MycoData

Lion's Mane · 2024 · Review · Neuroscience and biobehavioral reviews

A review of the effects of mushrooms on mood and neurocognitive health across the lifespan.

Mushrooms contain bioactive compounds with documented antioxidant and anti-inflammatory actions. Here, we present a systematic evaluation of epidemiological and clinical studies that investigate the role of mushrooms, either as a separate or integral dietary component, on neurocognition and mood..

Immune supportEnergy & fatigueGut & microbiomeSkin & hydration

Reishi · 2024 · Preprint · journal metadata

Protective effect and efficacy evaluation of lychee seed fermentation broth on oxidative damage of cells

Abstract Background Lychee seeds were fermented by three kinds of bacteria ( Lactobacillus plantarum, Saccharomyces cerevillus and ganoderma lucidum mycelium ), and two effective strains were selected by two indexes of activity content and antioxidant, so as to further verify whether lychee seeds have waste….

Cordyceps · 2024 · Review · Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas

The role and mechanisms of cordycepin in inhibiting cancer cells.

With the escalating incidence and mortality rates of cancer, there is an ever-growing emphasis on the research of anticancer drugs. Cordycepin, the primary nucleoside antibiotic isolated from Cordyceps militaris, has emerged as a remarkable agent for cancer prevention and treatment..

OncologyImmune supportMetabolic healthLiver support

Reishi · 2023 · Abstract · Journal of animal science

202 Functional Properties of Ganoderma Lucidum (GL) Supplementation in Canine Nutrition

Metadata-grounded summary: This abstract indexes research on Ganoderma lucidum in Journal of animal science in 2023. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

Immune supportMetabolic healthGut & microbiome

Snow Fungus · 2023 · Journal Article · Food chemistry

Acidic polysaccharides from black ear and silver ear mushrooms modulated the release and transport of glucose from gelatinised sorghum starch during digestion.

This study investigated the ability of acidic polysaccharides from Auricularia auricula-judae (AAP) and Tremella fuciformis (TFP) mushrooms to modulate starch digestion and absorption..

OncologyImmune supportLiver support

Oyster Mushroom · 2023 · Published Erratum · AMB Express

Correction: Anti-tumor effect of polysaccharide from Pleurotus ostreatus on H22 mouse Hepatoma ascites in-vivo and hepatocellular carcinoma in-vitro model.

Metadata-grounded summary: This published erratum indexes research on Pleurotus ostreatus in AMB Express in 2023. MycoData maps the paper to oncology, immune support, liver support based on its title, species context, article metadata, and study classification..

Niu-Chang-Chih · 2023 · Published Erratum · Molecules (Basel, Switzerland)

Correction: Sun et al. Ergosterol Isolated from Antrodia camphorata Suppresses LPS-Induced Neuroinflammatory Responses in Microglia Cells and ICR Mice. Molecules 2023, 28, 2406.

The original version of this article unfortunately contains an error in Figures 4B,C,H-J and 5C,D [...]..

Immune supportMetabolic healthGut & microbiome

Shiitake · 2023 · Journal Article · Food research international (Ottawa, Ont.)

Shiitake polysaccharides acted as a non-competitive inhibitor to α-glucosidase and inhibited glucose transport of digested starch from Caco-2 cells monolayer.

The inhibition mechanism of shitake mushroom polysaccharides (Lentinula edodes polysaccharides, LEP) against α-glucosidase was studied by enzyme kinetic assay, fluorescence quenching and molecular docking..

OncologyImmune supportEnergy & fatigue

Maitake · 2022 · Published Erratum · International journal of molecular medicine

[Corrigendum] Grifola frondosa polysaccharides induce breast cancer cell apoptosis via the mitochondrial-dependent apoptotic pathway.

Subsequently to the publication of the above paper, an interested reader drew to the authors' attention that, in Fig. 3B on p.

Reishi · 2022 · Abstract · Journal of animal science

113 Immunological Effects of Ganoderma Lucidum Supplementation in Canine Nutrition

Metadata-grounded summary: This abstract indexes research on Ganoderma lucidum in Journal of animal science in 2022. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

OncologyImmune supportLiver support

Niu-Chang-Chih · 2022 · Research Support, Non U.S. Gov'T · Aging

Antrodia Camphorata Polysaccharide activates autophagy and regulates NLRP3 degradation to improve liver injury-related inflammatory response.

This study illustrated the liver protection mechanism of ACP from the perspective of autophagy activation. ACP suppressed the inflammatory injury of KCs, and decreased the cell apoptosis rate..

OncologyImmune supportMetabolic healthGut & microbiome

Niu-Chang-Chih · 2022 · Abstract · Current developments in nutrition

Antrodia Camphorata Supplement in the Early Life Inhibits Intestinal Tumorigenesis Later in Young Adult APC1638N Mice

Abstract Objectives Colorectal cancer (CRC) is a critical burden in the U.S. with a temporal increase in incidence in young adults.

Immune supportRespiratory

Oyster Mushroom · 2022 · Brief Report · Frontiers in pediatrics

Beta-(1,3/1,6)-D-glucan from Pleurotus ostreatus in the prevention of recurrent respiratory tract infections: An international, multicentre, open-label, prospective study.

Preschool children are particularly susceptible to recurrent upper and lower respiratory tract infections due to their immune immaturity and other contributing factors..

Shiitake · 2022 · Journal Article · International journal of biological macromolecules

Effect of shiitake mushrooms polysaccharide and chitosan coating on softening and browning of shiitake mushrooms (Lentinus edodes) during postharvest storage.

We investigated the browning and softening of fresh Lentinula edodes (LE) coated with polysaccharides (LEP) isolated from LE stalks and stored at 4 °C for 15 days..

Immune supportRespiratory

Reishi · 2022 · Abstract · Free radical biology & medicine

Ganoderma lucidum extract, Lycopene, Sulforaphane, Royal Jelly and Resveratrol as a combination demonstrate antioxidant and anti-inflammatory effects in COVID-19

Metadata-grounded summary: This abstract indexes research on Ganoderma lucidum in Free radical biology & medicine in 2022. MycoData maps the paper to immune support, respiratory based on its title, species context, article metadata, and study classification..

OncologyImmune supportMetabolic health

Niu-Chang-Chih · 2022 · Research Support, Non U.S. Gov'T · Microbiology spectrum

Sexual Crossing, Chromosome-Level Genome Sequences, and Comparative Genomic Analyses for the Medicinal Mushroom Taiwanofungus Camphoratus (Syn. Antrodia Cinnamomea, Antrodia Camphorata).

Taiwanofungus camphoratus mushrooms are a complementary and alternative medicine for hangovers, cancer, hypertension, obesity, diabetes, and inflammation. Though Taiwanofungus camphoratus has attracted considerable biotechnological and pharmacological attention, neither classical genetic nor genomic approaches have….

Reishi · 2022 · Journal Article · Carbohydrate polymers

Structure identification of a polysaccharide in mushroom Lingzhi spore and its immunomodulatory activity.

Ganoderma lucidum spore serves as a well-known immunomodulatory functional food in Asia. The polysaccharides in G.

Reishi · 2021 · Published Erratum · Applied microbiology and biotechnology

Correction to: Antidepressant‑like effect of Ganoderma lucidum spore polysaccharide‑peptide mediated by upregulation of prefrontal cortex brain‑derived neurotrophic factor.

Metadata-grounded summary: This published erratum indexes research on Ganoderma lucidum in Applied microbiology and biotechnology in 2021. MycoData maps the paper to immune support, cognition & nerves based on its title, species context, article metadata, and study classification..

Lion's Mane · 2021 · Research Support, Non U.S. Gov'T · Scientific reports

Hericium erinaceus mycelium and its small bioactive compounds promote oligodendrocyte maturation with an increase in myelin basic protein.

Oligodendrocytes (OLs), myelin-producing glia in the central nervous system (CNS), produce a myelin extension that enwraps axons to facilitate action potential propagation..

Immune supportRespiratory

Chaga · 2015 · English Abstract · Voprosy virusologii

[Antiviral activity of aqueous extracts of the birch fungus Inonotus obliquus on the human immunodeficiency virus].

Fractions of aqueous and water-alcohol extracts of the birch fungus Inonotus obliquus have antiviral effect against the human immunodeficiency virus type 1 (HIV-1)..

Immune supportMetabolic healthLiver support

Maitake · 2015 · Research Support, Non U.S. Gov'T · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Experimental study on intervention effect of Grifola frondosa on nonalcoholic steatohepatitis].

To study the preventive effect of Grifola frondosa on nonalcoholic steatohepatitis (NASH). The rat model of NASH was established by feeding high-fat diets for 12 weeks and intervened with 0.5 g · kg(-1) · d(-1) and 1.0 g · kg(-1) · d(-1) of C.

Mesima · 2015 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

A novel polysaccharide from mycelia of cultured Phellinus linteus displays antitumor activity through apoptosis.

Two novel polysaccharides termed PLPS-1 and PLPS-2 were isolated from mycelia of cultured Phellinus linteus by hot water extraction, purified by DEAE-52 cellulose and Sephadex G-100 column chromatography, and structurally characterized by FTIR and NMR spectroscopy, GC-MS, periodate oxidation/Smith degradation, and….

Immune supportMetabolic health

Lion's Mane · 2015 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

A polysaccharide from cultured mycelium of Hericium erinaceus and its anti-chronic atrophic gastritis activity.

A polysaccharide named EP-1 was found by screening cultured mycelium of Hericium erinaceus, which was extracted and subjected to precipitation with ethanol, hollow-fiber ultrafiltration and ion-exchange chromatography..

Immune supportGut & microbiomeRespiratory

Enoki · 2015 · Research Support, Non U.S. Gov'T · Bioscience, biotechnology, and biochemistry

Alleviation of Dermatophagoides microceras-induced allergy by an immunomodulatory protein, FIP-fve, from Flammulina velutipes in mice.

Asthma is a major public health concern. Its greatest risk factor is house dust mite (HDM).

Lion's Mane · 2015 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

An evaluation system for characterization of polysaccharides from the fruiting body of Hericium erinaceus and identification of its commercial product.

An evaluation system including colorimetric assay with iodine and potassium iodide, HPSEC-MALLS-RID analysis, GC-MS analysis, and saccharide mapping based on PACE analysis was proposed for the identification and discrimination of commercial product of Hericium erinaceus based on the chemical characters of….

Maitake · 2015 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Antitumor and immunomodulatory activity of a water-soluble polysaccharide from Grifola frondosa.

Grifola frondosa has long been known and respected as a medically important fungus. This study investigated the characterization, antitumor and immunomodulatory activity of a polysaccharide named GP11 purified from G.

OncologyImmune supportEnergy & fatigueLiver support

Niu-Chang-Chih · 2015 · Research Support, Non U.S. Gov'T · PloS one

Apoptosis of Hepatocellular Carcinoma Cells Induced by Nanoencapsulated Polysaccharides Extracted from Antrodia Camphorata.

Antrodia camphorata is a well-known medicinal mushroom in Taiwan and has been studied for decades, especially with focus on anti-cancer activity. Polysaccharides are the major bioactive compounds reported with anti-cancer activity, but the debates on how they target cells still remain..

Snow Fungus · 2015 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Carboxymethylation of polysaccharides from Tremella fuciformis for antioxidant and moisture-preserving activities.

The carboxymethylated polysaccharide (CATP), which derived from water-insoluble crude Tremella fuciformis polysaccharide (ATP), was prepared. And then the antioxidant and moisture-preserving activities of the samples were investigated..

Lion's Mane · 2015 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Chemical Compositions and Macrophage Activation of Polysaccharides from Leon's Mane Culinary-Medicinal Mushroom Hericium erinaceus (Higher Basidiomycetes) in Different Maturation Stages.

We studied the effect of the maturation stage on the chemical compositions and macrophage activation activity of polysaccharides from the culinary-medicinal mushroom Hericium erinaceus..

OncologyImmune supportCognition & nerves

Snow Fungus · 2015 · Comparative Study · The American journal of Chinese medicine

Comparison of Immunomodulatory and Anticancer Activities in Different Strains of Tremella fuciformis Berk.

Tremella fuciformis Berk (TF) is a common edible and medicinal mushroom, and has long been used in food and in Chinese medicine. It possesses anticancer, anti-inflammation, anti-oxidative, and neuroprotective abilities..

Immune supportMetabolic health

Chaga · 2015 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Effect of chemicals on production, composition and antioxidant activity of polysaccharides of Inonotus obliquus.

Polysaccharides are important secondary metabolites from the medicinal mushroom Inonotus obliquus. Various fatty acids, surfactants and organic solvents as cell membrane-reorganizing chemicals were investigated for their stimulatory effects on the growth of fungal mycelium and production of exopolysaccharides (EPS)….

Immune supportCognition & nervesMetabolic health

Maitake · 2015 · Research Support, Non U.S. Gov'T · Pharmaceutical biology

Effects of Grifola frondosa non-polar bioactive components on high-fat diet fed and streptozotocin-induced hyperglycemic mice.

CONTEXT: Consumption of medicinal mushrooms for disease prevention and maintaining health has a very long history in Asia. Grifola frondosa (Fr) S.F.

Enoki · 2015 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Enzymatic and acidic degradation effect on intracellular polysaccharide of Flammulina velutipes SF-08.

The intracellular polysaccharide (IPS) from Flammulina velutipes SF-08 mycelia was isolated and degraded by enzyme and acid. IPS and its derivative were purified by DEAE-52 cellulose chromatography, and five fractions were obtained..

Maitake · 2015 · Research Support, Non U.S. Gov'T · Bioscience, biotechnology, and biochemistry

Functional polysaccharides from Grifola frondosa aqueous extract inhibit atopic dermatitis-like skin lesions in NC/Nga mice.

Grifola frondosa (GF), distributed widely in far east Asia including Korea, is popularly used as traditional medicines and health supplementary foods, especially for enhancing the immune functions of the body..

OncologyImmune supportEnergy & fatigueGut & microbiome

Lion's Mane · 2015 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Hericium erinaceus polysaccharide-protein HEG-5 inhibits SGC-7901 cell growth via cell cycle arrest and apoptosis.

HEG-5 is a novel polysaccharide-protein purified from the fermented mycelia of Hericium erinaceus CZ-2. The present study aims to investigate the effects of HEG-5 on proliferation, cell cycle and apoptosis of human gastric cancer cells SGC-7901..

Maitake · 2015 · Research Support, Non U.S. Gov'T · Chinese journal of natural medicines

Immunomodulatory activity of macromolecular polysaccharide isolated from Grifola frondosa.

The present study was designed to evaluate the immune-modulating effects of the polysaccharide from Grifola frondosa (GFP) by using mouse peritoneal macrophage and cytoxan (CTX) induced immunosuppression models..

Almond Mushroom · 2015 · Research Support, Non U.S. Gov'T · BioMed research international

Immunomodulatory effects of the Agaricus blazei Murrill-based mushroom extract AndoSan in patients with multiple myeloma undergoing high dose chemotherapy and autologous stem cell transplantation: a randomized, double blinded clinical study.

Forty patients with multiple myeloma scheduled to undergo high dose chemotherapy with autologous stem cell support were randomized in a double blinded fashion to receive adjuvant treatment with the mushroom extract AndoSan, containing 82% of Agaricus blazei Murrill (19 patients) or placebo (21 patients)..

Immune supportLiver support

Snow Fungus · 2015 · Research Support, Non U.S. Gov'T · Biotechnology letters

Oral vaccination of mice with Tremella fuciformis yeast-like conidium cells expressing HBsAg.

Tremella fuciformis yeast-like conidium (YLC) cells were transformed by co-cultivation with Agrobacterium cells harboring the hepatitis B surface antigen (HBsAg) gene construct under the control of the CaMV35S promoter. Integration of HBsAg DNA into the YLC genome was confirmed by PCR and dot-blot hybridization..

Immune supportMetabolic health

Turkey Tail · 2015 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Polysaccharides of Trametes versicolor Improve Bone Properties in Diabetic Rats.

This study investigates the effects of Trametes versicolor (L.:Fr.) Pilát (TVP, also known as Yunzhi) on bone properties in diabetic rats. Forty-five male Wistar rats (8 weeks old) were fed either a chow diet (control) or a high-fat diet throughout the study period of 28 days..

Enoki · 2015 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Preparation of the oligosaccharides derived from Flammulina velutipes and their antioxidant activities.

The oligosaccharides were prepared from Flammulina velutipes by hydrolysis of F. velutipes polysaccharides with hydrogen peroxide (H2O2).

Enoki · 2015 · Research Support, Non U.S. Gov'T · Antonie van Leeuwenhoek

Purification, characterization, antioxidant activity and anti-aging of exopolysaccharides by Flammulina velutipes SF-06.

The main objective of this work was to purify the exopolysaccharides (EPS) of Flammulina velutipes SF-06 and investigate the relationship between the different purified fractions and bioactive activity..

Chaga · 2015 · Research Support, Non U.S. Gov'T · Applied biochemistry and biotechnology

Stimulatory Agents Simultaneously Improving the Production and Antioxidant Activity of Polyphenols from Inonotus obliquus by Submerged Fermentation.

Polyphenols are important secondary metabolites from the edible and medicinal mushroom Inonotus obliquus. Both the rarity of I.

OncologyImmune supportMetabolic health

Mesima · 2015 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Structural features and antitumor activity of a novel polysaccharide from alkaline extract of Phellinus linteus mycelia.

A novel high molecular weight polysaccharide (PL-N1) was isolated from alkaline extract of the cultured Phellinus linteus mycelia. The weight average molecular weight (Mw) of PL-N1 was estimated at 343,000kDa.

Immune supportGut & microbiome

Chaga · 2015 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Synthesis and characterization of a new Inonotus obliquus polysaccharide-iron(III) complex.

A new Inonotus obliquus polysaccharide-iron(III) complex (IOPS-iron) was synthesized and characterized. The preparation conditions of IOPS-iron(III) were optimized and the physicochemical properties were characterized by physicochemical methods, scanning electron microscopy (SEM), electron paramagnetic resonance (EPR)….

OncologyImmune supportMetabolic healthLiver support

Niu-Chang-Chih · 2015 · Research Support, Non U.S. Gov'T · BioMed research international

The Ethanolic Extract of Taiwanofungus camphoratus (Antrodia camphorata) Induces Cell Cycle Arrest and Enhances Cytotoxicity of Cisplatin and Doxorubicin on Human Hepatocellular Carcinoma Cells.

Taiwanofungus camphoratus (synonym Antrodia camphorata) is a widely used medicinal fungus in the folk medicine of Taiwan with several pharmacological features such as anti-inflammatory, liver protection, antihypertensive, and antioxidative activities. The ethanolic extract of T..

Chaga · 2014 · Comparative Study · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Comparison of component from different species of Inonotus obliquus].

In this paper, water content, mineral element and active ingredient concentration on fifteen Inonotus obliquus which comes from all over the world were studied. In the aspect of water content, the free water content of Finnish birch was the highest, reaching 77.21%, significantly better than that of other strains..

Zhu Ling · 2014 · English Abstract · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Physicochemical properties of medicinal fungus Polyporus umbellatus sclerotial exudate].

This study was conducted to investigate the physicochemical properties of Polyporus umbellatus sclerotial exudate. Morphological characteristics of the sclerotia and its exudate were observed during different stages of sclerotial formation.

Maitake · 2014 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

A heteropolysaccharide, L-fuco-D-manno-1,6-α-D-galactan extracted from Grifola frondosa and antiangiogenic activity of its sulfated derivative.

The tumor growth and metastasis are angiogenesis dependent, thus blockade of angiogenesis is a promising approach for treatment of cancer. Herein we reported the structural and biological features of a novel water-soluble polysaccharide named GFPW from the fruit body of Grifola frondosa..

Enoki · 2014 · Research Support, Non U.S. Gov'T · Journal of immunology research

Activation effects of polysaccharides of Flammulina velutipes mycorrhizae on the T lymphocyte immune function.

Flammulina velutipes mycorrhizae have increasingly been produced with increasing of F. velutipes production.