MycoData
Medicinal fungi research database
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Liver support
Hepatoprotection, liver enzymes, toxin exposure, and hepatic injury literature.
Species records
Species record
Oyster Mushroom
Pleurotus ostreatus
- Studies
- 1,947
- Avg relevance
- 53
- Latest
- 2026
Species record
Reishi · Lingzhi
Ganoderma lucidum
- Studies
- 1,830
- Avg relevance
- 60
- Latest
- 2026
Species record
Turkey Tail · Yun Zhi
Trametes versicolor
- Studies
- 1,828
- Avg relevance
- 41
- Latest
- 2026
Species record
Shiitake · Hua Gu
Lentinula edodes
- Studies
- 1,766
- Avg relevance
- 60
- Latest
- 2026
Species record
Cordyceps · Scarlet Club
Cordyceps militaris
- Studies
- 1,635
- Avg relevance
- 67
- Latest
- 2026
Species record
Cordyceps · Caterpillar Fungus
Ophiocordyceps sinensis
- Studies
- 1,576
- Avg relevance
- 59
- Latest
- 2026
Species record
Almond Mushroom · ABM
Agaricus blazei
- Studies
- 1,441
- Avg relevance
- 54
- Latest
- 2026
Species record
Enoki · Winter Mushroom
Flammulina velutipes
- Studies
- 1,403
- Avg relevance
- 47
- Latest
- 2026
Species record
King Oyster · Eryngii
Pleurotus eryngii
- Studies
- 1,278
- Avg relevance
- 60
- Latest
- 2026
Species record
Maitake · Hen of the Woods
Grifola frondosa
- Studies
- 1,276
- Avg relevance
- 48
- Latest
- 2026
Species record
Snow Fungus · Silver Ear
Tremella fuciformis
- Studies
- 1,052
- Avg relevance
- 29
- Latest
- 2026
Species record
Lion's Mane · Yamabushitake
Hericium erinaceus
- Studies
- 862
- Avg relevance
- 67
- Latest
- 2026
Species record
Chaga
Inonotus obliquus
- Studies
- 738
- Avg relevance
- 65
- Latest
- 2026
Species record
Mesima · Sanghwang
Phellinus linteus
- Studies
- 722
- Avg relevance
- 58
- Latest
- 2026
Species record
Niu-Chang-Chih
Antrodia camphorata
- Studies
- 496
- Avg relevance
- 63
- Latest
- 2026
Species record
Nameko · Nametake
Pholiota microspora
- Studies
- 421
- Avg relevance
- 29
- Latest
- 2026
Species record
Yellow Morel
Morchella esculenta
- Studies
- 392
- Avg relevance
- 42
- Latest
- 2026
Species record
Zhu Ling · Umbrella Polypore
Polyporus umbellatus
- Studies
- 263
- Avg relevance
- 55
- Latest
- 2026
Species record
Wood Ear · Kikurage
Auricularia auricula-judae
- Studies
- 254
- Avg relevance
- 51
- Latest
- 2026
Species record
Agarikon · Quinine Conk
Fomitopsis officinalis
- Studies
- 47
- Avg relevance
- 55
- Latest
- 2026
Articles
1,643 results
Showing 601–650 of 1,643
Niu-Chang-Chih · 2008 · Journal Article · Toxicology and applied pharmacology
In vivo immunomodulatory effects of Antrodia camphorata polysaccharides in a T1/T2 doubly transgenic mouse model for inhibiting infection of Schistosoma mansoni.
Antrodia camphorata (A. camphorata) is a fungus commonly used for treatment of viral hepatitis and cancer in Chinese folk medicine.
Enoki · 2007 · Journal Article · Carbohydrate polymers
Purification, characterization and biological activity on hepatocytes of a polysaccharide from Flammulina velutipes mycelium
A water-soluble polysaccharide named as FVP2 has been isolated from Flammulina velutipes mycelium by hot water extraction, anion-exchange and gel-permeation chromatography..
Niu-Chang-Chih · 2005 · Patent · journal metadata
A new extraction method and application of antrodia camphorata in promoting the energy and the ability of exercise and anti-fatigue
We found a new application of Antrodia camphorata in promoting the Energy and the ability of exercise. We used the gene expression analysis and absorbance value of creatinine-picric acid complex to prove the new application..
Mesima · 2005 · Comparative Study · Biological & pharmaceutical bulletin
Cambodian Phellinus linteus Inhibits Experimental Metastasis of Melanoma Cells in Mice via Regulation of Urokinase Type Plasminogen Activator
Phellinus linteus (PL) is a fungus mainly found in tropical America, Africa and Asian countries including Korea, Japan and China. PL has been traditionally used for the treatment of arthritis, liver damage and cancer..
Niu-Chang-Chih · 2005 · Patent · journal metadata
Process for preparing antrodia camphorata polysaccharide and antrodia camphorata triterpene with micro-prorous adsorptive resin and its product
The present invention provides preparation process of antrodia camphorata polysaccharide and antrodia camphorata triterpene with adsorptive microporous resin and its product, and relates to chromatographic separation technology with adsorptive microporous resin and extraction of effective Chinese medicine component..
Chaga · 2004 · Patent · journal metadata
COMPOSITION COMPRISING EXTRACT OF INONOTUS OBLIQUUS HAVING IMMUNE-ENHANCING AND ANTICANCER ACTIVITIES
PURPOSE: Provided is a pharmaceutical composition comprising the extract of Inonotus obliquus which has immune-enhancing and anticancer activities. The extract of Inonotus obliquus is effectively used for health foods and medicaments for prevention and treatment of adult diseases, such as immunodeficiency diseases and….
Mesima · 2004 · Comparative Study · Journal of ethnopharmacology
Mycelial culture of Phellinus linteus protects primary cultured rat hepatocytes against hepatotoxins.
Hepatoprotective activity of Phellinus linteus was studied using H(2)O(2)- or galactosamine-injured primary cultures of rat hepatocytes as screening systems. The methanolic extract of the mycelial culture of Phellinus linteus significantly protected against hepatotoxins-induced toxicity in primary cultured rat….
Mesima · 2003 · Comparative Study · Biotechnology letters
Inhibition of cytochrome P450 isozymes in rat liver microsomes by polysaccharides derived from Phellinus linteus.
Polysaccharides (0.5, 1 and 3 mg ml(-1)) from cultured broth and mycelia of Phellinus linteus inhibited cytochrome P450 (CYP) 1A1, CYP 1A2, CYP 2B1, and CYP 2E1 activities in rat liver microsomes..
Cordyceps · 2025 · Research Support, Non U.S. Gov'T · Molecular nutrition & food research
Cordyceps-Fermented Chinese Jujube Ameliorates Oxidative Stress and Restores Gut Microbiome in Alcohol-Induced Liver Injury in Mice.
This research investigated the influence of Chinese jujube fermented with Cordyceps kyushuensis extracts on mice with alcohol-induced liver injury (ALI). Our findings highlighted the antioxidant properties of these extracts through various assays and demonstrated potential biochemical effects in ALI mice..
Reishi · 2025 · Review · Journal of ethnopharmacology
Ganoderic acid A: an in-depth review of pharmacological effects and molecular docking analysis.
ETHNOPHARMACOLOGICAL RELEVANCE: Ganoderic acid A (GAA, C30H44O7) is one of the most abundant and active components of Ganoderic acids (GAs). GAs are highly oxidized tetracyclic triterpenoid compounds mainly derived from Ganoderma lucidum (Curtis) P.
Reishi · 2025 · Review · Frontiers in cellular and infection microbiology
Ganodermataceae-current status, research, and development in Lower Mekong Basin.
The family Ganodermataceae encompasses several genera, including the widely studied Ganoderma, which is prominent in traditional medicine for its therapeutic properties..
Almond Mushroom · 2024 · Review · Journal of agricultural and food chemistry
Chemical Structures, Biological Activities, and Biosynthetic Analysis of Secondary Metabolites from Agaricus Mushrooms: A Review.
Agaricus mushrooms are an important genus in the Agaricaceae family, belonging to the order Agaricales of the class Basidiomycota. Among them, Agaricus bisporus is a common mushroom for mass consumption, which is not only nutritious but also possesses significant medicinal properties such as anticancer, antibacterial,….
Reishi · 2023 · Journal Article · Wiadomosci lekarskie (Warsaw, Poland: 1960)
EFFECT OF DRY EXTRACT FROM REISHI MUSHROOMS ON THE STATE OF ANTIOXIDANT SYSTEM IN RATS WITH DMH-INDUCED COLON CARCINOGENESIS.
OBJECTIVE: The aim: To study pro- and antioxidant systems indicators in rats with chemically induced colon carcinogenesis on the background of the reishi mushrooms dry extract use. PATIENTS AND METHODS: Materials and methods: The study was performed on 120 white male rats..
Cordyceps · 2023 · Research Article · Cellular and molecular bioengineering
Enhancing Neurological Competence of Nanoencapsulated Cordyceps/Turmeric Extracts in Human Neuroblastoma SH-SY5Y Cells.
INTRODUCTION: Neurological diseases, including Alzheimer's, Parkinson's diseases, and brain cancers, are reportedly caused by genetic aberration and cellular malfunction..
Chaga · 2023 · Research Article · Antioxidants (Basel, Switzerland)
Isolation, Physicochemical Characterization, and Biological Properties of Inotodiol, the Potent Pharmaceutical Oxysterol from Chaga Mushroom.
Inotodiol, an oxysterol found only in Chaga mushroom, has received attention from the pharmaceutical industry due to its strong antioxidant and anti-allergic activities. However, the production of inotodiol is still challenging, and its fundamental properties have yet to be investigated..
Cordyceps · 2023 · Research Article · Molecules (Basel, Switzerland)
Structural Characterization and Hypoglycemic Function of Polysaccharides from Cordyceps cicadae.
The polysaccharides isolated and purified from different parts of the medicinal fungus Cordyceps cicadae were identified, and three extracts displaying significant biological activities were selected for further study..
Cordyceps · 2023 · Research Article · Nanomaterials (Basel, Switzerland)
The Effect of Nanobubble Water Containing Cordyceps Extract and Withaferin A on Free Fatty Acid-Induced Lipid Accumulation in HepG2 Cells.
Cordyceps extract and withaferin A (Wi-A) are natural compounds that have therapeutic effects on non-alcoholic fatty liver disease (NAFLD). However, their efficacy is limited and a long treatment duration is usually required..
Cordyceps · 2022 · Journal Article · The American journal of Chinese medicine
Cordyceps Improves Obesity and its Related Inflammation via Modulation of Enterococcus cecorum Abundance and Bile Acid Metabolism.
Dysbiotic gut microbiota has been identified as a primary mediator of inherent inflammation that underlies the pathogenesis of obesity. Cordyceps comprises the larval body and the stroma of Cordyceps sinensis (BerK.) Sacc.
Maitake · 2021 · Journal Article · Polski merkuriusz lekarski: organ Polskiego Towarzystwa Lekarskiego
Application of the thick extract from Maitake mushrooms for correction of metabolic disorders under the paracetamol hepatitis in rats.
UNLABELLED: It is known that the violation of one or more functions of the liver, where the basic biochemical processes take place, is reflected in the functional state of many organs and systems, causing severe consequences..
Shiitake · 2021 · Journal Article · Foods (Basel, Switzerland)
Efficacy and Safety of Aronia, Red Ginseng, Shiitake Mushroom, and Nattokinase Mixture on Insulin Resistance in Prediabetic Adults: A Randomized, Double-Blinded, Placebo-Controlled Trial.
We determined whether oral consumption of Aronia, red ginseng, shiitake mushroom, and nattokinase mixture (3.4: 4.1: 2.4: 0.1 w/w; AGM) improved glucose metabolism and insulin resistance in prediabetic adults in a 12-week randomized, double-blinded clinical trial..
Almond Mushroom · 2025 · Journal Article · Journal of oncology pharmacy practice: official publication of the International Society of Oncology Pharmacy Practitioners
Grade 3 cytolysis in a patient with metastatic colorectal cancer consuming a mushroom powder-based alternative therapy.
IntroductionThe use of Complementary Alternative Medicine (CAM) in patients with cancer is increasing. CAM is associated with potential toxicity and drug interactions, particularly with chemotherapy..
Lion's Mane · 2025 · Research Article · International journal of molecular sciences
Investigating the Neuroprotective, Hepatoprotective, and Antimicrobial Effects of Mushroom Extracts.
Mushrooms, renowned for their nutritional value and bioactive compounds, offer potential health benefits, including antioxidants and anti-aging properties. Aging, characterized by cellular and tissue decline, is often associated with autophagy dysfunction, a crucial cellular cleaning process..
Oyster Mushroom · 2025 · Journal Article · Water research
Sticky or thrifty: Divergence in extracellular glycometabolic architecture underpins contrasting fungal bioflocculation strategies.
Fungal-assisted bioflocculation is attracting attention as a chemical-free route for algal bloom mitigation and pollutants sequestration, but its species-specific traits that govern performance remain poorly quantified, hindering rational strain selection and scale-up..
Reishi · 2024 · Research Article · American journal of translational research
Ganoderic acid A attenuated hepatic impairment by down-regulating the intracellular JAK2-STAT3 signaling pathway in induced mushroom poisoning.
BACKGROUND: Mushroom poisoning is one of the most prominent public health problems. However, there is no special antidote so far.
Almond Mushroom · 2023 · Randomized Controlled Trial · Psychological medicine
A randomized controlled trial of supervised remotely-delivered attention bias modification for posttraumatic stress disorder.
BACKGROUND: Many individuals with posttraumatic stress disorder (PTSD) have limited access to first-line treatments, warranting the development of remotely-delivered treatments. Attention bias modification (ABM), targeting perturbed threat-related attentional patterns, shows promise when delivered in-person..
Almond Mushroom · 2021 · Randomized Controlled Trial · PloS one
Effectiveness of attentional bias modification training as add-on to regular treatment in alcohol and cannabis use disorder: A multicenter randomized control trial.
BACKGROUND: Attentional bias for substance-relevant cues has been found to contribute to the persistence of addiction. Attentional bias modification (ABM) interventions might, therefore, increase positive treatment outcome and reduce relapse rates..
Niu-Chang-Chih · 2005 · Journal Article · Journal of agricultural and food chemistry
Mycelia from Antrodia camphorata in Submerged culture induce apoptosis of human hepatoma HepG2 cells possibly through regulation of Fas pathway.
The objective of this study was to investigate the antiproliferative effect and the mechanism of the methanol extracts of mycelia (MEM) form Antrodia camphorata in submerged culture toward HepG2 cells..
Snow Fungus · 2004 · Research Article · Hua zhong nong ye da xue xue bao = Journal Huazhong (Central China) Agricultural University
Mating type factor A and mating pheromone production of Tremella fuciformis
Cefoxitin is a semisynthetic cephamycin with good in vitro activity against Neisseria gonorrhoeae. In a controlled clinical trial, 143 men with uncomplicated gonococcal urethritis received either cefoxitin (2.0 g intramuscularly [im] with 1.0 g of oral probenecid) or aqueous procaine penicillin G (4.8 x 10(6) units im….
Mesima · 2003 · Journal Article · Biotechnology letters
Extracts of Phellinus linteus grown on germinated brown rice suppress liver damage induced by carbon tetrachloride in rats
Extracts of Phellinus linteus (EPB), grown on germinated brown rice, protected rats from liver injury induced by carbon tetrachloride (CCl₄). Peroxidation products in the liver were decreased to 10% by EPB..
Lion's Mane · 2003 · Research Article · Jun wu xi tong = Mycosystema
Observation of chlamydospores produced form Hericium erinaceus monocaryotic mycelium
A plastic tissue adhesive, trifluoroisopropyl 2-cyanoacrylate (Flucrylate (TM), MBR4197), was tested for hemostatic efficacy in acute laparotomy experiments using a canine model of acute bleeding gastric ulcer. An improved delivery system suitable for endoscopic use was developed..
Lion's Mane · 2002 · Journal Article · Acta Agriculturae Universitatis Jiangxiensis
A Preliminary Study on the Selection of Hericium erinaceus Strain Ninghou No.6
Approximately one-third of the cells in the liver are nonhepatocytes. Of these, the Kupffer cells, or phagocytes lining the sinusoids, are of particular significance since environmental carcinogens must first traverse a Kupffer cell barrier before reaching the liver parenchyma..
Snow Fungus · 2002 · Journal Article · Journal of agricultural and food chemistry
Interactions of lipid metabolism and intestinal physiology with Tremella fuciformis Berk edible mushroom in rats fed a high-cholesterol diet with or without Nebacitin.
Male adult Wistar rats were randomly divided into six groups in a 2 x 3 factorial design and fed diets containing different levels of Tremella fuciformis Berk (TFB) dietary fiber (0, 5, or 10%) and 1 g of cholesterol/100 g of diet with or without 0.7% Nebacitin for 4 weeks..
Wood Ear · 1998 · Journal Article · Bioscience, biotechnology, and biochemistry
Hypoglycemic Effect of Water-soluble Polysaccharide from Auricularia auricula-judae Quel. on Genetically Diabetic KK-Ay Mice
The hypoglycemic effect of water-soluble polysaccharide(FA) from fruiting bodies of Auricularia auricula-judae Quel. was investigated on genetically diabetic mice (KK-Ay) from 10 to 14 weeks of age..
Enoki · 1998 · Journal Article · Chinese Journal of Anatomy
Inhibitory activity of polysaccharides from bodies of Flammulina velutipes Sing on proliferation of human hepatoma SMMC-7721 cells
Result of rubella haemagglutination inhibition antibody test on 300 Thai women of childbearing age in upper socioeconomic group showed that 25% were susceptible to rubella. The high frequency of susceptibility in this group of women would be of considerable public health problem, should rubella become epidemic again..
Enoki · 1998 · Journal Article · Food and Fermentation Industries
Studies on submerged fermentation process of Flammulina velutipes FV088
Factor VIII procoagulant activity (VIII-C), related antigen (VIII-AG), and von Willebrand factor (VIII-vWf) were measured in 38 patients with chronic renal failure (CRF), in 19 patients with normal renal function from a general medical ward, and in 17 normal subjects..
Zhu Ling · 1994 · Journal Article · The American journal of Chinese medicine
Combined effects of chuling (Polyporus umbellatus) extract and mitomycin C on experimental liver cancer.
Chuling (Polyporus umbellatus), one of the commonly used Chinese medical herbs, was combined with mitomycin C and then studied against intrahepatic implantation of sarcoma 180 tumor cells in mice..
Zhu Ling · 1991 · Journal Article · Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine
[Effect of Polyporus umbellatus polysaccharide on function of macrophages in the peritoneal cavities of mice with liver lesions].
The cells in peritoneal cavities of mice were taken out and cultured in vitro. The amount to release H2O2 of the macrophages was assayed by fluorimetry.
Cordyceps · 2026 · Research Article · Pharmaceutics
A Green Self-Assembled Nanoplatform of 10-Hydroxycamptothecin and Cordyceps Polysaccharides for Dual Anti-Tumor Efficacy Through Apoptosis and Immune Modulation.
Background: Melanoma is one of the most dangerous types of skin cancer, with its global incidence having surged in recent years. There exists an urgent clinical need for novel therapeutic strategies that combine high efficacy, low toxicity, and multiple mechanisms of action..
Turkey Tail · 2025 · Journal Article · Journal of functional foods
Anti-inflammatory and immunomodulatory effects in vitro of polysaccharide- and polyphenol-rich extracts of white button and Turkey Tail mushrooms
The health-promoting properties of mushrooms are associated with bioactive natural compounds such as polysaccharides and polyphenols. Anti-inflammatory and immunomodulatory properties of edible white button mushroom (WBM) and medicinal Turkey Tail mushroom (TT) were investigated..
Shiitake · 2025 · Research Article · Food chemistry: X
Preparation of soybean oil-based emulsions stabilized by shiitake mushroom chitosan modified in both enzymatic and non-enzymatic systems and their application in β-carotene delivery.
This study investigates the laccase-catalyzed grafting of gallic acid (GA) onto shiitake mushroom chitosan to enhance its emulsifying properties and improve β-carotene delivery..
Cordyceps · 2025 · Research Article · Frontiers in medicine
Preventing metabolic-associated fatty liver disease with fermented cordyceps preparation: an electronic medical record based study.
BACKGROUND: Metabolic-associated fatty liver disease (MAFLD) is a prevalent chronic liver condition with significant health implications. Fermented Cordyceps Preparation (FCP) has shown promise in managing metabolic disorders, prompting interest in its potential for MAFLD prevention..
Cordyceps · 2024 · Journal Article · Archives of microbiology
A rho-type GTPase activating protein affects the growth and development of Cordyceps cicadae.
Cordyceps cicadae is recognized for its medicinal properties, attributed to bioactive constituents like polysaccharides and adenosine, which have been shown to improve kidney and liver functions and possess anti-tumor properties..
Oyster Mushroom · 2024 · Journal Article · Food & function
Novel approach for ameliorating high-fat diet-induced syndromes via probiotic-fermented oyster mushroom: from metabolites and microbiota to regulation mechanisms.
The potential effects of probiotics on lowering lipid accumulation and alleviating gut microbiota perturbation have been extensively substantiated, but whether Lactobacillus rhamnoses-fermented oyster mushroom (FOM) could more pronouncedly attenuate obesity remains unclear..
Cordyceps · 2024 · Journal Article · International journal of biological macromolecules
The "crosstalk" between gut microbiota, metabolites and genes in diet-induced hepatic steatosis mice intervened with Cordyceps guangdongensis polysaccharides.
Cordyceps guangdongensis, a novel edible mushroom in China, has shown many positive health effects. In this study, we extracted the C.
Maitake · 2017 · Research Article · PloS one
Antitumor activity of orally administered maitake α-glucan by stimulating antitumor immune response in murine tumor.
Maitake α-glucan, YM-2A, isolated from Grifola frondosa, has been characterized as a highly α-1,6-branched α-1,4 glucan. YM-2A has been shown to possess an anti-virus effect in mice; however, it does not directly inhibit growth of the virus in vitro, indicating that the anti-virus effect of YM-2A might be associated….
Shiitake · 2026 · Review · Colloids and surfaces. B, Biointerfaces
Comprehensive mechanisms and advanced delivery strategies of lentinan in antitumor therapy: A review.
Lentinan (LNT) is a bioactive polysaccharide derived from shiitake mushrooms (Lentinula edodes). It exhibits a unique triple-helix structure and specific glycosidic bonds, which confer exceptional water solubility and gel-forming properties..
Cordyceps · 2025 · Review · International journal of medicinal mushrooms
The Role of Medicinal Mushrooms in Cancer Treatment: Bioactive Compounds and Therapeutic Potential.
In recent years, research on the therapeutic potential of mushroom species has notably expanded, and the effects of these organisms on cancer treatment have come to the forefront..
Reishi · 2023 · Abstract · Journal of animal science
202 Functional Properties of Ganoderma Lucidum (GL) Supplementation in Canine Nutrition
Metadata-grounded summary: This abstract indexes research on Ganoderma lucidum in Journal of animal science in 2023. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..
Oyster Mushroom · 2023 · Published Erratum · AMB Express
Correction: Anti-tumor effect of polysaccharide from Pleurotus ostreatus on H22 mouse Hepatoma ascites in-vivo and hepatocellular carcinoma in-vitro model.
Metadata-grounded summary: This published erratum indexes research on Pleurotus ostreatus in AMB Express in 2023. MycoData maps the paper to oncology, immune support, liver support based on its title, species context, article metadata, and study classification..
Niu-Chang-Chih · 2022 · Research Support, Non U.S. Gov'T · Aging
Antrodia Camphorata Polysaccharide activates autophagy and regulates NLRP3 degradation to improve liver injury-related inflammatory response.
This study illustrated the liver protection mechanism of ACP from the perspective of autophagy activation. ACP suppressed the inflammatory injury of KCs, and decreased the cell apoptosis rate..