MycoData

This study aimed to produce and optimize a Cordyceps militaris-based oil-in-water (O/W) nanoemulsion (NE) encapsulated in sea buckthorn oil (SBT) using an ultrasonication process. Herein, a nonionic surfactant (Tween 80) and chitosan cosurfactant were used as emulsifying agents..

OncologyImmune supportSkin & hydration

High relevance

Cordyceps · 2020 · Research Article · BMC complementary medicine and therapies

Cordyceps militaris induces apoptosis in ovarian cancer cells through TNF-α/TNFR1-mediated inhibition of NF-κB phosphorylation.

BACKGROUND: Cordyceps militaris (L.) Fr. (C.

OncologyImmune support

High relevance

Cordyceps · 2020 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Cordyceps militaris Induces Immunogenic Cell Death and Enhances Antitumor Immunogenic Response in Breast Cancer.

Cordyceps militaris has been widely used as a traditional medicine in East Asia. Its effects against breast cancer have been reported previously.

OncologyImmune support

High relevance

Cordyceps · 2020 · Journal Article · International journal of biological macromolecules

Cordyceps militaris polysaccharide converts immunosuppressive macrophages into M1-like phenotype and activates T lymphocytes by inhibiting the PD-L1/PD-1 axis between TAMs and T lymphocytes.

Tumour-associated macrophages (TAMs) inhibit the killing effect of T lymphocytes on tumour cells through the immunocheckpoint programmed death ligand-1 (PD-L1)/programmed death-1 (PD-1) axis. TAMs-targeted therapy is a promising approach that could be used to reverse the immunosuppressive tumour microenvironment..

OncologyImmune support

High relevance

Oyster Mushroom · 2020 · Journal Article · International journal of biological macromolecules

Crystallographic and calorimetric analysis on Pleurotus ostreatus lectin and its sugar complexes - promiscuous binding driven by geometry.

Carbohydrate recognition is established as a property of lectins and implicated in many functions including immunity and defense against pathogens. Many lectins are characterized and proposed for various applications owing to the above said recognition..

Immune supportCognition & nerves

High relevance

King Oyster · 2020 · Journal Article · Biotechnology and applied biochemistry

Decolorization and degradation potential of enhanced lignocellulolytic enzymes production by Pleurotus eryngii using cherry waste from industry.

Lignocellulosic wastes accumulate in large quantities and thus cause environmental issues. Cherry waste (CW) of them collected from industry was used as the substrate to increase production of lignocellulolytic enzymes, laccase (Lac), manganese peroxidase (MnP), lignin peroxidase (LiP), carboxymethyl cellulase….

Energy & fatigue

High relevance

Lion's Mane · 2020 · Journal Article · International journal of biological macromolecules

Designing selenium polysaccharides-based nanoparticles to improve immune activity of Hericium erinaceus.

In previous researches, the results showed that selenium Hericium erinaceus polysaccharide and Hericium erinaceus polysaccharide-loaded poly (lactic-co-glycolic acid) nanoparticles enhanced immune responses..

Immune supportLiver support

High relevance

Cordyceps · 2020 · Research Article · ACS omega

Determination of Adenosine and Cordycepin Concentrations in Cordyceps militaris Fruiting Bodies Using Near-Infrared Spectroscopy.

Near-infrared (NIRS) spectroscopy, coupled with partial least squares regression, was used to predict adenosine and cordycepin concentrations in fruiting bodies of Cordyceps militaris..

Energy & fatigue

High relevance

Snow Fungus · 2020 · Journal Article · Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment

Dietary risk assessment of pesticide residues on Tremella fuciformis Berk (snow fungus) from Fujian Province of China.

To assess the dietary exposure risks of pesticide residues in snow fungus for the general population and young children, 91 snow fungus samples were collected from major production areas in Fujian Province, China and the presence of 44 pesticides was determined..

High relevance

Zhu Ling · 2020 · Journal Article · International journal of medicinal mushrooms

Do the Main Components of the Sclerotia of Umbrella Polypore Mushroom, Polyporus umbellatus (Agaricomycetes), Correlate with Armillaria Associates?

Polyporus umbellatus is a traditional Chinese medicinal mushroom. The growth of P.

High relevance

Reishi · 2020 · Journal Article · International journal of medicinal mushrooms

Effect of Cultured Substrates on the Chemical Composition and Biological Activities of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes).

A systematic study was carried out to compare the chemical composition and biological activities of wood-cultured and sack-cultured Ganoderma lucidum (WG and SG, respectively). The proximate composition, microelement content, and functional compounds of the two different cultivated mushrooms were investigated..

Immune supportMetabolic health

High relevance

King Oyster · 2020 · Journal Article · Pakistan journal of biological sciences: PJBS

Effect of Different Culture Media, Grain Sources and Alternate Substrates on the Mycelial Growth of Pleurotus eryngii and Pleurotus ostreatus.

BACKGROUND AND OBJECTIVE: Oyster mushroom Pleurotus is one of the most aromatic edible mushrooms. This study evaluated a few selected determinants for promoting mycelial growth and spawn production of P.

High relevance

Reishi · 2020 · Journal Article · International journal of medicinal mushrooms

Effect of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Capsules on Colistin-Induced Nephrotoxicity.

The aim of this experimental study was to investigate the protective effect of Ganoderma lucidum capsules against colistin nephrotoxicity. The study animals were separated into four groups: control, colistin (9 mg/kg), colistin-G.

High relevance

King Oyster · 2020 · Journal Article · European journal of nutrition

Effect of mushroom polysaccharides from Pleurotus eryngii on obesity and gut microbiota in mice fed a high-fat diet.

PURPOSE: Mushrooms are reported to have a variety of health-promoting activities. However, little information is available on the effects of intake of polysaccharides from Pleurotus eryngii on obesity.

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Turkey Tail · 2020 · Journal Article · Microbial pathogenesis

Effect of Pleurotus ostreatus and Trametes versicolor on triclosan biodegradation and activity of laccase and manganese peroxidase enzymes.

INTRODUCTION: Triclosan (TCS) is an extensively used antibacterial agent which has been frequently detected in different environmental compartments. Because of TCS inhibition effect on vast majority of bacterial species, it is important to explore fungal species and their involved enzymes in TCS biodegradation..

High relevance

Oyster Mushroom · 2020 · Journal Article · Journal of food processing and preservation

Effect of the addition of edible mushroom flours (Agaricus bisporus and Pleurotus ostreatus) on physicochemical and sensory properties of cold‐stored beef patties

The characteristics of beef patties with partial replacement of fat and salt by the addition of 2.5 and 5.0% edible mushroom (Agaricus bisporus and Pleurotus ostreatus) flours were studied during cold storage..

High relevance

King Oyster · 2020 · Journal Article · International journal of medicinal mushrooms

Effect of the King Oyster Culinary-Medicinal Mushroom Pleurotus eryngii (Agaricomycetes) Basidiocarps Powder to Ameliorate Memory and Learning Deficit in Ability in Aβ-Induced Alzheimer's Disease C57BL/6J Mice Model.

One of the major causes of Alzheimer's disease (AD) is oxidative stress, which accelerates β-amyloid peptide (AP) plaque and neurofibrillary tangle accumulation in the brain..

Cognition & nervesMetabolic healthLiver support

High relevance

King Oyster · 2020 · Journal Article · Journal of food processing and preservation

Effect of Thymus vulgaris post‐extraction waste and spent coffee grounds on the quality of cultivated Pleurotus eryngii

The study demonstrated that Pleurotus eryngii cultivation on substrate enriched with thymus (Thymus vulgaris) post‐extraction waste (TPEW) and spent coffee grounds (SCG) can beneficially affect yield and modify the mineral composition, profile of phenolic compounds, organic acids, and antioxidant activity..

High relevance

Almond Mushroom · 2020 · Research Article · Food science & nutrition

Effects of Agaricus blazei Murrill polysaccharides on hyperlipidemic rats by regulation of intestinal microflora.

The present research envisaged the effects of Agaricus blazei Murrill polysaccharides (ABPs) on blood lipids and its role in regulation of the intestinal microflora in hyperlipidemic rats. The acidic polysaccharide fraction of Agaricus blazei Murrill was obtained by DEAE-cellulose ion exchange column chromatography..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Chaga · 2020 · Journal Article · International journal of medicinal mushrooms

Effects of Chaga Medicinal Mushroom Inonotus obliquus (Agaricomycetes) Extracts on NOS-cGMP-PDE5 Pathway in Rat Penile Smooth Muscle Cells.

Some medicinal mushrooms have effects on sexual dysfunctions. Nitric oxide synthase (NOS)-cyclic gua-nosine monophosphate (cGMP)-phosphodiesterase 5 enzyme (PDE5) pathway is one of the pathophysiological basis of erectile dysfunction (ED)..

Immune supportEnergy & fatigue

High relevance

Chaga · 2020 · Research Article · Analytical cellular pathology (Amsterdam)

Effects of Inonotus obliquus Polysaccharides on Proliferation, Invasion, Migration, and Apoptosis of Osteosarcoma Cells.

OBJECTIVES: To observe the effect of Inonotus obliquus polysaccharide (IOP) on the proliferation, invasion, migration, and apoptosis of osteosarcoma cells and to elucidate its underlying molecular mechanism..

OncologyImmune support

High relevance

Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms

Effects of Substrates on the Production of Fruiting Bodies and the Bioactive Components by Different Cordyceps militaris Strains (Ascomycetes).

Cordyceps militaris is a type of food and medicinal species and is widely cultured in Asia. Substrate and strain are important factors for the production of fruiting bodies and bioactive components contents in fruiting bodies of C.

High relevance

Oyster Mushroom · 2020 · Research Article · Foods (Basel, Switzerland)

Effects of Various Drying Methods on Some Physico-Chemical Properties and the Antioxidant Profile and ACE Inhibition Activity of Oyster Mushrooms (Pleurotus Ostreatus).

In food biotechnology, Pleurotus ostreatus is of great interest as a source of natural antioxidants and angiotensin-converting enzyme (ACE) inhibitors. However, research in this area has not yet been completed..

Gut & microbiomeSkin & hydration

High relevance

Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms

Enhanced Cordycepin Production in Caterpillar Medicinal Mushroom, Cordyceps militaris (Ascomycetes), Mutated by a Multifunctional Plasma Mutagenesis System.

A multifunctional plasma mutation system (MPMS) method was used to create high cordycepin-yielding mutations from wild Cordyceps militaris, which yielded many viable mutants, many of which produced more cordycepin compared to the wild strain..

High relevance

Cordyceps · 2020 · Research Article · Biotechnology reports (Amsterdam, Netherlands)

Enhanced production of cordycepin in Ophiocordyceps sinensis using growth supplements under submerged conditions.

Cordycepin is a crucial bioactive compound produced by the fungus Cordyceps spp. Its therapeutic potential has been recognized for a wide range of biological properties such as anticancer, anti-diabetic, antidepressant, antioxidant, immunomodulation, etc..

OncologyImmune supportCognition & nervesEnergy & fatigue

High relevance

Cordyceps · 2020 · Research Article · Nanomaterials (Basel, Switzerland)

Enhancement of Chemical Stability and Dermal Delivery of Cordyceps militaris Extracts by Nanoemulsion.

This study aimed to develop nanoemulsions for enhancing chemical stability and dermal delivery of Cordyceps militaris extracts. C.

OncologyLiver supportSkin & hydration

High relevance

Turkey Tail · 2020 · Journal Article · Food & function

Enhancement of the anti-inflammatory properties of grape pomace treated by Trametes versicolor.

The application of solid-state fermentation for the production of value-added products from the agro- and food-industry residues has been recently investigated greatly. The white-rot basidiomycete Trametes versicolor is a widely used fungi for the degradation lignocellulosic material in solid-state conditions..

Immune supportEnergy & fatigue

High relevance

Cordyceps · 2020 · Research Article · Food science & nutrition

Enzymatic hydrolysis pretreatment for enhancing the protein solubility and physicochemical quality of Cordyceps militaris chicken soup.

Chicken soup is one of the most popular Chinese-style soups due to its high nutritional value and special flavor. However, the nutrients, mainly soluble protein, in the soup are relatively low..

High relevance

Lion's Mane · 2020 · Journal Article · Anti-cancer agents in medicinal chemistry

Erinacerins, Novel Glioma Inhibitors from Hericium erinaceus, Induce Apoptosis of U87 Cells through Bax/Capase-2 Pathway.

BACKGROUND: Glioma is the most common tumor of the central nervous system. Hericium erinaceus, which has been reported to have a variety of pharmacological activities, is a widely used Traditional Chinese Medicine (TCM), and also a kind of delicious food accepted by the public..

Oncology

High relevance

Shiitake · 2020 · Research Article · International journal of molecular sciences

Ethyl Acetate Fraction of Aqueous Extract of Lentinula edodes Inhibits Osteoclastogenesis by Suppressing NFATc1 Expression.

Bone tissue is continuously remodeled by the coordinated action of osteoclasts and osteoblasts. Nuclear factor-activated T cells c1 (NFATc1) is a well-known transcription factor for osteoclastogenesis and transcriptionally activated by the c-Fos and nuclear factor-kappa B (NF-κB) signaling pathways in response to….

High relevance

King Oyster · 2020 · Journal Article · Preparative biochemistry & biotechnology

Evaluation and characterization of Pleurotus eryngii extract-loaded chitosan nanoparticles as antimicrobial agents against some human pathogens.

With the increase of antibiotic resistance, which is present at a worrying rate, research on the use of newly developed nanoparticles as an antimicrobial agent with green biotechnology has intensified..

High relevance

Oyster Mushroom · 2020 · Research Article · AMB Express

Evaluation of waste paper for cultivation of oyster mushroom (Pleurotus ostreatus) with some added supplementary materials.

Mushroom cultivation is an economically feasible bio-technological process for conversion of various lignocellulosic wastes. The aim of this study was to evaluate the suitability of waste paper supplemented with corn stalk and wheat bran for oyster mushroom cultivation..

High relevance

Oyster Mushroom · 2020 · Research Article · Biochemistry and biophysics reports

Exopolysaccharide-peptide complex from oyster mushroom (Pleurotus ostreatus) protects against hepatotoxicity in rats.

Liver damage involves oxidative stress and a progression from chronic hepatitis to hepatocellular carcinoma (HCC). The increased incidence of liver disease in Egypt and other countries in the last decade, coupled with poor prognosis, justify the critical need to introduce alternative chemopreventive agents that may….

OncologyImmune supportLiver support

High relevance

Oyster Mushroom · 2020 · Research Article · Microorganisms

Expression of Pleurotus ostreatus Laccase Gene in Pichia pastoris and Its Degradation of Corn Stover Lignin.

Pleurotus ostreatus is a species of white-rot fungi that effectively degrades lignin. In this study, we aimed to efficiently express the lac-2 gene of Pleurotus ostreatus in the Pichia pastoris X33 yeast strain..

High relevance

Turkey Tail · 2020 · Journal Article · International journal of medicinal mushrooms

Extracellular Polysaccharopeptides from Fermented Turkey Tail Medicinal Mushroom, Trametes versicolor (Agaricomycetes), Mitigate Oxidative Stress, Hyperglycemia, and Hyperlipidemia in Rats with Type 2 Diabetes Mellitus.

The antihyperglycemic activity of extracellular polysaccharopeptides (ePSP) obtained from Trametes versicolor (TV) strain LH-1 has been reported to increase cellular glucose uptake in HepG2 cells in an insulin-independent manner..

Metabolic health

High relevance

Lion's Mane · 2020 · Journal Article · International journal of biological macromolecules

Extraction of a novel fungal chitin from Hericium erinaceus residue using multistep mild procedures.

In this study, a novel fungal chitin was extracted from Hericium erinaceus residue using moderate chemical sequential extraction procedures. The effects of deproteinization conditions, including NaOH concentration, reaction temperature, and reaction time, on the chitin yield, purity, molecular weight (Mw), and degree….

High relevance

King Oyster · 2020 · Journal Article · International journal of food science & technology

Extraction, isolation, characterisation, antioxidant and anti‐fatigue activities of Pleurotus eryngii polysaccharides

Pleurotus eryngii polysaccharide (PEP) was obtained using hot water extraction and ethanol precipitation. Three purified polysaccharide fractions (namely PEP1‐A, PEP2‐A and PEP3‐A) were obtained from PEP using DEAE‐cellulose‐52 chromatography and a gel permeation Sephadex G‐100 column..

Immune supportEnergy & fatigueMetabolic health

High relevance

Chaga · 2020 · Research Article · Nutrients

Extracts of Phellinus linteus, Bamboo (Sasa senanensis) Leaf and Chaga Mushroom (Inonotus obliquus) Exhibit Antitumor Activity through Activating Innate Immunity.

Natural products have attracted great interest for some time as alternative methods against cancers by fulfilling immunomodulating properties. In this study, we investigated the activity of hot water extracts (120 °C, >30 min) of Phellinus linteus, fresh leaves of Kumaizasa bamboo and Chaga mushroom which we called….

OncologyImmune supportGut & microbiome

High relevance

Shiitake · 2020 · Research Article · Foods (Basel, Switzerland)

Fatty Acids and Stable Isotope Ratios in Shiitake Mushrooms (Lentinula edodes) Indicate the Origin of the Cultivation Substrate Used: A Preliminary Case Study in Korea.

Shiitake mushroom (Lentinula edodes) is commonly consumed worldwide and is cultivated in many farms in Korea using Chinese substrates owing to a lack of knowledge on how to prepare sawdust-based substrate blocks (bag cultivation)..

High relevance

Shiitake · 2020 · Journal Article · Plant disease

First Report of Cobweb Disease Caused by Cladobotryum mycophilum on Cultivated Shiitake Mushroom (Lentinula edodes) in China

Lentinula edode (shiitake) is one of the highest-yielding edible fungi in China, widely appreciated for its unique rich flavor and medicinal properties (Chang and Miles 2004)..

Gut & microbiome

High relevance

Cordyceps · 2020 · Journal Article · Plant disease

First Report of White Mold Caused by Trichothecium crotocinigenum on Cordyceps militaris in China

Cordyceps militaris (L.) Fr. is a highly valued edible and medicinal fungus (Cui 2015).

Gut & microbiome

High relevance

Reishi · 2020 · Journal Article · International journal of medicinal mushrooms

Formulation and Evaluation of a Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Nutraceutical Hydroalcoholic Suspension.

Ganoderma lucidum is a mushroom used in traditional Chinese medicine for its purported health benefits. Its complex chemical composition and potential synergies between bioactive compounds make it desirable to design a product that retains most of these compounds in a single formulation..

High relevance

Lion's Mane · 2020 · Journal Article · Food & function

Fruiting body polysaccharides of Hericium erinaceus induce apoptosis in human colorectal cancer cells via ROS generation mediating caspase-9-dependent signaling pathways.

The fruiting bodies of Hericium erinaceus (Bull.) Pers. are commonly used in China in the treatment of digestive system diseases.

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Reishi · 2020 · Journal Article · Journal of ethnopharmacology

Gano oil: A novel antinociceptive agent extracted from Ganoderma lucidum inhibits paw oedema and relieves pain by hypnotic and analgesic actions of fatty acid amides.

ETHNOPHARMACOLOGICAL RELEVANCE: Lingzhi or Reishi - Ganoderma lucidum (Fr.) P. Karst is an extensively used medicinal mushroom in folklore and traditional medicine in south East Asia to treat a number of diseases.

High relevance

Reishi · 2020 · Research Article · Pharmaceuticals (Basel, Switzerland)

Ganoderma lucidum Ethanol Extracts Enhance Re-Epithelialization and Prevent Keratinocytes from Free-Radical Injury.

Ganoderma lucidum or Reishi is recognized as the most potent adaptogen present in nature, and its anti-inflammatory, antioxidant, immunomodulatory and anticancer activities are well known. Moreover, lately, there has been an increasing interest from pharmaceutical companies in antiaging G..

OncologyImmune supportSkin & hydration

High relevance

Reishi · 2020 · Research Article · Biology

Ganoderma Lucidum from Red Mushroom Attenuates Formaldehyde-Induced Liver Damage in Experimental Male Rat Model.

The majority of liver-related illnesses are caused by occupational and domestic exposure to toxic chemicals like formaldehyde (FA), which is widely common in Africa and the world at large. Hence, measures should be taken to protect humans from its hazardous effects..

Immune supportMetabolic healthLiver support

High relevance

Cordyceps · 2020 · Journal Article · International journal of biological macromolecules

Gene cloning, expression and homology modeling of first fibrinolytic enzyme from mushroom (Cordyceps militaris).

Fibrinolytic enzymes are important thrombolytic agents for blood-clotting disorders like cardiovascular diseases. Availability of novel recombinant fibrinolytic enzymes can overcome the shortcomings of current thrombolytic drugs..

High relevance

Cordyceps · 2020 · Journal Article · Journal of biotechnology

Genome mining and biosynthesis of the Acyl-CoA:cholesterol acyltransferase inhibitor beauveriolide I and III in Cordyceps militaris.

Ascomycete fungi Cordyceps are widely used in traditional Chinese medicine, and numerous investigations have been carried out to uncover their biological activities. However, primary researches on the physiological effects of Cordyceps were committed using crude extracts..

Cognition & nervesMetabolic health

High relevance

Cordyceps · 2020 · Research Article · AMB Express

Genome sequencing and analysis of fungus Hirsutella sinensis isolated from Ophiocordyceps sinensis.

Ophiocordyceps sinensis has been used as a traditional medicine or healthy food in China for thousands of years. Hirsutella sinensis was reported as the only correct anamorph of O.

Immune support

High relevance

King Oyster · 2020 · Research Article · Applied microbiology and biotechnology

High-level expression of aryl-alcohol oxidase 2 from Pleurotus eryngii in Pichia pastoris for production of fragrances and bioactive precursors.

The fungal secretome comprises various oxidative enzymes participating in the degradation of lignocellulosic biomass as a central step in carbon recycling. Among the secreted enzymes, aryl-alcohol oxidases (AAOs) are of interest for biotechnological applications including production of bio-based precursors for….

OncologyCognition & nervesMetabolic health