MycoData

Expensive fetal bovine serum (FBS) is a major obstacle to the production of cultivated meat. However, because FBS substitutes do not sufficiently induce cell proliferation, a good alternative is to reduce the amount of FBS and use ingestible additives to promote cell proliferation..

Energy & fatigue

High relevance

Maitake · 2024 · Journal Article · Molecular nutrition & food research

Grifola frondosa Polysaccharide Ameliorates Inflammation by Regulating Macrophage Polarization of Liver in Type 2 Diabetes Mellitus Rats.

SCOPE: Grifola frondosa polysaccharide (GFP) has a positive effect in regulating type 2 diabetes mellitus (T2DM), but the understanding of its regulatory mechanism is still limited. Accumulating evidence suggests that hepatic inflammation is crucial in the onset and progression of insulin resistance (IR) and T2DM..

Immune supportMetabolic healthLiver support

High relevance

Oyster Mushroom · 2024 · Research Article · Mycobiology

Growth and Yield Performance of Pleurotus ostreatus Cultivated on Agricultural Residues.

Food insecurity and malnutrition are among the major problems in most developing nations recently. Mushroom cultivation is one of the promising strategies to overcome these challenges.

Energy & fatigueGut & microbiome

High relevance

Yellow Morel · 2024 · Journal Article · International journal of biological macromolecules

Gut microbiota combined with serum metabolites to reveal the effect of Morchella esculenta polysaccharides on lipid metabolism disordered in high-fat diet mice.

The ameliorating effects and mechanisms of Morchella esculenta polysaccharides (MEP-1) on lipid metabolism were investigated in high-fat diet (HFD) mice. The results showed that MEP-1 intervention significantly reduced serum TC, TG, LDL-C, and inflammatory factors (TNF-α, IL-1β and IL-6) in HFD mice in a….

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Shiitake · 2024 · Research Article · Nutrients

Hepatoprotection of a Standardized Extract of Cultured Lentinula edodes Mycelia against Liver Injury Induced by Ischemia-Reperfusion and Partial Hepatectomy.

A standardized extract of cultured Lentinula edodes mycelia (ECLM, AHCC®) has been shown to have beneficial effects on organ metabolism. ECLM has been indicated to have liver protective properties by suppressing inflammatory responses..

OncologyImmune supportLiver support

High relevance

Niu-Chang-Chih · 2024 · Research Article · Nutrients

Hepatoprotective Effect of Antrodia camphorata Mycelium Powder on Alcohol-Induced Liver Damage.

BACKGROUND/OBJECTIVES: Antrodia camphorata, also known as "Niuchangchih" in Taiwan, is a unique medicinal mushroom native to Taiwan. It is used in traditional medicine to treat various health conditions.

Immune supportMetabolic healthLiver support

High relevance

Lion's Mane · 2024 · Journal Article · Chemistry & biodiversity

Hericium erinaceus Extract Induces Apoptosis via PI3K/AKT and RAS/MAPK Signaling Pathways in Prostate Cancer Cells.

Prostate cancer (PCa) is increasing globally, surpassing lung cancer in incidence. Despite available treatment options, prostate cancer remains incurable.

OncologyRespiratory

High relevance

Lion's Mane · 2024 · Journal Article · International journal of biological macromolecules

Hericium erinaceus polysaccharides ameliorate nonalcoholic fatty liver disease via gut microbiota and tryptophan metabolism regulation in an aged laying hen model.

Polysaccharides extracted from Hericium erinaceus (HEP) exhibit hepatoprotective activity in the alleviation of non-alcoholic fatty liver disease (NAFLD); however, the mechanisms underlying whether and how HEP regulation of the gut microbiota to alleviate liver-associated metabolic disorders are not well understood..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Lion's Mane · 2024 · Journal Article · International journal of biological macromolecules

Hericium erinaceus β-glucan/tannic acid hydrogels based on physical cross-linking and hydrogen bonding strategies for accelerating wound healing.

The majority of natural fungal β-glucans exhibit diverse biological functionalities, such as immunomodulation and anti-inflammatory effects, attributed to their distinctive helix or highly branched conformation This study utilized β-glucan with helix conformation and high-viscosity extracted from Hericium erinaceus,….

Immune supportSkin & hydration

High relevance

Lion's Mane · 2024 · Journal Article · Journal of Asian natural products research

Hericium VN, an undescribed compound isolated from Hericium erinaceus and its cytotoxic activity on human brain astrocytoma.

Hericium erinaceus is a species of mushroom with high nutritional value that is used mainly as food in tropical countries. Phytochemical study of H.

OncologyCognition & nerves

High relevance

Reishi · 2024 · Journal Article · World J Microbiol Biotechnol

Heterologous expression and characterization of a dye-decolorizing peroxidase from Ganoderma lucidum, and its application in decolorization and detoxifization of different types of dyes

Dye-decolorizing peroxidases (DyPs) belong to a novel superfamily of heme peroxidases that can oxidize recalcitrant compounds. In the current study, the GlDyP2 gene from Ganoderma lucidum was heterologously expressed in Escherichia coli, and the enzymatic properties of the recombinant GlDyP2 protein were investigated..

High relevance

Reishi · 2024 · Journal Article · World journal of microbiology & biotechnology

Heterologous expression and characterization of a dye-decolorizing peroxidase from Ganoderma lucidum, and its application in decolorization and detoxifization of different types of dyes.

High relevance

Enoki · 2024 · Journal Article · Journal of agricultural and food chemistry

Homeodomain 1 Genes of the Different HD Subloci of Flammulina velutipes Can Activate the HD Pathway and Are Involved in Mating, Clamp Cell Formation, and Upregulation of FvClp1.

Flammulina velutipes has two independent and functional mating type factors, HD and PR. The HD locus contains two separate subloci: HD-a and HD-b.

High relevance

Shiitake · 2024 · Research Article · Journal of fungi (Basel, Switzerland)

Homologous Delta-12 Fatty Acid Desaturase (FAD2) Genes Affect Gene Expression and Linoleic Acid Levels in Lentinula edodes under Heat Stress.

Delta-12 fatty acid desaturases (FAD2s) actively regulate stress responses and cell differentiation in living organisms. In this study, six homologous FAD2 genes were identified based on the genome sequence of Lentinula edodes..

High relevance

Chaga · 2024 · Journal Article · Food chemistry

How lignocellulose degradation can promote the quality and function of dietary fiber from bamboo shoot residue by Inonotus obliquus fermentation.

Lignocellulose constitutes the primary component of dietary fiber. We assessed how fermenting bamboo shoot residue with the medicinal white-rot fungus Inonotus obliquus affected the yield, composition, and functional attributes of dietary fiber by altering bamboo shoot residue lignocellulose's spatial structure and….

Metabolic healthSkin & hydration

High relevance

Oyster Mushroom · 2024 · Research Article · Plants (Basel, Switzerland)

Hydroalcoholic Extracts from Pleurotus ostreatus Spent Substrate with Nematocidal Activity against Nacobbus aberrans Phytonematode and the Non-Target Species Panagrellus redivivus.

Pleurotus ostreatus, an edible mushroom widely consumed worldwide, generates a by-product known as spent mushroom substrate (SMS). This material has demonstrated biological activity against agricultural crop pathogens..

High relevance

Reishi · 2024 · Research Article · Redox biology

Hydrogen sulfide maintains mitochondrial homeostasis and regulates ganoderic acids biosynthesis by SQR under heat stress in Ganoderma lucidum.

Hydrogen sulfide (H2S) has recently been recognized as an important gaseous transmitter with multiple physiological effects in various species. Previous studies have shown that H2S alleviated heat-induced ganoderic acids (GAs) biosynthesis, an important quality index of Ganoderma lucidum..

Energy & fatigue

High relevance

Zhu Ling · 2024 · Research Article · Journal of fungi (Basel, Switzerland)

Identification of Growth-Promoting Bacterial Resources by Investigating the Microbial Community Composition of Polyporus umbellatus Sclerotia.

The sclerotium of the edible mushroom Polyporus umbellatus (Zhuling) exhibits various medicinal properties. However, given its long growth cycle and overexploitation, wild resources are facing depletion.

Immune support

High relevance

Turkey Tail · 2024 · Research Article · Scientific reports

Identification of redox activators for continuous reactivation of glyoxal oxidase from Trametes versicolor in a two-enzyme reaction cascade.

Glyoxal oxidases, belonging to the group of copper radical oxidases (CROs), oxidize aldehydes to carboxylic acids, while reducing O2 to H2O2. Their activity on furan derivatives like 5-hydroxymethylfurfural (HMF) makes these enzymes promising biocatalysts for the environmentally friendly synthesis of the bioplastics….

High relevance

Turkey Tail · 2024 · Journal Article · Mycotoxin research

Immobilization of recombinant Trametes versicolor aflatoxin B1-degrading enzyme (TV-AFB1D) with montmorillonite for absorption and in situ degradation of aflatoxin B1.

Aflatoxin B1 is a highly carcinogenic and teratogenic substance mainly produced by toxin-producing strains such as Aspergillus flavus and Aspergillus parasitic. The efficient decomposition of aflatoxin is an important means to reduce its harm to humans and livestock..

High relevance

Oyster Mushroom · 2024 · Research Article · Scientific reports

Impact of bottom ash addition on Pleurotus ostreatus cultivation on coffee ground substrate.

The study aimed to explore the potential use of coal-fired power plant bottom ashes in Pleurotus ostreatus cultivation using spent coffee grounds. The study analyzed five compositions of growth substrate for mushrooms: pure coffee grounds (I) as a control sample; coffee grounds substrate with the addition of 1% (II);….

High relevance

Enoki · 2024 · Journal Article · Food chemistry

Impact of Flammulina velutipes polysaccharide on properties and structural changes of pork myofibrillar protein during the gel process in the absence or presence of oxidation.

The present study aimed to investigate the impact of Flammulina velutipes polysaccharide (FVSP) on the rheological properties and structural alterations of myofibrillar protein (MP) and oxidized MP (OMP), utilizing techniques such as rhehometer, fourier transform infrared spectroscopy (FTIR), scanning electron….

Immune support

High relevance

Reishi · 2024 · Research Article · Food chemistry: X

Impact of Ganoderma lucidum fermentation on the nutritional composition, structural characterization, metabolites, and antioxidant activity of Soybean, sweet potato and Zanthoxylum pericarpium residues.

One of the major issues in the food sector is the lack of resource utilization and the contamination of the environment caused by by-products. This study aimed to investigate the effects of Ganoderma lucidum (GL) fermentation on the nutritional components, structural characterization, metabolites, and antioxidant….

High relevance

Reishi · 2024 · Research Article · Molecules (Basel, Switzerland)

Improvement of Echinacea purpurea and Ganoderma lucidum Extracts with Cell Model on Influenza A/B Infection.

Since 2019, COVID-19 has been raging around the world. Respiratory viral infectious diseases such as influenza and respiratory syncytial virus (RSV) infection are also prevalent, with influenza having the ability to cause seasonal pandemics..

OncologyImmune supportEnergy & fatigueRespiratory

High relevance

Snow Fungus · 2024 · Journal Article · Food chemistry

Improvement of soluble dietary fiber quality in Tremella fuciformis stem by steam explosion technology: An evaluation of structure and function.

Edible fungi by-products are rich in dietary fiber (DF). In this study, we used steam explosion (SE) to modify Tremella fuciformis (T.

Metabolic healthSkin & hydration

High relevance

Oyster Mushroom · 2024 · Research Article · RSC advances

In silico evaluation of potential breast cancer receptor antagonists from GC-MS and HPLC identified compounds in Pleurotus ostreatus extracts.

Introduction: Pharmacotherapeutic targets for breast cancer include the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor (EGFR). Inhibitors of these receptors could be interesting therapeutic candidates for the treatment and management of breast cancer (BC)..

OncologySkin & hydration

High relevance

Oyster Mushroom · 2024 · Journal Article · The Science of the total environment

In situ mycoremediation of acid rain and heavy metals co-contaminated soil through microbial inoculation with Pleurotus ostreatus.

The combined pollution of acid rain and heavy metals in soil is a pressing environmental problem, especially in the regions with large-scale heavy industrial production activities..

Energy & fatigue

High relevance

Snow Fungus · 2024 · Journal Article · Food Research International

In vitro digestion and fecal fermentation of Tremella fuciformis exopolysaccharides from basidiospore-derived submerged fermentation

Tremella fuciformis polysaccharides (TFPS) belong to natural bioactive macromolecule with both edible and medicinal value, possessing much bioactivities such as anti-tumor, antioxidant, antidiabetics, and immunomodulatory..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Snow Fungus · 2024 · Journal Article · Food research international (Ottawa, Ont.)

In vitro digestion and fecal fermentation of Tremella fuciformis exopolysaccharides from basidiospore-derived submerged fermentation.

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Shiitake · 2024 · Journal Article · Brazilian journal of biology = Revista brasleira de biologia

In vitro evaluation of methanol extracts of edible fungi Pleurotus ostreatus and Lentinula edodes against Rhyssomatus nigerrimus Fahraeus.

The study aimed to evaluate the insecticidal activity of extracts of edible mushrooms Pleurotus ostreatus and Lentinula edodes against Rhyssomatus nigerrimus. Methanol:water extracts (70:30) of P.

High relevance

Turkey Tail · 2024 · Research Article · Scientific reports

In-vivo and in-vitro wound healing and tissue repair effect of Trametes versicolor polysaccharide extract.

Regarding different medical benefits of fungi, using the medical mushroom extracts as wound-healing agents is gaining popularity. This study, evaluated the wound healing characteristics of Trametes versicolor..

Immune supportSkin & hydration

High relevance

Reishi · 2024 · Research Article · Frontiers in nutrition

Influence of cultivation substrate on antioxidant activities and triterpenoid profiles of the fruiting body of Ganoderma lucidum.

INTRODUCTION: The fruiting body of Ganoderma lucidum has been believed to possess a wide range of therapeutic effects. There are two main methods for artificial cultivation of G.

High relevance

Cordyceps · 2024 · Journal Article · South African journal of botany

Insights into cultivation strategies, bioactive components, therapeutic potential, patents, and market products of Ophiocordyceps sinensis: A comprehensive review

Ophiocordyceps sinensis (Berk.), a Himalayan bioresource, has garnered considerable scientific and industrial interest due to the presence of numerous bioactive metabolites and extensive biological activities. However, O..

Liver support

High relevance

Enoki · 2024 · Journal Article · International journal of medicinal mushrooms

Insights on Strain-Substrate Interactions and Antioxidant and Anti-Bacterial Properties of the Velvet Foot Medicinal Mushroom Flammulina velutipes (Agaricomycetes).

To study the best substrate for the Indian subcontinent, four different substrates (sawdust + wheat bran, wheat straw + wheat bran + corn cobs, sawdust + corn cobs and wheat straw + wheat bran) were screened for six different Flammulina velutipes strains..

High relevance

Reishi · 2024 · Research Article · Journal of pharmaceutical analysis

Integrating transcriptomics, metabolomics, and network pharmacology to investigate multi-target effects of sporoderm-broken spores of Ganoderma lucidum on improving HFD-induced diabetic nephropathy rats.

Diabetes mellitus (DM) is a major metabolic disease endangering global health, with diabetic nephropathy (DN) as a primary complication lacking curative therapy. Sporoderm-broken spores of Ganoderma lucidum (GLP), an herbal medicine, has been used for the treatment of metabolic disorders..

Immune supportEnergy & fatigueMetabolic health

High relevance

Snow Fungus · 2024 · Journal Article · Talanta

Integration of electronic nose, electronic tongue, and colorimeter in combination with chemometrics for monitoring the fermentation process of Tremella fuciformis.

This study proposes an efficient method for monitoring the submerged fermentation process of Tremella fuciformis (T. fuciformis) by integrating electronic nose (e-nose), electronic tongue (e-tongue), and colorimeter sensors using a data fusion strategy..

Immune supportCognition & nervesEnergy & fatigue

High relevance

Snow Fungus · 2024 · Journal Article · Food Hydrocolloids

Interaction and complex formation of sonicated soluble lentil protein and Tremella fuciformis polysaccharide

Proteins’ physicochemical and structural properties critically affect their interactions with polysaccharides. The effect of ultrasound treatment (0–40 min) on the physicochemical properties of soluble lentil proteins (LPs) was investigated..

Immune support

High relevance

Snow Fungus · 2024 · Research Article · Foods (Basel, Switzerland)

Investigating the Respiratory and Energy Metabolism Mechanisms behind ε-Poly-L-lysine Chitosan Coating's Improved Preservation Effectiveness on Tremella fuciformis.

Freshly harvested Tremella fuciformis contains high water content with an unprotected outer surface and exhibits high respiration rates, which renders it prone to moisture and nutrient loss, leading to decay during storage..

Energy & fatigueMetabolic healthRespiratory

High relevance

Oyster Mushroom · 2024 · Journal Article · Bioresource technology

Investigation of pre-treatment techniques on spent substrate of Pleurotus ostreatus for enhanced biobutanol production using Clostridium acetobutylicum MTCC 11274.

Addressing global energy demand, researchers sought eco-friendly biobutanol production from lignocellulosic waste biomass. In the present research work, five different pre-treatment methods viz., Microwave, Ultrasound, Alkali, Acid, and Hybrid, were investigated to explore its biobutanol production potential by….

Energy & fatigue

High relevance

Lion's Mane · 2024 · Research Article · Foods (Basel, Switzerland)

Isolation and Evaluation of Erinacine A Contents in Mycelia of Hericium erinaceus Strains.

Hericium erinaceus has long been favored for its remarkable nutritional and health-promoting benefits, and erinacine A is the key component responsible for the neuroprotective properties of H. erinaceus.

Cognition & nerves

High relevance

Maitake · 2024 · Journal Article · Journal of the science of food and agriculture

Isolation and identification of active components from Grifola frondosa and its anti-EV71 virus effect.

BACKGROUND: It is reported that anti-enterovirus 71 (EV71) drugs have some side effects on human health. Notably, fungi plays a crucial role in promoting human health and anti-virus.

OncologyEnergy & fatigueRespiratory

High relevance

Maitake · 2024 · Journal Article · Journal of the science of food and agriculture

Isolation and identification of active components from Grifola frondosa and its anti‐EV71 virus effect

BACKGROUND: It is reported that anti‐enterovirus 71 (EV71) drugs have some side effects on human health. Notably, fungi plays a crucial role in promoting human health and anti‐virus.

OncologyEnergy & fatigueRespiratory

High relevance

Maitake · 2024 · Journal Article · Bioscience, biotechnology, and biochemistry

Isolation of bacteria from Grifola frondosa cultivation on wood logs to find mycelial growth-promoting bacteria.

This study aimed to isolate bacteria that coexist with the edible mushroom Grifola frondosa when it is cultured on wood, and to determine their interactions; in turn, the aim was to find bacteria that stimulate mycelial growth so as to decrease the time required for spawn preparation on potato dextrose agar (PDA)..

High relevance

Turkey Tail · 2024 · Journal Article · Chemistry & biodiversity

Isolation, Identification, Phytochemical Characterization, and In Vitro Anti-Inflammatory Property of an Endophytic Trametes Versicolor CL-1 Isolated from Rosa Roxburghii.

This study explores the anti-inflammatory potential of an endophytic fungus, Trametes versicolor CL-1, isolated from the fruit tissues of Rosa roxburghii. Morphological and molecular analyses confirmed the identity of CL-1..

Immune support

High relevance

Snow Fungus · 2024 · Research Article · Molecules (Basel, Switzerland)

iTRAQ-Based Proteomic Profiling of Skin Aging Protective Effects of Tremella fuciformis-Derived Polysaccharides on D-Galactose-Induced Aging Mice.

In the present study, a heteromannan primarily composed of mannose, fucose, xylose, glucose, and arabinose at a molar ratio of 4.78:1.18:1:0.82:0.11 containing a low proportion of glucuronic acid with weight-average molecular weights of 3.6 × 106 Da, named NTP, was prepared from the fruiting body of Tremella….

Immune supportMetabolic healthSkin & hydration

High relevance

Enoki · 2024 · Journal Article · Journal of agricultural and food chemistry

Lipidomic Profiling of Flammulina velutipes (Curtis) Singer (Agaricomycetes) through Ultra-Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry: Examining Lipid Dynamics Changes during Fruiting Body Formation and Development.

Flammulina velutipes (enokitake) is widely recognized for its nutritional and medicinal properties. Understanding the biochemical processes, such as lipid metabolism during fruiting body formation, is essential for enhancing mushroom cultivation and utilization..

Energy & fatigueMetabolic health

High relevance

Cordyceps · 2024 · Research Article · Frontiers in microbiology

Mannitol mediates the mummification behavior of Thitarodes xiaojinensis larvae infected with Ophiocordyceps sinensis.

INTRODUCTION: Parasites can facilitate their own spread and reproduction by manipulating insect hosts behavior, as seen in the interaction between Thitarodes xiaojinensis and Ophiocordyceps sinensis. Infection by O.

High relevance

Snow Fungus · 2024 · Journal Article · Food chemistry

Mechanism on microbial transglutaminase and Tremella fuciformis polysaccharide-mediated modification of lactoferrin: Development of functional food.

Lactoferrin (LF) with various biological functions demonstrates great application potential. However, its application was restricted by its poor gelation and instability..

Immune supportGut & microbiome

High relevance

Snow Fungus · 2024 · Journal Article · Food & function

Metagenomic and transcriptomic profiling of the hypoglycemic and hypotriglyceridemic actions of Tremella fuciformis-derived polysaccharides in high-fat-diet- and streptozotocin-treated mice.

Mushroom polysaccharides have great anti-diabetes potential. The fruiting body of Tremella fuciformis is rich in polysaccharides.

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Lion's Mane · 2024 · Journal Article · Bio Systems

Micro-electrode array recording of extracellular electrical potentials of liquid static surface fermented Hericium erinaceus.

Hericium erinaceus is a basidiomycetes fungus with previously uncharacterised extracellular electrophysiology. Here, we present results of recordings of the electrical potentials of fungal biofilms of this species using microelectrode arrays (MEAs)..