MycoData

This study systematically investigated the decolorization efficacy and detoxification effect of crude laccase derived from Pleurotus ostreatus yang1 on azo and triphenylmethane dyes..

Energy & fatigue

High relevance

Oyster Mushroom · 2025 · Research Article · Scientific reports

Effect of acid modification of Biochar derived from spent mushroom substrate on the production of oyster mushroom (Pleurotus ostreatus).

Spent mushroom substrate (SMS) disposal presents significant environmental challenges in the edible fungi industry. Converting SMS into biochar offers a promising resource utilization approach; however, the original biochar properties limit its effectiveness in mushroom cultivation applications..

Energy & fatigue

High relevance

Cordyceps · 2025 · Research Article · FEBS open bio

Effect of Cordyceps militaris extract containing cordycepin on the adipogenesis and lipolysis of adipocytes.

Obesity, a global health concern, results from an energy imbalance leading to lipid accumulation. In the present study, Cordyceps militaris extract (CM) and its primary component, cordycepin, were investigated to characterize their potential effects on adipogenesis and lipolysis..

Energy & fatigueMetabolic health

High relevance

Cordyceps · 2025 · Research Article · Animal bioscience

Effects of Cordyceps militaris solid medium on the growth performance, immunity parameters and intestinal health of broilers.

OBJECTIVE: This study aimed to investigate the impact of Cordyceps militaris solid medium (CMM) on the growth performance, immunity parameters, intestinal health and gut microbiota of broilers..

Immune supportEnergy & fatigueGut & microbiome

High relevance

Oyster Mushroom · 2025 · Journal Article · Journal of applied poultry research

Effects of dietary inclusion of oyster mushroom (Pleurotus ostreatus) powder on live performance, physical meat quality, hemato-biochemical indices and cecal bacterial load in Sonali chickens

The current research aimed to assess the effects of oyster mushroom powder as potential alternative to antibiotic growth promoters on growth performance, physical meat quality, hemato-biochemical indices and cecal bacterial load in Sonali chickens..

Energy & fatigueMetabolic healthGut & microbiome

High relevance

Chaga · 2025 · Journal Article · Meat science

Effects of dietary Inonotus obliquus fermentation products supplementation on meat quality and antioxidant capacity of finishing pigs

This study aimed to investigate the supplementation of finishing pigs with Inonotus obliquus fermentation products (IOFP) on the meat quality, amino acid and fatty acid composition, muscle fiber characteristics, and antioxidant capacity..

Energy & fatigue

High relevance

Chaga · 2025 · Journal Article · Meat science

Effects of dietary Inonotus obliquus fermentation products supplementation on meat quality and antioxidant capacity of finishing pigs.

Energy & fatigue

High relevance

Oyster Mushroom · 2025 · Journal Article · Innovative Food Science and Emerging Technologies

Enhanced extraction of Pleurotus ostreatus polysaccharides via plasma-ultrasound synergy: Kinetics modeling and functional characterization

The limitations of traditional extraction methods in terms of efficiency and environmental sustainability have highlighted the urgent need for advancements in extraction technology..

Immune supportEnergy & fatigue

High relevance

Reishi · 2025 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Enhancement of grindability and physicochemical properties of Ganoderma lucidum through steam explosion and its impact on quality characteristics of wheat dough

Steam explosion (SE) was applied to enhance the grinding performance and physicochemical properties of Ganoderma lucidum (GL), and the effects of steam-exploded Ganoderma lucidum powders (SGL) on quality characteristics of wheat dough were investigated..

Immune supportEnergy & fatigueSkin & hydration

High relevance

Oyster Mushroom · 2025 · Research Article · BMC plant biology

Enhancing Pearl oyster mushroom (Pleurotus ostreatus (Jacq.) P. Kumm) performance by evaluating the influence of potassium humate and wheat straw on yield and biochemical attributes.

This study investigated the effects of various combinations of potassium humate and raw wheat straw (RWS) treatments on the growth, yield, and quality of Pleurotus ostreatus (Jacq.) P. Kumm across two growing seasons..

Energy & fatigue

High relevance

Reishi · 2025 · Review · International journal of biological macromolecules

Extraction, purification, structural characterization, biological activity, mechanism of action and application of polysaccharides from Ganoderma lucidum: A review.

Ganoderma lucidum is a traditional tonic medicine in China, known as the "fairy grass" and "spiritual grass". It contains various chemical components, such as polysaccharides, triterpenoids, alkaloids, nucleosides, sterols, and acid compounds, which have the effects of tonifying qi and calming the mind, stopping cough….

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Enoki · 2025 · Research Article · Journal of dental sciences

Flammulina velutipes polysaccharides exhibit potent antioxidant and anti-pyroptotic properties in diabetes-associated periodontitis: A preliminary in vitro study.

BACKGROUND/PURPOSE: Diabetes-associated periodontitis (DAP) is a complicated illness characterized by elevated oxidative stress and a pro-inflammatory response. There is a bidirectional relationship between diabetes and periodontitis..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Cordyceps · 2025 · Journal Article · Journal of agricultural and food chemistry

Functional Characterization of a β-1,3-Glucanosyltransferase CmGel4 in Cordyceps militaris Using a Precise CRISPR-Cas9 Genome-Editing System.

Cordyceps militaris polysaccharides, especially β-glucans, have presented significant antitumor, hypoglycemic, and immunomodulatory activities. However, the enzymes involved in the branching formation of C.

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Cordyceps · 2025 · Research Article · Journal of fungi (Basel, Switzerland)

Fusarium pseudonygamai Promotes Blastospore Transformation in Ophiocordyceps sinensis: Insights into Microbial Interaction and Key Mechanisms.

Chinese cordyceps, a highly valued traditional medicine, is formed when the fungal parasite Ophiocordyceps sinensis infects an underground caterpillar (Thitarodes). This interaction progresses slowly, as the larvae have a long developmental period and the fungus requires several months to complete its growth..

Energy & fatigueGut & microbiome

High relevance

Reishi · 2025 · Journal Article · Fitoterapia

Ganoderma lucidum extract reduces skin aging by reducing mitochondrial stress and controlling mitochondrial numbers.

Mitochondrial dysfunction is one of the important signs of cellular and even individual aging. Ganoderma lucidum is a common edible and medicinal mushroom, widely used as a functional food in Asia.

Energy & fatigueSkin & hydration

High relevance

Reishi · 2025 · Journal Article · Journal of advanced research

Ganoderma lucidum spore powder enhances IFN-α-mediated antiviral capacity of COVID-19 vaccine boosters revealed by single-cell multi-omics sequencing.

INTRODUCTION: Reduced vaccine efficacy may hinder stable herd immunity. Traditional natural medicinal ingredients, such as Ganoderma lucidum products, have shown potential as safe and effective adjuvants to improve vaccine efficacy..

Immune supportEnergy & fatigueRespiratory

High relevance

Reishi · 2025 · Research Article · mBio

GlSlt2 positively regulates GlMyb-mediated cellulose utilization in Ganoderma lucidum.

UNLABELLED: Fungal degradation of cellulose facilitates the sustainable harnessing of biosphere energy and carbon cycling. Ganoderma lucidum is one of the basidiomycetes with the largest number of hydrolytic enzymes in its genome.

Energy & fatigue

High relevance

Oyster Mushroom · 2025 · Review · Molecules (Basel, Switzerland)

Green Valorization Strategies of Pleurotus ostreatus and Its By-Products: A Critical Review of Emerging Technologies and Sustainable Applications.

Pleurotus ostreatus, commonly known as the oyster mushroom, is a widely cultivated edible mushroom characterized by its nutritional value and health benefits. However, its large-scale production generates significant amounts of agro-industrial by-products, such as stipes, residual mycelium, and spent mushroom….

Energy & fatigue

High relevance

King Oyster · 2025 · Journal Article · Animal science journal =

Growth Performance, Apparent Digestibility, Serum Indices, and Fecal Bacterial Community Diversity in Yanbian Cattle Fed Diets With Fermented Spent Mushroom Substrate From Pleurotus Eryngii Instead of Brewers Spent Grain

This experiment was to evaluate the effect of fermented spent mushroom substrate from Pleurotus eryngii (FSMPE) instead of brewers spent grain (BSG) on growth performance, apparent digestibility, serum indices, and fecal bacterial community of Yanbian cattle..

Energy & fatigueGut & microbiome

High relevance

King Oyster · 2025 · Journal Article · Animal science journal = Nihon chikusan Gakkaiho

Growth Performance, Apparent Digestibility, Serum Indices, and Fecal Bacterial Community Diversity in Yanbian Cattle Fed Diets With Fermented Spent Mushroom Substrate From Pleurotus Eryngii Instead of Brewers Spent Grain.

Energy & fatigueGut & microbiome

High relevance

King Oyster · 2025 · Journal Article · International journal of biological macromolecules

High internal phase Pickering emulsions stabilized by Pleurotus eryngii protein-polysaccharide conjugates.

In this work, Pleurotus eryngii protein-polysaccharide conjugates (PE-PPCs) were used as the only stabilizer for the preparation of high internal phase emulsions (HIPEs)..

Immune supportEnergy & fatigueSkin & hydration

High relevance

Almond Mushroom · 2025 · Research Article · Biomedicines

Immunomodulatory Effects of Multivitamin Complexes Containing Agaricus blazei in Patients Undergoing Curative Resection for Non-Small-Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Multicenter Pilot Trial.

Background/Objectives: Surgical resection of non-small-cell lung cancer (NSCLC) often results in temporary suppression of natural killer cell activity (NKA), potentially increasing the risk of recurrence..

OncologyImmune supportEnergy & fatigueRespiratory

High relevance

Cordyceps · 2025 · Journal Article · International journal of biological macromolecules

Impact of the sterol O-acyltransferase gene (Cmare2) on morphology and stability of the mushroom Cordyceps militaris.

Strain degeneration in mushroom cultivation can lead to significant commercial losses, yet the genetic factors remain elusive. This study identified the sterol O-acyltransferase gene, Cmare2, which is associated with colony sectorization in Cordyceps militaris, using a T-DNA insertion-mutant library..

Energy & fatigueGut & microbiome

High relevance

Oyster Mushroom · 2025 · Research Article · Current research in food science

Implications of Pleurotus ostreatus solid-state bioprocessing on the nutritional composition, protein structure, and anti-hypertensive and anti-inflammatory potential of local beans (Phaseolus vulgaris L.).

Improving snacks formulation to make them more nutritionally balanced can support healthy growth and development in children. Specifically, this approach can be beneficial for preventing obesity and promoting overall metabolic health..

Immune supportEnergy & fatigueMetabolic health

High relevance

Cordyceps · 2025 · Review · Foods (Basel, Switzerland)

Influence of Culture Conditions on Bioactive Compounds in Cordyceps militaris: A Comprehensive Review.

Cordyceps militaris (C. militaris) is a medicinal fungus renowned for its diverse therapeutic properties, largely attributed to bioactive compounds such as cordycepin, polysaccharides, adenosine, D-mannitol, carotenoids, and ergosterol..

Immune supportEnergy & fatigue

High relevance

King Oyster · 2025 · Research Article · BMC biotechnology

Influence of low-intensity artificial light on the fatty acid profile of the biotechnologically important culinary mushroom Pleurotus eryngii in vitro.

BACKGROUND: The problem of searching for environmentally friendly regulators of the biosynthetic activity of edible and medicinal mushrooms is crucial for creating highly effective biotechnologies. One such regulator is light..

Energy & fatigue

High relevance

Lion's Mane · 2025 · Research Article · Fungal biology and biotechnology

Influences of substrate and tissue type on erinacine production and biosynthetic gene expression in Hericium erinaceus.

BACKGROUND: Lion's mane (Hericium erinaceus) mycelium produces erinacines, a suite of cyathane diterpenoids with established neuroactivities. While H.

Cognition & nervesEnergy & fatigue

High relevance

Chaga · 2025 · Research Article · Animal microbiome

Inonotus obliquus fermentation product improves growth performance and meat quality probably through intestine and antioxidant capacity enhanced by gut microbes and metabolites regulation in rabbits.

BACKGROUND: Inonotus obliquus is a medicinal edible fungus that contains a variety of biologically active ingredients and has multiple physiological effects. When supplemented in avian diet, Inonotus obliquus has proved to be beneficial.

OncologyImmune supportCognition & nervesEnergy & fatigue

High relevance

Cordyceps · 2025 · Journal Article · Food Chemistry

Investigation of the solid-state fermentation of Astragalus membranaceus residue with Cordyceps militaris: effects on phenolic profile and in vitro neuroprotective activity

We developed a Cordyceps militaris-mediated solid-state fermentation (SSF) strategy to enhance phenolic antioxidants in Astragalus membranaceus residue (AR) and confer neuroprotective effects against oxidative stress..

Immune supportCognition & nervesEnergy & fatigue

High relevance

Cordyceps · 2025 · Journal Article · Food chemistry

Investigation of the solid-state fermentation of Astragalus membranaceus residue with Cordyceps militaris: effects on phenolic profile and in vitro neuroprotective activity.

Immune supportCognition & nervesEnergy & fatigue

High relevance

Cordyceps · 2025 · Research Article · BMC complementary medicine and therapies

Laboratory cultivated Cordyceps militaris modulates cockroach allergen-induced inflammation in keratinocytes and macrophages dual cell platforms.

BACKGROUND: Cordyceps militaris (CM) is noted for its anti-inflammatory properties and potential efficacy in treating allergic diseases. This research aimed to investigate the anti-inflammatory effect of ethanolic and aqueous extracts from laboratory-cultivated specific Cordyceps militaris on Per a 2-induced….

OncologyImmune supportEnergy & fatigueSkin & hydration

High relevance

Reishi · 2025 · Journal Article · International journal of medicinal mushrooms

Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Aqueous Extract Reverses Hypoxia Induced Redox Imbalance and Inflammatory Response in Rat Thymocytes.

Inflammatory diseases are associated with immune imbalances and the linkage between immune system and inflammatory mechanisms, particularly under hypoxia, is still incomprehensive..

Immune supportEnergy & fatigue

High relevance

Reishi · 2025 · Journal Article · International journal of medicinal mushrooms

Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Restores Redox Homeostasis and Modulates Myogenesis, Myostatin, and Muscle Atrophy Markers in Hypobaric Hypoxia Induced Muscle Loss in Rats.

The present study aimed to see the pharmacological effects of the aqueous extract of Ganoderma lucidum in amelioration of hypobaric hypoxia (HH) mediated muscle wastage..

Energy & fatigue

High relevance

Lion's Mane · 2025 · Review · Nutrients

Lion's Mane Mushroom (Hericium erinaceus): A Neuroprotective Fungus with Antioxidant, Anti-Inflammatory, and Antimicrobial Potential-A Narrative Review.

Hericium erinaceus, commonly known as lion's mane mushroom, has gained increasing scientific interest due to its rich composition of bioactive compounds and diverse health-promoting properties. This narrative review provides a comprehensive overview of the nutritional and therapeutic potential of H..

Immune supportCognition & nervesEnergy & fatigue

High relevance

Chaga · 2025 · Journal Article · Journal of ethnopharmacology

Mechanisms of Inonotus obliquus (Fr.) Pilát polysaccharides in ameliorating lipid-induced skeletal muscle insulin resistance via PI3K/AKT and AMPK/ACC1/CPT1 signaling pathways.

ETHNOPHARMACOLOGICAL RELEVANCE: Inonotus obliquus (Fr.) Pilát, a traditional medicinal fungi, has been used to treat diabetes in China and Russia since the 16th century..

Immune supportEnergy & fatigueMetabolic healthLiver support

High relevance

Chaga · 2025 · Journal Article · International journal of medicinal mushrooms

Mechanistic Study of Chaga Medicinal Mushroom Inonotus obliquus (Agaricomycetes) Phenolic Compounds in the Treatment of Liver Cancer: A Database and Simulation Approach.

Inonotus obliquus is a large fungus with high phenolic content that has demonstrated promising potential for the treatment of liver cancer. However, studies investigating its mechanism of action in the treatment of liver cancer are scarce..

OncologyEnergy & fatigueLiver support

High relevance

Cordyceps · 2025 · Journal Article · Data in Brief

Metabolomic data on molecular weight fractions of the cultivated fruiting body of Ophiocordyceps sinensis and their pharmacological effects on airway tissues

Ophiocordyceps sinensis is a medicinal mushroom that has been traditionally used for promoting respiratory health and addressing diverse therapeutic needs. The data in this article provides insights into the metabolic profile of the cultivated fruiting body of Ophiocordyceps sinensis (xOs™) across different molecular….

Energy & fatigueMetabolic healthRespiratory

High relevance

Reishi · 2025 · Research Article · Veterinary world

Microencapsulated Ganoderma lucidum extract improves antioxidant capacity, intestinal morphology, and nutrient digestibility in free-range laying hens under tropical conditions.

BACKGROUND AND AIM: Free-range laying hens raised under tropical climates are susceptible to heat stress (HS), which compromises intestinal integrity, nutrient absorption, and egg quality..

Energy & fatigueMetabolic healthGut & microbiome

High relevance

Reishi · 2025 · Journal Article · Journal of Ethnopharmacology

Network pharmacology combined with transcriptomics reveals that Ganoderma lucidum spore and Sanghuangporus vaninii compound extract exerts anti-colorectal cancer effects via CYP24A1-mediated VDR pathway and TERT-mediated Wnt signaling pathway

As traditional medicinal fungi, Ganoderma lucidum and Sanghuangporus vaninii are widely used in the treatment of tumor related diseases and cancer adjuvant therapy with potent anticancer effects. However, the anticancer effect and mechanism of action of their compound extract remain unclear..

OncologyEnergy & fatigue

High relevance

Reishi · 2025 · Journal Article · Journal of ethnopharmacology

Network pharmacology combined with transcriptomics reveals that Ganoderma lucidum spore and Sanghuangporus vaninii compound extract exerts anti-colorectal cancer effects via CYP24A1-mediated VDR pathway and TERT-mediated Wnt signaling pathway.

ETHNOPHARMACOLOGICAL RELEVANCE: As traditional medicinal fungi, Ganoderma lucidum and Sanghuangporus vaninii are widely used in the treatment of tumor related diseases and cancer adjuvant therapy with potent anticancer effects..

OncologyEnergy & fatigue

High relevance

Enoki · 2025 · Research Article · Nutrients

Neuroprotective and Neurotrophic Potential of Flammulina velutipes Extracts in Primary Hippocampal Neuronal Culture.

Flammulina velutipes (enoki mushroom) is a functional edible mushroom rich in antioxidants, polysaccharides, mycosterols, fiber, and minerals. Accumulating evidence highlights its therapeutic potential across diverse pathological contexts, including boosting cognitive function..

Immune supportCognition & nervesEnergy & fatigue

High relevance

Cordyceps · 2025 · Journal Article · International journal of biological macromolecules

New insights of rotenone targeting cordycepin synthetase 1-cordycepin synthetase 2-glyceraldehyde-3-phosphate dehydrogenase (Cns1-Cns2-GAPDH) triple complex to enhance cordycepin synthesis in Cordyceps militaris.

Cordycepin isolated from Cordyceps militaris is an adenosine analogue with various biological activities, and its synthesis is dependent on cordycepin synthetase 1 (Cns1) and cordycepin synthetase 2 (Cns2)..

Immune supportEnergy & fatigueMetabolic health

High relevance

Reishi · 2025 · Research Article · Frontiers in chemistry

Non-destructive analysis of Ganoderma lucidum composition using hyperspectral imaging and machine learning.

BACKGROUND: Ganoderma lucidum is a widely used medicinal fungus whose quality is influenced by various factors, making traditional chemical detection methods complex and economically challenging..

Immune supportCognition & nervesEnergy & fatigue

High relevance

Shiitake · 2025 · Journal Article · Journal of agricultural and food chemistry

Novel Umami Peptides from Lentinula edodes: Evaluation of the Umami Enhancing Effect Using Biosensors and Molecular Simulation.

Lentinula edodes are edible fungi with a unique aroma and umami flavor. The current study sought to identify novel umami peptides in Lentinula edodes while investigating their umami-enhancing properties..

Energy & fatigue

High relevance

Reishi · 2025 · Journal Article · Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Pharmacokinetic and tissue distribution analysis of sporoderm-removed Ganoderma lucidum spore powder in rats.

Ganoderma lucidum (Lingzhi), a medicinal mushroom, is recognized for its broad pharmacological activities, including potential health and longevity benefits. Notably, several triterpenoids derived from its spores and fruiting body have demonstrated anti-inflammatory, anti-tumor, and immunomodulatory effects..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Cordyceps · 2025 · Research Article · Journal of cosmetic dermatology

Potential Cosmetic Applications of the Combined Extract of Panax ginseng, Ganoderma lucidum, Cordyceps militaris, and Several Asian Plants.

OBJECTIVE: Although bioactive compounds from single herbs are extensively explored in cosmetics, the synergistic potential of herbal combinations remains understudied..

OncologyImmune supportEnergy & fatigueSkin & hydration

High relevance

King Oyster · 2025 · Research Article · Foods (Basel, Switzerland)

Production and Optimization of Anti-Aging Peptides from Pleurotus eryngii Mushroom Feet: Mechanistic Insights via Integrated Transcriptomics and Metabolomics.

This study established an optimized process for obtaining anti-aging peptides from Pleurotus eryngii mushroom feet (PEMFPeps). Using response surface methodology, high yields of protein (51.31 ± 3.00%) and peptides (48.71 ± 0.17% hydrolysis degree) were achieved..

Cognition & nervesEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Cordyceps · 2025 · Research Article · Food science & nutrition

Selenium-Enriched Cordyceps militaris Polysaccharides Alleviate Insulin Resistance in HepG2 Cells by Regulating the PI3K/AKT/GLUT4 Signaling Pathway.

Metal ion-rich Cordyceps militaris polysaccharides (CMP) are obtained by biotransformation and chemical synthesis. The physicochemical properties and bioactivity of selenium-enriched CMP (Se-CMP) obtained using biotransformation remain unclear.

Immune supportEnergy & fatigueMetabolic health

High relevance

Oyster Mushroom · 2025 · Journal Article · Journal of food science

Simultaneous extraction and purification of polysaccharides and proteins from Pleurotus ostreatus using an aqueous two-phase system.

Pleurotus ostreatus is a nutrient-dense edible fungus renowned for its delicate texture, appealing flavor, and numerous potential health benefits. Simultaneous extraction within the framework of food resource processing facilitates the concurrent isolation and analysis of multiple target compounds..

Immune supportEnergy & fatigueMetabolic health

High relevance

Turkey Tail · 2025 · Research Article · Microbial cell factories

Studies on the treatment of anaerobically digested sludge by white-rot fungi: evaluation of the effect of Phanerochaete chrysosporium and Trametes versicolor.

BACKGROUND: The composition of anaerobically digested sludge is inherently complex, enriched with structurally complex organic compounds and nitrogenous constituents, which are refractory to biodegradation. These characteristics limit the subsequent rational utilization of resources from anaerobically digested sludge..

Energy & fatigueGut & microbiomeSkin & hydration