MycoData
Medicinal fungi research database
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Liver support
Hepatoprotection, liver enzymes, toxin exposure, and hepatic injury literature.
Species records
Species record
Oyster Mushroom
Pleurotus ostreatus
- Studies
- 1,947
- Avg relevance
- 53
- Latest
- 2026
Species record
Reishi · Lingzhi
Ganoderma lucidum
- Studies
- 1,830
- Avg relevance
- 60
- Latest
- 2026
Species record
Turkey Tail · Yun Zhi
Trametes versicolor
- Studies
- 1,828
- Avg relevance
- 41
- Latest
- 2026
Species record
Shiitake · Hua Gu
Lentinula edodes
- Studies
- 1,766
- Avg relevance
- 60
- Latest
- 2026
Species record
Cordyceps · Scarlet Club
Cordyceps militaris
- Studies
- 1,635
- Avg relevance
- 67
- Latest
- 2026
Species record
Cordyceps · Caterpillar Fungus
Ophiocordyceps sinensis
- Studies
- 1,576
- Avg relevance
- 59
- Latest
- 2026
Species record
Almond Mushroom · ABM
Agaricus blazei
- Studies
- 1,441
- Avg relevance
- 54
- Latest
- 2026
Species record
Enoki · Winter Mushroom
Flammulina velutipes
- Studies
- 1,403
- Avg relevance
- 47
- Latest
- 2026
Species record
King Oyster · Eryngii
Pleurotus eryngii
- Studies
- 1,278
- Avg relevance
- 60
- Latest
- 2026
Species record
Maitake · Hen of the Woods
Grifola frondosa
- Studies
- 1,276
- Avg relevance
- 48
- Latest
- 2026
Species record
Snow Fungus · Silver Ear
Tremella fuciformis
- Studies
- 1,052
- Avg relevance
- 29
- Latest
- 2026
Species record
Lion's Mane · Yamabushitake
Hericium erinaceus
- Studies
- 862
- Avg relevance
- 67
- Latest
- 2026
Species record
Chaga
Inonotus obliquus
- Studies
- 738
- Avg relevance
- 65
- Latest
- 2026
Species record
Mesima · Sanghwang
Phellinus linteus
- Studies
- 722
- Avg relevance
- 58
- Latest
- 2026
Species record
Niu-Chang-Chih
Antrodia camphorata
- Studies
- 496
- Avg relevance
- 63
- Latest
- 2026
Species record
Nameko · Nametake
Pholiota microspora
- Studies
- 421
- Avg relevance
- 29
- Latest
- 2026
Species record
Yellow Morel
Morchella esculenta
- Studies
- 392
- Avg relevance
- 42
- Latest
- 2026
Species record
Zhu Ling · Umbrella Polypore
Polyporus umbellatus
- Studies
- 263
- Avg relevance
- 55
- Latest
- 2026
Species record
Wood Ear · Kikurage
Auricularia auricula-judae
- Studies
- 254
- Avg relevance
- 51
- Latest
- 2026
Species record
Agarikon · Quinine Conk
Fomitopsis officinalis
- Studies
- 47
- Avg relevance
- 55
- Latest
- 2026
Articles
1,643 results
Showing 551–600 of 1,643
Niu-Chang-Chih · 2008 · Patent · journal metadata
LIVER PROTECTION COMPOUNDS OF THE CYCLOHEXENONE TYPE FROM ANTRODIA CAMPHORATA
The present invention relates to a compound of Antrodia camphorata used for liver protection, in particular to an extract, 4-hydroxy-2,3-dimethoxy-6-methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone which is isolated from Antrodia camphorata..
Niu-Chang-Chih · 2008 · Patent · journal metadata
NOVEL COMPOUNDS FROM ANTRODIA CAMPHORATA
The present invention relates to a novel compound and use thereof, in particular to Antroquinonol B and Antroquinonol C isolated from Antrodia camphorata extracts which can effectively inhibit the growth of cancer cells..
Niu-Chang-Chih · 2008 · Patent · journal metadata
Novel cyclohexenone compounds from antrodia camphorata and application thereof
The present invention relates to a novel compound and its uses, which is an extract isolated and purified from Antrodia camphorata, in particular to 4-hydroxy-2,3-dimethoxy-6-methy-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone, and its use in tumor growth inhibition..
Niu-Chang-Chih · 2008 · Patent · journal metadata
NOVEL CYCLOHEXENONE COMPOUNDS FROM ANTRODIA CAMPHORATA AND APPLICATION THEREOF
NOVEL CYCLOHEXENONE COMPOUNDS FROM ANTRODIA CAMPHORATA AND APPLICATION THEREOF The present invention relates to a novel compound and its uses, which is an extract isolated and purified from Antrodia camphorata, in particular to 4- hydroxy-2,3-dimethoxy-6-methy-5(3,7,1 1-trimethyl-dodeca-2,6, 10-trienyl)-….
Niu-Chang-Chih · 2008 · Patent · journal metadata
NOVEL CYCLOHEXENONE COMPOUNDS FROM ANTRODIA CAMPHORATA AND APPLICATION THEREOF
The present invention relates to a novel compound and its uses, which is an extract isolated and purified from Antrodia camphorata, in particular to 4-hydroxy--2,3-dimethoxy-6-methy-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)- cyclohex-2-enone, and its use in tumor growth inhibition..
Niu-Chang-Chih · 2008 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology
The adjuvant effects of Antrodia Camphorata extracts combined with anti-tumor agents on multidrug resistant human hepatoma cells.
AIM OF THE STUDY: The objectives of this study were to investigate the adjuvant anti-tumor effects of Antrodia camphorate in human hepatoma cells (C3A and PLC/PRF/5) which are resistance to most anti-tumor agents, elucidate the possible regulation pathways, and measure the tumor growth and survival rate in….
King Oyster · 2007 · Patent · journal metadata
ENDO-BIOPOLYMERS PRODUCED FROM A SUBMERGED MYCELLIM CULTURE OF PLEUROTUS ERYNGII HAVING ANTITUMOR EFFECTS
Endo-biopolymers produced from submerged mycelium culture of Pleurotus eryngii are provided to inhibit proliferation of tumor cancer cells, increase activity of natural killer(NK) cells in the spleen and activity of glutathione S-transferase in the liver..
Enoki · 2007 · Patent · journal metadata
Injection containing flammulina velutipes
The invention discloses a drug composition for treating various diseases and having distinct anti-hepatoma effect and anti-hepatitis effect, in particular relates to a drug composition injection preparation with flammulina velutipes polysaccharide as active ingredient..
Mesima · 2007 · Patent · journal metadata
MAKGEOLLI WITH PHELLINUS LINTEUS AND METHOD FOR MANUFACTURING THEREOF
Unrefined rice wine(makgeolli) with Phellinus linteus and a method for manufacturing thereof are provided to confer health-improving effects such as activating function of internal organs including heart, liver, spleen, lung, kidney and stomach, and detoxification on the unrefined rice wine(makgeolli)..
King Oyster · 2007 · Patent · journal metadata
METHOD FOR MANUFACTURING OF PLEUROTUS ERYNGII CHIPS ADDITIVE NATURAL ANTHOCYANIN
A method of manufacturing mushroom snacks using Pleurotus eryngii, natural anthocyanin pigments having an excellent liver protection function and high antioxidant activity and salt is provided to obtain the snacks rich in nutrients and having medicinal value of Pleurotus eryngii and anthocyanin pigments as well as….
Niu-Chang-Chih · 2007 · Patent · journal metadata
NOVEL MIXTURE AND COMPOUNDS FROM MYCELIA OF ANTRODIA CAMPHORATA AND USE THEREOF
A novel mixture extracted from mycelia of Antrodia camphorata and compounds isolated therefrom are provided to reduce maximum blood pressure, increase high density lipoprotein, and have central cholinergic agonism, hepatoprotection, antiinflammation and anticancer activities..
Niu-Chang-Chih · 2006 · Patent · journal metadata
CULTIVATION METHOD AND APPLICATIONS FOR ANTRODIA CAMPHORATA
A method for cultivating Antrodia Camphorata is provided. First, Antrodia Camphorata is pre-incubated on a sloped surface culture medium.
Niu-Chang-Chih · 2006 · Patent · journal metadata
Liver cancer resistant Antrodia camphorata and preparation method thererof
The invention discloses an Antrodia camphorata capsule for resisting hepatic carcinoma, which comprises the following constituents (by weight portions): Antrodia camphorate mycelium fermentation extract 20-100, protein-free maize starch or medicinal starch gum 200-480..
Chaga · 2006 · Research Support, Non U.S. Gov'T · BioFactors (Oxford, England)
Reversal of the TPA-induced inhibition of gap junctional intercellular communication by Chaga mushroom (Inonotus obliquus) extracts: effects on MAP kinases.
Chaga mushroom (Inonotus obliquus) has continued to receive attention as a folk medicine with indications for the treatment of cancers and digestive diseases. The anticarcinogenic effect of Chaga mushroom extract was investigated using a model system of gap junctional intercellular communication (GJIC) in WB-F344….
Reishi · 1989 · Journal Article · Nippon Nōgeikagaku Kaishi
Triterpenoids from the Fungus Ganoderma lucidum (Reishi)
Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Nippon Nōgeikagaku Kaishi in 1989. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..
Reishi · 1988 · Journal Article · Agricultural and Biological Chemistry
Bitterness and Structure Relationship of the Triterpenoids from Ganoderma lucidum (Reishi)
Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Agricultural and Biological Chemistry in 1988. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..
Reishi · 1986 · Journal Article · Agricultural and Biological Chemistry
Ganoderiol A and B, New Triterpenoids from the Fungus Ganoderma lucidum (Reishi)
Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Agricultural and Biological Chemistry in 1986. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..
Reishi · 1985 · Journal Article · Agricultural and Biological Chemistry
New Bitter C27 and C30 Terpenoids from the Fungus Ganoderma lucidum (Reishi)
Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Agricultural and Biological Chemistry in 1985. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..
Reishi · 1984 · Journal Article · Agricultural and Biological Chemistry
New Bitter C27 and C30 Terpenoids from the Fungus Ganoderma lucidum (Reishi)
Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Agricultural and Biological Chemistry in 1984. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..
Reishi · 2019 · Review · Advances in experimental medicine and biology
Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Liver Injury.
Ganoderma lucidum (G. lucidum, Lingzhi) has a wide range of hepatoprotective effects.
Shiitake · 2019 · Journal Article · Journal of biotechnology
Promotion of the growth and plant biomass degrading enzymes production in solid-state cultures of Lentinula edodes expressing Vitreoscilla hemoglobin gene.
Vitreoscilla hemoglobin (VHb), encoded by the Vitreoscilla hemoglobin gene (vgb), is highly effective at binding oxygen and delivering it to both prokaryotes and eukaryotes under hypoxic conditions. In this study, we introduced the vgb gene into shiitake mushrooms, and the mycelia of the transformatants grew faster..
Maitake · 2002 · Review · Alternative medicine review: a journal of clinical therapeutic
Can maitake MD-fraction aid cancer patients?
Maitake mushroom (Grifola frondosa) MD-fraction containing beta-1,6 glucan with beta-1,3 branched chains has previously exhibited strong anticancer activity by increasing immune-competent cell activity.1,2 In this non-random case series, a combination of MD-fraction and whole maitake powder was investigated to….
Maitake · 2001 · Review · Alternative medicine review: a journal of clinical therapeutic
Maitake extracts and their therapeutic potential.
Maitake (Grifola frondosa) is the Japanese name for an edible fungus with a large fruiting body characterized by overlapping caps. It is a premier culinary as well as medicinal mushroom.
Maitake · 1996 · Randomized Controlled Trial · Alternative therapies in health and medicine
The effect of maitake mushrooms on liver and serum lipids.
OBJECTIVE: To determine the efficacy of maitake mushrooms in inhibiting the elevation of liver and serum lipids in rats. DESIGN: Sprague-Dawley rats with hyperlipidemia were used to measure and compare the values of cholesterol, phospholipids, and triglycerides between cholesterol-fed rats and rats whose diets were….
Reishi · 2024 · Published Erratum · Cancer cell international
Correction: Exploring the anti-cancer potential of Ganoderma Lucidum polysaccharides (GLPs) and their versatile role in enhancing drug delivery systems: a multifaceted approach to combat cancer.
Metadata-grounded summary: This published erratum indexes research on Ganoderma lucidum in Cancer cell international in 2024. MycoData maps the paper to oncology, immune support, liver support based on its title, species context, article metadata, and study classification..
Reishi · 2023 · Journal Article · Journal of primary health care
Ganoderma lucidum.
Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Journal of primary health care in 2023. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..
Maitake · 2023 · Preprint · journal metadata
Pharmacokinetic Parameters and Tissular Biodistribution of 1,3 β-glucans From Maitake Pro4x in Balbc Mice.
The objective of this study was to examine the pharmacokinetic parameters of 1,3-beta-glucans from Maitake Pro4X in BALBc mice through oral and intravenous (IV) administration..
Reishi · 2022 · Journal Article · Mushroom Science and Biotechnology
Identification, characterization and expression of a glutamic protease gene from Ganoderma lucidum
Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Mushroom Science and Biotechnology in 2022. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..
Snow Fungus · 2022 · Research Article · Current issues in molecular biology
Tremella fuciformis Crude Polysaccharides Attenuates Steatosis and Suppresses Inflammation in Diet-Induced NAFLD Mice.
Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disorder characterized by an enhanced accumulation of lipids, which affects around 40% of the world's population. The T..
Reishi · 2021 · Journal Article · Mushroom Science and Biotechnology
Cultivation of Ganoderma lucidum and G. sinense on medium containing bamboo chips
Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Mushroom Science and Biotechnology in 2021. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..
Almond Mushroom · 2018 · Evaluation Study · Food & function
A natural food ingredient based on ergosterol: optimization of the extraction from Agaricus blazei, evaluation of bioactive properties and incorporation in yogurts.
In recent years, mycosterols have emerged as potential functional ingredients for the development of sterol-enriched food products and dietary supplements. Agaricus blazei is a mushroom rich in bioactive compounds.
Turkey Tail · 2018 · Research Support, Non U.S. Gov'T · PloS one
Potential activities and mechanisms of extracellular polysaccharopeptides from fermented Trametes versicolor on regulating glucose homeostasis in insulin-resistant HepG2 cells.
Polysaccharides derived from mushrooms have potential to control blood sugar, reduce insulin resistance and prevent diabetic complications. The intracellular polysaccharopeptides of Trametes versicolor (TV) have been used as immunologic and oncologic adjuvants..
Lion's Mane · 2017 · Research Support, Non U.S. Gov'T · Scientific reports
Antihyperglycaemic and organic protective effects on pancreas, liver and kidney by polysaccharides from Hericium erinaceus SG-02 in streptozotocin-induced diabetic mice.
The present work was designed to investigate the antihyperglycaemic and protective effects of two Hericium erinaceus intracellular polysaccharide (HIPS) purified fractions (HIPS1 and HIPS2) from mycelia of H. erinaceus SG-02 on pancreas, liver and kidney in streptozotocin (STZ)-induced diabetic mice..
Mesima · 2016 · Letter · International journal of molecular sciences
Ionone Derivatives from the Mycelium of Phellinus linteus and the Inhibitory Effect on Activated Rat Hepatic Stellate Cells.
Three new γ-ionylideneacetic acid derivatives, phellinulins A-C (1-3), were characterized from the mycelium extract of Phellinus linteus. The chemical structures were established based on the spectroscopic analysis..
Shiitake · 2016 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry
Water-Soluble Compounds from Lentinula edodes Influencing the HMG-CoA Reductase Activity and the Expression of Genes Involved in the Cholesterol Metabolism.
A water extract from Lentinula edodes (LWE) showed HMG-CoA reductase inhibitory activity but contained no statins. NMR indicated the presence of water-soluble α- and β-glucans and fucomannogalactans..
Shiitake · 2015 · Journal Article · Biochemical and biophysical research communications
Anti-HCV effect of Lentinula edodes mycelia solid culture extracts and low-molecular-weight lignin.
Lentinula edodes mycelia solid culture extract (MSCE) contains several bioactive molecules, including some polyphenolic compounds, which exert immunomodulatory, antitumor, and hepatoprotective effects..
Niu-Chang-Chih · 2015 · Research Article · Evidence-based complementary and alternative medicine: eCAM
Antrodia camphorata Potentiates Neuroprotection against Cerebral Ischemia in Rats via Downregulation of iNOS/HO-1/Bax and Activated Caspase-3 and Inhibition of Hydroxyl Radical Formation.
Antrodia camphorata (A. camphorata) is a fungus generally used in Chinese folk medicine for treatment of viral hepatitis and cancer.
Snow Fungus · 2015 · Journal Article · Biotechnology letters
Oral vaccination of mice with Tremella fuciformis yeast-like conidium cells expressing HBsAg
Tremella fuciformis yeast-like conidium (YLC) cells were transformed by co-cultivation with Agrobacterium cells harboring the hepatitis B surface antigen (HBsAg) gene construct under the control of the CaMV35S promoter. Integration of HBsAg DNA into the YLC genome was confirmed by PCR and dot-blot hybridization..
Mesima · 2015 · Research Article · Journal of clinical medicine research
Potent Anticancer Effects of Bioactive Mushroom Extracts (Phellinus linteus) on a Variety of Human Cancer Cells.
BACKGROUND: Although several therapeutic options are currently available for patients with various cancers, the outcomes are often disappointing and a more effective modality needs to be promptly established..
Lion's Mane · 2015 · Research Article · Evidence-based complementary and alternative medicine: eCAM
Protective Effect of Hericium erinaceus on Alcohol Induced Hepatotoxicity in Mice.
We investigated the effects of Hericium erinaceus (HEM) on liver injury induced by acute alcohol administration in mice. Mice received ethanol (5 g/kg BW) by gavage every 12 hrs for a total of 3 doses.
Chaga · 2014 · Research Article · Evidence-based complementary and alternative medicine: eCAM
Protective Effect of Polysaccharides from Inonotus obliquus on Streptozotocin-Induced Diabetic Symptoms and Their Potential Mechanisms in Rats.
The present study aimed to evaluate the therapeutic effects of polysaccharides from Inonotus obliquus (PIO) on streptozotocin- (STZ-) induced diabetic symptoms and their potential mechanisms..
Chaga · 2013 · Research Article · Molecules (Basel, Switzerland)
Anti-oxidant and anti-inflammatory activities of Inonotus obliquus and germinated brown rice extracts.
Inonotus obliquus (IO) is parasitic mushroom that grows on birch and other trees in Russia, Korea, Europe and United States. However, IO is not readily available for consumption due to its high cost and difficult growth..
Yellow Morel · 2013 · Journal Article · Experimental and toxicologic pathology: official journal of the Gesellschaft fur Toxikologische Pathologie
Hepatoprotective activity of cultured mycelium of Morel mushroom, Morchella esculenta.
The hepatoprotective activity of cultured mycelium of morel mushroom Morchella esculenta against CCl(4) and ethanol induced chronic hepatotoxicity was investigated..
Yellow Morel · 2013 · Journal Article · Biotechnology letters
Induction of apoptosis in HepG2 cells by polysaccharide MEP-II from the fermentation broth of Morchella esculenta
A novel polysaccharide, MEP-II, isolated from the fermentation broth of Morchella esculenta inhibited the proliferation of human hepatoma cell line (HepG2) through an apoptotic pathway..
Niu-Chang-Chih · 2012 · Journal Article · Food chemistry
Protective effect of antrosterol from Antrodia camphorata submerged whole broth against carbon tetrachloride-induced acute liver injury in mice
The hepatoprotective potential of antrosterol (ergostatrien-3β-ol, ST1) from Antrodia camphorata (AC) against carbon tetrachloride (CClâ)-induced liver damage was evaluated in preventive models in mice..
Mesima · 2012 · Research Article · Chinese medicine
Protective effect of Phellinus linteus polysaccharide extracts against thioacetamide-induced liver fibrosis in rats: a proteomics analysis.
BACKGROUND: The hepatoprotective potential of Phellinus linteus polysaccharide (PLP) extracts has been described. However, the molecular mechanism of PLP for the inhibition of liver fibrosis is unclear..
Niu-Chang-Chih · 2012 · Research Article · Evidence-based complementary and alternative medicine: eCAM
Triterpenoid-Rich Extract from Antrodia camphorata Improves Physical Fatigue and Exercise Performance in Mice.
Antrodia camphorata (AC) is an endemic mushroom that grows in Taiwan. We investigated the fatigue-alleviating effects of AC on endurance capacity in swim-exercised and weight-loading mice..
Chaga · 2011 · Journal Article · Bulletin of experimental biology and medicine
Antiviral activity of Inonotus obliquus fungus extract towards infection caused by hepatitis C virus in cell cultures.
Fractions of Inonotus obliquus fungus water extract exhibited a virucidal effect towards hepatitis C virus: it 100-fold reduced its infective properties within 10 min..
Mesima · 2011 · Journal Article · Journal of ethnopharmacology
Orally administered mycelial culture of Phellinus linteus exhibits antitumor effects in hepatoma cell-bearing mice.
AIM OF THE STUDY: The aim of this study was to evaluate the anticancer effect of a mycelial culture from Phellinus linteus PL-7 (MCPL-7) and to elucidate its potential mechanism in vivo. MATERIALS AND METHODS: SCID CB-17 mice received a transplant of Hep3B cells followed by daily MCPL-7 administrations for 8 weeks..
Lion's Mane · 2010 · Journal Article · Cancer letters
Hericium erinaceus enhances doxorubicin-induced apoptosis in human hepatocellular carcinoma cells.
It has been demonstrated that the Hericium erinaceus (HE) mushroom, which primarily consists of polysaccharides, possesses anti-tumor activities. However, the mechanisms by which HE inhibits human hepatocellular carcinoma growth remain unknown..