MycoData

The prevention of postprandial hyperglycemia and diabetic complications is crucial for diabetes management. Inhibition of α-glucosidase to slow carbohydrate metabolism is a strategy to alleviate postprandial hyperglycemia..

Immune supportMetabolic health

High relevance

Chaga · 2022 · Journal Article · European journal of pharmacology

Inonotus obliquus and its bioactive compounds alleviate non-alcoholic fatty liver disease via regulating FXR/SHP/SREBP-1c axis.

Non-alcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease worldwide. However, there is still lack of specific drugs for treating NAFLD in clinic..

Metabolic healthLiver support

High relevance

Reishi · 2022 · Research Article · Journal of fungi (Basel, Switzerland)

Integrated Transcriptomics and Nontargeted Metabolomics Analysis Reveal Key Metabolic Pathways in Ganoderma lucidum in Response to Ethylene.

Ganoderic acid (GA) is an important secondary metabolite of Ganoderma lucidum with a diverse array of pharmacological properties. In this study, we found that exogenous ethylene increased the production of endogenous ethylene and ganoderic acid in G.

Metabolic health

High relevance

Oyster Mushroom · 2022 · Journal Article · Environmental pollution (Barking, Essex: 1987)

Integration of transcriptomic and proteomic reveals the toxicological molecular mechanisms of decabromodiphenyl ethane (DBDPE) on Pleurotus ostreatus.

Decabromodiphenyl ethane (DBDPE), as one of the most widely used new brominated flame retardants (NBFRs), can pose a potential threat to human health and the environment. An integrated transcriptome and proteome was performed for investigating the toxicological molecular mechanisms of Pleurotus ostreatus (P..

Metabolic health

High relevance

Snow Fungus · 2022 · Journal Article · Food Hydrocolloids

Interaction between potato starch and Tremella fuciformis polysaccharide

In order to elucidate the mechanism of interaction between Tremella fuciformis polysaccharide (TP) and potato starch (PS), PS-TP composites with different concentrations of TP were prepared, and their physicochemical properties, in vitro digestibility characteristic and microstructure were investigated..

Immune supportMetabolic healthGut & microbiome

High relevance

Shiitake · 2022 · Research Article · Journal of lasers in medical sciences

Introducing Protein Homeostasis and Glycogen Synthesis as Two Targets of Blue Light Radiation in Lentinula edodes.

Introduction: There are documents about the biological effects of blue light radiation on different organisms. An understanding of the molecular mechanism of radiation effects on biological samples is an important event which has attracted researchers' attention..

Energy & fatigue

High relevance

Yellow Morel · 2022 · Journal Article · Archives of microbiology

Investigation of Morchella esculenta and Morchella conica for their antibacterial potential against methicillin-susceptible Staphylococcus aureus, methicillin-resistant Staphylococcus aureus and Streptococcus pyogenes.

Antimicrobial resistance is an alarming problem, especially due to emergence of methicillin-resistance Staphylococcus aureus (MRSA). World Health Organization (WHO) has already listed MRSA as a top priority pathogen for the development of novel antibacterial agents..

Energy & fatigueGut & microbiome

High relevance

Snow Fungus · 2022 · Journal Article · Journal of food processing and preservation

Investigation on the effects of drying methods on the structure and antioxidant activity of Tremella fuciformis polysaccharides using asymmetrical flow field‐flow fractionation

Polysaccharide is an important bioactive component in Tremella fuciformis (T. fuciformis).

Immune support

High relevance

Oyster Mushroom · 2022 · Journal Article · Environmental pollution (Barking, Essex: 1987)

Laccase production by Pleurotus ostreatus using cassava waste and its application in remediation of phenolic and polycyclic aromatic hydrocarbon-contaminated lignocellulosic biorefinery wastewater.

The treatment of contaminants from lignocellulosic biorefinery effluent has recently been identified as a unique challenge. This study focuses on removing phenolic contaminants and polycyclic aromatic hydrocarbons (PAHs) from lignocellulosic biorefinery wastewater (BRW) applying a laccase-assisted approach..

High relevance

Reishi · 2022 · Journal Article · Phytochemistry

Lanostane triterpenoids from Ganoderma lucidum and their inhibitory effects against FAAH.

Ganoderma lucidum is a famous edible and medicinal fungus. Through a bioactive phytochemical investigation of the ethanolic extracts of the fruiting bodies of G.

OncologyImmune supportCognition & nerves

High relevance

Reishi · 2022 · Journal Article · Phytochemistry

Lanostane-type triterpenoids from the mycelial mat of Ganoderma lucidum and their hepatoprotective activities.

Ganoderma lucidum (G. lucidum), a well-known Polyporaceae family fungus, is valued for its edibility and medicinal properties.

Immune supportLiver support

High relevance

Oyster Mushroom · 2022 · Research Article · Journal of agricultural and food chemistry

LC/MS Q-TOF Metabolomic Investigation of Amino Acids and Dipeptides in Pleurotus ostreatus Grown on Different Substrates.

The well-established correlation between diet and health arouses great interest in seeking new health-promoting functional foods that may contribute to improving health and well-being..

High relevance

Shiitake · 2022 · Journal Article · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Lentinula edodes extract increases goblet cell number and Muc2 expression in an intestinal inflammatory model of Trichinella spiralis infection.

AHCC® is a standardized extract of cultured mushroom (Lentinula edodes) mycelia with a wide variety of therapeutic effects including anti-inflammatory, antitumor and antiviral effects. Trichinellosis, a food-borne parasitic zoonosis is caused by the nematode Trichinella spp..

OncologyImmune supportGut & microbiomeRespiratory

High relevance

Shiitake · 2022 · Journal Article · Arquivos de gastroenterologia

LENTINULA EDODES POLYSACCHARIDES SUPPRESSED PRO-INFLAMMATORY CYTOKINES EXPRESSION AND COLITIS IN MICE.

BACKGROUND: Polysaccharides from edible mushrooms possess immunomodulatory, anti-inflammatory, and anti-tumor activities. Recent studies indicated that necroptosis plays a role in the pathogenesis of inflammatory diseases and mediates increased expression of inflammatory cytokines..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Shiitake · 2022 · Research Article · Antioxidants (Basel, Switzerland)

Lentinula edodes, a Novel Source of Polysaccharides with Antioxidant Power.

The fruiting bodies of edible mushrooms represent an important source of biologically active polysaccharides. In this study, Lentinula edodes crude polysaccharides (LECP) were extracted in hot water, and their antioxidant and antiradical activities were investigated..

Immune supportMetabolic health

High relevance

Oyster Mushroom · 2022 · Research Article · Frontiers in microbiology

Ligninolytic characteristics of Pleurotus ostreatus cultivated in cotton stalk media.

Biodelignification is widely regarded as a low-efficiency process because it is usually slow and difficult to control. To improve its efficiency and understand its mechanism, the present study analyzed the delignification characteristics of Pleurotus ostreatus grown on a cotton stalk medium..

High relevance

Oyster Mushroom · 2022 · Journal Article · Food research international (Ottawa, Ont.)

Lipidomic profiling of Pleurotus ostreatus by LC/MS Q-TOF analysis.

In this paper, for the first time a lipidomic analysis on Pleurotus ostreatus species was performed by liquid chromatography quadrupole time-of-flight mass spectrometry (LC/MS Q-TOF). Twenty-seven lipid classes, including polar and non-polar lipid classes, were detected..

Cognition & nervesEnergy & fatigue

High relevance

Cordyceps · 2022 · Research Article · Frontiers in microbiology

Medium optimization for high mycelial soluble protein content of Ophiocordyceps sinensis using response surface methodology.

Ophiocordyceps sinensis is widely utilized due to its pharmaceutical value. Mycelial protein forms a key active component of O.

Metabolic health

High relevance

Reishi · 2022 · Journal Article · Fitoterapia

Meroterpenoids with a large conjugated system from Ganoderma lucidum and their inhibitory activities against renal fibrosis.

Baoslingzhines A-E (1-5), five new meroterpenoids were isolated from the fruiting bodies of Ganoderma lucidum. The structures including their absolute configurations were characterized by using spectroscopic and computational methods..

Skin & hydration

High relevance

Reishi · 2022 · Journal Article · International journal of biological macromolecules

Microwave-assisted degradation of β-D-glucan from Ganoderma lucidum and the structural and immunoregulatory properties of oligosaccharide fractions.

Microwave-assisted degradation of β-(1 → 3,1 → 6)-D-glucan from Ganoderma lucidum and correlated immunoregulatory activities were investigated in this study. The optimal temperature and degradation time for microwave hydrothermal hydrolysis were 140 °C and 40 min, respectively..

Immune supportMetabolic health

High relevance

Shiitake · 2022 · Research Article · Mycobiology

Mitochondrial Effects on the Physiological Characteristics of Lentinula edodes.

In the mating of filamentous basidiomycetes, dikaryotic mycelia are generated through the reciprocal movement of nuclei to a monokaryotic cytoplasm where a nucleus of compatible mating type resides, resulting in the establishment of two different dikaryotic strains having the same nuclei but different mitochondria..

Energy & fatigue

High relevance

Oyster Mushroom · 2022 · Research Article · Microbial cell factories

Mnsod1 promotes the development of Pleurotus ostreatus and enhances the tolerance of mycelia to heat stress.

BACKGROUND: Superoxide dismutases (SODs, EC 1.15.1.1) are defense proteins that can be used as sweepers to clear reactive oxygen species (ROS). They have been widely studied in the plant.

Energy & fatigue

High relevance

Snow Fungus · 2022 · Journal Article · Food research international (Ottawa, Ont.)

Moisture and caking resistant Tremella fuciformis polysaccharides microcapsules with hypoglycemic activity

Tremella fuciformis polysaccharides (TPs) have attracted extensive attention as functional food constituents due to their bioactivity. However, β-D-glucan obtained from TPs is readily degraded by oxidation and easy to absorb water and agglomerate..

Immune supportMetabolic health

High relevance

Yellow Morel · 2022 · Research Article · Frontiers in nutrition

Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model.

Type 2 diabetes mellitus (T2DM) is a health issue that causes serious worldwide economic problems. It has previously been reported that natural polysaccharides have been studied with regard to regulating the gut microbiota, which plays an important role in T2DM..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Yellow Morel · 2022 · Research Article · AMB Express

Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota.

Edible mushrooms have now been suggested as promising sources of biological functional ingredients and are the subject of the most recent nutrition research and novel functional foods. Polysaccharides from mushrooms exhibit impressive biological effects, notably against obesity..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Reishi · 2022 · Research Article · Polymers

Mushroom β-Glucan Recovered from Antler-Type Fruiting Body of Ganoderma lucidum by Enzymatic Process and Its Potential Biological Activities for Cosmeceutical Applications.

Mushrooms are incredibly valuable macro fungi that are an important and integral part of the ecosystem. In addition to being used as cuisine, mushrooms have been used for medicinal purposes for many centuries..

Skin & hydration

High relevance

Yellow Morel · 2022 · Journal Article · Food research international (Ottawa, Ont.)

Mycochemical profile and health-promoting effects of morel mushroom Morchella esculenta (L.) – A review

Mushrooms have been well known for centuries in traditional Chinese medicine for their medicinal properties. Morchella esculenta (L.) Pers.

OncologyImmune supportMetabolic healthLiver support

High relevance

Reishi · 2022 · Journal Article · Microbiological research

NAD+-dependent Glsirt1 has a key role on secondary metabolism in Ganoderma lucidum.

Nicotinamide adenine dinucleotide (NAD+) is an important intracellular metabolite that is involved in different cel1lular processes. Glnmnat is the key enzyme that can affect intracellular NAD+ content..

Metabolic health

High relevance

Lion's Mane · 2022 · Journal Article · Journal of agricultural and food chemistry

Natural Compound 2-Chloro-1,3-dimethoxy-5-methylbenzene, Isolated from Hericium Erinaceus, Inhibits Fungal Growth by Disrupting Membranes and Triggering Apoptosis.

In this study, 2-chloro-1,3-dimethoxy-5-methylbenzene (CDM), a natural product with anti-Candida albicans activity, was discovered from the Hericium erinaceus mycelium. The minimum inhibitory concentration of CDM was 62.5 μg/mL..

OncologyEnergy & fatigue

High relevance

Turkey Tail · 2022 · Journal Article · Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering

Neomycin removal using the white rot fungus Trametes versicolor.

The presence of antibiotic resistance genes in wastewater treatment plants (WWTPs), and in river and lake recipients show the need to develop new antibiotic removal strategies..

High relevance

Maitake · 2022 · Journal Article · Trends in food science & technology

New light on Grifola frondosa polysaccharides as biological response modifiers

Grifola frondosa is a valuable fungus with high health and medicinal value, and it plays an important role in the treatment of diseases as traditional Chinese medicine. Among them, the active ingredient that plays the main function was polysaccharides..

Immune support

High relevance

Oyster Mushroom · 2022 · Research Article · Journal of fungi (Basel, Switzerland)

Nitric Oxide Negatively Regulates the Rapid Formation of Pleurotus ostreatus Primordia by Inhibiting the Mitochondrial aco Gene.

Nitric oxide (NO) is as a signaling molecule that participates in the regulation of plant development and in a number of physiological processes. However, the function and regulatory pathway of NO in the growth and development of edible mushrooms are still unknown..

Energy & fatigueRespiratory

High relevance

Reishi · 2022 · Research Article · Frontiers in pharmacology

Nontargeted metabolomics study and pharmacodynamic evaluation of bidirectional fermentation for Ganoderma lucidum with Marsdenia tenacissima.

Lung cancer is one of the malignant tumors with the fastest incidence rate and mortality growth and the greatest threat to human health and life. Marsdenia tenacissima is an antitumor of Chinese medicine..

OncologyRespiratory

High relevance

Yellow Morel · 2022 · Research Article · Foods (Basel, Switzerland)

Nutrition Profile and Animal-Tested Safety of Morchella esculenta Mycelia Produced by Fermentation in Bioreactors.

Morchella esculenta (ME), or "true" morel mushrooms, are one of the most expensive mushrooms. M.

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Oyster Mushroom · 2022 · Research Article · Bioresources and bioprocessing

Nutritional and antioxidant changes in lentils and quinoa through fungal solid-state fermentation with Pleurotus ostreatus.

Solid-state fermentation (SSF) may be a suitable bioprocess to produce protein-vegetal ingredients with increased nutritional and functional value. This study assessed changes in phenol content, antinutrient content, biomass production and protein production resulting from the metabolic activity of Pleurotus….

Metabolic health

High relevance

Enoki · 2022 · Journal Article · Industrial crops and products

Optimization of ultrasonic extraction of polysaccharides from Flammulina velutipes residue and its protective effect against heavy metal toxicity

The extraction process of polysaccharides from Flammulina velutipes residue (FVRP) was optimized by the single factor test and response surface methodology with the physical and chemical properties of FVRP determined..

Immune supportEnergy & fatigueMetabolic health

High relevance

Reishi · 2022 · Journal Article · International journal of biological macromolecules

Organic chromium derived from the chelation of Ganoderma lucidum polysaccharide and chromium (III) alleviates metabolic syndromes and intestinal microbiota dysbiosis induced by high-fat and high-fructose diet.

Organic chromium is of great interest and has become an important chromium supplement resource in recent years because of its low toxicity and easy absorption. In our previous study, we synthesized a novel organic chromium [GLP-Cr] through the chelation of Ganoderma lucidum polysaccharide and chromium (III)..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Chaga · 2022 · Journal Article · Natural product research

Phenolic compounds from the sclerotia of Inonotus obliquus.

Three phenolic compounds (±1 and 2) including a pair of new enantiomers were isolated from the sclerotia of Inonotus obliquus. Their structures were assigned by extensive spectroscopic analyses..

Cognition & nerves

High relevance

Reishi · 2022 · Research Article · Food chemistry: X

Physicochemical characteristics of Ganoderma lucidum oligosaccharide and its regulatory effect on intestinal flora in vitro fermentation.

This study explored the structure characteristics of an oligosaccharide from Ganoderma lucidum (GLO) and its regulatory functions on intestinal flora fermentation in vitro. GLO was extracted by ultrasonic-assisted enzymatic hydrolysis, and purified with a dextran gel column..

Gut & microbiome

High relevance

Snow Fungus · 2022 · Journal Article · International journal of biological macromolecules

Physicochemical properties and in vitro digestion behavior of a new bioactive Tremella fuciformis gum.

A new easy-dissolved Tremella fuciformis gum (TFG) from fruiting body was investigated in detail from three aspects: physicochemical characteristics, rheological behavior and in vitro digestion behavior..

Immune supportGut & microbiome

High relevance

Shiitake · 2022 · Journal Article · Applied microbiology and biotechnology

Physiological mechanisms by which gypsum increases the growth and yield of Lentinula edodes.

Lentinula edodes is one of the most important commercially cultivated edible mushrooms. It is well known that gypsum (CaSO4·2H2O) supplementation in sawdust medium increases the yield of L.

High relevance

Zhu Ling · 2022 · Journal Article · Phytomedicine: international journal of phytotherapy and phytopharmacology

Phytochemistry and bioactivities of the main constituents of Polyporus umbellatus (Pers.) Fries.

BACKGROUND: Edible fungi resources have good application prospects in the research and development of food, medicine, and health products. Polyporus umbellatus (Pers.) Fries, as a precious edible and medicinal fungus, has long been used by Chinese medicine to treat urinary systems and related kidney diseases..

OncologyImmune supportSkin & hydration

High relevance

Oyster Mushroom · 2022 · Research Article · Nutrients

Pleurotus Ostreatus Ameliorates Obesity by Modulating the Gut Microbiota in Obese Mice Induced by High-Fat Diet.

Pleurotus ostreatus (PO), a common edible mushroom, contains rich nutritional components with medicinal properties. To explore the effect of PO on ameliorating obesity and modulating the gut microbiota, we administered the mice with a low-fat diet or high-fat diet containing different dosages of PO (mass fraction: 0%,….

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Reishi · 2022 · Journal Article · Food & function

Polysaccharide from Ganoderma lucidum alleviates cognitive impairment in a mouse model of chronic cerebral hypoperfusion by regulating CD4+CD25+Foxp3+ regulatory T cells.

Ganoderma lucidum (G. lucidum) is a kind of edible and medicinal mushroom.

Immune supportCognition & nervesEnergy & fatigue

High relevance

Maitake · 2022 · Journal Article · The Journal of pharmacy and pharmacology

Polysaccharides of Grifola frondosa ameliorate oxidative stress and hypercholesterolaemia in hamsters fed a high-fat, high-cholesterol diet.

OBJECTIVES: This study was to evaluate the antioxidant and anti-hypercholesterolaemia activities of Grifola frondosa in hamsters fed a high-fat, high-cholesterol (HFHC) diet. METHODS: G..

Immune supportMetabolic healthLiver support

High relevance

Lion's Mane · 2022 · Research Article · Polymers

Preparation, Characterization and Gelation of a Fungal Nano Chitin Derived from Hericium erinaceus Residue.

Nano chitin is a promising biocompatible material with wide applications. In this work, a fungal-derived nano chitin was prepared from Hericium erinaceus residue via mineral/protein purification and subsequent TEMPO-mediated oxidation..

High relevance

Enoki · 2022 · Journal Article · Bioscience, biotechnology, and biochemistry

Production and properties of a laccase isozyme (FvLcc3) from the edible mushroom Flammulina velutipes, which is undetectable under the culture condition for fruiting body formation.

Extracellular laccase isozyme (FvLcc3) from the edible mushroom Flammulina velutipes was found to be undetectable under the culture condition for fruiting body formation. FvLcc3 was purified and determined to be an approximately 53-kDa monomeric protein..

High relevance

Maitake · 2022 · Journal Article · Journal of the science of food and agriculture

Purification and characterization of Se-enriched Grifola frondosa glycoprotein, and evaluating its amelioration effect on As3+ -induced immune toxicity.

BACKGROUND: Selenium (Se)-enriched glycoproteins have been a research highlight for the role of both Se and glycoproteins in immunoregulation. Arsenic (As) is a toxicant that is potentially toxic to the immune function and consequently to human health..

Immune supportEnergy & fatigue

High relevance

Maitake · 2022 · Journal Article · Journal of the science of food and agriculture

Purification and characterization of Se‐enriched Grifola frondosa glycoprotein, and evaluating its amelioration effect on As3+‐induced immune toxicity

BACKGROUND: Selenium (Se)‐enriched glycoproteins have been a research highlight for the role of both Se and glycoproteins in immunoregulation. Arsenic (As) is a toxicant that is potentially toxic to the immune function and consequently to human health..

Immune supportEnergy & fatigue

High relevance

Mesima · 2022 · Journal Article · Preparative biochemistry & biotechnology

Purification of polysaccharides from Phellinus linteus by using an aqueous two-phase system and evaluation of the physicochemical and antioxidant properties of polysaccharides in vitro.

In this study, Phellinus linteus polysaccharides (PLPS) and proteins were simultaneously separated from P. linteus mycelia by using an aqueous two-phase system (ATPS) based on choline chloride ([Chol]Cl)/K2HPO4, and the physicochemical and antioxidant properties of PLPS after ATPS extraction were evaluated..

Immune support