MycoData

Oxidation of low-density lipoprotein (LDL) has been strongly suggested as the key factor in the pathogenesis of atherosclerosis. Mushrooms have been implicated in having preventive effects against chronic diseases due especially to their antioxidant properties..

Metabolic health

High relevance

King Oyster · 2014 · Research Support, Non U.S. Gov'T · Fungal biology

Potential of a white-rot fungus Pleurotus eryngii F032 for degradation and transformation of fluorene.

The white-rot fungus Pleurotus eryngii F032 showed the capability to degrade a three fused-ring aromatic hydrocarbons fluorene. The elimination of fluorene through sorption was also investigated.

Metabolic health

High relevance

King Oyster · 2014 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Purification, characterization and antitumor activity of polysaccharides from Pleurotus eryngii residue.

A novel water-soluble polysaccharide from Pleurotus eryngii residue was isolated and further purified by DEAE cellulose-52 chromatography and Sephadex G-100 size-exclusion chromatography to yield PEPE-1, PEPE-2 and PEPE-3. Molecular weights were determined by high-performance size-exclusion chromatography (HPSEC)..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Cordyceps · 2014 · Research Support, Non U.S. Gov'T · BioMed research international

Studies on the antidiabetic activities of Cordyceps militaris extract in diet-streptozotocin-induced diabetic Sprague-Dawley rats.

Due to substantial morbidity and high complications, diabetes mellitus is considered as the third "killer" in the world. A search for alternative antidiabetic drugs from herbs or fungi is highly demanded..

Metabolic healthLiver support

High relevance

Chaga · 2014 · Research Support, Non U.S. Gov'T · Phytochemistry

Terpenoids with alpha-glucosidase inhibitory activity from the submerged culture of Inonotus obliquus.

Lanostane-type triterpenoids, inotolactones A and B, a drimane-type sesquiterpenoid, inotolactone C, and five known terpenoids 6β-hydroxy-trans-dihydroconfertifolin, inotodiol, 3β,22-dihydroxyanosta-7,9(11),24-triene, 3β-hydroxycinnamolide, and 17-hydroxy-ent-atisan-19-oic acid, were isolated from the submerged….

Metabolic health

High relevance

King Oyster · 2014 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

The excreted polysaccharide of Pleurotus eryngii inhibits the foam-cell formation via down-regulation of CD36.

Previous study has verified the polysaccharide from the fruiting body of Pleurotus eryngii (PEPE) is capable of decreasing the lipid content in both of cell-line and mouse model. However, little is known about underlying mechanisms and whether this bioactive polysaccharide exists in submerged culture..

Immune supportMetabolic healthGut & microbiome

High relevance

Almond Mushroom · 2014 · Research Support, Non U.S. Gov'T · BioMed research international

The protective effect of Agaricus blazei Murrill, submerged culture using the optimized medium composition, on alcohol-induced liver injury.

Agaricus blazei Murrill (ABM), an edible mushroom native to Brazil, is widely used for nonprescript and medicinal purposes. Alcohol liver disease (ALD) is considered as a leading cause for a liver injury in modern dietary life, which can be developed by a prolonged or large intake of alcohol..

Immune supportMetabolic healthLiver support

High relevance

Lion's Mane · 2013 · Research Support, Non U.S. Gov'T · BMC complementary and alternative medicine

Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats.

BACKGROUND: Hericium erinaceus, as a commonly used medicine or food, has attracted much attention due to its health effects when used as a home remedy for some diseases..

Metabolic healthLiver support

High relevance

King Oyster · 2013 · Research Support, Non U.S. Gov'T · Journal of lipid research

Binding of a pleurotolysin ortholog from Pleurotus eryngii to sphingomyelin and cholesterol-rich membrane domains.

A mixture of sphingomyelin (SM) and cholesterol (Chol) exhibits a characteristic lipid raft domain of the cell membranes that provides a platform to which various signal molecules as well as virus and bacterial proteins are recruited..

Cognition & nervesMetabolic healthRespiratory

High relevance

King Oyster · 2013 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Characterization of polysaccharides with marked inhibitory effect on lipid accumulation in Pleurotus eryngii.

Mushrooms have a great potential for the production of useful bioactive metabolites. To explore the bioactive compounds from edible mushrooms for interfering with the development of macrophage-derived foam cells, which is recognized as the hallmark of early atherosclerosis, eight types of mushrooms polysaccharides had….

Immune supportMetabolic health

High relevance

King Oyster · 2013 · Research Support, Non U.S. Gov'T · Bioprocess and biosystems engineering

Identification of naphthalene metabolism by white rot fungus Pleurotus eryngii.

The use of biomaterials or microorganisms in PAHs degradation had presented an eye-catching performance. Pleurotus eryngii is a white rot fungus, which is easily isolated from the decayed woods in the tropical rain forest, used to determine the capability to utilize naphthalene, a two-ring polycyclic aromatic….

Energy & fatigueMetabolic health

High relevance

King Oyster · 2013 · Research Support, Non U.S. Gov'T · Biological & pharmaceutical bulletin

Improvement of Depression-Like Behavior and Memory Impairment with the Ethanol Extract of Pleurotus eryngii in Ovariectomized Rats

Ethanol extract of Pleurotus eryngii (DC.) QUÉL has estrogen-like activities that protect against bone loss caused by estrogen deficiency. In the present study, we investigated the effect of P.

Cognition & nervesEnergy & fatigueMetabolic health

High relevance

Maitake · 2013 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

MT-α-glucan from the fruit body of the maitake medicinal mushroom Grifola frondosa (higher Basidiomyetes) shows protective effects for hypoglycemic pancreatic β-cells.

The hypoglycemic effect of an α-glucan (designated here as MT-α-glucan) from the fruit body of the Maitake medicinal mushroom, Grifola frondosa, on a murine type 2 diabetes mellitus (T2DM) model was evaluated..

Metabolic healthLiver support

High relevance

Mesima · 2013 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Polysaccharide from Phellinus linteus induces S-phase arrest in HepG2 cells by decreasing calreticulin expression and activating the P27kip1-cyclin A/D1/E-CDK2 pathway.

ETHNOPHARMACOLOGY RELEVANCE: Our previous study showed that the proteoglycan P1 from Phellinus linteus (Mesima) exhibits significant anti-tumor activity against human hepatocellular carcinoma cells (HepG2); however, its molecular mechanism remains unknown..

OncologyImmune supportMetabolic healthLiver support

High relevance

Maitake · 2013 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Purification and characterization of a novel small-molecule polysaccharide from the Maitake medicinal mushroom Grifola frondosa (higher Basidiomycetes).

A novel small-molecule polysaccharide with a molecular mass of 2.6 kDa, was isolated from the culinary-medicinal Maitake mushroom Grifola frondosa. GFPS is composed of fucose, rhamnose, galactose, glucose, and mannose; galactose, glucose, and mannose were the dominant monosaccharides..

OncologyImmune supportMetabolic health

High relevance

King Oyster · 2013 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

Submerged cultivation of mycelium with high ergothioneine content from the culinary-medicinal king oyster mushroom Pleurotus eryngii (higher Basidiomycetes) and its composition.

The culinary-medicinal king oyster mushroom, Pleurotus eryngii, was used to produce mycelia with high ergothioneine content using a one-factor-at-a-time method. The optimal culture conditions for mycelia harvested at day 14 were 25°C, 10% inoculation rate, 2% glucose, 0.5% yeast extract, and no adjustment to the….

Metabolic health

High relevance

Almond Mushroom · 2012 · Research Support, Non U.S. Gov'T · In vivo (Athens, Greece)

Evaluation of genotoxicity and subclinical toxicity of Agaricus blazei Murrill in the Ames test and in histopathological and biochemical analysis.

This study was conducted in order to assess the safety and tolerability of Agaricus blazei Murrill (ABM) in general toxicological studies by Ames tests in vitro and in 28-day feeding toxicity experiments..

Cognition & nervesMetabolic healthGut & microbiomeLiver support

High relevance

Shiitake · 2012 · Research Support, Non U.S. Gov'T · Journal of microbiology (Seoul, Korea)

Immunoprophylactic effects of shiitake mushroom (Lentinula edodes) against Bordetella bronchiseptica in mice.

Antimicrobials are used as feed additives to improve growth performance and to prevent subclinical disease challenge in industrial animals. However, these drugs can lead to the development of resistant strains of bacteria.

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Reishi · 2012 · Book · journal metadata

Lingzhi, Reishi

Metadata-grounded summary: This book indexes research on Ganoderma lucidum in 2012. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

OncologyImmune supportMetabolic healthLiver support

High relevance

Enoki · 2012 · Research Support, Non U.S. Gov'T · Zeitschrift fur Naturforschung. C, Journal of biosciences

Optimization of soluble organic selenium accumulation during fermentation of Flammulina velutipes mycelia.

Selenium is an essential nutrient with diverse physiological functions, and soluble organic selenium (SOS) sources have a higher bioavailability than inorganic selenium sources..

Metabolic health

High relevance

Chaga · 2012 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Orally administered aqueous extract of Inonotus obliquus ameliorates acute inflammation in dextran sulfate sodium (DSS)-induced colitis in mice.

ETHNOPHARMACOLOGICAL RELEVANCE: Chaga mushroom (Inonotus obliquus) has been used in folk medicine to treat several disorders through its various biological functions. I..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Niu-Chang-Chih · 2011 · Research Support, Non U.S. Gov'T · Sheng wu gong cheng xue bao = Chinese journal of biotechnology

[Medium optimization for mycelia production of Antrodia camphorata based on artificial neural network-genetic algorithm].

To illustrate the complex fermentation process of submerged culture of Antrodia camphorata ATCC 200183, we observed the morphology change of this filamentous fungus..

Metabolic health

High relevance

Yellow Morel · 2011 · English Abstract · Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

[Optimization of culture conditions for production of extracellular polysaccharides by Morchella esculenta].

OBJECTIVE: To optimize the conditions for exopolysaccharides (EPS) production by Morchella esculenta GIM 5.69. METHODS: A Plackett-Burman design was used to evaluate the effects of variables factors..

Immune supportMetabolic health

High relevance

Chaga · 2011 · Research Support, Non U.S. Gov'T · Phytochemical analysis: PCA

Analysis of antioxidant metabolites by solvent extraction from sclerotia of Inonotus obliquus (Chaga).

INTRODUCTION: The sclerotia of Inonotus obliquus (Chaga) are effective therapeutic agents to treat several human malignant tumours and other diseases without unacceptable toxic side-effects. OBJECTIVE: To investigate solvent effects on metabolic profiles and antioxidant activities of extracts of Chaga..

OncologyImmune supportMetabolic health

High relevance

Mesima · 2011 · Patent · journal metadata

COMPOSITION FOR PREVENTING OR TREATING ATOPIC DERMATITIS AND ALLERGY-RELATED DISEASES COMPRISING FERMENTED PHELLINUS LINTEUS EXTRACT

PURPOSE: A composition containing fermented phellinus linteus extract is provided to effectively prevent or treat allergic dermatitis-associated disease. CONSTITUTION: A composition for preventing or treating allergic dermatitis-associated disease contains fermented phellinus linteus extract and pahrmacetuically….

Metabolic healthGut & microbiomeSkin & hydration

High relevance

Chaga · 2011 · Research Support, Non U.S. Gov'T · Journal of industrial microbiology & biotechnology

Enhancement of exo-polysaccharide production and antioxidant activity in submerged cultures of Inonotus obliquus by lignocellulose decomposition.

We reported that lignocellulose decomposition can be used to facilitate the production of bioactive polysaccharides from submerged culture of Inonotus obliquus. Exo-polysaccharide (EPS) production and antioxidant activity by Inonotus obliquus was enhanced by employing lignocellulose decomposition in a corn….

Immune supportMetabolic health

High relevance

Chaga · 2011 · Research Support, Non U.S. Gov'T · International journal of medicinal mushrooms

In vitro antitumor activity and structure characterization of ethanol extracts from wild and cultivated Chaga medicinal mushroom, Inonotus obliquus (Pers.:Fr.) Pilát (Aphyllophoromycetideae).

Inonotus obliquus (Pers.:Fr.) Pilát has been traditionally used as a folk remedy for treatment of cancers, cardiovascular disease and diabetes in Russia, Poland, and most of the Baltic countries, but natural reserves of this fungus have nearly been exhausted..

OncologyMetabolic health

High relevance

Chaga · 2011 · Research Support, Non U.S. Gov'T · Phytochemical analysis: PCA

Rapid isolation and purification of inotodiol and trametenolic acid from Inonotus obliquus by high-speed counter-current chromatography with evaporative light scatting detection.

INTRODUCTION: In Eastern Europe, especially Russia, the fruiting body of Inonotus obliquus has been used as a folk medicine for cancer since the sixteenth or seventeenth century. Inotodiol and trametenolic acid are considered to be the main bioactive compounds of the fruiting body of the mushroom..

OncologyEnergy & fatigueMetabolic healthRespiratory

High relevance

Niu-Chang-Chih · 2011 · Patent · journal metadata

USE OF ANTRODIA CAMPHORATA FOR TREATING DISEASES

The present invention relates to the use of antrodia camphorata in the treatment of skin conditions, allergic rhinitis, diabetes mellitus and its complications, cancer cachexia, hypercholesterolemia, gout in a subject in need of such treatment..

OncologyMetabolic healthSkin & hydration

High relevance

Turkey Tail · 2010 · Research Support, Non U.S. Gov'T · Water science and technology: a journal of the International Association on Water Pollution Research

Effect of glucose on enzyme activity and color removal by Trametes versicolor for high strength landfill leachate.

This research was carried out to study the treatment of landfill leachate by immobilized Trametes versicolor BCC 8725. Leachate was collected from Nonthaburi disposal site of Thailand from a pipe as discharged from landfill to the stabilization pond..

Energy & fatigueMetabolic health

High relevance

Chaga · 2010 · Comparative Study · Journal of food science

Effects of ultrasonic treatment on the physicochemical properties and DPPH radical scavenging activity of polysaccharides from mushroom Inonotus obliquus.

UNLABELLED: An ultrasonic technique was employed to extract polysaccharides from Inonotus obliquus (UPS). The effects of ultrasonic conditions on the recovery and 1, 1-diphenyl -2-picrylhydrazyl (DPPH) radical scavenging activity of UPS were evaluated..

OncologyImmune supportMetabolic health

High relevance

Chaga · 2010 · Research Support, Non U.S. Gov'T · Phytotherapy research: PTR

Extract of Chaga mushroom (Inonotus obliquus) stimulates 3T3-L1 adipocyte differentiation.

Chaga mushroom (Inonotus obliquus) has long been used as a folk medicine due to its numerous biological functions such as antibacterial, antiallergic, antiinflammatory and antioxidative activities. In the present study, it was found that the I..

Immune supportMetabolic health

High relevance

Chaga · 2010 · Patent · journal metadata

Total triterpenoid extract of inonotus obliquus with hypoglycemic function and pharmaceutical preparation thereof

The invention discloses a total triterpenoid extract of inonotus obliquus with a hypoglycemic function, which is prepared through the following steps: (1) crushing and sieving inonotus obliquus, adding ethanol aqueous solution for immersion, carrying out ultrasonic extraction, separating the supernatant, and….

Metabolic health

High relevance

Lion's Mane · 2010 · Research Support, Non U.S. Gov'T · Bioscience, biotechnology, and biochemistry

Yamabushitake Mushroom (Hericium erinaceus) Improved Lipid Metabolism in Mice Fed a High-Fat Diet

The effects of dietary Yamabushitake mushroom (Hericium erinaceus) on lipid metabolism were examined. C57BL/6J mice were fed a high-fat diet containing hot-water extract (HW-E) and an ethanol extract (EtOH-E) of Yamabushitake mushroom..

Metabolic healthLiver support

High relevance

Zhu Ling · 2009 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Bioactivity-directed isolation, identification of diuretic compounds from Polyporus umbellatus.

AIM OF THE STUDY: Polyporus umbellatus is a fungus used as a diuretic medicine. The objective of this study was to isolate and elucidate the diuretic constituents of n-hexane, ethyl acetate, n-butanol and water extracts of Polyporus umbellatus and to evaluate their diuretic activity..

Metabolic health

High relevance

Chaga · 2009 · Patent · journal metadata

Formulating method of yield nutrient fluid for inonotus obliquus cultivation

The invention discloses a preparation method of nutrient fluid used for accelerating the growing speed of sclerotia and increasing the density of functional components in the sclerotia after spraying during the sclerotia forming stage of artificially cultivating inonotus obliquus which belongs to medicinal fungi..

Metabolic health

High relevance

Mesima · 2009 · Patent · journal metadata

MEDICAL RED GINSENG CULTURED WITH PHELLINUS LINTEUS MYCELIUM AND CORDYCEPS MILLITARIS MYCELIUM

A medicinal red ginseng containing a Phellinus Linteus mycelium and Cordyceps millitaris mycelium is provided to have immunomodulation enhancement, blood pressure relieve, cholesterol lowering, and antioxidation..

Immune supportMetabolic health

High relevance

Chaga · 2009 · Patent · journal metadata

Preparation method for inonotus obliquus mother seed culture medium

The invention discloses a method for preparing mother culture medium of medicinal fungus inonotus obliquus. The medium is made from raw materials, such as birch sawdust juice, maltose, glucose, peptone, glutamic acid and agar gel..

Metabolic health

High relevance

Mesima · 2009 · Patent · journal metadata

PRODUCTS FOR PROCESSING CONTAING BONE STRENGTH COMPONENTS USING EXTRACTS FROM PHELLINUS LINTEUS AND METHOD THEREOF

A product containing an ingredient for improving bone density using a Phellinus linteus extract is provided to improve solubility of the ingredient and absorbility in to a body..

Metabolic health

High relevance

Chaga · 2009 · Research Support, Non U.S. Gov'T · Se pu = Chinese journal of chromatography

Quantitative determination of steroids in the fruiting bodies and submerged-cultured mycelia of Inonotus obliquus.

This study describes the method of quantitative determination of betulin, ergosterol, cholesterol, lanosterol, stigmasterol and sitosterol in the fruiting bodies and submerged-cultured mycelia of Inonotus obliquus. A high performance liquid chromatographic (HPLC) method was applied to separate these steroids..

Energy & fatigueMetabolic health

High relevance

Mesima · 2008 · Patent · journal metadata

A MANUFACTURING PROCESS OF FUNCTIONAL CANDY INCLUDING PHELLINUS LINTEUS EXTRACT AND A FUNCTIONAL CANDY MADE BY ITS MANUFACTURING PROCESS

A preparation method of a functional candy including a Phellinus linteus extract, and the functional candy are provided to enable anyone to easily take Phellinus linteus and enhance immunity..

Immune supportMetabolic health

High relevance

Maitake · 2008 · Research Support, Non U.S. Gov'T · Nutrition research (New York, N.Y.)

Antiatherosclerotic effect of the edible mushrooms Pleurotus eryngii (Eringi), Grifola frondosa (Maitake), and Hypsizygus marmoreus (Bunashimeji) in apolipoprotein E-deficient mice.

In the present study, we examined the antiatherosclerotic effects of 3 edible mushrooms, Pleurotus eryngii (Eringi), Grifola frondosa (Maitake), and Hypsizygus marmoreus (Bunashimeji), in atherosclerosis-susceptible C57BL/6J, apolipoprotein E-deficient (apoE(-/-)) mice..

Metabolic health

High relevance

Chaga · 2008 · Comparative Study · Journal of ethnopharmacology

Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice.

AIM OF THE STUDY: The antihyperglycemic and antilipidperoxidative effects of the dry matter of culture broth (DMCB) of Inonotus obliquus were investigated. MATERIALS AND METHODS: The normal, glucose-induced hyperglycemic and alloxan-induced diabetic mice were used to evaluate the antihyperglycemic and….

Metabolic healthLiver support

High relevance

Maitake · 2008 · Patent · journal metadata

CONFECTIONERY CONTAINING GRIFOLA FRONDOSA AND PRODUCING METHOD THEREOF

A method of manufacturing confectionery containing Grifola frondosa by mixing Grifola frondosa powder, eggs, sugar and salt is provided to give confectionery with excellent effect on protecting the liver and to increase the palatability..

Immune supportMetabolic healthLiver support

High relevance

Snow Fungus · 2008 · Patent · journal metadata

CRUDE EXOPOLYSACCHARIDES PRODUCED FROM TREMELLA FUCIFORMIS MYCELLIUM HAVING HYPOGLYCEMIC ACTIVITY AND PREPARATION METHOD THEREOF

This invention relates to the crude exopolysaccharides produced from Tremella fuciformis mycellium having hypoglycemic activity and preparation method thereof. In case type II diabetic model mice (ob/ob) are, treated with the exopolysaccharides produced from Tremella fuciformis mycellium, the plasma glucose levels in….

Immune supportMetabolic health

High relevance

Snow Fungus · 2008 · Patent · journal metadata

HYPOGLYCEMIC EXOPOLYSACCHARIDES FROM TREMELLA FUCIFORMIS MYCELLIUM AND A PREPARATION METHOD THEREOF

An exopolysaccharide obtained from Tremella fuciformis mycelium is provided to lower glucose content in plasma significantly and reduce lipid in blood when administered to a type 2 diabetic mouse, thereby controlling blood sugar of a diabetic patient and improving hyperlipidemia caused by obesity..

Immune supportMetabolic health

High relevance

Wood Ear · 2008 · Patent · journal metadata

MYCELIA AND FRUITING BODIES OF AURICULARIA AURICULA-JUDAE HAVING HYPOLIPIDEMIC EFFECT AND METHOD FOR PREPARING THE SAME

Mycelia and fruiting bodies of Auricularia auricula-judae are provided to show excellent hypolipidemic effect, thereby being effective for treating hyperlipidemia and preventing atherosclerosis..

Metabolic health

High relevance

Maitake · 2008 · Research Support, Non U.S. Gov'T · The Journal of pharmacy and pharmacology

Oral administration of submerged cultivated Grifola frondosa enhances phagocytic activity in normal mice.

Grifola frondosa fruiting body (Maitake) has been used as a dietary supplement due to its antitumour and immunomodulatory properties. The aim of this study was to evaluate the immunomodulatory effects of orally administered submerged cultivated G..

OncologyImmune supportMetabolic health

High relevance

Mesima · 2008 · Patent · journal metadata

Phellinus linteus mycelia active glucoprotein and use thereof and preparation

The invention discloses a submerged fermentation phellinus linteus mycelium glycoprotein, a usage and a separation extraction preparation method thereof, the complex is the complex of heteropolysaccharide and protein, wherein, the content of the heteropolysaccharide is 15 to 20 percent, and the heteropolysaccharide is….

Immune supportMetabolic health

High relevance

Mesima · 2008 · Patent · journal metadata

PHELLINUS LINTEUS VINEGAR HAVING AN ANTI-HYPERTENSION ACTIVITY

Phellinus linteus vinegar having the anti-hypertension activity is provided to inhibit production of angiotensin II and dissociation of bradykinin by inhibiting activity of angiotensin converting enzyme and reduce blood pressure by using Acetobacter aceti having high acetic acid-producing activity..

Metabolic health