MycoData

Emerging contaminants are a wide group of chemical products that are found at low concentrations in the environment. These contaminants can be either natural, e.g., estrogens, or synthetics, such as pesticides and pharmaceuticals, which can enter the environment through the water and sludge from wastewater treatment….

Metabolic health

Medium relevance

Chaga · 2015 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Effect of chemicals on production, composition and antioxidant activity of polysaccharides of Inonotus obliquus.

Polysaccharides are important secondary metabolites from the medicinal mushroom Inonotus obliquus. Various fatty acids, surfactants and organic solvents as cell membrane-reorganizing chemicals were investigated for their stimulatory effects on the growth of fungal mycelium and production of exopolysaccharides (EPS)….

Immune supportMetabolic health

Medium relevance

Maitake · 2015 · Research Support, Non U.S. Gov'T · Pharmaceutical biology

Effects of Grifola frondosa non-polar bioactive components on high-fat diet fed and streptozotocin-induced hyperglycemic mice.

CONTEXT: Consumption of medicinal mushrooms for disease prevention and maintaining health has a very long history in Asia. Grifola frondosa (Fr) S.F.

Immune supportCognition & nervesMetabolic health

Medium relevance

Niu-Chang-Chih · 2015 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Ergostatrien-3β-ol from Antrodia camphorata inhibits diabetes and hyperlipidemia in high-fat-diet treated mice via regulation of hepatic related genes, glucose transporter 4, and AMP-activated protein kinase phosphorylation.

This study was designed to explore the effects and mechanism of ergostatrien-3β-ol (EK100) from the submerged whole broth of Antrodia camphorata on diabetes and dyslipidemia in high fat diet (HFD)-fed mice for 12 weeks..

Energy & fatigueMetabolic healthLiver support

Medium relevance

Enoki · 2015 · Research Support, Non U.S. Gov'T · World journal of microbiology & biotechnology

Laccase production and metabolic diversity among Flammulina velutipes strains.

Twelve Flammulina velutipes strains originating from Poland were identified using internal transcribed spacer (ITS) region sequencing. Based on the sequences obtained, the genomic relationship of the analyzed strains was determined.

Energy & fatigueMetabolic health

Medium relevance

Lion's Mane · 2015 · Research Support, Non U.S. Gov'T · International journal of nanomedicine

Neurite outgrowth stimulatory effects of myco synthesized AuNPs from Hericium erinaceus (Bull.: Fr.) Pers. on pheochromocytoma (PC-12) cells.

BACKGROUND: Hericium erinaceus has been reported to have a wide range of medicinal properties such as stimulation of neurite outgrowth, promotion of functional recovery of axonotmetic peroneal nerve injury, antioxidant, antihypertensive, and antidiabetic properties..

Cognition & nervesEnergy & fatigueMetabolic health

Medium relevance

Turkey Tail · 2015 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Polysaccharides of Trametes versicolor Improve Bone Properties in Diabetic Rats.

This study investigates the effects of Trametes versicolor (L.:Fr.) Pilát (TVP, also known as Yunzhi) on bone properties in diabetic rats. Forty-five male Wistar rats (8 weeks old) were fed either a chow diet (control) or a high-fat diet throughout the study period of 28 days..

Immune supportMetabolic health

Medium relevance

Mesima · 2015 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Structural features and antitumor activity of a novel polysaccharide from alkaline extract of Phellinus linteus mycelia.

A novel high molecular weight polysaccharide (PL-N1) was isolated from alkaline extract of the cultured Phellinus linteus mycelia. The weight average molecular weight (Mw) of PL-N1 was estimated at 343,000kDa.

OncologyImmune supportMetabolic health

Medium relevance

Niu-Chang-Chih · 2015 · Research Support, Non U.S. Gov'T · BioMed research international

The Ethanolic Extract of Taiwanofungus camphoratus (Antrodia camphorata) Induces Cell Cycle Arrest and Enhances Cytotoxicity of Cisplatin and Doxorubicin on Human Hepatocellular Carcinoma Cells.

Taiwanofungus camphoratus (synonym Antrodia camphorata) is a widely used medicinal fungus in the folk medicine of Taiwan with several pharmacological features such as anti-inflammatory, liver protection, antihypertensive, and antioxidative activities. The ethanolic extract of T..

OncologyImmune supportMetabolic healthLiver support

Medium relevance

Enoki · 2014 · Research Support, Non U.S. Gov'T · Sheng wu gong cheng xue bao = Chinese journal of biotechnology

[Inducible and constitutive expression of fip-fve from Flammulina velutipes in Pichia pastoris GS115].

We transformed the fip-fve gene into Pichia pastoris GS115 for inducible and constitutive expression to obtain feasible bioactvie recombinant Fip-fve. The fip-fve gene was cloned from Flammulina velutipes fruting body by PCR and ligated to pPIC9 to construct inducible expression vector pPIC9-FIP-fve, and promotor pgap….

Metabolic healthGut & microbiome

Medium relevance

Lion's Mane · 2014 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Anticancer potential of Hericium erinaceus extracts against human gastrointestinal cancers.

ETHNOPHARMACOLOGICAL RELEVANCE: Hericium is a genus of mushrooms (fungus) in the Hericiaceae family. Hericium erinaceus (HE) has been used for the treatment of digestive diseases for over 2000 years in China..

OncologyImmune supportEnergy & fatigueMetabolic health

Medium relevance

Niu-Chang-Chih · 2014 · Comparative Study · Phytomedicine: international journal of phytotherapy and phytopharmacology

Comparison of solid-state-cultured and wood-cultured Antrodia camphorata in anti-inflammatory effects using NF-κB/luciferase inducible transgenic mice.

PURPOSE: Antrodia camphorata (AC), a highly valued polypore mushroom native only to Taiwan, has been traditionally used as a medicine for the treatment of food and drug intoxication, diarrhea, abdominal pain, hypertension, skin itching, and cancer..

OncologyImmune supportEnergy & fatigueMetabolic health

Medium relevance

Mesima · 2014 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Effect of extraction media on preliminary characterizations and antioxidant activities of Phellinus linteus polysaccharides.

Three partially purified polysaccharides were extracted from Phellinus linteus mycelia using hot water, 1% (NH4)2C2O4, and 1.25M NaOH/0.05% NaBH4, and the extracts were named PL-W, PL-A, and, PL-N respectively..

Immune supportMetabolic health

Medium relevance

Mesima · 2014 · Comparative Study · International journal of food sciences and nutrition

Effects of polysaccharide from fruiting bodies of Agaricus bisporus, Agaricus brasiliensis, and Phellinus linteus on alcoholic liver injury.

In the present study, the curative effects of crude polysaccharides (PSs) from mushrooms on the symptoms of alcoholic liver injury were investigated. PSs from Agaricus bisporus, Agaricus brasiliensis, and Phellinus linteus fruiting bodies were administered by gavage at levels of 100 mg per kg body weight per day for 7….

Immune supportEnergy & fatigueMetabolic healthLiver support

Medium relevance

Turkey Tail · 2014 · Research Support, Non U.S. Gov'T · Applied biochemistry and biotechnology

Image analysis technique as a tool to identify morphological changes in Trametes versicolor pellets according to exopolysaccharide or laccase production.

Image analysis technique was applied to identify morphological changes of pellets from white-rot fungus Trametes versicolor on agitated submerged cultures during the production of exopolysaccharide (EPS) or ligninolytic enzymes. Batch tests with four different experimental conditions were carried out..

Immune supportMetabolic health

Medium relevance

Chaga · 2014 · Research Support, Non U.S. Gov'T · Phytotherapy research: PTR

Insulin-sensitizing and beneficial lipid-metabolic effects of the water-soluble melanin complex extracted from Inonotus obliquus.

Inonotus obliquus has been traditionally used for treatment of metabolic diseases; however, the mechanism remains to be elucidated. In this study, we found that the water-soluble melanin complex extracted from I.

Metabolic healthSkin & hydration

Medium relevance

Niu-Chang-Chih · 2014 · Research Support, Non U.S. Gov'T · Journal of industrial microbiology & biotechnology

Integrated strategy of pH-shift and glucose feeding for enhanced production of bioactive Antrodin C in submerged fermentation of Antrodia camphorata.

Antrodin C is one of the most potent bioactive components produced by the medicinal mushroom Antrodia camphorata. However, almost all studies in this field have focused on the biological activity of Antrodin C and relatively rare information has been reported regarding the biosynthetic process of Antrodin C..

Metabolic health

Medium relevance

Mesima · 2014 · Research Support, Non U.S. Gov'T · Journal of food science

Isolation, purification, and structural features of a polysaccharide from Phellinus linteus and its hypoglycemic effect in alloxan-induced diabetic mice.

Phellinus linteus is a medicinal mushroom that has been used in Oriental countries for centuries for its antitumor, antioxidant, immunomodulatory, and biological activity on hyperglycemia. A water-soluble crude polysaccharide was extracted using hot water from P.

OncologyImmune supportMetabolic health

Medium relevance

Lion's Mane · 2014 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Optimization of enzyme-assisted extraction and characterization of polysaccharides from Hericium erinaceus.

The enzyme-assisted extraction (EAE) of polysaccharides from the fruits of Hericium erinaceus was studied. In this study, response surface methodology and the Box-Behnken design based on single-factor and orthogonal experiments were applied to optimize the EAE conditions..

Immune supportMetabolic health

Medium relevance

Chaga · 2014 · Research Support, Non U.S. Gov'T · International immunopharmacology

Polysaccharides from Inonotus obliquus sclerotia and cultured mycelia stimulate cytokine production of human peripheral blood mononuclear cells in vitro and their chemical characterization.

Inonotus obliquus is an edible and medicinal mushroom to treat many diseases. In the present study, polysaccharides and fractions were isolated and purified by DEAE-52 and Sephadex G-200 chromatography from I.

Immune supportMetabolic health

Medium relevance

Chaga · 2014 · Research Support, Non U.S. Gov'T · Journal of bioscience and bioengineering

Stimulated production of steroids in Inonotus obliquus by host factors from birch.

Steroids was considered as one of the bioactive components in Inonotus obliquus, while this kind of secondary metabolites are less accumulated in cultured mycelia. In this study, effect of extracts from bark and core of host-related species, birch (Betula platyphylla Suk.), on steroid production of I..

Energy & fatigueMetabolic health

Medium relevance

Mesima · 2013 · Research Support, Non U.S. Gov'T · Chemico-biological interactions

Activation of P27kip1-cyclin D1/E-CDK2 pathway by polysaccharide from Phellinus linteus leads to S-phase arrest in HT-29 cells.

Our previous study showed that polysaccharide (P1) from Phellinus linteus exhibits a significant inhibitive activity on human colorectal carcinoma cells (HT-29). However its novel molecular mechanism remains unknown..

OncologyImmune supportMetabolic healthLiver support

Medium relevance

Niu-Chang-Chih · 2013 · Research Support, Non U.S. Gov'T · Journal of medicinal food

Antrodia camphorata grown on germinated brown rice inhibits HT-29 human colon carcinoma proliferation through inducing G0/G1 phase arrest and apoptosis by targeting the β-catenin signaling.

Antrodia camphorata (AC) has been used as a traditional medicine to treat food and drug intoxication, diarrhea, abdominal pain, hypertension, pruritis (skin itch), and liver cancer in East Asia..

OncologyEnergy & fatigueMetabolic healthGut & microbiome

Medium relevance

Chaga · 2013 · Research Support, Non U.S. Gov'T · Molecules (Basel, Switzerland)

Bioassay-guided isolation of DPP-4 inhibitory fractions from extracts of submerged cultured of Inonotus obliquus.

Inonotus obliquus is a medicinal mushroom used in Russian and Eastern European folk medicine for the treatment of gastrointestinal cancer, cardiovascular disease and diabetes. Previous studies in our laboratory have demonstrated that the mycelium powders of I..

OncologyMetabolic healthGut & microbiome

Medium relevance

Almond Mushroom · 2013 · Research Support, Non U.S. Gov'T · BioMed research international

Effects of an Agaricus blazei aqueous extract pretreatment on paracetamol-induced brain and liver injury in rats.

The action of an Agaricus blazei aqueous extract pretreatment on paracetamol injury in rats was examined not only in terms of the classical indicators (e.g., levels of hepatic enzymes in the plasma) but also in terms of functional and metabolic parameters (e.g., gluconeogenesis)..

Immune supportCognition & nervesMetabolic healthLiver support

Medium relevance

Enoki · 2013 · Research Support, Non U.S. Gov'T · Fungal biology

Ethanol production from high cellulose concentration by the basidiomycete fungus Flammulina velutipes.

Ethanol production by Flammulina velutipes from high substrate concentrations was evaluated. F.

Metabolic health

Medium relevance

Mesima · 2013 · Research Support, Non U.S. Gov'T · The American journal of Chinese medicine

Hispolon from Phellinus linteus induces G0/G1 cell cycle arrest and apoptosis in NB4 human leukaemia cells.

Hispolon (a phenolic compound isolated from Phellinus linteus) has been shown to possess strong antioxidant, anti-inflammatory, anticancer, and antidiabetic properties..

OncologyImmune supportMetabolic healthLiver support

Medium relevance

Chaga · 2013 · Research Support, Non U.S. Gov'T · Molecular medicine reports

Inhibitory effects of low molecular weight polyphenolics from Inonotus obliquus on human DNA topoisomerase activity and cancer cell proliferation.

Low molecular weight (LMW) polyphenolics containing a polyhydroxylated benzyl moiety are abundant in medicinal plants. In the present study, we report on the activities of seven LMW polyphenolics isolated from Inonotus obliquus, a medicinal mushroom..

OncologyMetabolic healthGut & microbiome

Medium relevance

Maitake · 2013 · Research Support, Non U.S. Gov'T · Biotechnology and applied biochemistry

Inhibitory potential of Grifola frondosa bioactive fractions on α-amylase and α-glucosidase for management of hyperglycemia.

This study examined the inhibitory effects of Grifola frondosa (GF), a medicinal mushroom popularly consumed in traditional medicine and health food, on digestive enzymes related to type 2 diabetes; chemical profiles and inhibitory kinetics of its bioactive fractions were also analyzed..

Metabolic healthGut & microbiome

Medium relevance

Turkey Tail · 2013 · Research Support, Non U.S. Gov'T · Environmental technology

Laccase production by Trametes versicolor under limited-growth conditions using dyes as inducers.

Laccase production by pre-growth pellets of Trametes versicolor using two types of textile dyes as inducers was studied. By decoupling the enzyme production phase from the growth phase, it is possible to reduce the time and nutrients required for laccase production..

Metabolic health

Medium relevance

Lion's Mane · 2012 · English Abstract · Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]

[Submerged cultivation and chemical composition of Hericium erinaceus mycelium].

Submerged cultivation of Hericium erinaceus in various media was studied. The yield of the biomass was shown to depend mainly on the carbon source, whereas the content of water soluble polysaccharides depended mainly on the nitrogen source..

Immune supportMetabolic health

Medium relevance

Niu-Chang-Chih · 2012 · Research Support, Non U.S. Gov'T · Phytomedicine: international journal of phytotherapy and phytopharmacology

Antileukemia component, dehydroeburicoic acid from Antrodia camphorata induces DNA damage and apoptosis in vitro and in vivo models.

Antrodia camphorata (AC) is a native Taiwanese mushroom which is used in Asian folk medicine as a chemopreventive agent. The triterpenoid-rich fraction (FEA) was obtained from the ethanolic extract of AC and characterized by high performance liquid chromatography (HPLC)..

OncologyEnergy & fatigueMetabolic health

Medium relevance

Chaga · 2012 · Evaluation Study · Carbohydrate polymers

Antitumor and immunomodulatory activity of water-soluble polysaccharide from Inonotus obliquus.

The medicinal mushroom Inonotus obliquus has been used as a folk remedy for a long time in Russia and East-European countries to treat gastrointestinal cancer, cardiovascular disease and diabetes. In our study, a water-soluble polysaccharide (ISP2a) was successfully purified from I..

OncologyImmune supportMetabolic healthGut & microbiome

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · World journal of microbiology & biotechnology

Batch production of Pyranose 2-oxidase from Trametes versicolor (ATCC 11235) in medium with a lignocellulosic substrate and enzymatic bleaching of cotton fabrics.

The aim of this work was to determine new, different and low-cost substrates that can be used for enzyme production from the white rot fungus Trametes versicolor (ATCC 11235) by taking advantage of the broad substrate specificity of pyranose 2-oxidase..

Metabolic health

Medium relevance

Turkey Tail · 2012 · Evaluation Study · Journal of environmental science & engineering

Biological decolourisation of pulp mill effluent using white rot fungus Trametes versicolor.

The conventional biological treatment methods employed in the pulp and paper industries are not effective in reducing the colour and chemical oxygen demand (COD). The white-rot fungi are reported to have the ability to biodegrade the lignin and its derivatives..

Energy & fatigueMetabolic health

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Journal of bioscience and bioengineering

Determination of co-metabolism for 1,1,1-trichloro-2,2-bis(4-chlorophenyl) ethane (DDT) degradation with enzymes from Trametes versicolor U97.

Trametes versicolor U97 isolated from nature degraded 73% of the 1,1,1-trichloro-2,2-bis(4-chlorophenyl) ethane (DDT) in a malt extract liquid medium after a 40-d incubation period. This paper presents a kinetic study of microbial growth using the Monod equation.

Metabolic health

Medium relevance

Enoki · 2012 · Research Support, Non U.S. Gov'T · Animal science journal = Nihon chikusan Gakkaiho

Effects of fermented mushroom (Flammulina velutipes) by-product diets on growth performance and carcass traits in growing-fattening Berkshire pigs.

This study was conducted to investigate effects of fermented mushroom (Flammulina velutipes) by-product diets on the growth performance and carcass traits in growing-fattening Berkshire pigs..

Energy & fatigueMetabolic healthGut & microbiome

Medium relevance

Enoki · 2012 · Research Support, Non U.S. Gov'T · International journal of nanomedicine

Enhanced oral bioavailability of a sterol-loaded microemulsion formulation of Flammulina velutipes, a potential antitumor drug.

PURPOSE: To investigate the growth inhibition activity of Flammulina velutipes sterol (FVS) against certain human cancer cell lines (gastric SGC and colon LoVo) and to evaluate the optimum microemulsion prescription, as well as the pharmacokinetics of encapsulated FVS..

OncologyMetabolic healthGut & microbiome

Medium relevance

Mesima · 2012 · Research Support, Non U.S. Gov'T · Chemico-biological interactions

Hispidin produced from Phellinus linteus protects against peroxynitrite-mediated DNA damage and hydroxyl radical generation.

Oxidative stress plays an important role in the progression of many chronic diseases including cardiovascular diseases, diabetes, cancer and neurodegenerative disorders..

OncologyCognition & nervesMetabolic health

Medium relevance

Niu-Chang-Chih · 2012 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

In vivo antitumor effects of 4,7-dimethoxy-5-methyl-1,3-benzodioxole isolated from the fruiting body of Antrodia camphorata through activation of the p53-mediated p27/Kip1 signaling pathway.

In this study, 4,7-dimethoxy-5-methyl-1,3-benzodioxole (SY-1) was isolated from three different sources of dried Antrodia camphorata (AC) fruiting bodies. AC is a medicinal mushroom that grows on the inner heartwood wall of Cinnamomum kanehirai Hay (Lauraceae), which is an endemic species that is used in Chinese….

OncologyImmune supportMetabolic healthGut & microbiome

Medium relevance

Snow Fungus · 2012 · Research Support, Non U.S. Gov'T · Journal of radiation research

Protective Effect of Polysaccharides Isolated from Tremella fuciformis against Radiation-induced Damage in Mice

WTF-B, a type of water-soluble homogeneous polysaccharide, was isolated and purified from Tremella Fuciformis. To investigate the radioprotective effect of WTF-B, we employed a 30-day survival assay.

Immune supportMetabolic healthGut & microbiome

Medium relevance

Zhu Ling · 2012 · Research Support, Non U.S. Gov'T · Glycobiology

Structure elucidation and immunological function analysis of a novel β-glucan from the fruit bodies of Polyporus umbellatus (Pers.) Fries.

β-Glucans derived from various sources such as yeast cell walls and medicinal mushrooms are considered as valuable biological response modifiers for their ability to enhance the activity of immune cells, aid in wound healing and help prevent infections..

Immune supportMetabolic healthSkin & hydration

Medium relevance

Snow Fungus · 2012 · Research Support, Non U.S. Gov'T · Behavioural brain research

Tremella fuciformis enhances the neurite outgrowth of PC12 cells and restores trimethyltin-induced impairment of memory in rats via activation of CREB transcription and cholinergic systems.

The present study examined the effects of Tremella fuciformis (TF) on the learning and memory function and the neural activity in rats with trimethyltin (TMT)-induced memory deficits. The rats were administered saline or TF (TF 25, 50, 100 mg/kg, p.o.) daily for 21 days..

Immune supportCognition & nervesMetabolic health

Medium relevance

Turkey Tail · 2011 · Research Support, Non U.S. Gov'T · Bioresource technology

Biological pretreatment with a cellobiose dehydrogenase-deficient strain of Trametes versicolor enhances the biofuel potential of canola straw.

The use of Trametes versicolor as a biological pretreatment for canola straw was explored in the context of biofuel production. Specifically, the effects on the straw of a wild-type strain (52J) and a cellobiose dehydrogenase (CDH)-deficient strain (m4D) were investigated..

Metabolic health

Medium relevance

Chaga · 2011 · Comparative Study · Biological trace element research

Comparison of hypoglycemic activity of fermented mushroom of Inonotus obliquus rich in vanadium and wild-growing I. obliquus.

The effects of vanadium-enriched and wild Inonotus obliquus were tested on hyperglycemic mice. The vanadium content of the culture medium was 0.6%, reaching a concentration of 3.0 mg/g in the cultured mushroom while in the wild variety is 1/100 of that amount..

Metabolic health

Medium relevance

Enoki · 2011 · Research Support, Non U.S. Gov'T · Current microbiology

Identification of differentially expressed genes in Flammulina velutipes with anti-tyrosinase activity.

It was previously shown that fruiting bodies of the mushroom, Flammulina velutipes, exert anti-tyrosinase activity by producing a triacylglycerol characterized as 1',3'-dilinolenoyl-2'-linoleoylglycerol (LnLLn). In this study, we provide evidence that the mycelia of F..

Metabolic health

Medium relevance

Chaga · 2011 · Research Support, Non U.S. Gov'T · Applied microbiology and biotechnology

Involvements of S-nitrosylation and denitrosylation in the production of polyphenols by Inonotus obliquus.

Nitric oxide (NO) has been evidenced to mediate biosynthesis of polyphenols in Inonotus obliquus. However, it remains unknown how NO regulates their biosynthesis..

Metabolic health

Medium relevance

Niu-Chang-Chih · 2011 · Evaluation Study · Applied microbiology and biotechnology

Optimization of fermentation medium for triterpenoid production from Antrodia camphorata ATCC 200183 using artificial intelligence-based techniques.

In this study, alteration in morphology of submergedly cultured Antrodia camphorata ATCC 200183 including arthroconidia, mycelia, external and internal structures of pellets was investigated..

Metabolic health

Medium relevance

Maitake · 2011 · Comparative Study · Journal of agricultural and food chemistry

Profiling of hepatic gene expression of mice fed with edible japanese mushrooms by DNA microarray analysis: comparison among Pleurotus ostreatus, Grifola frondosa, and Hypsizigus marmoreus.

To compare and estimate the effects of dietary intake of three kinds of mushrooms (Pleurotus ostreatus, Grifola frondosa, and Hypsizigus marmoreus), mice were fed a diet containing 10-14% of each mushroom for 4 weeks. Triacylglycerol in the liver and plasma decreased and plasma cholesterol increased in the P..

Immune supportMetabolic healthLiver supportRespiratory

Medium relevance

Maitake · 2011 · Patent · journal metadata

SUBSTANCE DERIVED FROM GRIFOLA FRONDOSA FOR INHIBITING INCREASE OF POSTPRANDIAL HYPERGLYCEMIA

Provided are a pharmaceutical product, food or drink, or other product wherein it is possible to safely treat or improve postprandial hyperglycemia without causing any side effects..

Metabolic health