MycoData

This study aimed to evaluate the effects of certain grain medium conditions, such as carbon and nitrogen source addition, water content, and initial pH, on the hispidin production of Phellinus linteus using solid-state fermentation..

High relevance

Chaga · 2020 · Journal Article · International journal of biological macromolecules

Inonotus obliquus polysaccharide ameliorates impaired reproductive function caused by Toxoplasma gondii infection in male mice via regulating Nrf2-PI3K/AKT pathway.

This study was carried out to investigate the effects of Inonotus obliquus polysaccharide (IOP) on impaired reproductive function and its mechanisms in Toxoplasma gondii (T. gondii)-infected male mice..

OncologyImmune supportEnergy & fatigue

High relevance

Chaga · 2020 · Journal Article · International journal of biological macromolecules

Inonotus obliquus polysaccharide protects against adverse pregnancy caused by Toxoplasma gondii infection through regulating Th17/Treg balance via TLR4/NF-κB pathway.

The study aimed to explore the protective effects of Inonotus obliquus polysaccharide (IOP) on adverse pregnancy caused by Toxoplasma gondii (T. gondii) infection and discover its potential mechanisms in pregnant mice..

OncologyImmune support

High relevance

Oyster Mushroom · 2020 · Journal Article · PloS one

Interruption of an MSH4 homolog blocks meiosis in metaphase I and eliminates spore formation in Pleurotus ostreatus.

Pleurotus ostreatus, one of the most widely cultivated edible mushrooms, produces high numbers of spores causing severe respiratory health problems for people, clogging of filters and spoilage of produce. A non-sporulating commercial variety (SPOPPO) has been successfully introduced into the market in 2006..

Respiratory

High relevance

Shiitake · 2020 · Journal Article · Journal of food composition and analysis

Investigation of differentiation of metal contents of Agaricus bisporus, Lentinula edodes and Pleurotus ostreatus sold commercially in Poland between 2009 and 2017

Agaricus bisporus, Pleurotus ostreatus and Lentinula edodes are the most commercially important mushroom species cultivated for human consumption. This study compared the content of major elements (ME) and trace elements (TE) in fruiting bodies of these three mushrooms available on the Polish market between 2009 and….

High relevance

Turkey Tail · 2020 · Journal Article · Journal of hazardous materials

Investigation of reactive Blue 19 biodegradation and byproducts toxicity assessment using crude laccase extract from Trametes versicolor.

Crude laccase potency on biodegradation and detoxification of Reactive blue 19 (RB-19) were demonstrated, along with prediction of degradation mechanisms, pathways and byproducts analysis..

High relevance

Lion's Mane · 2020 · Journal Article · International journal of biological macromolecules

Isolation and structural characterization of a novel polysaccharide from Hericium erinaceus fruiting bodies and its arrest of cell cycle at S-phage in colon cancer cells.

The fruiting body of Hericium erinaceus has been used to treat digestive system disorder-related diseases for over 2000 years in China. A novel polysaccharide, HEFP-2b, was obtained from H.

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Oyster Mushroom · 2020 · Journal Article · Microbiological research

Isolation of bacteria at different points of Pleurotus ostreatus cultivation and their influence in mycelial growth.

Pleurotus ostreatus is one of the most cultivated edible mushrooms worldwide and few approaches have been done to analyze bacterial influence during its cultivation..

Gut & microbiome

High relevance

Turkey Tail · 2020 · Journal Article · Journal of environmental management

Laccase production by Trametes versicolor in solid-state fermentation using tea residues as substrate and its application in dye decolorization.

An efficient valorization of tea residues into value-added product was developed by Trametes versicolor in solid-state fermentation (SSF). The laccase production of 25.7 U/g dry substrate was obtained by optimizing culture medium and condition, resulting in a 4.0-fold increase compared to that of 6.4 U/g dry substrate….

High relevance

Lion's Mane · 2020 · Journal Article · Carbohydrate polymers

Magnetic sensitive Hericium erinaceus residue chitin/Cu hydrogel nanocomposites for H2 generation by catalyzing NaBH4 hydrolysis.

In this study, a novel magnetic Hericium erinaceus residue chitin hydrogel was prepared and applied as template for in-situ synthesis of Cu nanoparticles, the prepared magnetic chitin/Cu hydrogel nanocomposites were further utilized as catalyst for H2 generation from NaBH4 hydrolysis..

High relevance

Zhu Ling · 2020 · Research Article · Frontiers in chemistry

Mechanisms of Macrophage Immunomodulatory Activity Induced by a New Polysaccharide Isolated From Polyporus umbellatus (Pers.) Fries.

Bladder cancer is one of the most malignant tumors closely associated with macrophage immune dysfunction. The Chinese medicine polyporus has shown excellent efficacy in treating bladder cancer, with minimal side effects.

OncologyImmune support

High relevance

Oyster Mushroom · 2020 · Journal Article · Bioresource technology

Metagenomic analysis revealed the succession of microbiota and metabolic function in corncob composting for preparation of cultivation medium for Pleurotus ostreatus.

Metagenomic sequencing was used to reveal the dynamic changes in microbiota and the metabolic functions in corncob composting for preparing cultivation medium of Pleurotus ostreatus. Results showed that the changes of physicochemical properties lead to different dominant phylum at different stages of composting..

Metabolic healthGut & microbiome

High relevance

Enoki · 2020 · Research Article · Foods (Basel, Switzerland)

Molecular Properties of Flammulina velutipes Polysaccharide-Whey Protein Isolate (WPI) Complexes via Noncovalent Interactions.

Whey protein isolate (WPI) has a variety of nutritional benefits. The stability of WPI beverages has attracted a large amount of attention.

Immune supportGut & microbiome

High relevance

Enoki · 2020 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Multiple fingerprint and fingerprint-activity relationship for quality assessment of polysaccharides from Flammulina velutipes.

Polysaccharides are known as one of the most important bioactive compounds in Flammulina velutipes. However, there is no accurate and comprehensive assessment method to evaluate and authenticate F.

Immune supportEnergy & fatigue

High relevance

Enoki · 2020 · Research Article · Frontiers in microbiology

Multiplex PCR for the Identification of Pathogenic Listeria in Flammulina velutipes Plant Based on Novel Specific Targets Revealed by Pan-Genome Analysis.

Listeria spp. is an important foodborne disease agent, often found in the fresh mushroom (Flammulina velutipes) and its production environment.

High relevance

Enoki · 2020 · Journal Article · Food chemistry

Nanocomposite packaging regulates extracellular ATP and programed cell death in edible mushroom (Flammulina velutipes).

Our previous study indicated that nanocomposite packaging material (Nano-PM) containing nano-Ag, nano-TiO2, nano-SiO2 and nanoattapulgite alleviated postharvest senescence of Flammulina velutipes by regulating respiration and energy metabolism..

Energy & fatigue

High relevance

Oyster Mushroom · 2020 · Journal Article · Anais da Academia Brasileira de Ciencias

Nephroprotective effect of Pleurotus ostreatus extract against cadmium chloride toxicity in rats.

Cadmium, present in the environment, accumulates in different organs of animals and humans, and has deleterious effects on the kidney. In this study, we investigated the protective effects of the methanolic extract of Pleurotus ostreatus in comparison with silymarin on renal function in cadmium-intoxicated rats for….

Energy & fatigue

High relevance

Lion's Mane · 2020 · Research Article · BMC complementary medicine and therapies

Neuroprotective effects of Hericium erinaceus (Bull.: Fr.) Pers. against high-dose corticosterone-induced oxidative stress in PC-12 cells.

BACKGROUND: Hericium erinaceus is a culinary and medicinal mushroom in Traditional Chinese Medicines. It has numerous pharmacological effects including immunomodulatory, anti-tumour, anti-microbial, anti-aging and stimulation of nerve growth factor (NGF) synthesis, but little is known about its potential role in….

OncologyImmune supportCognition & nervesEnergy & fatigue

High relevance

Enoki · 2020 · Journal Article · Journal of the science of food and agriculture

O/W Pickering emulsions stabilized by Flammulina velutipes polysaccharide nanoparticles as a fat substitute: the effects of phase separation on emulsified sausage's techno-functional and sensory quality.

BACKGROUND: The application of Pickering emulsion stabilized by food-derived particles is of great interest in the food field, including meat processing. However, the creaming phenomenon is a thorny problem and may impact the resulting product quality..

Immune supportSkin & hydration

High relevance

Enoki · 2020 · Journal Article · Journal of the science of food and agriculture

O/W Pickering emulsions stabilized by Flammulina velutipes polysaccharide nanoparticles as a fat substitute: the effects of phase separation on emulsified sausage's techno‐functional and sensory quality

BACKGROUND: The application of Pickering emulsion stabilized by food‐derived particles is of great interest in the food field, including meat processing. However, the creaming phenomenon is a thorny problem and may impact the resulting product quality..

Immune supportSkin & hydration

High relevance

Oyster Mushroom · 2020 · Journal Article · Food chemistry

Obtaining extracts rich in antioxidant polysaccharides from the edible mushroom Pleurotus ostreatus using binary system with hot water and supercritical CO2.

Pleurotus ostreatus is an edible mushroom with pharmacological potential, due to its metabolites, mainly polysaccharides. On here, the development of a new methodology for the recovery of extract rich in antioxidant polysaccharide was reported..

OncologyImmune support

High relevance

Lion's Mane · 2020 · Research Article · Foods (Basel, Switzerland)

Optimization of Ultrasonic Extraction to Obtain Erinacine A and Polyphenols with Antioxidant Activity from the Fungal Biomass of Hericium erinaceus.

Hericium erinaceus is a medicinal fungal species that produces the active biological metabolite erinacine A with strong antioxidant activity. The classical extraction techniques used to date to obtain metabolites from this fungal species require high consumption of resources and energy and, in the end, prove to be….

Cognition & nervesEnergy & fatigue

High relevance

Shiitake · 2020 · Journal Article · Food and Bioproducts Processing

Parametric characterization of the initial pH effect on the polysaccharides production by Lentinula edodes in submerged culture

Edible fungus Lentinula edodes (L. edodes) produces exo-polysaccharides (EPS), which have been obtained from submerged mycelia cultures.

Immune supportMetabolic health

High relevance

Lion's Mane · 2020 · Journal Article · Food & function

Peptides obtained from edible mushrooms: Hericium erinaceus offers the ability to scavenge free radicals and induce apoptosis in lung cancer cells in humans.

This research examined the antioxidant abilities of peptides derived from the Hericium erinaceus mushroom produced via three microbial proteases (Alcalase®, Neutrase®, and Flavourzyme®) at varying concentrations of 10, 25, and 50 mg mL-1. The H..

OncologyGut & microbiomeRespiratory

High relevance

Oyster Mushroom · 2020 · Journal Article · International journal of biological macromolecules

Physicochemical characterization and antitumor activity in vitro of a selenium polysaccharide from Pleurotus ostreatus.

Selenium-enriched polysaccharides have been gaining great attention for their antitumor activity in recent years. In this study, a novel selenium polysaccharide fraction (Se-POP-3) produced by Pleurotus ostreatus was characterized and its antitumor activity explored at cellular level..

OncologyImmune supportMetabolic health

High relevance

Turkey Tail · 2020 · Research Article · Molecules (Basel, Switzerland)

Plant Nitrilase Homologues in Fungi: Phylogenetic and Functional Analysis with Focus on Nitrilases in Trametes versicolor and Agaricus bisporus.

Fungi contain many plant-nitrilase (NLase) homologues according to database searches. In this study, enzymes NitTv1 from Trametes versicolor and NitAb from Agaricus bisporus were purified and characterized as the representatives of this type of fungal NLase..

High relevance

Lion's Mane · 2020 · Journal Article · International journal of biological macromolecules

Pre-protective effect of polysaccharides purified from Hericium erinaceus against ethanol-induced gastric mucosal injury in rats.

The β-glucan H6PC20 (Mw: 2390 kDa) and α-heteropolysaccharide HPB-3 (Mw: 15 kDa) were purified from the fruiting body of Hericium erinaceus according to the previous methods..

Immune support

High relevance

Maitake · 2020 · Journal Article · Carbohydrate polymers

Preparation and activities of selenium polysaccharide from plant such as Grifola frondosa

Selenium polysaccharide is an organic selenium compound formed by the combination of polysaccharide and selenium. The biological activity of selenium polysaccharide from plant such as Grifola frondosa is generally higher than that of selenium and polysaccharide, and it is more easily absorbed and utilized by human….

OncologyImmune supportSkin & hydration

High relevance

Snow Fungus · 2020 · Journal Article · Journal of food biochemistry

Preparation, characterization, and cytokine‐stimulating activity of oligosaccharides from Tremella fuciformis Berk

The Tremella fuciformis Berk polysaccharides (TP) have significant cytokine‐stimulating activity and low oral bioavailability owing to their large molecular volume..

Immune supportGut & microbiome

High relevance

Zhu Ling · 2020 · Journal Article · International journal of biological macromolecules

Preparation, physicochemical characterization, and anti-proliferation of selenium nanoparticles stabilized by Polyporus umbellatus polysaccharide.

Selenium nanoparticles (SeNPs), a novel selenium form, have attracted worldwide attention due to their bioactivities and low toxicity. This study aimed to assess the physicochemical characterization, storage stability, and anti-proliferative activities of SeNPs stabilized by Polyporus umbellatus polysaccharide (PUP)..

OncologyImmune supportEnergy & fatigue

High relevance

Oyster Mushroom · 2020 · Research Article · AMB Express

Production and composition of Pleurotus ostreatus cultivated on Lithovit®-Amino25 supplemented spent substrate.

Supplementation of the spent oyster substrate enhances its nutritional properties to produce a new mushroom cropping cycle. The study investigated the potential of a nano-fertilizer (Lithovit®-Amino25) with an admixture of 25% L-amino acids on Pleurotus ostreatus production, proteins, and amino acid contents..

High relevance

Enoki · 2020 · Journal Article · Bioscience, biotechnology, and biochemistry

Productivity and bioactivity of enokipodins A-D of Flammulina rossica and Flammulina velutipes.

Enokipodins are antimicrobial sesquiterpenes produced by Flammulina velutipes in a mycelial culture medium. To date, enokipodin production has not been reported in other members of the genus Flammulina.

Oncology

High relevance

Shiitake · 2020 · Journal Article · Waste management (New York, N.Y.)

Protaetia brevitarsis larvae can feed on and convert spent mushroom substrate from Auricularia auricula and Lentinula edodes cultivation.

The edible mushroom industry produces massive amounts of spent mushroom substrate (SMS). Thus, there is an urgent need for high-value utilization technology to process the SMS, especially SMSs originating from woodchips..

Gut & microbiome

High relevance

Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms

Protection against X-Ray Irradiation Injury by Chinese Caterpillar Medicinal Mushroom Ophiocordyceps sinensis (Ascomycetes) Polysaccharides in Mice.

Polysaccharides are one of the main active ingredients of Ophiocordyceps sinensis, a traditional Chinese medicinal mushroom. In this study, we investigated the protective effect of O.

Immune supportMetabolic health

High relevance

Niu-Chang-Chih · 2020 · Research Article · Nutrients

Protective Effect of Spore Powder of Antrodia camphorata ATCC 200183 on CCl4-Induced Liver Fibrosis in Mice.

Liver fibrosis is a pathological process with intrahepatic diffused deposition of the excess extracellular matrix, which leads to various chronic liver diseases. Drugs with high efficacy and low toxicity for liver fibrosis are still unavailable..

OncologyImmune supportEnergy & fatigueLiver support

High relevance

Mesima · 2020 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Protective Effects of Phellinus linteus Mycelium on the Development of Osteoarthritis after Monosodium Iodoacetate Injection.

OBJECTIVE: The aim of this study was to identify the protective effects of Phellinus linteus mycelium (PLM) and its possible mechanisms in a model of monosodium iodoacetate- (MIA-) induced osteoarthritis (OA)..

Immune supportMetabolic health

High relevance

Wood Ear · 2020 · Research Article · Frontiers in microbiology

Proteomic Analysis of Auricularia auricula-judae Under Freezing Treatment Revealed Proteins and Pathways Associated With Melanin Reduction.

Auricularia auricula-judae is an edible nutrient-rich mushroom, which is a traditional medicinal resource in China. It is known that environment stimuli will affect the production of melanin by A.

Skin & hydration

High relevance

Shiitake · 2020 · Journal Article · International journal of biological macromolecules

Recombinant Lentinula edodes xylanase improved the hydrolysis and in vitro ruminal fermentation of soybean straw by changing its fiber structure.

Soybean straw cannot be efficiently degraded and utilized by ruminants due to the complex cross-linked structure among cellulose, hemicellulose, and lignin in its cell wall..

Gut & microbiome

High relevance

Oyster Mushroom · 2020 · Research Article · Foods (Basel, Switzerland)

Reduction of Salt and Fat in Frankfurter Sausages by Addition of Agaricus bisporus and Pleurotus ostreatus Flour.

The reduction of fat and salt and the incorporation of fiber-rich compounds in frankfurters is a trend to improve their nutritional profile. The objective of this study was to evaluate the partial replacement of 30 and 50% of pork backfat and 50% of salt by adding edible mushroom flour (2.5 and 5%) from Agaricus….

High relevance

Maitake · 2020 · Journal Article · International journal of biological macromolecules

Regulatory effect of Grifola frondosa extract rich in polysaccharides and organic acids on glycolipid metabolism and gut microbiota in rats.

The present study investigated the composition of water extract of Grifola frondosa (GFWE) and its regulatory effects on glycolipid metabolism and gut microbiota in rats..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Lion's Mane · 2020 · Journal Article · International journal of biological macromolecules

Ricin B-like lectin orthologues from two mushrooms, Hericium erinaceus and Stereum hirsutum, enable recognition of highly fucosylated N-glycans.

The mushroom Hericium erinaceus contains isolectins, including the ricin B-like lectin HEL1 and the core 1 O-glycan-binding lectin HEL2. Recombinant HEL2 reportedly binds O-linked glycans, but recombinant HEL1 (rHEL1) has not been characterized..

OncologyCognition & nerves

High relevance

Cordyceps · 2020 · Research Article · IMA fungus

RIP mutated ITS genes in populations of Ophiocordyceps sinensis and their implications for molecular systematics.

Different hypotheses have been proposed to interpret the observed unusual ITS (internal transcribed spacer) sequences in Ophiocordyceps sinensis. The coexistence of diverged ITS paralogs in a single genome was previously shown by amplifying the ITS region from mono-ascospore isolates using specific primers designed….

High relevance

Niu-Chang-Chih · 2020 · Journal Article · Journal of the science of food and agriculture

RNA-Seq transcriptomic analyses of Antrodia camphorata to determine antroquinonol and antrodin C biosynthetic mechanisms in the in situ extractive fermentation.

BACKGROUND: In situ extractive fermentation (ISEF) is an important technique for improving metabolite productivity. The different extractants can induce the synthesis of different bioactive metabolites of Antrodia camphorata during ISEF.

High relevance

Niu-Chang-Chih · 2020 · Journal Article · Journal of the science of food and agriculture

RNA‐Seq transcriptomic analyses of Antrodia camphorata to determine antroquinonol and antrodin C biosynthetic mechanisms in the in situ extractive fermentation

High relevance

Lion's Mane · 2020 · Journal Article · Carbohydrate polymers

Smart pH/magnetic sensitive Hericium erinaceus residue carboxymethyl chitin/Fe3O4 nanocomposite hydrogels with adjustable characteristics

A smart hydrogel with pH/magnetic dual sensitivity was synthesized by in-situ synthesis of Fe₃O₄ inside carboxymethyl chitin hydrogel matrix prepared from Hericium erinaceus residue. The structure, pH/magnetic sensitivity, swelling and drug release behavior of the prepared hydrogels were investigated..

Gut & microbiome

High relevance

Lion's Mane · 2020 · Journal Article · Carbohydrate polymers

Smart pH/magnetic sensitive Hericium erinaceus residue carboxymethyl chitin/Fe3O4 nanocomposite hydrogels with adjustable characteristics.

A smart hydrogel with pH/magnetic dual sensitivity was synthesized by in-situ synthesis of Fe3O4 inside carboxymethyl chitin hydrogel matrix prepared from Hericium erinaceus residue. The structure, pH/magnetic sensitivity, swelling and drug release behavior of the prepared hydrogels were investigated..

Gut & microbiome

High relevance

Snow Fungus · 2020 · Journal Article · International journal of medicinal mushrooms

Structural Analysis and Antioxidant Activity of Extracellular Polysaccharides Extracted from Culinary-Medicinal White Jelly Mushroom Tremella fuciformis (Tremellomycetes) Conidium Cells.

Using Tremella fuciformis conidium cells for submerged fermentation is a cost-effective way to harvest bioactive compounds. In this study, we emphasized the structural and functional analysis of extracellular polysaccharides (EPS) extracted from T.

Immune supportMetabolic health

High relevance

Turkey Tail · 2020 · Research Article · Molecules (Basel, Switzerland)

Synthesis and Structure-Activity Relationship Studies of Hydrazide-Hydrazones as Inhibitors of Laccase from Trametes versicolor.

A series of hydrazide-hydrazones 1-3, the imine derivatives of hydrazides and aldehydes bearing benzene rings, were screened as inhibitors of laccase from Trametes versicolor..

High relevance

Lion's Mane · 2020 · Research Article · Journal of food science and technology

The effect of drying temperature on bioactive compounds and antioxidant activity of Leccinum scabrum (Bull.) Gray and Hericium erinaceus (Bull.) Pers.

In the study the effect of drying temperature on phenolic and organic acid content, total phenolic content, ergosterol content, antioxidant activity and content of 40 elements in fruiting bodies of Leccinum scabrum and Hericium erinaceus was estimated..

High relevance

Maitake · 2020 · Journal Article · Journal of food biochemistry

The hypoglycemic and renal protective effects of Grifola frondosa polysaccharides in early diabetic nephropathy

Grifola frondosa is a basidiomycete polypore fungus. Polysaccharides from G.

OncologyImmune supportEnergy & fatigueMetabolic health