MycoData

Pleurotus ostreatus is one of the most cultivated mushrooms in the Czech Republic. The production of 1 kg of mushrooms generates about 5 kg of spent mushroom substrate.

High relevance

Lion's Mane · 2020 · Journal Article · International journal of biological macromolecules

Characterization of polysaccharides isolated from Hericium erinaceus and their protective effects on the DON-induced oxidative stress.

In this study, the structure characteristic of the Hericium erinaceus polysaccharide (HEP) was investigated using Fourier transformed infrared spectrometry (FT-IR), gas chromatography-mass spectrometry (GC-MS), gel permeation chromatography (GPC), methylation and nuclear magnetic resonance (NMR)..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Snow Fungus · 2020 · Journal Article · Mycoscience

Cloning and functional characterization of gpd and α-tubulin promoters from Annulohypoxylon stygium, a companion fungus of Tremella fuciformis

Annulohypoxylon stygium is an ascomycete that helps Tremella fuciformis produce the fruiting body in wild state or artificial cultivation. Although the interaction between these two fungi is well known, the underlying molecular mechanism is limited..

High relevance

Enoki · 2020 · Research Article · Microorganisms

Comparative Analysis of Carbohydrate Active Enzymes in the Flammulina velutipes var. lupinicola Genome.

The purpose of this study was to determine the genome sequence of Flammulina velutipes var. lupinicola based on next-generation sequencing (NGS) and to identify the genes encoding carbohydrate-active enzymes (CAZymes) in the genome..

Immune support

High relevance

Cordyceps · 2020 · Journal Article · Food research international (Ottawa, Ont.)

Comparative metabolic profiling of Ophiocordyceps sinensis and its cultured mycelia using GC–MS

Ophiocordyceps sinensis, one of the well-known traditional Chinese medicine, has multiple health-promoting effects. It is used as herbal remedy and health food in Asian countries, together with its cultured mycelia used as a substitute of natural O.

Metabolic health

High relevance

Shiitake · 2020 · Research Article · PeerJ

Comparative phosphoproteome analysis to identify candidate phosphoproteins involved in blue light-induced brown film formation in Lentinula edodes.

Light plays an important role in the growth and differentiation of Lentinula edodes mycelia, and mycelial morphology is influenced by light wavelengths. The blue light-induced formation of brown film on the vegetative mycelial tissues of L.

Immune support

High relevance

Cordyceps · 2020 · Research Article · PeerJ

Comparative transcriptome analysis revealed genes involved in the fruiting body development of Ophiocordyceps sinensis.

Ophiocordyceps sinensis is a highly valued fungus that has been used as traditional Asian medicine. This fungus is one of the most important sources of income for the nomadic populations of the Tibetan Plateau.

Energy & fatigue

High relevance

Chaga · 2020 · Research Article · Molecules (Basel, Switzerland)

Composition of Triterpenoids in Inonotus obliquus and Their Anti-Proliferative Activity on Cancer Cell Lines.

The objective of this study was to determine the composition of triterpenoids in the extracts from the inner and outer parts of Inonotus obliquus and to evaluate their anti-proliferative activity against cancer cell lines (HT-29, AGS, MCF-7, and PC3). Inner and outer parts of I..

Oncology

High relevance

Niu-Chang-Chih · 2020 · Research Article · AMB Express

Comprehensive transcriptomic and proteomic analyses of antroquinonol biosynthetic genes and enzymes in Antrodia camphorata.

Antroquinonol (AQ) has several remarkable bioactivities in acute myeloid leukaemia and pancreatic cancer, but difficulties in the mass production of AQ hamper its applications. Currently, molecular biotechnology methods, such as gene overexpression, have been widely used to increase the production of metabolites..

Oncology

High relevance

Snow Fungus · 2020 · Journal Article · International journal of biological macromolecules

Degradation of Tremella fuciformis polysaccharide by a combined ultrasound and hydrogen peroxide treatment: Process parameters, structural characteristics, and antioxidant activities.

The degradation effect of ultrasound (US)/hydrogen peroxide (H2O2) on Tremella fuciformis polysaccharide (TFP) were studied. The main process parameters of degradation were evaluated and the structural changes and antioxidant activities of TFP before and after US/H2O2 were analyzed..

Immune supportEnergy & fatigue

High relevance

Enoki · 2020 · Research Article · Journal of animal science and biotechnology

Determination of the available energy values and amino acid digestibility of Flammulina velutipes stem waste and its effects on carcass trait and meat quality fed to growing-finishing pigs.

BACKGROUND: Flammulina velutipes stem waste (FVS) is the by-product of mushroom industry. The objectives of this study were to determine the available energy and amino acid digestibility of FVS fed to pigs, and to evaluate the effects of dietary FVS inclusion on growth performance, biochemical profile of serum, fecal….

Cognition & nervesEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Yellow Morel · 2020 · Journal Article · International journal of medicinal mushrooms

Dichloromethane Extract of Fermentation Broth by Co-Culture of Morchella esculenta and Coprinus comatus Induces Apoptosis in U251 Cells via Mitochondrial Intrinsic Pathway.

The current study was designed to investigate the inhibitory effects of dichloromethane extract of fermentation broth by co-culture of Morchella esculenta and Coprinus comatus (DCMM) on human glioma U251 cells in vitro and its possible underlying mechanisms..

OncologyEnergy & fatigue

High relevance

Oyster Mushroom · 2020 · Journal Article · International journal of medicinal mushrooms

Dietary Fiber Contents and Its Fermentability In Vitro of Pleurotus ostreatus cv. Florida Mycelia (Agaricomycetes).

Oyster mushrooms (Pleurotus spp.) constitute a substantial resource for functional food, as they are commercially cultivated worldwide and assumed to contain beneficial fiber. The objective of this study was to characterize and analyze the mycelia of Pleurotus ostreatus cv..

Gut & microbiome

High relevance

Oyster Mushroom · 2020 · Research Article · Biotechnology reports (Amsterdam, Netherlands)

Effect of bioactive compounds extracted from Cordyceps nidus ANDES-F1080 on laccase activity of Pleurotus ostreatus ANDES-F515.

Laccases are ligninolytic enzymes produced by different microorganisms, especially by fungi such as the white-rot fungus Pleurotus ostreatus. Chemical inductors have been used to promote laccase secretion due to the application of these enzymes in lignocellulosic biomass pretreatment..

High relevance

Chaga · 2020 · Journal Article · Applied biochemistry and biotechnology

Effect of Colloidal Metal Nanoparticles on Biomass, Polysaccharides, Flavonoids, and Melanin Accumulation in Medicinal Mushroom Inonotus obliquus (Ach.:Pers.) Pilát.

The article explores effect of colloidal nanoparticles (NPs) of Ag, Fe, and Mg metals on the growth activity of the medicinal mushroom Inonotus obliquus (Ach.:Pers.) Pilát and the synthesis of biologically active compounds (polysaccharides, flavonoids, and melanins)..

Immune supportSkin & hydration

High relevance

Oyster Mushroom · 2020 · Journal Article · Journal of the science of food and agriculture

Effect of cultivating Pleurotus ostreatus on substrates supplemented with herb residues on yield characteristics, substrates degradation, and fruiting bodies' properties.

BACKGROUND: Inappropriate disposal of herb residues in China has caused major problems for the immediate environment and to human safety. Here, three herb residues, compound Kushen injection (CKI), Qizhi Tongluo capsule (QTC), and Shenbai Shuxin capsule (SSC), were applied as substrates to corncob at various ratios….

Immune supportEnergy & fatigue

High relevance

Enoki · 2020 · Journal Article · Food & function

Effects of a β-type glycosidic polysaccharide from Flammulina velutipes on anti-inflammation and gut microbiota modulation in colitis mice.

Using the Flammulina velutipes polysaccharide (FVP) extracted from our previous study, herein, we investigated the improvement of this starch-free β-type glycosidic polysaccharide in alleviating dextran sodium sulfate-induced ulcerative colitis (UC) in mice..

Immune supportMetabolic healthGut & microbiome

High relevance

Shiitake · 2020 · Journal Article · International journal of biological macromolecules

Effects of freeze drying and hot-air drying on the physicochemical properties and bioactivities of polysaccharides from Lentinula edodes.

Fresh Lentinula edodes were dried using two process technologies-freeze drying (FD) and hot-air drying (HD). The physicochemical, antioxidant and immunomodulatory properties of purified polysaccharides from dried L.

Immune supportMetabolic health

High relevance

Cordyceps · 2020 · Journal Article · Archives of microbiology

Effects of fungus-host associations on nucleoside differences among Ophiocordyceps sinensis populations on the Qinghai-Tibet Plateau of China.

Nucleosides are active components in Ophiocordyceps sinensis. All individual nucleoside contents in both fruiting and caterpillar bodies were significantly different among the 24 O.

High relevance

Lion's Mane · 2020 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Effects of Hericium erinaceus Mycelium Extracts on the Functional Activity of Purinoceptors and Neuropathic Pain in Mice with L5 Spinal Nerve Ligation.

Neuropathic pain is a serious clinical problem that is difficult to treat. Purinoceptors (P2Rs) transduce pain perception from the peripheral to the central nervous system and play an important role in the transmission of neuropathic pain signals..

OncologyImmune supportCognition & nerves

High relevance

Shiitake · 2020 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Effects of low-dose γ-irradiation on the water state of fresh Lentinula edodes

Understanding the water state in fresh Lentinula edodes under low-dose irradiation will be helpful to evaluate the freshness and forecast the shelf-life. In this study, the effects of low-dose γ-irradiation (1.0 and 2.0 kGy) on the water state of L.

High relevance

Shiitake · 2020 · Research Article · RSC advances

Effects of mixed agro-residues (corn crop waste) on lignin-degrading enzyme activities, growth, and quality of Lentinula edodes.

Using agro-residues in bioreactors to produce mushrooms is an important component of eco-agriculture. Here, we tested the cultivation of Lentinula edodes with corn cob (CC) and corn straw (CS), and then evaluated the resulting enzyme activities, agronomic traits, textures and nutrient compositions of mushrooms..

Gut & microbiome

High relevance

Oyster Mushroom · 2020 · Research Article · Journal of applied glycoscience

Effects of Phosphoryl Oligosaccharides of Calcium (POs-Ca) on Mycelial Growth and Fruiting Body Development of the Edible Mushroom, Pleurotus ostreatus.

Phosphoryl oligosaccharides of calcium (POs-Ca) is a calcium salt of phosphoryl maltooligosaccharides made from potato starch. POs-Ca is highly water-soluble and can supply both the calcium ion and acidic oligosaccharides in an aqueous solution..

High relevance

Almond Mushroom · 2020 · Clinical Trial Protocol · Trials

Effects of Transcranial Direct Current Stimulation (tDCS) and Approach Bias Modification (ABM) training on food cravings in people taking antipsychotic medication.

BACKGROUND: Antipsychotic drug-induced weight gain puts individuals with schizophrenia at increased cardiometabolic risk. As a potential intervention for this problem, we describe the theoretical background and a protocol for a feasibility randomised controlled trial (RCT) of approach bias modification (ABM) training….

Cognition & nervesMetabolic health

High relevance

Oyster Mushroom · 2020 · Journal Article · Plants (Basel, Switzerland)

Efficacy of Mushroom Metabolites (Pleurotus ostreatus) as A Natural Product for the Suppression of Broomrape Growth (Orobanche crenata Forsk) in Faba Bean Plants.

Broomrape parasitism on faba bean (Vicia faba L.) is the most destructive factor for this crop in Egypt. Pot experiments were conducted during the two successive seasons 2017/2018 and 2018/2019 to study the mitigation of broomrape stress on faba bean using a ten-fold dilution of 10% (w/v) spent mushroom substrate….

Skin & hydration

High relevance

Oyster Mushroom · 2020 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Efficacy of Pleuran (β-Glucan from Pleurotus ostreatus) in the Management of Herpes Simplex Virus Type 1 Infection.

One of the highly prevalent viral pathogens among children and adults causing infection, clinically presenting as herpes labialis, is herpes simplex virus type 1 (HSV-1). The long-term administration of acyclovir, a standard regimen for therapy against HSV-1 infections, can cause viral resistance against this drug..

Immune supportRespiratory

High relevance

Oyster Mushroom · 2020 · Research Article · Molecules (Basel, Switzerland)

Elemental Content in Pleurotus ostreatus and Cyclocybe cylindracea Mushrooms: Correlations with Concentrations in Cultivation Substrates and Effects on the Production Process.

Few data exist about the effect of substrates' elemental content on the respective concentrations in cultivated mushrooms, on the degradation of lignocellulosics or on production parameters..

High relevance

Oyster Mushroom · 2020 · Journal Article · Food & function

Enhancing the nutritional profile and digestibility of lentil flour by solid state fermentation with Pleurotus ostreatus.

Lentils (Lens culinaris) present an excellent nutrient profile. However, the increasing displacement of legumes from the diet and the possible negative effects of the food matrix and antinutrient factors encourage the application of new strategies to improve nutrient digestibility and to produce food concepts that….

Gut & microbiome

High relevance

Oyster Mushroom · 2020 · Journal Article · International journal of medicinal mushrooms

Ergosterol Peroxide Isolated from Oyster Medicinal Mushroom, Pleurotus ostreatus (Agaricomycetes), Potentially Induces Radiosensitivity in Cervical Cancer.

Every year, more than 500,000 new cases of cervical cancer are reported, making it the fourth leading cause of cancer globally. Although human papillomavirus (HPV) vaccines show promise as a protective measure, HPV-related cancers remain a public health problem since the vaccines, which are only specific to certain….

OncologyImmune supportRespiratory

High relevance

Oyster Mushroom · 2020 · Journal Article · Environmental science and pollution research international

Experimental simulation of somatic and germ cell genotoxicity in male Mus musculus fed extracts of lead contaminated Pleurotus ostreatus (white rot fungi).

Exposure to lead (Pb) is a major risk factor in reproductive toxicity, somatic, and germ cell genotoxicity. Exposure via deteriorating Pb paints and contaminated air, soil, and water had been the primary routes..

High relevance

Turkey Tail · 2020 · Journal Article · Chemosphere

Exploring the degradation capability of Trametes versicolor on selected hydrophobic pesticides through setting sights simultaneously on culture broth and biological matrix.

Pesticides introduced inadvertently or deliberately into environment by global agricultural practices have caused growing public concern, therefore the search of approaches for elimination of such xenobiotics should be motivated..

Energy & fatigue

High relevance

Turkey Tail · 2020 · Journal Article · Current microbiology

Extracellular and Intracellular Polysaccharide Extracts of Trametes versicolor Improve Lipid Profiles Via Serum Regulation of Lipid-Regulating Enzymes in Hyperlipidemic Mice.

Trametes versicolor extracts have been shown to have health-promoting benefits in hypercholesterolemia, obesity, hepatic steatosis, and cardiovascular disease. However, hypolipidemic or the anti-hyperlipidemic effects of polysaccharide extracts of T.

Immune supportMetabolic healthLiver support

High relevance

Shiitake · 2020 · Research Article · 3 Biotech

Feasibility of the use of Lentinula edodes mycelium in terbinafine remediation.

A detailed understanding of the fate of xenobiotics introduced into the environment and the mechanisms involved in their biotransformation, biodegradation, and biosorption is essential to improve the efficiency of remediation techniques..

High relevance

Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms

Fruiting Bodies of Chinese Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycetes) Alleviate Diabetes-Associated Oxidative Stress.

Hyperglycemia-induced complications, the major causes of death in diabetes, are closely related to the elevated oxidative stress. Our previous study indicated that fruiting bodies of Ophiocordyceps sinensis attenuated polydipsia and hyperglycemia in diabetic rats..

Metabolic healthLiver support

High relevance

Shiitake · 2020 · Research Article · Journal of fungi (Basel, Switzerland)

Functional Analysis of a Novel ABL (Abnormal Browning Related to Light) Gene in Mycelial Brown Film Formation of Lentinula edodes.

Lentinula edodes is a globally important edible mushroom species that is appreciated for its medicinal properties as well as its nutritional value. During commercial cultivation, a mycelial brown film forms on the surface of the sawdust growth medium at the late vegetative stage..

High relevance

Almond Mushroom · 2020 · Research Article · BioMed research international

Genome Survey and Transcriptome Analysis on Mycelia and Primordia of Agaricus blazei.

Agaricus blazei, a type of edible straw-rotting mushroom with somewhat sweet taste and fragrance of almonds, has attracted considerable scientific and practical attention. High-throughput Illumina PE150 and PacBio RSII platform were employed to generate a genomic sequence..

Immune support

High relevance

Oyster Mushroom · 2020 · Research Article · PeerJ

Genome-wide characterization of the Zn(II)2Cys6 zinc cluster-encoding gene family in Pleurotus ostreatus and expression analyses of this family during developmental stages and under heat stress.

Pleurotus ostreatus is one of the most widely cultivated mushrooms in China. The regulatory mechanisms of fruiting body formation and the response to heat stress in P.

High relevance

Cordyceps · 2020 · Research Article · Chinese medicine

Genomic analyses reveal evolutionary and geologic context for the plateau fungus Ophiocordyceps sinensis.

BACKGROUND: Ophiocordyceps sinensis, which is only naturally found in the high-elevation extreme environment of the Tibetan Plateau, has been used in traditional Chinese medicine. Information concerning the evolutionary and geologic context of O.

High relevance

Mesima · 2020 · Journal Article · International journal of biological macromolecules

Hepatoprotective effect of Phellinus linteus mycelia polysaccharide (PL-N1) against acetaminophen-induced liver injury in mouse.

Edible and medicinal fungi are one of the major sources for extraction and identification of polysaccharides, which are important biological response modifiers with notable antitumor, hepatoprotective effect and other pharmacological activities..

OncologyImmune supportLiver support

High relevance

Lion's Mane · 2020 · Research Article · International journal of molecular sciences

Hericium Erinaceus Prevents DEHP-Induced Mitochondrial Dysfunction and Apoptosis in PC12 Cells.

Hericium Erinaceus (HE) is a medicinal plant known to possess anticarcinogenic, antibiotic, and antioxidant activities. It has been shown to have a protective effect against ischemia-injury-induced neuronal cell death in rats..

OncologyCognition & nervesEnergy & fatigueRespiratory

High relevance

Shiitake · 2020 · Research Article · Frontiers in microbiology

Heterologous Expression of Laccase From Lentinula edodes in Pichia pastoris and Its Application in Degrading Rape Straw.

Rape straw cannot be efficiently degraded and utilized by ruminants due to its severe lignification and complex cross-linked structure between fiber and lignin. The laccases can catalyze the inter-unit bond cleavage in lignin substrates..

High relevance

Shiitake · 2020 · Research Article · Frontiers in microbiology

Hsp40 Protein LeDnaJ07 Enhances the Thermotolerance of Lentinula edodes and Regulates IAA Biosynthesis by Interacting LetrpE.

Our previous study found that LeDnaJ07 RNAi decreased Lentinula edodes resistance to heat stress and Trichoderma atroviride infection. In this study, the structure and function of the LeDnaJ07 gene was analyzed by gene cloning and overexpression in L..

High relevance

Maitake · 2020 · Journal Article · International journal of biological macromolecules

Hypoglycemic and hypolipidemic activities of Grifola frondosa polysaccharides and their relationships with the modulation of intestinal microflora in diabetic mice induced by high-fat diet and streptozotocin.

This study aimed to investigate the hypoglycemic and hypolipidemic activities of polysaccharides from Grifola frondosa (GFP) in diabetic mice induced by high-fat diet (HFD) and streptozotocin (STZ)..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Maitake · 2020 · Journal Article · International journal of biological macromolecules

Hypoglycemic and hypolipidemic mechanism of organic chromium derived from chelation of Grifola frondosa polysaccharide-chromium (III) and its modulation of intestinal microflora in high fat-diet and STZ-induced diabetic mice.

Polysaccharide from Grifola frondosa is an excellent metal-ion chelating agent owing to its distinctive structure and outstanding functional activities. Our previous research has successfully synthesized novel organic chromium derived from the chelation ofG.

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Cordyceps · 2020 · Journal Article · Applied microbiology and biotechnology

Identification of the genes involved in growth characters of medicinal fungus Ophiocordyceps sinensis based on Agrobacterium tumefaciens-mediated transformation.

Ophiocordyceps sinensis, one of the well-known and precious fungal species in the world, parasitizes soil-dwelling larvae of ghost moths on the Tibetan Plateau. The genetic intractability of this extremely psychrophilic and slow-growing O.

Energy & fatigueGut & microbiome

High relevance

Oyster Mushroom · 2020 · Research Article · Antioxidants (Basel, Switzerland)

Impact of Pleurotus ostreatus β-Glucans on Oxidative Stability of Active Compounds Encapsulated in Powders during Storage and In Vitro Digestion.

Polyunsaturated fatty acids and α-tocopherol were encapsulated in powders by spray drying using maltodextrins DE 12 as wall material and different emulsifiers (Tween®20, acacia gum or β-glucans-rich extracts from Pleurotus ostreatus)..

Gut & microbiome

High relevance

Turkey Tail · 2020 · Journal Article · Journal of environmental management

Improving laccase production from Trametes versicolor using lignocellulosic residues as cosubstrates and evaluation of enzymes for blue wastewater biodegradation.

Biocatalytic degradation of recalcitrant pollutants employing ligninolytic enzymes is a promising approach for wastewater treatment. However, enzymes production must be improved to make biodegradation a more cost-effective treatment..

High relevance

Turkey Tail · 2020 · Research Article · 3 Biotech

In vitro bioactivity, antimicrobial and anti-inflammatory efficacy of modified solvent evaporation assisted Trametes versicolor extract.

In the present study, modified solvent evaporation assisted methanolic Trametes versicolor extract was evaluated for its antimicrobial and anti-inflammatory efficacy..

Immune supportRespiratory

High relevance

Turkey Tail · 2020 · Journal Article · Wood Sci Technol

In vitro inhibition of extractives from knotwood of Scots pine (Pinus sylvestris) and black pine (Pinus nigra) on growth of Schizophyllum commune, Trametes versicolor, Gloeophyllum trabeum and Fibroporia vaillantii

The main goal of the study was to examine and compare the inhibition effect of knotwood extractives of Scots (Pinus sylvestris) and black pine (Pinus nigra) against the two white-rot fungi and two brown-rot fungi. Knotwood was extracted in a Soxhlet apparatus..

High relevance

Wood Ear · 2020 · Journal Article · International journal of medicinal mushrooms

Influence of Nigerian Jelly Ear Culinary-Medicinal Mushroom, Auricularia auricula-judae (Agaricomycetes), on Humoral and Cellular Immunity.

The fruiting body of Auricularia auricula-judae has received attention in folk medicine due to its possible medicinal values. Therefore, this study evaluated the immunomodulatory effects of the hot aqueous extract (AAAJ) and the β-D-glucan-rich polysaccharide fraction of A..

Immune support