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Medicinal fungi research database
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Oyster Mushroom
Pleurotus ostreatus
- Studies
- 1,947
- Avg relevance
- 53
- Latest
- 2026
Species record
Reishi · Lingzhi
Ganoderma lucidum
- Studies
- 1,830
- Avg relevance
- 60
- Latest
- 2026
Species record
Turkey Tail · Yun Zhi
Trametes versicolor
- Studies
- 1,828
- Avg relevance
- 41
- Latest
- 2026
Species record
Shiitake · Hua Gu
Lentinula edodes
- Studies
- 1,766
- Avg relevance
- 60
- Latest
- 2026
Species record
Cordyceps · Scarlet Club
Cordyceps militaris
- Studies
- 1,635
- Avg relevance
- 67
- Latest
- 2026
Species record
Cordyceps · Caterpillar Fungus
Ophiocordyceps sinensis
- Studies
- 1,576
- Avg relevance
- 59
- Latest
- 2026
Species record
Almond Mushroom · ABM
Agaricus blazei
- Studies
- 1,441
- Avg relevance
- 54
- Latest
- 2026
Species record
Enoki · Winter Mushroom
Flammulina velutipes
- Studies
- 1,403
- Avg relevance
- 47
- Latest
- 2026
Species record
King Oyster · Eryngii
Pleurotus eryngii
- Studies
- 1,278
- Avg relevance
- 60
- Latest
- 2026
Species record
Maitake · Hen of the Woods
Grifola frondosa
- Studies
- 1,276
- Avg relevance
- 48
- Latest
- 2026
Species record
Snow Fungus · Silver Ear
Tremella fuciformis
- Studies
- 1,052
- Avg relevance
- 29
- Latest
- 2026
Species record
Lion's Mane · Yamabushitake
Hericium erinaceus
- Studies
- 862
- Avg relevance
- 67
- Latest
- 2026
Species record
Chaga
Inonotus obliquus
- Studies
- 738
- Avg relevance
- 65
- Latest
- 2026
Species record
Mesima · Sanghwang
Phellinus linteus
- Studies
- 722
- Avg relevance
- 58
- Latest
- 2026
Species record
Niu-Chang-Chih
Antrodia camphorata
- Studies
- 496
- Avg relevance
- 63
- Latest
- 2026
Species record
Nameko · Nametake
Pholiota microspora
- Studies
- 421
- Avg relevance
- 29
- Latest
- 2026
Species record
Yellow Morel
Morchella esculenta
- Studies
- 392
- Avg relevance
- 42
- Latest
- 2026
Species record
Zhu Ling · Umbrella Polypore
Polyporus umbellatus
- Studies
- 263
- Avg relevance
- 55
- Latest
- 2026
Species record
Wood Ear · Kikurage
Auricularia auricula-judae
- Studies
- 254
- Avg relevance
- 51
- Latest
- 2026
Species record
Agarikon · Quinine Conk
Fomitopsis officinalis
- Studies
- 47
- Avg relevance
- 55
- Latest
- 2026
Articles
17,669 results
Showing 4,751–4,800 of 17,669
Lion's Mane · 2019 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire
Physicochemical, structural and rheological properties of alkali-extracted polysaccharide from fruiting body of Hericium erinaceus
An alkali-extracted polysaccharide (HEAEP-0.5) was prepared from the water insoluble residue of Hericium erinaceus fruiting body. Effects of concentration, temperature, pH and salts on its rheological property were systematically evaluated..
Turkey Tail · 2019 · Journal Article · International journal of biological macromolecules
Polysaccharopeptide from Trametes versicolor blocks inflammatory osteoarthritis pain-morphine tolerance effects via activating cannabinoid type 2 receptor.
Analgesia with opioids such as morphine is an effective clinical strategy for the treatment of cancer pain and chronic inflammatory pain. However, long-term use of morphine can cause morphine tolerance (MT), which limits the clinical application of opioids..
Zhu Ling · 2019 · Journal Article · The Science of the total environment
Predicting the impacts of climate change, soils and vegetation types on the geographic distribution of Polyporus umbellatus in China.
Polyporus umbellatus is a fungus that has been used medically as a diuretic for thousands of years in China. To evaluate the impacts of climatic change on the distribution of P..
Enoki · 2019 · Journal Article · International journal of biological macromolecules
Preparation and in vitro absorption studies of a novel polysaccharide‑iron (III) complex from Flammulina velutipes.
Iron is essential in fundamental bioactivities, so it makes sense to improve the efficiency of iron on epithelial transport. In this work, a novel polysaccharide‑iron(III) complex (FVP-Fe(III)) was prepared from Flammulina velutipes with a specific structure..
Enoki · 2019 · Journal Article · Journal of food processing and preservation
Properties of soy protein isolate/nano‐silica films and their applications in the preservation of Flammulina velutipes
This work evaluated the properties of soy protein isolate (SPI)/nano‐silica (nano‐SiO₂) films. The particle size distribution of the film solutions and the Fourier‐transform infrared spectroscopy, X‐ray diffraction, and X‐ray photoelectron spectroscopy of films indicated that there were hydrogen bonds and coordinate….
Shiitake · 2019 · Journal Article · Journal of agricultural and food chemistry
Purification and Characterization of a Cadmium-Binding Protein from Lentinula edodes.
Many organisms possess the ability to produce metal-binding proteins to absorb cadmium. Metallothioneins, an important family of cysteine-rich metal-binding proteins, have been isolated and well characterized..
Shiitake · 2019 · Journal Article · Journal of agricultural and food chemistry
Remediation and Mechanisms of Cadmium Biosorption by a Cadmium-Binding Protein from Lentinula edodes.
Cadmium bioremediation with metal-binding proteins is primarily conducted using metallothioneins (MTs). However, in the present study, we investigated a non-MT cadmium-binding protein from Lentinula edodes (LECBP) as a remediation tool for cadmium biosorption in Escherichia coli..
Zhu Ling · 2019 · Journal Article · Carbohydrate polymers
Renoprotective effect and mechanism of polysaccharide from Polyporus umbellatus sclerotia on renal fibrosis
As a fungal polysaccharide, polysaccharide (PPUS) from Polyporus umbellatus sclerotia have showed remarkable anti-inflammatory activities. In view of the closely relationship between inflammation and renal fibrosis, and considering the significant role of other fungal polysaccharides in treatment renal fibrosis, we….
Zhu Ling · 2019 · Journal Article · Carbohydrate polymers
Renoprotective effect and mechanism of polysaccharide from Polyporus umbellatus sclerotia on renal fibrosis.
As a fungal polysaccharide, polysaccharide (PPUS) from Polyporus umbellatus sclerotia have showed remarkable anti-inflammatory activities. In view of the closely relationship between inflammation and renal fibrosis, and considering the significant role of other fungal polysaccharides on treatment of renal fibrosis, we….
Shiitake · 2019 · Journal Article · Meat science
Roles of Lentinula edodes as the pork lean meat replacer in production of the sausage.
The effects of substituting pork lean meat with Lentinula edodes (LE) on the physicochemical properties, amino acid content, cooking loss, texture, total phenolic content, antioxidant activity, microstructure, microbiological analysis, and sensory characteristics of sausages were evaluated..
Niu-Chang-Chih · 2019 · Journal Article · Chinese journal of natural medicines
Secondary metabolites of petri-dish cultured Antrodia camphorata and their hepatoprotective activities against alcohol-induced liver injury in mice.
Antrodia camphorata, a well-known and highly valued edible medicinal mushroom with intriguing activities like liver protection, has been traditionally used for the treatment of alcoholic liver disease. A.
Turkey Tail · 2019 · Research Article · 3 Biotech
Simultaneous laccase production and transformation of bisphenol-A and triclosan using Trametes versicolor.
New age micro-pollutants, bisphenol-A (BPA) and triclosan (TCA), known for their carcinogenic effects in living organisms can effectively be removed from water using laccase from Trametes versicolor. Laccase was produced from T.
Chaga · 2019 · Research Article · Molecules (Basel, Switzerland)
Simultaneous Use of Stimulatory Agents to Enhance the Production and Hypoglycaemic Activity of Polysaccharides from Inonotus obliquus by Submerged Fermentation.
This study aimed to determine the effect of applying stimulatory agents to liquid cultured Inonotus obliquus on the simultaneous accumulation of exo-polysaccharides (EPS) and their monosaccharide composition..
Snow Fungus · 2019 · Journal Article · Food Hydrocolloids
Stability, microstructure, and digestibility of whey protein isolate – Tremella fuciformis polysaccharide complexes
Manufacturing of protein-enriched beverages is an interesting field which has attracted a lot of attention from the research community. In this study, polysaccharides extracted from a mushroom (Tremella fuciformis) were used to enhance the stability of 5% whey protein isolate (WPI) solution for enriched beverage….
Niu-Chang-Chih · 2019 · Research Article · RSC advances
Structural characterization and anti-inflammatory effect in hepatocytes of a galactoglucan from Antrodia camphorata mycelium.
The galactoglucan ACP2 was isolated from cultured Antrodia camphorata mycelium through anion-exchange column chromatography and Sephadex G-100 chromatography and shown to exhibit hepatoprotective function in L02 cells..
Maitake · 2019 · Research Article · BioMed research international
Structural Elucidation and Immune-Enhancing Effects of Novel Polysaccharide from Grifola frondosa.
Beta-glucan (β-glucan) is a macromolecule structure where glucose unit has bonded through β-glycosidic bond at 1 and 3 positions. It is well known as a natural immunomodulator without exhibiting any side effects via enhancing immunity..
Lion's Mane · 2019 · Journal Article · Carbohydrate polymers
Structural elucidation and immunomodulatory activity of a β-D-glucan prepared by freeze-thawing from Hericium erinaceus
H6PC20, a water-soluble β-D-glucan, with a molecular mass of 2390 kDa (HPSEC-MALLS-RI), was obtained by extracting the fresh fruiting bodies of Hericium erinaceus at mature stage with hot water, freeze-thawing, precipitating and further rinsing with 20% (v/v) of ethanol..
Lion's Mane · 2019 · Journal Article · Carbohydrate polymers
Structural elucidation and immunomodulatory activity of a β-D-glucan prepared by freeze-thawing from Hericium erinaceus.
H6PC20, a water-soluble β-D-glucan, with a molecular mass of 2390 kDa (HPSEC-MALLS-RI), was obtained by extracting the fresh fruiting bodies of Hericium erinaceus at mature stage with hot water, freeze-thawing, precipitating and further rinsing with 20% (v/v) of ethanol..
Shiitake · 2019 · Journal Article · Food Hydrocolloids
Structure, thermal and rheological properties of different soluble dietary fiber fractions from mushroom Lentinula edodes (Berk.) Pegler residues
Four soluble dietary fiber subfractions were obtained via stepwise ethanol precipitation from Lentinula edodes by-products (LESDF). The molecular weight distributions of these four LESDF subfractions were 6.43 × 107 Da, 6.25 × 106 Da, 1.58 × 105 Da and 2.50 × 104 Da, respectively, and they exhibited different surface….
Turkey Tail · 2019 · Journal Article · Chemosphere
Study on transformation and degradation of bisphenol A by Trametes versicolor laccase and simulation of molecular docking.
As a typical class of environmental endocrine disruptors, bisphenol A poses a potential threat to the sustainable survival and reproduction of living beings and human beings..
Niu-Chang-Chih · 2019 · Research Article · Molecules (Basel, Switzerland)
The Effects of Ergosta-7,9(11),22-trien-3β-ol from Antrodia camphorata on the Biochemical Profile and Exercise Performance of Mice.
Antrodia camphorata (AC) is a rare and unique mushroom that is difficult to cultivate. Previous studies have demonstrated the bioactivity of the compound Ergosta-7,9(11),22-trien-3β-ol (EK100) from AC in submerged culture..
Enoki · 2019 · Journal Article · International journal of medicinal mushrooms
The Effects of Ethanol Concentration during Isolation and Purity on the In Vitro Antioxidant Properties of Polysaccharides from the Winter Culinary-Medicinal Mushroom, Flammulina velutipes (Agaricomycetes) Stembase.
Natural products with high antioxidant activity have attracted great attention in recent years. A water extraction and alcohol precipitation method were used to extract polysaccharides from the Flammulina velutipes stem-base (FVSP)..
Wood Ear · 2019 · Journal Article · Natural product research
The medicinal mushroom Auricularia auricula-judae (Bull.) extract has antioxidant activity and promotes procollagen biosynthesis in HaCaT cells.
In this study, Auricularia auricula-judae (Bull.) extract (AAE) had potent antioxidant activity in vitro and promoted the biosynthesis of procollagen, a precursor of collagen in HaCaT cells..
Lion's Mane · 2019 · Research Article · International journal of molecular sciences
The Neuroprotective Effect of Hericium erinaceus Extracts in Mouse Hippocampus after Pilocarpine-Induced Status Epilepticus.
Hericium erinaceus (HE), a culinary-medicinal mushroom, has shown therapeutic potential in many brain diseases. However, the role of HE in status epilepticus (SE)-mediated neuronal death and its underlying mechanisms remain unclear..
Chaga · 2019 · Journal Article · International journal of biological macromolecules
The polysaccharide from Inonotus obliquus protects mice from Toxoplasma gondii-induced liver injury.
The study aimed to explore the protective effects and mechanism of Inonotus obliquus polysaccharide (IOP) on liver injury caused by Toxoplasma gondii (T. gondii) infection in mice..
Maitake · 2019 · Research Article · International journal of molecular sciences
The Positive Effects of Grifola frondosa Heteropolysaccharide on NAFLD and Regulation of the Gut Microbiota.
: Non-alcoholic fatty liver disease (NAFLD) is a major public health problem in many countries. In this study, the ability of Grifola frondosa heteropolysaccharide (GFP) to ameliorate NAFLD was investigated in rats fed a high-fat diet (HFD)..
Chaga · 2019 · Research Article · Molecules (Basel, Switzerland)
Three-Phase Partitioning for the Extraction and Purification of Polysaccharides from the Immunomodulatory Medicinal Mushroom Inonotus obliquus.
Polysaccharides from the immunomodulatory medicinal mushroom Inonotus obliquus (IOPS) were extracted and purified using three-phase partitioning (TPP), which is an efficient, fast, safe, and green purification technique..
Enoki · 2019 · Research Article · Frontiers in microbiology
Transcriptional Changes on Blight Fruiting Body of Flammulina velutipes Caused by Two New Bacterial Pathogens.
A blight disease of Flammulina velutipes was identified with symptoms of growth cessation of young fruiting bodies, short stipe, and brown spots on the pileus. The pathogenic bacteria were identified as Arthrobacter arilaitensis and Pseudomonas yamanorum by Koch's postulate, gram staining, morphological and 16S….
Lion's Mane · 2019 · Journal Article · International journal of biological macromolecules
Transcriptome analysis of the effects of Hericium erinaceus polysaccharide on the lymphocyte homing in Muscovy duck reovirus-infected ducklings.
Hericium erinaceus polysaccharide (HEP) is a bioactive substance present in the fruiting bodies of H. erinaceus.
Turkey Tail · 2019 · Research Article · International journal of molecular sciences
Use of the Secreted Proteome of Trametes versicolor for Controlling the Cereal Pathogen Fusarium langsethiae.
Fusarium langsethiae is amongst the most recently discovered pathogens of small grains cereals. F.
Shiitake · 2019 · Research Article · Frontiers in microbiology
Variations in Nuclear Number and Size in Vegetative Hyphae of the Edible Mushroom Lentinula edodes.
In basidiomycete fungi, the number of nuclei and their ploidy level per nucleus can vary tremendously among species; however, within species, nuclear number and ploidy levels are traditionally considered fixed in their vegetative hyphae..
Turkey Tail · 2018 · Journal Article · Sheng wu gong cheng xue bao = Chinese journal of biotechnology
[Expression and characterization of NADPH-cytochrome P450 reductase from Trametes versicolor in Escherichia coli].
Trametes versicolor has strong ability to degrade environmental organic pollutants. NADPH-cytochrome P450 reductase (CPR) of T.
Mesima · 2018 · Research Article · Oncotarget
A lethal synergy induced by phellinus linteus and camptothecin11 in colon cancer cells.
Side effects of anti-cancer drugs are always challenging for effective cancer treatments. The polysaccharides extracted from Phellinus linteus (PLGL) have been widely used in treating cancers.
Maitake · 2018 · Journal Article · International journal of biological macromolecules
A novel iron supplements preparation from Grifola frondosa polysaccharide and assessment of antioxidant, lymphocyte proliferation and complement fixing activities.
Grifola frondosa polysaccharide-iron (III) complex (GFP-iron) was synthesized and characterized. Based on single factor and orthogonal optimization experiments of GFP-iron (III) complex synthesis, the optimum conditions were the reaction temperature 80°C, pH 8, reaction time 90min and ratio of catalyst to GFP….
Chaga · 2018 · Research Article · International journal of molecular sciences
Actions of Inonotus obliquus against Hyperuricemia through XOD and Bioactives Screened by Molecular Modeling.
Inonotus obliquus is an edible mushroom and also a remedy against various diseases, especially metabolic syndrome. In this paper we report the actions of an ethanol extract of I.
Shiitake · 2018 · Research Article · Mycobiology
Activation of the Mating Pheromone Response Pathway of Lentinula edodes by Synthetic Pheromones.
Pheromone (PHB)-receptor (RCB) interaction in the mating pheromone response pathway of Lentinula edodes was investigated using synthetic PHBs. Functionality of the C-terminally carboxymethylated synthetic PHBs was demonstrated by concentration-dependent induction of a mating-related gene (znf2) expression and by….
Lion's Mane · 2018 · Journal Article · Drug and chemical toxicology
Acute and developmental toxicity assessment of erincine A-enriched Hericium erinaceus mycelia in Sprague-Dawley rats.
This study aimed to establish an in vitro model to confirm the efficacy of erinacine A-enriched Hericium erinaceus (EAHE) mycelia and investigate its potential adverse effects in a preclinical experimental setting, including an assessment on the oral administration of EAHE mycelia in acute and prenatal developmental….
Almond Mushroom · 2018 · Journal Article · Nutritional neuroscience
Agaricus blazei extract abrogates rotenone-induced dopamine depletion and motor deficits by its anti-oxidative and anti-inflammatory properties in Parkinsonic mice.
Neuroinflammation and oxidative damage are the two main malfactors that play an important role in the pathogenesis of experimental and clinical Parkinson's disease (PD). The current study was aimed to study the possible anti-oxidant and anti-inflammatory effects of the methanolic extract of Agaricus blazei (A..
Almond Mushroom · 2018 · Journal Article · Nutritional neuroscience
Agaricus blazei extract attenuates rotenone-induced apoptosis through its mitochondrial protective and antioxidant properties in SH-SY5Y neuroblastoma cells.
The present study was aimed to find out the effect of Agaricus blazei mushroom extract against rotenone-induced cellular model. SH-SY5Y neuroblastoma cells are divided into four experimental groups (control, rotenone (100 nM), A.
Almond Mushroom · 2018 · Journal Article · Biological trace element research
Agaricus blazei Murill Polysaccharides Protect Against Cadmium-Induced Oxidative Stress and Inflammatory Damage in Chicken Spleens.
Agaricus blazei Murill polysaccharide (ABP) has exhibited antioxidant and immunoregulatory activity. The aim of this study was to investigate the effect of ABP on cadmium (Cd)-induced antioxidant functions and inflammatory damage in chicken spleens..
Shiitake · 2018 · Research Article · 3 Biotech
Analysis of the biodegradation of synthetic testosterone and 17α-ethynylestradiol using the edible mushroom Lentinula edodes.
The mycelium of Lentinula edodes produces enzymes which may degrade xenobiotics including steroid hormones. The aim of the study was to determine whether the mycelium from in vitro cultures of L.
Mesima · 2018 · Journal Article · Journal of microbiology and biotechnology
Anti-Pigmentation Effects of Eight Phellinus linteus-Fermented Traditional Crude Herbal Extracts on Brown Guinea Pigs of Ultraviolet B-Induced Hyperpigmentation.
We have previously found that mycelia culture broth of eight kinds of traditional herbal extracts fermented with Phellinus linteus (previously named as 8-HsPLCB) not only inhibited melanin and tyrosinase activity, but also reduced the contents of melanogenesis-related proteins, including tyrosinase and….
Niu-Chang-Chih · 2018 · Research Article · RSC advances
Antidiabetic and hypolipidemic activities of eburicoic acid, a triterpenoid compound from Antrodia camphorata, by regulation of Akt phosphorylation, gluconeogenesis, and PPARα in streptozotocin-induced diabetic mice.
The study is designed to examine the potential effects and underlying mechanisms of eburicoic acid (TRR), a compound from Antrodia camphorata, in streptozotocin (STZ)-induced diabetic mice..
Shiitake · 2018 · Journal Article · International journal of biological macromolecules
Antioxidant and anti-inflammation of enzymatic-hydrolysis residue polysaccharides by Lentinula edodes.
The present work investigated the antioxidative, anti-inflammatory and organ protective effects of residue polysaccharide (RPS) and its enzymatic-RPS (ERPS) of Lentinula edodes against the LPS-induced sepsis in mice..
Niu-Chang-Chih · 2018 · Research Article · Frontiers in pharmacology
Antrodia camphorata Mycelia Exert Anti-liver Cancer Effects and Inhibit STAT3 Signaling in vitro and in vivo.
Hepatocellular carcinoma (HCC), the major form of primary liver cancer, is a common cause of cancer-related death worldwide. Signal transducer and activator of transcription 3 (STAT3) signaling is constantly activated in HCC and has been proposed as a chemotherapeutic target for HCC..
Maitake · 2018 · Research Article · AMB Express
Assessing the effects of different agro-residue as substrates on growth cycle and yield of Grifola frondosa and statistical optimization of substrate components using simplex-lattice design.
Grifola frondosa is an economically important edible and medicinal mushroom usually produced on substrate consisting of sawdust supplemented with wheat bran. Cultivation of G..
Turkey Tail · 2018 · Journal Article · Journal of wood science
Biodegradation of diuron in artificially contaminated water and seawater by wood colonized with the white-rot fungus Trametes versicolor
We investigated the potential of white-rot fungi for bioremediation of aqueous environments contaminated with diuron (3-(3,4-dichlorophenyl)-1,1-dimethylurea). First, diuron degradation activities of several white-rot fungi (Ceriporia lacerata, Phanerochaete chrysosporium, Phanerochaete sordida, Trametes versicolor)….
Turkey Tail · 2018 · Journal Article · Environmental technology
Biosurfactant production by Trametes versicolor grown on two-phase olive mill waste in solid-state fermentation.
Biosurfactants are amphiphilic compounds of microbial origin which exhibit better properties than their chemically derived counterparts. They are usually produced in submerged fermentation by different types of bacteria..
Enoki · 2018 · Journal Article · Pakistan journal of pharmaceutical sciences
Cellulase-assisted extraction and anti-ultraviolet activity of polysaccharides from the root of Flammulina velutipes on Caenorhabditis elegans.
We investigated the cellulase-assisted extraction and anti-ultraviolet activity of water-soluble polysaccharides from the root of Flammulina velutipes on Caenorhabditis elegans..
Maitake · 2018 · Journal Article · Carbohydrate polymers
Chemical structure of a partially 3-O-methylated mannofucogalactan from edible mushroom Grifola frondosa.
An unusual heteropolysaccharide was isolated from the fruiting bodies of the medicinal mushroom Grifola frondosa, via successive cold aqueous extraction, followed by fractionation through freeze-thawing, precipitation with Fehling solution and dialysis using a membrane with a size exclusion cut-off of 500 kDa..