MycoData
Medicinal fungi research database
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Cognition & nerves
Cognition, nerve growth factor, neuroprotection, memory, and brain-health papers.
Species records
Species record
Oyster Mushroom
Pleurotus ostreatus
- Studies
- 1,947
- Avg relevance
- 53
- Latest
- 2026
Species record
Reishi · Lingzhi
Ganoderma lucidum
- Studies
- 1,830
- Avg relevance
- 60
- Latest
- 2026
Species record
Turkey Tail · Yun Zhi
Trametes versicolor
- Studies
- 1,828
- Avg relevance
- 41
- Latest
- 2026
Species record
Shiitake · Hua Gu
Lentinula edodes
- Studies
- 1,766
- Avg relevance
- 60
- Latest
- 2026
Species record
Cordyceps · Scarlet Club
Cordyceps militaris
- Studies
- 1,635
- Avg relevance
- 67
- Latest
- 2026
Species record
Cordyceps · Caterpillar Fungus
Ophiocordyceps sinensis
- Studies
- 1,576
- Avg relevance
- 59
- Latest
- 2026
Species record
Almond Mushroom · ABM
Agaricus blazei
- Studies
- 1,441
- Avg relevance
- 54
- Latest
- 2026
Species record
Enoki · Winter Mushroom
Flammulina velutipes
- Studies
- 1,403
- Avg relevance
- 47
- Latest
- 2026
Species record
King Oyster · Eryngii
Pleurotus eryngii
- Studies
- 1,278
- Avg relevance
- 60
- Latest
- 2026
Species record
Maitake · Hen of the Woods
Grifola frondosa
- Studies
- 1,276
- Avg relevance
- 48
- Latest
- 2026
Species record
Snow Fungus · Silver Ear
Tremella fuciformis
- Studies
- 1,052
- Avg relevance
- 29
- Latest
- 2026
Species record
Lion's Mane · Yamabushitake
Hericium erinaceus
- Studies
- 862
- Avg relevance
- 67
- Latest
- 2026
Species record
Chaga
Inonotus obliquus
- Studies
- 738
- Avg relevance
- 65
- Latest
- 2026
Species record
Mesima · Sanghwang
Phellinus linteus
- Studies
- 722
- Avg relevance
- 58
- Latest
- 2026
Species record
Niu-Chang-Chih
Antrodia camphorata
- Studies
- 496
- Avg relevance
- 63
- Latest
- 2026
Species record
Nameko · Nametake
Pholiota microspora
- Studies
- 421
- Avg relevance
- 29
- Latest
- 2026
Species record
Yellow Morel
Morchella esculenta
- Studies
- 392
- Avg relevance
- 42
- Latest
- 2026
Species record
Zhu Ling · Umbrella Polypore
Polyporus umbellatus
- Studies
- 263
- Avg relevance
- 55
- Latest
- 2026
Species record
Wood Ear · Kikurage
Auricularia auricula-judae
- Studies
- 254
- Avg relevance
- 51
- Latest
- 2026
Species record
Agarikon · Quinine Conk
Fomitopsis officinalis
- Studies
- 47
- Avg relevance
- 55
- Latest
- 2026
Articles
1,418 results
Showing 1,151–1,200 of 1,418
Lion's Mane · 2017 · Research Article · Journal of cellular and molecular medicine
A proteomics approach to identifying novel protein targets involved in erinacine A-mediated inhibition of colorectal cancer cells' aggressiveness.
Erinacine A, a major active component of a diterpenoid derivative isolated from Hericium erinaceus mycelium, has been demonstrated to exert anticancer effects. Herein, we present an investigation of the molecular mechanism of erinacine A induction associated with cancer cells' aggressive status and death..
Mesima · 2017 · Journal Article · The American journal of Chinese medicine
Hispolon Suppresses LPS- or LTA-Induced iNOS/NO Production and Apoptosis in BV-2 Microglial Cells.
Hispolon (HIS) is an active polyphenol compound derived from Phellinus linteus (Berkeley & Curtis), and our previous study showed that HIS effectively inhibited inflammatory responses in macrophages [Yang, L.Y., S.C. Shen, K.T.
Enoki · 2017 · Journal Article · Carbohydrate research
Properties of two fungal endo-β-1,3-galactanases and their synergistic action with an exo-β-1,3-galactanase in degrading arabinogalactan-proteins.
Arabinogalactan-proteins (AGPs) are plant proteoglycans, which are widely encountered in the plant kingdom, usually localized on the cell surface. The carbohydrate moieties of AGPs consist of β-1,3-galactan main chains and β-1,6-galactan side chains, to which other auxiliary sugars are attached..
Mesima · 2017 · Research Article · Oxidative medicine and cellular longevity
Protective Effects and Possible Mechanisms of Ergothioneine and Hispidin against Methylglyoxal-Induced Injuries in Rat Pheochromocytoma Cells.
Diabetic encephalopathy (DE) is often a complication in patients with Alzheimer's disease due to high blood sugar induced by diabetic mellitus. Ergothioneine (EGT) and hispidin (HIP) are antioxidants present in Phellinus linteus..
Lion's Mane · 2015 · Review · Critical reviews in biotechnology
Therapeutic potential of culinary-medicinal mushrooms for the management of neurodegenerative diseases: diversity, metabolite, and mechanism.
Mushrooms have long been used not only as food but also for the treatment of various ailments. Although at its infancy, accumulated evidence suggested that culinary-medicinal mushrooms may play an important role in the prevention of many age-associated neurological dysfunctions, including Alzheimer's and Parkinson's….
Lion's Mane · 2013 · Review · Journal of traditional and complementary medicine
Neuronal health - can culinary and medicinal mushrooms help?
Hericium erinaceus a culinary and medicinal mushroom is a well established candidate for brain and nerve health. Ganoderma lucidum, Grifola frondosa and Sarcodon scabrosus have been reported to have neurite outgrowth and neuronal health benefits..
Lion's Mane · 2012 · Review · journal metadata
Lion’s Mane
Metadata-grounded summary: This review indexes research on Hericium erinaceus in 2012. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..
Almond Mushroom · 2020 · Research Support, Non U.S. Gov'T · Journal of behavior therapy and experimental psychiatry
Context matters: The role of subjective arousal during Attentional Bias Modification targeting socially anxious students.
BACKGROUND AND OBJECTIVES: Attentional Bias Modification (ABM) paradigms targeting anxiety aim to reduce attentional biases for threatening stimuli and thereby reduce anxiety..
Almond Mushroom · 2020 · Research Support, Non U.S. Gov'T · Pain
Evaluating the efficacy of an attention modification program for patients with fibromyalgia: a randomized controlled trial.
Persons with chronic musculoskeletal pain may be hypervigilant for pain-related cues which, paradoxically, may be maintaining their pain. Several randomized controlled trials have assessed whether a modified dot-probe protocol (ie, attention bias modification [ABM]) reduces chronic pain- and pain-related symptoms in….
Zhu Ling · 2005 · Patent · journal metadata
COMPOSITION FOR RELIEVING HANGOVER AND IMPROVING LIVER FUNCTION BY REDUCING ALCOHOL CONCENTRATION AND ACETALDEHYDE CONCENTRATION IN BLOOD AND PREPARATION METHOD THEREOF
PURPOSE: A composition for relieving hangover and improving liver function and a preparation method thereof are provided, which composition reduces alcohol concentration and acetaldehyde concentration in blood after 30 minutes have passed since men drank, and relieves hangover including headache, heart beating,….
Shiitake · 2023 · Research Support, Non U.S. Gov'T · Neuroscience letters
"Eritadenine as a regulator of anxiety Disorders: An experimental and docking Approach".
Uncertainty persists regarding the specific chemical causal factors and their corresponding behavioral effects in anxiety disorders. Commonly employed first-line treatments for anxiety target G protein-coupled receptors (GPCRs), including inhibitors of monoaminergic systems..
Cordyceps · 2023 · English Abstract · Zhonghua shao shang yu chuang mian xiu fu za zhi
[Clinical characteristics and analysis of risk factors for heart injuries in 55 patients with lightning injury on plateau in Tibet Autonomous Region].
Objective: To explore the clinical characteristics and treatment outcomes of patients with lightning injury on plateau in Tibet Autonomous Region, and to analyze the risk factors for heart injuries in these patients. Methods: A retrospective case series study was conducted..
Almond Mushroom · 2023 · Dataset · Scientific data
MUSE-RASA captures human dimension in climate-energy-economic models via global geoAI-ML agent datasets.
This article provides a combined geospatial artificial intelligence-machine learning, geoAI-ML, agent-based, data-driven, technology-rich, bottom-up approach and datasets for capturing the human dimension in climate-energy-economy models..
King Oyster · 2010 · Research Support, Non U.S. Gov'T · Biological & pharmaceutical bulletin
Invariant Vα14 Natural Killer T Cell Activation by Edible Mushroom Acidic Glycosphingolipids
Invariant natural killer T (iNKT) cells regulate multi-immune response through Th1/Th2 cytokine release triggered by the recognition of CD1d-restricted glycosphingolipid antigens..
King Oyster · 2009 · Research Support, Non U.S. Gov'T · Acta crystallographica. Section D, Biological crystallography
Novel structural features in the GMC family of oxidoreductases revealed by the crystal structure of fungal aryl-alcohol oxidase.
Lignin biodegradation, a key step in carbon recycling in land ecosystems, is carried out by white-rot fungi through an H(2)O(2)-dependent process defined as enzymatic combustion..
Lion's Mane · 2005 · Journal Article · Journal for the Integrated Study of Dietary Habits
Yamabushitake (Hericium erinaceum) cultivation in cacao husk and in constituents in fruit body
Metadata-grounded summary: This journal article indexes research on Hericium erinaceus in Journal for the Integrated Study of Dietary Habits in 2005. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..
Cordyceps · 2004 · Journal Article · Biological and Pharmaceutical Bulletin
Mycelial Extract of Cordyceps ophioglossoides Prevents Neuronal Cell Death and Ameliorates β-Amyloid Peptide-Induced Memory Deficits in Rats
Ameliorating effects of methanol extracts of Basidiomycetes against in vitro and in vivo model of Alzheimer's disease were investigated. The extracts of Cordyceps ophioglossoides and Hypocrea citrina var.
Lion's Mane · 2001 · Journal Article · Journal for the Integrated Study of Dietary Habits
Effect of different strains and supplements on constituents in fruit, Yamabushitake (Hericium erinaceum) cultivated on sawdust substrate beding body
Metadata-grounded summary: This journal article indexes research on Hericium erinaceus in Journal for the Integrated Study of Dietary Habits in 2001. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..
Lion's Mane · 1997 · Journal Article · Food reviews international
Cultivation of yamabushitake (Hericium erinaceum).
Metadata-grounded summary: This journal article indexes research on Hericium erinaceus in Food reviews international in 1997. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..
Lion's Mane · 1995 · Journal Article · Food reviews international
Yamabushitake, Hericium erinaceum: bioactive substances and medicinal utilization.
Metadata-grounded summary: This journal article indexes research on Hericium erinaceus in Food reviews international in 1995. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..
Lion's Mane · 2020 · Research Article · Oxidative medicine and cellular longevity
Antia, a Natural Antioxidant Product, Attenuates Cognitive Dysfunction in Streptozotocin-Induced Mouse Model of Sporadic Alzheimer's Disease by Targeting the Amyloidogenic, Inflammatory, Autophagy, and Oxidative Stress Pathways.
BACKGROUND: Many neurodegenerative diseases such as Alzheimer's disease are associated with oxidative stress. Therefore, antioxidant therapy has been suggested for the prevention and treatment of neurodegenerative diseases..
Almond Mushroom · 2020 · Journal Article · Biological psychology
Does attention bias modification induce structural brain changes? A commentary on Abend et al. (2019).
The strength of research conclusions must follow from the strength of evidence. In this commentary I raise several issues with a recent paper "Brain structure changes induced by attention bias modification training" (Abend et al., 2019)..
Almond Mushroom · 2020 · Journal Article · Frontiers in neurology
Functional Outcome Prediction in Ischemic Stroke: A Comparison of Machine Learning Algorithms and Regression Models.
Background and Purpose: Stroke-related functional risk scores are used to predict patients' functional outcomes following a stroke event. We evaluate the predictive accuracy of machine-learning algorithms for predicting functional outcomes in acute ischemic stroke patients after endovascular treatment..
Almond Mushroom · 2020 · Journal Article · OncoTargets and therapy
PD-1/PD-L1 Inhibitor Combined with Chemotherapy Can Improve the Survival of Non-Small Cell Lung Cancer Patients with Brain Metastases.
INTRODUCTION: Immune checkpoint inhibitor (ICI) monotherapy has limited efficacy in patients with non-small cell lung cancer (NSCLC) and brain metastases (BMs). With the wide use of ICI-based combinations, the efficacy of different ICI combination strategies in patients with NSCLC and BMs needs to be further….
Almond Mushroom · 2020 · Journal Article · International journal of environmental research and public health
Understanding the Sociocognitive Process of Construction Workers' Unsafe Behaviors: An Agent-Based Modeling Approach.
Previous literature has recognized that workers' unsafe behavior is the combined result of both isolated individual cognitive processes and their interaction with others..
Maitake · 2018 · Journal Article · Molecular biology reports
Investigation of the protective effects of horse mushroom (Agaricus arvensis Schaeff.) against carbon tetrachloride-induced oxidative stress in rats.
Wild and cultured mushrooms have been extensively used for food and medicinal purposes all around the world. However, there is limited information on chemical composition, health enhancing effects and contributions on diet of some mushrooms (e.g., Agaricus arvensis) widely distributed in many countries including….
Chaga · 2007 · Patent · journal metadata
Composition comprising chaga mushroom extract having neuronal cell-protecting activity for preventing and treating brain disease
Metadata-grounded summary: This patent indexes research on Inonotus obliquus in 2007. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..
Lion's Mane · 2007 · Editorial · Radiation protection dosimetry
The Lion's Mane and the Occam's Razor.
Metadata-grounded summary: This editorial indexes research on Hericium erinaceus in Radiation protection dosimetry in 2007. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..
Turkey Tail · 2018 · Research Support, Non U.S. Gov'T · Scientific reports
A structural-chemical explanation of fungal laccase activity.
Fungal laccases (EC 1.10.3.2) are multi-copper oxidases that oxidize a wide variety of substrates. Despite extensive studies, the molecular basis for their diverse activity is unclear.
Turkey Tail · 2018 · Research Support, Non U.S. Gov'T · PloS one
Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected Trametes species from Serbia.
In a last few decades mushrooms are increasingly attracting attention as functional food and sources of biologically active compounds. Several Trametes species have been used for centuries in traditional medicine of East Asia cultures, but only T..
Lion's Mane · 2018 · Retracted Publication · Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry, and pharmacology
Erinacine Facilitates the Opening of the Mitochondrial Permeability Transition Pore Through the Inhibition of the PI3K/ Akt/GSK-3β Signaling Pathway in Human Hepatocellular Carcinoma.
BACKGROUND/AIMS: Erinacine, which is extracted from the medicinal mushroom Hericium erinaceus, is known to play anticancer roles in human cancers. The following study aims to investigate the role of erinacine in the opening of the mitochondrial permeability transition pore (MPTP) in hepatocellular carcinoma (HCC)….
Lion's Mane · 2018 · Research Support, Non U.S. Gov'T · BMC microbiology
Screening for inhibitors of mutacin synthesis in Streptococcus mutans using fluorescent reporter strains.
BACKGROUND: Within the polymicrobial dental plaque biofilm, bacteria kill competitors by excreting mixtures of bacteriocins, resulting in improved fitness and survival. Inhibiting their bacteriocin synthesis might therefore be a useful strategy to eliminate specific pathogens..
Mesima · 2016 · Research Support, Non U.S. Gov'T · Scientific reports
A proteomic analysis of mushroom polysaccharide-treated HepG2 cells.
The anti-tumor properties of fungal polysaccharides have gained significant recognition in Asia and tropical America. In this study, the differential expression of proteins in normal HepG2 cells and those treated with polysaccharides that had been isolated from Phellinus linteus (PL), Ganoderma lucidum (GL) and….
Enoki · 2016 · Research Support, Non U.S. Gov'T · Plant biotechnology journal
Improving nutritional quality and fungal tolerance in soya bean and grass pea by expressing an oxalate decarboxylase.
Soya bean (Glycine max) and grass pea (Lathyrus sativus) seeds are important sources of dietary proteins; however, they also contain antinutritional metabolite oxalic acid (OA). Excess dietary intake of OA leads to nephrolithiasis due to the formation of calcium oxalate crystals in kidneys..
Turkey Tail · 2011 · Journal Article · Applied microbiology and biotechnology
How is the reactivity of laccase affected by single-point mutations? Engineering laccase for improved activity towards sterically demanding substrates.
In spite of its broad specificity among phenols, Trametes versicolor laccase hardly succeeds in oxidizing hindered substrates. To improve the oxidation ability of this laccase towards bulky phenolic substrates, we designed a series of single-point mutants on the basis of the amino-acid layout inside the reducing….
Mesima · 2010 · Journal Article · Molecular nutrition & food research
Effects of mushroom-derived beta-glucan-rich polysaccharide extracts on nitric oxide production by bone marrow-derived macrophages and nuclear factor-kappaB transactivation in Caco-2 reporter cells: can effects be explained by structure?
Mushrooms are known for their immune-modulating and anti-tumour properties. The polysaccharide fraction, mainly beta-glucans, is responsible for the immune-modulating effects.
Yellow Morel · 2009 · Journal Article · Journal of Ayub Medical College, Abbottabad: JAMC
Ethno-botanical studies from Northern Pakistan.
BACKGROUND: In this research paper efforts have been made to document the ethno-botanical knowledge of important plant species found in Northern Pakistan. It includes Thandiani, Galiat, Kaghan, Swat, Buner, Dir, Chitral and Northern Areas of Pakistan.
Yellow Morel · 2009 · Journal Article · Food chemistry
Isolation and quantitative determination of ergosterol peroxide in various edible mushroom species
Ergosterol peroxide, the steroidal derivative with cytotoxic activity, has been isolated for the first time from the mycelium of edible and medicinal mushroom Hericium erinaceum (lion's mane mushroom) together with erinacine A..
Agarikon · 2013 · Comparative Study · International journal of medicinal mushrooms
Cytotoxicity of blended versus single medicinal mushroom extracts on human cancer cell lines: contribution of polyphenol and polysaccharide content.
The use of mushrooms contributes to human nutrition by providing low lipid content of lipids and high dietary fiber content, as well as significant content of other biologically active compounds such as polysaccharides, minerals, vitamins, and polyphenolic antioxidants..
Lion's Mane · 1983 · Historical Article · The American Journal of dermatopathology
"The Lion's Mane". Concerning the diagnostic acumen of Sherlock Holmes.
Metadata-grounded summary: This historical article indexes research on Hericium erinaceus in The American Journal of dermatopathology in 1983. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..
Lion's Mane · 2003 · Research Article · Journal of Shanxi Medical University
Evaluation of genetic toxicity and antimutagenicity of HEPS
Metadata-grounded summary: This research article indexes research on Hericium erinaceus in Journal of Shanxi Medical University in 2003. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..
Lion's Mane · 2001 · Journal Article · Zhongguo sheng hua yao wu za zhi
Study on the sterols of hericium erincceus extracts
Metadata-grounded summary: This journal article indexes research on Hericium erinaceus in Zhongguo sheng hua yao wu za zhi in 2001. MycoData maps the paper to cognition & nerves based on its title, species context, article metadata, and study classification..
Maitake · 1995 · Journal Article · Biological & pharmaceutical bulletin
Structure-Activity Relationship of (1→3)-β-D-Glucans in the Induction of Cytokine Production from Macrophages, in Vitro
In a previous study, we reported that one of the gel-forming (1-->3)-beta-D-glucans, grifolan (from Grifola frondosa, GRN), stimulated cytokine production from macrophages in vitro..
Lion's Mane · 2016 · Case Reports · Journal of neurosurgery
Endoscope-assisted endonasal versus supraorbital keyhole resection of olfactory groove meningiomas: comparison and combination of 2 minimally invasive approaches.
OBJECTIVE: Although the endonasal endoscopic approach has been applied to remove olfactory groove meningiomas, controversy exists regarding the efficacy and safety of this approach compared with more traditional transcranial approaches..
Lion's Mane · 2015 · Journal Article · Pharmacology, biochemistry, and behavior
Effects of amycenone on serum levels of tumor necrosis factor-α, interleukin-10, and depression-like behavior in mice after lipopolysaccharide administration.
Accumulating evidence suggests that inflammation plays a role in the pathophysiology of depression and that anti-inflammatory substances have antidepressant effects. Amycenone is obtained from extracts of the Yamabushitake (Hericium erinaceum)..
Lion's Mane · 2010 · Research Article · Frontiers in behavioral neuroscience
Of Lion Manes and Human Beards: Some Unusual Effects of the Interaction between Aggression and Sociality.
The function of manes in lions has been a topic of scientific interest since Darwin (1871) suggested that it provides protection in intraspecific fights. Recent experimental studies on wild lions have emphasized the role of female selection, but analyses of specific attack behaviors and targets, and the social….
Niu-Chang-Chih · 2015 · Research Support, Non U.S. Gov'T · Scientific reports
Antroquinonol Lowers Brain Amyloid-β Levels and Improves Spatial Learning and Memory in a Transgenic Mouse Model of Alzheimer's Disease.
Alzheimer's disease (AD) is the most common form of dementia. The deposition of brain amyloid-β peptides (Aβ), which are cleaved from amyloid precursor protein (APP), is one of the pathological hallmarks of AD.
Maitake · 2015 · Research Support, Non U.S. Gov'T · Biochemical and biophysical research communications
Lysophosphatidylethanolamine increases intracellular Ca(2+) through LPA(1) in PC-12 neuronal cells.
G protein-coupled receptors (GPCRs) have been implicated in lysophosphatidylethanolamine (LPE)-induced increases in intracellular Ca(2+) ([Ca(2+)]i), but in different cell types, this response may be dependent or independent of lysophosphatidic acid (LPA) GPCR..
Mesima · 2014 · Research Support, Non U.S. Gov'T · Experimental cell research
The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway.
Hispidin, a phenolic compound from Phellinus linteus (a medicinal mushroom), has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties. However, the cardioprotective efficacy of hispidin has not yet been investigated..
Maitake · 2013 · Research Support, Non U.S. Gov'T · BMC complementary and alternative medicine
Neurite outgrowth stimulatory effects of culinary-medicinal mushrooms and their toxicity assessment using differentiating Neuro-2a and embryonic fibroblast BALB/3T3.
BACKGROUND: Mushrooms are not only regarded as gourmet cuisine but also as therapeutic agent to promote cognition health. However, little toxicological information is available regarding their safety..