MycoData

Shiitake · 2012 · Journal Article · Journal of wood science

Effect of steam treatment for the enzymic saccharification of waste mushroom medium after cultivation of shiitake mushroom (Lentinula edodes) and enokitake mushroom (Flammulina velutipes)

Waste mushroom medium of shiitake and enokitake (WS and WE, respectively) was steamed (StmWS and StmWE, respectively) and saccharized with cellulase to obtain glucose which can be feedstock of bioethanol or other bioproducts..

King Oyster · 2012 · Journal Article · International journal of biological macromolecules

Optimization of extracellular glucan production from Pleurotus eryngii and its impact on angiogenesis.

Pleurotus eryngii, an edible mushroom with therapeutic potential was optimized using response surface methodology of four-factor Box-Behnken design for maximum mycelial biomass and extracellular glucan (EPS) production..

Maitake · 2012 · Journal Article · Journal of wood science

Storage of maitake mushroom (Grifola frondosa) culture medium after harvesting fruit bodies is an effective pretreatment for ethanol conversion

The storage of spent maitake culture medium (SMCM) under various conditions was investigated as a potential pretreatment of SMCM for increased ethanol conversion. When SMCM was stored at 25°C for 12 weeks, the glucose yield by enzymatic saccharification increased from 22 to 52%..

OncologyImmune supportMetabolic health

Yellow Morel · 2011 · Journal Article · Journal of food processing and preservation

Biomass and exopolysaccharide production by morchella esculenta in submerged culture using the extract from waste loquat (eriobotrya japonica l.) kernels

Detoxified loquat kernel extract (DLKE) and neutralized loquat kernel extract (LKE) prepared from waste loquat kernels were used as main carbon sources in the submerged and solid cultures of Morchella esculenta..

Metabolic healthLiver support

King Oyster · 2011 · Research Article · Saudi journal of biological sciences

Dietary effect of Pleurotus eryngii on biochemical function and histology in hypercholesterolemic rats.

This work was conducted to investigate diet supplement of king oyster mushroom fruiting bodies on biochemical and histological changes in hypercholesterolemic rats. Six-week old female Sprague-Dawley albino rats were divided into three groups of 10 rats each..

Shiitake · 2011 · Research Article · International journal of biochemistry and molecular biology

Physicochemical properties and acute toxicity studies of a lectin from the saline extract of the fruiting bodies of the shiitake mushroom, Lentinula edodes (Berk).

A lectin (LEL) was isolated from the fresh fruiting bodies of the shiitake mushroom Lentinula edodes by a combination of gel filtration chromatography on Sephadex G-150 and affinity chromatography on an N-acetyl-Dgalactosamine-Sepharose 4B column..

Immune supportMetabolic healthSkin & hydration

Almond Mushroom · 2010 · Journal Article · International journal of biological macromolecules

Chemical analysis of Agaricus blazei polysaccharides and effect of the polysaccharides on IL-1beta mRNA expression in skin of burn wound-treated rats.

Agaricus blazei polysaccharides were analyzed by GC-MS. Results indicated that the polysaccharides contained glucose (93.87%), mannose (3.54%), and arabinose (2.25%).

Immune supportMetabolic healthGut & microbiomeLiver support

Chaga · 2010 · Journal Article · Journal of food biochemistry

Glycosidase inhibitory activity and antioxidant properties of a polysaccharide from the mushroom inonotus obliquus

A water-soluble polysaccharide from Inonotus obliquus (IOPS) was isolated from the mushroom Inonotus obliquus (Fr.) Pilat. The chemical compositions, molecular weight and inhibitory activities on glycosidase and antioxidant properties of IOPS were investigated..

OncologyImmune supportEnergy & fatigueMetabolic health

Enoki · 2010 · Journal Article · The American journal of Chinese medicine

Purification, characterization and immuno-modulating properties of polysaccharides isolated from Flammulina velutipes mycelium.

To investigate the immuno-modulating activity of Flammulina velutipes mycelium, three different Flammulina velutipes polysaccharides (FVPs) were isolated by fractionation using gel filtration and were identified as the immunomodulators of murine peritoneal macrophages..

King Oyster · 2009 · Journal Article · Plant disease

Brown Blotch Caused by Pseudomonas tolaasii on Cultivated Pleurotus eryngii in Spain.

In 2006, symptoms of brown blotch were observed on cultivated Pleurotus eryngii (king oyster mushroom) in Castilla-La Mancha (Spain). Subsequently, between January and May of 2008, brown blotch affected 39.75% of the blocks of substrate cultivated, resulting in a considerable loss of production..

King Oyster · 2009 · Research Article · Mycobiology

Vegetative Growth and Phylogenetic Relationship of Commercially Cultivated Strains of Pleurotus eryngii based on ITS sequence and RAPD.

Pleurotus eryngii, known as king oyster mushroom has been widely used for nutritional and medicinal purposes. This study was initiated to screen the suitable conditions for mycelial growth and to determine the phylogenetic relationship of the selected strains..

Maitake · 2008 · Journal Article · Journal of nutritional science and vitaminology

A Water-Soluble Extract from Grifola frondosa, Maitake Mushroom, Decreases Lipid Droplets in Brown Adipocyte Tissue Cells

We investigated the effect of a water-soluble extract from Grifola frondosa, the maitake mushroom, on lipid droplets in brown adipocyte tissue (BAT) cells. This water-soluble extract inhibits the conversion of pre white adipocyte tissue (WAT) cells but does not inhibit that of pre BAT cells..

Enoki · 2008 · Journal Article · Bioscience, biotechnology, and biochemistry

Purification and Characterization of a Novel Exo-β-1,3-1,6-glucanase from the Fruiting Body of the Edible Mushroom Enoki (Flammulina velutipes)

To elucidate the role of beta-glucanases in the cell-wall degradation involved in morphogenesis, an exo-beta-1,3-1,6-glucanase (FvBGL1) was purified from fruiting bodies of the edible mushroom Enoki (Flammulina velutipes), and its enzymatic properties were studied..

Metabolic healthLiver support

Maitake · 2007 · Journal Article · The Journal of pharmacy and pharmacology

Anti-diabetic effect of an alpha-glucan from fruit body of maitake (Grifola frondosa) on KK-Ay mice.

We have evaluated the anti-diabetic effect of a alpha-glucan (MT-alpha-glucan) from the fruit body of maitake mushrooms (Grifola frondosa) on KK-Ay mice (a kind of genetical type 2 diabetes animal model)..

Metabolic healthGut & microbiome

King Oyster · 2007 · Journal Article · Plant disease

First Report of Pantoea sp. Induced Soft Rot Disease of Pleurotus eryngii in Korea.

The king oyster mushroom, Pleurotus eryngii, has become a popular crop because of its unique flavor and texture and is cultivated in many areas in Korea. In 2003, symptoms of water-soaked lesions and soft rot in the stipes and pileus of cultivated P.

Immune supportMetabolic healthLiver supportSkin & hydration

Reishi · 2023 · Research Support, Non U.S. Gov'T · Scientific reports

Amelioration of CCl4-induced oxidative stress and hepatotoxicity by Ganoderma lucidum in long evans rats.

Liver disease is a serious health problem affecting people worldwide at an alarming rate. The present study aimed to investigate the protective effects of Ganoderma lucidum against CCl4-induced liver toxicity in rats..

OncologyImmune supportMetabolic healthGut & microbiome

Enoki · 2023 · Research Support, Non U.S. Gov'T · The Journal of nutritional biochemistry

Auricularia polytricha and Flammulina velutipes reduce liver injury in DSS-induced Inflammatory Bowel Disease by improving inflammation, oxidative stress, and apoptosis through the regulation of TLR4/NF-κB signaling pathways.

Auricularia polytricha and Flammulina velutipes are two dietary mushrooms mostly consumed in China and known for their traditional use on gastric ulceration and to boost bowel movement..

OncologyImmune supportMetabolic health

Reishi · 2023 · Research Support, Non U.S. Gov'T · Experimental gerontology

Ganoderma lucidum polysaccharides ameliorates D-galactose-induced aging salivary secretion disorders by upregulating the rhythm and aquaporins.

Longer-term deterioration in saliva secretion has been observed to occur in response to aging. The functional deterioration of the salivary gland damages swallowing and chewing abilities and consequently reduces life quality of the elderly..

Reishi · 2023 · Research Support, Non U.S. Gov'T · mBio

GlMPC activated by GCN4 regulates secondary metabolism under nitrogen limitation conditions in Ganoderma lucidum.

Mitochondrial pyruvate carrier (MPC) is a pyruvate transporter that plays a crucial role in regulating the carbon metabolic flow and is considered an essential mechanism for microorganisms to adapt to environmental changes. However, it remains unclear how MPC responds to environmental stress in organisms..

Cordyceps · 2023 · Research Support, Non U.S. Gov'T · Food research international (Ottawa, Ont.)

Integrated metabolomics and transcriptomics reveal metabolites difference between wild and cultivated Ophiocordyceps sinensis.

Ophiocordyceps sinensis is a traditional medicinal fungus endemic to the alpine and high-altitude areas of the Qinghai-Tibet plateau. The scarcity of the wild resource has led to increased attention to artificially cultivated O.

OncologyImmune supportCognition & nervesMetabolic health

Oyster Mushroom · 2023 · Research Support, Non U.S. Gov'T · Food research international (Ottawa, Ont.)

Preparation, structural characterization and neuroprotective effects to against H2O2-induced oxidative damage in PC12 cells of polysaccharides from Pleurotus ostreatus.

Pleurotus ostreatus is one of the most common edible and medicinal fungi in life, and its polysaccharide has been a hot research topic in recent years. In this paper, a new intracellular polysaccharide component named P.

Immune supportEnergy & fatigueMetabolic healthRespiratory

Cordyceps · 2023 · Research Support, Non U.S. Gov'T · PloS one

The mechanism of action of Ophiocordyceps sinensis mycelia for prevention of acute lung injury based on non-targeted serum metabolomics.

Ophiocordyceps sinensis is a fungus with medicinal value in treating lung diseases, but no study has reported how to prevent acute lung injury using this fungus. The mice were divided into normal, model, positive control, and O..

Snow Fungus · 2022 · Brief Report · Microbiology resource announcements

Draft Genome Sequences of Two Basidiomycetous Yeasts, Tremella yokohamensis and Tremella fuciformis.

In this study, the genome sequences of two Basidiomycetous yeasts, Tremella yokohamensis and Tremella fuciformis, which have very similar morphological characteristics, were determined. The genomic sequence data obtained will be useful for understanding the taxonomy and metabolic-related genes of basidiomycete yeasts..

Immune supportMetabolic healthLiver support

Maitake · 2022 · Research Support, Non U.S. Gov'T · Frontiers in immunology

The anti-obesity effects of a water-soluble glucan from Grifola frondosa via the modulation of chronic inflammation.

Polysaccharides from Grifola frondosa (G. frondosa) have anti-obesity and anti-inflammatory activities.

Shiitake · 2022 · Research Support, Non U.S. Gov'T · Food research international (Ottawa, Ont.)

Understanding the promotion of heat treatment on the flavor of Lentinula edodes using metabolomics integrated with transcriptomics.

The transcriptome and metabolome analyses revealed the differentially expressed metabolites (DEMs) and genes (DEGs) in the dried Lentinula edodes' response to heat treatment..

Immune supportEnergy & fatigueMetabolic health

Lion's Mane · 2021 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

A novel polysaccharide from Hericium erinaceus: Preparation, structural characteristics, thermal stabilities, and antioxidant activities in vitro.

A novel polysaccharide fraction (HEP) from Hericium erinaceus was successively isolated and purified in the present study. We researched its structure and thermal stabilities, and further studied its antioxidant activities in vitro..

Shiitake · 2021 · Research Support, Non U.S. Gov'T · Fungal genetics and biology: FG & B

Comparative transcriptome analysis of abnormal cap and healthy fruiting bodies of the edible mushroom Lentinula edodes.

Lentinula edodes, a commercially important mushroom, is cultivated worldwide. Artificially cultivated L.

Chaga · 2021 · Research Support, Non U.S. Gov'T · Analytical methods: advancing methods and applications

Isolation of potential α-glucosidase inhibitor from Inonotus obliquus by combining ultrafiltration-liquid chromatography and consecutive high-speed countercurrent chromatography.

Inonotus obliquus is a rare medicinal fungus that contains several potential therapeutic ingredients. In this study, the α-glucosidase inhibitory activity of I.

Snow Fungus · 2021 · Research Support, Non U.S. Gov'T · Food research international (Ottawa, Ont.)

Moisture and caking resistant Tremella fuciformis polysaccharides microcapsules with hypoglycemic activity.

Tremella fuciformis polysaccharides (TPs) have attracted extensive attention as functional food constituents due to their bioactivity. However, β-D-glucan obtained from TPs is readily degraded by oxidation and easy to absorb water and agglomerate..

Energy & fatigueMetabolic healthRespiratory

Cordyceps · 2021 · Research Support, Non U.S. Gov'T · Translational research: the journal of laboratory and clinical medicine

Substantial involvement of TRPM7 inhibition in the therapeutic effect of Ophiocordyceps sinensis on pulmonary hypertension.

Ophiocordyceps sinensis (OCS), an entomopathogenic fungus, is known to exert antiproliferative and antitissue remodeling effects. Vascular remodeling and vasoconstriction play critical roles in the development of pulmonary hypertension (PH)..

Immune supportCognition & nervesMetabolic healthGut & microbiome

Shiitake · 2021 · Research Support, Non U.S. Gov'T · Journal of translational medicine

β-Glucan from Lentinula edodes prevents cognitive impairments in high-fat diet-induced obese mice: involvement of colon-brain axis.

BACKGROUND: Long-term high fat (HF) diet intake can cause neuroinflammation and cognitive decline through the gut-brain axis. (1, 3)/(1, 6)-β-glucan, an edible polysaccharide isolated from medical mushroom, Lentinula edodes (L.

Immune supportEnergy & fatigueMetabolic health

Oyster Mushroom · 2026 · Preprint · journal metadata

Ultrasound-Assisted Extraction of Polysaccharides from Pleurotus ostreatus By-Products: Box–Behnken Optimization and Low-Fat Cookies Formulation

Spent mushroom substrate (SMS), the main by-product of mushroom production, is rich in valuable compounds that could be recovered by ultrasound-assisted extraction (UAE) and exploited as fat-mimetic functional ingredients in food formulations..

Metabolic healthGut & microbiomeLiver support

Reishi · 2025 · Preprint · journal metadata

Integrated analysis of NAFLD mitigation mechanism by Ganoderma lucidum insoluble dietary fiber based on transcriptomics, metabolomics and gut microbiota

Abstract The study established a mouse model of NAFLD induced by a 12-week high-fat diet (HFD). Utilizing hepatic transcriptomics, 16S rDNA sequencing, and metabolomics, the study examined the mechanisms by which GIDF exerts hepatic protection and modulates lipid metabolism in NAFLD through the gut-liver axis.The….

OncologyImmune supportMetabolic healthSkin & hydration

Chaga · 2022 · Case Reports · Medicine

Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report.

RATIONALE: The Chaga mushroom (Hymenochaetaceae, Inonotus obliquus) is a fungus belonging to the Hymenochaetaceae family. It is parasitic on birch and other tree species.

Cordyceps · 2022 · Research Support, Non U.S. Gov'T · Scientific reports

Cordyceps cicadae and Cordyceps gunnii have closer species correlation with Cordyceps sinensis: from the perspective of metabonomic and MaxEnt models.

Cordyceps sinensis is a second-class nationally-protected medicinal fungus and functional food. Cordyceps sinensis resources are endangered, and finding new medicinal materials is a fast and economical way to meet the current demonstrated demand, which can effectively solve the shortage of C.

Cordyceps · 2020 · Comparative Study · Genomics

Alternative metabolic routes in channeling xylose to cordycepin production of Cordyceps militaris identified by comparative transcriptome analysis.

The responsive mechanism of C. militaris TBRC7358 on xylose utilization was investigated by comparative analysis of transcriptomes, growth kinetics and cordycepin productions.

Lion's Mane · 2020 · Preprint · journal metadata

Key metabolism pathways and regulatory mechanisms of high polysaccharide yielding in Hericium erinaceus

Abstract Background Hericium erinaceus, a rare edible and medicine fungus, is widely used in the food and medical field. H.

Immune supportCognition & nervesMetabolic healthGut & microbiome

Shiitake · 2020 · Preprint · journal metadata

β-glucan from Lentinula Edodes Prevents Cognitive Impairments in High-Fat Diet-Induced Obese Mice: Involvement of Colon-Brain Xxis

Abstract Background: Long-term high fat (HF) diet intake can cause neuroinflammation and cognitive decline through the gut-brain axis. (1, 3)/(1, 6)-β-glucan, an edible polysaccharide isolated from medical mushroom, Lentinula edodes ( L.

Enoki · 2019 · Preprint · journal metadata

Combining transcriptomics and metabolomics to characterize ergosterol biosynthesis in Flammulina velutipes during the fruiting process

Abstract Background: Flammulina velutipes (F. velutipes) is one of the most important mushrooms in Japan and China because of its potential medicinal and nutritional value.

OncologyMetabolic health

Cordyceps · 2017 · Published Erratum · Journal of diabetes research

Corrigendum to "Hypoglycemic Activity through a Novel Combination of Fruiting Body and Mycelia of Cordyceps militaris in High-Fat Diet-Induced Type 2 Diabetes Mellitus Mice".

[This corrects the article DOI: 10.1155/2015/723190.]..

Enoki · 2016 · Preprint · journal metadata

Selenium uptake, toxicity and reduction in Flammulina velutipes supplied with selenite

Recently, selenium (Se) enriched mushrooms have been exploited as diary Se supplements, but our knowledge of the metabolism process during the Se enrichment process is far from complete..

Cordyceps · 2015 · Journal Article · The Journal of Poultry Science

Effect of Cordyceps Militaris Waster Medium on Production Performance, Egg Traits and Egg Yolk Cholesterol of Laying Hens

Metadata-grounded summary: This journal article indexes research on Cordyceps militaris in The Journal of Poultry Science in 2015. MycoData maps the paper to energy & fatigue, metabolic health based on its title, species context, article metadata, and study classification..

Metabolic healthSkin & hydration

Chaga · 2008 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

A comparative study of analytical methods for alkali-soluble β-glucan in medicinal mushroom, Chaga (Inonotus obliquus)

Metadata-grounded summary: This journal article indexes research on Inonotus obliquus in Lebensmittel-Wissenschaft + [i.e. und] Technologie.

Yellow Morel · 2026 · Journal Article · Fitoterapia

OHR-LCMS based chemical profiling and dietary effects of morel mushroom Morchella esculenta (L.) Pers. on diet-induced obese zebrafish: Insights from physiological, biochemical, histological and ATR-FTIR spectroscopy.

Obesity is a complex metabolic disease caused by an energy imbalance, characterized by excessive weight gain, adiposity and disturbed lipid metabolism. Though several pharmacological anti-obesity drugs are available, their side effects have promoted interests towards natural alternatives..

Snow Fungus · 2026 · Journal Article · World journal of microbiology & biotechnology

Tissue cultivation conditions and transcriptome analysis of Tremella fuciformis primordia for industrial production purposes.

Direct acquisition of primordia represents a feasible approach for the industrial production of Tremella fuciformis fruit bodies, with stable tissue culture and multiplication of primordia being crucial steps. In this study, T.

Immune supportMetabolic healthLiver support

Reishi · 2026 · Journal Article · Applied biochemistry and biotechnology

Transcriptomic and Metabolomic Profiling of Heat Stress Responses and Ganoderic Acid Biosynthesis in Ganoderma lucidum.

Ganoderma lucidum (G. lucidum) produces ganoderic acids (GAs), which are pharmacologically important triterpenoids with hepatoprotective, anti-inflammatory, and immunomodulatory properties..

Immune supportEnergy & fatigueMetabolic health

Oyster Mushroom · 2026 · Research Article · Foods (Basel, Switzerland)

Ultrasound-Assisted Extraction of Polysaccharides from Pleurotus ostreatus By-Products: Box-Behnken Optimization and Low-Fat Cookies Formulation.

OncologyImmune supportMetabolic healthLiver support

Reishi · 2025 · Journal Article · Mushroom Science and Biotechnology

Analysis of functional components in preserving Ganoderma lucidum fruiting bodies

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Mushroom Science and Biotechnology in 2025. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

Oyster Mushroom · 2025 · Journal Article · Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan

Effects of adding unused fisheries materials in the cultivation of Pleurotus ostreatus

Metadata-grounded summary: This journal article indexes research on Pleurotus ostreatus in Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan in 2025. MycoData maps the paper to metabolic health based on its title, species context, article metadata, and study classification..