MycoData

A novel 57-kDa acidic α-galactosidase designated as HEG has been purified from the dry fruiting bodies of Hericium erinaceus. The isolation protocol involved ion-exchange chromatography and gel filtration on a Superdex75 column.

Immune support

High relevance

Maitake · 2018 · Journal Article · International journal of biological macromolecules

Purification and structural elucidation of a water-soluble polysaccharide from the fruiting bodies of the Grifola frondosa.

Grifola frondosa is a polypore mushroom, which has been used for many centuries by traditional Chinese and Japanese herbalists as a medicinal mushroom. A water-soluble polysaccharide (code as GFP30-2-a, molecular weight: 2.04×106Da) was isolated from the fruiting bodies of G..

Immune support

High relevance

Maitake · 2018 · Journal Article · International journal of biological macromolecules

Purification, characterization and immunomodulatory activity of a novel polysaccharide from Grifola frondosa.

A novel bioactive polysaccharide, GFP-22, was isolated from the fruit bodies of Grifola frondosa by anion-exchange and gel filtration chromatography. Structure of GFP-22 was investigated using gas chromatography-mass spectrometry (GC-MS), methylation, nuclear magnetic resonance (NMR), high-performance size exclusion….

OncologyImmune supportEnergy & fatigue

High relevance

Shiitake · 2018 · Research Article · BioMed research international

Reference Gene Selection for Quantitative Real-Time PCR of Mycelia from Lentinula edodes under High-Temperature Stress.

Housekeeping genes are important for measuring the transcription expression of functional genes; 10 traditional reference genes, TUB, TUA, GADPH, EF1, 18S, GTP, ACT, UBI, UBC, and H2A, were tested for their adequacy in Lentinula edodes (L. edodes)..

High relevance

Turkey Tail · 2018 · Journal Article · Water science and technology: a journal of the International Association on Water Pollution Research

Removal of phenols-like substances in pharmaceutical wastewater with fungal bioreactors by adding Trametes versicolor.

Fungi are known to be more resistant to toxic compounds and more effective in removing recalcitrant organics such as phenols than bacteria. Here we examined the removal of phenols (as a component of Zopliclone drugs), added to non-sterile pharmaceutical wastewater with continuous treatment fungal bioreactor by its….

High relevance

Niu-Chang-Chih · 2018 · Journal Article · Fitoterapia

Reprint of: Antiproliferative activity of the Antrodia camphorata secondary metabolite 4,7-dimethoxy-5-methylbenzo[d][1,3]dioxole and analogues.

Both the traditional Chinese medicinal fungus, Antrodia camphorata, and its secondary metabolite, 4,7-dimethoxy-5-methylbenzo[d][1,3]dioxole, have been reported to possess promising anticancer activity..

Oncology

High relevance

Shiitake · 2018 · Research Article · Molecules (Basel, Switzerland)

Selection of Reference Genes for qRT-PCR Analysis in Lentinula edodes after Hot-Air Drying.

Volatile sulfur compounds gradually develop in Lentinula edodes after hot-air drying, and many genes are involved in the generation of these sulfur compounds. The expression stability of reference genes may vary in a particular experimental treatment when analyzing their expressions by quantitative real-time….

High relevance

Shiitake · 2018 · Research Article · Molecules (Basel, Switzerland)

Site-Directed Mutagenesis of a β-Glycoside Hydrolase from Lentinula Edodes.

The β-glycoside hydrolases (LXYL-P1-1 and LXYL-P1-2) from Lentinula edodes (strain M95.33) can specifically hydrolyze 7-β-xylosyl-10-deacetyltaxol (XDT) to form 10-deacetyltaxol for the semi-synthesis of Taxol..

High relevance

Chaga · 2018 · Journal Article · Bioresource technology

Solid state bioconversion of lignocellulosic residues by Inonotus obliquus for production of cellulolytic enzymes and saccharification.

White rot fungi have been usually considered for lignin degradation and ligninolytic enzyme production. To understand whether the white rot fungus Inonotus obliquus was able to produce highly efficient cellulase system, the production of cellulolytic enzyme cocktails was optimized under solid state fermentation..

High relevance

Turkey Tail · 2018 · Journal Article · Journal of biotechnology

Statistical optimisation of enzymatic detoxification with laccase from Trametes versicolor for spent sulphite liquors using a novel in-situ NMR method.

Within this study the mediated detoxification of spent sulphite liquor via laccase from Trametes versicolor was analysed and optimised using an in-situ NMR-spectroscopy method. The enzymatic degradation kinetic was optimised using the degradation rate of aromatic compounds as indirect parameter..

High relevance

Enoki · 2018 · Journal Article · Carbohydrate polymers

Structural characteristics and bioactive properties of a novel polysaccharide from Flammulina velutipes.

A new water-soluble polysaccharide (FVP1) was extracted from Flammulina velutipes by traditional method "water extraction and alcohol precipitation" and purified by column chromatography. Physicochemical characterization showed that FVP1 was a homogeneous polysaccharide with a relative molecular weight of 54.78 kDa..

OncologyImmune supportMetabolic healthLiver support

High relevance

Maitake · 2018 · Journal Article · Carbohydrate polymers

Structural characterization and antidiabetic potential of a novel heteropolysaccharide from Grifola frondosa via IRS1/PI3K-JNK signaling pathways.

A novel heteropolysaccharide from Grifola frondosa named GFP-W has been isolated and purified by DEAE Sephadex A-52 chromatography. Gas chromatography, fourier transform infrared spectroscopy, one-dimensional (1H- and 13C-) and two-dimensional (1H-1H COSY, 1H-13C HSQC, and 1H-13C HMBC) nuclear magnetic resonance….

Immune supportMetabolic health

High relevance

Wood Ear · 2018 · Journal Article · International journal of biological macromolecules

Structural characterization and immunomodulatory activity of exopolysaccharides from submerged culture of Auricularia auricula-judae.

Submerged culture of Auricularia auricula-judae has been documented, but there have been few studies on the structural characterization and medicinal properties of its exopolysaccharides. In present study, two exopolysaccharides, named CEPSN-1 and CEPSN-2, were isolated from submerged culture of A..

Immune supportMetabolic health

High relevance

Enoki · 2018 · Journal Article · Carbohydrate polymers

Structural characterization and macrophage activation of a hetero-galactan isolated from Flammulina velutipes.

We isolated and purified a new polysaccharide (WFVP-N-b1) with a molecular weight of 20 kDa from Flammulina velutipes. Results showed that WFVP-N-b1 is composed of an α (1 → 6)-linked D-galactan backbone and branched at the O-2 of its Galp residues by an α-D-(1 → 6)-linked Manp attached to t-β-D-Glcp or t-α-D-Fucp….

Immune support

High relevance

Yellow Morel · 2018 · Journal Article · Carbohydrate polymers

Structural characterization, in vitro and in vivo antioxidant activities of a heteropolysaccharide from the fruiting bodies of Morchella esculenta.

This study aimed to investigate the structural features, in vitro and in vivo antioxidant activities of a heteropolysaccharide from the fruiting bodies of Morchella esculenta (FMP-1). FMP-1 had an average molecular weight of 4.7 × 103 Da and consisted of mannose, glucose and galactose..

Immune supportMetabolic health

High relevance

Lion's Mane · 2018 · Research Article · Polymers

Structural Properties and Macrophage Activation of Cell Wall Polysaccharides from the Fruiting Bodies of Hericium erinaceus.

In this study, water-soluble and alkali-soluble cell wall polysaccharides were obtained from fruiting body extracted residual micropowders of Hericium erinaceus, harvested at seven different growing stages..

Immune supportMetabolic health

High relevance

Almond Mushroom · 2018 · Journal Article · International journal of biological macromolecules

Structure and conformation of α-glucan extracted from Agaricus blazei Murill by high-speed shearing homogenization.

Agaricus blazei Murill is an edible and medicinal mushroom favored in many countries, by virtue of both its delicious taste and its potential health benefits such as its purported anticancer activity..

Oncology

High relevance

Chaga · 2018 · Research Article · Molecules (Basel, Switzerland)

Structure Characterization and Hypoglycaemic Activities of Two Polysaccharides from Inonotus obliquus.

In the present study, two polysaccharides (HIOP1-S and HIOP2-S) were isolated and purified from Inonotus obliquus using DEAE-52 cellulose and Sephadex G-100 column chromatography. The structural characterization and in vitro and in vivo hypoglycaemic activities of these molecules were investigated..

Immune supportMetabolic healthSkin & hydration

High relevance

Lion's Mane · 2018 · Journal Article · Food & function

Structure characterization of a novel polysaccharide from Hericium erinaceus fruiting bodies and its immunomodulatory activities.

A novel polysaccharide fraction (HEP-S) was extracted and isolated from the fruiting bodies of Hericium erinaceus. Structural characterization revealed that HEP-S had an average molecular weight of 1.83 × 104 Da and consisted of rhamnose, fucose, mannose, glucose and galactose at a molar ratio of 1.47: 0.93: 1.36:….

Immune supportMetabolic health

High relevance

Turkey Tail · 2018 · Research Article · Frontiers in microbiology

The Algicidal Fungus Trametes versicolor F21a Eliminating Blue Algae via Genes Encoding Degradation Enzymes and Metabolic Pathways Revealed by Transcriptomic Analysis.

The molecular mechanism underlying the elimination of algal cells by fungal mycelia has not been fully understood. Here, we applied transcriptomic analysis to investigate the gene expression and regulation at time courses of Trametes versicolor F21a during the algicidal process..

Metabolic health

High relevance

Niu-Chang-Chih · 2018 · Journal Article · Journal of dermatological science

The atopic dermatitis-like lesion and the associated MRSA infection and barrier dysfunction can be alleviated by 2,4-dimethoxy-6-methylbenzene-1,3-diol from Antrodia camphorata.

BACKGROUND: Atopic dermatitis (AD) is an inflammatory skin disease with an associated barrier dysfunction and Staphylococcus aureus infection. The mainstay steroid and calcineurin inhibitor therapy shows some adverse effects..

Immune supportLiver supportSkin & hydration

High relevance

Turkey Tail · 2018 · Journal Article · The Science of the total environment

The effect of operational parameters on the biodegradation of bisphenols by Trametes versicolor laccase immobilized on Hippospongia communis spongin scaffolds.

Due to the rapid growth in quantities of phenolic compounds in wastewater, the development of efficient and environmentally friendly methods for their removal becomes a necessity..

High relevance

Cordyceps · 2018 · Research Article · Canadian respiratory journal

The Function of Ophiocordyceps sinensis in Airway Epithelial Cell Senescence in a Rat COPD Model.

Ophiocordyceps sinensis (O. sinensis) seems to be able to alleviate airway epithelial cell senescence in chronic obstructive pulmonary disease (COPD).

Immune supportRespiratory

High relevance

Shiitake · 2018 · Journal Article · International journal of biological macromolecules

The regulation of inflammation and oxidative status against lung injury of residue polysaccharides by Lentinula edodes.

In present study, two hydrolyzed residue polysaccharides (RPS) of enzymatic-RPS (ERPS) and acidic-RPS (ARPS) were successfully obtained from the residue of Lentinula edodes, and the anti-inflammatory as well as antioxidative effects on lipopolysaccharide-induced (LPS-induced) lung injured mice were investigated..

Immune supportRespiratory

High relevance

Lion's Mane · 2018 · Journal Article · The Journal of antibiotics

Three new cyathane diterpenes with neurotrophic activity from the liquid cultures of Hericium erinaceus.

Three new cyathane diterpenes erinacines T-V (1-3), and two known cyathane diterpenes erinacine A (4) and erinacine P (5) were isolated from the liquid cultures of Hericium erinaceus. The structures of 1-3 were determined by extensive spectroscopic analysis..

OncologyCognition & nerves

High relevance

Yellow Morel · 2018 · Journal Article · Microbial pathogenesis

Total flavones of fermentation broth by co-culture of Coprinus comatus and Morchella esculenta induces an anti-inflammatory effect on LPS-stimulated RAW264.7 macrophages cells via the MAPK signaling pathway.

The inflammatory cellular model of RAW264.7 cells induced by lipopolysaccharide (LPS) has always been used to investigate the effect of anti-inflammatory agents in vitro..

OncologyImmune supportEnergy & fatigue

High relevance

Yellow Morel · 2018 · Journal Article · International journal of medicinal mushrooms

Traditional Knowledge of Gucchi, Morchella esculenta (Ascomycetes), in Doda District, Jammu and Kashmir, India.

The gucchi mushroom, Morchella esculenta, commonly known as the morel, is called thunthoo in the Bhaderwahi dialect spoken in District Doda of Jammu and Kashmir, India, and is an expensive food item that grows wild and is collected manually. Its nutritive and medicinal values are acknowledged..

Gut & microbiomeSkin & hydration

High relevance

Turkey Tail · 2018 · Journal Article · Natural product research

Trametes versicolor ethanol extract, a promising candidate for health-promoting food supplement.

This study aimed to estimate antiradical, antioxidant (AO) and cytotoxic activities of the fungus Trametes versicolor ethanol fruiting body extract. The extract was found to effectively scavenge both O2•- and NO• (29.62 and 52.48 μg/mL, respectively)..

Oncology

High relevance

Snow Fungus · 2018 · Research Article · Analytical cellular pathology (Amsterdam)

Tremella fuciformis Polysaccharides Attenuate Oxidative Stress and Inflammation in Macrophages through miR-155.

AIM: To investigate the function of Tremella fuciformis polysaccharides (TFPS) in LPS-induced inflammation and oxidative stress of macrophages. METHODS: RAW264.7 cells were pretreated with TFPS and then stimulated with 0.1 μg/ml LPS.

Immune supportEnergy & fatigue

High relevance

Zhu Ling · 2017 · Journal Article · Yao xue xue bao = Acta pharmaceutica Sinica

[Molecular cloning and prokaryotic expression of a type II ribosome inactivating protein from Polyporus umbellatus].

A type Ⅱ ribosome inactivating protein (RIP) gene was cloned from Polyporus umbellatus sclerotia by RT-PCR method. The full open reading frame cDNA sequence of this gene was 873 bp in length and encoded a 290-aa protein with a molecular weight of 32.33 kDa and an isoelectric point of 5.58..

High relevance

Niu-Chang-Chih · 2017 · Research Article · Polymers

A Novel Heterogalactan from Antrodia camphorata and Anti-Angiogenic Activity of Its Sulfated Derivative.

A heterogalactan, named ACW0, was extracted from Antrodia camphorata and purified by anion exchange and gel permeation chromatography. It was composed of galactose (94.98%), traces of mannose (2.41%), and fucose (2.61%), with its molecular weight estimated to be 13.5 k Da..

Immune support

High relevance

Lion's Mane · 2017 · Research Article · PloS one

A unique polysaccharide purified from Hericium erinaceus mycelium prevents oxidative stress induced by H2O2 in human gastric mucosa epithelium cell.

Hericium erinaceus (HE) has been used both as a traditional Chinese medicine and home remedy for treatment of gastric and duodenal ulcers and gastritis. EP-1, a purified polysaccharide isolated from HE mycelium, has recently been identified as the active component responsible for HE anti-gastritis activity..

Immune supportEnergy & fatigue

High relevance

Maitake · 2017 · Research Article · Oncotarget

A water-soluble polysaccharide from Grifola frondosa induced macrophages activation via TLR4-MyD88-IKKβ-NF-κB p65 pathways.

Here, the immunomodulatory effects of water-soluble polysaccharide from Grifola frondosa on RAW264.7 macrophages and its molecular mechanisms were investigated. G.

Immune support

High relevance

Mesima · 2017 · Research Article · Food science and biotechnology

Anti-allergic and anti-inflammatory activity of Phellinus linteus grown on Panax ginseng.

Panax ginseng (PG) or Phellinus linteus (PL) have been widely used as traditional medicine owing to their many biological activities, including anti-inflammatory and anti-allergic activities. Previously, our group produced PL that was grown on PG media (PGP) to enhance anti-cancer activities of PGP..

OncologyImmune support

High relevance

Chaga · 2017 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Anti-diabetic effects of Inonotus obliquus polysaccharides in streptozotocin-induced type 2 diabetic mice and potential mechanism via PI3K-Akt signal pathway.

Polysaccharides are the main components of mushroom Inonotus obliquus (I. obliquus) with antihyperglycemic activities.

Immune supportMetabolic healthLiver support

High relevance

Chaga · 2017 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Anti-diabetic effects of Inonotus obliquus polysaccharides-chromium (III) complex in type 2 diabetic mice and its sub-acute toxicity evaluation in normal mice.

Polysaccharides are important bioactive ingredients from Inonotus obliquus. This study aimed to synthesize and characterize a novel I.

Immune supportMetabolic health

High relevance

Maitake · 2017 · Journal Article · International journal of medicinal mushrooms

Anti-Inflammation and Lipogenic Inhibition of Taiwanofungus salmonea Mycelium and Grifola frondosa Fruiting Body.

A long-term inflammatory response can cause the development of nonalcoholic steatohepatitis (NASH), which is mainly caused by abnormal metabolism of lipids in the liver..

Immune supportEnergy & fatigueLiver support

High relevance

Maitake · 2017 · Journal Article · International journal of food science & technology

Anti‐inflammatory properties of high pressure‐assisted extracts of Grifola frondosa in lipopolysaccharide‐activated RAW 264.7 macrophages

The aim of this study was to determine the in vitro anti‐inflammatory properties of the shake extract (SE) and the high pressure‐assisted extract (PE) of the mycelia of Grifola frondosa in a lipopolysaccharide‐stimulated RAW 264.7 macrophage model..

Immune support

High relevance

Chaga · 2017 · Research Article · PloS one

Antidiabetic activities of polysaccharides separated from Inonotus obliquus via the modulation of oxidative stress in mice with streptozotocin-induced diabetes.

This study evaluated the effects of Inonotus obliquus polysaccharides (IOs) on diabetes and other underlying mechanisms related to inflammatory factors and oxidative stress in a mouse model of streptozotocin (STZ)-induced diabetes..

Immune supportMetabolic health

High relevance

Enoki · 2017 · Journal Article · Carbohydrate polymers

Antimicrobial and antioxidant activities of Flammulina velutipes polysaccharides and polysaccharide-iron(III) complex [corrected].

FVP is polysacchrides obtained from Flammulina velutipes. A polysacchride named FVP2 was isolated from FVP by DEAE cellulose-52 chromatography and Sephadex G-100 size-exclusion chromatography.

Immune supportLiver support

High relevance

Maitake · 2017 · Journal Article · International journal of biological macromolecules

Antioxidant, antibacterial and anti-aging activities of intracellular zinc polysaccharides from Grifola frondosa SH-05.

In present work, the strain of Grifola frondosa SH-05 was used as a vector of zinc biotransformation to produce the IZPS. The bioactivities including antioxidant and antibacterial activities in vitro and anti-aging properties in vivo of IZPS were investigated comparing with the IPS..

Immune supportSkin & hydration

High relevance

Niu-Chang-Chih · 2017 · Journal Article · Fitoterapia

Antiproliferative activity of the Antrodia camphorata secondary metabolite 4,7-dimethoxy-5-methylbenzo[d][1,3]dioxole and analogues.

Oncology

High relevance

Niu-Chang-Chih · 2017 · Journal Article · Journal of ethnopharmacology

Antrodia camphorata inhibits metastasis and epithelial-to-mesenchymal transition via the modulation of claudin-1 and Wnt/β-catenin signaling pathways in human colon cancer cells.

ETHNOPHARMACOLOGICAL RELEVANCE: Antrodia camphorata (AC) is a well known traditional Chinese medicinal mushroom in Taiwan, has been used to treat various diseases including cancer..

OncologyGut & microbiome

High relevance

Niu-Chang-Chih · 2017 · Journal Article · Journal of agricultural and food chemistry

Antroquinonol, a Ubiquinone Derivative from the Mushroom Antrodia camphorata, Inhibits Colon Cancer Stem Cell-like Properties: Insights into the Molecular Mechanism and Inhibitory Targets.

Antroquinonol (ANQ) is a ubiquinone derivative from the unique mushroom Antrodia camphorata, which exhibits broad-spectrum bioactivities. The effects of ANQ on cancer stem cell-like properties in colon cancer, however, remain unclear.

OncologyGut & microbiome

High relevance

Enoki · 2017 · Research Article · AMB Express

Biodegradation of ramie stalk by Flammulina velutipes: mushroom production and substrate utilization.

In the textile industry, ramie stalk is byproducts with a low economic value. The potential use of this leftover as a substrate ingredient for Flammulina velutipes (F.

High relevance

Shiitake · 2017 · Journal Article · Plant disease

Biological and Molecular Characteristics of a Novel Partitivirus Infecting the Edible Fungus Lentinula edodes.

A new partitivirus named Lentinula edodes partitivirus 1 (LePV1) was isolated from a diseased L. edodes strain with severe degeneration of the mycelium and imperfect browning in bag cultures..

Respiratory

High relevance

Turkey Tail · 2017 · Journal Article · Journal of microbiology and biotechnology

Characterization of Dye Decolorization in Cell-Free Culture Broth of Trametes versicolor CBR43.

The dye decolorization rate in a cell-free culture broth of the white-rot fungus Trametes versicolor CBR43 was studied, including the effects of inhibitors of NaCl, Zn(II), and Cd(II) on dye decolorization activity..

High relevance

Lion's Mane · 2017 · Research Article · International journal of molecular sciences

Chemical Constituents from Hericium erinaceus Promote Neuronal Survival and Potentiate Neurite Outgrowth via the TrkA/Erk1/2 Pathway.

Hericium erinaceus is a culinary-medicinal mushroom used traditionally in Eastern Asia to improve memory. In this work, we investigated the neuroprotective and neuritogenic effects of the secondary metabolites isolated from the MeOH extract of cultured mycelium of H.

Cognition & nerves

High relevance

Zhu Ling · 2017 · Research Article · Acta pharmaceutica Sinica. B

Cloning and expression of three thaumatin-like protein genes from Polyporus umbellatus.

Genes encoding thaumatin-like protein (TLPs) are frequently found in fungal genomes. However, information on TLP genes in Polyporus umbellatus is still limited.

High relevance

Turkey Tail · 2017 · Journal Article · Current microbiology

Co-culturing Effects of Coexisting Bacteria on Wood Degradation by Trametes versicolor.

White-rot fungi are the main decomposers of wood cell-wall polymer in forest ecosystems. Little is known, however, about the interactions between white-rot fungi and other coexisting microorganisms in decayed wood..