MycoData

The aim of this study was to estimate the hydrolytic degree and antioxidant activity of purified casein characterised by different haplotypes (αₛ₁‐, β‐ and k‐casein) after in vitro digestion with two different enzymatic systems: pepsin from porcine gastric mucosa (EP) and a crude enzymatic extract from the edible….

Gut & microbiome

High relevance

Lion's Mane · 2020 · Journal Article · Planta medica

Identification and α-Glucosidase Inhibitory Activity of Meroterpenoids from Hericium erinaceus.

Hericium erinaceus is a very popular edible and medicinal mushroom used for the treatment of enervation and gastrointestinal diseases in Eastern Asia. Chemical investigation on the fruiting body of Hericium erinaceus led to the isolation of 4 new (1: - 4: ) and 10 known meroterpenoids (5: - 14: )..

Metabolic healthGut & microbiome

High relevance

Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms

Immunomodulatory Properties of Water-Soluble Polysaccharides Extracted from the Fruiting Body of Chinese Caterpillar Mushroom, Ophiocordyceps sinensis Cultivar OCS02® (Ascomycetes).

Ophiocordyceps sinensis (=Cordyceps sinensis) has been known for its various medicinal properties, in particular immunomodulatory activities associated with its polysaccharides. In this study, the fruiting body of O.

Immune supportMetabolic health

High relevance

King Oyster · 2020 · Research Article · Food science & nutrition

Impact of mushroom (Pleurotus eryngii) flour upon quality attributes of wheat dough and functional cookies-baked products.

The objective of this study was to create a healthier version of a commonly consumed baked food (cookies) by replacing some of the wheat flour with a nutraceutical-rich mushroom flour..

High relevance

Cordyceps · 2020 · Research Article · Sensors (Basel, Switzerland)

Implementation and Performance Evaluation of Integrated Wireless MultiSensor Module for Aseptic Incubator of Cordyceps militaris.

This paper originally proposes a wireless multisensor module with illuminance, temperature, relative humidity (RH) and carbon dioxide (CO2) sensors in an aseptic jar incubator for a solid-state fermentation (SSF) of Cordyceps militaris culture..

Energy & fatigueRespiratory

High relevance

King Oyster · 2020 · Journal Article · Food Hydrocolloids

In vitro digestion and cellular antioxidant activity of β-carotene-loaded emulsion stabilized by soy protein isolate-Pleurotus eryngii polysaccharide conjugates

β-Carotene is a natural fat-soluble antioxidant, while the poor oral bioavailability of β-carotene restricts its application for functional foods. To overcome this barrier, a stable oil-in-water emulsion was structured to effectively deliver β-carotene..

Immune supportEnergy & fatigueGut & microbiomeLiver support

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Oyster Mushroom · 2020 · Journal Article · Nutricion hospitalaria

In vivo assessment of the protection conferred by β-glucans from Pleurotus ostreatus against the harmful effects of acrylamide intake (Part I).

Introduction: acrylamide is formed in food through Maillard's reaction during thermal processing, and has been shown to be neurotoxic in humans, and a possible carcinogen. Studies have shown that β-glucans from Pleurotus ostreatus have diverse biological properties such as antioxidant and anticancer activities..

OncologyCognition & nervesLiver support

High relevance

Oyster Mushroom · 2020 · Journal Article · Nutricion hospitalaria

In-vivo assessment of the protection of β-glucans of Pleurotus ostreatus against oxidative stress caused by acrylamide intake (part II).

Introduction: in April 2002, the National Food Authority of Sweden published a study in which the presence of a carcinogen was reported for the first time in experimental animals, and was identified as acrylamide..

OncologyCognition & nervesLiver support

High relevance

Cordyceps · 2020 · Research Article · Frontiers in microbiology

Infection of Ophiocordyceps sinensis Fungus Causes Dramatic Changes in the Microbiota of Its Thitarodes Host.

The Chinese cordyceps is a unique and valuable parasitic complex of Thitarodes/Hepialus ghost moths and the Ophiocordyceps sinensis fungus for medicine and health foods from the Tibetan Plateau..

Gut & microbiome

High relevance

Oyster Mushroom · 2020 · Research Article · Journal of fungi (Basel, Switzerland)

Influence of Calcium Silicate on the Chemical Properties of Pleurotus ostreatus var. florida (Jacq.) P. Kumm.

Supplementation of mushroom substrates has been linked to a higher resistance against insect pests, although few studies show the impact of this supplementation on the different agronomical parameters of mushrooms or even their chemical composition..

High relevance

Maitake · 2020 · Research Article · BioMed research international

Influence of Maitake (Grifola frondosa) Particle Sizes on Human Mesenchymal Stem Cells and In Vivo Evaluation of Their Therapeutic Potential.

Maitake (Grifola frondosa) mushroom has received an enormous amount of attention as a dietary supplement due to its high nutritional values. The particle sizes of G.

Immune support

High relevance

Chaga · 2020 · Research Article · Frontiers in pharmacology

Inonotus obliquus Polysaccharide Ameliorates Azoxymethane/Dextran Sulfate Sodium-Induced Colitis-Associated Cancer in Mice via Activation of the NLRP3 Inflammasome.

Inonotus obliquus polysaccharide (IOP), the primary constituent of the parasitic fungus Inonotus obliquus, has anti-tumor, anti-inflammatory, anti-oxidation effects. However, the roles of IOP on colitis-associated cancer (CAC) are still unclear..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Chaga · 2020 · Journal Article · International journal of biological macromolecules

Inonotus obliquus polysaccharides induces apoptosis of lung cancer cells and alters energy metabolism via the LKB1/AMPK axis.

The present study explores the mechanisms underlying the anti-cancer action of Inonotus obliquus polysaccharides (IOP). Thus, we characterized the IOP components extracted from Chaga sclerotium and, found that the extracts contained 70% polysaccharides with an average molecular weight of 4.5 × 104 Da consisting of 75%….

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Oyster Mushroom · 2020 · Journal Article · Chemosphere

Investigating the potential of sunflower species, fermented palm wine and Pleurotus ostreatus for treatment of petroleum-contaminated soil.

Phyto- and myco-remediation have been identified as sustainable options for treatment of petroleum-contaminated soils. To appraise the benefits thereof, the potentials of 3 sunflower species, 2 palm wine types and P.

High relevance

Cordyceps · 2020 · Research Article · Food science of animal resources

Investigation of Taste-Related Compounds and Antioxidative Profiles of Retorted Samgyetang Made from Fresh and Dried Cordyceps militaris Mushrooms.

This study was performed to investigate the effects of taste-related compounds and antioxidatve profiles of retorted samgyetang made from fresh and dried Cordyceps militaris (C. militaris) mushrooms..

High relevance

Maitake · 2020 · Journal Article · International journal of biological macromolecules

Investigation of the uptake and transport of polysaccharide from Se-enriched Grifola frondosa in Caco-2 cells model.

A variety of beneficial pharmacological activities have been reported for Se-enriched Grifola frondosa polysaccharides. However, little has been reported on its absorption, and its intestinal uptake and transport profiles remain unknown..

Immune supportGut & microbiome

High relevance

Shiitake · 2020 · Journal Article · Carbohydrate polymers

Isolation and comparison of α- and β-D-glucans from shiitake mushrooms (Lentinula edodes) with different biological activities.

A polysaccharide-enriched extract obtained from Lentinula edodes was submitted to several purification steps to separate three different D-glucans with β-(1→6), β-(1→3),(1→6) and α-(1→3) linkages, being characterized through GC-MS, FT-IR, NMR, SEC and colorimetric/fluorimetric determinations..

OncologyImmune supportMetabolic health

High relevance

Almond Mushroom · 2020 · Journal Article · International journal of biological macromolecules

Isolation and purification of acidic polysaccharides from Agaricus blazei Murill and evaluation of their lipid-lowering mechanism.

Polysaccharides are important active constituents of Agaricus blazei Morrill. In the present study, WABM-A was isolated from WABM using DEAE-cellulose, and subsequently purified using sepharose CL-6B to obtain the acidic polysaccharide WABM-A-b..

Immune supportMetabolic healthLiver support

High relevance

Oyster Mushroom · 2020 · Research Article · Molecules (Basel, Switzerland)

Label-Free Proteomics Reveals the Molecular Mechanism of Subculture Induced Strain Degeneration and Discovery of Indicative Index for Degeneration in Pleurotus ostreatus.

Pleurotus ostreatus is one of the widely cultivated edible fungi across the world. Mycelial subculture is an indispensable part in the process of cultivation and production for all kinds of edible fungi.

High relevance

Oyster Mushroom · 2020 · Journal Article · Applied microbiology and biotechnology

Lactic acid accumulation under heat stress related to accelerated glycolysis and mitochondrial dysfunction inhibits the mycelial growth of Pleurotus ostreatus.

High temperature is a major threat to Pleurotus ostreatus cultivation. In this study, a potential mechanism by which P.

Energy & fatigueMetabolic health

High relevance

Shiitake · 2020 · Journal Article · Applied microbiology and biotechnology

Latcripin-7A, derivative of Lentinula edodes C91-3, reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G1 phase in breast cancer cells.

Due to the high mortality rate and an increase in breast cancer incidence, it has been challenging for researchers to come across an effective chemotherapeutic strategy with minimum side effects. Therefore, the need for the development of effective chemotherapeutic drugs is still on the verge..

OncologyEnergy & fatigue

High relevance

Shiitake · 2020 · Research Article · Biological trace element research

Lentinula edodes as a Source of Bioelements Released into Artificial Digestive Juices and Potential Anti-inflammatory Material.

Lentinula edodes (shiitake), an edible and medicinal mushroom, was chosen for this study with the aim of evaluating the possibility of release of bioelements into artificial digestive juices and analyzing the anti-inflammatory properties..

Immune supportEnergy & fatigueGut & microbiome

High relevance

King Oyster · 2020 · Journal Article · International journal of medicinal mushrooms

Ligno(hemi)cellulolytic Enzyme Profiles during the Developmental Cycle of the Royal Oyster Medicinal Mushroom Pleurotus eryngii (Agaricomycetes) Grown on Supplemented Agri-Wastes.

We have determined the production profiles of major ligno(hemi)cellulolytic enzymes at different stages of the mushroom development cycle during industrial scale cultivation of Pleurotus eryngii on supplemented agri-wastes..

Gut & microbiome

High relevance

Reishi · 2020 · Journal Article · International journal of medicinal mushrooms

Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes) Ameliorates Spatial Learning and Memory Deficits in Rats with Hypercholesterolemia and Alzheimer's Disease.

Hypercholesterolemia has been implicated as one of the pathomechanistic factors of Alzheimer's disease (AD), the most common neurodegenerative disorder affecting memory and learning abilities..

Cognition & nervesEnergy & fatigueMetabolic health

High relevance

Reishi · 2020 · Journal Article · International journal of medicinal mushrooms

Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Ameliorates Nonspatial Learning and Memory Deficits in Rats with Hypercholesterolemia and Alzheimer's Disease.

Alzheimer's disease (AD) is the leading neurodegenerative disorder affecting memory and learning of aged people. Hypercholesterolemia had been implicated as one of the stark hallmarks of AD.

Cognition & nervesMetabolic health

High relevance

Reishi · 2020 · Journal Article · International journal of medicinal mushrooms

Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Polysaccharides Suppressed Adipogenesis and Stimulated Lipolysis in HPA-v and 3T3-L1 Adipocytes.

Ganoderma lucidum polysaccharides (GLP) are one of the major bioactive components with many beneficial properties. In the present study we aimed to systematically evaluate the effects of GLP on lipid metabolism in human (HPA-v) and murine adipocytes (3T3-L1).

Immune supportMetabolic health

High relevance

Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms

Lipids in an Ethyl Acetate Fraction of Caterpillar Medicinal Mushroom, Cordyceps militaris (Ascomycetes), Reduce Nitric Oxide Production in BV2 Cells via NRF2 and NF-κB Pathways.

Cordyceps militaris is known for its curative properties. The present study was undertaken to evaluate the reduction of nitric oxide production by BV2 cells by the bioactive fraction of stroma powder of C.

OncologyImmune support

High relevance

Cordyceps · 2020 · Research Article · Biology

Metabolic Responses of Carotenoid and Cordycepin Biosynthetic Pathways in Cordyceps militaris under Light-Programming Exposure through Genome-Wide Transcriptional Analysis.

Cordyceps militaris is currently exploited for commercial production of specialty products as its biomass constituents are enriched in bioactive compounds, such as cordycepin. The rational process development is important for economically feasible production of high quality bioproducts..

Metabolic health

High relevance

Chaga · 2020 · Research Article · Scientific reports

Molecular insights and cell cycle assessment upon exposure to Chaga (Inonotus obliquus) mushroom polysaccharides in zebrafish (Danio rerio).

Chaga (Inonotus obliquus) mushroom is considered as one of the most powerful antioxidants across the world. Though the therapeutic effects of Chaga components are well characterized in vitro, the in vivo developmental effects are not elucidated in detail..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Oyster Mushroom · 2020 · Journal Article · International journal of medicinal mushrooms

Nematocidal Effect of Oyster Culinary-Medicinal Mushroom Pleurotus ostreatus (Agaricomycetes) against Haemonchus contortus.

The nematocidal effect of Pleurotus ostreatus (white variety of oyster mushroom) aqueous extract (AE) was evaluated against Haemonchus contortus eggs and infective larvae (L3) in vitro and in artificially infected gerbils (Meriones unguiculatus)..

High relevance

Shiitake · 2020 · Journal Article · Mycoscience

Non-destructive analysis of the moisture content in shiitake mushrooms (Lentinula edodes) using near-infrared imaging at 1450 nm

Moisture content (MC) is an important factor in the freshness of shiitake mushrooms (Lentinula edodes). In this study, we developed a simple prediction method for MC of shiitake mushrooms using near-infrared (NIR) imaging at 1450 nm, as the band at 1450 nm is strongly correlated with OH groups..

High relevance

Cordyceps · 2020 · Journal Article · Journal of Asian natural products research

Novel liquid fermentation medium of Cordyceps militaris and optimization of hydrothermal reflux extraction of cordycepin.

In this study, we developed a novel liquid fermentation medium of Cordyceps militaris using pupa powder and wheat bran as nitrogen resources instead of the traditionally used peptone. This process not only reduced the cost by approximately 50%, but increased production by over 30%..

High relevance

King Oyster · 2020 · Research Article · RSC advances

Optimization of extraction parameters of Pleurotus eryngii polysaccharides and evaluation of the hypolipidemic effect.

The hot water extraction of polysaccharides from the fruiting body of Pleurotus eryngii was studied. In this paper, according to single-factor experiments, a response surface methodology and the Box-Behnken design were applied to optimize the extraction parameters of Pleurotus eryngii polysaccharides (PEP)..

Immune supportMetabolic healthLiver support

High relevance

Wood Ear · 2020 · Journal Article · International journal of medicinal mushrooms

Optimization of Fermentation Process and Its Impact on Gene Transcription of Intracellular Polysaccharide Synthesis in the Wood Ear Medicinal Mushroom Auricularia auricula-judae (Agaricomycetes).

To improve the production of mycelial biomass and intracellular polysaccharide (IPS), the culture medium composition and culture condition were respectively optimized by response surface methodology and one-factor-at-a-time methodology..

Immune support

High relevance

Cordyceps · 2020 · Research Article · Computational and structural biotechnology journal

Optimizing cultivation of Cordyceps militaris for fast growth and cordycepin overproduction using rational design of synthetic media.

Cordyceps militaris is an entomopathogenic fungus which is often used in Asia as a traditional medicine developed from age-old wisdom. Presently, cordycepin from C.

Metabolic health

High relevance

Cordyceps · 2020 · Journal Article · Chinese journal of natural medicines

Overexpression of ribonucleotide reductase small subunit, RNRM, increases cordycepin biosynthesis in transformed Cordyceps militaris.

Cordycepin was the first adenosine analogue used as an anticancer and antiviral agent, which is extracted from Cordyceps militaris and hasn't been biosynthesized until now..

OncologyRespiratory

High relevance

Maitake · 2020 · Journal Article · Rapid communications in mass spectrometry: RCM

Peptidyl-Lys metalloendopeptidase (Lys-N) purified from dry fruit of Grifola frondosa demonstrates "mirror"digestion property with lysyl endopeptidase (Lys-C).

RATIONALE: Lys-N, also known as lysine-specific metalloendopeptidase, functions as the "sister" enzyme of lysyl endopeptidase (Lys-C) in proteomic research. Its digestion specificity at the N-terminal lysine residue makes it a very useful tool in proteomics analysis, especially in mass spectrometry (MS)-based de novo….

Gut & microbiome

High relevance

Wood Ear · 2020 · Journal Article · International journal of biological macromolecules

Phagocytosis enhancement, endotoxin tolerance, and signal mechanisms of immunologically active glucuronoxylomannan from Auricularia auricula-judae.

Glucuronoxylomannan (AAPS) from the edible wood ear mushroom Auricularia auricula-judae has been demonstrated to exhibit immunostimulatory properties through its binding to TLR4. However, the mechanisms of immune modulation by AAPS in mammalian cells remains unclear..

Immune supportEnergy & fatigue

High relevance

Turkey Tail · 2020 · Journal Article · Applied biochemistry and biotechnology

Phenolic Compound Biotransformation by Trametes versicolor ATCC 200801 and Molecular Docking Studies.

The filamentous fungus Trametes versicolor is a rich source of laccase (Tvlac). Laccases catalyze reactions that convert substituted phenol substrates into diverse derivatives through aromatic oxidation..

High relevance

Shiitake · 2020 · Journal Article · International journal of biological macromolecules

Physicochemical properties and bioactivities of Lentinula edodes polysaccharides at different development stages.

Lentinula edodes polysaccharides from at four different development stages (referred to L1, L2, L3 and L4, respectively) were extracted by hot water method, and graded ethanol precipitation to final concentration of 20%, 50% and 70%, then12 crude polysaccharide fractions (referred to L1P20, L2P20, L3P20; L4P20, L1P50,….

Immune support

High relevance

King Oyster · 2020 · Journal Article · International journal of medicinal mushrooms

Polysaccharides from Pleurotus eryngii var. elaeoselini (Agaricomycetes), a New Potential Culinary-Medicinal Oyster Mushroom from Italy.

Three water-soluble glucans (PELPS-A1, PELPS-A2, and PELPS-A3) purified from the hot water extract of the basidiomata of an edible mushroom Pleurotus eryngii var. elaeoselini by chromatography on DEAE-cellulose 32 and Sephadex G-100 column were found to consist of only D-glucose as monosaccharide constituent..

Immune supportMetabolic health

High relevance

King Oyster · 2020 · Journal Article · Journal of food science

Preparation of newly identified polysaccharide from Pleurotus eryngii and its anti-inflammation activities potential.

The anti-inflammatory effects of two newly identified Pleurotus eryngii polysaccharides (WPEP, NPEP) were determined in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages in this study..

OncologyImmune supportMetabolic health

High relevance

Snow Fungus · 2020 · Journal Article · International journal of biological macromolecules

Production, structure, and bioactivity of polysaccharide isolated from Tremella fuciformis XY.

Tremella fuciformis polysaccharide (TFP) is an important bioactive substance in Tremella, that contributes to its use as medicine and food. In this study, a novel fungus Tremella fuciformis XY was isolated and introduced to produce macromolecule polysaccharides (TFPB)..

Immune supportEnergy & fatigueMetabolic health

High relevance

King Oyster · 2020 · Journal Article · International journal of medicinal mushrooms

Protective Effects of the King Oyster Culinary-Medicinal Mushroom, Pleurotus eryngii (Agaricomycetes), Polysaccharides on β-Amyloid-Induced Neurotoxicity in PC12 Cells and Aging Rats, In Vitro and In Vivo Studies.

Pleurotus eryngii (PE) contains polysaccharides and vitamins, and has been reported to have antidepression properties. P.

OncologyImmune supportCognition & nerves

High relevance

Cordyceps · 2020 · Research Article · BMC genomics

Proteome sequencing and analysis of Ophiocordyceps sinensis at different culture periods.

BACKGROUND: Ophiocordyceps sinensis is an important traditional Chinese medicine for its comprehensive active ingredients, such as cordycepin, cordycepic acid, and Cordyceps polysaccharide. O.

Immune supportMetabolic health

High relevance

Cordyceps · 2020 · Research Article · Insects

Quorum Sensing Activity and Hyphal Growth by External Stimuli in the Entomopathogenic Fungus Ophiocordyceps sinensis.

The entomopathogenic fungus Ophiocordyceps sinensis is one of the best known and most precious medicines and health food in China. The blastospores-hyphae (dimorphism) transition of this fungus in host hemolymph is critical for the virulence and the mummification of host larvae..

High relevance

Reishi · 2020 · Research Article · Frontiers in pharmacology

Recombinant Ganoderma lucidum Immunomodulatory Protein Improves the Treatment for Chemotherapy-Induced Neutropenia.

Ganoderma lucidum, also known as LINGZHI, has a long tradition of use in folk medicine of the Far East, which is documented in the oldest Chinese pharmacopoeia, declaring it a superior medicine. LINGZHI-8 (LZ-8) is an immunoregulatory fungal protein isolated from the fruiting body of Ganoderma lucidum..

OncologyImmune supportGut & microbiome

High relevance

Maitake · 2020 · Journal Article · Glycoconjugate journal

Relationship between heat treatment on structural properties and antitumor activity of the cold-water soluble polysaccharides from Grifola frondosa.

Grifola frondosa is a basidiomycete fungus with potential biomedical applications owing to the presence of bioactive polysaccharides. The activities of polysaccharides are influenced by many factors, particularly temperature; however, the optimal temperature and conditions for preparation of polysaccharides from this….

OncologyImmune supportEnergy & fatigue

High relevance

Turkey Tail · 2020 · Journal Article · The Science of the total environment

Removal of nonylphenol polyethoxylates by adsorption on polyurethane foam and biodegradation using immobilized Trametes versicolor.

Nonylphenol polyethoxylates (NPEOs) are banned in EU due to their endocrine disrupting properties. In a proof of concept study including continuous reactor lab-scale experiments, polyurethane foam (PUF)-immobilized Trametes versicolor was used to reduce the concentration levels of these compounds in an acidic nutrient….

High relevance

Shiitake · 2020 · Research Article · Frontiers in microbiology

RNA-seq Profiling Showed Divergent Carbohydrate-Active Enzymes (CAZymes) Expression Patterns in Lentinula edodes at Brown Film Formation Stage Under Blue Light Induction.

Lentinula edodes (shiitake mushroom) is one of the most important edible mushrooms worldwide. The L.

Immune support