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Immune supportCognition & nervesLiver support

Reishi · 2022 · Journal Article · Nutrients

Ganoderma Lucidum Triterpenoids Improve Maternal Separation-Induced Anxiety- and Depression-like Behaviors in Mice by Mitigating Inflammation in the Periphery and Brain.

Although early life stress (ELS) can increase susceptibility to adulthood psychiatric disorders and produce a greater inflammatory response in a stressful event, targeted preventive and therapeutic drugs still remain scarce..

OncologyImmune supportSkin & hydration

Lion's Mane · 2022 · Journal Article · International journal of biological macromolecules

Gastroprotective activity of polysaccharide from the fruiting body of Hericium erinaceus against acetic acid-induced gastric ulcer in rats and structure of one bioactive fraction.

This study aimed at investigating gastroprotective activity of Hericium erinaceus polysaccharide (HEP) and characterizing one of its bioactive fractions. Acetic acid-induced gastric ulcer (GU) rat model was used to evaluate the gastroprotective activity of HEP, while H2O2-induced injury GES-1 cell model was conducted….

Immune supportGut & microbiome

Chaga · 2022 · Research Article · Frontiers in veterinary science

Gender-related differences in the effects of Inonotus obliquus polysaccharide on intestinal microorganisms in SD rats model.

Natural edible fungal polysaccharides are of research and application value for the prevention of diseases by improving the microenvironment within the intestine..

OncologyImmune supportMetabolic health

Chaga · 2022 · Research Article · BMC genomics

Genome sequencing of Inonotus obliquus reveals insights into candidate genes involved in secondary metabolite biosynthesis.

BACKGROUND: Inonotus obliquus is an important edible and medicinal mushroom that was shown to have many pharmacological activities in preclinical trials, including anti-inflammatory, antitumor, immunomodulatory, and antioxidant effects..

Cordyceps · 2022 · Research Article · Mycology

Glyceroglycolipids from the solid culture of Ophiocordyceps sinensis strain LY34 isolated from Tibet of China.

Ophiocordyceps sinensis is a well-known entomogenous fungus with its fruiting bodies or cultural mycelium as food and herbal medicines in Asia. While metabolites which could responsible for its potent pharmaceutical effects has long remained to be elucidated..

OncologyImmune support

OncologyImmune supportEnergy & fatigueSkin & hydration

Maitake · 2022 · Research Article · Nutrients

Grifola frondosa Extract Containing Bioactive Components Blocks Skin Fibroblastic Inflammation and Cytotoxicity Caused by Endocrine Disrupting Chemical, Bisphenol A.

Grifola frondosa (GF), a species of Basidiomycotina, is widely distributed across Asia and has been used as an immunomodulatory, anti-bacterial, and anti-cancer agent..

Immune supportEnergy & fatigue

Maitake · 2022 · Research Article · Current research in food science

Grifolamine A, a novel bis-γ-butyrolactone from Grifola frondosa exerted inhibitory effect on α-glucosidase and their binding interaction: Affinity and molecular dynamics simulation.

A novel bis-γ-butyrolactone grifolamine A (1), the first γ-butyrolactone dimer from nature, together with three known γ-butyrolactones (2-4), was isolated from the byproduct from Grifola frondosa polysaccharides preparation process..

Immune supportEnergy & fatigueGut & microbiome

Oyster Mushroom · 2022 · Research Article · Animals: an open access journal from MDPI

Growth Performance and Hematological Changes in Growing Sika Deers Fed with Spent Mushroom Substrate of Pleurotus ostreatus.

The purpose of this experiment is to expand the feed of growing sika deer and to explore the effects on growing sika deer of the spent mushroom substrate of Pleurotus ostreatus (SMS-MP). Twelve immature female growing sika deer were randomly assigned to four groups..

Immune supportCognition & nervesMetabolic healthGut & microbiome

Lion's Mane · 2022 · Research Article · Journal of animal science and technology

Gut microbiota profiling in aged dogs after feeding pet food contained Hericium erinaceus.

Health concern of dogs is the most important issue for pet owners. People who have companied the dogs long-term provide the utmost cares for their well-being and healthy life.

Lion's Mane · 2022 · Research Article · Nutrients

Hericium erinaceus Mycelium Ameliorates In Vivo Progression of Osteoarthritis.

Osteoarthritis (OA) is an age-related disorder that affects the joints and causes functional disability. Hericium erinaceus is a large edible mushroom with several known medicinal functions.

OncologyImmune support

Immune supportMetabolic healthLiver support

Reishi · 2022 · Research Article · Metabolites

Hypouricemic Effect of Submerged Culture of Ganoderma lucidum in Potassium Oxonate-Induced Hyperuricemic Rats.

Hyperuricemia is a disease caused by a high level of uric acid in the blood. It is an important factor for gout and may be linked to renal and hepatic failure.

Maitake · 2022 · Research Article · Food science & nutrition

Immunostimulatory and antioxidant activities of the selenized polysaccharide from edible Grifola frondosa.

Grifola frondosa polysaccharide (GFP2) was extracted and purified by anion-exchange chromatography. A selenized G.

OncologyImmune supportMetabolic healthGut & microbiome

Mesima · 2022 · Research Article · Pharmaceuticals (Basel, Switzerland)

Immunostimulatory Effect of Postbiotics Prepared from Phellinus linteus Mycelial Submerged Culture via Activation of Spleen and Peyer's Patch in C3H/HeN Mice.

Medicinal mushrooms are an important natural resource promoting health benefits. Herein, Phellinus linteus mycelia were prepared under submerged cultivation, the mycelium-containing culture broth was extracted as a whole to obtain the postbiotic materials (PLME), and its effect on the immune system was evaluated in….

Shiitake · 2022 · Journal Article · Journal of bioscience and bioengineering

Improved production and antioxidant activity of exopolysaccharides by submerged culture of Lentinula edodes by the addition of lignocellulose.

The objective of this study was to investigate the effect of addition of four different lignocellulose (water-treated corn straw, water-treated xylosma sawdust, alkali-treated corn straw and alkali-treated xylosma sawdust) on the production and antioxidant activity of exopolysaccharides by Lentinula edodes..

Immune supportLiver supportRespiratory

Lion's Mane · 2022 · Research Article · Bioresources and bioprocessing

In vitro assessment of multipotential therapeutic importance of Hericium erinaceus mushroom extracts using different solvents.

Infectious disease is one of the major threats to humans and it is the second leading cause of death worldwide. Edible mushrooms have many nutritional and medicinal values to human health..

Reishi · 2022 · Research Article · Molecules (Basel, Switzerland)

Inhibition on α-Glucosidase Activity and Non-Enzymatic Glycation by an Anti-Oxidative Proteoglycan from Ganoderma lucidum.

The prevention of postprandial hyperglycemia and diabetic complications is crucial for diabetes management. Inhibition of α-glucosidase to slow carbohydrate metabolism is a strategy to alleviate postprandial hyperglycemia..

Immune supportMetabolic healthGut & microbiome

Snow Fungus · 2022 · Journal Article · Food Hydrocolloids

Interaction between potato starch and Tremella fuciformis polysaccharide

In order to elucidate the mechanism of interaction between Tremella fuciformis polysaccharide (TP) and potato starch (PS), PS-TP composites with different concentrations of TP were prepared, and their physicochemical properties, in vitro digestibility characteristic and microstructure were investigated..

Snow Fungus · 2022 · Journal Article · Journal of food processing and preservation

Investigation on the effects of drying methods on the structure and antioxidant activity of Tremella fuciformis polysaccharides using asymmetrical flow field‐flow fractionation

Polysaccharide is an important bioactive component in Tremella fuciformis (T. fuciformis).

OncologyImmune supportCognition & nerves

Reishi · 2022 · Journal Article · Phytochemistry

Lanostane triterpenoids from Ganoderma lucidum and their inhibitory effects against FAAH.

Ganoderma lucidum is a famous edible and medicinal fungus. Through a bioactive phytochemical investigation of the ethanolic extracts of the fruiting bodies of G.

Immune supportLiver support

Reishi · 2022 · Journal Article · Phytochemistry

Lanostane-type triterpenoids from the mycelial mat of Ganoderma lucidum and their hepatoprotective activities.

Ganoderma lucidum (G. lucidum), a well-known Polyporaceae family fungus, is valued for its edibility and medicinal properties.

OncologyImmune supportGut & microbiomeRespiratory

Shiitake · 2022 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Lentinula edodes extract increases goblet cell number and Muc2 expression in an intestinal inflammatory model of Trichinella spiralis infection.

AHCC® is a standardized extract of cultured mushroom (Lentinula edodes) mycelia with a wide variety of therapeutic effects including anti-inflammatory, antitumor and antiviral effects. Trichinellosis, a food-borne parasitic zoonosis is caused by the nematode Trichinella spp..

OncologyImmune supportMetabolic healthGut & microbiome

Shiitake · 2022 · Journal Article · Arquivos de gastroenterologia

LENTINULA EDODES POLYSACCHARIDES SUPPRESSED PRO-INFLAMMATORY CYTOKINES EXPRESSION AND COLITIS IN MICE.

BACKGROUND: Polysaccharides from edible mushrooms possess immunomodulatory, anti-inflammatory, and anti-tumor activities. Recent studies indicated that necroptosis plays a role in the pathogenesis of inflammatory diseases and mediates increased expression of inflammatory cytokines..

Shiitake · 2022 · Research Article · Antioxidants (Basel, Switzerland)

Lentinula edodes, a Novel Source of Polysaccharides with Antioxidant Power.

The fruiting bodies of edible mushrooms represent an important source of biologically active polysaccharides. In this study, Lentinula edodes crude polysaccharides (LECP) were extracted in hot water, and their antioxidant and antiradical activities were investigated..

Reishi · 2022 · Journal Article · International journal of biological macromolecules

Microwave-assisted degradation of β-D-glucan from Ganoderma lucidum and the structural and immunoregulatory properties of oligosaccharide fractions.

Microwave-assisted degradation of β-(1 → 3,1 → 6)-D-glucan from Ganoderma lucidum and correlated immunoregulatory activities were investigated in this study. The optimal temperature and degradation time for microwave hydrothermal hydrolysis were 140 °C and 40 min, respectively..

Snow Fungus · 2022 · Journal Article · Food research international (Ottawa, Ont.)

Moisture and caking resistant Tremella fuciformis polysaccharides microcapsules with hypoglycemic activity

Tremella fuciformis polysaccharides (TPs) have attracted extensive attention as functional food constituents due to their bioactivity. However, β-D-glucan obtained from TPs is readily degraded by oxidation and easy to absorb water and agglomerate..

OncologyImmune supportMetabolic healthGut & microbiome

Yellow Morel · 2022 · Research Article · Frontiers in nutrition

Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model.

Type 2 diabetes mellitus (T2DM) is a health issue that causes serious worldwide economic problems. It has previously been reported that natural polysaccharides have been studied with regard to regulating the gut microbiota, which plays an important role in T2DM..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Yellow Morel · 2022 · Research Article · AMB Express

Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota.

Edible mushrooms have now been suggested as promising sources of biological functional ingredients and are the subject of the most recent nutrition research and novel functional foods. Polysaccharides from mushrooms exhibit impressive biological effects, notably against obesity..

OncologyImmune supportMetabolic healthLiver support

Yellow Morel · 2022 · Journal Article · Food research international (Ottawa, Ont.)

Mycochemical profile and health-promoting effects of morel mushroom Morchella esculenta (L.) – A review

Mushrooms have been well known for centuries in traditional Chinese medicine for their medicinal properties. Morchella esculenta (L.) Pers.

Maitake · 2022 · Journal Article · Trends in food science & technology

New light on Grifola frondosa polysaccharides as biological response modifiers

Grifola frondosa is a valuable fungus with high health and medicinal value, and it plays an important role in the treatment of diseases as traditional Chinese medicine. Among them, the active ingredient that plays the main function was polysaccharides..

OncologyImmune supportEnergy & fatigueMetabolic health

Yellow Morel · 2022 · Research Article · Foods (Basel, Switzerland)

Nutrition Profile and Animal-Tested Safety of Morchella esculenta Mycelia Produced by Fermentation in Bioreactors.

Morchella esculenta (ME), or "true" morel mushrooms, are one of the most expensive mushrooms. M.

Immune supportEnergy & fatigueMetabolic health

Enoki · 2022 · Journal Article · Industrial crops and products

Optimization of ultrasonic extraction of polysaccharides from Flammulina velutipes residue and its protective effect against heavy metal toxicity

The extraction process of polysaccharides from Flammulina velutipes residue (FVRP) was optimized by the single factor test and response surface methodology with the physical and chemical properties of FVRP determined..

Immune supportMetabolic healthGut & microbiomeLiver support

Reishi · 2022 · Journal Article · International journal of biological macromolecules

Organic chromium derived from the chelation of Ganoderma lucidum polysaccharide and chromium (III) alleviates metabolic syndromes and intestinal microbiota dysbiosis induced by high-fat and high-fructose diet.

Organic chromium is of great interest and has become an important chromium supplement resource in recent years because of its low toxicity and easy absorption. In our previous study, we synthesized a novel organic chromium [GLP-Cr] through the chelation of Ganoderma lucidum polysaccharide and chromium (III)..

Immune supportGut & microbiome

Snow Fungus · 2022 · Journal Article · International journal of biological macromolecules

Physicochemical properties and in vitro digestion behavior of a new bioactive Tremella fuciformis gum.

A new easy-dissolved Tremella fuciformis gum (TFG) from fruiting body was investigated in detail from three aspects: physicochemical characteristics, rheological behavior and in vitro digestion behavior..

OncologyImmune supportSkin & hydration

Zhu Ling · 2022 · Journal Article · Phytomedicine: international journal of phytotherapy and phytopharmacology

Phytochemistry and bioactivities of the main constituents of Polyporus umbellatus (Pers.) Fries.

BACKGROUND: Edible fungi resources have good application prospects in the research and development of food, medicine, and health products. Polyporus umbellatus (Pers.) Fries, as a precious edible and medicinal fungus, has long been used by Chinese medicine to treat urinary systems and related kidney diseases..

Immune supportMetabolic healthGut & microbiomeLiver support

Oyster Mushroom · 2022 · Research Article · Nutrients

Pleurotus Ostreatus Ameliorates Obesity by Modulating the Gut Microbiota in Obese Mice Induced by High-Fat Diet.

Pleurotus ostreatus (PO), a common edible mushroom, contains rich nutritional components with medicinal properties. To explore the effect of PO on ameliorating obesity and modulating the gut microbiota, we administered the mice with a low-fat diet or high-fat diet containing different dosages of PO (mass fraction: 0%,….

Immune supportCognition & nervesEnergy & fatigue

Reishi · 2022 · Journal Article · Food & function

Polysaccharide from Ganoderma lucidum alleviates cognitive impairment in a mouse model of chronic cerebral hypoperfusion by regulating CD4+CD25+Foxp3+ regulatory T cells.

Ganoderma lucidum (G. lucidum) is a kind of edible and medicinal mushroom.

Immune supportMetabolic healthLiver support

Maitake · 2022 · Journal Article · The Journal of pharmacy and pharmacology

Polysaccharides of Grifola frondosa ameliorate oxidative stress and hypercholesterolaemia in hamsters fed a high-fat, high-cholesterol diet.

OBJECTIVES: This study was to evaluate the antioxidant and anti-hypercholesterolaemia activities of Grifola frondosa in hamsters fed a high-fat, high-cholesterol (HFHC) diet. METHODS: G..

Immune supportEnergy & fatigue

Maitake · 2022 · Journal Article · Journal of the science of food and agriculture

Purification and characterization of Se-enriched Grifola frondosa glycoprotein, and evaluating its amelioration effect on As3+ -induced immune toxicity.

BACKGROUND: Selenium (Se)-enriched glycoproteins have been a research highlight for the role of both Se and glycoproteins in immunoregulation. Arsenic (As) is a toxicant that is potentially toxic to the immune function and consequently to human health..

Immune supportEnergy & fatigue

Maitake · 2022 · Journal Article · Journal of the science of food and agriculture

Purification and characterization of Se‐enriched Grifola frondosa glycoprotein, and evaluating its amelioration effect on As3+‐induced immune toxicity

BACKGROUND: Selenium (Se)‐enriched glycoproteins have been a research highlight for the role of both Se and glycoproteins in immunoregulation. Arsenic (As) is a toxicant that is potentially toxic to the immune function and consequently to human health..

Mesima · 2022 · Journal Article · Preparative biochemistry & biotechnology

Purification of polysaccharides from Phellinus linteus by using an aqueous two-phase system and evaluation of the physicochemical and antioxidant properties of polysaccharides in vitro.

In this study, Phellinus linteus polysaccharides (PLPS) and proteins were simultaneously separated from P. linteus mycelia by using an aqueous two-phase system (ATPS) based on choline chloride ([Chol]Cl)/K2HPO4, and the physicochemical and antioxidant properties of PLPS after ATPS extraction were evaluated..

OncologyImmune supportGut & microbiomeLiver support

Reishi · 2022 · Research Article · Frontiers in nutrition

Removing the sporoderm from the sporoderm-broken spores of Ganoderma lucidum improves the anticancer and immune-regulatory activity of the water-soluble polysaccharide.

Plant-derived polysaccharides have demonstrated promising anti-cancer effects via immune-regulatory activity. The aim of the current study was to compare the chemical property and the anticancer effects of polysaccharides extracted from the sporoderm-removed spores of the medicinal mushroom Ganoderma lucidum (RSGLP),….

Immune supportCognition & nervesEnergy & fatigueSkin & hydration

Lion's Mane · 2022 · Research Article · Nutrients

Searching for a Longevity Food, We Bump into Hericium erinaceus Primordium Rich in Ergothioneine: The "Longevity Vitamin" Improves Locomotor Performances during Aging.

Phenotypic frailty is characterized by a progressive decline in physical functioning. During ageing, morphological and functional alterations involve the brain, and chief theories involve oxidative stress, free radical accumulation, and reduced antioxidant defenses as the most implicated mechanisms..

Immune supportLiver support

Reishi · 2022 · Journal Article · Ecotoxicology and environmental safety

Sporoderm-broken spores of Ganoderma lucidum alleviates liver injury induced by DBP and BaP co-exposure in rat.

Dibutyl phthalate (DBP) and Benzo(a)pyrene (BaP) are ubiquitous contaminants in environment and foodstuffs, which increase the chance of their combined exposure to humans in daily life. However, the combined effects of DBP and BaP on liver and the underlying mechanisms are still unclear..

Niu-Chang-Chih · 2022 · Research Article · Frontiers in microbiology

Structural and Potential Functional Properties of Alkali-Extracted Dietary Fiber From Antrodia camphorata.

Antrodia camphorata is rich in a variety of bioactive ingredients; however, the utilization efficiency of the residue of A. camphorata is low, resulting in serious waste.

Immune supportLiver support

Reishi · 2022 · Research Article · Food chemistry: X

Structural characterization and hepatoprotective activity of an acidic polysaccharide from Ganoderma lucidum.

In this study, Ganoderma lucidum crude polysaccharide (GLP) was found to have protective effect on liver damage in mice caused by restraint stress through improving oxidative status..

Immune supportSkin & hydration

Snow Fungus · 2022 · Journal Article · Food chemistry

Study on effects of preparation method on the structure and antioxidant activity of protein-Tremella fuciformis polysaccharide complexes by asymmetrical flow field-flow fractionation.

Oxidation is an essential biological process for human life. In this study, low density lipoprotein-Tremella fuciformis polysaccharide (LDL-TFP) complexes were prepared by electrostatic and covalent methods..

OncologyImmune supportMetabolic health

Lion's Mane · 2022 · Research Article · Current research in toxicology

Subchronic toxicity and genotoxicity studies of Hericium erinaceus β-glucan extract preparation.

The medicinal effects of Hericium erinaceus have been long documented in scientific studies of Eastern traditional medicine. It is widely consumed, because of its nutritional qualities and perceived health benefits.

Maitake · 2022 · Journal Article · Journal of food composition and analysis

Supercritical CO2 extraction, structural analysis and bioactivity of polysaccharide from Grifola frondosa

Polysaccharide was extracted from Grifola frondosa with supercritical CO₂ technology. The optimum extraction conditions for the highest yield were determined by Box-Behnken design: the pressure was 34.5Mpa, the extraction temperature was 36.7 ℃, the extraction time was 116.3 min and the ratio of entrainer to raw….

OncologyImmune support