MycoData

Immune supportMetabolic health

Reishi · 2025 · Research Article · Food science & nutrition

Ganoderic Acid A Prevented Osteoporosis by Modulating the PIK3CA/p-Akt/TWIST1 Signaling Pathway.

Osteoporosis is a disorder of decreased bone mass, microarchitectural deterioration, and fragility fractures. Ganoderma lucidum has been reported to have a variety of pharmacological activities, including immune regulation, anti-inflammation, antioxidation, sedative hypnosis, blood sugar and lipid regulation, and so….

Immune supportCognition & nervesLiver supportSkin & hydration

Lion's Mane · 2025 · Research Article · International journal of molecular sciences

Investigating the Neuroprotective, Hepatoprotective, and Antimicrobial Effects of Mushroom Extracts.

Mushrooms, renowned for their nutritional value and bioactive compounds, offer potential health benefits, including antioxidants and anti-aging properties. Aging, characterized by cellular and tissue decline, is often associated with autophagy dysfunction, a crucial cellular cleaning process..

Immune supportEnergy & fatigueRespiratory

Reishi · 2025 · Research Article · Food science & nutrition

Network Pharmacology and Experimental Validation Reveal Ganodermanontriol Modulates Pneumonia via TNF/NF-κB/MAPKs Signaling Pathway.

Ganoderma lucidum (Leyss. ex Fr.) Karst, commonly known as Lingzhi, has long been employed in traditional Chinese medicine for its medicinal properties, particularly in alleviating respiratory issues like cough and asthma..

OncologyImmune supportSkin & hydration

Shiitake · 2025 · Research Article · RSC advances

Synthesis of fungal polysaccharide-based nanoemulsions for cancer treatment.

Long valued for their therapeutic qualities, shiitake mushrooms (Lentinula edodes) are a staple of traditional Asian medicine and cuisine. They are high in bio-actives such as polysaccharides, proteins, lipids, vitamins, minerals, sterols, and phenolic compounds, which exhibit immunomodulatory, anticancer,….

Reishi · 2024 · Research Article · Foods (Basel, Switzerland)

Mechanistic and Functional Studies on the Microbial Induction of Wolfiporia cocos Liquid Fermentation Products.

Liquid fermentation is an efficient culture for obtaining polysaccharides from edible mushrooms. In this study, the polysaccharide content and biomass were examined by introducing microorganisms into the Wolfiporia cocos fermentation system..

OncologyImmune supportMetabolic healthRespiratory

Cordyceps · 2023 · Review · International journal of molecular sciences

Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer.

Edible/medicinal mushrooms have been traditionally used in Asian countries either in the cuisine or as dietary supplements and nutraceuticals. In recent decades, they have aroused increasing attention in Europe as well, due to their health and nutritional benefits..

OncologyImmune supportCognition & nervesMetabolic health

Almond Mushroom · 2022 · Randomized Controlled Trial · Cytotherapy

Prevention of chronic diabetic complications in type 1 diabetes by co-transplantation of umbilical cord mesenchymal stromal cells and autologous bone marrow: a pilot randomized controlled open-label clinical study with 8-year follow-up.

BACKGROUND AIMS: To explore the long-term safety and benefit of umbilical cord mesenchymal stromal cell (MSCs) plus autologous bone marrow mononuclear cell (aBM-MNC) stem cell transplantation (SCT) without immunotherapy in established type 1 diabetes (T1D)..

Turkey Tail · 2021 · Review · Materials (Basel, Switzerland)

Bioactives from Mushroom: Health Attributes and Food Industry Applications.

It is well-known that the utilization of mushrooms as therapeutic agents is not new. Over the past years, they have been used by local individuals as food, as well as medicines, throughout the world.

Immune supportRespiratory

Almond Mushroom · 2021 · Review · Scandinavian journal of immunology

Can medicinal mushrooms have prophylactic or therapeutic effect against COVID-19 and its pneumonic superinfection and complicating inflammation?

Medicinal mushrooms have documented effects against different diseases, including infections and inflammatory disorders. The related Basidiomycota Agaricus blazei Murill (AbM), Hericium erinaceus (HE), and Grifola frondosa (GF) have been shown to exert antimicrobial activity against viral agents, Gram-positive and….

OncologyImmune supportMetabolic health

Almond Mushroom · 2021 · Review · International journal of biological macromolecules

Polysaccharides and extracts from Agaricus brasiliensis Murill - A comprehensive review.

Edible mushrooms have been increasingly introduced into the human diet, which has driven research into their functional properties. Thus, Agaricus brasiliensis Murill or Agaricus blazei Murill (ABM) is a species native to the Brazilian biome, whose fruiting body has been used not only for dietary purposes, but also in….

Turkey Tail · 2012 · Meta-Analysis · Recent patents on inflammation & allergy drug discovery

Efficacy of Yun Zhi (Coriolus versicolor) on survival in cancer patients: systematic review and meta-analysis.

AIM: Patients with cancer frequently use herbs along with the conventional medical treatment, hoping to enhance recovery. Mushrooms have an established history of use in traditional oriental therapies.

Immune supportCognition & nervesRespiratory

Almond Mushroom · 2024 · Systematic Review · Neurocritical care

Detection and Management of Elevated Intracranial Pressure in the Treatment of Acute Community-Acquired Bacterial Meningitis: A Systematic Review.

Acute bacterial meningitis (ABM) is associated with severe morbidity and mortality. The most prevalent pathogens in community-acquired ABM are Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae..

OncologyImmune supportCognition & nervesEnergy & fatigue

Cordyceps · 2020 · Review Article · Frontiers in pharmacology

Cordyceps spp.: A Review on Its Immune-Stimulatory and Other Biological Potentials.

In recent decades, interest in the Cordyceps genus has amplified due to its immunostimulatory potential. Cordyceps species, its extracts, and bioactive constituents have been related with cytokine production such as interleukin (IL)-1β, IL-2, IL-6, IL-8, IL-10, IL-12, and tumor necrosis factor (TNF)-α, phagocytosis….

Shiitake · 2019 · Review · International journal of medicinal mushrooms

Review of Bioactive Molecules Production, Biomass, and Basidiomata of Shiitake Culinary-Medicinal Mushrooms, Lentinus edodes (Agaricomycetes).

Lentinus edodes (shiitake) is a basidiomycete that has been consumed for more than 2000 years because of its nutritional value and health benefits. It has a low lipid content, high fiber content, and a considerable amount of proteins; it also contains B vitamins and minerals in addition to a wide range of functional….

Immune supportMetabolic health

Nameko · 2017 · Review · Carbohydrate polymers

Structural characterization and rheological properties of a gel-like β-d-glucan from Pholiota nameko.

A crude fraction (SCW) was extracted with cold water from Pholiota nameko and showed mannose (24.1%), galactose (44.9%) and glucose (31%). Purification procedures resulted in a polysaccharide fraction (bG-PN), that showed only glucose..

Immune supportSkin & hydration

Shiitake · 2016 · Review · American journal of clinical dermatology

Shiitake Mushroom Dermatitis: A Review.

Shiitake mushroom dermatitis is a cutaneous reaction caused by the consumption of raw or undercooked shiitake mushrooms. Symptoms include linear erythematous eruptions with papules, papulovesicles or plaques, and severe pruritus.

Enoki · 2005 · Research Article · Ying yong yu huan jing sheng wu xue bao = Chinese journal of applied and environmental biology

Change in protein content of Flammulina velutipes and biological activities of one protein

Metadata-grounded summary: This research article indexes research on Flammulina velutipes in Ying yong yu huan jing sheng wu xue bao = Chinese journal of applied and environmental biology in 2005. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Maitake · 2005 · Research Article · Journal of integrative plant biology

Genetic transformation of tobacco with the trehalose synthase gene from Grifola frondosa Fr. enhances the resistance to drought and salt in tobacco

Metadata-grounded summary: This research article indexes research on Grifola frondosa in Journal of integrative plant biology in 2005. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Mesima · 2005 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Inhibition of IgE-dependent mouse triphasic cutaneous reaction by a boiling water fraction separated from mycelium of Phellinus linteus.

Phellinus linteus, a mushroom, contains constituents that exhibit potent antitumor effects through activating immune cells. Recently, anti-inflammatory and anti-allergic properties of P.

Maitake · 2005 · Research Article · Mycosystema

Physical and chemical properties and chemical structure of polysaccharide fraction PGF-2 from Grifola frondosa

Metadata-grounded summary: This research article indexes research on Grifola frondosa in Mycosystema in 2005. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

OncologyImmune supportMetabolic healthSkin & hydration

Maitake · 2005 · Journal Article · FEMS microbiology letters

Production of exopolysaccharide from mycelial culture of Grifola frondosa and its inhibitory effect on matrix metalloproteinase-1 expression in UV-irradiated human dermal fibroblasts.

Exopolysaccharide (EPS) was prepared by submerged mycelial culture of a newly isolated mushroom Grifola frondosa HB0071 in a 5-l stirred-tank fermenter. This fungus produced a high concentration of biomass (24.8 gl(-1) at day 4), thereby achieving high EPS concentration (7.2 gl(-1) at day 4)..

Enoki · 2005 · Research Article · Zhongguo nong xue tong bao = Chinese agricultural science bulletin

Study on the degradation of rice straw by Flammulina velutipes

Metadata-grounded summary: This research article indexes research on Flammulina velutipes in Zhongguo nong xue tong bao = Chinese agricultural science bulletin in 2005. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Maitake · 2005 · Research Article · Hubei Agricultural Sciences

Study on the optimal conditions of liquid fermentation of Grifola frondosa

Metadata-grounded summary: This research article indexes research on Grifola frondosa in Hubei Agricultural Sciences in 2005. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Maitake · 2004 · Research Article · Shi yong jun xue bao (Online)

A Preliminary study on the immunocompetence of different kinds of Grifola frondosa polysaccharide

Metadata-grounded summary: This research article indexes research on Grifola frondosa in Shi yong jun xue bao (Online) in 2004. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune supportEnergy & fatigue

Maitake · 2004 · Research Article · Shi yong jun xue bao (Online)

A study on the immunoregulatory function of Grifola frondosa polysaccharide capsule

The effects of adaptation to cold, hypoxia, or exercise on hyperbaric decompression tolerance were investigated in two factorial experiments. For either 14 or 28 days, groups of mice were handled (control); exposed discontinuously for 4 h to cold (4 degrees C) or hypoxia (P approximately 379 or 320 Torr); or exercised….

Maitake · 2004 · Research Article · Journal of China University of Medical Sciences

Effects of Grifola frondosa DNA on non--specific immunity of mice

Metadata-grounded summary: This research article indexes research on Grifola frondosa in Journal of China University of Medical Sciences in 2004. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Mesima · 2004 · Journal Article · Bioscience, biotechnology, and biochemistry

Fractionation and Anti-tumor Activity of the Mycelia of Liquid-cultured Phellinus linteus

All the fractions of Phellinus linteus mycelia showed anti-tumor activity toward solid tumors planted in mice. The highest anti-tumor activity of 81.2% was observed in the protein-glucan complex obtained by precipitating the 24% NaOH extract at pH 6.0..

Enoki · 2004 · Research Article · Mycosystema

Fruit-body color inheriance of Flammulina velutipes

Metadata-grounded summary: This research article indexes research on Flammulina velutipes in Mycosystema in 2004. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune supportMetabolic health

Lion's Mane · 2004 · Journal Article · Carbohydrate research

Structural investigation of a novel rhamnoglucogalactan isolated from the fruiting bodies of the fungus Hericium erinaceus.

A new heteropolysaccharide (HEP-1) was isolated from the fruiting bodies of Hericium erinaceus. It was estimated to have a molecular weight of 1.8x10(4) da and showed [alpha](D)(20) +129 (c 0.295, H(2)O).

Enoki · 2004 · Research Article · Journal of Henan Normal University (Natural Science)

Study on the enzyme activities and the ability of Flammulina velutipes to degrading lignin

Metadata-grounded summary: This research article indexes research on Flammulina velutipes in Journal of Henan Normal University (Natural Science) in 2004. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Lion's Mane · 2003 · Research Article · Hubei Agricultural Sciences

A study on submerged fermentation techniques of Hericium erinaceus

The serum immunoglobulin levels of lambs were monitored 24 h post partum using the zinc sulphate turbidity test. There was a wide distribution in the level of circulating maternal immunoglobulin and quite a large proportion of lambs were hypogammaglobulinaemic..

Maitake · 2003 · Research Article · Anhui nongxueyuan xuebao = Journal of Anhui Agricultural College

Anti-radiation effect of Grifola frondosa polysaccharide

Metadata-grounded summary: This research article indexes research on Grifola frondosa in Anhui nongxueyuan xuebao = Journal of Anhui Agricultural College in 2003. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Enoki · 2003 · Research Article · Jun wu xi tong = Mycosystema

Construction of cDNA expression library of Flammulina velutipes

Metadata-grounded summary: This research article indexes research on Flammulina velutipes in Jun wu xi tong = Mycosystema in 2003. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Enoki · 2003 · Journal Article · Acta crystallographica. Section D, Biological crystallography

Crystallization and preliminary X-ray crystallographic studies on the fungal immunomodulatory protein Fve from the golden needle mushroom (Flammulina velutipes).

The fungal immunomodulatory protein from the edible golden needle mushroom (Flammulina velutipes), designated Fve, is a single polypeptide consisting of 114 amino-acid residues. It is believed to trigger the mitogenic proliferation of T lymphocytes and Th1 cytokine production..

Maitake · 2003 · Research Article · Journal of Northwest Sci-Tech University of Agriculture and Forestry(Natural Science Edition)

Studies on physical and chemical characters and biological activities of polysaccharide G.F.-1 from Grifola frondosa Mycelia

Metadata-grounded summary: This research article indexes research on Grifola frondosa in Journal of Northwest Sci-Tech University of Agriculture and Forestry(Natural Science Edition) in 2003. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Maitake · 2003 · Research Article · Jun wu xi tong = Mycosystema

Studies on physicochemical characters and biological activities of polysaccharide G.F.-2 frorm grifola frondosa mycelia

Metadata-grounded summary: This research article indexes research on Grifola frondosa in Jun wu xi tong = Mycosystema in 2003. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Yellow Morel · 2002 · Journal Article · Journal of Northeast Forestry University

Biological Character of Morchella esculenta

Tetanus immunity has been studied in a population of mechanics working at the car-factory "Renault". For the study, 283 individuals were divided into 3 groups.

Enoki · 2002 · Journal Article · Wei sheng wu xue za zhi

Culture technology of Flammulina velutipes FV908 in liquid medium

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Wei sheng wu xue za zhi in 2002. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

OncologyImmune supportCognition & nervesMetabolic health

Lion's Mane · 2002 · Research Article · Cytotechnology

Effect of an exo-polysaccharide from the culture broth of Hericium erinaceus on enhancement of growth and differentiation of rat adrenal nerve cells.

It was found that an exo-biopolymer (M.W. 1,000,000, molar ratio of 1.5:1.7:1.2:0.6:0.9, glucose:galactose:xylose:mannose:fructose, purity 99%) purified from the liquid culture broth of Hericium erinaceus mycelium enhanced the growth of rat adrenal nerve cells..

Maitake · 2002 · Journal Article · Hua zhong nong ye da xue xue bao = Journal Huazhong (Central China) Agricultural University

Effect of polysaccharide of Grifola frondosa (PGF-1) on immunological function in tumor-bearing mice

The presence and growth of Aspergillus fumigatus and Aspergillus niger in the soil of ornamental plants have been demonstrated. The ecological conditions in the soil of such plants as influenced by temperature, humidity, desiccation, fertilization and ventilation obviously influence such fungal growth..

Maitake · 2002 · Journal Article · Journal of Biomathematics

Growth Dynamics and Computer Simulation in Submerged Culture for Grifola frondosa

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Journal of Biomathematics in 2002. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Enoki · 2002 · Journal Article · Acta Laser Biology Sinica

Induced mutations of variety of high yield of Flammulina velutipes SOD by He-Ne laser

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Acta Laser Biology Sinica in 2002. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Wood Ear · 2002 · Journal Article · Chinese Journal of Hospital Pharmacy

Isolation purification and molecular weight determination of acid polysaccharide of Auricularia auricula-judae (FⅡ)

Metadata-grounded summary: This journal article indexes research on Auricularia auricula-judae in Chinese Journal of Hospital Pharmacy in 2002. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Maitake · 2002 · Journal Article · Hua zhong nong ye da xue xue bao = Journal Huazhong (Central China) Agricultural University

Isolation, Purification and Characterization of Polysaccharides from Grifola frondosa

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Hua zhong nong ye da xue xue bao = Journal Huazhong (Central China) Agricultural University in 2002. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Maitake · 2002 · Journal Article · Shengwu jishu = Biotechnology

Optimization of submerged culture recipe of Grifola frondosa by uniform design

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Shengwu jishu = Biotechnology in 2002. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune supportCognition & nervesSkin & hydration

Zhu Ling · 2002 · Journal Article · Journal of Beihua University(Natural Science)

Resources and Ecological Conditions of Wild Polyporus Umbellatus in the Huangnihe Forest

The enhancement by exogenous ferric iron, both systemic and local, of the infectivity of 120 strains of bacteria, representing 17 genera, was measured in the skin of guinea-pigs. Systemic iron enhanced only 23% of 115 strains, and local iron 49% of 71 strains..

Maitake · 2002 · Journal Article · Acta Universitatis Agriculturalis Boreali-occidentalis

Study on the conditions of submerged culture of Grifola frondosa

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Acta Universitatis Agriculturalis Boreali-occidentalis in 2002. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Enoki · 2001 · Journal Article · Acta Agriculturae Universitatis Jiangxiensis

Application of rare earth element micronutrient fertilizer to Flammulina velutipes (Fr.) Sing

Metadata-grounded summary: This journal article indexes research on Flammulina velutipes in Acta Agriculturae Universitatis Jiangxiensis in 2001. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Maitake · 2001 · Journal Article · Wei sheng wu xue za zhi

Changes in several extracellular enzyme activity of Grifola frondosa during its growth and development

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Wei sheng wu xue za zhi in 2001. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..