MycoData

BACKGROUND: Protection of the intellectual property (IP) rights on new crop varieties is important as it allows the breeding company or entity that produced the variety to earn back (part of) the investment. Infringement on the IP rights of mushroom varieties is not uncommon..

High relevance

Oyster Mushroom · 2025 · Preprint · journal metadata

Optimization of Substrate and Fermentation Conditions for Mycoprotein Production from Pleurotus ostreatus (Oyster Mushroom) Cultivated on Sugarcane Straw and Cassava Peels in Okitipupa, Nigeria

Mycoprotein, a sustainable protein source, can be produced from various substrates using fungi like Pleurotus ostreatus. This study optimized substrate and fermentation conditions for mycoprotein production from P.

High relevance

Oyster Mushroom · 2025 · Research Article · Foods (Basel, Switzerland)

Oyster Mushroom (Pleurotus ostreatus) and Okara Flour as Nutritional Enhancers in Wheat Biscuits: A Study on Storage Stability.

In response to the scarcity and high cost of wheat in Nigeria, this study investigates the potential of oyster mushroom (Pleurotus ostreatus) and okara flour to enhance the nutritional quality and storage stability of wheat biscuits..

High relevance

Oyster Mushroom · 2025 · Research Article · Journal of experimental pharmacology

Oyster Mushroom (Pleurotus ostreatus) Ethanolic Extract Inhibits Pparg Expression While Maintaining the Methylation of the Pparg Promoter During 3T3-L1 Adipocyte Differentiation.

PURPOSE: This study aims to provide new insights into the potential of oyster mushroom (Pleurotus ostreatus) ethanolic extract in preventing obesity through the inhibition of Pparg expression and modulation of methylation level on Pparg promoter during 3T3-L1 adipocyte differentiation..

Metabolic health

High relevance

Lion's Mane · 2025 · Journal Article · Journal of food science

pH-shifted synergistic ultrasound-modified extraction of Hericium erinaceus protein.

In this paper, we investigated the effects of different conditions on the extraction rate of Hericium erinaceus protein (HEP), determined the optimal extraction process for alkaline extraction of Hericium erinaceus (HE) protein, and explored the effects of ultrasound-assisted pH-shift treatment on HEP activity..

Metabolic health

High relevance

Reishi · 2025 · Journal Article · Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Pharmacokinetic and tissue distribution analysis of sporoderm-removed Ganoderma lucidum spore powder in rats.

Ganoderma lucidum (Lingzhi), a medicinal mushroom, is recognized for its broad pharmacological activities, including potential health and longevity benefits. Notably, several triterpenoids derived from its spores and fruiting body have demonstrated anti-inflammatory, anti-tumor, and immunomodulatory effects..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Oyster Mushroom · 2025 · Preprint · journal metadata

Phenotypic profiling, Comparative analysis of Nutritional compositions and Antioxidant potential of Pleurotus ostreatus (oyster mushroom) cultivated on Different Agricultural wastes

Oyster mushrooms (Pleurotus ostreatus) are a type of edible mushroom that has gained popularity worldwide due to its nutritional benefits, culinary value, and potential medicinal properties..

High relevance

Reishi · 2025 · Preprint · journal metadata

Phytochemical Analysis and Antimicrobial Activity of Ganoderma lucidum Against Selected Bacteria and Fungi of Medical Importance

Abstract Introduction: Ganoderma lucidum, a medicinal mushroom widely studied for its bioactive properties, holds promise for antimicrobial applications. This study aimed to identify G..

High relevance

Reishi · 2025 · Research Article · Scientific reports

Phytochemical analysis and antimicrobial activity of Ganoderma lucidum against selected bacteria and fungi of medical importance.

Ganoderma lucidum is a rapidly growing mushroom, wood-colonizing fungus belonging to the phylum Basidiomycota. G.

OncologyGut & microbiome

High relevance

King Oyster · 2025 · Research Article · Food science & nutrition

Pleurotus eryngii Culture Filtrate and Aqueous Extracts Alleviate Aflatoxin B1 Synthesis.

Mycotoxins in food and feed are a significant health risk, even more so than pesticides and synthetic waste. These toxic secondary metabolites are produced by various fungal species, particularly after fungal colonization of crops..

Immune supportGut & microbiomeLiver support

High relevance

King Oyster · 2025 · Research Article · Nutrients

Pleurotus eryngii Mushrooms Fermented with Human Fecal Microbiota Protect Intestinal Barrier Integrity: Immune Modulation and Signalling Pathways Counter Deoxycholic Acid-Induced Disruption in Healthy Colonic Tissue.

Background: This study explores the potential of the Pleurotus eryngii mushroom fermentation supernatant (FS-PEWS) as an intervention for mitigating sodium deoxycholate (SDC)-induced intestinal barrier dysfunction and inflammation..

Immune supportGut & microbiome

High relevance

King Oyster · 2025 · Research Article · Plants (Basel, Switzerland)

Pleurotus eryngii Stipe Base-Derived Carbon Dots Enhanced the Growth and Salt Tolerance of Tomato.

Soil salinity severely limits tomato growth by impairing photosynthesis and redox balance. Carbon dots (CDs) have emerged as promising nanomaterials to promote growth and enhance stress tolerance..

High relevance

King Oyster · 2025 · Journal Article · Food & function

Positive effect of a novel protein from Pleurotus eryngii on improving colitis: exploring potential mechanisms from the perspective of intestinal metabolism.

Pleurotus eryngii (P. eryngii) protein has demonstrated potential anti-inflammatory effects, but the specific mechanism has not been reported.

Immune supportMetabolic healthGut & microbiome

High relevance

Cordyceps · 2025 · Research Article · Journal of cosmetic dermatology

Potential Cosmetic Applications of the Combined Extract of Panax ginseng, Ganoderma lucidum, Cordyceps militaris, and Several Asian Plants.

OBJECTIVE: Although bioactive compounds from single herbs are extensively explored in cosmetics, the synergistic potential of herbal combinations remains understudied..

OncologyImmune supportEnergy & fatigueSkin & hydration

High relevance

Cordyceps · 2025 · Journal Article · International journal of medicinal mushrooms

Preparation and Characterization of a Novel Magnetic Molecularly Imprinted Polymer Capable of Isolating and Purifying Cordycepin from a Submerged Culture of the Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes).

In this work, magnetic molecularly imprinted polymer (MMIP) capable of selectively recognizing and adsorbing cordycepin was prepared. The MMIP was prepared using cordycepin as the template molecule, methacrylic acid and acrylamide as the functional monomer and ethylene glycol dimethacrylate as the crosslinker..

High relevance

Reishi · 2025 · Journal Article · Food Bioscience

Preparation of novel Ganoderma lucidum protein-derived bioactive peptides and their oxidation resistance, melanin synthesis inhibition and anti-inflammatory functions

As a key active component in Ganoderma lucidum, the preparation and biological activities of Ganoderma lucidum immunomodulatory protein (rFIP-glu) have been reported, but its deep utilization, such as the preparation of bioactive peptides, has not been explored..

Immune supportGut & microbiomeSkin & hydration

High relevance

King Oyster · 2025 · Journal Article · Food Hydrocolloids

Preparation of salt-free Pleurotus eryngii protein with enhanced colloidal stability and emulsifying properties by ceramic membrane filtration

Fungi proteins represent a potential alternative to animal proteins, which are regarded as a prospective source of edible proteins due to more sustainable and efficient cultivation of fungi..

High relevance

Enoki · 2025 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Prevalence and characterization of Listeria monocytogenes isolated from online market-purchased enoki mushrooms (Flammulina velutipes) in the Republic of Korea

The aim of this study was to characterize the microbiological quality of enoki mushrooms (Flammulina velutipes) commercially sold via online market retailers in the Republic of Korea and to identify the antibiotic susceptibility and genetic variability of Listeria monocytogenes isolates..

High relevance

Cordyceps · 2025 · Research Article · Current research in food science

Probiotic Levilactobacillus brevis GH1 from baijiu Daqu enhanced γ-aminobutyric acid and antioxidant ability in Cordyceps militaris fruiting body extract and brown rice beverage.

γ-Aminobutyric acid (GABA) is a functional amino acid with various physiological activities. Increasing the concentration of GABA in foods and enhancing dietary supplementation are important for health benefits.

Gut & microbiome

High relevance

Oyster Mushroom · 2025 · Research Article · Scientific reports

Production and biochemical characterization of Pleurotus ostreatus NRC 620 laccase and evaluation of its efficacy in apple juice clarification.

The highest activity of the Pleurotus ostreatus NRC620 laccase enzyme occurred in the broth of mushroom growth after 25 days of incubation at 28 °C and static conditions..

High relevance

King Oyster · 2025 · Research Article · Foods (Basel, Switzerland)

Production and Optimization of Anti-Aging Peptides from Pleurotus eryngii Mushroom Feet: Mechanistic Insights via Integrated Transcriptomics and Metabolomics.

This study established an optimized process for obtaining anti-aging peptides from Pleurotus eryngii mushroom feet (PEMFPeps). Using response surface methodology, high yields of protein (51.31 ± 3.00%) and peptides (48.71 ± 0.17% hydrolysis degree) were achieved..

Cognition & nervesEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Oyster Mushroom · 2025 · Review · International journal of molecular sciences

Production of β-Glucans by Pleurotus ostreatus: Cultivation and Genetic Background.

Pleurotus ostreatus is one of the most frequently cultivated mushroom species. It has attracted considerable attention not only because of its short cultivation time, but also because of the wide range of substrates on which it can be cultivated, such as lignocellulosic materials, synthetic polymers and wastewater..

High relevance

Oyster Mushroom · 2025 · Preprint · journal metadata

Productivity of Pleurotus ostreatus on lignocellulosic Rice Husk substrate supplemented with Sugar Industry Residual Biomass

ABSTRACT Substrate formulations based on Oryza sativa (rice) husk supplemented with sugar industry waste bagasse and Saccharum officinarum L. filter cake were used as an alternative substrate to cultivate mushrooms such as Pleurotus osteatrus, being essential the comparison of the productivity parameters carried out….

High relevance

Lion's Mane · 2025 · Research Article · Applied and environmental microbiology

Puerarin combined with Hericium erinaceus insoluble dietary fiber alleviates obesity induced by high-fat diet through regulating the glycerophospholipid metabolism pathway influenced by gut microbiota.

The purpose of this study was to evaluate the combined effects of puerarin (Pue) and insoluble dietary fiber from Hericium erinaceus (HEIDF) on obesity induced by a high-fat diet (HFD) in mice, focusing on their effects on lipid and glucose metabolism, gut microbiota (GM), and serum metabolites..

Metabolic healthGut & microbiomeLiver support

High relevance

Shiitake · 2025 · Journal Article · Virus genes

Rapid and visual detection of Lentinula edodes spherical virus using CRISPR/Cas12a-based RT-RPA.

Lentinula edodes (shiitake) is a globally important edible mushroom, but viral infections can hinder mycelial growth, reduce yield, and degrade quality, leading to economic losses. This study examined viral infections in L.

Respiratory

High relevance

Snow Fungus · 2025 · Review · Frontiers in nutrition

Recent advances in polysaccharides from Tremella fuciformis: isolation, structures, bioactivities and application.

Tremella fuciformis, commonly known as snow fungus, is a traditional edible and medicinal fungus widely used in Asian countries for centuries. Its main bioactive constituents, Tremella fuciformis polysaccharides (TFPs), have attracted considerable attention in both food and pharmaceutical industries due to their….

Immune supportMetabolic health

High relevance

Reishi · 2025 · Review · Pharmaceutics

Recent Advances in the Use of Ganoderma lucidum and Coriolus versicolor Mushrooms to Enhance the Anticancer Efficacy of EGFR-Targeted Drugs in Lung Cancer.

Lung cancer is the leading cause of cancer-related deaths worldwide. Non-small cell lung cancer (NSCLC) is the major subtype, accounting for more than 85% of all lung cancer cases..

OncologyImmune supportSkin & hydrationRespiratory

High relevance

Reishi · 2025 · Review · Natural product research

Reishi Mushroom (Ganoderma lucidum): pharmacology of a potent healer in traditional Chinese medicine.

Reishi mushroom, also known as Lingzhi or Ganoderma lucidum, is a widely studied macrofungus in Traditional Chinese Medicine, revered for over two millennia in Asia..

OncologyImmune supportCognition & nervesMetabolic health

High relevance

King Oyster · 2025 · Research Article · Bioresources and bioprocessing

Revitalizing Pleurotus eryngii polysaccharides: gamma irradiation boosts antidiabetic and antioxidant potential.

Polysaccharides derived from Pleurotus eryngii possess various bioactive properties, including antioxidant, antidiabetic, anti-inflammatory, and immunomodulatory effects. In this study, polysaccharides were extracted from P..

Immune supportMetabolic healthLiver support

High relevance

Shiitake · 2025 · Research Article · Scientific reports

Safety assessment and in vitro cytotoxicity profiling of fruiting bodies from Lentinula edodes (shiitake) strains in HeLa and MCF-7 cell lines.

Medicinal mushrooms offer diverse therapeutic benefits, but proper administration is crucial to avoid long-term health issues linked to fungal toxicity. This study evaluated the safety and in vitro cytotoxic potential of Lentinula edodes (shiitake) mushrooms for broader use in food and health supplements..

OncologyImmune supportMetabolic health

High relevance

Reishi · 2025 · Research Article · Scientific reports

Selected strains of the Ganoderma lucidum complex from Finnish forests have excellent broadly acting antiviral properties.

Broadly acting antivirals are needed to complement vaccines in present and future pandemics and outbreaks as safe and sustainable tools for combating virus infections..

Respiratory

High relevance

Cordyceps · 2025 · Research Article · Food science & nutrition

Selenium-Enriched Cordyceps militaris Polysaccharides Alleviate Insulin Resistance in HepG2 Cells by Regulating the PI3K/AKT/GLUT4 Signaling Pathway.

Metal ion-rich Cordyceps militaris polysaccharides (CMP) are obtained by biotransformation and chemical synthesis. The physicochemical properties and bioactivity of selenium-enriched CMP (Se-CMP) obtained using biotransformation remain unclear.

Immune supportEnergy & fatigueMetabolic health

High relevance

Oyster Mushroom · 2025 · Journal Article · Journal of food science

Simultaneous extraction and purification of polysaccharides and proteins from Pleurotus ostreatus using an aqueous two-phase system.

Pleurotus ostreatus is a nutrient-dense edible fungus renowned for its delicate texture, appealing flavor, and numerous potential health benefits. Simultaneous extraction within the framework of food resource processing facilitates the concurrent isolation and analysis of multiple target compounds..

Immune supportEnergy & fatigueMetabolic health

High relevance

Reishi · 2025 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Solid-state fermentation with Ganoderma lucidum improves nutritional quality and processing characteristics of wheat (Triticum aestivum L.)

Whole wheat is nutrient-rich and contains bioactive substances, but its poor processing qualities and rough taste make it less appealing to consumers. Recently, microbial fermentation has been widely used to improve cereal nutrition and processing properties..

High relevance

Cordyceps · 2025 · Research Article · Foods (Basel, Switzerland)

Soy Sauce Fermentation with Cordyceps militaris: Process Optimization and Functional Profiling.

This study presents the development and optimization of a functional soy sauce fermented with Cordyceps militaris (C. militaris), a medicinal fungus known for its high cordycepin and polysaccharide content.

Immune support

High relevance

Reishi · 2025 · Research Article · Frontiers in pharmacology

Sporoderm-removed ganoderma lucidum spore powder (S-GLSP) alleviates neuroinflammation injury by regulating microglial polarization through inhibition of NLRP3 inflammasome activation.

INTRODUCTION: Sporoderm-Removed Ganoderma lucidum Spore Powder (S-GLSP), derived from the spores of the medically valued fungus Ganoderma lucidum, exhibits diverse pharmacological activities and shows considerable potential in the treatment of Alzheimer's disease (AD)..

Immune supportCognition & nerves

High relevance

Cordyceps · 2025 · Review · Antonie van Leeuwenhoek

Strain improvement of Cordyceps militaris for optimized bioactive metabolite biosynthesis: current progress and prospective approaches.

Cordyceps militaris is a rare and highly valued medicinal fungus that has attracted considerable attention due to its production of diverse bioactive compounds, including nucleosides such as cordycepin, polysaccharides, lovastatin, carotenoids, etc., all of which exhibit significant nutritional and therapeutic….

Immune supportMetabolic health

High relevance

Reishi · 2025 · Journal Article · Carbohydrate polymers

Structural and functional benefits of Ganoderma lucidum polysaccharides due to space mutagenesis

Ganoderma lucidum samples from space-mutated strains transported by China's “Shenzhou” recoverable satellites, along with traditionally cultivated counterparts, were selected for this study..

Immune supportMetabolic health

High relevance

Reishi · 2025 · Journal Article · Carbohydrate polymers

Structural and functional benefits of Ganoderma lucidum polysaccharides due to space mutagenesis.

Ganoderma lucidum samples from space-mutated strains transported by China's "Shenzhou" recoverable satellites, along with traditionally cultivated counterparts, were selected for this study..

Immune supportMetabolic health

High relevance

Reishi · 2025 · Journal Article · International journal of biological macromolecules

Structural characteristics of a heteropolysaccharide from Ganoderma lucidum and its protective effect against Alzheimer's disease via modulating the microbiota-gut-metabolomics.

Ganoderma lucidum is a traditional Chinese medicine used to treat Alzheimer's disease (AD), whose main active ingredient is polysaccharides. A heteropolysaccharide named GLPZ-1 was isolated from Ganoderma lucidum.

Immune supportCognition & nervesMetabolic healthGut & microbiome

High relevance

King Oyster · 2025 · Journal Article · International journal of biological macromolecules

Structural characteristics of Pleurotus eryngii polysaccharide and its protective mechanisms against mastitis in mice.

Mastitis, a common inflammatory condition in female mammals, increases the risk of breast cancer and causes substantial economic losses. Although antibiotics effectively treat mastitis, their overuse poses a threat to public health and safety..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Reishi · 2025 · Research Article · Scientific reports

Structural characteristics, sugar metabolizing enzyme activity and biological activity of Ganoderma lucidum polysaccharides at different growth stages.

The Ganoderma lucidum polysaccharides (GLPs) content, monosaccharide composition, molecular weight, sugar metabolism-related enzyme activities and in vitro antioxidant activities of Ganoderma lucidum fruiting body (GLFB) from cassava stalk cultivation at different growth stages (namely, differentiation stage, umbrella….

Immune supportMetabolic health

High relevance

King Oyster · 2025 · Journal Article · International journal of biological macromolecules

Structure and strain specificity for polysaccharides from king oyster mushroom (Pleurotus eryngii) fruiting bodies.

King oyster mushroom Pleurotus eryngii is cultivated worldwide for culinary and to improve human health. However, the potential of some Mediterranean representatives of this species is still not evaluated.

Immune support

High relevance

Turkey Tail · 2025 · Research Article · Microbial cell factories

Studies on the treatment of anaerobically digested sludge by white-rot fungi: evaluation of the effect of Phanerochaete chrysosporium and Trametes versicolor.

BACKGROUND: The composition of anaerobically digested sludge is inherently complex, enriched with structurally complex organic compounds and nitrogenous constituents, which are refractory to biodegradation. These characteristics limit the subsequent rational utilization of resources from anaerobically digested sludge..

Energy & fatigueGut & microbiomeSkin & hydration

High relevance

Oyster Mushroom · 2025 · Preprint · journal metadata

Substrate Formulation Effects on Pleurotus ostreatus Production and Nutritional Profile

This study compared the effects of using different lignocellulosic substrates on the growth, yield, and nutritional composition of Pleurotus ostreatus mushrooms. Three substrate formulas were investigated: a commercial/standard oyster formula (S), willow chips with cottonseed hulls (W+C), and willow chips alone (W)..

Energy & fatigueGut & microbiome

High relevance

Cordyceps · 2025 · Journal Article · International journal of medicinal mushrooms

Substrate Influence on Yield and Biometabolite Production in the Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes).

The present work was aimed at studying the effect of different substrates on growth and biometabolite production in Cordyceps militaris fruiting body. Of the seven substrates tested alone and in combination with brown rice, it was observed that the combination of pearl millet and brown rice showed the highest yield of….

High relevance

Chaga · 2025 · Journal Article · Journal of Chromatography A

Supercritical fluid-based protocol for the identification and quantitation of triterpenoids in commercial Inonotus obliquus (chaga) samples

Inonotus obliquus is a fungal pathogen that parasitizes the trunks of broadleaved tree species. The sclerotia of this fungus, so-called chaga, show a broad range of traditional and medicinal uses..

Immune supportEnergy & fatigueMetabolic health

High relevance

Chaga · 2025 · Journal Article · Journal of chromatography. A

Supercritical fluid-based protocol for the identification and quantitation of triterpenoids in commercial Inonotus obliquus (chaga) samples.

Inonotus obliquus is a fungal pathogen that parasitizes the trunks of broadleaved tree species. The sclerotia of this fungus, so-called chaga, show a broad range of traditional and medicinal uses..

Immune supportEnergy & fatigueMetabolic health

High relevance

Enoki · 2025 · Journal Article · Food Research International

Superiority of ultrasound-extracted Flammulina velutipes polysaccharides over hot water-extracted ones in mitigating colonic cell pyroptosis: Discoveries into modulation of NLRP3 pathway

Flammulina velutipes is a major edible fungus with abundant yield and mature industrial production technology. Its main functional component, Flammulina velutipes polysaccharide, has huge development and utilization value..

Immune supportGut & microbiome

High relevance

Enoki · 2025 · Journal Article · Food research international (Ottawa, Ont.)

Superiority of ultrasound-extracted Flammulina velutipes polysaccharides over hot water-extracted ones in mitigating colonic cell pyroptosis: Discoveries into modulation of NLRP3 pathway.

Immune supportGut & microbiome