MycoData

Reishi · 2024 · Research Article · Molecules (Basel, Switzerland)

The Anti-Melanogenic Effects of Ganodermanontriol from the Medicinal Mushroom Ganoderma lucidum through the Regulation of the CREB and MAPK Signaling Pathways in B16F10 Cells.

Ganoderma lucidum, a member of the Basidiomycetes family, is attracting attention for its medicinal potential due to its biological activity and the presence of numerous bioactive compounds..

Immune supportGut & microbiomeSkin & hydration

Snow Fungus · 2024 · Research Article · Foods (Basel, Switzerland)

The Effects of Tremella fuciformis Polysaccharide on the Physicochemical, Multiscale Structure and Digestive Properties of Cyperus esculentus Starch.

In this study, we have investigated the effects of Tremella fuciformis polysaccharide (TP) on the pasting, rheological, structural and in vitro digestive properties of Cyperus esculentus starch (CS)..

Energy & fatigueMetabolic healthSkin & hydration

Shiitake · 2024 · Journal Article · Journal of agricultural and food chemistry

Transcriptomic Communication between Nucleus and Mitochondria during the Browning Process of Lentinula edodes.

To explore the reason for cytoplasmic replacement's significant effect on browning, transcriptomic data of nuclear (N) and mitochondrial (M) mRNAs and long noncoding RNAs (lncRNAs) in L808 and two cytoplasmic hybrids (cybrids) (L808-A2 and L808-B) of Lentinula edodes at three different culturing times (80, 100, and….

Almond Mushroom · 2024 · Journal Article · International journal of biological macromolecules

Troxerutin associated with Agaricus blazei Murill polysaccharides in films improves full-thickness wound healing.

The present study aimed to associate troxerutin (TRX) with polysaccharides from Agaricus blazei Murill mushroom (PolyAb) in alginate/PVA films and evaluate their effect on wound healing..

OncologyImmune supportLiver supportSkin & hydration

Zhu Ling · 2021 · Review · International journal of biological macromolecules

Polysaccharides from Polyporus umbellatus: A review on their extraction, modification, structure, and bioactivities.

Polyporus umbellatus (Pers.) Fries, a well-known medicinal fungus, has been reported to exhibit important functions of diuresis and dampness infiltration in traditional Chinese Medicine. Accumulating evidences have demonstrated that the P..

OncologyImmune supportMetabolic healthSkin & hydration

Cordyceps · 2025 · Research Article · Scientific reports

Quantitative detection of β-glucans in Cordyceps species using a validated Congo red assay.

β-Glucan is extensively utilized in the food industry for its functional benefits, including blood glucose and lipid regulation, enhanced food texture, and a prolonged shelf life..

Cognition & nervesEnergy & fatigueSkin & hydration

Shiitake · 2025 · Research Article · PloS one

Sustainable memristors from shiitake mycelium for high-frequency bioelectronics.

Neuromorphic computing, inspired by the structure of the brain, offers advantages in parallel processing, memory storage, and energy efficiency. However, current semiconductor-based neuromorphic chips require rare-earth materials and costly fabrication processes, whereas neural organoids need complex bioreactor….

OncologyImmune supportMetabolic healthSkin & hydration

Chaga · 2023 · Review · Frontiers in pharmacology

Chaga mushroom: a super-fungus with countless facets and untapped potential.

Inonotus obliquus (Chaga mushroom) is an inexpensive fungus with a broad range of traditional and medicinal applications. These applications include therapy for breast, cervix, and skin cancers, as well as treating diabetes..

Cognition & nervesSkin & hydration

Almond Mushroom · 2023 · Randomized Controlled Trial · Scandinavian journal of psychology

Cognitive behavioral therapy (CBT) plus attention bias modification (ABM) reduces anxiety sensitivity and depressive symptoms in panic disorder: A pilot randomized trial.

BACKGROUND: Cognitive bias theories propose that reducing threat hypervigilance in mental disorders can augment cognitive behavioral therapy (CBT) outcomes. However, no studies have tested whether adding attention bias modification (ABM) can effectively enhance CBT's effects on anxiety sensitivity (AS),….

Metabolic healthSkin & hydration

Shiitake · 2021 · Randomized Controlled Trial · International journal of medicinal mushrooms

Effects of Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), Bars on Lipid and Antioxidant Profiles in Individuals with Borderline High Cholesterol: A Double-Blind Randomized Clinical Trial.

Shiitake (Lentinus edodes) is a culinary-medicinal mushroom that has low lipid content and is rich in protein, fiber, minerals, vitamins, antioxidant compounds, and β-glucans. We assessed the effects of L..

Cordyceps · 2022 · Comparative Study · Pharmaceutical biology

Comparison of chemical profiles, antioxidation, inhibition of skin extracellular matrix degradation, and anti-tyrosinase activity between mycelium and fruiting body of Cordyceps militaris and Isaria tenuipes.

CONTEXT: Cordyceps militaris and Isaria tenuipes (Cordycipitaceae) are high-value fungi that are used for health-promoting food supplements. Since laboratory cultivation has begun for these fungi, increased output has been achieved..

Skin & hydrationRespiratory

Oyster Mushroom · 2021 · Case Reports · International journal of occupational medicine and environmental health

A case of anaphylactic reaction following oyster mushroom (Pleurotus ostreatus) inhalation.

Oyster mushroom (Pleurotus ostreatus) is one of the most widely consumed mushrooms in the world. Its spores are highly potent allergens, but their main allergen, Pleo, has so far been very rarely reported.

Immune supportCognition & nervesEnergy & fatigueSkin & hydration

Almond Mushroom · 2021 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

Agaricus blazei polypeptide exerts a protective effect on D-galactose-induced aging mice via the Keap1/Nrf2/ARE and P53/Trim32 signaling pathways.

This experiment mainly optimized the extraction technology of Agaricus blazei polypeptide (ABp) and evaluated its protective effect on aging mice. In this study, a novel single component, the M is 3 kD, was isolated and purified from Agaricus blazei.

Reishi · 2021 · Research Support, Non U.S. Gov'T · Integrative cancer therapies

Sporoderm-Removed Ganoderma lucidum Spore Powder May Suppress the Proliferation, Migration, and Invasion of Esophageal Squamous Cell Carcinoma Cells Through PI3K/AKT/mTOR and Erk Pathway.

Tumor metastasis is a key factor of therapeutic failure in tumor patients, but the underlying molecular mechanism remains to be explored and novel effective curative strategies are urgently required..

OncologySkin & hydration

Shiitake · 2017 · Systematic Review · International journal of dermatology

Clinical features of shiitake dermatitis: a systematic review.

Shiitake dermatitis is a rare cutaneous reaction to lentinan, a polysaccharide component in the cell walls of shiitake mushrooms (Lentinula edodes). Herein, we systematically review the case report and case series English-language literature on shiitake dermatitis, which refers to a total of 50 patients (38 males, 12….

Chaga · 2020 · Preprint · journal metadata

Genoprotective effects of Chaga mushroom ( Inonotus obliquus ) polysaccharides in UVB-exposed embryonic zebrafish ( Danio rerio ) through coordinated expression of DNA repair genes

Background Chaga mushroom (Inonotus obliquus) is one of the most promising antioxidants with incredible health-promoting effects. Chaga polysaccharides (IOP) have been reported to enhance immune response and alleviate oxidative stress during development..

Chaga · 2020 · Preprint · journal metadata

Inonotus Obliquus Extracts Decreased Expression of MMP1 mRNA via JNK-AP-1 Axis

In present study, the effect of Inonotus Obliquus extracts used in traditional medicine was investigated on the expression of matrix metalloproteinases-1 (MMP-1) in the normal human dermal fibroblasts..

Chaga · 2018 · Preprint · journal metadata

Inonotus Obliquus extracts as an inhibitor of α-MSH-induced melanogenesis in B16F10 mouse melanoma cells

Melanogenesis is a biosynthetic pathway for producing of the pigment melanin in human skin. Tyrosinase, a key enzyme, catalyzing is the first step in melanogenesis and the downregulation of the tyrosinase enzyme activity is the most reported method for anti-melanogenesis..

OncologySkin & hydration

Cognition & nervesSkin & hydration

Shiitake · 2023 · Preprint · journal metadata

Disentangling the Tissue-Specific Variations of Volatile Flavor Profiles of Lentinula edodes Fruiting Body

For Lentinula edodes, its characteristic flavor is the key determinant for consumer pref-erences. However, the tissue-specific volatile flavor variations of the fruiting body have been overlooked..

Reishi · 2023 · Preprint · journal metadata

Hydrogen sulfide maintains redox homeostasis and suppresses ganoderic acids biosynthesis under heat stress via S-sulfhydrating thioredoxin 1 in Ganoderma lucidum

Abstract Hydrogen sulfide (H 2 S) is considered to be a novel gaseous signalling molecule with multiple physiological functions. Recently, the identification of sulfhydrated proteins has become a new hotspot in the analysis of the underlying mechanism of H 2 S..

Immune supportEnergy & fatigueMetabolic healthSkin & hydration

Chaga · 2023 · Preprint · journal metadata

Protective effect of Inonotus obliquus polysaccharide on fibroblasts after MGO-induced nonenzymatic glycation

Abstract Background Nonenzymatic glycation of fibroblasts causes functional downregulation and behavioral disorders in skin. Methods To investigate the effect of Inonotus obliquus on the nonenzymatic glycation of skin, we examined advanced glycation end product (AGE) inhibition by four extract fractions: n-butanol,….

Chaga · 2021 · Published Erratum · Heliyon

Corrigendum to "Chaga mushroom (Inonotus obliquus) polysaccharides exhibit genoprotective effects in UVB-exposed embryonic zebrafish (Danio rerio) through coordinated expression of DNA repair genes" [Heliyon 7 (2) (February 2021) Article e06003].

[This corrects the article DOI: 10.1016/j.heliyon.2021.e06003.]..

Chaga · 2021 · Preprint · journal metadata

Genome Sequencing of Inonotus Obliquus Reveals Insights Into Candidate Genes Involved In Secondary Metabolite Biosynthesis

Background: Inonotus obliquus is an important edible and medicinal mushroom that was shown to have many pharmacological activities in preclinical trials, including anti-inflammatory, antitumor, immunomodulatory, and antioxidant effects..

Cordyceps · 2020 · Research Article · Physical activity and nutrition

Anti-atopic dermatitis properties of Cordyceps militaris on TNFα/IFNγ-stimulated HaCaT cells and experimentally induced atopic dermatitis in mice.

PURPOSE: This study evaluated the anti-atopic dermatitis (AD) properties of Cordyceps militaris (CM) aqueous extract in keratinocytes in vitro and in vivo. We investigated the nutraceutical composition of the CM extract, including its protein, carbohydrate, and selected phytochemical content..

Cordyceps · 2020 · Research Article · Mycobiology

Antithrombotic and Antiplatelet Effects of Cordyceps militaris.

Cordyceps is a genus of ascomycete fungi and is well known as one of the important medical fungi in Chinese, Korea, and other Asian countries, because of its various beneficial effects on human health..

Shiitake · 2020 · Journal Article · Journal of agricultural and food chemistry

Changes in the Key Aroma Compounds of Raw Shiitake Mushrooms (Lentinula edodes) Induced by Pan-Frying As Well As by Rehydration of Dry Mushrooms.

Application of the aroma extract dilution analysis (AEDA) on an extract/distillate from raw shiitake mushrooms revealed 32 odorants among which 3-(methylthio)propanal (cooked potato), 1-octen-3-one, and 1-octen-3-ol (both mushroom-like) showed the highest flavor dilution (FD) factors..

Cordyceps · 2020 · Research Article · Molecules (Basel, Switzerland)

Cordyceps militaris Fungus Extracts-Mediated Nanoemulsion for Improvement Antioxidant, Antimicrobial, and Anti-Inflammatory Activities.

This study aimed to produce and optimize a Cordyceps militaris-based oil-in-water (O/W) nanoemulsion (NE) encapsulated in sea buckthorn oil (SBT) using an ultrasonication process. Herein, a nonionic surfactant (Tween 80) and chitosan cosurfactant were used as emulsifying agents..

Gut & microbiomeSkin & hydration

Oyster Mushroom · 2020 · Research Article · Foods (Basel, Switzerland)

Effects of Various Drying Methods on Some Physico-Chemical Properties and the Antioxidant Profile and ACE Inhibition Activity of Oyster Mushrooms (Pleurotus Ostreatus).

In food biotechnology, Pleurotus ostreatus is of great interest as a source of natural antioxidants and angiotensin-converting enzyme (ACE) inhibitors. However, research in this area has not yet been completed..

OncologyLiver supportSkin & hydration

Cordyceps · 2020 · Research Article · Nanomaterials (Basel, Switzerland)

Enhancement of Chemical Stability and Dermal Delivery of Cordyceps militaris Extracts by Nanoemulsion.

This study aimed to develop nanoemulsions for enhancing chemical stability and dermal delivery of Cordyceps militaris extracts. C.

Reishi · 2020 · Research Article · Pharmaceuticals (Basel, Switzerland)

Ganoderma lucidum Ethanol Extracts Enhance Re-Epithelialization and Prevent Keratinocytes from Free-Radical Injury.

Ganoderma lucidum or Reishi is recognized as the most potent adaptogen present in nature, and its anti-inflammatory, antioxidant, immunomodulatory and anticancer activities are well known. Moreover, lately, there has been an increasing interest from pharmaceutical companies in antiaging G..

Oyster Mushroom · 2020 · Research Article · ACS omega

Ultraviolet Irradiation Increased the Concentration of Vitamin D2 and Decreased the Concentration of Ergosterol in Shiitake Mushroom (Lentinus edodes) and Oyster Mushroom (Pleurotus ostreatus) Powder in Ethanol Suspension.

Vitamin D deficiency is a serious global health problem. Edible mushrooms are a good source of vitamin D for human health.

Almond Mushroom · 2019 · Journal Article · Food & function

Agaricus blazei Murrill from Brazil: an ingredient for nutraceutical and cosmeceutical applications.

Operations for sorting mushrooms at the industrial level usually generate large amounts of bio-residues not conforming to strict morphological criteria for commercial purposes, even though their biological content is not compromised..

Shiitake · 2019 · Journal Article · Food chemistry

Effects of high-temperature pre-drying on the quality of air-dried shiitake mushrooms (Lentinula edodes).

We investigated the relationship between the pre-drying temperature and overall quality of dried shiitake mushrooms (Lentinula edodes). Results showed that high-temperature pre-drying significantly increased the rehydration ratio and hardness of dried shiitake mushrooms, but decreased the degree of shrinkage, degree….

Cordyceps · 2019 · Journal Article · Journal of food processing and preservation

Effects of superfine grinding on the properties and qualities of Cordyceps militaris and its spent substrate

The main purpose of this study is to study the effect of superfine grinding (SG) technology on the physicochemical properties of Cordyceps militaris (CM) and its spent substrate (SS)..

Energy & fatigueSkin & hydration

Oyster Mushroom · 2019 · Research Article · Saudi journal of biological sciences

Impact of the natural resource of UVB on the content of vitamin D2 in oyster mushroom (Pleurotus ostreatus) under subtropical settings.

Vitamin D deficiency is a pandemic problem. Non-animal source of vitamin D is obtained from edible mushrooms.

Chaga · 2019 · Journal Article · Journal of natural medicines

Lanostane-type triterpenes from the sclerotium of Inonotus obliquus (Chaga mushrooms) as proproliferative agents on human follicle dermal papilla cells.

Chaga mushrooms, the sclerotium of Inonotus obliquus, have been used in Mongolia as a traditional hair shampoo to maintain healthy hair. Bioassay-guided fractionations of the extract of Chaga mushrooms using a proliferation assay on human follicle dermal papilla cells (HFDPCs) gave five lanostane-type triterpenes….

Gut & microbiomeSkin & hydration

Chaga · 2019 · Research Article · Biomolecules

Melanins of Inonotus Obliquus: Bifidogenic and Antioxidant Properties.

Extracts and melanins from Inonotus obliquus are widely used in medicine due to their high antioxidant properties. This study is dedicated to define the influence of the physicochemical and antioxidant properties of Inonotus obliquus melanins and their bifidogenic effects on Bifidobacterium bifidum 1 and….

Metabolic healthSkin & hydration

Cordyceps · 2019 · Journal Article · Journal of microbiology (Seoul, Korea)

Metabolomic profiling reveals enrichment of cordycepin in senescence process of Cordyceps militaris fruit bodies.

Cordyceps militaris is a species of Cordyceps that is classified in the Cordycipitaceae family and is well known in East Asia as a traditional medicinal mushroom. Its artificial fruit body has been widely cultivated for commercial use in cosmetics, functional food, and medicine..

Cordyceps · 2019 · Journal Article · Applied microbiology and biotechnology

Purification and structural characterization of a novel natural pigment: cordycepene from edible and medicinal mushroom Cordyceps militaris.

In the present work, a novel cordycepic pigment was successfully isolated and identified from Cordyceps militaris, as well as named as cordycepene (C14H17N1O4), according to the long unsaturated conjugated polyene structural characteristic..

Energy & fatigueSkin & hydration

King Oyster · 2019 · Journal Article · Food chemistry

The main factors inducing postharvest lignification in king oyster mushrooms (Pleurotus eryngii): Wounding and ROS-mediated senescence.

This study was the first investigation into the main inducers of two lignifications by examining the changes of physicochemical properties and gene expression in king oyster mushrooms, under different conditions, during 21 days of storage..

Lion's Mane · 2019 · Journal Article · International journal of medicinal mushrooms

Therapeutic Effect and Potential Mechanisms of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), Mycelia in Submerged Culture on Ethanol-Induced Chronic Gastric Injury.

Hericium erinaceus (HE) is an edible and medicinal mushroom traditionally used for the treatment of gastric injury in clinical practice. However, scientific evidence of its pharmacological activities has not yet been revealed..

Energy & fatigueMetabolic healthSkin & hydration

Enoki · 2019 · Journal Article · International journal of medicinal mushrooms

Wound Healing Activity of a Skin Substitute from Residues of Culinary-Medicinal Winter Mushroom Flammulina velutipes (Agaricomycetes) Cultivation.

A skin substitute TG05 obtained from residues of the culinary-medicinal mushroom Flammulina velutipes cultivation process was developed in this study for the first time..

Immune supportMetabolic healthSkin & hydration

Oyster Mushroom · 2018 · Journal Article · Voprosy pitaniia

[The influence of the drying method for food properties and hypolidemic potential of oyster mushrooms (Pleurotus ostreatus)].

The aim of this research was to study the influence of two drying methods: freeze-drying sublimation and dry-air drying on the selected nutritional properties and hypolipidemic potential of fruiting bodies of oyster mushroom (Pleurotus ostreatus)..

OncologyEnergy & fatigueLiver supportSkin & hydration

Cordyceps · 2018 · Research Article · Oncology letters

Cordyceps militaris fraction inhibits the invasion and metastasis of lung cancer cells through the protein kinase B/glycogen synthase kinase 3β/β-catenin signaling pathway.

Cordyceps militaris is widely used as a traditional Chinese medicine health supplement, and is also used in the development of anticancer agents. In our previous studies, it was revealed that C..

Cordyceps · 2018 · Journal Article · International journal of medicinal mushrooms

Cosmetic and Skincare Benefits of Cultivated Mycelia from the Chinese Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycetes).

Mushrooms are potential sources of novel natural cosmeceutical ingredients. This study was conducted to evaluate the cosmetic (skincare) benefits of the valuable medicinal species Ophiocordyceps sinensis (=Cordyceps sinensis).

Immune supportEnergy & fatigueGut & microbiomeSkin & hydration

King Oyster · 2018 · Journal Article · Fish & shellfish immunology

Dietary administration of eryngii mushroom (Pleurotus eryngii) powder on haemato-immunological responses, bactericidal activity of skin mucus and growth performance of koi carp fingerlings (Cyprinus carpio koi).

The aim of present study was to evaluate the effects of edible eryngii mushroom powder, Pleurotus eryngii (PE), for 63 days on haematological parameters, the serum immune responses, skin mucus, bactericidal activity, stress resistance, growth performance and digestive enzyme activities of Koi carp fingerlings….

Immune supportMetabolic healthSkin & hydration

Enoki · 2018 · Journal Article · International journal of food science & technology

Enzymatic hydrolysis combined with high‐pressure homogenisation for the preparation of polysaccharide‐based nanoparticles from the by‐product of Flammulina velutipes

In this study, protease, α‐amylase and 5‰ β‐glucanase enzymolysis in combination with high‐pressure homogenisation were used for the preparation of polysaccharide‐based nanoparticles from Flammulina velutipes stipes, respectively, named FNP‐1, FNP‐2 and FNP‐3, and the nanoparticles were subsequently characterised..

Energy & fatigueSkin & hydration

Turkey Tail · 2018 · Journal Article · Journal of biotechnology

Extracellular biosynthesis of biocompatible cadmium sulfide quantum dots using Trametes versicolor.

Quantum dots are important fluorescent semiconductor nano-crystals with distinguished electrical and optical properties and have gained great interest in many fields..

Lion's Mane · 2018 · Journal Article · Carbohydrate polymers

Gastroprotective activity of polysaccharide from Hericium erinaceus against ethanol-induced gastric mucosal lesion and pylorus ligation-induced gastric ulcer, and its antioxidant activities.

The gastroprotective activity of Hericium erinaceus polysaccharide was investigated in rats. The antioxidant activities were also evaluated.