MycoData
Medicinal fungi research database
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Immune support
Immune modulation, polysaccharides, beta-glucans, and host-response studies.
Species records
Species record
Oyster Mushroom
Pleurotus ostreatus
- Studies
- 1,947
- Avg relevance
- 53
- Latest
- 2026
Species record
Reishi · Lingzhi
Ganoderma lucidum
- Studies
- 1,830
- Avg relevance
- 60
- Latest
- 2026
Species record
Turkey Tail · Yun Zhi
Trametes versicolor
- Studies
- 1,828
- Avg relevance
- 41
- Latest
- 2026
Species record
Shiitake · Hua Gu
Lentinula edodes
- Studies
- 1,766
- Avg relevance
- 60
- Latest
- 2026
Species record
Cordyceps · Scarlet Club
Cordyceps militaris
- Studies
- 1,635
- Avg relevance
- 67
- Latest
- 2026
Species record
Cordyceps · Caterpillar Fungus
Ophiocordyceps sinensis
- Studies
- 1,576
- Avg relevance
- 59
- Latest
- 2026
Species record
Almond Mushroom · ABM
Agaricus blazei
- Studies
- 1,441
- Avg relevance
- 54
- Latest
- 2026
Species record
Enoki · Winter Mushroom
Flammulina velutipes
- Studies
- 1,403
- Avg relevance
- 47
- Latest
- 2026
Species record
King Oyster · Eryngii
Pleurotus eryngii
- Studies
- 1,278
- Avg relevance
- 60
- Latest
- 2026
Species record
Maitake · Hen of the Woods
Grifola frondosa
- Studies
- 1,276
- Avg relevance
- 48
- Latest
- 2026
Species record
Snow Fungus · Silver Ear
Tremella fuciformis
- Studies
- 1,052
- Avg relevance
- 29
- Latest
- 2026
Species record
Lion's Mane · Yamabushitake
Hericium erinaceus
- Studies
- 862
- Avg relevance
- 67
- Latest
- 2026
Species record
Chaga
Inonotus obliquus
- Studies
- 738
- Avg relevance
- 65
- Latest
- 2026
Species record
Mesima · Sanghwang
Phellinus linteus
- Studies
- 722
- Avg relevance
- 58
- Latest
- 2026
Species record
Niu-Chang-Chih
Antrodia camphorata
- Studies
- 496
- Avg relevance
- 63
- Latest
- 2026
Species record
Nameko · Nametake
Pholiota microspora
- Studies
- 421
- Avg relevance
- 29
- Latest
- 2026
Species record
Yellow Morel
Morchella esculenta
- Studies
- 392
- Avg relevance
- 42
- Latest
- 2026
Species record
Zhu Ling · Umbrella Polypore
Polyporus umbellatus
- Studies
- 263
- Avg relevance
- 55
- Latest
- 2026
Species record
Wood Ear · Kikurage
Auricularia auricula-judae
- Studies
- 254
- Avg relevance
- 51
- Latest
- 2026
Species record
Agarikon · Quinine Conk
Fomitopsis officinalis
- Studies
- 47
- Avg relevance
- 55
- Latest
- 2026
Articles
7,168 results
Showing 3,101–3,150 of 7,168
Chaga · 2010 · Research Support, Non U.S. Gov'T · Journal of microbiology and biotechnology
Optimization of hydroxyl radical scavenging activity of exo-polysaccharides from Inonotus obliquus in submerged fermentation using response surface methodology.
The objectives of this study were to investigate the effect of fermentation medium on the hydroxyl radical scavenging activity of exo-polysaccharides from Inonotus obliquus by response surface methodology. A two-level fractional factorial design was used to evaluate the effect of different components of medium..
Mesima · 2010 · Research Support, Non U.S. Gov'T · PloS one
Phellinus linteus extract sensitizes advanced prostate cancer cells to apoptosis in athymic nude mice.
Phellinus linteus (PL) mushroom possesses anti-tumor property. We previously reported that the treatment with PL caused cultured human prostate cancer cells to undergo apoptosis..
Maitake · 2010 · Research Support, Non U.S. Gov'T · Acta biochimica et biophysica Sinica
Prokaryotic expression, purification, and polyclonal antibody production of a hydrophobin from Grifola frondosa.
Hydrophobins are small fungal proteins that self-assemble spontaneously at hydrophilic-hydrophobic interfaces and change the polar nature of the surfaces to which they attach. A new hydrophobin gene hgfI was identified recently from the edible mushroom Grifola frondosa..
Niu-Chang-Chih · 2010 · Research Support, Non U.S. Gov'T · Cancer immunology, immunotherapy: CII
Promoting effect of Antrodia camphorata as an immunomodulating adjuvant on the antitumor efficacy of HER-2/neu DNA vaccine.
It is well known that DNA vaccines induce protective humoral and cell-mediated immune responses in several animal models. Antrodia camphorata (AC) is a unique basidiomycete fungus of the Polyporaceae family that only grows on the aromatic tree Cinnamomum kanehirai Hayata (Lauraceae) endemic to Taiwan..
Mesima · 2010 · Research Support, Non U.S. Gov'T · Phytotherapy research: PTR
The ethyl acetate extract of Phellinus linteus grown on germinated brown rice induces G0/G1 cell cycle arrest and apoptosis in human colon carcinoma HT29 cells.
It is well known that Phellinus linteus has a variety of biological functions, such as antitumor and immunomodulating activities. In our previous studies, we developed a P..
Niu-Chang-Chih · 2010 · Patent · journal metadata
WATER EXTRACT OF ANTRODIA CAMPHORATA FOR IMMUNOSTIMULATORY EFFECT AND PREPARATION METHOD THEREOF
A preparation method for a water extract of the fruiting body of Antrodia camphorata (ACW) is provided. The method includes steps of: (a) providing the fruiting body and (b) boiling the fruiting body in water to obtain the water extract.
Enoki · 2009 · English Abstract · Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
[Effect of Flammulina velutipes polysaccharides on production of cytokines by murine immunocytes and serum levels of cytokines in tumor-bearing mice].
OBJECTIVE: To study the effect of Flammulina velutipes polysaccharides (FVP) on the production of tumor necrosis factor alpha (TNF-alpha), interferon-gamma (INF-gamma) and interleukin 2 (IL-2) by murine immunocytes..
Maitake · 2009 · Research Support, Non U.S. Gov'T · Carbohydrate research
An unambiguous structural elucidation of a 1,3-beta-D-glucan obtained from liquid-cultured Grifola frondosa by solution NMR experiments.
Grifolan LE (GRN-LE), a purified beta-D-glucan, which is obtained from liquid-cultured Grifola frondosa, exhibits various biological activities, including antitumor effects. Significant progress has been made in the study of these effects..
Snow Fungus · 2009 · Research Support, Non U.S. Gov'T · Applied biochemistry and biotechnology
Effect of constant glucose feeding on the production of exopolysaccharides by Tremella fuciformis spores.
A fed-batch culture system with constant feeding (glucose 80 g L(-1), 0.25 ml min(-1)) was used to study the influence of glucose on cell dry weight and exopolysaccharides production from submerged Tremella fuciformis spores in a 5-L stirred-tank bioreactor..
Niu-Chang-Chih · 2009 · Research Support, Non U.S. Gov'T · The Chinese journal of physiology
Effects of Antrodia camphorata extracts on the viability, apoptosis, [Ca2+]i, and MAPKs phosphorylation of OC2 human oral cancer cells.
The effect of Antrodia camphorata (AC) on human oral cancer cells has not been explored. This study examined the effect of AC on the viability, apoptosis, mitogen-activated protein kinases (MAPKs) phosphorylation and Ca2+ regulation of OC2 human oral cancer cells..
Niu-Chang-Chih · 2009 · Research Support, Non U.S. Gov'T · Planta medica
New constituents with iNOS inhibitory activity from mycelium of Antrodia camphorata.
In continuing our investigation on the bioactive constituents of mycelium of Antrodia camphorata, antroquinonol B (1), 4-acetyl-antroquinonol B (2), 2,3-(methylenedioxy)-6-methylbenzene-1,4-diol (3) and 2,4-dimethoxy-6-methylbenzene-1,3-diol (4) along with antrodin D (5) were isolated by the guidance of an inducible….
Turkey Tail · 2009 · Research Support, U.S. Gov'T, Non P.H.S. · Bioresource technology
Oxidation of anthracene by immobilized laccase from Trametes versicolor.
The laccase of Trametes versicolor was immobilized on the functionalized nanoparticles SBA-15 with the average diameter less than 10 nm. Laccase mediated oxidations of anthracene (ANT) were investigated in the presence of two mediators, 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt (ABTS)….
Niu-Chang-Chih · 2009 · Patent · journal metadata
Protein ACA1 of antrodia camphorata
A new protein, named ACA1, has been isolated and purified from the medical fungi Antrodia camphorata using the technique of anion-exchange chromatography. ACA1, a glycoprotein with a molecular mass of 29 kDa, has a pI value of pH 5.3 and contains 118 amino acids in its peptide moiety..
Niu-Chang-Chih · 2009 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry
Purification, cloning, and functional characterization of a novel immunomodulatory protein from Antrodia camphorata (bitter mushroom) that exhibits TLR2-dependent NF-κB activation and M1 polarization within murine macrophages.
A new immunomodulatory protein, designated ACA, was purified from the mycelium extract of Antrodia camphorata, a well-known folk medicine bitter mushroom in Taiwan, and N-terminally sequenced..
Niu-Chang-Chih · 2008 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry
Anti-inflammatory activities of new succinic and maleic derivatives from the fruiting body of Antrodia camphorata.
Six new compounds, trans-3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]pyrrolidine-2,5-dione (1), trans-1-hydroxy-3-(4-hydroxyphenyl)-4-isobutylpyrrolidine-2,5-dione (2), cis-3-(4-hydroxyphenyl)-4-isobutyldihydrofuran-2,5-dione (3), 3-(4-hydroxyphenyl)-4-isobutyl-1H-pyrrole-2,5-dione (4),….
Niu-Chang-Chih · 2008 · Research Support, Non U.S. Gov'T · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association
Antrodia camphorata inhibits proliferation of human breast cancer cells in vitro and in vivo.
Antrodia camphorata (A. camphorata) has been shown to induce apoptosis in cultured human breast cancer cells (MDA-MB-231).
Niu-Chang-Chih · 2008 · Patent · journal metadata
Cyclohexenones from Antrodia Camphorata for use in the treatment of autoimmune disease
A compound of formula (1) as defined therein is obtained from Antrodia camphorata and may be used to treat autoimmune disease, in particular 4-hydroxy-2,3-dimethoxy-6- methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone..
Niu-Chang-Chih · 2008 · Research Support, Non U.S. Gov'T · The Chinese journal of physiology
Effects of antrodia camphorata on viability, apoptosis, and [Ca2+]i in PC3 human prostate cancer cells.
Antrodia camphorata (AC) has been used as a health supplement in Asia to control different cancers; however, the cellular mechanisms of its effects are unclear. The effect of AC on cultured human prostate cancer cells (PC3) has not been explored..
Maitake · 2008 · Patent · journal metadata
Grifola frondosa beta-dextran freeze-dried powder for injection
The invention relates to a freeze-dried powder for injection which is prepared by Beta-glucan that is extracted and separated by using Grifola frondosa mycelium and has the structure shown in the attached figure I and a preparation method thereof, which pertains to the technical field of medical preparations..
Chaga · 2008 · Research Support, Non U.S. Gov'T · Current microbiology
Identification of Inonotus obliquus and analysis of antioxidation and antitumor activities of polysaccharides.
Inonotus obliquus, a wild wood-decay fungus which grows on Betula trees in cool climates, has a variety of biological activities that the scientific community is paying more and more attention to. However, the research work is moving at a snail's pace..
Maitake · 2008 · Research Support, Non U.S. Gov'T · The American journal of Chinese medicine
Inhibitory Effect of TNF-alpha Produced by Macrophages Stimulated with Grifola frondosa Extract (ME) on the Growth of Influenza A/Aichi/2/68 Virus in MDCK Cells.
We investigated the inhibitory effect of the conditioned medium (CM) from P338D1 (D1) cells, a murine macrophage cell line, stimulated for 10 hours with a fixed dose (100 mug/ml) of the extracts from the fruit bodies of Grifola frondosa (ME) or its ultra filtration-based fractions (MFs), on the growth of influenza….
Zhu Ling · 2008 · Research Support, Non U.S. Gov'T · Bioorganic & medicinal chemistry letters
New anti-inflammatory ergostane-type ecdysteroids from the sclerotium of Polyporus umbellatus.
Bioassay-guided fractionation of the ethyl acetate extract from the sclerotium of Polyporus umbellatus resulted in the isolation of three new ergostane-type ecdysteroids, named polyporoid A (1), B (2), and C (3), together with five known ecdysteroids..
Niu-Chang-Chih · 2008 · Research Support, Non U.S. Gov'T · International immunopharmacology
Polysaccharides from Antrodia camphorata mycelia extracts possess immunomodulatory activity and inhibits infection of Schistosoma mansoni.
Antrodia camphorata (AC) is a commonly used fungus in folk medicine for the treatment of viral hepatitis and cancer. AC polysaccharides (AC-PS) are reported to possess anti-inflammatory, anti-hepatitis B virus, and anticancer activities..
Wood Ear · 2008 · Research Support, Non U.S. Gov'T · Biopolymers
Structure and chain conformation of beta-glucan isolated from Auricularia auricula-judae.
From Auricularia auricula-judae, a water soluble beta-D-glucan, named as AAG, was isolated by extraction with 70% ethanol/water solution. Its chemical structure was analyzed by gas chromatography (GC), gas chromatography-mass spectrometry (GC-MS), matrix-assisted laser desorption /ionization (MALDI)-time of flight….
Maitake · 2008 · Research Support, Non U.S. Gov'T · Bioresource technology
Study of mycelial growth and bioactive polysaccharide production in batch and fed-batch culture of Grifola frondosa.
The fermentation of Grifola frondosa was investigated in the shake flasks and a 5-L jar fermenter in batch and fed-batch modes. In the shake-flask experiments, the preferable mycelial growth and exopolysaccharide (EPS) production was observed at relatively low pH; maltose and glucose were preferred carbon sources for….
Turkey Tail · 2008 · Research Support, Non U.S. Gov'T · Journal of the Society for Integrative Oncology
Trametes versicolor mushroom immune therapy in breast cancer.
Data from multiple epidemiologic and clinical studies on immune effects of conventional cancer treatment and the clinical benefits of polysaccharide immune therapy suggest that immune function has a role in breast cancer prevention..
Maitake · 2007 · Research Support, Non U.S. Gov'T · Mikrobiologiia
[Isolation and characterization of lectin from the surface of Grifola frondosa (FR.) S.F. Gray mycelium].
For the first time, from the surface of the dikaryotic mycelium of the xylotrophic basidiomycete Grifola frondosa 0917 a lectin has been isolated with a molecular mass of 68 +/- 1 kDa, consisting of two subunits of 33-34 kDa each. The lectin is a hydrophilic glycoprotein with the protein: glycan ratio of 3: 1..
Zhu Ling · 2007 · English Abstract · Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
[The extraction and sulfation of polysaccharide from Polyporus umbellatus].
OBJECTIVE: To prepare and sulfate of polysaccharide from Polyporus umbellatus, and to compare the results of joined dispersant or not. METHODS: After purified, SEC-LLS was used to determine the molecular weight of polysaccharide.
Niu-Chang-Chih · 2007 · Research Support, Non U.S. Gov'T · Journal of biotechnology
A highly stable cambialistic-superoxide dismutase from Antrodia camphorata: expression in yeast and enzyme properties.
A cDNA encoding a putative superoxide dismutase (SOD) was identified in expressed sequence tags of Antrodia camphorata, a medicinal mushroom found only in Taiwan. The deduced protein was aligned with Mn-SODs and Fe-SODs from other organisms, this SOD showed greater homology to Mn-SOD.
Niu-Chang-Chih · 2007 · Research Support, Non U.S. Gov'T · Journal of natural products
Anti-inflammatory benzenoids from Antrodia camphorata.
Four new compounds, including three new benzenoids, antrocamphin A (1), antrocamphin B (2), and 2,3,4,5-tetramethoxybenzoyl chloride (3), and a new 1,3-dioxolan-2-one derivative, antrodioxolanone (4), together with 13 known compounds have been isolated from the fruiting body of Antrodia camphorata..
Maitake · 2007 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules
Chemical characteristics and immuno-modulating activities of exo-biopolymers produced by Grifola frondosa during submerged fermentation process.
The immuno-modulating activities and chemical characteristics of exo-biopolymer (EX-GF) produced by a submerged mycelial culture of Grifola frondosa were studied. The EX-GF was fractionated into EX-GF-Fr.I, II, and III by Sephadex G-100 gel chromatography..
Niu-Chang-Chih · 2007 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry
Chemical characterization and anti-inflammatory effect of polysaccharides fractionated from submerge-cultured Antrodia camphorata mycelia.
Five polysaccharide fractions (AC-1, AC-2, AC-3, AC-4, and AC-5) were obtained after systemic solvent extractions and precipitations from Antrodia camphorata mycelia with yields of 2.92, 10.38, 1.65, 0.34, and 1.64%, respectively..
Snow Fungus · 2007 · Research Support, Non U.S. Gov'T · Biological & pharmaceutical bulletin
Effect of Tremella fuciformis on the Neurite Outgrowth of PC12h Cells and the Improvement of Memory in Rats
We investigated the neuritogenic effects of Tremella fuciformis (TF), which has been valued in traditional Chinese medicine as a remedy with nutritive and tonic actions, on PC12h cells..
Chaga · 2007 · Research Support, Non U.S. Gov'T · Journal of medicinal food
Ethanol extract of Inonotus obliquus inhibits lipopolysaccharide-induced inflammation in RAW 264.7 macrophage cells.
Inonotus obliquus (Pers.:Fr.) Pil. is a white rot fungus that belongs to the family Hymenochaetaceae of Basidiomycetes.
Niu-Chang-Chih · 2007 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology
Evaluation of the anti-inflammatory and anti-proliferation tumoral cells activities of Antrodia camphorata, Cordyceps sinensis, and Cinnamomum osmophloeum bark extracts.
The extracts of chloroform (1) and methanol (2) from Antrodia camphorata (AC), and chloroform (3) and n-butanol (4) fractions of methanol extract from Cordyceps sinensis (CS), and hexane (5), ethyl acetate (6), and methanol (7) from Cinnamomum osmophloeum bark (CO) were evaluated for their anti-inflammatory as well as….
Lion's Mane · 2007 · Patent · journal metadata
Hericium erinaceus tea and its preparation method
A health-care hericium erinaceus tea for improving immunity, regulating the action of immune globulin, and preventing and treating the diseases in digestive tract is prepared from hedgehog hydnum, tea, ganoderma, champignon, edible fungus and liquiorice root through immersing, decocting, filtering, concentrating,….
Snow Fungus · 2007 · Research Support, Non U.S. Gov'T · Applied microbiology and biotechnology
Hypoglycemic effects of exopolysaccharides produced by mycelial cultures of two different mushrooms Tremella fuciformis and Phellinus baumii in ob/ob mice.
The anti-diabetic activities of the exopolysaccharides (EPS) produced by submerged mycelial culture of two different mushrooms, Tremella fuciformis and Phellinus baumii, in ob/ob mice were investigated..
Maitake · 2007 · Research Support, Non U.S. Gov'T · Toxicology in vitro: an international journal published in association with BIBRA
Induction of apoptosis in SGC-7901 cells by polysaccharide-peptide GFPS1b from the cultured mycelia of Grifola frondosa GF9801.
The biological function of GFPPS1b, a novel polysaccharide-peptide isolated from cultured mycelia of Grifola frondosa GF9801, was well investigated. GFPS1b has anti-tumor activity and can significantly inhibit the proliferation of SGC-7901 cells, whereas slightly influences the growth of human normal liver cell line….
Mesima · 2007 · Research Support, Non U.S. Gov'T · Molecular carcinogenesis
Modulation of lung cancer growth arrest and apoptosis by Phellinus Linteus.
The Phellinus Linteus (PL) mushroom has been shown to possess anti-tumor properties. Through influencing lymphocytes, PL indirectly augments the host's immune system against cancer cells.
Niu-Chang-Chih · 2007 · Patent · journal metadata
New protein (ACA1) of antrodia camphorata
A new protein, named ACA1, has been isolated and purified from the medical fungi Antrodia camphorata using the technique of anion-exchange chromatography. ACA1, a glycoprotein with a molecular mass of 29 kDa, has a pI value of pH 5.3 and contains 118 amino acids in its peptide moiety..
Snow Fungus · 2007 · Patent · journal metadata
NEW USAGE OF TREMELLA FUCIFORMIS HETEROPOLYSACCHARIDE OR EXTRACT THEREOF
The usage of Tremella fuciformis heteropolysaccharide or T. fuciformis heteropolysaccharideextract in preparation of medicaments, food or functional food for protectingor repairing gastric mucosa..
Snow Fungus · 2007 · Patent · journal metadata
NEW USAGE OF TREMELLA FUCIFORMIS HETEROPOLYSACCHARIDE OR EXTRACT THEREOF
The usage of Tremella fuciformis heteropolysaccharide or T. fuciformis heteropolysaccharide extract in preparation of medicaments, food or functional food for promoting the growth and/or propagation of beneficial bacterium, in preparation of medicaments, food or functional food for ameliorating constipation, in….
Mesima · 2007 · Research Support, Non U.S. Gov'T · British journal of cancer
Phellinus linteus activates different pathways to induce apoptosis in prostate cancer cells.
It is known that polysaccharides extracted from the Phellinus linteus (PL) mushroom possess antitumour activity. We previously have demonstrated that high doses of PL render murine or human lung cancer cells susceptible to apoptosis..
Maitake · 2007 · Research Support, Non U.S. Gov'T · Bioresource technology
Structural analysis of anti-tumor heteropolysaccharide GFPS1b from the cultured mycelia of Grifola frondosa GF9801.
A 21-kDa heteropolysaccharide, coded as GFPS1b, was obtained from the cultured mycelia of Grifola frondosa GF9801 by hot-water extraction, ethanol precipitation, and fractioned by DEAE Sepharose Fast-flow, followed by the purification with Sephadex G-100 column chromatography using an AKTA purifier..
Niu-Chang-Chih · 2007 · Research Support, Non U.S. Gov'T · Nutrition and cancer
Unique formosan mushroom Antrodia camphorata differentially inhibits androgen-responsive LNCaP and -independent PC-3 prostate cancer cells.
Antrodia camphorata (AC), a precious and unique folkloric medicinal mushroom enriched in polyphenolics, isoflavonoids, triterpenoids, and polysaccharides, has been diversely used in Formosa (Taiwan) since the 18th century..
Mesima · 2006 · Research Support, Non U.S. Gov'T · International immunopharmacology
Acidic polysaccharide from Phellinus linteus inhibits melanoma cell metastasis by blocking cell adhesion and invasion.
The acidic polysaccharide (PL) from Phellinus linteus is an immunostimulator that has therapeutic activity against cancers. Here, we show that PL markedly inhibits melanoma cell metastasis in mice, and report that PL directly inhibits cancer cell adhesion to and invasion through the extracellular matrix, but that it….
Chaga · 2006 · Research Support, Non U.S. Gov'T · Life sciences
Anti-cancer effect and structural characterization of endo-polysaccharide from cultivated mycelia of Inonotus obliquus.
The endo-polysaccharide extracted from mycelia of Inonotus obliquus (Pers.:Fr.) Pil. (Hymenochaetaceae) is a specific activator of B cells and macrophages.
Mesima · 2006 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology
Heme oxygenase-1 mediates the anti-inflammatory effect of mushroom Phellinus linteus in LPS-stimulated RAW264.7 macrophages.
This work aimed to elucidate the anti-inflammatory mechanism of the n-BuOH subfraction (PL) prepared from fruiting bodies of Phellinus linteus. PL induced heme oxygenase-1 (HO-1) of the RAW264.7 macrophages in concentration- and time-dependent manner..
Maitake · 2006 · Research Support, Non U.S. Gov'T · Antiviral research
Inhibition of hepatitis B virus by D-fraction from Grifola frondosa: synergistic effect of combination with interferon-alpha in HepG2 2.2.15.
In this study, D-fraction extracted from Grifola frondosa (GF-D) and its combination with human interferon alpha-2b (IFN) were investigated for the inhibitory effect on hepatitis B virus (HBV) in HepG2 2.2.15 cells (2.2.15 cells)..
Mesima · 2006 · Research Support, Non U.S. Gov'T · Bioscience, biotechnology, and biochemistry
Partial Characterization and Immunostimulatory Effect of a Novel Polysaccharide–Protein Complex Extracted from Phellinus linteus
Many polysaccharides isolated from mushroom are considered to be biological response modifiers and have been shown to enhance various immune responses in vivo and in vitro. We demonstrate that a novel polysaccharide-protein complex (PPC) extracted from Phellinus linteus was a potent immunomodulator..