MycoData

Cordyceps cicadae (C. cicadae), a species widely used in traditional Chinese medicine, belongs to the family Cordycepsaceae (order Hypocreales, class Ascomycota).

Metabolic health

Medium relevance

Cordyceps · 2026 · Research Article · Genes

Transcriptomic Insights into the Molecular Responses of Red Imported Fire Ants (Solenopsis invicta) to Beta-Cypermethrin and Cordyceps cicadae.

BACKGROUND: Solenopsis invicta, commonly known as the red imported fire ant (RIFA), is an important global invasive pest, and its management is challenging because of insecticide resistance and environmental problems. METHODS: In this research, we applied transcriptomics to analyze the molecular responses of S..

Immune supportCognition & nervesMetabolic health

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Oyster Mushroom · 2025 · Research Article · Foods (Basel, Switzerland)

(1→3)-α-d-Glucan from the Pink Oyster Mushroom (Pleurotus djamor): Structural Features.

(1→3)-α-d-Glucan is an important component of the cell wall of most fungi. The polymer has many applications, including as a therapeutic agent in the prevention or treatment of various diseases, as well as a heavy metal sorbent and a component of new materials used in the plastics industry..

Immune supportMetabolic health

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Nameko · 2025 · Journal Article · Natural product research

A novel polysaccharide from Pholiota nameko (T. Itô) S. Ito & S. Imai residue: chemical structure and hypoglycaemic activity in vitro.

A novel polysaccharide (APNP) with a molecular weight of 3.56 × 103 KDa and a total sugar content of 92.35 ± 0.07% was isolated from Pholiota nameko (T. Itô) S.

Immune supportMetabolic health

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Cordyceps · 2025 · Research Article · Journal of fungi (Basel, Switzerland)

Co-Culture with Two Soil Fungal Strains Enhances Growth and Secondary Metabolite Biosynthesis in Cordyceps takaomontana.

Cordyceps takaomontana is a medicinal fungus with significant pharmacological value, but how soil microbes promote its growth remains unclear. We established a solid-state co-culture system involving C.

Metabolic healthGut & microbiome

Medium relevance

Cordyceps · 2025 · Research Article · Metabolites

Effects of Cordyceps cicadae Polysaccharide on Gut Microbiota, the Intestinal Mucosal Barrier, and Inflammation in Diabetic Mice.

Background: Polysaccharides produced by the edible fungus Cordyceps cicadae can regulate blood sugar levels and may represent a suitable candidate for the treatment of diabetes and its complications. However, there is limited information available about the mechanism of how C..

Immune supportMetabolic healthGut & microbiome

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Oyster Mushroom · 2025 · Research Article · Scientific reports

Exploring natural AMPK activators from bioactive compounds in fenugreek and oyster mushroom for management of type 2 diabetes.

Oral antidiabetic drugs mainly act by stimulating pancreatic β-cells, but prolonged stimulation may lead to exhaustion and impaired insulin secretion. In contrast, AMP-activated protein kinase (AMPK) lowers blood glucose through an insulin-independent pathway, offering therapeutic potential..

Metabolic health

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Cordyceps · 2025 · Research Article · Journal of fungi (Basel, Switzerland)

Histopathological Study of Host-Pathogen Interactions Between Cordyceps javanica PSUC002 and Hypothenemus hampei.

The use of entomopathogenic fungi (EPF), such as Cordyceps javanica, to reduce insect pest populations is gaining traction since it is an environmentally safe approach that can control many pests at different life stages..

Energy & fatigueMetabolic health

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Cordyceps · 2025 · Journal Article · Journal of pharmaceutical and biomedical analysis

Integrating proteomics, metabolomics, and network pharmacology to investigate the mechanism of Cordyceps sinensis in the treatment of COPD rats.

Chronic obstructive pulmonary disease (COPD) causes significant morbidity and mortality, ranking as the third leading cause of death globally. Cordyceps sinensis (C..

Immune supportMetabolic healthRespiratory

Medium relevance

Cordyceps · 2025 · Journal Article · Carbohydrate polymers

Metabolic outcomes of Cordyceps fungus and Goji plant polysaccharides during in vitro human fecal fermentation.

This study was to assess the digestion and colonic fermentation of two bioactive polysaccharides, EPS-LM and LBPS, and the subsequent influences on human gut microbiota through simulated gastrointestinal systems..

Immune supportMetabolic healthGut & microbiome

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Oyster Mushroom · 2025 · Journal Article · International journal of medicinal mushrooms

Microencapsulation of Abalone Oyster Mushroom Pleurotus cystidiosus (Agaricomycetes): Antidiabetic, and Anti-Inflammatory Activity in Streptozotocin-Induced Diabetic Rat Model.

Pleurotus cystidiosus (abalone oyster mushroom) is an edible species that belongs to the group of woody mushrooms from the Pleurotaceae family. This mushroom contains bioactive compounds such as alkaloids, flavonoids, polyphenols, rutin, quercetin, and triterpenoids that act as antidiabetics and anti-inflammatory….

Immune supportMetabolic health

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Cordyceps · 2025 · Research Article · Journal of fungi (Basel, Switzerland)

Optimization of Protoplast Preparation and Establishment of PEG-Mediated Genetic Transformation Method in Cordyceps cicadae.

Cordyceps cicadae (C. cicadae) is an important edible medicinal fungus; however, owing to its wild growth and lack of genome annotation, construction of a stable genetic transformation system in C.

Metabolic health

Medium relevance

Oyster Mushroom · 2025 · Research Article · Animal nutrition (Zhongguo xu mu shou yi xue hui)

Oyster mushroom fermented Vachellia erioloba pods as replacement for wheat bran in broiler diets: Physiology and meat physicochemical and nutritional quality.

High feed costs and compromised meat quality are among the major issues perturbing the global broiler industry. This study therefore investigated Vachellia erioloba pods-derived oyster mushroom spent substrate (OMSS) as a potential nutraceutical feed ingredient to replace wheat bran for enhancing meat quality in….

Immune supportEnergy & fatigueMetabolic health

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Cordyceps · 2025 · Research Article · Frontiers in medicine

Preventing metabolic-associated fatty liver disease with fermented cordyceps preparation: an electronic medical record based study.

BACKGROUND: Metabolic-associated fatty liver disease (MAFLD) is a prevalent chronic liver condition with significant health implications. Fermented Cordyceps Preparation (FCP) has shown promise in managing metabolic disorders, prompting interest in its potential for MAFLD prevention..

Metabolic healthLiver support

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Cordyceps · 2025 · Journal Article · Natural product research

The synergistic effect of Cordyceps sinensis and Gymnema inodorum (Lour.) Decne. extracts on amelioration of glucose intolerance and dyslipidemia in high-fat diet-fed mice.

Cordyceps sinensis (C. sinensis) and Gymnema inodorum (Lour.) Decne.

Metabolic health

Medium relevance

Cordyceps · 2025 · Journal Article · Journal of Asian natural products research

Therapeutic potential of Cordyceps sinensis targeting oxidative stress and inflammatory response in the treatment of COPD rats: insights from metabolomics analysis.

This study aimed to investigate the effects of wild Cordyceps sinensis on chronic obstructive pulmonary disease (COPD) rats through metabolomics approach, combined with biochemical parameters evaluations. Consequently, C.

Immune supportMetabolic healthRespiratory

Medium relevance

Cordyceps · 2024 · Research Article · Chinese herbal medicines

Chemical components in cultivated Cordyceps sinensis and their effects on fibrosis.

OBJECTIVE: Cultivated Cordyceps sinensis powder has been used as clinical drug and healthy food to nourish the lung and kidney, which solves the problem of serious shortage of wild C. sinensis.

Immune supportEnergy & fatigueMetabolic healthSkin & hydration

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Oyster Mushroom · 2024 · Research Article · Scientific reports

Dietary oyster mushroom fermented Vachellia erioloba pods enhance Boschveld chicken meat healthiness without altering its physicochemical quality, growth performance and physiology.

The high content of fibre and antinutritional phytochemicals limit the utilization of Vachellia erioloba tree pods as nutraceutical feed additive for indigenous chicken diets..

Energy & fatigueMetabolic health

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Cordyceps · 2024 · Research Article · Journal of fungi (Basel, Switzerland)

Evaluation of Cordyceps sinensis Quality in 15 Production Areas Using Metabolomics and the Membership Function Method.

Cordyceps sinensis is a precious medicinal and edible fungus, which is widely used in body health care and disease prevention. The current research focuses on the comparison of metabolite characteristics between a small number of samples and lacks a comprehensive evaluation of the quality of C..

Energy & fatigueMetabolic health

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Cordyceps · 2024 · Research Article · Insects

Histopathological Alterations in Nilaparvata lugens (Hemiptera: Delphacidae) after Exposure to Cordyceps javanica.

The brown planthopper (BPH), Nilaparvata lugens (Stål, 1854), is a pest of rice plants worldwide. Cordyceps javanica is a destructive entomopathogenic fungus known to attack leafhoppers or BPHs specifically.

Metabolic health

Medium relevance

Cordyceps · 2024 · Journal Article · Carbohydrate polymers

Metabolic outcomes of Cordyceps fungus and Goji plant polysaccharides during in vitro human fecal fermentation

Immune supportMetabolic healthGut & microbiome

Medium relevance

Cordyceps · 2024 · Journal Article · Fungal biology

Metabolome and transcriptome unveil the mechanism of light on regulating beauvericin synthesis in Cordyceps chanhua.

Cordyceps chanhua, an important cordycipitoid medical mushroom with wide use in Asia, has gained attention for its bioactive component beauvericin (BEA), which is of medicinal value as a drug lead, but also of food safety risk. Recent observations by our group revealed a significant decrease of BEA content in C..

Metabolic health

Medium relevance

Cordyceps · 2024 · Journal Article · Journal of ethnopharmacology

Multi-omics reveals the testosterone promotion effect mechanism of Cordyceps Sobolifera on Leydig cells.

ETHNOPHARMACOLOGICAL RELEVANCE: Cordyceps sobolifera (CS) has been traditionally utilized as an ethnic remedy for various health conditions, including chronic kidney diseases, anti-fatigue interventions, and management of chronic inflammation..

Immune supportEnergy & fatigueMetabolic health

Medium relevance

Oyster Mushroom · 2024 · Journal Article · Food & function

Novel approach for ameliorating high-fat diet-induced syndromes via probiotic-fermented oyster mushroom: from metabolites and microbiota to regulation mechanisms.

The potential effects of probiotics on lowering lipid accumulation and alleviating gut microbiota perturbation have been extensively substantiated, but whether Lactobacillus rhamnoses-fermented oyster mushroom (FOM) could more pronouncedly attenuate obesity remains unclear..

OncologyMetabolic healthGut & microbiomeLiver support

Medium relevance

Nameko · 2024 · Journal Article · Journal of environmental management

Performance of co-composting Pholiota nameko spent mushroom substrate and pig manure at different proportions: Chemical properties and humification process.

Co-composting is the controlled aerobic degradation of organics, using more than one feedstock. By combining the spent mushroom substrate of Pholiota nameko (SMS) and pig manure (PM), the benefits of each could be used to optimize the composting process and the final product..

Immune supportEnergy & fatigueMetabolic health

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Cordyceps · 2024 · Research Article · International journal of molecular sciences

RNA-Seq-Based Transcriptome Analysis of Chinese Cordyceps Aqueous Extracts Protective Effect against Adriamycin-Induced mpc5 Cell Injury.

Pharmacogenomic analysis based on drug transcriptome characteristics is widely used to identify mechanisms of action. The purpose of this study was to elucidate the molecular mechanism of protective effect against adriamycin (ADM)-induced mpc5 cell injury of Chinese cordyceps aqueous extracts (WCCs) by a systematic….

Immune supportEnergy & fatigueMetabolic health

Medium relevance

Cordyceps · 2024 · Journal Article · Pesticide biochemistry and physiology

Secondary metabolites in Cordyceps javanica with insecticidal potential.

Cordyceps javanica has been registered as a fungal insecticide in several countries. However, little is known about whether metabolic toxins are involved in the insecticidal process.

Metabolic health

Medium relevance

Cordyceps · 2024 · Journal Article · International journal of biological macromolecules

The "crosstalk" between gut microbiota, metabolites and genes in diet-induced hepatic steatosis mice intervened with Cordyceps guangdongensis polysaccharides.

Cordyceps guangdongensis, a novel edible mushroom in China, has shown many positive health effects. In this study, we extracted the C.

Immune supportMetabolic healthGut & microbiomeLiver support

Medium relevance

Cordyceps · 2024 · Journal Article · Analytical and bioanalytical chemistry

Tissue distribution of metabolites in Cordyceps cicadae determined by DESI-MSI analysis.

In this paper, we establish an in situ visualization analysis method to image the spatial distribution of metabolites in different parts (sclerotium, coremium) and different microregions of Cordyceps cicadae (C..

Immune supportMetabolic health

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Cordyceps · 2024 · Journal Article · The Journal of pharmacy and pharmacology

Wild Cordyceps proteins reinforce intestinal epithelial barrier through MAPK/NF-κB pathway in MRL/lpr mice.

OBJECTIVES: The effects of wild Cordyceps proteins (WCPs) on the gut microbiota and the immune system of MRL/lpr mice were studied. METHODS: The effects of WCP on serum metabolic indexes (total triglyceride, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol) content was….

OncologyImmune supportMetabolic healthGut & microbiome

Medium relevance

Maitake · 2020 · Journal Article · International journal of biological macromolecules

Purification, isolation, and structure characterization of water soluble and insoluble polysaccharides from Maitake fruiting body.

The crude polysaccharides (GFP) were isolated from the Maitake fruiting body (Grifola frondosa) and purified by DEAE Cellulose-52 ionic-exchange chromatography and Sephadex G-25 gel filtration chromatography in that order. Five main fractions, GFP-1 to GFP-5 were obtained through the isolation and purification steps..

Immune supportMetabolic health

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Shiitake · 2020 · Journal Article · International journal of medicinal mushrooms

Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes): Absence of Changes in Maternal Reproductive Performance and Embryofetal Development In Vivo.

The shiitake culinary-medicinal mushroom Lentinus edodes (=Lentinula edodes) has been used as a nutritional complement. This study evaluated, through reprotox tests, the consumption of L.

Energy & fatigueMetabolic health

Medium relevance

Maitake · 1987 · Journal Article · Journal of nutritional science and vitaminology

Effect of Shiitake (Lentinus edodes) and Maitake (Grjfola frondosa) Mushrooms on Blood Pressure and Plasma Lipids of Spontaneously Hypertensive Rats

To study the effect of Shiitake (Lentinus edodes) and Maitake (Grifola frondosa) on hypertension, spontaneously hypertensive rats (SHR) were fed a diet containing 5% mushroom powder and 0.5% NaCl solution as drinking water for 9 weeks. The dietary mushrooms decreased the blood pressure..

Metabolic health

Medium relevance

King Oyster · 2026 · Review · Pharmaceuticals (Basel, Switzerland)

The Significance of a Mushroom Diet in the Prevention of Osteoporosis.

Osteoporosis is a metabolic disease of the skeleton characterized by a low bone mass and deterioration of bone tissue structure, leading to increased fragility and susceptibility to fractures. It is often referred to as the "silent killer of bones" because it progresses without symptoms until a bone fracture occurs..

Metabolic healthGut & microbiome

Medium relevance

King Oyster · 2025 · Review · Applied microbiology and biotechnology

Aryl-alcohol oxidases: catalysis, diversity, structure-function and emerging biotechnological applications.

Aryl-alcohol oxidases (AAOs) are flavin-dependent enzymes of the glucose-methanol-choline (GMC) oxidoreductase superfamily that catalyze the oxidation of a broad range of activated primary alcohols into their corresponding aldehydes, generating hydrogen peroxide..

Metabolic health

Medium relevance

Cordyceps · 2025 · Review · Molecules (Basel, Switzerland)

Fungal Polysaccharides as Modulators of Molecular Pathways in Liver Health.

Fungal polysaccharides represent a structurally diverse group of bioactive compounds with increasing recognition for their hepatoprotective potential. This review synthesizes current evidence on their roles in the prevention and treatment of liver diseases, including alcohol-related liver disease (ALD), metabolic….

Immune supportCognition & nervesMetabolic healthGut & microbiome

Medium relevance

Cordyceps · 2024 · Review · Frontiers in microbiology

Advances in biosynthesis and metabolic engineering strategies of cordycepin.

Cordyceps militaris, also called as bei-chong-cao, is an insect-pathogenic fungus from the Ascomycota phylum and the Clavicipitaceae family. It is a valuable filamentous fungus with medicinal and edible properties that has been utilized in traditional Chinese medicine (TCM) and as a nutritious food..

Metabolic health

Medium relevance

Reishi · 2023 · Abstract · Journal of animal science

202 Functional Properties of Ganoderma Lucidum (GL) Supplementation in Canine Nutrition

Metadata-grounded summary: This abstract indexes research on Ganoderma lucidum in Journal of animal science in 2023. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

OncologyImmune supportMetabolic healthLiver support

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Oyster Mushroom · 2023 · Abstract · Journal of animal science

347 Effects of Inoculation Period on the Nutritive Value of Pleurotus Ostreatus Treated Corn Stover

Metadata-grounded summary: This abstract indexes research on Pleurotus ostreatus in Journal of animal science in 2023. MycoData maps the paper to metabolic health based on its title, species context, article metadata, and study classification..

Metabolic health

Medium relevance

Snow Fungus · 2023 · Journal Article · Food chemistry

Acidic polysaccharides from black ear and silver ear mushrooms modulated the release and transport of glucose from gelatinised sorghum starch during digestion.

This study investigated the ability of acidic polysaccharides from Auricularia auricula-judae (AAP) and Tremella fuciformis (TFP) mushrooms to modulate starch digestion and absorption..

Immune supportMetabolic healthGut & microbiome

Medium relevance

Oyster Mushroom · 2023 · Published Erratum · Biology open

Correction: Molecular characterization and overexpression of mnp6 and vp3 from Pleurotus ostreatus revealed their involvement in biodegradation of cotton stalk lignin.

Metadata-grounded summary: This published erratum indexes research on Pleurotus ostreatus in Biology open in 2023. MycoData maps the paper to metabolic health based on its title, species context, article metadata, and study classification..

Metabolic health

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Oyster Mushroom · 2023 · Published Erratum · Doklady. Biochemistry and biophysics

Erratum to: Structure Analysis of the MatA Locus of Sexual Compatibility in the Edible Mushroom Pleurotus ostreatus.

Metadata-grounded summary: This published erratum indexes research on Pleurotus ostreatus in Doklady. Biochemistry and biophysics in 2023.

Metabolic health

Medium relevance

Shiitake · 2023 · Journal Article · Food research international (Ottawa, Ont.)

Shiitake polysaccharides acted as a non-competitive inhibitor to α-glucosidase and inhibited glucose transport of digested starch from Caco-2 cells monolayer.

The inhibition mechanism of shitake mushroom polysaccharides (Lentinula edodes polysaccharides, LEP) against α-glucosidase was studied by enzyme kinetic assay, fluorescence quenching and molecular docking..

Immune supportMetabolic healthGut & microbiome

Medium relevance

Niu-Chang-Chih · 2022 · Abstract · Current developments in nutrition

Antrodia Camphorata Supplement in the Early Life Inhibits Intestinal Tumorigenesis Later in Young Adult APC1638N Mice

Abstract Objectives Colorectal cancer (CRC) is a critical burden in the U.S. with a temporal increase in incidence in young adults.

OncologyImmune supportMetabolic healthGut & microbiome

Medium relevance

Niu-Chang-Chih · 2022 · Research Support, Non U.S. Gov'T · Microbiology spectrum

Sexual Crossing, Chromosome-Level Genome Sequences, and Comparative Genomic Analyses for the Medicinal Mushroom Taiwanofungus Camphoratus (Syn. Antrodia Cinnamomea, Antrodia Camphorata).

Taiwanofungus camphoratus mushrooms are a complementary and alternative medicine for hangovers, cancer, hypertension, obesity, diabetes, and inflammation. Though Taiwanofungus camphoratus has attracted considerable biotechnological and pharmacological attention, neither classical genetic nor genomic approaches have….

OncologyImmune supportMetabolic health

Medium relevance

Reishi · 2021 · Published Erratum · Frontiers in chemistry

Erratum: Meroterpenoids From Ganoderma lucidum Mushrooms and Their Biological Roles in Insulin Resistance and Triple-Negative Breast Cancer.

[This corrects the article DOI: 10.3389/fchem.2021.772740.]..

OncologyMetabolic health

Medium relevance

Maitake · 2015 · Research Support, Non U.S. Gov'T · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Experimental study on intervention effect of Grifola frondosa on nonalcoholic steatohepatitis].

To study the preventive effect of Grifola frondosa on nonalcoholic steatohepatitis (NASH). The rat model of NASH was established by feeding high-fat diets for 12 weeks and intervened with 0.5 g · kg(-1) · d(-1) and 1.0 g · kg(-1) · d(-1) of C.

Immune supportMetabolic healthLiver support

Medium relevance

Lion's Mane · 2015 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

A polysaccharide from cultured mycelium of Hericium erinaceus and its anti-chronic atrophic gastritis activity.

A polysaccharide named EP-1 was found by screening cultured mycelium of Hericium erinaceus, which was extracted and subjected to precipitation with ethanol, hollow-fiber ultrafiltration and ion-exchange chromatography..

Immune supportMetabolic health

Medium relevance

Enoki · 2015 · Research Support, Non U.S. Gov'T · Journal of microbiology and biotechnology

Characterization of β-glucosidase produced by the white rot fungus Flammulina velutipes.

β-Glucosidase production by the white rot fungus Flammulina velutipes CFK 3111 was evaluated using different carbon and nitrogen sources under submerged fermentation. Maximal extracellular enzyme production was 1.6 U/ml, corresponding to a culture grown in sucrose 40 g/l and asparagine 10 g/l..

Metabolic health

Medium relevance

Turkey Tail · 2015 · Research Support, Non U.S. Gov'T · Bioprocess and biosystems engineering

Chitosan multiple addition enhances laccase production from Trametes versicolor.

Chitosan multiple addition strategy was developed to improve laccase production from Trametes versicolor cultures. The optimized multiple addition strategy was carried out by two-time addition of 0.1 g L(-1) chitosan to a 2-day-old culture media, with 24-h interval between the treatments..

Energy & fatigueMetabolic health