MycoData

Maitake · 1985 · Journal Article · Chemical and Pharmaceutical Bulletin

Purification and Structural Characterization of an Antitumor β-1, 3-Glucan Isolated from Hot Water Extract of the Fruit Body of Cultured Grifola frondosa

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Chemical and Pharmaceutical Bulletin in 1985. MycoData maps the paper to oncology based on its title, species context, article metadata, and study classification..

Maitake · 1985 · Journal Article · Chemical & pharmaceutical bulletin

Structural characterization and antitumor activity of the extracts from matted mycelium of cultured Grifola frondosa.

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Chemical & pharmaceutical bulletin in 1985. MycoData maps the paper to oncology based on its title, species context, article metadata, and study classification..

Maitake · 1985 · Journal Article · Chemical & pharmaceutical bulletin

Structure-Function Relationship of Antitumor β-1, 3-Glucan Obtained from Matted Mycelium of Cultured Grifola frondosa

Reishi · 1985 · Journal Article · Agricultural and Biological Chemistry

Structures and Antitumor Activities of the Polysaccharides Isolated from Fruiting Body and the Growing Culture of Mycelium of Ganoderma lucidum

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Agricultural and Biological Chemistry in 1985. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..

OncologyImmune supportMetabolic healthLiver support

Reishi · 1985 · Journal Article · Chemical and Pharmaceutical Bulletin

Structures of New Terpenoid Constituents of Ganoderma lucidum (Fr.) KARST (Polyporaceae)

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Chemical and Pharmaceutical Bulletin in 1985. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

OncologyImmune supportMetabolic healthLiver support

Reishi · 1985 · Journal Article · Chemical and Pharmaceutical Bulletin

The Biologically Active Constituents of Ganoderma lucidum (FR.) KARST. Histamine Release-Inhibitory Triterpenes

Maitake · 1984 · Journal Article · Chemical & pharmaceutical bulletin

Antitumor activity and structural characterization of glucans extracted from cultured fruit bodies of Grifola frondosa.

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Chemical & pharmaceutical bulletin in 1984. MycoData maps the paper to oncology based on its title, species context, article metadata, and study classification..

OncologyImmune supportMetabolic healthLiver support

Reishi · 1984 · Journal Article · Agricultural and Biological Chemistry

Streptomyces Pepsin Inhibitor-insensitive Carboxyl Proteinase from Ganoderma lucidum

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Agricultural and Biological Chemistry in 1984. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

Wood Ear · 1983 · Journal Article · Chemical & pharmaceutical bulletin

Polysaccharides in fungi. XIII. Antitumor activity of various polysaccharides isolated from Dictyophora indusiata, Ganoderma japonicum, Cordyceps cicadae, Auricularia auricula-judae, and Auricularia species.

Metadata-grounded summary: This journal article indexes research on Auricularia auricula-judae in Chemical & pharmaceutical bulletin in 1983. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..

OncologyImmune supportMetabolic healthLiver support

Reishi · 1983 · Journal Article · YAKUGAKU ZASSHI

Studies on Ganoderma lucidum. IV. Effects on the Disseminated Intravascular Coagulation

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in YAKUGAKU ZASSHI in 1983. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

Enoki · 1982 · Journal Article · JOURNAL OF THE JAPANESE ASSOCIATION OF RURAL MEDICINE

Antitumor Activity of a Hot Water Extract of Flammulina velutipes Sing

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in JOURNAL OF THE JAPANESE ASSOCIATION OF RURAL MEDICINE in 1982. MycoData maps the paper to oncology based on its title, species context, article metadata, and study classification..

Maitake · 1982 · Journal Article · Japanese Journal of Medical Mycology

Antitumor Activity of Fruiting Bodies of Cultured Grifola frondosa

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Japanese Journal of Medical Mycology in 1982. MycoData maps the paper to oncology based on its title, species context, article metadata, and study classification..

Reishi · 1981 · Journal Article · Chemical and Pharmaceutical Bulletin

Studies on Fungal Polysaccharides. XXVII. Structural Examination of a Water-soluble, Antitumor Polysaccharide of Ganoderma lucidum

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Chemical and Pharmaceutical Bulletin in 1981. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..

Turkey Tail · 1980 · Journal Article · The Journal of General and Applied Microbiology

THE BREAKDOWN OF COCONUT FIBERS BY TRAMETES VERSICOLOR AND STEREUM RUGOSUM

Metadata-grounded summary: This journal article indexes research on Trametes versicolor in The Journal of General and Applied Microbiology in 1980. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..

OncologyCognition & nerves

Almond Mushroom · 2023 · Preprint · journal metadata

An agent based model (ABM) to reproduce the boolean logic behaviour of neuronal self organized communities through pulse delay modulation and generation of logic gates

The human brain is arguably the most complex “machine” to ever exist. Its detailed functioning is yet to be fully understood, let alone modeled.

Cordyceps · 2022 · Meta-Analysis · Gastroenterology

Altered Mycobiota Signatures and Enriched Pathogenic Aspergillus rambellii Are Associated With Colorectal Cancer Based on Multicohort Fecal Metagenomic Analyses.

BACKGROUND & AIMS: The enteric mycobiota is a major component of the human gut microbiota, but its role in colorectal cancer (CRC) remains largely elusive. We conducted a meta-analysis to uncover the contribution of the fungal mycobiota to CRC..

OncologyGut & microbiome

Nameko · 2020 · Journal Article · International journal of biological macromolecules

A novel antitumor protein from the mushroom Pholiota nameko induces apoptosis of human breast adenocarcinoma MCF-7 cells in vivo and modulates cytokine secretion in mice bearing MCF-7 xenografts.

Breast cancer is the most common malignant tumor in women and one of the three most common cancers worldwide. It is a life-threatening disease among women and the leading cause of death among women.

Oyster Mushroom · 2020 · Journal Article · Journal of oleo science

Effects of Sphingolipid Fractions from Golden Oyster Mushroom (Pleurotus citrinopileatus) on Apoptosis Induced by Inflammatory Stress in an Intestinal Tract in vitro Model

Previously, we reported that the polar lipid fraction from the golden oyster mushroom, Pleurotus citrinopileatus, suppresses colon injuries which result from apoptosis induced by inflammatory stresses in vivo and in vitro (Yamashita et al., J. Oleo Sci., 69, 751-757 (2020))..

Nameko · 2020 · Journal Article · Natural product research

One new sterpurane sesquiterpene from cultures of the basidiomycete Pholiota nameko.

One new sterpurane sesquiterpene (1), named (3R,6S,7S,8R,10S)-3,7,14-trihydroxy-1-sterpurene was isolated from cultures of the basidiomycete Pholiota nameko. The structure of new compound was elucidated by extensive spectroscopic..

Shiitake · 2019 · Journal Article · International journal of biological macromolecules

Preparation and properties of water-in-oil shiitake mushroom polysaccharide nanoemulsion.

Shiitake mushroom (Lentinus edodes) polysaccharide (SMP), an important immunomodulatory substance, is usually hard to be absorbed by the intestinal tract, because of its macromolecule characteristics..

Nameko · 2019 · Journal Article · Natural product research

Two new sesquiterpenes from cultures of the higher fungus Pholiota nameko.

Two new sesquiterpenes (1-2), along with one known sesquiterpene (3), were isolated from cultures of the higher fungus Pholiota nameko. The structures of new compounds were elucidated by extensive spectroscopic methods..

OncologyImmune supportEnergy & fatigueMetabolic health

Shiitake · 2018 · Journal Article · ACS applied materials & interfaces

Conformation-Dependent Manipulation of Human Islet Amyloid Polypeptide Fibrillation by Shiitake-Derived Lentinan.

Misfolding and aggregation of human islet amyloid polypeptide (hIAPP) into fibrils are important contributions to the pathology of type 2 diabetes. Developing effective inhibitors of protein aggregation and fibrillation has been considered a promising therapeutic approach to preventing and treating type 2 diabetes..

OncologyEnergy & fatigueRespiratory

Shiitake · 2018 · Journal Article · International journal of medicinal mushrooms

Extrinsic and Intrinsic Apoptotic Responses Induced by Shiitake Culinary-Medicinal Mushroom Lentinus edodes (Agaricomycetes) Aqueous Extract against a Larynx Carcinoma Cell Line.

Cumulative evidence from research studies has shown that the shiitake culinary-medicinal mushroom, Lentinus edodes, is an excellent source of natural antitumor agents and is capable of inhibiting cancer cell growth..

Shiitake · 2017 · Journal Article · International journal of medicinal mushrooms

Selective Cytotoxic Activity of Se-Methyl-Seleno-L-Cysteine- and Se-Polysaccharide-Containing Extracts from Shiitake Medicinal Mushroom, Lentinus edodes (Agaricomycetes).

Numerous formulations derived from the shiitake medicinal mushroom, Lentinus edodes, demonstrate anticancer activities. We hypothesized that isolates from selenium (Se)-enriched mycelia of L.

Nameko · 2016 · Journal Article · International journal of medicinal mushrooms

A Polysaccharide from the Culinary-Medicinal Mushroom Pholiota nameko (Agaricomycetes) Inhibits the NF-κB Pathway in Dendritic Cells Through the TLR2 Receptor.

A polysaccharide purified from Pholiota nameko (PNPS-1) was found to have anticancer and anti-inflammatory activity. This study investigated the effect of PNPS-1 on the nuclear factor (NF)-κB signaling pathway of TLR2 small interfering RNA-silenced murine bone marrow-derived dendritic cells (BMDCs) and relevant….

OncologyImmune supportGut & microbiomeRespiratory

Shiitake · 2016 · Journal Article · Journal of agricultural and food chemistry

Elm Tree (Ulmus parvifolia) Bark Bioprocessed with Mycelia of Shiitake (Lentinus edodes) Mushrooms in Liquid Culture: Composition and Mechanism of Protection against Allergic Asthma in Mice.

Mushrooms can break down complex plant materials into smaller, more digestible and bioactive compounds. The present study investigated the antiasthma effect of an Ulmus parvifolia bark extract bioprocessed in Lentinus edodes liquid mycelium culture (BPUBE) against allergic asthma in chicken egg ovalbumin….

Chaga · 2009 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Potential anticancer properties of the water extract of Inonotus [corrected] obliquus by induction of apoptosis in melanoma B16-F10 cells.

ETHNOPHARMACOLOGICAL RELEVANCE: Inonotus obliquus (Chaga mushroom), one of the widely known medicinal mushrooms, has been used to treat various cancers in Russia and most of Baltic countries for many centuries..

Lion's Mane · 2007 · Patent · journal metadata

CORN MUSHROOM MIXED TEA

Mushroom tea containing Hericium erinaceus(Lion's Mane) and corn is provided which has the efficacy of Hericium erinaceus such as nausea relieving effect, anticancer effect and the like..

OncologyImmune supportMetabolic health

Maitake · 2002 · Journal Article · Research communications in molecular pathology and pharmacology

Effects of Maitake mushroom fractions on blood pressure of Zucker fatty rats.

A link exists between insulin resistance and many chronic disorders of aging including advancing-age. A safer means to prevent or, at least, slow the erosion of insulin sensitivity would provide a novel approach to better health..

Maitake · 2000 · Journal Article · Molecular urology

Induction of apoptosis in human prostatic cancer cells with beta-glucan (Maitake mushroom polysaccharide).

PURPOSE: To explore more effective treatment for hormone-refractory prostate cancer, we investigated the potential antitumor effect of beta-glucan, a polysaccharide of the Maitake mushroom, on prostatic cancer cells in vitro..

OncologyCognition & nervesEnergy & fatigueRespiratory

Cordyceps · 2026 · Review Article · Neural regeneration research

Modulation of mitochondrial dysfunction: Mechanisms and strategies for the use of natural products to treat stroke.

Modulations of mitochondrial dysfunction, which involve a series of dynamic processes such as mitochondrial biogenesis, mitochondrial fusion and fission, mitochondrial transport, mitochondrial autophagy, mitochondrial apoptosis, and oxidative stress, play an important role in the onset and progression of stroke..

Cordyceps · 2026 · Review · The American journal of Chinese medicine

Research Progress on the Molecular Mechanisms of Cordycepin in Modulating Inflammation.

Cordycepin is a bioactive compound isolated from the Cordyceps fungi. It is structurally analogous to adenosine and possesses potent anti-inflammatory and immunomodulatory properties..

OncologyImmune supportCognition & nervesLiver support

Niu-Chang-Chih · 2025 · Review · Journal of the Chinese Medical Association: JCMA

Anti-inflammatory and anticancer effects of polysaccharides from Antrodia cinnamomea: A review.

Antrodia cinnamomea ( Ac ), also known as "Niu-Chang-Chih" in Chinese, is a valuable fungus that has been widely used as medicine and food among indigenous people in Taiwan. Ac is rich in polysaccharides ( Ac -PS), making it a promising candidate for adjunctive therapy in cancer and inflammation conditions..

Cordyceps · 2025 · Review · Journal of food and drug analysis

Cordycepin in cancer therapy: A bibliometric analysis and review of mechanisms.

Cordycepin (3'-deoxyadenosine), a major bioactive component derived from fungi of the genus Cordyceps, has garnered significant attention in recent years for its potent antitumor properties..

Zhu Ling · 2025 · Preprint · journal metadata

Fluorescence and Phosphorescence Assay of -D Glucans from Basidiomycete Medicinal Mushrooms

Basidiomycete mushrooms contain complex -D-glucans which play an important role in immuno-modulating and anti-tumor activities. The present work involves a novel and intrinsic synchronous fluorescent and phosphorescence assay method for -D-glucans..

Shiitake · 2025 · Review · International journal of molecular sciences

Food-Derived Phytochemicals: Multicultural Approaches to Oxidative Stress and Immune Response.

This review will focus on how ethnic consumption of foods such as shiitake, ginseng, turmeric, black seeds, berries, rosemary, moringa and holy basil can help act as antioxidants and immune modulators in fighting many diseases..

OncologyImmune supportMetabolic health

Reishi · 2025 · Preprint · journal metadata

Genome-Wide CRISPR/Cas9 Screening Reveals Lipid Metabolism and Inflammatory Signalling as Modulators of Ganoderic Acid DM Cytotoxicity

Ganoderic Acid DM (GA-DM), a triterpenoid derived from Ganoderma lucidum, exhibits anti-cancer and anti-diabetic activities, but the underlying mechanisms of action remain unclear. To identify genetic modulators of GA-DM response, we conducted a genome-wide CRISPR/Cas9 knockout screen in human melanoma cells..

Cordyceps · 2025 · Review · Food science & nutrition

Mushroom Bioactive Molecules as Anticancerous Agents: An Overview.

Mushrooms have long been used in Traditional Chinese medicine (TCM), where they play an important role in promoting overall health and well-being. However, the therapeutic benefits of mushrooms have made this group of macrofungi a significant part of traditional medicine, particularly in Southeast Asia and China..

OncologyImmune supportCognition & nervesMetabolic health

Chaga · 2025 · Preprint · journal metadata

Mushroom-Derived Compounds as Inhibitors of Advanced Glycation End-Products

Mushrooms have long been valued not only as food but also for their medicinal properties, especially in Eastern European traditional medicine. Species such as Inonotus obliquus, Fomitopsis officinalis, Piptoporus betulinus and Fomes fomentarius have been used to treat gastrointestinal problems, cancers, respiratory….

OncologyImmune supportLiver support

Reishi · 2025 · Preprint · journal metadata

Potential for Medicinal Mushroom Extracts as an Adjunctive Treatment to Enhance Conversion Therapy in Colorectal Cancer with Liver and Peritoneal Involvement

Colorectal cancer (CRC) with liver metastases (LM) and peritoneal metastases (PM) presents a formidable challenge, with poor prognosis despite advances in systemic chemotherapy and combined surgical approaches like cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)..

OncologyImmune supportLiver support

Reishi · 2025 · Preprint · journal metadata

Potential for Medicinal Mushroom Extracts as an Adjunctive Treatment to Enhance Conversion Therapy in Colorectal Cancer with Liver and Peritoneal Involvement

Oyster Mushroom · 2025 · Review · Foods (Basel, Switzerland)

The Emerging Role of Oyster Mushrooms as a Functional Food for Complementary Cancer Therapy.

The importance of functional food's role in human nutrition as well as in the prevention of diseases, especially the treatment of chronic diseases like cancer, is an innovative field of research..

Almond Mushroom · 2024 · Review · Artificial intelligence in medicine

Agent-based approaches for biological modeling in oncology: A literature review.

CONTEXT: Computational modeling involves the use of computer simulations and models to study and understand real-world phenomena. Its application is particularly relevant in the study of potential interactions between biological elements..

OncologyEnergy & fatigue

Cordyceps · 2024 · Review · Molecular medicine reports

Application and research progress of cordycepin in the treatment of tumours (Review).

Cordycepin is a nucleoside molecule found in Cordyceps sinensis and can be obtained through chemical synthesis and biotransformation. Cordycepin has been extensively studied and has been shown to have antitumour activity..

OncologyImmune supportEnergy & fatigueGut & microbiome

Oyster Mushroom · 2024 · Preprint · journal metadata

Computational Development of mushroom-6-Glucan/Paclitaxel as a Synergistic Complementary Medicine for Breast Cancer Therapy

Abstract Background Breast cancer is chemo-resistant and highly metastatic, often resulting in patient mortality. One of the primary factors contributing to the metastasis and chemotherapy resistance is the presence of cancer stem-like cells..

OncologyCognition & nerves

Almond Mushroom · 2024 · Abstract · Neuro-oncology

CTNI-11. A PHASE 1 OPEN-LABEL STUDY OF BRAF INHIBITOR ABM-1310 IN PATIENTS (PTS) WITH RECURRENT BRAF V600-MUTATED PRIMARY CNS TUMORS

Metadata-grounded summary: This abstract indexes research on Agaricus blazei in Neuro-oncology in 2024. MycoData maps the paper to oncology, cognition & nerves based on its title, species context, article metadata, and study classification..

OncologyImmune supportRespiratory

Cordyceps · 2024 · Review · Current topics in medicinal chemistry

Pharmacological Effects of FTY720 and its Derivatives.

FTY720 is an analog of sphingosine-1-phosphate (S1P) derived from the ascomycete Cordyceps sinensis. As a new immunosuppressant, FTY720 is widely used to treat multiple sclerosis.

OncologyImmune supportCognition & nervesGut & microbiome

Lion's Mane · 2024 · Review · Journal of ethnopharmacology

The ethnopharmacology, phytochemistry and pharmacology of the genus Hericium.

ETHNOPHARMACOLOGICAL RELEVANCE: Mushrooms in the genus Hericium are used as functional food and traditional medicines for a long history in East Asian countries such as China, India, Japan, and Korea..