MycoData

Immune supportMetabolic health

Snow Fungus · 2022 · Preprint · journal metadata

Structural analysis, in vitro antioxidant and lipid-lowering activities of purified Tremella fuciformis polysaccharide fractions

Abstract In order to study the composition, structure and physicochemical properties of Tremella fuciformis polysaccharide (TFPS), four new polysaccharide fractions (TFPS1, TFPS2, TFPS3 and TFPS4) were successfully isolated from the hot-water extracted crude polysaccharides by DEAE-52 cellulose column..

Cordyceps · 2021 · Preprint · journal metadata

Building an Integrative and Testable Hypothesis on How Edaphic Factors Ultimately Influence the Occurrence and Quality of Ophiocordyceps Sinensis, the Vegetable Caterpillar

Abstract BackgroundThe yield of commercially harvested “vegetable caterpillar” Ophiocordyceps sinensis has dramatically plummeted in the last few decades, while market demand has increased..

Snow Fungus · 2021 · Preprint · journal metadata

Characterization Of a G Protein α Subunit Encoded Gene From The Dimorphic Fungus-Tremella Fuciformis

Abstract Tremella fuciformis is a dimorphic fungus which can undertake the reversible transition between yeast and pseudohypha forms. G protein α subunit (Gα) carries different signals to regulate a variety of biological processes in eukaryotes, including fungal dimorphism..

Mesima · 2021 · Preprint · journal metadata

Clinical Trial to Analyze the Effect of Oral Intake of Phellinus Linteus(Sanghuang) Extract on Immune Function: A Study Protocol for a Randomized, Double-blind Controlled Trial

Abstract Background: As Korea becomes an aging society, interest in health care has increased. In particular, there is an increasing demand for immune function improvement to prevent infectious diseases.

OncologyImmune support

Immune supportEnergy & fatigue

Shiitake · 2021 · Preprint · journal metadata

Corncob as a Substrate for the Cultivation of Lentinula Edodes

Abstract Corncob is a major agricultural waste in the world. The study aims to evaluate the effect of using corncob as a substrate for Lentinula edodes cultivation, so as to provide an economic and eco-friendly approach to transform waste biomass into high quality edible mushrooms (whose original substrate - wood - is….

Immune supportSkin & hydration

Chaga · 2021 · Published Erratum · Heliyon

Corrigendum to "Chaga mushroom (Inonotus obliquus) polysaccharides exhibit genoprotective effects in UVB-exposed embryonic zebrafish (Danio rerio) through coordinated expression of DNA repair genes" [Heliyon 7 (2) (February 2021) Article e06003].

[This corrects the article DOI: 10.1016/j.heliyon.2021.e06003.]..

Oyster Mushroom · 2021 · Preprint · journal metadata

Development of Mycelium Materials Incubating Pleurotus Ostreatus Fungi With Different Substrates Composed of Poplar Sawdust and Cottonseed Hull

The mycelium materials incubating Pleurotus ostreatus fungi based on different substrate compositions were developed, the main components of which were poplar sawdust and cottonseed hull in different proportions..

Energy & fatigue

Chaga · 2021 · Preprint · journal metadata

Effect of Alkali-Treated Birch Sawdust on the Lignocellulase Secretion and Exo-Polysaccharide Production by Inonotus Obliquus Under Submerged Fermentation and its Lignocellulose Degradation Patterns

Abstract The objectives of this study were to investigate the medicinal mushroom Inonotus obliquus on the production of polysaccharides and changes of extracellular lignocellulolytic enzymes during submerged fermentation using alkali-treated birch sawdust as substrate..

Oyster Mushroom · 2021 · Preprint · journal metadata

Effect of Nutritional Factors and Copper on the Regulation of Laccase Enzymes Production in Pleurotus ostreatus

This research aimed to establish the relationship between carbon-nitrogen nutritional factors and copper sulfate on laccase activity (LA) by Pleurotus ostreatus. Culture media composition was tested to choose the nitrogen source.

OncologyImmune supportSkin & hydration

Chaga · 2021 · Preprint · journal metadata

Genome Sequencing of Inonotus Obliquus Reveals Insights Into Candidate Genes Involved In Secondary Metabolite Biosynthesis

Background: Inonotus obliquus is an important edible and medicinal mushroom that was shown to have many pharmacological activities in preclinical trials, including anti-inflammatory, antitumor, immunomodulatory, and antioxidant effects..

Chaga · 2021 · Preprint · journal metadata

Lignin-Degrading Enzymes From a Pathogenic Canker-Rot Fungus, Inonotus Obliquus Strain IO-B2 (NBRC 113408)

Inonotus obliquus is pathogenic fungus on living trees and has been widely used as a traditional medicine for cancer therapy. Although it has been reported that lignocellulose-degrading enzymes are involved in the early stage of host infection, the parasitic life cycle of this fungus has not been fully clarified..

Oncology

Immune supportMetabolic health

Shiitake · 2021 · Preprint · journal metadata

Optimization of Culture Conditions in a Bioreactor for the Production of Biomass and Metabolites of the Macromycete Lentinula Edodes

Abstract Lentinula edodes is an edible mushroom known for its medicinal properties attributed to different secondary metabolites. In this article, the effect of glucose concentration, aeration and agitation on the production of biomass and intrametabolites in submerged fermentation was evaluated..

OncologyImmune supportGut & microbiome

Chaga · 2021 · Preprint · journal metadata

Potential Target Screening and Molecular Docking of Newly Isolated Compound From Inonotus Obliquus

Compound (1-(4-hydroxyphenyl)-3-methoxypropan-1-one) is a newly isolated compound from Inonotus obliquus. In this paper, four target protein prediction methods were used to search the potential targets of compounds.

OncologyImmune supportEnergy & fatigue

Shiitake · 2021 · Preprint · journal metadata

Selenium-Containing Exopolysaccharides Isolated from the Culture Medium of Lentinula edodes: Structure and Biological Activity

In continuation of our research on the influence of selenium incorporation on the biosynthesis, structure, immunomodulatory and antioxidant activities of polysaccharides of fungal origin, we have isolated from a post-culture medium of Lentinula edodes a selenium (Se)-containing exopolysaccharide fraction composed….

Energy & fatigueMetabolic healthGut & microbiome

Oyster Mushroom · 2021 · Preprint · journal metadata

Treatment of Rice Stubble with Pleurotus Ostreatus and Urea Improves the Growth Performance in Slow-Growing Goats

The objective of this study was to evaluate the efficacy of fungal treatment (Pleurotus ostreatus) of urea-treated rice stubble on growth performance in slow-growing goats..

King Oyster · 2020 · Journal Article · Ying yong sheng tai xue bao = The journal of applied ecology

[Effects of sawdust dosage on the diversity and community structure of bacteria associated with the hyphae of Pleurotus eryngii].

Some fungi engage symbiosis with bacteria, which can effectively promote the metabolism and growth of fungi. The diversity and community structure of bacteria can reflect the growth and substrate utilization of fungi..

Gut & microbiome

Cordyceps · 2020 · Journal Article · Journal of pharmaceutical and biomedical analysis

1H NMR spectroscopy-based metabolic profiling of Ophiocordyceps sinensis and Cordyceps militaris in water-boiled and 50% ethanol-soaked extracts.

Ophiocordyceps sinensis, a well-known Chinese complementary herb, is a rare and valuable therapeutic resource. Cordyceps militaris (C.

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Cordyceps · 2020 · Journal Article · Natural product research

1H NMR-based metabonomics of the hypoglycemic effect of polysaccharides from Cordyceps militaris on streptozotocin-induced diabetes in mice.

The crude polysaccharide was extracted from Cordyceps militaris. Material ratio of powder and water was 1:10.

Cordyceps · 2020 · Journal Article · Natural product research

A new nucleoside and two new pyrrole alkaloid derivatives from Cordyceps militaris.

A new nucleoside, a new natural product nucleoside, and two new pyrrole alkaloids derivatives with eight known compounds were isolated from the fruiting body of Cordyceps militaris..

Cordyceps · 2020 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

A novel combination of enzymatic hydrolysis and fermentation: Effects on the flavor and nutritional quality of fermented Cordyceps militaris beverage

This study evaluated the effects of enzymatic hydrolysis and fermentation on the flavor and nutritional quality of fermented Cordyceps militaris beverage. Enzymatic hydrolysis can produce more reducing sugars and provide an appropriate fermentation substrate for the growth of bacteria..

Cognition & nervesGut & microbiome

Enoki · 2020 · Research Article · Frontiers in microbiology

A WD40 Protein Encoding Gene Fvcpc2 Positively Regulates Mushroom Development and Yield in Flammulina velutipes.

Ascomycota and Basidiomycota are two closely related phyla and fungi in two phyla share some common morphological developmental process during fruiting body formation. In Neurospora crassa, the Gβ-like protein CPC-2 with a seven-WD40 repeat domain was previously reported..

OncologyImmune supportLiver support

Maitake · 2020 · Journal Article · International journal of biological macromolecules

A β-glucan from Grifola frondosa effectively delivers therapeutic oligonucleotide into cells via dectin-1 receptor and attenuates TNFα gene expression.

Grifola frondosa is an edible and medicinal mushroom with great nutritional values and bioactivities. In the present study, a soluble homogeneous β-glucan, GFPS, with high molecular mass of 5.42 × 106 Da was purified from the fruit bodies of Grifola frondosa using 5% cold NaOH..

Almond Mushroom · 2020 · Research Article · Oncology letters

Agaricus blazei extract (FA-2-b-β) induces apoptosis in chronic myeloid leukemia cells.

Agaricus blazei Murill (AbM) is a mushroom belonging to the Basidiomycetes family, which is believed to have antitumor and antioxidative activities. Proteoglycans and ergosterol are considered the key compounds of AbM for antitumor properties and so are used in complementary and alternative medicine as an anticancer….

Oncology

Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms

An Efficient Strategy for Enhancement of Bioactive Compounds in the Fruit Body of Caterpillar Medicinal Mushroom, Cordyceps militaris (Ascomycetes), by Spraying Biotic Elicitors.

Cordyceps militaris is a mushroom species with high nutritive and medicinal values based on diverse bioactive metabolites. The contents of bioactive ingredients are indicative of the quality of commercially available fruit body of this fungus..

Immune supportSkin & hydration

Cordyceps · 2020 · Research Article · Physical activity and nutrition

Anti-atopic dermatitis properties of Cordyceps militaris on TNFα/IFNγ-stimulated HaCaT cells and experimentally induced atopic dermatitis in mice.

PURPOSE: This study evaluated the anti-atopic dermatitis (AD) properties of Cordyceps militaris (CM) aqueous extract in keratinocytes in vitro and in vivo. We investigated the nutraceutical composition of the CM extract, including its protein, carbohydrate, and selected phytochemical content..

Oyster Mushroom · 2020 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Anti-Inflammatory Activity of Pleurotus ostreatus, a Culinary Medicinal Mushroom, in Wistar Rats.

UNLABELLED: Context. Pleurotus ostreatus (P.o) is a culinary mushroom which is commonly called as "oyster mushroom" belonging to the Basidiomycetous fungi of the order Agaricales and family Pleurotaceae..

Enoki · 2020 · Journal Article · International journal of medicinal mushrooms

Antibacterial Activity of Fruiting Body Extracts from Culinary-Medicinal Winter Mushroom, Flammulina velutipes (Agaricomycetes) against Oral Pathogen Streptococcus mutans.

The edible medicinal mushroom Flammulina velutipes (enokitake) has many applications as food and medicine, but its application in dentistry is unknown. This study aims to investigate the inhibitory effect of fruiting body extracts from F..

Oncology

OncologyImmune supportSkin & hydration

Cordyceps · 2020 · Research Article · Mycobiology

Antithrombotic and Antiplatelet Effects of Cordyceps militaris.

Cordyceps is a genus of ascomycete fungi and is well known as one of the important medical fungi in Chinese, Korea, and other Asian countries, because of its various beneficial effects on human health..

Enoki · 2020 · Research Article · Foods (Basel, Switzerland)

Application of Enoki Mushroom (Flammulina Velutipes) Stem Wastes as Functional Ingredients in Goat Meat Nuggets.

The impact of different amounts (2%, 4% and 6%) of enoki (Flammulina velutipes) mushroom stem waste (MSW) powder on the physicochemical quality, color and textural, oxidative stability, sensory attributes and shelf-life of goat meat nuggets was evaluated..

Almond Mushroom · 2020 · Research Article · Food science & nutrition

Assessment of antioxidant and antidiabetic properties of Agaricus blazei Murill extracts.

Agaricus blazei Murill (ABM), a medicinal mushroom, has beneficial effects on various human metabolic diseases. The objective of this research was to evaluate the antioxidant and antidiabetic properties of ABM extracts (ethanol extract and ethyl acetate extract)..

Turkey Tail · 2020 · Journal Article · International journal of medicinal mushrooms

Assessment of Bioactive Compounds and Antioxidant Activity of Turkey Tail Medicinal Mushroom Trametes versicolor (Agaricomycetes).

Trametes versicolor is important for its medicinal rather than nutritional value. It has a variety of pharmacological activities.

OncologyImmune supportEnergy & fatigueRespiratory

Cordyceps · 2020 · Research Article · Mycobiology

Beneficial Effect of Cordyceps militaris on Exercise Performance via Promoting Cellular Energy Production.

Cordyceps militaris has been reported to the diverse pharmaceutical effects including cancer, inflammatory diseases, and bacteria or virus infection. However, the effect of C.

Immune supportEnergy & fatigueMetabolic healthLiver support

Reishi · 2020 · Journal Article · International journal of medicinal mushrooms

Bioactivities and Molecular Characterizations of the Polysaccharide(s) from Ultrasonic-Circulating Extracts of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes).

Total polysaccharide (i.e., GLP-UCE) was effectively isolated from the crude polysaccharide extract powder of Ganoderma lucidum by ultrasonic-circulating extraction, which was separated into three fractions (i.e., GLP-U40, GLP-U60, and GLP-U80) by ethanol fractional precipitation..

Immune supportEnergy & fatigue

Cordyceps · 2020 · Journal Article · Natural product research

Carboxymethylation and acetylation of the polysaccharide from Cordyceps militaris and their α-glucosidase inhibitory activities.

The crude polysaccharide extracted from Cordyceps militaris was chemically modified to obtain carboxymethylated derivatives (CM-CPS) and acetylated derivatives (AC-CPS)..

OncologyImmune supportCognition & nervesEnergy & fatigue

Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms

Caterpillar Medicinal Mushroom, Cordyceps militaris (Ascomycetes), Mycelia Attenuates Doxorubicin-Induced Oxidative Stress and Upregulates Krebs Cycle Dehydrogenases Activity and ATP Level in Rat Brain.

Post-chemotherapy-induced cognitive dysfunction remains one of the challenges in cancer survivors. Cytokine-induced neurotoxicity manifests in subjects at any time after doxorubicin (DOX) chemotherapy..

Cognition & nervesEnergy & fatigue

Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms

Caterpillar Medicinal Mushroom, Cordyceps militaris (Ascomycetes), Protects Aβ1-42-Induced Neurologic Damage in C6 Glial Cells.

Alzheimer's disease (AD) shows neurological symptoms common to cognitive disorders and memory loss. Several hypotheses have suggested that the accumulation of amyloid-beta peptide (Aβ) and reduction of acetylcholine synthesis cause AD..

Shiitake · 2020 · Journal Article · Journal of agricultural and food chemistry

Changes in the Key Aroma Compounds of Raw Shiitake Mushrooms (Lentinula edodes) Induced by Pan-Frying As Well As by Rehydration of Dry Mushrooms.

Application of the aroma extract dilution analysis (AEDA) on an extract/distillate from raw shiitake mushrooms revealed 32 odorants among which 3-(methylthio)propanal (cooked potato), 1-octen-3-one, and 1-octen-3-ol (both mushroom-like) showed the highest flavor dilution (FD) factors..

Skin & hydration

Cordyceps · 2020 · Research Article · BMC genomics

Changes in transcriptomic and metabolomic profiles of morphotypes of Ophiocordyceps sinensis within the hemocoel of its host larvae, Thitarodes xiaojinensis.

BACKGROUND: Ophiocordyceps sinensis (Berk.) is a well-known entomopathogenic and medicinal fungus. It parasitizes and mummifies the underground ghost moth larvae to produce a fruiting body named Chinese cordyceps.

Shiitake · 2020 · Journal Article · International journal of food science & technology

Characterisation of moisture migration of shiitake mushroom (Lentinula edodes) during storage and its relationship to quality deterioration

Water is a critical factor influencing the quality of mushrooms. This paper investigated the moisture migration of shiitake mushroom during storage using low‐field nuclear magnetic resonance (LF‐NMR) and magnetic resonance imaging (MRI) and its relationship to quality deterioration..

Oyster Mushroom · 2020 · Journal Article · Journal of food science

Characterization of astragaloside I-IV based on the separation of HPTLC from Pleurotus ostreatus cultivated with Astragalus.

In this study, total saponins were extracted from Pleurotus ostreatus cultivated with Astragalus as one of organic culture substrates. High Performance Thin Layer Chromatography (HPTLC) assay showed total saponins could be separated effectively, and four kinds of spots were identified as AG I, AG II, AG III, and AG….

Energy & fatigue

King Oyster · 2020 · Journal Article · Journal of agricultural and food chemistry

Characterization of the Immunomodulatory Mechanism of a Pleurotus eryngii Protein by Isobaric Tags for Relative and Absolute Quantitation Proteomics.

PEP 1b is a novel immunoregulatory protein isolated from Pleurotus eryngii, a popular edible mushroom. In this study, isobaric tags for relative and absolute quantitation (iTRAQ) approach and bioinformatics analysis were used to characterize the PEP-1b-induced proteome alterations in Raw 264.7 macrophage cells, to….

Cognition & nervesMetabolic healthGut & microbiome

Lion's Mane · 2020 · Journal Article · Journal of ethnopharmacology

Characterization of α-glucosidase inhibitory constituents of the fruiting body of lion's mane mushroom (Hericium erinaceus).

ETHNOPHARMACOLOGICAL RELEVANCE: Hericium erinaceus, commonly called lion's mane mushroom, is an edible and medicinal mushroom that has been traditionally used for the treatment of metabolic disorders, gastrointestinal diseases and memory impairment..

King Oyster · 2020 · Research Article · BioMed research international

Chemical Composition of an Anthelmintic Fraction of Pleurotus eryngii against Eggs and Infective Larvae (L3) of Haemonchus contortus.

This study was aimed at evaluating the in vitro effect of the edible mushroom (EM) Pleurotus eryngii against the eggs and larvae (L3) of Haemonchus contortus. The evaluation included acetone (AE) and hydroalcoholic (HA) extracts of the following strains: ECS-1138, ECS-1156, ECS-1255, ECS-1258, ECS-1261, ECS-1282, and….

Cordyceps · 2020 · Journal Article · International journal of biological macromolecules

Chemical structure and inhibition on α-glucosidase of the polysaccharides from Cordyceps militaris with different developmental stages.

The natural form of wild edible fungus is the fruiting body. The cultivation of fruiting bodies from sexual reproduction requires strict conditions and long periods.

Immune supportMetabolic health

Cordyceps · 2020 · Journal Article · International journal of biological macromolecules

Chemical structure and mechanism of polysaccharide on Pb2+ tolerance of Cordyceps militaris after Pb2+ domestication.

In this study, the purified polysaccharide (DCP-I) was extracted from Cordyceps militaris domesticated with Pb2+. After that, the structural feature and mechanism of lead resistance of DCP-I were investigated using novel approaches..

Snow Fungus · 2020 · Journal Article · Journal of food quality

Co-Supplementation of Flos Sophorae Extract with Tremella fuciformis Polysaccharides Improves Physicochemical, Textural, Rheological, and Antioxidant Properties of Low-Fat Yogurts

Flos Sophorae extract (FSE) with abundant rutin and Tremella fuciformis polysaccharides (TP) could act as novel natural improvers of low-fat yogurt due to their health benefits and properties of interacting with proteins..

King Oyster · 2020 · Journal Article · Biological control

Combining the biocontrol yeast Pichia kluyveri with UV-C treatment to control postharvest decay of king oyster mushrooms (Pleurotus eryngii) caused by Lactococcus lactis subsp. lactis

Postharvest decay and senescence results in significant losses in harvested mushrooms. Integrated management, utilizing different eco-friendly, non-chemical methods, represents a strategy for controlling postharvest decay and reducing economic losses in horticultural crops that is being actively developed and….

Immune supportEnergy & fatigue

Cordyceps · 2020 · Journal Article · Microbial pathogenesis

Comparative analysis of the immune response of the wax moth Galleria mellonella after infection with the fungi Cordyceps militaris and Metarhizium robertsii.

Entomopathogenic fungi form different strategies of interaction with their insect hosts. The influence of fungal infection on insect physiology has mainly been studied for generalists (Metarhizium, Beauveria), but studies of specialized teleomorphic species, such as Cordyceps militaris, are rare..