MycoData

Medicinal fungi research database

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Immune support

Immune modulation, polysaccharides, beta-glucans, and host-response studies.

I.

Species records

Species record

Oyster Mushroom

Pleurotus ostreatus

Studies
1,947
Avg relevance
53
Latest
2026
Open record

Species record

Reishi · Lingzhi

Ganoderma lucidum

Studies
1,830
Avg relevance
60
Latest
2026
Open record

Species record

Turkey Tail · Yun Zhi

Trametes versicolor

Studies
1,828
Avg relevance
41
Latest
2026
Open record

Species record

Shiitake · Hua Gu

Lentinula edodes

Studies
1,766
Avg relevance
60
Latest
2026
Open record

Species record

Cordyceps · Scarlet Club

Cordyceps militaris

Studies
1,635
Avg relevance
67
Latest
2026
Open record

Species record

Cordyceps · Caterpillar Fungus

Ophiocordyceps sinensis

Studies
1,576
Avg relevance
59
Latest
2026
Open record

Species record

Almond Mushroom · ABM

Agaricus blazei

Studies
1,441
Avg relevance
54
Latest
2026
Open record

Species record

Enoki · Winter Mushroom

Flammulina velutipes

Studies
1,403
Avg relevance
47
Latest
2026
Open record

Species record

King Oyster · Eryngii

Pleurotus eryngii

Studies
1,278
Avg relevance
60
Latest
2026
Open record

Species record

Maitake · Hen of the Woods

Grifola frondosa

Studies
1,276
Avg relevance
48
Latest
2026
Open record

Species record

Snow Fungus · Silver Ear

Tremella fuciformis

Studies
1,052
Avg relevance
29
Latest
2026
Open record

Species record

Lion's Mane · Yamabushitake

Hericium erinaceus

Studies
862
Avg relevance
67
Latest
2026
Open record

Species record

Chaga

Inonotus obliquus

Studies
738
Avg relevance
65
Latest
2026
Open record

Species record

Mesima · Sanghwang

Phellinus linteus

Studies
722
Avg relevance
58
Latest
2026
Open record

Species record

Niu-Chang-Chih

Antrodia camphorata

Studies
496
Avg relevance
63
Latest
2026
Open record

Species record

Nameko · Nametake

Pholiota microspora

Studies
421
Avg relevance
29
Latest
2026
Open record

Species record

Yellow Morel

Morchella esculenta

Studies
392
Avg relevance
42
Latest
2026
Open record

Species record

Zhu Ling · Umbrella Polypore

Polyporus umbellatus

Studies
263
Avg relevance
55
Latest
2026
Open record

Species record

Wood Ear · Kikurage

Auricularia auricula-judae

Studies
254
Avg relevance
51
Latest
2026
Open record

Species record

Agarikon · Quinine Conk

Fomitopsis officinalis

Studies
47
Avg relevance
55
Latest
2026
Open record

Articles

7,168 results

Showing 3,0513,100 of 7,168

Medium relevance

Chaga · 2012 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Antioxidant activities of five polysaccharides from Inonotus obliquus.

Five polysaccharides (IOP1b, IOP2a, IOP2c, IOP3a and IOP4) were isolated and purified from Inonotus obliquus by DEAE-Sepharose fast flow and SepharoseCL-6B column chromatography..

Immune support
Medium relevance

Lion's Mane · 2012 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Antioxidant and hepatoprotective potential of endo-polysaccharides from Hericium erinaceus grown on tofu whey.

Three fractions of the endo-polysaccharides from the mycelium of Hericium erinaceus (HEP) grown on tofu whey were obtained by the fractional precipitation with gradient concentrations of ethanol (HEP40, HEP60 and HEP80)..

Immune supportLiver support
Medium relevance

Chaga · 2012 · Research Support, Non U.S. Gov'T · International journal of molecular sciences

Antioxidative properties of crude polysaccharides from Inonotus obliquus.

The mushroom Inonotus obliquus has been widely used as a folk medicine in Russia, Poland and most of the Baltic countries. In this study, water-soluble and alkali-soluble crude polysaccharides (IOW and IOA) were isolated from I..

Immune support
Medium relevance

Chaga · 2012 · Evaluation Study · Carbohydrate polymers

Antitumor and immunomodulatory activity of water-soluble polysaccharide from Inonotus obliquus.

The medicinal mushroom Inonotus obliquus has been used as a folk remedy for a long time in Russia and East-European countries to treat gastrointestinal cancer, cardiovascular disease and diabetes. In our study, a water-soluble polysaccharide (ISP2a) was successfully purified from I..

OncologyImmune supportMetabolic healthGut & microbiome
Medium relevance

Chaga · 2012 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Chemical modification and antioxidant activities of polysaccharide from mushroom Inonotus obliquus.

Chemical modification polysaccharides exerted potent biological property which was related to the physicochemical properties. In the present study, polysaccharides from Inonotus obliquus were modified by suflation, acetylation and carboxymethylation.

Immune support
Medium relevance

Chaga · 2012 · Research Support, Non U.S. Gov'T · Food chemistry

Chemical properties and antioxidant activity of exopolysaccharides fractions from mycelial culture of Inonotus obliquus in a ground corn stover medium.

The medicinal mushroom Inonotus obliquus has been a folk remedy for a long time in East-European and Asian countries. We first reported the enhancement in production and antioxidant activity of exopolysaccharides by I.

Immune support
Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Protein expression and purification

Gene cloning and recombinant expression of a novel fungal immunomodulatory protein from Trametes versicolor.

Homology-based cloning was used to obtain a new gene (named FIP-tvc) from the genomic DNA of the Chinese traditional medicinal mushroom Trametes versicolor. FIP-tvc is a member of the fungal immunomodulatory protein family, is composed of 336bp encoding 111 amino acids, and is highly homologous with other fungal….

OncologyImmune support
Medium relevance

Lion's Mane · 2012 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Hericium erinaceus mushroom extracts protect infected mice against Salmonella Typhimurium-Induced liver damage and mortality by stimulation of innate immune cells.

The present study investigated the antibacterial effect of four extracts from the fruitbody of the edible medicinal mushroom Hericium erinaceus (hot water extract, HWE; microwave/50% ethanol extract, MWE; acid extract, ACE; and alkaline extract, AKE) against murine salmonellosis..

Immune supportGut & microbiomeLiver support
Medium relevance

Lion's Mane · 2012 · Research Support, Non U.S. Gov'T · Immunopharmacology and immunotoxicology

Hericium erinaceus suppresses LPS-induced pro-inflammation gene activation in RAW264.7 macrophages.

The aim of this study was to investigate the anti-inflammatory properties of each fraction of Hericium erinaceus (HE). The ethanol extract from HE was partitioned with different solvents in the order of increasing polarity..

Immune supportEnergy & fatigue
Medium relevance

Mesima · 2012 · Research Support, Non U.S. Gov'T · BMC complementary and alternative medicine

Immunomodulatory effect of water soluble extract separated from mycelium of Phellinus linteus on experimental atopic dermatitis.

BACKGROUND: Complementary and alternative medicine (CAM) is becoming a popular treatment for modulating diverse immune disorders. Phellinus linteus (P.

OncologyImmune supportSkin & hydration
Medium relevance

Niu-Chang-Chih · 2012 · Comparative Study · Applied microbiology and biotechnology

In vitro and in vivo comparisons of the effects of the fruiting body and mycelium of Antrodia camphorata against amyloid β-protein-induced neurotoxicity and memory impairment.

Antrodia camphorata is a particular and precious medicinal mushroom, and its fruiting body was found to provide more efficient protection from oxidative stress and inflammation than its mycelium because of its higher content of triterpenoids, total phenols, and so on..

OncologyImmune supportCognition & nerves
Medium relevance

Niu-Chang-Chih · 2012 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

In vivo antitumor effects of 4,7-dimethoxy-5-methyl-1,3-benzodioxole isolated from the fruiting body of Antrodia camphorata through activation of the p53-mediated p27/Kip1 signaling pathway.

In this study, 4,7-dimethoxy-5-methyl-1,3-benzodioxole (SY-1) was isolated from three different sources of dried Antrodia camphorata (AC) fruiting bodies. AC is a medicinal mushroom that grows on the inner heartwood wall of Cinnamomum kanehirai Hay (Lauraceae), which is an endemic species that is used in Chinese….

OncologyImmune supportMetabolic healthGut & microbiome
Medium relevance

Maitake · 2012 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Isolation, purification and antioxidant activities of polysaccharides from Grifola frondosa.

The crude polysaccharides (GFP) were isolated from the fruiting bodies of Grifola frondosa and purified by DEAE cellulose-52 chromatography and Sephadex G-100 size-exclusion chromatography in that order. Three main fractions, GFP-1, GFP-2 and GFP-3, were obtained through the isolation and purification steps..

Immune supportLiver support
Medium relevance

Maitake · 2012 · Research Support, Non U.S. Gov'T · Inflammation

Pharmacological and pharmacokinetic studies with agaricoglycerides, extracted from Grifola frondosa, in animal models of pain and inflammation.

The objective of the present study was to demonstrate the anti-inflammatory and antinociceptive properties of agaricoglycerides of the fermented mushroom of Grifola frondosa (AGF)..

OncologyImmune supportEnergy & fatigue
Medium relevance

Niu-Chang-Chih · 2012 · Research Support, Non U.S. Gov'T · Nutrition (Burbank, Los Angeles County, Calif.)

Polysaccharides from extracts of Antrodia camphorata mycelia and fruiting bodies modulate inflammatory mediator expression in mice with polymicrobial sepsis.

OBJECTIVES: Antrodia camphorata (AC) is a traditional Chinese medicine, and the polysaccharides contained within AC (AC-PSs) are reported to possess various biological functions..

OncologyImmune supportRespiratory
Medium relevance

Snow Fungus · 2012 · Research Support, Non U.S. Gov'T · Journal of radiation research

Protective Effect of Polysaccharides Isolated from Tremella fuciformis against Radiation-induced Damage in Mice

WTF-B, a type of water-soluble homogeneous polysaccharide, was isolated and purified from Tremella Fuciformis. To investigate the radioprotective effect of WTF-B, we employed a 30-day survival assay.

Immune supportMetabolic healthGut & microbiome
Medium relevance

Zhu Ling · 2012 · Research Support, Non U.S. Gov'T · Glycobiology

Structure elucidation and immunological function analysis of a novel β-glucan from the fruit bodies of Polyporus umbellatus (Pers.) Fries.

β-Glucans derived from various sources such as yeast cell walls and medicinal mushrooms are considered as valuable biological response modifiers for their ability to enhance the activity of immune cells, aid in wound healing and help prevent infections..

Immune supportMetabolic healthSkin & hydration
Medium relevance

Maitake · 2012 · Research Support, Non U.S. Gov'T · Glycoconjugate journal

Structure of a β-glucan from Grifola frondosa and its antitumor effect by activating Dectin-1/Syk/NF-κB signaling.

A soluble homogeneous β-glucan, GFPBW1, with a molecular mass of 300 kDa was purified from the fraction of the fruit bodies of Grifola frondosa extracted with 5% NaOH..

OncologyImmune support
Medium relevance

Snow Fungus · 2012 · Research Support, Non U.S. Gov'T · Behavioural brain research

Tremella fuciformis enhances the neurite outgrowth of PC12 cells and restores trimethyltin-induced impairment of memory in rats via activation of CREB transcription and cholinergic systems.

The present study examined the effects of Tremella fuciformis (TF) on the learning and memory function and the neural activity in rats with trimethyltin (TMT)-induced memory deficits. The rats were administered saline or TF (TF 25, 50, 100 mg/kg, p.o.) daily for 21 days..

Immune supportCognition & nervesMetabolic health
Medium relevance

Chaga · 2011 · English Abstract · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Protective effects and mechanism of Inonotus obliquus on asthmatic mice].

OBJECTIVE: To explore the protective effects and mechanism of ethanol extract of Inonotus obliquus (EEIO) injection on asthmatic mice. METHOD: OVA was injected intraperitoneally and inhaled to produce the asthmatic model.

Immune supportRespiratory
Medium relevance

Niu-Chang-Chih · 2011 · Other · Evidence-based complementary and alternative medicine: eCAM

A Preclinical Evaluation of Antrodia camphorata Alcohol Extracts in the Treatment of Non-Small Cell Lung Cancer Using Non-Invasive Molecular Imaging.

This study was carried out to provide a platform for the pre-clinical evaluation of anti-cancer properties of a unique CAM (complementary and alternative medicine) agent, Antrodia camphorata alcohol extract (ACAE), in a mouse model with the advantageous non-invasive in vivo bioluminescence molecular imaging….

OncologyImmune supportRespiratory
Medium relevance

Niu-Chang-Chih · 2011 · Other · Evidence-based complementary and alternative medicine: eCAM

An Extract of Antrodia camphorata Mycelia Attenuates the Progression of Nephritis in Systemic Lupus Erythematosus-Prone NZB/W F1 Mice.

Antrodia camphorata is used in folk medicine for the treatment of inflammation syndromes and liver-related diseases in Taiwan. The goal of this study was to evaluate the efficacy of the mycelial extract of A.

OncologyImmune supportLiver support
Medium relevance

Niu-Chang-Chih · 2011 · Research Support, Non U.S. Gov'T · Acta pharmacologica Sinica

Antcin A, a steroid-like compound from Antrodia camphorata, exerts anti-inflammatory effect via mimicking glucocorticoids.

AIM: To determine the active ingredient of Niuchangchih (Antrodia camphorata) responsible for its anti-inflammatory effects and the relevant molecular mechanisms. METHODS: Five major antcins (A, B, C, H, and K) were isolated from fruiting bodies of Niuchangchih..

Immune support
Medium relevance

Mesima · 2011 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Anti-tumor effects of proteoglycan from Phellinus linteus by immunomodulating and inhibiting Reg IV/EGFR/Akt signaling pathway in colorectal carcinoma.

Proteoglycan (P1) purified from Phellinus linteus has been reported to have anti-disease activities. The objectives of our research were to determine the anti-tumor effect and possible mechanisms of P1 on human cancer cells..

OncologyImmune supportGut & microbiome
Medium relevance

Mesima · 2011 · Patent · journal metadata

COMPOSITION CONTAINING EXTRACTS OF FUSCOPORIA OBLIQUA, GANODERMA LUCIDUM AND PHELLINUS LINTEUS FOR PROMOTING THE PROLIFERATION OF HEMATOPOIETIC STEM CELLS

A composition for promoting the proliferation of hematopoietic stem cells, which contains mushroom extracts, and more particularly to a composition and functional food for promoting the proliferation of hematopoietic stem cells, which contain, as active ingredients, an Inonotus Obliquus extract, a Ganoderma Luciderm….

OncologyImmune support
Medium relevance

Mesima · 2011 · Patent · journal metadata

COMPOSITION CONTAINING EXTRACTS OF FUSCOPORIA OBLIQUA, GANODERMA LUCIDUM AND PHELLINUS LINTEUS FOR PROMOTING THE PROLIFERATION OF HEMATOPOIETIC STEM CELLS

The present invention relates to a composition for promoting the proliferation of hematopoietic stem cells, which contains mushroom extracts, and more particularly to a composition and functional food for promoting the proliferation of hematopoietic stem cells, which contain, as active ingredients, an Inonotus….

OncologyImmune support
Medium relevance

Mesima · 2011 · Research Support, Non U.S. Gov'T · Fish & shellfish immunology

Diet enriched with mushroom Phellinus linteus extract enhances the growth, innate immune response, and disease resistance of kelp grouper, Epinephelus bruneus against vibriosis.

The effect of diet supplemented with Phellinus linteus fed for 30 days was investigated in grouper Epinephelus bruneus challenged with Vibrio anguillarum, Vibrio harveyi, Vibrio alginolyticus, and Vibrio carchariae; infected and treated fish had a significantly higher percent weight gain and feed efficiency..

Immune supportRespiratory
Medium relevance

Niu-Chang-Chih · 2011 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Effects of Antrodia camphorata on alcohol clearance and antifibrosis in livers of rats continuously fed alcohol.

Alcoholic fatty liver disease (AFLD) is the result of an excessive or chronic consumption of alcohol. Nine male Wistar rats per group were randomly assigned to one of the following drinking treatments: a 20% (w/w) alcohol solution (ALC); a 20% (w/w) alcohol solution cotreated with 0.25 g silymarin/kg BW/day; or a 20%….

Immune supportLiver support
Medium relevance

Turkey Tail · 2011 · Dissertation · journal metadata

Effects of volatiles and stress on growth, enzyme activity and gene expression of trametes versicolor

Metadata-grounded summary: This dissertation indexes research on Trametes versicolor in 2011. MycoData maps the paper to oncology, immune support based on its title, species context, article metadata, and study classification..

OncologyImmune support
Medium relevance

Mesima · 2011 · Other · Evidence-based complementary and alternative medicine: eCAM

Filtrate of Phellinus linteus Broth Culture Reduces Infarct Size Significantly in a Rat Model of Permanent Focal Cerebral Ischemia.

Phellinus linteus, a natural growing mushroom, has been known to exhibit anti-tumor, anti-inflammatory, anti-allergic and anti-oxidant effects. Aiming to exploit the neuroprotective effects of P.

OncologyImmune supportCognition & nerves
Medium relevance

Zhu Ling · 2011 · Evaluation Study · The American journal of Chinese medicine

Inhibition of urinary bladder carcinogenesis by aqueous extract of sclerotia of Polyporus umbellatus fries and polyporus polysaccharide.

The study aimed to evaluate inhibition effect of sclerotia of Polyporus umbellatus Fries aqueous extract (SPUE) and polyporus polysaccharide (PPS) on bladder cancer, then to measure their effect on mRNA expression of glutathione S-transferase π (GSTPi) and NAD(P)H:quinone oxidoreductase 1 (NQO1) in female Fischer-344….

OncologyImmune support
Medium relevance

Lion's Mane · 2011 · Other · Evidence-based complementary and alternative medicine: eCAM

Peripheral Nerve Regeneration Following Crush Injury to Rat Peroneal Nerve by Aqueous Extract of Medicinal Mushroom Hericium erinaceus (Bull.: Fr) Pers. (Aphyllophoromycetideae).

Nerve crush injury is a well-established axonotmetic model in experimental regeneration studies to investigate the impact of various pharmacological treatments. Hericium erinaceus is a temperate mushroom but is now being cultivated in tropical Malaysia..

Immune supportCognition & nervesEnergy & fatigue
Medium relevance

Snow Fungus · 2011 · Research Support, Non U.S. Gov'T · Bioresource technology

pH-control modes in a 5-L stirred-tank bioreactor for cell biomass and exopolysaccharide production by Tremella fuciformis spore.

The effect of pH-control modes on cell growth and exopolysaccharide production by Tremella fuciformis was evaluated in a 5-L bioreactor. The results show that the maximal dry cell weight (DCW) and exopolysaccharide production were 23.57 and 4.48 g L⁻¹ in pH-stat fermentation, where the maximal specific growth rate….

Immune support
Medium relevance

Mesima · 2011 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Preparation of Black Hoof medicinal mushroom Phellinus linteus (Berk. et M.A. Curt.) Teng (Aphyllophoromycetideae) beta-glucan sulfate and in vitro tumor cell growth inhibitory activity.

Polysaccharide beta-glucans were extracted from the medicinal mushroom Phellinus linteus (Hymenochaetaceae, Aphyllophoromycetideae) and subjected to sulfation. Chemical modification of the beta-glucan was confirmed by structural analysis, and its biological properties were compared with those of native beta-glucan..

OncologyImmune supportRespiratory
Medium relevance

Niu-Chang-Chih · 2011 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Production of bioactive exopolysaccharides from bitter medicinal mushroom, Antrodia camphorata (M. Zang et C.H. Su) Sh.H. Wu et al. (Aphyllophoromycetideae) in submerged cultivation.

This study examines the effects of various fructose concentrations in media on the production and quality of bioactive exopolysaccharides (EPS) from Bitter medicinal mushroom, Antrodia camphorata in submerged cultures. The fructose in media of submerged cultures of A..

Immune support
Medium relevance

Maitake · 2011 · Comparative Study · Journal of agricultural and food chemistry

Profiling of hepatic gene expression of mice fed with edible japanese mushrooms by DNA microarray analysis: comparison among Pleurotus ostreatus, Grifola frondosa, and Hypsizigus marmoreus.

To compare and estimate the effects of dietary intake of three kinds of mushrooms (Pleurotus ostreatus, Grifola frondosa, and Hypsizigus marmoreus), mice were fed a diet containing 10-14% of each mushroom for 4 weeks. Triacylglycerol in the liver and plasma decreased and plasma cholesterol increased in the P..

Immune supportMetabolic healthLiver supportRespiratory
Medium relevance

Mesima · 2011 · Research Support, Non U.S. Gov'T · BMC cancer

Protein-bound polysaccharide from Phellinus linteus inhibits tumor growth, invasion, and angiogenesis and alters Wnt/β-catenin in SW480 human colon cancer cells.

BACKGROUND: Polysaccharides extracted from the Phellinus linteus (PL) mushroom are known to possess anti-tumor effects. However, the molecular mechanisms responsible for the anti-tumor properties of PL remain to be explored.

OncologyImmune supportGut & microbiome
Medium relevance

Turkey Tail · 2011 · Research Support, Non U.S. Gov'T · Science China. Life sciences

Purification and characterization of a novel immunomodulatory protein from the medicinal mushroom Trametes versicolor.

Bioactive proteins represent an important group of functional agents in medicinal mushrooms. Trametes versicolor (L.) Lloyd is a mushroom frequently used in traditional Chinese medicine for its anti-tumor and immunomodulatory activities.

OncologyImmune support
Medium relevance

Wood Ear · 2011 · Research Support, Non U.S. Gov'T · Biopolymers

The molecular structure and solution conformation of an acidic heteropolysaccharide from Auricularia auricula-judae.

A water soluble acidic heteropolysaccharide named WAF was isolated from Auricularia auricula-judae by extracting with 0.9% NaCl solution. By using gas chromatography, gas chromatography-mass spectrometry, and NMR, its chemical structure was determined to be composed of a backbone of α-(1→3)-linked D-mannopyranose….

Immune supportMetabolic health
Medium relevance

Niu-Chang-Chih · 2010 · Research Support, Non U.S. Gov'T · Immunology

Administration of polysaccharides from Antrodia camphorata modulates dendritic cell function and alleviates allergen-induced T helper type 2 responses in a mouse model of asthma.

Asthma is a chronic disease characterized by airway inflammation caused by the dysregulated production of cytokines secreted by allergen-specific type 2 T helper (Th2) cells. Antrodia camphorata is a commonly used fungus in Asian folk medicine, and A..

OncologyImmune supportRespiratory
Medium relevance

Mesima · 2010 · Research Support, Non U.S. Gov'T · Journal of medicinal food

An extract of Phellinus linteus grown on germinated brown rice inhibits inflammation markers in RAW264.7 macrophages by suppressing inflammatory cytokines, chemokines, and mediators and up-regulating antioxidant activity.

The immunomodulatory activity of an organic extract of Phellinus linteus grown on slightly germinated brown rice (PBR) was previously demonstrated. Here, we investigated the possible anti-inflammatory activity of the PBR extract by analyzing its effect on the expression of macrophage-derived cytokines, chemokines, and….

OncologyImmune supportEnergy & fatigueGut & microbiome
Medium relevance

Niu-Chang-Chih · 2010 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Analgesic effects and the mechanisms of anti-inflammation of ergostatrien-3beta-ol from Antrodia camphorata submerged whole broth in mice.

Ergostatrien-3beta-ol (ST1), an active and major ingredient from Antrodia camphorata (AC) submerged whole broth was evaluated for the analgesic and anti-inflammatory effects..

OncologyImmune supportLiver support
Medium relevance

Niu-Chang-Chih · 2010 · Research Support, Non U.S. Gov'T · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Antrodia camphorata suppresses lipopolysaccharide-induced nuclear factor-kappaB activation in transgenic mice evaluated by bioluminescence imaging.

In an earlier study, we found that Antrodia camphorata inhibited the production of lipopolysaccharide (LPS)-induced cytokines, inducible nitric oxide synthase, and cyclooxygenase-2 by blocking nuclear factor-kappaB (NF-kappaB) activation in cultured RAW 264.7 macrophages..

OncologyImmune supportEnergy & fatigueGut & microbiome
Medium relevance

Mesima · 2010 · Patent · journal metadata

COMPOSITION CONTAINING EXTRACTS OF FUSCOPORIA OBLIQUA, GANODERMA LUCIDUM AND PHELLINUS LINTEUS FOR PROMOTING THE PROLIFERATION OF HEMATOPOIETIC STEM CELLS

The present invention relates to a composition containing mushroom extracts for promoting the proliferation of hematopoietic stem cells, and more specifically to a composition having a proliferation-promotive effect on hematopoietic stem cells, wherein the composition contains active ingredients composed of extracts….

OncologyImmune support
Medium relevance

Turkey Tail · 2010 · Research Support, Non U.S. Gov'T · Journal of hazardous materials

Degradation of the drug sodium diclofenac by Trametes versicolor pellets and identification of some intermediates by NMR.

Degradation of diclofenac sodium, a nonsteroidal anti-inflammatory drug widely found in the aquatic environment, was assessed using the white-rot fungus Trametes versicolor. Almost complete diclofenac removal (> or = 94%) occurred the first hour with T..

Immune support
Medium relevance

Wood Ear · 2010 · Brief Report · Mycobiology

Development of Detection Methods for Cellulolytic Activity of Auricularia auricula-judae.

To obtain basic information on the detection of cellulolytic activity in Auricularia auricula-judae, the influences of dye reagent, pH, and temperature were assessed..

Immune support
Medium relevance

Mesima · 2010 · Research Support, Non U.S. Gov'T · International immunopharmacology

Evaluation of antidiabetic activity of polysaccharide isolated from Phellinus linteus in non-obese diabetic mouse.

Polysaccharide (PLP) isolated from Phellinus linteus inhibits tumor growth and metastasis by enhancing immune functions of macrophages, dendritic cells, NK cells, T cells, and B cells. Here, we report that PLP can inhibit the development of autoimmune diabetes in non-obese diabetic (NOD) mice..

OncologyImmune supportMetabolic health
Medium relevance

Yellow Morel · 2010 · Research Support, Non U.S. Gov'T · Bioresource technology

Extraction optimization and in vivo antioxidant activities of exopolysaccharide by Morchella esculenta SO-01.

Response surface methodology was used to optimize extraction parameters for Morchella esculenta SO-01 exopolysaccharide (EPS) produced during submerged culture. The optimum conditions for EPS extraction were predicted to be, concentration at 84.07 degrees C, precipitation for 22.19 h and pH 8.44, and EPS production….

Immune supportLiver support
Medium relevance

Maitake · 2010 · Research Support, Non U.S. Gov'T · Experimental & molecular medicine

Grifola frondosa water extract alleviates intestinal inflammation by suppressing TNF-alpha production and its signaling.

TNF-alpha is a major cytokine involved in inflammatory bowel disease (IBD). In this study, water extract of Grifola frondosa (GFW) was evaluated for its protective effects against colon inflammation through the modulation of TNF-alpha action..

OncologyImmune supportEnergy & fatigueGut & microbiome
Medium relevance

Turkey Tail · 2010 · Research Support, Non U.S. Gov'T · Journal of hazardous materials

Naproxen degradation test to monitor Trametes versicolor activity in solid-state bioremediation processes.

The white-rot fungus Trametes versicolor has been studied as a potential agent for the removal of environmental pollutants. For long-time solid-phase bioremediation systems a test is required to monitor the metabolic status of T.

Immune supportMetabolic health