MycoData

Aroma substances of mushrooms not only determine the qualitative characteristics of Basidiomycetes fruit bodies, but also exhibit medicinal properties. The chemical composition of the substrate for mushroom cultivation affects not only the growth processes and yield, but also is capable of causing the synthesis of….

High relevance

Chaga · 2020 · Journal Article · Applied biochemistry and biotechnology

The Influence of Submerged Fermentation of Inonotus obliquus with Control Atmosphere Treatment on Enhancing Bioactive Ingredient Contents.

This study led in the pioneering technique incubated in a bioreactor with the forced air injection system. The purpose of this study was to establish the optimal incubation conditions for this technique..

Energy & fatigue

High relevance

Lion's Mane · 2020 · Research Article · Frontiers in nutrition

The Inhibitory Effects of Hericium erinaceus β-glucan on in vitro Starch Digestion.

β-glucan has attracted extensive attention due to its health promoting effects, such as lowering the blood sugar and lipids levels, and enhancing immunity. In this study, three different β-glucans (HEBG-1, HEBG-2, HEBG-3) were obtained from Hericium erinaceus by sodium hydroxide, β-1,3-glucanase and β-1,6-glucanase,….

Immune supportMetabolic healthGut & microbiome

High relevance

Maitake · 2020 · Journal Article · Glycoconjugate journal

The preparation of a cold-water soluble polysaccharide from Grifola frondosa and its inhibitory effects on MKN-45 cells.

In this study, a novel water soluble polysaccharide (named GFP-4) was extracted from Grifola frondosa at 4 oC, and its preliminary structure and inhibitory effects on human gastric carcinoma MKN-45 cells through the Fas/FasL death receptor apoptosis pathway were investigated..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Turkey Tail · 2020 · Journal Article · The Science of the total environment

The removal of diuron from agricultural wastewaters by Trametes versicolor immobilized on pinewood in simple channel reactors.

The presence of pesticides in agricultural wastewater entails harmful risks to both the environment and public health. In this study, two channel-type bioreactors with Trametes versicolor immobilized on pinewood chips were evaluated in terms of the removal efficiency of diuron from agricultural wastewater under….

High relevance

Oyster Mushroom · 2020 · Journal Article · International journal of biological macromolecules

The ribotoxin-like protein Ostreatin from Pleurotus ostreatus fruiting bodies: Confirmation of a novel ribonuclease family expressed in basidiomycetes.

Fungi produce several toxins active against plants, animal or humans. Among them, ribotoxins are enzymes that specifically attack ribosomes irreparably compromising protein synthesis, useful as insecticides or as anticancer agents..

Oncology

High relevance

Maitake · 2020 · Journal Article · International journal of biological macromolecules

The role of Rho1 gene in the cell wall integrity and polysaccharides biosynthesis of the edible mushroom Grifola frondosa.

Grifola frondosa polysaccharides, especially β-glucans, showed the significant antitumor, hypoglycemic, and immune-stimulating activities. In the present study, a predominant regulatory subunit gfRho1p of β-1,3-glucan synthase in G..

OncologyImmune supportMetabolic health

High relevance

Oyster Mushroom · 2020 · Journal Article · IMA fungus

The saprotrophic Pleurotus ostreatus species complex: late Eocene origin in East Asia, multiple dispersal, and complex speciation.

The Pleurotus ostreatus species complex is saprotrophic and of significant economic and ecological importance. However, species delimitation has long been problematic because of phenotypic plasticity and morphological stasis..

High relevance

Turkey Tail · 2020 · Research Article · Frontiers in bioengineering and biotechnology

The Secretome of Phanerochaete chrysosporium and Trametes versicolor Grown in Microcrystalline Cellulose and Use of the Enzymes for Hydrolysis of Lignocellulosic Materials.

The ability of white-rot fungi to degrade polysaccharides in lignified plant cell walls makes them a suitable reservoir for CAZyme prospects. However, to date, CAZymes from these species are barely studied, which limits their use in the set of choices for biomass conversion in modern biorefineries..

Immune support

High relevance

Shiitake · 2020 · Research Article · Frontiers in microbiology

Transcriptomic Analysis of Two Lentinula edodes Genotypes With Different Cadmium Accumulation Ability.

Lentinula edodes, also known as Xiang'gu, is commonly eaten in cultures around the world. However, L.

High relevance

Maitake · 2020 · Journal Article · International journal of biological macromolecules

UDP-glucose pyrophosphorylase gene affects mycelia growth and polysaccharide synthesis of Grifola frondosa.

To elucidate potential roles of UDP-glucose pyrophosphorylase (UGP) in mycelial growth and polysaccharide synthesis of Grifola frondosa, a putative 2036-bp UDP-glucose pyrophosphorylase gene gfugp encoding a 53.17-kDa protein was cloned and re-annotated..

Immune supportMetabolic health

High relevance

Shiitake · 2020 · Research Article · ACS omega

Untargeted Metabolite Profiling of Antimicrobial Compounds in the Brown Film of Lentinula edodes Mycelium via LC-MS/MS Analysis.

The brown film (BF) of Lentinula edodes mycelium has been reported to exert biological activities during mushroom cultivation; however, to date, there is limited information on its chemical composition..

High relevance

Oyster Mushroom · 2020 · Journal Article · Molecules (Basel, Switzerland)

Use of a Pleurotus ostreatus Complex Cell Wall Extract as Elicitor of Plant Defenses: From Greenhouse to Field Trial.

Fungi constitute an abundant source of natural polysaccharides, some of them harboring original structures which can induce responses in mammalian or plant cells. An alkaline extract from the edible mushroom Pleurotus ostreatus has been obtained and called Pleuran complex cell wall extract (CCWE)..

Immune support

High relevance

Enoki · 2020 · Journal Article · International journal of biological macromolecules

Using Flammulina velutipes derived chitin-glucan nanofibrils to stabilize palm oil emulsion:A novel food grade Pickering emulsifier.

We herein report chitin-glucan nanofibrils from edible mushroom Flammulina velutipes (CGNFs) as a novel stabilizer for palm oil Pickering emulsion (o/w, 30:70, v:v). Generally, these CGNFs being composed of glucose and glucosamine, are threadlike with 4.9 ± 1.2 nm wide and 222.6 ± 91.9 nm long..

Metabolic health

High relevance

Oyster Mushroom · 2020 · Research Article · Scientifica

Valorization of Olive Pruning Residues through Bioconversion into Edible Mushroom Pleurotus ostreatus (Jacq. Ex Fr.) P. Kumm. (1871) of Improved Nutritional Value.

In several Mediterranean countries, olive pruning residues (OLPRs) are abandoned or burned leading to several environmental problems. Valorization of these agrowastes could be a challenge for the primary decomposer Pleurotus ostreatus, turning them into edible biomass..

Gut & microbiome

High relevance

Chaga · 2020 · Journal Article · Applied biochemistry and biotechnology

White rot fungus Inonotus obliquus pretreatment to improve tran-1,4-polyisoprene extraction and enzymatic saccharification of Eucommia ulmoides leaves.

This study proposes an innovative strategy of lignocellulose biodegradation by Inonotus obliquus under solid-state fermentation in extracting Eucommia ulmoides trans-1,4-polyisoprene (EUG) and producing reducing sugars efficiently. EUG and sugars were obtained through the white rot fungal pretreatment of E..

High relevance

Zhu Ling · 2019 · Journal Article · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[A landscape of transcriptome analysis of three sclerotia growth stages in Polyporus umbellatus].

Polyporus umbellatus,a traditional Chinese precious medicine as long been used for eliminating dampness,diuresis and have effect on cancer,getting more and more popularly in China recently. And the developmental metabolic process of the medicinal fungus,P.

OncologyMetabolic health

High relevance

Zhu Ling · 2019 · Journal Article · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Study on polysaccharide content and monosaccharide composition of Polyporus umbellatus from different production areas].

In order to provide scientific basics for exploitation and sufficient application of Polyporus umbellatus resources and study the monosaccharide composition of P. umbellatus polysaccharides,the anthrone-sulfuric acid method was applied to compare polysaccharide content of P.

Immune supportMetabolic health

High relevance

Lion's Mane · 2019 · Journal Article · International journal of biological macromolecules

A polysaccharide from cultured mycelium of Hericium erinaceus relieves ulcerative colitis by counteracting oxidative stress and improving mitochondrial function.

EP-1 is a polysaccharide with a molecular weight of approximately 3100 Da, which is extracted from the cultured mycelium of Hericium erinaceus. Its anti-ulcerative colitis activity was evaluated in experimental systems using rats with ulcerative colitis and Caco-2 cells as models for experimentation..

OncologyImmune supportEnergy & fatigueGut & microbiome

High relevance

Shiitake · 2019 · Journal Article · International journal of biological macromolecules

A protease-resistant α-galactosidase characterized by relatively acid pH tolerance from the Shitake Mushroom Lentinula edodes.

A monomeric α-galactosidase with a molecular weight of 64 kDa was purified from fresh fruiting bodies of Lentinula edodes. The purification protocol involved ion-exchange chromatography on DEAE-cellulose, CM-cellulose and Q-Sepharose and a final gel-filtration on Superdex 75..

Gut & microbiome

High relevance

Lion's Mane · 2019 · Research Article · Frontiers in microbiology

A Resequencing-Based Ultradense Genetic Map of Hericium erinaceus for Anchoring Genome Sequences and Identifying Genetic Loci Associated With Monokaryon Growth.

Hericium erinaceus has attracted tremendous interest owing to its compelling health-promoting properties. However, breeding of elite cultivars of H.

High relevance

Enoki · 2019 · Research Article · PeerJ

A second HD mating type sublocus of Flammulina velutipes is at least di-allelic and active: new primers for identification of HD-a and HD-b subloci.

BACKGROUND: Sexual development in Flammulina velutipes is controlled by two different mating type loci (HD and PR). The HD locus contains homeodomain (Hd) genes on two separate HD subloci: HD-a and HD-b..

High relevance

Lion's Mane · 2019 · Journal Article · International immunopharmacology

A unique polysaccharide from Hericium erinaceus mycelium ameliorates acetic acid-induced ulcerative colitis rats by modulating the composition of the gut microbiota, short chain fatty acids levels and GPR41/43 respectors.

Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disorder of the colonic mucosa. Risk of colorectal cancer in ulcerative colitis is increased in patients with long-standing disease compared with the general population..

OncologyImmune supportGut & microbiome

High relevance

Lion's Mane · 2019 · Research Article · Molecules (Basel, Switzerland)

Absolute Bioavailability, Tissue Distribution, and Excretion of Erinacine S in Hericium erinaceus Mycelia.

Erinacine S, so far known to have been produced only in Hericium erinaceus mycelia, has just recently been discovered and is able to reduce amyloid plaque growth and improve neurogenesis in aged brain of rats..

Cognition & nervesMetabolic healthGut & microbiomeLiver support

High relevance

Shiitake · 2019 · Research Article · Journal of clinical biochemistry and nutrition

Activation of NF-E2 p45-related factor-2 transcription and inhibition of intestinal tumor development by AHCC, a standardized extract of cultured Lentinula edodes mycelia.

It has been reported that activation of NF-E2 p45-related factor-2 (NRF2), a transcription factor, induces a variety of antioxidant enzymes, and plays an important role in preventing carcinogenesis. AHCC is a standardized extract of cultured Lentinula edodes mycelia and it has been demonstrated to improve cancer..

OncologyImmune supportGut & microbiome

High relevance

Snow Fungus · 2019 · Research Article · Mycobiology

An Enzymolysis-Assisted Agrobacterium tumefaciens-Mediated Transformation Method for the Yeast-Like Cells of Tremella fuciformis.

Agrobacterium tumefaciens-mediated transformation (ATMT), as a simple and versatile method, achieves successful transformation in the yeast-like cells (YLCs) of Tremella fuciformis with lower efficiency..

Gut & microbiomeSkin & hydration

High relevance

Shiitake · 2019 · Journal Article · Food Research International

Analysis of volatile compounds of Lentinula edodes grown in different culture substrate formulations

Volatile compounds of Lentinula edodes grown in different culture substrate (CS) formulations were analyzed to reveal (i) the relationship between volatile compound production and CS formulations, (ii) the contribution of volatile compounds to L..

High relevance

Maitake · 2019 · Journal Article · Applied biochemistry and biotechnology

Anti-Diabetic and Anti-Nephritic Activities of Grifola frondosa Mycelium Polysaccharides in Diet-Streptozotocin-Induced Diabetic Rats Via Modulation on Oxidative Stress.

Grifola frondosa is an edible fungus with a variety of potential pharmacological activities. This study investigates the hypoglycemic, anti-diabetic nephritic, and antioxidant properties of G.

Immune supportEnergy & fatigueMetabolic health

High relevance

Turkey Tail · 2019 · Journal Article · Natural product research

Anti-inflammatory activities of the chemical constituents isolated from Trametes versicolor.

Twenty-seven compounds including nine triterpenoids (1-9), eight sterols (10-17), two ribonucleotides (18, 19), four phenols (20-23), three glycosides (24-26), and one furan (27) were isolated from the fruiting bodies of Trametes versicolor (L.) Lloyd..

Immune support

High relevance

Mesima · 2019 · Journal Article · International journal of biological macromolecules

Anti-inflammatory activity of polysaccharides from Phellinus linteus by regulating the NF-κB translocation in LPS-stimulated RAW264.7 macrophages.

Inflammatory response remains one of the most common and serious complications of disease. In order to profound understanding relationship between Phellinus linteus polysaccharides (TCM) and inflammation, inflammatory cell model was constructed by LPS acting RAW264.7 cell line..

Immune support

High relevance

Yellow Morel · 2019 · Journal Article · International journal of biological macromolecules

Anti-inflammatory effects of Morchella esculenta polysaccharide and its derivatives in fine particulate matter-treated NR8383 cells.

Fine particulate matter (PM2.5) exposure could cause many acute and chronic respiratory diseases. In this study the protective effects of polysaccharide from Morchella esculenta (FMP-1) and its derivatives against PM2.5-induced inflammation were evaluated..

OncologyImmune supportEnergy & fatigueRespiratory

High relevance

Almond Mushroom · 2019 · Journal Article · Frontiers in bioscience (Elite edition)

Antiapoptotic role of Agaricus blazei extract in rodent model of Parkinson's disease.

Rotenone is a pesticide that has been shown to induce the pathological symptoms of Parkinson's disease (PD) in both cellular and animal models. In this study, we investigated the protective effect of Agaricus blazei extract on rotenone-induced dopaminergic degeneration and apoptosis in mice model.

OncologyCognition & nerves

High relevance

Niu-Chang-Chih · 2019 · Research Article · International journal of molecular sciences

Antidiabetic and Antihyperlipidemic Effects of Sulphurenic Acid, a Triterpenoid Compound from Antrodia camphorata, in Streptozotocin-Induced Diabetic Mice.

The present study was designed to evaluate the protective effect of sulphurenic acid (SA), a pure compound from Antrodia camphorata, on diabetes and hyperlipidemia in an animal model study and to clarify the underlying molecular mechanism..

Energy & fatigueMetabolic healthLiver support

High relevance

Lion's Mane · 2019 · Research Article · Molecules (Basel, Switzerland)

Array of Metabolites in Italian Hericium erinaceus Mycelium, Primordium, and Sporophore.

Hericium erinaceus is a medicinal mushroom that contains many molecules promising a plethora of therapeutic properties. In this study, the strain H.e.2 (MicUNIPV, University of Pavia, Italy) was isolated from a sporophore collected in Tuscany (Italy)..

Cognition & nerves

High relevance

Turkey Tail · 2019 · Journal Article · International journal of biological macromolecules

Biocatalytic characterization of free and immobilized laccase from Trametes versicolor in its activation zone.

This investigation may be of interest for researchers working on the determination of several biocatalytic properties of the laccase from Trametes versicolor. So, We will treated the effects of pH, temperature, several organic components and heavy metals by performing enzyme assays in the presence of a 2,6….

High relevance

Turkey Tail · 2019 · Journal Article · Industrial crops and products

Biological pretreatment with Trametes versicolor to enhance methane production from lignocellulosic biomass: a metagenomic approach

The presence of poorly biodegradable components in lignocellulosic biomass limits the methane recovery in anaerobic digesters. The main reason to go for aerobic pretreatment before anaerobic digestion (AD) is to enable enzymatic cleavage of the aromatic rings in lignin by oxygen since it cannot be efficiently degraded….

Energy & fatigueGut & microbiome

High relevance

Enoki · 2019 · Journal Article · International journal of food science & technology

Characteristic of polysaccharides from Flammulina velutipes in vitro digestion under salivary, simulated gastric and small intestinal conditions and fermentation by human gut microbiota

In this study, in vitro digestion and fermentation of Flammulina velutipes ‐derived polysaccharides (FVP) were investigated. It was found that FVP mainly consisted of 48.45% glucose, 15.40% mannose, 14.60% xylose, 11.80% fucose and 9.90% galactose..

Immune supportMetabolic healthGut & microbiome

High relevance

Shiitake · 2019 · Journal Article · International journal of biological macromolecules

Characteristics of a recombinant Lentinula edodes endoglucanase and its potential for application in silage of rape straw.

An experiment was conducted to determine the characteristics of recombinant endoglucanase and its effects on rape straw silage. The endoglucanase from Lentinula edodes (LeCel12A) was produced in Pichia pastoris and shown maximum activity at 40 °C and pH 3.0..

High relevance

Enoki · 2019 · Research Article · Antioxidants (Basel, Switzerland)

Characterization and Antioxidant Activities of Yellow Strain Flammulina velutipes (Jinhua Mushroom) Polysaccharides and Their Effects on ROS Content in L929 Cell.

Yellow strain Flammulina velutipes, which is known as Jinhua mushroom in Taiwan, has become popular among customers due to its distinct texture that is utterly different from white strain F. velutipes..

OncologyImmune supportEnergy & fatigueSkin & hydration

High relevance

Cordyceps · 2019 · Research Article · Molecules (Basel, Switzerland)

Characterization of Humic Substances in the Soils of Ophiocordyceps sinensis Habitats in the Sejila Mountain, Tibet: Implication for the Food Source of Thitarodes Larvae.

Humic substances in soil are considered to be an alternative food to the tender plant roots for Thitarodes larvae in the habitats of Ophiocordyceps sinensis in the Qinghai-Tibetan Plateau..

Energy & fatigue

High relevance

Turkey Tail · 2019 · Research Article · AMB Express

Characterization of recombinant laccase from Trametes versicolor synthesized by Arxula adeninivorans and its application in the degradation of pharmaceuticals.

Recent years have seen an increasing interest in laccase enzymes. Due to their ability of oxidizing various substrates, they are nowadays applied in multiple industrial fields including pulp delignification, textile dye bleaching, and bioremediation..

High relevance

Enoki · 2019 · Research Article · Molecules (Basel, Switzerland)

Characterization, Antioxidant, Anti-Aging and Organ Protective Effects of Sulfated Polysaccharides from Flammulina velutipes.

As an irreversible and complex degenerative physiological process, the treatment for aging seems strategically necessary, and polysaccharides play important roles against aging owing to their abundant bioactivities..

Immune supportSkin & hydration

High relevance

Snow Fungus · 2019 · Journal Article · International journal of medicinal mushrooms

Chemical Compounds and Antioxidant Activity of Volatile Oil from the White Jelly Mushroom, Tremella fuciformis (Tremellomycetes).

To fully analyze the composition of volatile oil extracted from Tremella fuciformis, hydrodistillation (HD) and solid phase microextraction (SPME) were adopted simultaneously..

High relevance

Enoki · 2019 · Research Article · BMC genomics

Combining transcriptomics and metabolomics to reveal the underlying molecular mechanism of ergosterol biosynthesis during the fruiting process of Flammulina velutipes.

BACKGROUND: Flammulina velutipes has been recognized as a useful basidiomycete with nutritional and medicinal values. Ergosterol, one of the main sterols of F.

Oncology

High relevance

Cordyceps · 2019 · Research Article · Insects

Comparative Transcriptome Analysis of Thitarodes Armoricanus in Response to the Entomopathogenic Fungi Paecilomyces Hepiali and Ophiocordyceps Sinensis.

Thitarodes armoricanus is a medicinal and economically important Lepidopteran insect species. The larvae infected by Paecilomyces hepiali survive no more than four days, while those infected by Ophiocordyceps sinensis can survive for several months before mummification..

Immune supportCognition & nerves

High relevance

Snow Fungus · 2019 · Journal Article · Antonie van Leeuwenhoek

Comparative transcriptomic analysis identified differentially expressed genes and pathways involved in the interaction between Tremella fuciformis and Annulohypoxylon stygium.

Tremella fuciformis is an edible and medicinal white jelly mushroom. It has a life cycle that interacts with its companion fungus Annulohypoxylon stygium, both in natural conditions and artificial cultivation.

High relevance

Cordyceps · 2019 · Journal Article · International journal of biological macromolecules

Complete mitochondrial genome of two Thitarodes species (Lepidoptera, Hepialidae), the host moths of Ophiocordyceps sinensis and phylogenetic implications.

Thitarodes (Lepidoptera, Hepialidae) is the only genus that hosts to the Ophiocordyceps sinensis, a traditional Chinese medicine considered as a powerful medicinal supplement. In this study, the complete mitochondrial genomes (mitogenomes) of two species, T.

Energy & fatigue

High relevance

Shiitake · 2019 · Research Article · Breeding science

Construction of a genetic linkage map of Lentinula edodes based on SSR, SRAP and TRAP markers.

Genetic mapping is a basic tool for eukaryotic genomic research. It allows the localization of genes or quantitative trait loci (QTLs) and map-based cloning.

High relevance

Turkey Tail · 2019 · Journal Article · Chemosphere

Cu2+-assisted laccase from Trametes versicolor enhanced self-polyreaction of triclosan.

Laccase-mediated humification processes (L-MHPs) can be used to polymerize and transform phenolic pollutants in water. However, the mechanism on Cu2+ impacts the self-polymerization of multi-purpose antimicrobial agent triclosan during L-MHPs is less understood..

Energy & fatigue

High relevance

Enoki · 2019 · Research Article · Food technology and biotechnology

Development of a Transgenic Flammulina velutipes Oral Vaccine for Hepatitis B.

Orally administered fungal vaccines show promise for the prevention of infectious diseases. Edible mushrooms are deemed appropriate hosts to produce oral vaccines due to their low production cost and low risk of gene contamination..

Immune supportLiver supportRespiratory