MycoData

Bletilla striata, a traditional Chinese medicinal herb, is particularly rich in phenanthrenes and their dimers, which exhibit anti-inflammatory, antibacterial, and antitumor properties..

OncologyImmune support

Medium relevance

Enoki · 2026 · Research Article · Journal of fungi (Basel, Switzerland)

Mating-Type Imputation (MTI) Provides an Efficient Tool for the Mating-Type Inference of Tetrapolar Fungi.

Mating-type identification is fundamental to studies of genetic diversity and genetic breeding in fungi, especially for tetrapolar basidiomycetes, whose mating types are determined by two multiallelic loci, A and B..

Medium relevance

Turkey Tail · 2026 · Journal Article · Journal of hazardous materials

Mechanistic insights into the enhancement of azithromycin biodegradation by extracellular polymeric substances: Roles of metabolic activity, electron transfer, and reactive oxygen species.

White-rot fungi (WRF) have shown potential as an effective alternative for antibiotic removal in wastewater treatment. However, their slow degradation rates remain a major challenge..

Energy & fatigueMetabolic health

Medium relevance

Shiitake · 2026 · Journal Article · Ecotoxicology and environmental safety

Metal-organic framework-hybridized immobilized laccase for the efficient degradation of industrial wastewater pollutants.

Natural laccases from Lentinula edodes exhibit remarkable catalytic versatility in degrading various organic pollutants in industrial wastewater. However, their practical applications are limited by their inherent structural instability and poor reusability..

Energy & fatigue

Medium relevance

Oyster Mushroom · 2026 · Journal Article · Methods in molecular biology (Clifton, N.J.)

Microalgae Harvesting Using Fungal Mycelia in Suspension.

Fungi can be used to flocculate and harvest microalgae at a high efficiency in a more resource- and cost-efficient, and sustainable manner than traditional microalgal harvesting methods. However, the two most common fungal-assisted microalgal harvesting methods are lengthy..

Medium relevance

Turkey Tail · 2026 · Journal Article · Bioresource technology

Molecular orbital-guided design of laccase-mediator systems for antibiotic removal in the presence of humic acid.

Antibiotic residues, as emerging environmental contaminants, have raised significant concerns, underscoring the urgent need for efficient laccase-mediator systems (LMS) to facilitate their removal..

Energy & fatigue

Medium relevance

Shiitake · 2026 · Journal Article · Food Research International

Molecular weight-engineered lentinan fractions as prebiotic modulators: Steering gut microbiota for precision obesity intervention

Lentinus edodes polysaccharides are widely recognized for their potential contributions to human health, in part due to their interactions with the gut microbiota..

Immune supportGut & microbiome

Medium relevance

Shiitake · 2026 · Journal Article · Food research international (Ottawa, Ont.)

Molecular weight-engineered lentinan fractions as prebiotic modulators: Steering gut microbiota for precision obesity intervention.

Lentinus edodes polysaccharides are widely recognized for their potential contributions to human health, in part due to their interactions with the gut microbiota..

Immune supportGut & microbiome

Medium relevance

Reishi · 2026 · Research Article · Frontiers in pharmacology

Multi-omics integration identifies ganoderic acid A as a TNFα inhibitor for treating sepsis-related liver injury.

Ganoderic acid A (GAA), a major bioactive triterpenoid from Ganoderma lucidum, is known for its anti-inflammatory effects; however, its precise molecular targets in sepsis-related liver injury (SRLI) remain unclear..

OncologyImmune supportLiver support

Medium relevance

Lion's Mane · 2026 · Journal Article · International journal of biological macromolecules

Multiscale interaction of Hericium coralloides polysaccharide with maize starch: Impact on structural properties and digestibility.

Regulating starch digestion to alleviate postprandial hyperglycemia is one of the core challenges in the field of nutrition. Edible mushroom polysaccharides have become highly promising natural starch modifiers due to their dual functions of modulating food structure and potentially inhibiting digestive enzyme….

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Medium relevance

Enoki · 2026 · Journal Article · ACS synthetic biology

Mushroom Derived STS-HMGS Fusion Enzyme Enhances Sesquiterpene Production in Fungal Hosts.

3-Hydroxy-3-methylglutaryl-CoA synthase (HMGS) is a key enzyme in the mevalonate (MVA) pathway that catalyzes the formation of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) from acetoacetyl-CoA and acetyl-CoA. Recently, a novel class of HMGS-sesquiterpene synthase (STS) fusion enzymes has been identified..

Energy & fatigueMetabolic health

Medium relevance

Snow Fungus · 2026 · Journal Article · Carbohydrate polymers

Naturally derived polysaccharides and ganoderic acid A hydrogel with whitening potential to combat oxidative stress and melanin production caused by ultraviolet B

The intersection of natural products and precision skin care has become a new trend in cosmetic development. This study developed a hydrogel composed of oxidized Tremella fuciformis polysaccharide, carboxymethyl chitosan, and Ganoderic acid A..

Immune supportSkin & hydration

Medium relevance

Snow Fungus · 2026 · Journal Article · Carbohydrate polymers

Naturally derived polysaccharides and ganoderic acid A hydrogel with whitening potential to combat oxidative stress and melanin production caused by ultraviolet B.

Immune supportSkin & hydration

Medium relevance

Yellow Morel · 2026 · Journal Article · Molecular diversity

Novel oleanolic acid derivatives containing piperazine pyrimidine moieties: design, synthesis, and antimicrobial activity.

Natural products are main sources of new chemical entities for pesticide discovery and also important modification substrates for activity enhancement. In this study, a series of novel oleanolic acid derivatives containing piperazine pyrimidine structures were designed and synthesized..

Energy & fatigue

Medium relevance

Cordyceps · 2026 · Journal Article · Applied biochemistry and biotechnology

Ophiocordyceps indica from the Indian Himalayas Ameliorates the IgA Nephropathy in Mice.

Immunoglobulin A nephropathy (IgAN) is the most common form of chronic glomerulonephritis and a major cause of end-stage renal disease worldwide, currently lacks safe, effective therapies. Ophiocordyceps sinensis, a well-known traditional medicinal fungus and used for treating kidney-related disorders..

OncologyImmune support

Medium relevance

Turkey Tail · 2026 · Journal Article · BMC immunology

Polypore mushroom mycelia as an adjunct to COVID-19 vaccination: a randomized clinical trial.

BACKGROUND: Use of fungal mycelium as a vaccination adjunct may constitute a novel antiviral strategy to address newly emerging viruses. We evaluated safety and feasibility of a fungal mycelium-based natural product (Fomitopsis officinalis and Trametes versicolor, FoTv) as an adjunct to human COVID-19 vaccination, as….

Immune supportLiver supportRespiratory

Medium relevance

Turkey Tail · 2026 · Research Article · International journal of molecular sciences

Rational Design of Mn-APTES/1-Methylimidazole Nanozymes: Enhanced Laccase-like Activity at Near-Neutral pH for Environmental Remediation.

Natural laccases are a widely reported option for pollutant degradation; however, their widespread application is severely restricted by high production costs, limited storage stability, and rapid inactivation at the neutral pH typical of wastewater treatment plants..

Medium relevance

Zhu Ling · 2026 · Journal Article · Cellular and molecular life sciences: CMLS

Renal fibrosis is induced by hyperactive Wnt/β-catenin pathway via microbial-mediated tryptophan metabolism-driven AhR signaling in rodents and humans.

Renal fibrosis is a common pathological endpoint in progressive chronic kidney disease (CKD). Clinical evidence indicates that a decline in renal function is more closely associated with tubulointerstitial fibrosis (TIF) than with glomerular injury..

Energy & fatigueMetabolic healthGut & microbiome

Medium relevance

Oyster Mushroom · 2026 · Research Article · Aquaculture nutrition

Species- and Level-Dependent Modulation of Growth and Skin and Intestinal Mucosal Microbiota in Rainbow Trout Fed Mushroom Stem Meals.

Mucosal microbiomes play key roles in fish physiology by supporting digestion, nutrient absorption, metabolism, immune modulation, and pathogen defense. This study evaluated the effects of mushroom stem meals from Agaricus bisporus (AB) and Pleurotus ostreatus (PO) as nutritional alternatives to soybean meal (SBM) on….

Immune supportEnergy & fatigueGut & microbiomeSkin & hydration

Medium relevance

Snow Fungus · 2026 · Research Article · Molecules (Basel, Switzerland)

Structural Elucidation and Moisturizing Potential of a Polysaccharide Derived from Tremella mesenterica.

Tremella mesenterica, commonly known as the yellow brain or golden jelly fungus, has been traditionally used for its medicinal properties. In this study, we elucidated the structural characteristics of T..

Immune supportCognition & nervesMetabolic healthSkin & hydration

Medium relevance

Reishi · 2026 · Journal Article · Industrial crops and products

Synergistic interplay of deep eutectic solvents and multi-modal extraction techniques: A paradigm shift in natural polysaccharide yield, structural modulation, and biofunctional enhancement

Natural polysaccharides are essential macromolecules found in both plant and animal kingdoms, playing significant roles in food, medicine, biomaterials, and packaging. Deep eutectic solvents (DES), formed through hydrogen-bond interactions, offer simple synthesis, eco-friendliness, and lower melting points..

Immune supportMetabolic health

Medium relevance

Turkey Tail · 2026 · Journal Article · Bioorganic & medicinal chemistry

Synthesis and biological evaluation of novel C1 or C3 amino derivatives of A-ring 1,2,3-trisubstituted 19-nor-vitamin D3.

Two new analogs of 1α,25-dihydroxy-19-nor-vitamin D3 with an additional hydroxyl group at position 2 and an amino group at C1 or C3 using quinic acid as starting substrate for the A-ring precursor are described..

Oncology

Medium relevance

Reishi · 2026 · Journal Article · International journal of biological macromolecules

Targeting HSP90 destabilization with ganoderic acid a as a novel therapeutic strategy for hepatoblastoma.

BACKGROUND: Hepatoblastoma (HB) is the most prevalent primary liver malignancy in children and is characterized by aggressive progression and suboptimal therapeutic outcomes..

OncologyLiver support

Medium relevance

Shiitake · 2026 · Journal Article · International journal of biological macromolecules

The BraBRI1-BraBZR1/BraBES1 module regulates proteoglycan- and brassinosteroid-induced thermotolerance in Pakchoi.

As a globally cultivated leafy vegetable and an important economic crop, the production of Pakchoi (Brassica rapa ssp. chinensis var.

Medium relevance

Shiitake · 2026 · Journal Article · Phytopathology

The Host Range and Pathogenic Potential Differences Between Aphelenchoides oryzae and Aphelenchoides pseudobesseyi.

Foliar nematodes within the Aphelenchoides besseyi species complex are economically important plant parasites. Unfortunately, the species delimitation and their host range have been unclear because these nematodes were long considered a single species.

Energy & fatigue

Medium relevance

Oyster Mushroom · 2026 · Journal Article · Pharmaceuticals (Basel, Switzerland)

The Use of Biomass from In Vitro Fungal Cultures as a Bioactive Ingredient with Antimicrobial Activity in Hydrogel Dressings.

Background/Objectives: Chronic wounds represent a significant clinical burden and require multimodal treatment strategies targeting inflammation, infection, moisture balance, and tissue remodeling, as defined by the TIME framework..

Immune supportEnergy & fatigueSkin & hydration

Medium relevance

Snow Fungus · 2026 · Research Article · Regenerative biomaterials

Three-dimensional-printed ROS-scavenging and immunomodulatory hydrogel accelerates diabetic wound healing through synergistic microenvironment regulation.

The management of diabetic wounds remains clinically challenging, primarily owing to three interrelated pathological mechanisms: excessive accumulation of reactive oxygen species (ROS), dysregulated angiogenesis and sustained, non-resolving inflammation..

Immune supportEnergy & fatigueMetabolic healthSkin & hydration

Medium relevance

Oyster Mushroom · 2026 · Research Article · International journal of environmental research and public health

Toxicological Assessment of 17β-Estradiol and 17α-Ethinylestradiol After Adsorption in a Biomass Filter Associated with the Nanomaterial δ-FeOOH.

Emerging contaminants pose significant risks to ecosystems yet are not routinely included in standard monitoring or regulatory frameworks. Among these substances, endocrine disruptors such as β-estradiol and 17α-ethinylestradiol threaten both human and environmental health by interfering with metabolism, reproduction,….

Medium relevance

Oyster Mushroom · 2026 · Journal Article · Food Hydrocolloids

Unconventional chitosan from mushroom by-products as an alternative fining agent for white wines stabilization

Protein haze in white wines, conventionally managed with bentonite, poses significant drawbacks. Since bentonite fining is associated with wine losses, colour and aroma depletion, and environmental concerns, sustainable alternative are needed..

Medium relevance

Turkey Tail · 2026 · Journal Article · Scientific reports

Valorisation of waste OSB into sustainable mycelium-based composites for insulation applications.

The need for the construction industry to reduce its contribution to landfill waste and greenhouse gas emissions is urgent, with engineered wood products such as oriented strand board (OSB) representing a complex and difficult-to-recycle waste stream..

Energy & fatigueGut & microbiome

Medium relevance

Turkey Tail · 2026 · Research Article · Polymers

Walls That Grow: Fungal Species-Driven Performance of Mycelium-Based Composites Grown on Rice-Husk Waste.

Mycelium-based composites (MBCs) are gaining attention as sustainable alternatives to conventional materials because they are grown biologically rather than produced through resource-intensive extraction and processing..

Energy & fatigue

Medium relevance

Turkey Tail · 2025 · Research Article · Molecules (Basel, Switzerland)

A New Lignin-Based Polyurethane Film for Wood: Decay, Artificial Weathering, Physical and Morphological Characterization.

Lignin-based polyurethanes represent a promising strategy for developing more sustainable wood coatings by partially replacing fossil-derived polyols with renewable aromatic biopolymers..

Medium relevance

Reishi · 2025 · Research Article · Frontiers in chemistry

A rapid approach for discriminating Ganoderma species using attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy integrated with chemometric analysis and convolutional neural network (CNN).

The issue of adulteration and misclassification of Ganoderma species is addressed in this research. In the study, we present a novel and comprehensive framework for Ganoderma authentication by analyzing attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectra using a combined approach of a….

Cognition & nerves

Medium relevance

Agarikon · 2025 · Journal Article · International journal of biological macromolecules

A TME-responsive polysaccharide nanoplatform integrating synergetic therapy for cancer.

A self-assembling nanoplatform based on FOB (a heteropolysaccharide from Fomitopsis officinalis) named QU@FOB-FcDBA was developed in this study. A dynamic boronate ester bond, a pH-sensitive covalent linkage formed through reversible dehydration reactions, linked FOB and 1,1'-ferrocenediboronic acid (FcDBA) while….

OncologyImmune supportCognition & nervesEnergy & fatigue

Medium relevance

Reishi · 2025 · Journal Article · Eur J Plant Pathol

Action of fungal filtrates on alternaria linariae and on development of tomato early blight

The adaptability of tomato (Solanum lycopersicum L.) to soil characteristics and climate is one of the main factors that led to its large-scale cultivation. However, wide scale cultivation also contributes to the emergence of phytosanitary problems, like pathogens such as Alternaria spp., the pathogen causing early….

Medium relevance

Reishi · 2025 · Research Article · Foods (Basel, Switzerland)

Alterations in Functional Constituents and Bioactivities of Tartary Buckwheat via Solid-State Fermentation with Three Edible-Medicinal Fungi: A Metabolomics-Based Analysis.

To functionally enhance Tartary buckwheat and elucidate the underlying mechanisms of change, solid-state fermentation (SSF) was conducted using three edible-medicinal fungi-Auricularia auricula (A. auricula), Ganoderma lucidum (G.

Metabolic health

Medium relevance

Turkey Tail · 2025 · Journal Article · International journal of medicinal mushrooms

Analysis of Antioxidant and Anticancer Activities of Selected Trametes Species (Agaricomycetes) from Iran.

The remarkable spectrum of bioactive compounds in medicinal mushrooms makes them an excellent source for treating a variety of diseases. Among these, Trametes Fr.

OncologyImmune supportMetabolic health

Medium relevance

Oyster Mushroom · 2025 · Research Article · Nanomaterials (Basel, Switzerland)

Analysis of the Development and Thermal Properties of Chitosan Nanoparticle-Treated Palm Oil: An Experimental Investigation.

This study is an effort to optimize the thermal properties of refined, bleached, and deodorized (RBD) oil by incorporating bionanoparticles. This study investigates the impact on thermal conductivity and thermal diffusivity by incorporating chitosan nanoparticles (CS-NPs) at different temperatures with varying weight….

Medium relevance

Maitake · 2025 · Journal Article · Journal of agricultural and food chemistry

Antihypertension and Improvement Effects of Hexapeptide APPLRP on Exosomes-Mediated Vascular Endothelial Inflammation in Spontaneously Hypertensive Rats.

The hexapeptide APPLRP from the edible Grifola frondosa mushroom has been verified to possess significant ACE inhibitory activity and ameliorates vascular remodeling. However, in vivo effects have not been systematically investigated..

Immune supportMetabolic healthSkin & hydration

Medium relevance

Mesima · 2025 · Journal Article · International journal of medicinal mushrooms

Antioxidant Activity and Total Terpenoid Content of Tropicoporus linteus Cultivar (Agaricomycetes) Cold Water Extract and In Silico Assessment of Potential Neuroprotective Compounds.

Tropicoporus linteus (formerly Phellinus linteus) is a medicinal fungus used in China, Korea and Japan for its therapeutic properties. This study assessed the antioxidant capabilities of cold-water extract (xSHTM) from a T.

Cognition & nervesGut & microbiome

Medium relevance

Reishi · 2025 · Journal Article · International journal of molecular sciences

Antrodia cinnamomea Formula Suppresses Prostate Cancer Progression via Immune Modulation and PD-1/PD-L1 Pathway Inhibition.

Prostate cancer remains a significant global health challenge, necessitating the development of novel therapeutic approaches. This study investigated the therapeutic potential of the Antrodia cinnamomea formula (XIANZHIFANG formula, XZF), comprising Antrodia cinnamomea, Sanghuangporus sanghuang, Ganoderma lucidum,….

OncologyImmune support

Medium relevance

Niu-Chang-Chih · 2025 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Antroquinonol mitigates Tau hyperphosphorylation, neuronal damage and cognitive impairments in a chronic cerebral ischemia rat model.

Chronic cerebral ischemia (CCI) induced hyperphosphorylated Tau has been associated with an increased risk of neurodegenerative disorders such as Alzheimer's and vascular dementia..

OncologyImmune supportCognition & nervesMetabolic health

Medium relevance

Niu-Chang-Chih · 2025 · Research Article · Frontiers in nutrition

Antroquinonol reduces IL-1β production in macrophages through enhancing the DNA methylation of Tlr4.

INTRODUCTION: Macrophages represent one of the most pivotal immune cells in the innate immune responses of weaned piglets. Emerging studies have revealed that numerous plant- or fungal-derived extracts significantly modulate macrophage functions..

Immune support

Medium relevance

Oyster Mushroom · 2025 · Journal Article · Journal of hazardous materials

Assessment of nicotine and degradation products in cigarette butts leachates after detoxification by white rot fungi.

Cigarette butts (CBs) are widespread hazardous waste contaminating the environment due to the recalcitrance of the filter and the toxicity of the contaminants leached..

Medium relevance

Turkey Tail · 2025 · Journal Article · Science of the Total Environment

Barriers and guidelines in the use of fungi in pesticide bioremediation: A global overview

The increasing use of synthetic pesticides, driven by global food demand, highlights the need for effective environmental decontamination strategies. Bioremediation represents a sustainable approach, with fungi showing potential due to their unique metabolic capabilities..

Metabolic health

Medium relevance

Turkey Tail · 2025 · Research Article · Biomimetics (Basel, Switzerland)

Binder Jetting 3D Printing of Biomass-Fungi Composite Materials: A Preliminary Experimental Study.

This paper reports on a preliminary experimental study on binder jetting 3D printing of biomass-fungi composite materials. Biomass-fungi composite materials have potential applications in the packaging, furniture, and construction industries..

Medium relevance

Reishi · 2025 · Journal Article · Natural product research

Bioactive secondary metabolites from an endophytic fungus Chloridium virescens GLQ05 and structural revision of alteamide.

Two previously undescribed metabolites, chlovirescenols A (1) and B (5), along with six known compounds including amides (2-4), macrolides (6 and 8), meroterpenoid (7), were obtained from the Ganoderma lucidum-derived endophyte Chloridium virescens GLQ05..

Immune support

Medium relevance

Oyster Mushroom · 2025 · Research Article · Toxins

Biocatalytic Detoxification of Ochratoxins A/B by a Fungal Dye-Decolorizing Peroxidase: Mechanistic Insights and Toxicity Assessment.

Mycotoxin contamination in agricultural products poses severe global health risks, with ochratoxins (particularly OTA and OTB) exhibiting marked nephrotoxicity and classified as Group 2B carcinogens by IARC..

Oncology

Medium relevance

Reishi · 2025 · Research Article · Current issues in molecular biology

Biomarker Discovery and Molecular Docking Reveal Marsdenia tenacissima Fermentation Product's Anti-Lung Cancer Components.

In traditional Chinese medicine, Marsdenia tenacissima is employed to prevent and treat lung cancer. The anti-tumor properties are further amplified by the fermentation product of Ganoderma lucidum and Marsdenia tenacissima (MGF)..

OncologyRespiratory

Medium relevance

Turkey Tail · 2025 · Research Article · ChemistryOpen

Biosensor Based on the Immobilization of Laccase on β-Cyclodextrin Membrane for the Evaluation of Antioxidant Capacity in Real Samples.

The optimization of a new amperometric biosensor for evaluating antioxidant capacity in real samples is reported. The biosensor is based on the immobilization of Laccase from Trametes versicolor on an electropolymerized β-cyclodextrin polymeric membrane on a glassy carbon electrode..

Energy & fatigue