinal mushrooms

Crude Polysaccharides from Mushrooms Elicit an Anti-Allergic Effect Against Type 1 Allergy In Vitro.

Type 1 allergic disease is a global challenge, hence the search for alternative therapies. Mushrooms have several medicinal and health benefits.

OncologyImmune supportMetabolic healthGut & microbiome

Shiitake · 2024 · Research Article · Cancer medicine

Edodes Cultured Extract Regulates Immune Stress During Puberty and Modulates MicroRNAs Involved in Mammary Gland Development and Breast Cancer Suppression.

BACKGROUND: Immune stressors, such as lipopolysaccharides (LPS), profoundly affect microbiota balance, leading to gut dysbiosis. This imbalance disrupts the metabolic phenotype and structural integrity of the gut, increasing intestinal permeability..

Immune supportEnergy & fatigueGut & microbiome

Reishi · 2024 · Journal Article · Animals: an open access journal from MDPI

Effects of Plant Polysaccharides Combined with Boric Acid on Digestive Function, Immune Function, Harmful Gas and Heavy Metal Contents in Faeces of Fatteners.

The experiment aimed to investigate the effects of plant polysaccharides combined with boric acid on digestive function, immune function and harmful gas and heavy metal contents in the faeces of fatteners..

Lion's Mane · 2024 · Research Article · Current research in food science

Efficient conversion of tea residue nutrients: Screening and proliferation of edible fungi.

Despite lignocellulose hindering the extraction of intracellular components, tea residue can serve as an excellent substrate for fungal fermentation owing to their lignocellulose-degrading abilities..

Cognition & nervesEnergy & fatigueGut & microbiome

Turkey Tail · 2024 · Journal Article · Chemosphere

Enzymatic degradability of diclofenac ozonation products: A mechanistic analysis.

The treatment of waterborne micropollutants, such as diclofenac, presents a significant challenge to wastewater treatment plants due to their incomplete removal by conventional methods. Ozonation is an effective technique for the degradation of micropollutants..

Turkey Tail · 2024 · Journal Article · Plant disease

First Report of Cobweb Disease in Auricularia cornea var. Li. Caused by Hypomyces mycophilus in China

Auricularia cornea var. Li.

Oyster Mushroom · 2024 · Journal Article · Food Research International

Flours from fermented lentil and quinoa grains as ingredients with new techno-functional properties

The need to provide novel, nutritious plant-based products necessitate seeking high-value, sustainable protein sources, like quinoa and lentils, having an increased digestibility and lacking antinutrients. Fungal fermentation has evidenced enhanced nutritional value of flours obtained from these grains..

Oyster Mushroom · 2024 · Journal Article · Frontiers in microbiology

From waste to protein: a new strategy of converting composted distilled grain wastes into animal feed.

Distilled grain waste (DGW) is rich in nutrients and can be a potential resource as animal feed. However, DGW contains as much as 14% lignin, dramatically reducing the feeding value.

Reishi · 2024 · Journal Article · Journal of agricultural and food chemistry

Ganoderic Acid A Mitigates Inflammatory Bowel Disease through Modulation of AhR Activity by Microbial Tryptophan Metabolism.

Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a complex gastrointestinal condition influenced by genetic, microbial, and environmental factors, among which the gut microbiota plays a crucial role and has emerged as a potential therapeutic target..

Oyster Mushroom · 2024 · Research Article · Foods (Basel, Switzerland)

Impact of Fava Bean (Vicia faba) Processing on Quality Characteristics and Digestibility of a Protein-Rich Snack.

The impact of fava bean processing methods (soaking, autoclaving, fermentation) on a legume-based bars' quality, protein characteristics, and digestibility was shown..

Oyster Mushroom · 2024 · Journal Article · Microorganisms

Impact of Spent Mushroom Substrate Combined with Hydroponic Leafy Vegetable Roots on Pleurotus citrinopileatus Productivity and Fruit Bodies Biological Properties.

Agricultural activities produce large quantities of organic byproducts and waste rich in lignocellulosic materials, which are not sufficiently utilized. In this study, alternative agricultural waste products, namely, spent mushroom substrate (SMS) from the cultivation of edible Pleurotus ostreatus mushrooms and the….

Energy & fatigueMetabolic healthGut & microbiome

Enoki · 2024 · Research Article · Animals: an open access journal from MDPI

Innovation and Utilization of Functional Feed Additives from Maize By-Products in Broiler Chickens.

Supplementation with spent mushroom substrate (SMS) as an exogenous enzyme in broiler diets represents a promising nutritional strategy to enhance production efficiency and reduce costs..

Lion's Mane · 2024 · Journal Article · International journal of biological macromolecules

Interactions between soluble dietary fibers from three edible fungi and gut microbiota.

Edible fungi are emerging as a valuable dietary fiber source with health benefits, where their bioactivity hinges on their structure. This study targets the structure-activity relationship of soluble dietary fibers from Lentinus edodes (LESDF), Agaricus bisporus (ABSDF), and Hericium erinaceus (HESDF), focusing on….

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Shiitake · 2024 · Journal Article · Food Hydrocolloids

Interactions between sorghum starch and mushroom polysaccharides and their effects on starch gelatinization and digestion

This study aimed at gaining insight into the mechanism of interactions between sorghum starch and mushroom polysaccharides (MPs) obtained from three cultivars Lentinula edodes (LEP), Auricularia auricula (AAP), and Tremella fuciformis polysaccharides (TFP) in relation to gelatinization, retrogradation and….

Immune supportCognition & nervesGut & microbiome

Snow Fungus · 2024 · Journal Article · International journal of biological macromolecules

Multiple fingerprint and pattern recognition analysis on polysaccharides of four edible mushrooms.

Quality analysis of edible mushrooms based on polysaccharides is generally difficult due to their complicated structures and hard separation. Here, multiple fingerprint analysis of polysaccharides based on chromatographic and spectrometric techniques were developed, and then applied in comparative analysis of….

Oyster Mushroom · 2024 · Journal Article · Journal of the science of food and agriculture

Novel techniques for the mass production of nutritionally improved, fungus-treated lignocellulosic biomass for ruminant nutrition.

BACKGROUND: Laboratory-scale experiments have shown that treatment with selective lignin-degrading white-rot fungi improves the nutritional value and ruminal degradability of lignocellulosic biomass (LCB)..

Oyster Mushroom · 2024 · Journal Article · Food research international (Ottawa, Ont.)

Protein digestibility and ACE inhibitory activity of fermented flours in older adults and standard gastrointestinal simulation.

Consumption of essential amino acids responsible for muscle protein synthesis is important in preventing sarcopenia among older individuals. This population may experience gastrointestinal disorders that inhibit protein digestibility, making it crucial to address..

Oyster Mushroom · 2024 · Journal Article · World J Microbiol Biotechnol

Strategies for producing probiotic biomass and postbiotics from Akkermansia muciniphila in submerged cultivations incorporating prebiotic sources

This research propounds an innovative technology focused on sustainability to increase the biomass yield of Akkermansia muciniphila, the next-generation probiotic, using prebiotic sources to replace or reduce animal mucin levels..

Oyster Mushroom · 2024 · Journal Article · World journal of microbiology & biotechnology

Strategies for producing probiotic biomass and postbiotics from Akkermansia muciniphila in submerged cultivations incorporating prebiotic sources.

Metabolic healthGut & microbiomeLiver support

Reishi · 2024 · Research Article · Foods (Basel, Switzerland)

Synthesis of Ganoderic Acids Loaded Zein-Chitosan Nanoparticles and Evaluation of Their Hepatoprotective Effect on Mice Given Excessive Alcohol.

Ganoderma lucidum, used in East Asia for its health benefits, contains ganoderic acids (GA) which have various pharmacological activities but are limited by poor water solubility and low oral bioaccessibility..

Shiitake · 2024 · Research Article · Animals: an open access journal from MDPI

The Canine Gut Health: The Impact of a New Feed Supplement on Microbiota Composition.

This study aimed to determine the impact of a novel formulation of a supplement composed of the natural ingredients, bromelain, quercetin, and Lentinula edodes, on the gut microbiota of healthy adult dogs..

Immune supportMetabolic healthGut & microbiomeLiver support

Shiitake · 2024 · Journal Article · Food & function

The dose-dependent mechanism behind the protective effect of lentinan against acute alcoholic liver injury via proliferating intestinal probiotics.

Acute alcoholic liver injury (AALI) is a widespread disease that can develop into hepatitis, liver fibrosis, and cirrhosis. In severe cases, it can be life-threatening, while drug treatment presents various side effects..

Gut & microbiomeRespiratory

Cordyceps · 2024 · Journal Article · Journal of ethnopharmacology

Traditional medicinal knowledge of Sherpa people: Assessment in Xizang, China.

ETHNOPHARMACOLOGICAL RELEVANCE: The people of the Pan-Himalayan region are among the most isolated and economically disadvantaged populations worldwide. The Sherpa people, located along the China and Nepal border, rely largely on the natural environment to access essential healthcare services..

Reishi · 2024 · Journal Article · Bioprocess and biosystems engineering

Use of sawdust for production of ligninolytic enzymes by white-rot fungi and pharmaceutical removal.

Use of white-rot fungi for enzyme-based bioremediation of wastewater is of high interest. These fungi produce considerable amounts of extracellular ligninolytic enzymes during solid-state fermentation on lignocellulosic materials such as straw and sawdust..

Oyster Mushroom · 2024 · Journal Article · Environmental science and pollution research international

Utilization of agricultural residues for energy and resource recovery towards a sustainable environment.

Fungal pre-treatment using Pleurotus ostreatus (PO) was carried out on individual and combinations of agro-waste wheat straw (WS), rice straw (RS), and pearl millet straw (PMS) with the addition of biochar (5%,7.5% and 10%) to reduce the pre-treatment duration..

Reishi · 2023 · Review · International journal of biological macromolecules

Colorectal cancer inhibitory properties of polysaccharides and their molecular mechanisms: A review.

Colorectal cancer (CRC) is one of the three major malignant tumors in the world. The major treatments currently recommended for it are surgery, radiotherapy, and chemotherapy, all of which are frequently accompanied by a poor prognosis and high recurrence rate..

OncologyImmune supportMetabolic healthGut & microbiome

Reishi · 2023 · Review · Molecules (Basel, Switzerland)

Exploring Edible Mushrooms for Diabetes: Unveiling Their Role in Prevention and Treatment.

Diabetes mellitus is a complex illness in which the body does not create enough insulin to control blood glucose levels. Worldwide, this disease is life-threatening and requires low-cost, side-effect-free medicine.

Reishi · 2023 · Review · International journal of medicinal mushrooms

Exploring Mushroom Polysaccharides for the Development of Novel Prebiotics: A Review.

Prebiotics have gained much attention in recent years as functional food ingredients. This has encouraged researchers to look for sustainable alternative sources of prebiotics.

OncologyImmune supportMetabolic healthGut & microbiome

Reishi · 2023 · Review · International journal of biological macromolecules

Preclinical pharmacokinetics-related pharmacological effects of orally administered polysaccharides from traditional Chinese medicines: A review.

Polysaccharides (TCMPs) derived from traditional Chinese medicines (TCMs), such as Ganoderma lucidum, Astragalus membranaceus, Lycium barbarum, and Panax ginseng, are considered to be the main active constituents in TCMs..

Reishi · 2023 · Review · The American journal of Chinese medicine

Traditional Chinese Medicine in Osteoporosis Intervention and the Related Regulatory Mechanism of Gut Microbiome.

The gut microbiome (GM) has become a crucial factor that can affect the progression of osteoporosis. A number of studies have demonstrated the impact of Traditional Chinese Medicine (TCM) on GM and bone metabolism..

Almond Mushroom · 2022 · Preprint · journal metadata

Modelling of tuna around fish aggregating devices: the importance of ocean flow and prey

Catch and distribution of tuna in the ocean are typically investigated with ocean basin-scale models. Due to their large scale, such models must greatly simplify tuna behaviour occurring at a scale below ∼100 km, despite interactions at this level potentially being important to both catch and distribution of tuna..

Cognition & nervesGut & microbiome

Almond Mushroom · 2021 · Preprint · journal metadata

Investigating the growth of an engineered strain of Cyanobacteria with an Agent-Based Model and a Recurrent Neural Network

A computational framework combining Agent-Based Models (ABMs) and Deep Learning techniques was developed to help design microbial communities that convert light and CO 2 into useful bioproducts..

OncologyEnergy & fatigueMetabolic healthGut & microbiome

Chaga · 2020 · Journal Article · Journal of food science

Antioxidant, α-amylase and α-glucosidase activity of various solvent fractions of I. obliquus and the preventive role of active fraction against H2 O2 induced damage in hepatic L02 cells as fungisome.

Inonotus obliquus is a traditional mushroom well known for its therapeutic value. In this study, various solvent fractions of I.

Oyster Mushroom · 2020 · Journal Article · Molecules (Basel, Switzerland)

Degradative Ability of Mushrooms Cultivated on Corn Silage Digestate.

The current management practice of digestate from biogas plants involves its use for land application as a fertilizer. Nevertheless, the inadequate handling of digestate may cause environmental risks due to losses of ammonia, methane and nitrous oxide..

Mesima · 2020 · Journal Article · Journal of medicinal food

Dietary Mixed Cereal Grains Ameliorate the Azoxymethane and Dextran Sodium Sulfate-Induced Colonic Carcinogenesis in C57BL/6J Mice.

The chemopreventive effects of various mixed cereal grain (MCG) samples on azoxymethane (AOM, 10 mg/kg) and dextran sulfate sodium (DSS, 0.02 g/mL)-induced colorectal cancer (CRC) in C57BL/6J mice were studied..

Lion's Mane · 2019 · Journal Article · Journal of cereal science

Effects of solid-state fungi fermentation on phenolic content, antioxidant properties and fiber composition of lime cooked maize by-product (nejayote)

Free forms of phenolic compounds are more rapidly absorbed in the small intestine and distributed throughout the body. In nejayote, 85% of total phenolic content are found in bound forms..

Niu-Chang-Chih · 2014 · Randomized Controlled Trial · Nutrition research (New York, N.Y.)

Effectiveness of a novel herbal agent MB-6 as a potential adjunct to 5-fluoracil-based chemotherapy in colorectal cancer.

Natural products, such as fermented soybeans, have been used to treat various physical conditions, including cancer. MB-6 is a botanical preparation composed of fermented soybean extract, green tea extract, Antrodia camphorata mycelia, spirulina, grape seed extract, and curcumin extract..

OncologyGut & microbiome

Chaga · 2007 · Research Support, Non U.S. Gov'T · BioFactors (Oxford, England)

Chaga mushroom extract inhibits oxidative DNA damage in lymphocytes of patients with inflammatory bowel disease.

Inflammatory Bowel Disease (IBD) is partly caused by oxidative stress from free radicals and reduced antioxidant levels. Using hydrogen peroxide to induce oxidative stress in vitro in peripheral lymphocytes we investigated the induction of DNA damage supplemented with ethanolic extract of Chaga mushroom as a….

Immune supportMetabolic healthGut & microbiomeLiver support

Cordyceps · 2024 · Research Support, Non U.S. Gov'T · Molecular nutrition & food research

Tolypocladium sinense Mycelium Polysaccharide Alleviates Obesity, Lipid Metabolism Disorder, and Inflammation Caused by High Fat Diet via Improving Intestinal Barrier and Modulating Gut Microbiota.

SCOPE: Tolypocladium sinense is a fungus isolated from Cordyceps. Cordyceps has some medicinal value and is also a daily health care product.

Maitake · 2023 · Research Article · Microorganisms

Attributes of Culture Bacteria as Influenced by Ingredients That Help Treat Leaky Gut.

Consumers are becoming aware of functional ingredients such as medicinal herbs, polyphenols, mushrooms, amino acids, proteins, and probiotics more than ever before..

Gut & microbiomeLiver support

Almond Mushroom · 2023 · Journal Article · Journal of agricultural and food chemistry

Enzyme-Responsive Lignin Nanocarriers for Triggered Delivery of Abamectin to Control Plant Root-Knot Nematodes (Meloidogyne incognita).

Intelligently responsive nanoparticles can improve insecticidal activity against target organisms and reduce the use of pesticides in agriculture. In this study, enzymatic hydrolysis lignin (EHL) nanocarriers with enzyme responsiveness were successfully prepared by electrostatic interaction, and abamectin (Abm)-loaded….

Maitake · 2023 · Research Article · Pharmaceuticals (Basel, Switzerland)

Influences of Yogurt with Functional Ingredients from Various Sources That Help Treat Leaky Gut on Intestinal Barrier Dysfunction in Caco-2 Cells.

The impact of yogurts made with starter culture bacteria (L. bulgaricus and S.

Maitake · 2023 · Journal Article · Journal of dairy science

Physico-chemical, microbiological, and sensory characteristics of yogurt as affected by various ingredients.

l-Glutamine, quercetin, slippery elm bark, marshmallow root, N-acetyl-d-glucosamine, licorice root, maitake mushrooms, and zinc orotate have been reported to help treat leaky gut..

Cordyceps · 2023 · Research Article · Molecules (Basel, Switzerland)

Polysaccharides from Paecilomyces hepiali Prevent Acute Colitis in Association with Modulating Gut Microbiota and Treg/Th17 Immune Balance in Mice.

Cordyceps exopolysaccharide (CEP) has shown emerging potential in adjustment of gut microbiota and immune cell function. In this study, a water-soluble CEP with a molecular weight of 58.14 kDa was extracted from the fermentation broth of Paecilomyces hepiali, an endophytic fungus of Cordyceps sinensis..

Almond Mushroom · 2023 · Research Article · PloS one

Validating agent-based simulation model of hospital-associated Clostridioides difficile infection using primary hospital data.

As agent-based models (ABMs) are increasingly used for modeling infectious diseases, model validation is becoming more crucial. In this study, we present an alternate approach to validating hospital ABMs that focuses on replicating hospital-specific conditions and proposes a new metric for validating the….