MycoData

BACKGROUND: Medicinal mushrooms contain biologically active substances that can be used as an immune‐modulating agent in poultry. The present study aimed to investigate the effects of Flammulina velutipes mushroom waste (FVW) on performance, immune response and serum immunity in growing layer hens..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Enoki · 2019 · Journal Article · Journal of the science of food and agriculture

Dietary inclusion of mushroom (Flammulina velutipes) stem waste on growth performance and immune responses in growing layer hens.

BACKGROUND: Medicinal mushrooms contain biologically active substances that can be used as an immune-modulating agent in poultry. The present study aimed to investigate the effects of Flammulina velutipes mushroom waste (FVW) on performance, immune response and serum immunity in growing layer hens..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Enoki · 2019 · Research Article · Animals: an open access journal from MDPI

Dietary Inclusion of Mushroom (Flammulina velutipes) Stem Waste on Growth Performance, Antibody Response, Immune Status, and Serum Cholesterol in Broiler Chickens.

This study was carried out to investigate the effects of mushroom (Flammulina velutipes) stem waste (MW) on growth performance, antibody response, immune status, and serum cholesterol in broiler chickens..

Immune supportEnergy & fatigueMetabolic health

High relevance

Turkey Tail · 2019 · Research Article · Mycobiology

Effect of Acaromyces Ingoldii Secondary Metabolites on the Growth of Brown-Rot (Gloeophyllum Trabeum) and White-Rot (Trametes Versicolor) Fungi.

We investigated the antifungal activities of an endophytic fungus identified as Acaromyces ingoldii, found on a loblolly (Pinus taeda L.) pine bolt in Louisiana during routine laboratory microbial isolations. The specific objectives were to determine the inhibitory properties of A..

High relevance

Lion's Mane · 2019 · Journal Article · Molecular medicine reports

Effect of ethanol extracts of Hericium erinaceus mycelium on morphine‑induced microglial migration.

Microglia serve important roles in chronic pain signal transduction pathways. Glia cells, especially microglia, seem to share mechanisms that lead to chronic pain and morphine‑induced tolerance..

High relevance

Enoki · 2019 · Journal Article · Meat science

Effect of Flammulina velutipes on the physicochemical and sensory characteristics of Cantonese sausages.

The effects of fresh and dried Flammulina velutipes (FFV and DFV) on quality and sensory characteristics of Cantonese sausages were investigated. Sausage samples were prepared by adding 0% (control), 2.5% FFV, 2.5% and 5.0% DFV, respectively, and their nutritional compositions, free amino acid profiles, lipid and….

High relevance

Shiitake · 2019 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Effect of heat treatments of Lentinula edodes mushroom on eritadenine concentration

High cholesterol levels in blood are a risky factor on the human health. Lentinula edodes mushroom produce the 2(R), 3(R)-dihydroxy-4-(9-adenil)-butyric acid, eritadenine.

Metabolic health

High relevance

Turkey Tail · 2019 · Research Article · ACS omega

Effect of Template Type on the Trametes versicolor Laccase-Catalyzed Oligomerization of the Aniline Dimer p-Aminodiphenylamine (PADPA).

Many previous studies have shown that (i) the oxidation of aniline or the aniline dimer p-aminodiphenylamine (PADPA) in a slightly acidic aqueous solution can be catalyzed with heme peroxidases or multicopper laccases and that (ii) subsequent reactions lead to oligomeric or polymeric products, which resemble….

Energy & fatigue

High relevance

Lion's Mane · 2019 · Research Article · Molecules (Basel, Switzerland)

Effects of Atmospheric and Room Temperature Plasma (ARTP) Mutagenesis on Physicochemical Characteristics and Immune Activity In Vitro of Hericium erinaceus Polysaccharides.

The polysaccharide is the main active substance contained in Hericium erinaceus and is commonly used in the treatment of neurasthenia, tumors, and digestive diseases. Six intracellular polysaccharide components were obtained from H..

OncologyImmune supportGut & microbiome

High relevance

Nameko · 2019 · Research Article · RSC advances

Effects of corn stalk cultivation substrate on the growth of the slippery mushroom (Pholiota microspora).

Corn stalks are a major source of agricultural waste in China that have the potential for more efficient utilisation. In this study, we designed substrate formulas with different proportions of corn stalks to cultivate Pholiota microspora.

High relevance

Enoki · 2019 · Journal Article · International journal of biological macromolecules

Effects of ultrasound-assisted extraction on antioxidant activity and bidirectional immunomodulatory activity of Flammulina velutipes polysaccharide.

In order to investigate the impacts of ultrasound-assisted extraction (UAE) on Flammulina velutipes polysaccharides (FVPs), the differences between FVPs extracted by ultrasound-assisted extraction (FVPU) and FVPs extracted by hot water extraction (FVPH) were compared in terms of yield, primary compositions, surface….

Immune support

High relevance

Snow Fungus · 2019 · Journal Article · International journal of medicinal mushrooms

Efficient Transformation of the White Jelly Mushroom Tremella fuciformis (Tremellomycetes) and Its Companion Fungus Annulohypoxylon stygium (Ascomycetes) Mediated by Agrobacterium tumefaciens.

Tremella fuciformis is an edible white jelly mushroom with medicinal qualities. The formation of T.

High relevance

Niu-Chang-Chih · 2019 · Journal Article · Applied microbiology and biotechnology

Enhancement of antroquinonol and antrodin C productions via in situ extractive fermentation of Antrodia camphorata S-29.

This study describes the application of in situ extractive fermentation (ISEF) to increase the yields of antroquinonol (AQ) and antrodin C (AC) from Antrodia camphorata S-29. In initial screening experiments, nine solvents were tested to identify the most suitable extractant for the in situ extraction of AQ and AC..

High relevance

Turkey Tail · 2019 · Journal Article · Journal of cosmetic dermatology

Enzymatic hydrolysates obtained from Trametes versicolor polysaccharopeptides protect human skin keratinocyte against AAPH-induced oxidative stress and inflammatory.

BACKGROUND: Polysaccharopeptides (PSPs) extracted from Trametes versicolor show antitumor, anti-inflammatory, and immunomodulation effects. According to our previous report, the enzymatic hydrolysates obtained from T versicolor PSPs by 80 U/mL β-1,3-D-glucanase (PSPs-EH80) did not change the functional groups of PSPs….

OncologyImmune supportEnergy & fatigueSkin & hydration

High relevance

Niu-Chang-Chih · 2019 · Journal Article · Food & function

Ergostatrien-7,9(11),22-trien-3β-ol from Antrodia camphorata ameliorates ischemic stroke brain injury via downregulation of p65NF-κ-B and caspase 3, and activation of Akt/GSK3/catenin-associated neurogenesis.

Antrodia camphorata is a well-known traditional Chinese mushroom used as a functional food and nutraceutical in Taiwan and China. The aim of this study was to explore the protective effects and mechanism(s) of the ethyl acetate crude extract of A..

Immune supportCognition & nerves

High relevance

Lion's Mane · 2019 · Journal Article · Journal of agricultural and food chemistry

Erinachromanes A and B and Erinaphenol A from the Culture Broth of Hericium erinaceus.

Three novel compounds, erinachromanes A and B (1, 2) and erinaphenol A (3), along with eight known compounds (4-11), were isolated from the culture broth of Hericium erinaceus. The structures of 1-3 were determined by the interpretation of spectroscopic data..

High relevance

Lion's Mane · 2019 · Research Article · PloS one

Erinacine A-enriched Hericium erinaceus mycelia promotes longevity in Drosophila melanogaster and aged mice.

Erinacine A-enriched Hericium erinaceus mycelia is a well-established potential therapeutic agent for neurodegenerative disorders. However, the effect of erinacine A-enriched H.

Cognition & nerves

High relevance

Shiitake · 2019 · Journal Article · International journal of biological macromolecules

Expression of a recombinant Lentinula edodes cellobiohydrolase by Pichia pastoris and its effects on in vitro ruminal fermentation of agricultural straws.

An experiment was conducted to determine the effects of recombinant cellobiohydrolase on the hydrolysis and in vitro rumen microbial fermentation of agricultural straws including rice straw, wheat straw, and corn straw. The cellobiohydrolase from Lentinula edodes (LeCel7A) was produced in Pichia pastoris..

Gut & microbiome

High relevance

Maitake · 2019 · Journal Article · Mycoscience

Expression of tyrosinase genes associated with fruiting body formation and pigmentation in Grifola frondosa

Chemical and physical properties (including ultraviolet spectrum) of a brown pigment isolated from Grifola frondosa fruiting bodies were almost identical to those of fungal melanin. From the full genome sequence of G..

Immune supportSkin & hydration

High relevance

Turkey Tail · 2019 · Journal Article · Colloids and surfaces. B, Biointerfaces

Facile immobilization of Trametes versicolor laccase on highly monodisperse superparamagnetic iron oxide nanoparticles.

HYPOTHESIS: The development of enzymatic conjugates with industrial applications require approaches with good scalability and batch-to-batch reproducibility. Hereof, nearly monodisperse iron oxide nanoparticles can be synthesized by thermal decomposition with high yields..

High relevance

Enoki · 2019 · Journal Article · Plant disease

First Report of Cedecea neteri Causing Yellow Sticky Disease in Flammulina velutipes in China

Flammulina velutipes is one of the most popular and widely cultivated edible mushrooms in many areas of China. In the summer of 2017, a yellow sticky mass was observed on the surface of stipes and pileus of F.

Gut & microbiome

High relevance

Maitake · 2019 · Journal Article · Journal of agricultural and food chemistry

Functions of a Glucan Synthase Gene GFGLS in Mycelial Growth and Polysaccharide Production of Grifola frondosa.

Glucan synthase (GLS) gene is known to be involved in the fungal biosynthesis of cell wall, differentiation, and growth. In the present study, a glucan synthase gene (GFGLS) in the edible mushroom Grifola frondosa with a full sequence of 5927 bp encoding a total of 1781 amino acids was cloned and characterized for the….

Immune support

High relevance

Shiitake · 2019 · Research Article · International journal of molecular sciences

GC⁻MS-Based Nontargeted and Targeted Metabolic Profiling Identifies Changes in the Lentinula edodes Mycelial Metabolome under High-Temperature Stress.

To clarify the physiological mechanism of the Lentinula edodes (L. edodes) response to high-temperature stress, two strains of L.

Energy & fatigueMetabolic health

High relevance

Maitake · 2019 · Journal Article · Journal of wood science

Genetic analyses of causal genes of albinism (white fruiting body) in Grifola frondosa

The tyrosinase 2 gene (tyr2) from two compatible strains of Grifola frondosa, the albino-type monokaryon strain IM-WM1-25 and the wild-type monokaryon strain IM-BM11-P21, were amplified and characterized (designated tyr2⁻Δ²⁵ and tyr2⁺, respectively)..

High relevance

Shiitake · 2019 · Research Article · Mycobiology

Genetically Independent Tetranucleotide to Hexanucleotide Core Motif SSR Markers for Identifying Lentinula edodes Cultivars.

For the purpose of protecting the rights of Lentinula edodes breeders, we developed a new simple sequence repeat (SSR) marker set consisting only of genetically independent tetranucleotide or longer core motifs. Using available genome sequences for five L..

High relevance

Zhu Ling · 2019 · Research Article · Nutrients

GPP (Composition of Ganoderma Lucidum Poly-saccharides and Polyporus Umbellatus Poly-saccharides) Enhances Innate Immune Function in Mice.

Modern research has found that Ganoderma lucidum polysaccharides (GLP) and Polyporus umbellatus polysaccharides (PUP) mainly exhibit immunoregulation. However, the immune function of a polysaccharide composition consisting of GLP and PUP has not been studied..

OncologyImmune supportMetabolic health

High relevance

Lion's Mane · 2019 · Journal Article · International journal of biological macromolecules

Green magnetic hydrogels synthesis, characterization and flavourzyme immobilization based on chitin from Hericium erinaceus residue and polyvinyl alcohol.

In this study, a novel magnetic sensitive hydrogel was prepared based on fungal chitin extracted from Hericium erinaceus residue and polyvinyl alcohol (PVA) through a green and facile procedure of repeated freezing-thaw and in situ decoration of Fe3O4..

High relevance

Turkey Tail · 2019 · Research Article · Engineering in life sciences

Green synthesis of conductive polyaniline by Trametes versicolor laccase using a DNA template.

The green synthesis of highly conductive polyaniline by using two biological macromolecules, i.e laccase as biocatalyst, and DNA as template/dopant, was achieved in this work..

High relevance

Maitake · 2019 · Journal Article · Bioscience, biotechnology, and biochemistry

Grifola frondosa extract and ergosterol reduce allergic reactions in an allergy mouse model by suppressing the degranulation of mast cells.

The increasing number of patients suffering from allergic diseases is a global health problem. Grifola frondosa is an edible mushroom consumed as a health food in Asia, and has recently been reported to have anti-allergic effects.

Immune support

High relevance

Maitake · 2019 · Journal Article · Food & function

Grifola frondosa polysaccharides ameliorate lipid metabolic disorders and gut microbiota dysbiosis in high-fat diet fed rats.

The purpose of this study was to assess the potential effects of polysaccharides from edible mushroom Grifola frondosa (GFP) on lipid metabolic disorders and gut microbiota dysbiosis, and elucidate their possible regulatory mechanisms on lipid and cholesterol metabolism in high-fat diet (HFD)-exacerbated….

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Oyster Mushroom · 2019 · Research Article · Materials (Basel, Switzerland)

Growth of Pleurotus Ostreatus on Different Textile Materials for Vertical Farming.

The mycelium of the edible mushroom Pleurotus ostreatus can be used for diverse technical applications, such as packaging materials or wastewater treatment, besides the more obvious use for nutrition. While P..

High relevance

Yellow Morel · 2019 · Research Article · Oxidative medicine and cellular longevity

Hepatoprotective Effects of Morchella esculenta against Alcohol-Induced Acute Liver Injury in the C57BL/6 Mouse Related to Nrf-2 and NF-κB Signaling.

This study investigated the hepatoprotective effects of Morchella esculenta fruit body (ME) and the underlying mechanisms in mice with alcohol-induced acute liver injury. Systematic analysis revealed that ME contained 21 types of fatty acid, 17 types of amino acid, and 12 types of mineral..

Immune supportEnergy & fatigueMetabolic healthLiver support

High relevance

Lion's Mane · 2019 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Hericium erinaceus Improves Mood and Sleep Disorders in Patients Affected by Overweight or Obesity: Could Circulating Pro-BDNF and BDNF Be Potential Biomarkers?

Epidemiological data indicate that subjects affected by obesity have an increased risk of developing mood disorders. The relationship between obesity and mood disorders is bidirectional..

Immune supportCognition & nerves

High relevance

Lion's Mane · 2019 · Research Article · Nutrients

Hericium erinaceus Improves Recognition Memory and Induces Hippocampal and Cerebellar Neurogenesis in Frail Mice during Aging.

Frailty is a geriatric syndrome associated with both locomotor and cognitive decline, implicated in both poor quality of life and negative health outcomes. One central question surrounding frailty is whether phenotypic frailty is associated with the cognitive impairment during aging..

Immune supportCognition & nervesEnergy & fatigue

High relevance

Enoki · 2019 · Research Article · Mycobiology

Identification and Characterization of Two New S-Adenosylmethionine-Dependent Methyltransferase Encoding Genes Suggested Their Involvement in Stipe Elongation of Flammulina velutipes.

Two new SAM-dependent methyltransferase encoding genes (fvsmt1 and fvsmt2) were identified from the genome of Flammulina velutipes. In order to make a comprehensive characterization of both genes, we performed in silico analysis of both genes and used qRT-PCR to reveal their expression patterns during the development….

Energy & fatigue

High relevance

Shiitake · 2019 · Research Article · Molecules (Basel, Switzerland)

Identification of a Heat-Inducible Element of Cysteine Desulfurase Gene Promoter in Lentinula edodes.

Volatile organosulfur compounds are the main components that contribute to the unique aroma of dried Lentinula edodes. They are mainly generated during the hot-air drying process, and cysteine desulfurase is the key enzyme in this process..

High relevance

Cordyceps · 2019 · Journal Article · Science China. Life sciences

Identification of microRNA-like RNAs in Ophiocordyceps sinensis.

Ophiocordyceps sinensis is well known as a traditional Chinese medicine and has widely been used for over 2,000 years to stimulate immune system, decrease blood pressure and to inhibit tumor growth..

OncologyImmune supportMetabolic health

High relevance

Turkey Tail · 2019 · Research Article · International journal of medical sciences

In Vitro Anti-proliferative and Anti-invasive Effect of Polysaccharide-rich Extracts from Trametes Versicolor and Grifola Frondosa in Colon Cancer Cells.

Colorectal cancer (CRC) is one of leading causes of mortality in western countries and novel treatment strategies are required. The medicinal application of mushrooms has been used in traditional medicine in many oriental countries..

OncologyImmune supportGut & microbiomeSkin & hydration

High relevance

Chaga · 2019 · Journal Article · International journal of biological macromolecules

Inonotus obliquus polysaccharides protect against Alzheimer's disease by regulating Nrf2 signaling and exerting antioxidative and antiapoptotic effects.

Inonotus obliquus polysaccharide (IOPS) was initially separated and purified via precipitation from an aqueous extract with 80% alcohol, a DEAE-52 cellulose anion exchange column, and a Sephadex G-100 gel permeation chromatography system. IOPS was found to have a molecular weight of 111.9 kDa..

OncologyImmune supportCognition & nervesEnergy & fatigue

High relevance

Lion's Mane · 2019 · Journal Article · Food Hydrocolloids

Isolation of crude oligosaccharides from Hericium erinaceus by integrated membrane technology and its proliferative activity

In this study, isolation of crude oligosaccharides from Hericium erinaceus (CHOS), and its physicochemical properties and proliferative effects on lactic acid bacteria were investigated..

Immune supportGut & microbiome

High relevance

Shiitake · 2019 · Research Article · Frontiers in microbiology

Lentinula edodes Mycelium as Effective Agent for Piroxicam Mycoremediation.

Pollution of the environment with inorganic and organic substances is one of the main problems in the world. For this reason, it is necessary to conduct researches for effective methods of biodegradation of xenobiotics, including drugs whose unmetabolized forms are introduced into the environment, especially into….

OncologyImmune supportMetabolic health

High relevance

Lion's Mane · 2019 · Journal Article · Carbohydrate polymers

Magnetic chitin hydrogels prepared from Hericium erinaceus residues with tunable characteristics: A novel biosorbent for Cu2+ removal.

Development of sustainable biomaterials from wasted resources has been widely advocated recently. In this study, chitin was extracted from Hericium erinaceus residues and used as the main framework to in situ synthesize series of magnetic chitin hydrogels for Cu2+ removal..

Energy & fatigue

High relevance

Lion's Mane · 2019 · Journal Article · Carbohydrate polymers

Magnetic sensitive Hericium erinaceus residue chitin/Cu hydrogel nanocomposites for H2 generation by catalyzing NaBH4 hydrolysis

In this study, a novel magnetic Hericium erinaceus residue chitin hydrogel was prepared and applied as template for in-situ synthesis of Cu nanoparticles, the prepared magnetic chitin/Cu hydrogel nanocomposites were further utilized as catalyst for H2 generation from NaBH4 hydrolysis..

High relevance

Oyster Mushroom · 2019 · Research Article · Frontiers in microbiology

Metabolic Response of Pleurotus ostreatus to Continuous Heat Stress.

Heat stress seriously threatens the growth of Pleurotus ostreatus. Various studies have been performed to study the resistance of P.

Metabolic health

High relevance

Maitake · 2019 · Journal Article · Mycoscience

Mitochondrial DNA dynamics during fruiting body formation in Grifola frondosa

In the present study, the copy number of mitochondrial DNA in Grifola frondosa was estimated at several developmental stages by quantitative real-time PCR, revealing that it decreases gradually during fruiting body development..

Energy & fatigueRespiratory

High relevance

Shiitake · 2019 · Research Article · 3 Biotech

Mycoremediation of azole antifungal agents using in vitro cultures of Lentinula edodes.

Azole antifungal agents are widely used as active ingredients in antifungal pharmaceuticals and agricultural fungicides. An increase in the use of azole antifungals has resulted in an increase in the concentration of these compounds in wastewater and surface water, with potential implications for agriculture..

High relevance

Shiitake · 2019 · Journal Article · Journal of bioscience and bioengineering

Overexpression and repression of the tyrosinase gene in Lentinula edodes using the pChG vector.

Tyrosinase is an industrially useful enzyme, however, it causes gill browning of Lentinula edodes fruiting bodies during preservation. In this study, we constructed two vectors, pChG-gTs and pChG-gTa, expressing sense and antisense tyrosinase gene of L..

High relevance

Shiitake · 2019 · Journal Article · Mycoscience

Overexpression of the laccase gene, lcc1, in Lentinula edodes using the pChG vector

Lentinula edodes secretes laccase (Lcc: EC 1.10.3.2), an industrially useful enzyme. In this study, we introduced and expressed the L.

High relevance

Enoki · 2019 · Journal Article · Journal of basic microbiology

Overexpression of the saccharopine dehydrogenase gene improves lysine biosynthesis in Flammulina velutipes.

Saccharopine dehydrogenase (EC 1.5.1.7) regulates the last step of fungal lysine biosynthesis. The gene (Fvsdh) encoding saccharopine dehydrogenase was identified and cloned from the whole genome of Flammulina velutipes.

High relevance

Mesima · 2019 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Phellinus linteus Grown on Germinated Brown Rice Inhibits IgE-Mediated Allergic Activity through the Suppression of FcεRI-Dependent Signaling Pathway In Vitro and In Vivo.

Phellinus linteus (PL) has been used as a traditional herbal medicine owing to its immune regulatory activity. Previous studies reported that PL grown on germinated brown rice (PBR) exerted immunomodulatory, anticancer, and anti-inflammatory activities..

OncologyImmune support