MycoData

Metadata-grounded summary: This journal article indexes research on Pleurotus ostreatus in Bulletin of the Forestry and Forest Products Research Institute in 2025. MycoData maps the paper to metabolic health based on its title, species context, article metadata, and study classification..

Metabolic health

High relevance

Snow Fungus · 2025 · Journal Article · Food Chemistry: X

Possible role of Tremella fuciformis polysaccharide in modulating in vitro digestion of potato starch digesta

The effect of deproteinized Tremella olysaccharide (DTP) on the in vitro digestion of potato starch (PS) was investigated. DTP reduced the hydrolysis rate of PS in a concentration-dependent manner, with digestion rates of 76.99 %, 72.03 %, and 29.73 % after 180 min for 0.3, 0.6, and 1.2 mg/mL DTP, respectively..

Immune supportMetabolic healthGut & microbiome

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Snow Fungus · 2025 · Research Article · Food chemistry: X

Possible role of Tremella fuciformis polysaccharide in modulating in vitro digestion of potato starch digesta.

Immune supportMetabolic healthGut & microbiome

High relevance

Reishi · 2025 · Preprint · journal metadata

Potential Mechanism of Ganoderma lingzhi (lingzhi) in Treating Diabetes Mellitus via Bioinformatics and Network Pharmacology

This study used bioinformatics and network pharmacology to explore Ganoderma lingzhi’s ”multi-component-multi-target-multi-pathway” mechanism in treating diabetes by comparing active components of its fruiting bodies and spore powder.Active components/targets of lingzhi were from TCMSP/CNKI, diabetes-related targets….

Immune supportEnergy & fatigueMetabolic health

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Reishi · 2025 · Research Article · NPJ science of food

Revealing the mechanism of Ganoderma lucidum insoluble dietary fiber alleviating NAFLD through transcriptomics and metabolomics.

The study established a mouse model of NAFLD induced by a 12-week high-fat diet (HFD). Utilizing hepatic transcriptomics, 16S rDNA sequencing, and metabolomics, the study examined the mechanisms by which GIDF exerts hepatic protection and modulates lipid metabolism in NAFLD through the gut-liver axis.The results….

Immune supportMetabolic healthGut & microbiomeLiver support

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Reishi · 2025 · Journal Article · International journal of biological macromolecules

Structure-activity relationship of synthesized glucans from Ganoderma lucidum with in vitro hypoglycemic activity.

The synthetic polysaccharides, which have precise structure, can be used to design new drugs by comparing structure-activity relationships (SAR). Improved protein stability may be due to the interaction between the polysaccharides and protein, which includes covalent and noncovalent interactions..

Immune supportMetabolic health

High relevance

Reishi · 2025 · Research Article · Foods (Basel, Switzerland)

Widely Targeted Metabolomics Decodes Metabolic Remodeling and Functional Shifts in Ganoderma lucidum-Fermented Green Tea Infusion.

This study used a targeted metabolomics approach to examine changes in metabolites within green tea infusions fermented by G. lucidum (TFG) and evaluate the in vitro antioxidant and lipid-lowering properties of TFG..

Metabolic health

High relevance

Maitake · 2024 · Research Article · Applied microbiology and biotechnology

A newly discovered glycosyltransferase gene UGT88A1 affects growth and polysaccharide synthesis of Grifola frondosa.

Grifola frodosa polysaccharides, especially β-D-glucans, possess significant anti-tumor, antioxidant and immunostimulatory activities. However, the synthesis mechanism remains to be elucidated.

OncologyImmune supportMetabolic health

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Cordyceps · 2024 · Research Article · Metabolites

Accumulation Characteristics of Natural Ophiocordyceps sinensis Metabolites Driven by Environmental Factors.

The environment is an important factor affecting the composition and abundance of metabolites in O. sinensis, which indirectly determines its edible function and medicinal potential..

Metabolic health

High relevance

Niu-Chang-Chih · 2024 · Research Article · Nutrients

Antrodia camphorata Supplementation during Early Life Alters Gut Microbiota and Inhibits Young-Onset Intestinal Tumorigenesis in APC1638N Mice Later in Life.

Young-onset colorectal cancer is an increasing concern worldwide due to the growing prevalence of Westernized lifestyles in childhood and adolescence. Environmental factors during early life, particularly early-life nutrition, significantly contribute to the increasing incidence..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Reishi · 2024 · Journal Article · Journal of biotechnology

Development of a 2A peptide-based multigene expression system and its application for enhanced production of ganoderic acids in Ganoderma lucidum.

Ganoderma has received much attention for its medicinal value, but the manipulation of multiple genes remains a challenge, hindering the genetic engineering of this species for the development of cell factories..

Metabolic health

High relevance

Reishi · 2024 · Research Article · Veterinary sciences

Effects of Ganoderma lucidum Powder on the Growth Performance, Immune Organ Weights, Cecal Microbiology, Serum Immunoglobulins, and Tibia Minerals of Broiler Chickens.

A total of 640 one-day-old Cobb 500 MV × Cobb 500 FF mixed broilers were randomly assigned to one of four experimental treatments with four replicates per treatment and 40 birds per replicate for 32 days..

Immune supportEnergy & fatigueMetabolic health

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Oyster Mushroom · 2024 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Enhancing protein extraction from Pleurotus ostreatus using synergistic pH-shifting and ultrasonic technology: Optimization via RSM and 1H NMR-based metabolomic profiling

This study explores the impact of ultrasound and pH-shifting on protein extraction from P. ostreatus, employing ¹H NMR techniques to monitor metabolites and elucidate the extraction mechanism.

Metabolic health

High relevance

Oyster Mushroom · 2024 · Journal Article · Chemosphere

Expression of Concern: Efficient decolorization and detoxification of triarylmethane and azo dyes by porous-cross-linked enzyme aggregates of Pleurotus ostreatus laccase.

Metadata-grounded summary: This journal article indexes research on Pleurotus ostreatus in Chemosphere in 2024. MycoData maps the paper to metabolic health based on its title, species context, article metadata, and study classification..

Metabolic health

High relevance

Cordyceps · 2024 · Preprint · journal metadata

Improvement of nucleotide content of Cordyceps tenuipes by Schisandra chinensis: fermentation process optimization and application prospects

Abstract Nucleotides are important components and the main indicators for judging Cordyceps quality. To increase the nucleoside content of Cordyceps tenuipes for enhancing the efficacy activity.

Metabolic health

High relevance

Niu-Chang-Chih · 2021 · Review · Natural product reports

Terpenoids from the medicinal mushroom Antrodia camphorata: chemistry and medicinal potential.

Covering: up to February 2020Antrodia camphorata is a medicinal mushroom endemic to Taiwan for the treatment of intoxication, liver injury, cancer, and inflammation..

OncologyImmune supportCognition & nervesMetabolic health

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Almond Mushroom · 2020 · Journal Article · Zhongguo shi yan xue ye xue za zhi

[Inhibitory Effects of Agaricus Blazei Murrill (FA-2-b-β) on Proliferation of Chronic Myeloid Leukemia Cells in vivo and Its Mechanism].

OBJECTIVE: To investigated the anti-tumor in vivo effect and mechanism of the acid RNA protein complex (FA-2-b-β) of Agaricus blazei Murrill extract. METHODS: CCK-8 method was used to detected the inhibitory effect of FA-2-b-β on proliferation of primary CML cells from newly diagnosed CML patients, the CML mouse model….

OncologyImmune supportMetabolic health

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Lion's Mane · 2020 · Journal Article · Journal of food biochemistry

A novel oligosaccharide isolated from Hericium erinaceus and its protection against LPS‐induced Caco‐2 cells via the TLR4/NF‐κB pathway

A novel oligosaccharide showed that protection against LPS‐induced Caco‐2 cells was purified from the mycelium of Hericium erinaceus (HE). WEP‐1 is mainly composed of neutral monosaccharides with molecular weight of 4,010 Da and of mannose, glucose, and galactose in a molar ratio of 1.2:16.9:1..

Metabolic healthGut & microbiome

High relevance

Enoki · 2020 · Journal Article · Journal of animal physiology and animal nutrition

A novel polysaccharide isolated from Flammulina velutipes, characterization, macrophage immunomodulatory activities and its impact on gut microbiota in rats.

The structural characteristics of a novel Flammulina velutipes polysaccharide (FVP2) were explored in this study. Besides, immunomodulatory activities of FVP2 on RAW 264.7 cell and its impact on gut microbiota in rats were investigated..

Immune supportMetabolic healthGut & microbiome

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Maitake · 2020 · Journal Article · Journal of ethnopharmacology

Anti-diabetic effects of Grifola frondosa bioactive compound and its related molecular signaling pathways in palmitate-induced C2C12 cells.

ETHNOPHARMACOLOGICAL RELEVANCE: Grifola frondosa (GF), a high value medicinal mushroom, is popularly consumed as traditional medicines and health foods in China and Japan. It is a herbal medicine traditionally used for treating inflammation, cancer and diabetes..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms

Bioactive Fractions from the Chinese Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycetes), Elucidate Adaptogenic Role against Hypoxia Stress.

Ophiocordyceps sinensis, a high-altitude medicinal mushroom, is widely revered in traditional medicine for its antiproliferative, antihypercholesterolemic, energy enhancement, etc. properties.

Energy & fatigueMetabolic health

High relevance

Chaga · 2020 · Research Article · ACS omega

Cecal Butyrate (Not Propionate) Was Connected with Metabolism-Related Chemicals of Mice, Based on the Different Effects of the Two Inonotus obliquus Extracts on Obesity and Their Mechanisms.

Obesity is a metabolic disease and causes significant changes in host and gut microbial metabolite levels. However, little research has been done on the relationship between host and gut microbial metabolites..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Lion's Mane · 2020 · Journal Article · International journal of biological macromolecules

Characterization of polysaccharides isolated from Hericium erinaceus and their protective effects on the DON-induced oxidative stress.

In this study, the structure characteristic of the Hericium erinaceus polysaccharide (HEP) was investigated using Fourier transformed infrared spectrometry (FT-IR), gas chromatography-mass spectrometry (GC-MS), gel permeation chromatography (GPC), methylation and nuclear magnetic resonance (NMR)..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Cordyceps · 2020 · Journal Article · Food research international (Ottawa, Ont.)

Comparative metabolic profiling of Ophiocordyceps sinensis and its cultured mycelia using GC–MS

Ophiocordyceps sinensis, one of the well-known traditional Chinese medicine, has multiple health-promoting effects. It is used as herbal remedy and health food in Asian countries, together with its cultured mycelia used as a substitute of natural O.

Metabolic health

High relevance

Enoki · 2020 · Research Article · Journal of animal science and biotechnology

Determination of the available energy values and amino acid digestibility of Flammulina velutipes stem waste and its effects on carcass trait and meat quality fed to growing-finishing pigs.

BACKGROUND: Flammulina velutipes stem waste (FVS) is the by-product of mushroom industry. The objectives of this study were to determine the available energy and amino acid digestibility of FVS fed to pigs, and to evaluate the effects of dietary FVS inclusion on growth performance, biochemical profile of serum, fecal….

Cognition & nervesEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Enoki · 2020 · Journal Article · Food & function

Effects of a β-type glycosidic polysaccharide from Flammulina velutipes on anti-inflammation and gut microbiota modulation in colitis mice.

Using the Flammulina velutipes polysaccharide (FVP) extracted from our previous study, herein, we investigated the improvement of this starch-free β-type glycosidic polysaccharide in alleviating dextran sodium sulfate-induced ulcerative colitis (UC) in mice..

Immune supportMetabolic healthGut & microbiome

High relevance

Shiitake · 2020 · Journal Article · International journal of biological macromolecules

Effects of freeze drying and hot-air drying on the physicochemical properties and bioactivities of polysaccharides from Lentinula edodes.

Fresh Lentinula edodes were dried using two process technologies-freeze drying (FD) and hot-air drying (HD). The physicochemical, antioxidant and immunomodulatory properties of purified polysaccharides from dried L.

Immune supportMetabolic health

High relevance

Almond Mushroom · 2020 · Clinical Trial Protocol · Trials

Effects of Transcranial Direct Current Stimulation (tDCS) and Approach Bias Modification (ABM) training on food cravings in people taking antipsychotic medication.

BACKGROUND: Antipsychotic drug-induced weight gain puts individuals with schizophrenia at increased cardiometabolic risk. As a potential intervention for this problem, we describe the theoretical background and a protocol for a feasibility randomised controlled trial (RCT) of approach bias modification (ABM) training….

Cognition & nervesMetabolic health

High relevance

Turkey Tail · 2020 · Journal Article · Current microbiology

Extracellular and Intracellular Polysaccharide Extracts of Trametes versicolor Improve Lipid Profiles Via Serum Regulation of Lipid-Regulating Enzymes in Hyperlipidemic Mice.

Trametes versicolor extracts have been shown to have health-promoting benefits in hypercholesterolemia, obesity, hepatic steatosis, and cardiovascular disease. However, hypolipidemic or the anti-hyperlipidemic effects of polysaccharide extracts of T.

Immune supportMetabolic healthLiver support

High relevance

Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms

Fruiting Bodies of Chinese Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycetes) Alleviate Diabetes-Associated Oxidative Stress.

Hyperglycemia-induced complications, the major causes of death in diabetes, are closely related to the elevated oxidative stress. Our previous study indicated that fruiting bodies of Ophiocordyceps sinensis attenuated polydipsia and hyperglycemia in diabetic rats..

Metabolic healthLiver support

High relevance

Maitake · 2020 · Journal Article · International journal of biological macromolecules

Hypoglycemic and hypolipidemic activities of Grifola frondosa polysaccharides and their relationships with the modulation of intestinal microflora in diabetic mice induced by high-fat diet and streptozotocin.

This study aimed to investigate the hypoglycemic and hypolipidemic activities of polysaccharides from Grifola frondosa (GFP) in diabetic mice induced by high-fat diet (HFD) and streptozotocin (STZ)..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Maitake · 2020 · Journal Article · International journal of biological macromolecules

Hypoglycemic and hypolipidemic mechanism of organic chromium derived from chelation of Grifola frondosa polysaccharide-chromium (III) and its modulation of intestinal microflora in high fat-diet and STZ-induced diabetic mice.

Polysaccharide from Grifola frondosa is an excellent metal-ion chelating agent owing to its distinctive structure and outstanding functional activities. Our previous research has successfully synthesized novel organic chromium derived from the chelation ofG.

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Lion's Mane · 2020 · Journal Article · International journal of biological macromolecules

Isolation and structural characterization of a novel polysaccharide from Hericium erinaceus fruiting bodies and its arrest of cell cycle at S-phage in colon cancer cells.

The fruiting body of Hericium erinaceus has been used to treat digestive system disorder-related diseases for over 2000 years in China. A novel polysaccharide, HEFP-2b, was obtained from H.

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Oyster Mushroom · 2020 · Journal Article · Bioresource technology

Metagenomic analysis revealed the succession of microbiota and metabolic function in corncob composting for preparation of cultivation medium for Pleurotus ostreatus.

Metagenomic sequencing was used to reveal the dynamic changes in microbiota and the metabolic functions in corncob composting for preparing cultivation medium of Pleurotus ostreatus. Results showed that the changes of physicochemical properties lead to different dominant phylum at different stages of composting..

Metabolic healthGut & microbiome

High relevance

Shiitake · 2020 · Journal Article · Food and Bioproducts Processing

Parametric characterization of the initial pH effect on the polysaccharides production by Lentinula edodes in submerged culture

Edible fungus Lentinula edodes (L. edodes) produces exo-polysaccharides (EPS), which have been obtained from submerged mycelia cultures.

Immune supportMetabolic health

High relevance

Oyster Mushroom · 2020 · Journal Article · International journal of biological macromolecules

Physicochemical characterization and antitumor activity in vitro of a selenium polysaccharide from Pleurotus ostreatus.

Selenium-enriched polysaccharides have been gaining great attention for their antitumor activity in recent years. In this study, a novel selenium polysaccharide fraction (Se-POP-3) produced by Pleurotus ostreatus was characterized and its antitumor activity explored at cellular level..

OncologyImmune supportMetabolic health

High relevance

Cordyceps · 2020 · Journal Article · International journal of medicinal mushrooms

Protection against X-Ray Irradiation Injury by Chinese Caterpillar Medicinal Mushroom Ophiocordyceps sinensis (Ascomycetes) Polysaccharides in Mice.

Polysaccharides are one of the main active ingredients of Ophiocordyceps sinensis, a traditional Chinese medicinal mushroom. In this study, we investigated the protective effect of O.

Immune supportMetabolic health

High relevance

Mesima · 2020 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Protective Effects of Phellinus linteus Mycelium on the Development of Osteoarthritis after Monosodium Iodoacetate Injection.

OBJECTIVE: The aim of this study was to identify the protective effects of Phellinus linteus mycelium (PLM) and its possible mechanisms in a model of monosodium iodoacetate- (MIA-) induced osteoarthritis (OA)..

Immune supportMetabolic health

High relevance

Maitake · 2020 · Journal Article · International journal of biological macromolecules

Regulatory effect of Grifola frondosa extract rich in polysaccharides and organic acids on glycolipid metabolism and gut microbiota in rats.

The present study investigated the composition of water extract of Grifola frondosa (GFWE) and its regulatory effects on glycolipid metabolism and gut microbiota in rats..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Snow Fungus · 2020 · Journal Article · International journal of medicinal mushrooms

Structural Analysis and Antioxidant Activity of Extracellular Polysaccharides Extracted from Culinary-Medicinal White Jelly Mushroom Tremella fuciformis (Tremellomycetes) Conidium Cells.

Using Tremella fuciformis conidium cells for submerged fermentation is a cost-effective way to harvest bioactive compounds. In this study, we emphasized the structural and functional analysis of extracellular polysaccharides (EPS) extracted from T.

Immune supportMetabolic health

High relevance

Maitake · 2020 · Journal Article · Journal of food biochemistry

The hypoglycemic and renal protective effects of Grifola frondosa polysaccharides in early diabetic nephropathy

Grifola frondosa is a basidiomycete polypore fungus. Polysaccharides from G.

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Lion's Mane · 2020 · Research Article · Frontiers in nutrition

The Inhibitory Effects of Hericium erinaceus β-glucan on in vitro Starch Digestion.

β-glucan has attracted extensive attention due to its health promoting effects, such as lowering the blood sugar and lipids levels, and enhancing immunity. In this study, three different β-glucans (HEBG-1, HEBG-2, HEBG-3) were obtained from Hericium erinaceus by sodium hydroxide, β-1,3-glucanase and β-1,6-glucanase,….

Immune supportMetabolic healthGut & microbiome

High relevance

Maitake · 2020 · Journal Article · Glycoconjugate journal

The preparation of a cold-water soluble polysaccharide from Grifola frondosa and its inhibitory effects on MKN-45 cells.

In this study, a novel water soluble polysaccharide (named GFP-4) was extracted from Grifola frondosa at 4 oC, and its preliminary structure and inhibitory effects on human gastric carcinoma MKN-45 cells through the Fas/FasL death receptor apoptosis pathway were investigated..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Maitake · 2020 · Journal Article · International journal of biological macromolecules

The role of Rho1 gene in the cell wall integrity and polysaccharides biosynthesis of the edible mushroom Grifola frondosa.

Grifola frondosa polysaccharides, especially β-glucans, showed the significant antitumor, hypoglycemic, and immune-stimulating activities. In the present study, a predominant regulatory subunit gfRho1p of β-1,3-glucan synthase in G..

OncologyImmune supportMetabolic health

High relevance

Maitake · 2020 · Journal Article · International journal of biological macromolecules

UDP-glucose pyrophosphorylase gene affects mycelia growth and polysaccharide synthesis of Grifola frondosa.

To elucidate potential roles of UDP-glucose pyrophosphorylase (UGP) in mycelial growth and polysaccharide synthesis of Grifola frondosa, a putative 2036-bp UDP-glucose pyrophosphorylase gene gfugp encoding a 53.17-kDa protein was cloned and re-annotated..

Immune supportMetabolic health

High relevance

Enoki · 2020 · Journal Article · International journal of biological macromolecules

Using Flammulina velutipes derived chitin-glucan nanofibrils to stabilize palm oil emulsion:A novel food grade Pickering emulsifier.

We herein report chitin-glucan nanofibrils from edible mushroom Flammulina velutipes (CGNFs) as a novel stabilizer for palm oil Pickering emulsion (o/w, 30:70, v:v). Generally, these CGNFs being composed of glucose and glucosamine, are threadlike with 4.9 ± 1.2 nm wide and 222.6 ± 91.9 nm long..

Metabolic health

High relevance

Zhu Ling · 2019 · Journal Article · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[A landscape of transcriptome analysis of three sclerotia growth stages in Polyporus umbellatus].

Polyporus umbellatus,a traditional Chinese precious medicine as long been used for eliminating dampness,diuresis and have effect on cancer,getting more and more popularly in China recently. And the developmental metabolic process of the medicinal fungus,P.

OncologyMetabolic health

High relevance

Zhu Ling · 2019 · Journal Article · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Study on polysaccharide content and monosaccharide composition of Polyporus umbellatus from different production areas].

In order to provide scientific basics for exploitation and sufficient application of Polyporus umbellatus resources and study the monosaccharide composition of P. umbellatus polysaccharides,the anthrone-sulfuric acid method was applied to compare polysaccharide content of P.

Immune supportMetabolic health

High relevance

Lion's Mane · 2019 · Research Article · Molecules (Basel, Switzerland)

Absolute Bioavailability, Tissue Distribution, and Excretion of Erinacine S in Hericium erinaceus Mycelia.

Erinacine S, so far known to have been produced only in Hericium erinaceus mycelia, has just recently been discovered and is able to reduce amyloid plaque growth and improve neurogenesis in aged brain of rats..

Cognition & nervesMetabolic healthGut & microbiomeLiver support

High relevance

Maitake · 2019 · Journal Article · Applied biochemistry and biotechnology

Anti-Diabetic and Anti-Nephritic Activities of Grifola frondosa Mycelium Polysaccharides in Diet-Streptozotocin-Induced Diabetic Rats Via Modulation on Oxidative Stress.

Grifola frondosa is an edible fungus with a variety of potential pharmacological activities. This study investigates the hypoglycemic, anti-diabetic nephritic, and antioxidant properties of G.

Immune supportEnergy & fatigueMetabolic health