MycoData
Medicinal fungi research database
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Cognition & nerves
Cognition, nerve growth factor, neuroprotection, memory, and brain-health papers.
Species records
Species record
Oyster Mushroom
Pleurotus ostreatus
- Studies
- 1,947
- Avg relevance
- 53
- Latest
- 2026
Species record
Reishi · Lingzhi
Ganoderma lucidum
- Studies
- 1,830
- Avg relevance
- 60
- Latest
- 2026
Species record
Turkey Tail · Yun Zhi
Trametes versicolor
- Studies
- 1,828
- Avg relevance
- 41
- Latest
- 2026
Species record
Shiitake · Hua Gu
Lentinula edodes
- Studies
- 1,766
- Avg relevance
- 60
- Latest
- 2026
Species record
Cordyceps · Scarlet Club
Cordyceps militaris
- Studies
- 1,635
- Avg relevance
- 67
- Latest
- 2026
Species record
Cordyceps · Caterpillar Fungus
Ophiocordyceps sinensis
- Studies
- 1,576
- Avg relevance
- 59
- Latest
- 2026
Species record
Almond Mushroom · ABM
Agaricus blazei
- Studies
- 1,441
- Avg relevance
- 54
- Latest
- 2026
Species record
Enoki · Winter Mushroom
Flammulina velutipes
- Studies
- 1,403
- Avg relevance
- 47
- Latest
- 2026
Species record
King Oyster · Eryngii
Pleurotus eryngii
- Studies
- 1,278
- Avg relevance
- 60
- Latest
- 2026
Species record
Maitake · Hen of the Woods
Grifola frondosa
- Studies
- 1,276
- Avg relevance
- 48
- Latest
- 2026
Species record
Snow Fungus · Silver Ear
Tremella fuciformis
- Studies
- 1,052
- Avg relevance
- 29
- Latest
- 2026
Species record
Lion's Mane · Yamabushitake
Hericium erinaceus
- Studies
- 862
- Avg relevance
- 67
- Latest
- 2026
Species record
Chaga
Inonotus obliquus
- Studies
- 738
- Avg relevance
- 65
- Latest
- 2026
Species record
Mesima · Sanghwang
Phellinus linteus
- Studies
- 722
- Avg relevance
- 58
- Latest
- 2026
Species record
Niu-Chang-Chih
Antrodia camphorata
- Studies
- 496
- Avg relevance
- 63
- Latest
- 2026
Species record
Nameko · Nametake
Pholiota microspora
- Studies
- 421
- Avg relevance
- 29
- Latest
- 2026
Species record
Yellow Morel
Morchella esculenta
- Studies
- 392
- Avg relevance
- 42
- Latest
- 2026
Species record
Zhu Ling · Umbrella Polypore
Polyporus umbellatus
- Studies
- 263
- Avg relevance
- 55
- Latest
- 2026
Species record
Wood Ear · Kikurage
Auricularia auricula-judae
- Studies
- 254
- Avg relevance
- 51
- Latest
- 2026
Species record
Agarikon · Quinine Conk
Fomitopsis officinalis
- Studies
- 47
- Avg relevance
- 55
- Latest
- 2026
Articles
1,418 results
Showing 451–500 of 1,418
Lion's Mane · 2014 · Review · Applied microbiology and biotechnology
Medicinal properties of Hericium erinaceus and its potential to formulate novel mushroom-based pharmaceuticals.
Hericium erinaceus is an important mushroom with edible values and medicinal properties. Both the mycelium and the fruiting bodies contain many bioactive compounds with drug efficacy..
Enoki · 1999 · Journal Article · Edible Fungi of China
Determination and analysis of protein and amino acid content in Flammulina velutipes
A system for machine assisted karyotyping and chromosome analysis has been developed. The system uses a drum- or TV-scanner as input device, runs provisionally in 32 K memory, and also allows human interaction on several stages..
Enoki · 1997 · Journal Article · Edible Fungi of China
Effects of light quality on the growth and development of the fruitbody of Flammulina velutipes (Fr.) Sing.
The patient is a 17-year-old female. She was suffering from dwarfism, irregular menstruation and obesity.
Shiitake · 2026 · Journal Article · Food Research International
Based on the umami-transformer machine learning model: Screening of umami peptides from ultrasound-assisted enzymatic hydrolysis of shiitake mushrooms and study on their flavor mechanism
This study aimed to optimize ultrasound-assisted enzymatic hydrolysis for umami peptide preparation from shiitake mushrooms, develop a reliable predictive screening model for umami peptides, and clarify the molecular mechanism underlying the umami taste of these peptides..
Shiitake · 2026 · Journal Article · Food research international (Ottawa, Ont.)
Based on the umami-transformer machine learning model: Screening of umami peptides from ultrasound-assisted enzymatic hydrolysis of shiitake mushrooms and study on their flavor mechanism.
This study aimed to optimize ultrasound-assisted enzymatic hydrolysis for umami peptide preparation from shiitake mushrooms, develop a reliable predictive screening model for umami peptides, and clarify the molecular mechanism underlying the umami taste of these peptides..
Almond Mushroom · 2026 · Research Article · ESMO open
Phase I study of ABM-1310 as monotherapy and in combination with cobimetinib for BRAF-mutated advanced solid tumors: safety, efficacy, and dose expansion.
BACKGROUND: ABM-1310 is an investigational, orally bioavailable BRAF V600 inhibitor with high blood-brain barrier (BBB) penetration. PATIENTS AND METHODS: This first-in-human, phase I trial evaluated patients with BRAF V600-mutated advanced solid tumors, including brain metastases (≤3 cm) and primary central nervous….
Oyster Mushroom · 2025 · Journal Article · Computers and Electronics in Agriculture
A novel Mask R-CNN-based tracking pipeline for oyster mushroom cluster growth monitoring in time-lapse image datasets
This paper introduces a novel deep learning-based instance segmentation tracking pipeline for the continuous monitoring of oyster mushroom cluster growth in a series of images at different time intervals..
Cordyceps · 2025 · Research Article · Frontiers in neurology
Effectiveness of fermentation broth of Cordyceps sinensis for primary insomnia: a randomized clinical trial with digital health tool.
BACKGROUND: Cordyceps sinensis is widely used in Traditional Chinese Medicine and dietary supplements to tonify the kidney, lung, and heart, as well as to calm the mind. The fermentation broth of Cordyceps sinensis (FBCS), containing cordycepin, has shown potential in various healthcare applications..
Chaga · 2025 · Research Article · Antioxidants (Basel, Switzerland)
Impact of a Formulation Containing Chaga Extract, Coenzyme Q10, and Alpha-Lipoic Acid on Mitochondrial Dysfunction and Oxidative Stress: NMR Metabolomic Insights into Cellular Energy.
OBJECTIVES: The aim of this study was to evaluate the impact of a novel antioxidant formulation (RE:PAIR, RP-25) containing CoQ10, alpha-lipoic acid, and Chaga extract on mitochondrial dysfunction and oxidative stress..
Shiitake · 2025 · Research Article · Frontiers in plant science
Machine vision-based detection of browning maturity in shiitake cultivation sticks.
INTRODUCTION: Accurate monitoring of pigmentation changes during the browning stage of shiitake cultivation sticks is essential for assessing substrate maturity, forecasting mushroom emergence, and improving cultivation quality..
Shiitake · 2025 · Research Article · Frontiers in plant science
Machine vision-based detection of key traits in shiitake mushroom caps.
This study puts forward a machine vision-based prediction method to solve the problem regarding the measurement of traits in shiitake mushroom caps during the shiitake mushroom breeding process. It enables precise phenotyping through accurate image acquisition and analysis..
Cordyceps · 2025 · Journal Article · Analytical and bioanalytical chemistry
Rapid metabolic profiling and authentication of Cordyceps using ambient ionization mass spectrometry and machine learning.
Cordyceps sinensis, a symbiotic organism formed between a fungus and an insect, is celebrated for its substantial medicinal benefits and economic significance in traditional Chinese medicine..
Shiitake · 2025 · Research Article · Nutrients
Shiitake Mushroom-Derived Vesicle-like Nanoparticles Improve Cognitive Function and Reshape Gut Microbiota and Fecal Metabolome in Aged Mice.
BACKGROUND/OBJECTIVES: Population aging and its associated chronic conditions have become an unprecedented challenge in the United States and worldwide. Many aged individuals experience certain forms of cognitive decline, which increases their risk of developing a pre-dementia condition called mild cognitive….
Reishi · 2025 · Research Article · Journal of fungi (Basel, Switzerland)
What Are "Lingzhi Wang" or "Zhu Lingzhi"? Notes on Ganoderma (Ganodermataceae, Polyporales) Species Characterized by Diminutive Pilei and Gracile Stipes from Hainan Island, Tropical China.
Species of Ganoderma (Ganodermataceae, Polyporales) have been extensively utilized in traditional Chinese medicine for over two millennia, owing to their remarkable medicinal properties and diverse chemical constituents. Hainan Island, located in tropical China, harbors a rich diversity of Ganoderma species..
Cordyceps · 2024 · Journal Article · International journal of biological macromolecules
Exploratory studies of the antidepressant effect of Cordyceps sinensis polysaccharide and its potential mechanism.
Cordyceps sinensis, a traditionally prized medicinal fungus, contains polysaccharides as one of its main bioactive constituents, known for their significant immunomodulatory properties..
Reishi · 2024 · Research Article · Integrative medicine research
Symptom improvements and adverse effects with Reishi mushroom use: A Cross-Sectional survey of cancer patients.
BACKGROUND: Reishi, a medicinal mushroom, is increasingly used for symptom control by cancer patients worldwide. However, data around patients' experiences with Reishi in oncology are lacking, limiting safe, effective clinical applications..
Almond Mushroom · 2024 · Research Article · Neuroscience applied
The effect of ABM on attentional networks and stress-induced emotional reactivity in a mixed clinical sample with depression: A randomized sham-controlled trial.
Research on the efficacy of Attention Bias Modification for depressive symptoms has predominantly yielded unfavorable outcomes. Despite adhering to rigorous conventions in randomized controlled trials, findings from these studies have indicated minimal effect sizes, thereby raising concerns about their limited….
Cordyceps · 2023 · Review · Nutrients
Unique Bioactives from Zombie Fungus (Cordyceps) as Promising Multitargeted Neuroprotective Agents.
Cordyceps, also known as "zombie fungus", is a non-poisonous mushroom that parasitizes insects for growth and development by manipulating the host system in a way that makes the victim behave like a "zombie". These species produce promising bioactive metabolites, like adenosine, β-glucans, cordycepin, and ergosterol..
Cordyceps · 2022 · Review · Frontiers in pharmacology
Mechanism of Cordyceps sinensis and its Extracts in the Treatment of Diabetic Kidney Disease: A Review.
Diabetic kidney disease (DKD) is the major reason of chronic kidney disease (CKD)-caused end-stage renal failure (ESRF), and leads to high mortality worldwide. At present, the treatment of DKD is mainly focused on controlling the hyperglycemia, proteinuria, and hypertension, but is insufficient on the effective delay….
Cordyceps · 2021 · Review · Medicinal chemistry (Shariqah (United Arab Emirates))
Prospects for Discovering the Secondary Metabolites of Cordyceps Sensu Lato by the Integrated Strategy.
BACKGROUND: Some species of Cordyceps sensu lato are famous Chinese herbs with significant biological activities, often used as edible food and traditional medicine in China..
Almond Mushroom · 2026 · Randomized Controlled Trial · The American journal of psychiatry
Primary Prevention of PTSD Symptoms in Combat-Deploying Soldiers Using Attention Bias Modification: A Randomized Controlled Trial.
OBJECTIVE: Evidence suggests that attentional threat avoidance is associated with increased risk for posttraumatic stress disorder (PTSD). This study evaluated the efficacy of two attention bias modification (ABM) protocols designed to enhance attention toward threats as a primary prevention of PTSD..
Almond Mushroom · 2026 · Randomized Controlled Trial · Alcohol (Fayetteville, N.Y.)
Your team is counting on you: Digital gamification and team motivation in alcohol aftercare.
BACKGROUND: Relapse after inpatient treatment for alcohol dependence is frequent, particularly within the first three months post-discharge. Cognitive Bias Modification (CBM), and specifically alcohol Approach Bias Modification (ABM), has demonstrated benefits in inpatient care, but its efficacy for aftercare remains….
Almond Mushroom · 2025 · Randomized Controlled Trial · Translational psychiatry
5-HTTLPR does not moderate the effect of attention bias modification for depression: a randomized sham-controlled trial.
The 5-HTTLPR polymorphism in the serotonin transporter gene SLC6A4 has previously been dubbed a plasticity marker. Within the 5-HTTLPR polymorphism, a SNP (rs25531) in the L-allele in the promoter region, affects the transcription efficacy of the SCL6A4, leading to functionally important differences related to….
Almond Mushroom · 2025 · Randomized Controlled Trial · Journal of anxiety disorders
A randomized clinical trial investigating the clinical impact of a game-based digital therapeutic for social anxiety disorder.
The objective of this study was to determine if a novel game-based digital therapeutic intervention reduced anxiety symptom severity in adults with clinically elevated symptoms of social anxiety disorder (SAD)..
Almond Mushroom · 2025 · Randomized Controlled Trial · Behaviour research and therapy
Active positive searching versus passive negative avoidance: A comparative investigation of large-scale offline attention bias modification training in nonclinical adolescents.
Attentional bias (AB), characterized by a disproportionate allocation of attention toward threat-related stimuli, constitutes a well-established cognitive mechanism underlying anxiety disorders..
Almond Mushroom · 2025 · Randomized Controlled Trial · Journal of behavior therapy and experimental psychiatry
Attend to the positive while feeling anxious: The effect of state anxiety on the effectiveness of Attentional Bias Modification.
BACKGROUND AND OBJECTIVES: Elevating state anxiety during Attentional Bias Modification (ABM) may improve its effectiveness by matching the emotional state experienced during the training with the emotional state under which it is intended that the learned pattern of attentional bias will subsequently operate..
Almond Mushroom · 2025 · Randomized Controlled Trial · The journal of pain
Attention and nocebo hyperalgesia: Testing a novel virtual reality attention bias modification paradigm.
Nocebo effects in pain (nocebo hyperalgesia) have received significant attention recently, with negative expectancies and anxiety proposed to be explanatory factors. While both expectancy and anxiety can bias attention, attention has been rarely explored as a potential mechanism involved in nocebo hyperalgesia..
Almond Mushroom · 2025 · Randomized Controlled Trial · Behavioural and cognitive psychotherapy
Combining internet-delivered cognitive behavioural therapy and attention bias modification for reducing depressive symptoms in firefighters: a randomized controlled trial.
BACKGROUND: Firefighters are frequently exposed to traumatic events and stressful environments and are at particularly high risk of depressive symptoms. AIMS: The present study aimed to examine the impact of a combined internet-delivered cognitive behavioral therapy (iCBT) and attention bias modification (ABM)….
Almond Mushroom · 2025 · Randomized Controlled Trial · Neuropsychopharmacology reports
Effectiveness of Attentional Bias Modification Combined With Cognitive Behavioral Therapy in Reducing Relapse Risk and Cravings in Male Patients With Alcohol Use Disorder: A Quasi-Randomized Controlled Trial.
BACKGROUND: Alcohol use disorder (AUD) is characterized by severe dependence on alcohol, poor impulse control, and heightened attention to alcohol-related cues. Attention bias modification (ABM) retrains individuals to distract attention from alcohol-related cues..
Almond Mushroom · 2025 · Randomized Controlled Trial · Brain research
Prefrontal transcranial direct current stimulation enhances the analgesic effects of attention bias modification: a randomized controlled trial.
This study aimed to investigate whether high-definition transcranial direct current stimulation (HD-tDCS) augmented the effect of attentional bias modification (ABM) on pain perception and to explore the potential neuroimaging mechanism by functional infrared spectroscopy (fNIRS)..
Almond Mushroom · 2024 · Randomized Controlled Trial · Journal of behavior therapy and experimental psychiatry
Inhibition moderates the effect of attentional bias modification for reducing residual depressive symptoms: A randomized sham-controlled clinical trial.
OBJECTIVES: Residual symptoms represent risk factor for relapse. Attention bias modification (ABM) may reduce clinical and sub-clinical depressive symptoms, indicating that is may be of relevance when preventing relapse..
Almond Mushroom · 2024 · Randomized Controlled Trial · European archives of psychiatry and clinical neuroscience
Neural mechanisms underlying attentional bias modification in fibromyalgia patients: a double-blind ERP study.
There is a growing interest in the potential benefits of attentional bias modification (ABM) training in chronic pain patients. However, studies examining the effectiveness of ABM programs in fibromyalgia patients have demonstrated inconclusive effects on both behavioral indices and clinical symptoms..
Almond Mushroom · 2024 · Randomized Controlled Trial · Scientific reports
The effect of attentional bias modification on positive affect dynamics.
Negative attentional bias and alterations in positive affect dynamics constitute emotional vulnerability to depression. Attentional bias modification (ABM) aims to reduce emotional vulnerability to depression by fostering attentional deployment towards positive stimuli..
Lion's Mane · 2015 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms
Anti-Gastric Ulcer Activity of Polysaccharide Fraction Isolated from Mycelium Culture of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes).
Hericium erinaceus is a culinary-medicinal mushroom that is used in traditional medicine, in folk medicine, and as medicinal cuisine in Asian countries such as China, Japan, and Korea. H..
Almond Mushroom · 2015 · Research Support, Non U.S. Gov'T · Malaria journal
Effect of mushroom Agaricus blazei on immune response and development of experimental cerebral malaria.
BACKGROUND: Cerebral malaria (CM) is debilitating and sometimes fatal. Disease severity has been associated with poor treatment access, therapeutic complexity and drug resistance and, thus, alternative therapies are increasingly necessary..
Lion's Mane · 2015 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms
Lion's Mane, Hericium erinaceus and Tiger Milk, Lignosus rhinocerotis (Higher Basidiomycetes) Medicinal Mushrooms Stimulate Neurite Outgrowth in Dissociated Cells of Brain, Spinal Cord, and Retina: An In Vitro Study.
Neurodegenerative disease is defined as a deterioration of the nervous system in the intellectual and cognitive capabilities. Statistics show that more than 80-90 million individuals age 65 and above in 2050 may be affected by neurodegenerative conditions like Alzheimer's and Parkinson's disease..
Cordyceps · 2015 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms
Protective Efficacy of the Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycetes), from India in Neuronal Hippocampal Cells against Hypoxia.
This study demonstrated the protective efficiency of extracts of the Indian variety of Ophiocordyceps sinensis (=Cordyceps sinensis) (CSEs) in HT22 (murine hippocampal) cells under hypoxic conditions..
Cordyceps · 2015 · Research Support, Non U.S. Gov'T · Molecular medicine reports
Purification of polysaccharides from Cordyceps militaris and their anti‑hypoxic effect.
Acute mountain sickness, one of the most common altitude diseases, causes lung and brain injury. The present study aimed to investigate the anti‑hypoxic effect of purified polysaccharides extracted from Cordyceps militaris..
Lion's Mane · 2015 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms
Systemic Screening of Strains of the Lion's Mane Medicinal Mushroom Hericium erinaceus (Higher Basidiomycetes) and Its Protective Effects on Aβ-Triggered Neurotoxicity in PC12 Cells.
Hericium erinaceus possesses multiple medicinal values. To date, however, there have been few studies of the systemic screening of H.
Lion's Mane · 2014 · Research Support, Non U.S. Gov'T · International journal of molecular sciences
Protective effects of Hericium erinaceus mycelium and its isolated erinacine A against ischemia-injury-induced neuronal cell death via the inhibition of iNOS/p38 MAPK and nitrotyrosine.
Hericium erinaceus, an edible mushroom, has been demonstrated to potentiate the effects of numerous biological activities. The aim of this study was to investigate whether H..
King Oyster · 2013 · Research Support, Non U.S. Gov'T · Journal of lipid research
Binding of a pleurotolysin ortholog from Pleurotus eryngii to sphingomyelin and cholesterol-rich membrane domains.
A mixture of sphingomyelin (SM) and cholesterol (Chol) exhibits a characteristic lipid raft domain of the cell membranes that provides a platform to which various signal molecules as well as virus and bacterial proteins are recruited..
King Oyster · 2013 · Research Support, Non U.S. Gov'T · Biological & pharmaceutical bulletin
Improvement of Depression-Like Behavior and Memory Impairment with the Ethanol Extract of Pleurotus eryngii in Ovariectomized Rats
Ethanol extract of Pleurotus eryngii (DC.) QUÉL has estrogen-like activities that protect against bone loss caused by estrogen deficiency. In the present study, we investigated the effect of P.
Lion's Mane · 2013 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms
Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia.
Neurotrophic factors are important in promoting the growth and differentiation of neurons. Nerve growth factor (NGF) is essential for the maintenance of the basal forebrain cholinergic system.
Almond Mushroom · 2012 · Research Support, Non U.S. Gov'T · In vivo (Athens, Greece)
Evaluation of genotoxicity and subclinical toxicity of Agaricus blazei Murrill in the Ames test and in histopathological and biochemical analysis.
This study was conducted in order to assess the safety and tolerability of Agaricus blazei Murrill (ABM) in general toxicological studies by Ames tests in vitro and in 28-day feeding toxicity experiments..
Snow Fungus · 2012 · Patent · journal metadata
PRODUCING METHOD OF EXTRACT OF TREMELLA FUCIFORMIS USING ENZYMES AND THE COMPOSITION FOR IMPROVING MEMORY STRENGTH COMPRISING THE EXTRACT
PURPOSE: A composition containing Tremella fuciformis extract is provided to improve yield and to recover neural cells. CONSTITUTION: A method for preparing Tremella fuciformis extract comprises: a step of performing hot water extraction of Tremella fuciformis under an acidic condition and a step of treating enzyme to….
Chaga · 2011 · Research Support, Non U.S. Gov'T · Food & function
Amelioration of scopolamine induced cognitive dysfunction and oxidative stress by Inonotus obliquus - a medicinal mushroom.
The present study was aimed to investigate the cognitive enhancing and anti-oxidant activities of Inonotus obliquus (Chaga) against scopolamine-induced experimental amnesia. Methanolic extract of Chaga (MEC) at 50 and 100 mg kg (-1)doses were administered orally for 7 days to amnesic mice..
Maitake · 2011 · Research Support, Non U.S. Gov'T · Pharmaceutical biology
Enhancement of in vitro and in vivo anticancer activities of polysaccharide peptide from Grifola frondosa by chemical modifications.
CONTEXT: Grifola frondosa (Polyporaceae), maitake, is a widely consumed edible mushroom in some Asian countries. The fruit bodies and mycelia of maitake have shown different bioactive compounds with anticancer and other therapeutic properties..
Niu-Chang-Chih · 2010 · Research Support, Non U.S. Gov'T · International urology and nephrology
Protective effect of Antrodia camphorata on bladder ischemia/reperfusion injury.
INTRODUCTION: Obstructive bladder dysfunction is directly related to ischemia/reperfusion injury characterized by damage to nerves, synapses and smooth muscle cells within the bladder wall. Antrodia Camphorata (AC) has significant antioxidant, antiinflammatory and cell-cycle inhibition properties..
Mesima · 2009 · Patent · journal metadata
A COMPOUND EXTRACTED FROM PHELLINUS LINTEUS FOR PROTECTION OF NEURONAL CELLS, METHOD FOR PREPARING THE COMPOUND AND A COMPOSITION COMPRISING THE COMPOUND AS AN EFFECTIVE COMPONENT
A compound extracted from phellinus linteus for protecting neuronal cells is provided to protect nerve cells by suppressing the extinction of nerve cells mediated by hydrogen peroxide..
Snow Fungus · 2009 · Patent · journal metadata
THE COMPOSITION FOR IMPROVING MEMORY STRENGTH COMPRISING EXTRACT OF TREMELLA FUCIFORMIS AND METHOD OF PREPERATION THEREOF
A composition for hypermnesia inlucing hydrothermal extract of tremella fuciformis is provided to improve maintenance of memory power by promoting growth of neural spines and protecting of nerve cells..