MycoData

This study aimed to enhance the production of mycelium biomass and exopolysaccharides (EPS) of Pleurotus ostreatus in submerged fermentation. Response Surface Methodology (RSM)sought to optimize culture conditions, whereas Artificial Neural Network (ANN)aimed to predict the mycelium biomass and EPS..

Immune support

High relevance

Reishi · 2024 · Journal Article · Journal of food science

Enhancement of exercise-induced fatigue alleviation and liver selenium regulation through in situ nanoselenium synthesis by Lactobacillus rhamnosus cells, empowered by Ganoderma lucidum spore loading.

Given the increasing awareness of the negative effects of fatigue on daily activities, mental health, and quality of life, antifatigue supplements are becoming increasingly popular among consumers. Selenium has been found to have antifatigue potential in high dosage, but may cause toxicity effects to the body..

Energy & fatigueGut & microbiomeLiver support

High relevance

Turkey Tail · 2024 · Journal Article · Journal of biotechnology

Enhancement of the biological activity of hydroxytyrosol through its oxidation by laccase from Trametes versicolor.

The laccase-catalyzed oxidation of hydroxytyrosol (HT) towards the formation of its bioactive oligomer derivatives was investigated. The biocatalytic oligomerization was catalyzed by laccase from Trametes versicolor in aqueous or various water-miscible organic solvents and deep eutectic solvent (DES)-based media..

OncologyEnergy & fatigueSkin & hydration

High relevance

Reishi · 2024 · Journal Article · World J Microbiol Biotechnol

Enhancing high-efficiency breeding and microbial microdroplet cultivation techniques for Ganoderma lucidum

Ganoderma lucidum is known for its bioactive compounds, such as polysaccharides and triterpenoids, which are crucial in food and medicine. However, liquid fermentation encounters challenges in terms of strain differentiation and stability..

Immune supportGut & microbiome

High relevance

Reishi · 2024 · Journal Article · World journal of microbiology & biotechnology

Enhancing high-efficiency breeding and microbial microdroplet cultivation techniques for Ganoderma lucidum.

Immune supportGut & microbiome

High relevance

Niu-Chang-Chih · 2024 · Journal Article · Innovative Food Science and Emerging Technologies

Enhancing submerged fermentation of Antrodia camphorata by low-frequency alternating magnetic field

This work aimed to investigate the impact of low-frequency (30–300 kHz) alternating magnetic field (LF-AMF) on enhancing submerged fermentation of Antrodia camphorata (A. camphorata), a basidiomycete fungus..

Immune supportEnergy & fatigueSkin & hydration

High relevance

Oyster Mushroom · 2024 · Journal Article · Animal feed science and technology

Enhancing the nutritional value of canola meal through solid culture with Pleurotus ostreatus

Canola or rapeseed meal is a source of high-value protein, vitamins, and minerals. However, its feeding application for monogastric animals has been impeded due to the presence of antinutrients and undigestible fiber..

Gut & microbiome

High relevance

Shiitake · 2024 · Journal Article · Heliyon

Enhancing yields of Pleurotus ostreatus and Lentinula edodes mushrooms using water hyacinth (Eichhornia crassipes [Mart.] Solms) supplemented with locally available feedstock as substrate

This study assessed the performance of Pleurotus ostreatus and Lentinula edodes mushrooms on a variety of substrate combinations. Water hyacinth, rice husk, and cow dung were employed as substrates.

Energy & fatigue

High relevance

Shiitake · 2024 · Research Article · Heliyon

Enhancing yields of Pleurotus ostreatus and Lentinula edodes mushrooms using water hyacinth (Eichhornia crassipes [Mart.] Solms) supplemented with locally available feedstock as substrate.

This study assessed the performance of Pleurotus ostreatus and Lentinula edodes mushrooms on a variety of substrate combinations. Water hyacinth, rice husk, and cow dung were employed as substrates.

Energy & fatigue

High relevance

Oyster Mushroom · 2024 · Journal Article · The Science of the total environment

Enrichment characteristics of Cd and Hg and regulation of heavy metal transporter signaling in Pleurotus ostreatus.

Currently, heavy metal pollution has emerged as a global issue. Compared with green plants, edible fungi, significant crops cultivated worldwide, present a greater capacity to accumulate heavy metals (HMs)..

High relevance

Turkey Tail · 2024 · Journal Article · The Science of the total environment

Enzymatic degradation of tetracycline by Trametes versicolor laccase in a fluidized bed reactor.

Laccase from Trametes Versicolor was successfully immobilized on gelatin beads by a crosslinking reaction with glutaraldehyde. Immobilized laccases showed better stability towards pH and temperature than free laccases..

High relevance

Lion's Mane · 2024 · Research Article · Molecules (Basel, Switzerland)

Erinacenones A-L: Twelve New Isoindolinone Alkaloids from the Edible and Medicinal Mushroom Hericium erinaceus.

A total of twelve previously unreported isoindolin-1-one compounds, erinacenones A-L (1-12), were isolated from liquid cultures of the medicinal fungus Hericium erinaceus. Their structures were elucidated based on spectroscopic data analysis..

Oncology

High relevance

Lion's Mane · 2024 · Research Article · Antioxidants (Basel, Switzerland)

Erinacine A-Enriched Hericium erinaceus Mycelium Ethanol Extract Lessens Cellular Damage in Cell and Drosophila Models of Spinocerebellar Ataxia Type 3 by Improvement of Nrf2 Activation.

Spinocerebellar ataxia type 3 (SCA3), caused by the abnormal expansion of polyglutamine (polyQ) in the ataxin-3 protein, is one of the inherited polyQ neurodegenerative diseases that share similar genetic and molecular features..

OncologyCognition & nerves

High relevance

Lion's Mane · 2024 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Erinacine S, a small active component derived from Hericium erinaceus, protects oligodendrocytes and alleviates mood abnormalities in cuprizone-exposed rodents.

Hericium erinaceus mycelium extract (HEM), containing erinacine A (HeA) and erinacine S (HeS), has shown promise in promoting the differentiation of oligodendrocyte precursor cells (OPCs) into mature oligodendrocytes (OLs), crucial for myelin production in the central nervous system (CNS)..

Cognition & nerves

High relevance

Shiitake · 2024 · Preprint · journal metadata

Establishing an Interactive Sequence Database for Shiitake Cultivar Identification

Shiitake mushrooms (Lentinula edodes) hold significant cultural and economic value, particularly in Asia where they are extensively cultivated. The diversification of shiitake cultivars, driven by the need to adapt to various climatic conditions and cultivation methods, has resulted in over 200 distinct cultivars..

High relevance

Maitake · 2024 · Research Article · Frontiers in microbiology

Establishment and application of a SNP molecular identification system in Grifola frondosa.

Germplasm resources of edible mushrooms are essential for the breeding of varieties with improved traits. Analysis of the genetic diversity of Grifola frondosa germplasm resources and clarification of the genetic relationships among strains can provide valuable information for the selection of breeding parents..

High relevance

Oyster Mushroom · 2024 · Journal Article · Journal of agricultural and food chemistry

Exogenous Salicylic Acid Regulates Fruiting Body Development, Secondary Metabolite Accumulation, Cell Wall Integrity, and Endogenous Salicylic Acid Content under Heat Stress in Pleurotus ostreatus.

High-temperature or heat stress (HS) represents a significant environmental challenge that adversely affects crop growth and poses a substantial threat to agricultural production..

Metabolic health

High relevance

Reishi · 2024 · Journal Article · Fitoterapia

Explore the mechanisms of triterpenoids from Ganoderma lucidum in the protection against Alzheimer's disease via microbiota-gut-brain axis with the aid of network pharmacology.

Ganoderma lucidum (Curtis) P. Karst.(G.

Cognition & nervesGut & microbiome

High relevance

Reishi · 2024 · Journal Article · World J Microbiol Biotechnol

Exploring Ganoderma lucidum: morphology, cultivation and market potential

Ganoderma lucidum, known as the “mushroom of immortality,” is a white rot fungus renowned for its medicinal properties, attributed to its bioactive compounds. Although species with similar morphological traits to G..

High relevance

Enoki · 2024 · Journal Article · International journal of biological macromolecules

Extraction of chitin from flammulina velutipes waste: A low-concentration acid pretreatment and aspergillus Niger fermentation approach.

In recent years, with the booming of the edible mushroom industry, chitin production has become increasingly dependent on fungi and other non-traditional sources. Fungal chitin has advantages including superior performance, simpler separation processes, abundant raw materials, and the absence of shellfish allergens..

Energy & fatigueMetabolic health

High relevance

Turkey Tail · 2024 · Journal Article · International journal of biological macromolecules

Fabrication of the carbon paste electrode modified with Trametes versicolor laccase immobilized on carboxyl functionalized multi-walled carbon nanotubes and its application for measurement of dopamine.

Dopamine (DA) shows numerous roles in a wide range of physiological and pathological processes. In this study, an immobilized laccase-derived biosensor was developed for DA detection..

High relevance

Oyster Mushroom · 2024 · Research Article · International journal of molecular sciences

Family Identification and Functional Study of Copper Transporter Genes in Pleurotus ostreatus.

The copper transport (COPT/Ctr) family plays an important role in maintaining metal homeostasis in organisms, and many species rely on Ctrs to achieve transmembrane transport via copper (Cu) uptake. At present, the Ctr family is widely studied in plants..

High relevance

Oyster Mushroom · 2024 · Research Article · Mycoscience

Fermentation of soybeans with Pleurotus cornucopiae and Pleurotus ostreatus increases isoflavone aglycones, total polyphenol content and antioxidant activity.

Edible basidiomycetes are highly active in the oxidative decomposition and polymerisation of polyphenols, and soybeans contain large amounts of isoflavones, which are polyphenol glycosides. Isoflavone aglycones exhibit weak estrogenic activities..

High relevance

Maitake · 2024 · Journal Article · Physiological and Molecular Plant Pathology

First report of bacterial blotch disease caused by Burkholderia gladioli in Grifola frondosa from China

Grifola frondosa has been regarded as healthy food resources for its potentially nutraceutical and pharmaceutical values for centuries. During 2023, a bacterial blotch disease with a 40 % incidence rate was observed in G.

High relevance

Oyster Mushroom · 2024 · Research Article · Foods (Basel, Switzerland)

Fish Fillet Analogue Using Formulation Based on Mushroom (Pleurotus ostreatus) and Enzymatic Treatment: Texture, Sensory, Aromatic Profile and Physicochemical Characterization.

The growing demand for alternative sources of non-animal proteins has stimulated research in this area. Mushrooms show potential in the innovation of plant-based food products..

Skin & hydration

High relevance

Reishi · 2024 · Journal Article · Fitoterapia

Five undescribed meroterpenoids from Ganoderma lucidum and their inhibitory activities against renal fibrosis.

Five undescribed meroterpenoids, baosglucidnes A - E (1-5), were isolated from the fruiting bodies of Ganoderma lucidum. Among them, baosglucidne B (2) as a racemic mixture was obtained.

Skin & hydration

High relevance

Shiitake · 2024 · Journal Article · International journal of biological macromolecules

Fractionation, characterization, and assessment of nutritional and immunostimulatory protein-rich polysaccharide-protein complexes isolated from Lentinula edodes mushroom.

This study aimed to fractionate and characterize the protein-rich polysaccharide-protein (PSP) complexes from a well-known edible mushroom, Lentinula edodes, and assess their nutritional and immunostimulatory properties..

Immune support

High relevance

Enoki · 2024 · Journal Article · Journal of agricultural and food chemistry

Functional Characterization of Sesquiterpene Synthases and P450 Enzymes in Flammulina velutipes for Biosynthesis of Spiro [4.5] Decane Terpene.

Flammulina velutipes, a popular edible mushroom, contains sesquiterpenes with potential health benefits. We characterized 12 sesquiterpene synthases and one P450 enzyme in F.

High relevance

Reishi · 2024 · Research Article · Journal of animal science

Functional properties of Ganoderma lucidum supplementation in canine nutrition.

Ganoderma lucidum (GL) is a mushroom that has been widely used in Asia for its immunostimulatory and anti-inflammatory capacity, which has been hypothesized to be attributed mainly to the recognition of its cell-surface patterns by cells of the immune system present in the gastrointestinal tract, resulting in a….

Immune supportCognition & nervesGut & microbiomeLiver support

High relevance

Turkey Tail · 2024 · Journal Article · Journal of natural products

Fungal Coculture of Herpotrichia sp. and Trametes versicolor Induces Production of Diverse Metabolites with Anti-Parkinson's Neuroprotective Activity.

Co-cultivation of isopod-associated fungi Herpotrichia sp. SF09 and Trametes versicolor SF09A led to the reciprocal induction of thirteen new compounds (1-7 and 9-13) with diverse architectures..

Cognition & nerves

High relevance

Reishi · 2024 · Research Article · Pharmaceuticals (Basel, Switzerland)

Ganoderma lucidum (Curtis) P. Karst. Immunomodulatory Protein Has the Potential to Improve the Prognosis of Breast Cancer Through the Regulation of Key Prognosis-Related Genes.

Background/Objectives: Breast cancer in women is the most commonly diagnosed and most malignant tumor. Although luminal A breast cancer (LumA) has a relatively better prognosis, it still has a persistent pattern of recurrence.

OncologyImmune support

High relevance

Reishi · 2024 · Research Article · Medical principles and practice: international journal of the Kuwait University, Health Science Centre

Ganoderma lucidum and Hypericum perforatum Exhibit Anti-Inflammatory, Antioxidant, and Anti-Androgen Effect in Rat Model of Experimental Polycystic Ovarian Syndrome.

OBJECTIVE: Chronic inflammation is considered to be of key importance in the pathogenesis of polycystic ovarian syndrome (PCOS). Ganoderma lucidum polysaccharide (GLP) and Hypericum perforatum (HP) have been reported to have anti-inflammatory and antioxidant activities..

OncologyImmune supportMetabolic health

High relevance

Reishi · 2024 · Research Article · Food chemistry: X

Ganoderma lucidum driven fermentation of Rosa roxburghii pomace: Effects on noodle physicochemical properties, digestion, and gut microbiota.

Rosa roxburghii pomace (RRP) is a high dietary fiber byproduct that is underutilized. This study investigated the effects of Ganoderma lucidum fermented Rosa roxburghii pomace (FRRP) on noodle cooking characteristics, texture, structure, in vitro digestion, and fermentation..

Immune supportMetabolic healthGut & microbiome

High relevance

Reishi · 2024 · Research Article · iScience

Ganoderma lucidum extract attenuates corticotropin-releasing hormone-induced cellular senescence in human hair follicle cells.

Corticotropin-releasing hormone (CRH) is a key mediator in stress-induced hair growth inhibition. Here, we investigated the impact of stress-induced senescence and evaluated the potential of Ganoderma lucidum (GL) extract in mitigating CRH-induced senescence in human hair follicle cells (hHFCs)..

Energy & fatigue

High relevance

Reishi · 2024 · Research Article · Chinese medicine

Ganoderma lucidum polysaccharide ameliorates cholesterol gallstone formation by modulating cholesterol and bile acid metabolism in an FXR-dependent manner.

BACKGROUND: Cholesterol gallstone (CG) disease is a worldwide common disease characterized by cholesterol supersaturation in gallbladder bile. Ganoderma lucidum polysaccharide (GLP) has been shown to possess various beneficial effects against metabolic disorders..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Reishi · 2024 · Journal Article · International journal of biological macromolecules

Ganoderma lucidum polysaccharide hydrogel accelerates diabetic wound healing by regulating macrophage polarization.

Impaired macrophage polarization or the high levels of reactive oxygen species (ROS) produced by high glucose conditions and bacterial infection are the primary factors that make healing diabetic wounds difficult..

Immune supportEnergy & fatigueMetabolic healthSkin & hydration

High relevance

Reishi · 2024 · Research Article · Biomedicines

Ganoderma lucidum Polysaccharide Peptide Alleviates Cyclophosphamide-Induced Male Reproductive Injury by Reducing Oxidative Stress and Apoptosis.

Chemotherapy is an important factor leading to male infertility. It is crucial to discover safe and effective treatments to prevent male reproductive injury caused by chemotherapy.

OncologyImmune support

High relevance

Reishi · 2024 · Journal Article · Journal of agricultural and food chemistry

Ganoderma lucidum Polysaccharide Supplementation Significantly Activates T-Cell-Mediated Antitumor Immunity and Enhances Anti-PD-1 Immunotherapy Efficacy in Colorectal Cancer.

Ganoderma lucidum polysaccharide (GLP) is a prebiotic with immunomodulatory effects. However, the therapeutic potential of GLP in tumor immunotherapy has not been fully explored, especially in T cell-mediated antitumor immunity..

OncologyImmune supportGut & microbiome

High relevance

Reishi · 2024 · Research Article · Nutrients

Ganoderma lucidum Polysaccharides Ameliorate Acetaminophen-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Apoptosis along the Nrf2 Pathway.

The excessive employment of acetaminophen (APAP) is capable of generating oxidative stress and apoptosis, which ultimately result in acute liver injury (ALI). Ganoderma lucidum polysaccharides (GLPs) exhibit hepatoprotective activity, yet the protective impact and potential mechanism of GLPs in relation to….

OncologyImmune supportLiver support

High relevance

Reishi · 2024 · Research Article · Antioxidants (Basel, Switzerland)

Ganoderma lucidum Spore Powder Alleviates Metabolic-Associated Fatty Liver Disease by Improving Lipid Accumulation and Oxidative Stress via Autophagy.

Lipid accumulation and oxidative stress, which could be improved by autophagy, are the "hits" of metabolic-associated fatty liver disease (MAFLD). Ganoderma lucidum spore powder (GLSP) has the effect of improving liver function..

Energy & fatigueMetabolic healthLiver support

High relevance

Reishi · 2024 · Journal Article · International journal of biological macromolecules

Ganoderma lucidum spores-derived particulate β-glucan treatment improves antitumor response by regulating myeloid-derived suppressor cells in triple-negative breast cancer.

Granular β-1,3-glucan extracted from the wall of Ganoderma lucidum spores, named GPG, is a bioregulator. In this study, we investigated the structural, thermal, and other physical properties of GPG.

OncologyImmune support

High relevance

Reishi · 2024 · Journal Article · Molecules (Basel, Switzerland)

Ganoderma lucidum-Derived Meroterpenoids Show Anti-Inflammatory Activity In Vitro.

Ganoderma lucidum, known as the "herb of spiritual potency", is used for the treatment and prevention of various diseases, but the responsible constituents for its therapeutic effects are largely unknown. For the purpose of obtaining insight into the chemical and biological profiling of meroterpenoids in G..

Immune support

High relevance

Reishi · 2024 · Journal Article · Heliyon

Ganoderma lucidum: Insight into antimicrobial and antioxidant properties with development of secondary metabolites

Ganoderma lucidum is a versatile mushroom. Polysaccharides and triterpenoids are the major bioactive compounds and have been used as traditional medicinal mushrooms since ancient times.

OncologyImmune supportMetabolic health

High relevance

Reishi · 2024 · Journal Article · Phytochemistry

Ganospirones A-G, seven undescribed spiro-meroterpenoids from Ganoderma lucidum and their biological activities.

Ganoderma lucidum, a medicinal mushroom with a long history in traditional Chinese medicine, is widely used for chronic diseases. Ganospirones A-G (1-7), seven pairs of undescribed spiro-meroterpenoids, were isolated from the fruiting bodies of G.

Immune support

High relevance

Shiitake · 2024 · Research Article · Mycoscience

Gene expression analysis for stem browning in the mushroom Lentinula edodes.

The mushroom Lentinula edodes, is consumed worldwide and has high industrial value because of its rich content of bioactive compounds such as ergothioneine and eritadenine. Currently, mainstream artificial cultivation methods for this mushroom typically use synthetic logs..

High relevance

Shiitake · 2024 · Research Article · Journal of fungi (Basel, Switzerland)

Genome Sequencing of Lentinula edodes Revealed a Genomic Variant Block Associated with a Thermo-Tolerant Trait in Fruit Body Formation.

The formation of multicellular fruiting bodies in basidiomycete mushrooms is a crucial developmental process for sexual reproduction and subsequent spore development. Temperature is one of the most critical factors influencing the phase transition for mushroom reproduction..

High relevance

Zhu Ling · 2024 · Research Article · Journal of fungi (Basel, Switzerland)

Genome Sequencing Providing Molecular Evidence of Tetrapolar Mating System and Heterothallic Life Cycle for Edible and Medicinal Mushroom Polyporus umbellatus Fr.

Polyporus umbellatus is a species whose sclerotia have been extensively employed in traditional Chinese medicine, which has diuretic, antitumor, anticancer, and immune system enhancement properties. However, prolonged asexual reproduction has resulted in significant homogenization and degeneration of seed sclerotia..

OncologyImmune support

High relevance

Reishi · 2024 · Journal Article · Free radical biology & medicine

Glsirt1-mediated deacetylation of GlCAT regulates intracellular ROS levels, affecting ganoderic acid biosynthesis in Ganoderma lucidum.

Lysine acetylation is a reversible, dynamic protein modification regulated by lysine acetyltransferases and deacetylases. However, in Basidiomycetes, the extent of lysine acetylation of nonhistone proteins remains largely unknown..

Energy & fatigue

High relevance

Reishi · 2024 · Research Article · Journal of pharmacy & bioallied sciences

Green Synthesis of Ganoderma Lucidum-Mediated Silver Nanoparticles and its Microbial Activity against Oral Pathogenic Microbes: An In Vitro Study.

Nanotechnology is developing into a fast-expanding discipline with applications in science and technology, and nanostructures are a crucial research tool in many fields..

Immune support

High relevance

Maitake · 2024 · Journal Article · Food Research International

Grifola frondosa extract as a fetal bovine serum supplement for the culture of bovine muscle satellite cells under low serum conditions

Expensive fetal bovine serum (FBS) is a major obstacle to the production of cultivated meat. However, because FBS substitutes do not sufficiently induce cell proliferation, a good alternative is to reduce the amount of FBS and use ingestible additives to promote cell proliferation..

Energy & fatigue