MycoData

UNLABELLED: Lentinula edodes has the potential to degrade woody and nonwoody lignocellulosic biomass. However, the mechanism of lignocellulose degradation by L.

Immune supportMetabolic health

High relevance

Niu-Chang-Chih · 2017 · Comparative Study · Proteomics

Comparative Transcriptomic and Proteomic Analyses Reveal a FluG-Mediated Signaling Pathway Relating to Asexual Sporulation of Antrodia camphorata.

Medicinal mushroom Antrodia camphorata sporulate large numbers of arthroconidia in submerged fermentation, which is rarely reported in basidiomycetous fungi. Nevertheless, the molecular mechanisms underlying this asexual sporulation (conidiation) remain unclear..

High relevance

Lion's Mane · 2017 · Other · Data in brief

Dataset on records of Hericium erinaceus in Slovakia.

The data presented in this article are related to the research article entitled "Habitat preferences of Hericium erinaceus in Slovakia" (Kunca and Čiliak, 2016) [FUNECO607] [2]. The dataset include all available and unpublished data from Slovakia, besides the records from the same tree or stem..

High relevance

Enoki · 2017 · Comparative Study · Current microbiology

iTRAQ-Based Comparative Proteomics Analysis of the Fruiting Dikaryon and the Non-fruiting Monokaryon of Flammulina velutipes.

Flammulina velutipes is a potentially excellent fungus to study basic mechanisms of basidiomycete mycelium biology. To provide a better understanding of the mechanism of hyphae growth and fruit-body formation, the biological functions of the differentially abundant proteins between the fruiting dikaryon and the….

Metabolic health

High relevance

Shiitake · 2017 · Other · Data in brief

Long-read transcriptome data for improved gene prediction in Lentinula edodes.

Lentinula edodes is one of the most popular edible mushrooms in the world and contains useful medicinal components such as lentinan. The whole-genome sequence of L..

High relevance

Turkey Tail · 2017 · Research Support, Non U.S. Gov'T · Scientific reports

Metabolomic differential analysis of interspecific interactions among white rot fungi Trametes versicolor, Dichomitus squalens and Pleurotus ostreatus.

Interspecific fungal antagonism occurred commonly in the interaction zone of different white rot fungi. This competitive interaction could markedly influence the metabolic pathway of intracellular metabolites, which was associated with the fungal morphology change and growth restriction..

Metabolic health

High relevance

Zhu Ling · 2017 · Research Support, Non U.S. Gov'T · Scientific reports

Phylogenetic constrains on Polyporus umbellatus-Armillaria associations.

It has been well established that some Armillaria species are symbionts of Polyporus umbellatus, However, little is known about the evolutionary history of P. umbellatus-Armillaria associations.

High relevance

Turkey Tail · 2017 · Research Support, Non U.S. Gov'T · Scientific reports

Proteomic analysis reveals large amounts of decomposition enzymes and major metabolic pathways involved in algicidal process of Trametes versicolor F21a.

A recent algicidal mode indicates that fungal mycelia can wrap and eliminate almost all co-cultivated algal cells within a short time span. However, the underlying molecular mechanism is rarely understood..

Immune supportEnergy & fatigueMetabolic health

High relevance

Zhu Ling · 2017 · Research Support, Non U.S. Gov'T · Scientific reports

SWATH label-free proteomics analyses revealed the roles of oxidative stress and antioxidant defensing system in sclerotia formation of Polyporus umbellatus.

Understanding the initiation and maturing mechanisms is important for rational manipulating sclerotia differentiation and growth from hypha of Polyporus umbellatus. Proteomes in P.

Respiratory

High relevance

Oyster Mushroom · 2017 · Journal Article · Applied microbiology and biotechnology

Valorization of spent oyster mushroom substrate and laccase recovery through successive solid state cultivation of Pleurotus, Ganoderma, and Lentinula strains.

Spent mushroom substrate (SMS) of Pleurotus ostreatus was supplemented with wheat bran and soybean flour in various proportions to obtain C/N ratios of 10, 20, and 30, and their effect was evaluated in successive cultivation of Pleurotus ostreatus, Pleurotus pulmonarius, Ganoderma adspersum, Ganoderma resinaceum, and….

Immune supportGut & microbiome

High relevance

Niu-Chang-Chih · 2016 · Research Support, Non U.S. Gov'T · International immunopharmacology

4,7-Dimethoxy-5-methyl-1,3-benzodioxole from Antrodia camphorata inhibits LPS-induced inflammation via suppression of NF-κB and induction HO-1 in RAW264.7 cells.

Several benzenoid compounds have been isolated from Antrodia camphorata are known to have excellent anti-inflammatory activity. In this study, we investigated the anti-inflammatory potential of 4,7-dimethoxy-5-methyl-1,3-benzodioxole (DMB), one of the major benzenoid compounds isolated from the mycelia of A..

OncologyImmune supportEnergy & fatigue

High relevance

Lion's Mane · 2016 · Research Support, Non U.S. Gov'T · Journal of ethnopharmacology

Anti-Helicobacter pylori activity of bioactive components isolated from Hericium erinaceus.

ETHNOPHARMACOLOGICAL RELEVANCE: The fungus Hericium erinaceus (Bull.) Pers is used in Chinese traditional medicine to treat symptoms related to gastric ulcers. Different extracts from the fungus were assessed for anti-Helicobacter pylori activity to investigate the antibacterial activity of the ethanol extracts from….

Oncology

High relevance

Maitake · 2016 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Anti-tumor and immunomodulatory activity of selenium (Se)-polysaccharide from Se-enriched Grifola frondosa.

A polysaccharide termed Se-GP11 was extracted and purified from Se-enriched Grifola frondosa in our previous study. This study investigated the characterization, anti-tumor and immunomodulatory activity of Se-GP11..

OncologyImmune supportMetabolic health

High relevance

Enoki · 2016 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Antioxidative and renoprotective effects of residue polysaccharides from Flammulina velutipes.

Three extractable polysaccharides including Ac-RPS, Al-RPS and En-RPS were extracted from the residue of Flammulina velutipes and their antioxidative and renoprotective effects on STZ-induced mice were investigated..

Immune supportMetabolic health

High relevance

Enoki · 2016 · Research Support, Non U.S. Gov'T · The Journal of organic chemistry

Bioactive Sesquiterpenes from the Edible Mushroom Flammulina velutipes and Their Biosynthetic Pathway Confirmed by Genome Analysis and Chemical Evidence.

Twelve putative sesquiterpene synthases genes were found in clades along with enzymes with 1,6-, 1,10-, and 1,11-cyclase activities in the genome of Flammulina velutipes. Chemistry investigation of F..

High relevance

Mesima · 2016 · Comparative Study · Journal of food and drug analysis

Comparing the functional components, SOD-like activities, antimutagenicity, and nutrient compositions of Phellinus igniarius and Phellinus linteus mushrooms.

Many species of the genus Phellinus possess beneficial properties, including antioxidant, immune-enhancing, and antimutagenic effects. Phenolic compounds and polysaccharides are two kinds of bioactive compounds; however, few studies have compared the differences between Phellinus igniarius and Phellinus linteus in….

Immune support

High relevance

Snow Fungus · 2016 · Research Support, Non U.S. Gov'T · Journal of microbiology (Seoul, Korea)

Comparing the sugar profiles and primary structures of alkali-extracted water-soluble polysaccharides in cell wall between the yeast and mycelial phases from Tremella fuciformis.

To gain insights into dimorphism, cell wall polysaccharides from Tremella fuciformis strains were obtained from alkali-extracted water-soluble fractions PTF-M38 (from the mycelial form), PTF-Y3 and PTF-Y8 (from the yeast form) of T. fuciformis strains were used to gain some insights into dimorphism study..

Immune supportMetabolic health

High relevance

Turkey Tail · 2016 · Research Support, Non U.S. Gov'T · Scientific reports

Discovery of novel xylosides in co-culture of basidiomycetes Trametes versicolor and Ganoderma applanatum by integrated metabolomics and bioinformatics.

Transcriptomic analysis of cultured fungi suggests that many genes for secondary metabolite synthesis are presumably silent under standard laboratory condition. In order to investigate the expression of silent genes in symbiotic systems, 136 fungi-fungi symbiotic systems were built up by co-culturing seventeen….

Respiratory

High relevance

Enoki · 2016 · Brief Report · Genome announcements

Draft Genome Sequence of the Basidiomycetous Fungus Flammulina velutipes TR19.

Here, we report the draft genome sequence of Flammulina velutipes TR19, which was newly isolated from commercial strains in Japan. The genes related to fruiting body formation in the basidiomycete were identified by whole-genome analysis..

High relevance

Almond Mushroom · 2016 · Research Support, Non U.S. Gov'T · PloS one

Effect of a Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSan™, on Symptoms, Fatigue and Quality of Life in Patients with Ulcerative Colitis in a Randomized Single-Blinded Placebo Controlled Study.

BACKGROUND: Ingestion of AndoSan™, based on the mushroom Agaricus blazei Murill, has previously been shown to exhibit anti-inflammatory effects because of reduction of pro-inflammatory cytokines in healthy individuals and patients with ulcerative colitis..

Immune supportEnergy & fatigueGut & microbiome

High relevance

Enoki · 2016 · Research Support, Non U.S. Gov'T · Food chemistry

Effect of hot air drying on volatile compounds of Flammulina velutipes detected by HS-SPME-GC-MS and electronic nose.

Volatile compounds are important factors that affect the flavor quality of Flammulina velutipes, but the changes occurring during hot air drying is still unclear. To clarify the dynamic changes of flavor components during hot air drying, comprehensive flavor characterization and volatile compounds of F..

High relevance

Mesima · 2016 · Research Support, Non U.S. Gov'T · Applied biochemistry and biotechnology

Endogenous and Exogenous Calcium Involved in the Betulin Production from Submerged Culture of Phellinus linteus Induced by Hydrogen Sulfide.

Using pharmacological and biochemical approaches, Ca(2+) involved in the betulin production in mycelia of Phellinus linteus induced by hydrogen sulfide (H2S) were investigated..

High relevance

Lion's Mane · 2016 · Research Support, Non U.S. Gov'T · Journal of natural products

Erinacine S, a Rare Sesterterpene from the Mycelia of Hericium erinaceus.

A new sesterterpene, erinacine S, and one cyathane diterpene xyloside, erinacine A, were isolated from the ethanol extract of the mycelia of Hericium erinaceus. Their structures were elucidated by spectroscopic and X-ray analysis..

Cognition & nervesMetabolic health

High relevance

Maitake · 2016 · Research Support, Non U.S. Gov'T · Natural product research

Extraction, identification and antimicrobial activity of a new furanone, grifolaone A, from Grifola frondosa.

A furanone (1), (S)-methyl 2-(2-hydroxy-3,4-dimethyl-5-oxo-2,5-dihydrofuran-2-yl)acetate, was isolated from the edible mushroom Grifola frondosa. Mass spectrometry and NMR analyses were used to elucidate the structure of this compound, and its absolute configuration was determined using circular dichroism….

High relevance

Maitake · 2016 · Research Support, Non U.S. Gov'T · Nutrition and cancer

Grifola frondosa Glycoprotein GFG-3a Arrests S phase, Alters Proteome, and Induces Apoptosis in Human Gastric Cancer Cells.

GFG-3a is a novel glycoprotein previously purified from the fermented mycelia of Grifola frondosa with novel sugar compositions and protein sequencing. The present study aims to investigate its effects on the cell cycle, differential proteins expression, and apoptosis of human gastric cancer SGC-7901 cells..

OncologyEnergy & fatigue

High relevance

Lion's Mane · 2016 · Research Support, Non U.S. Gov'T · Oxidative medicine and cellular longevity

Hericium erinaceus Inhibits TNF-α-Induced Angiogenesis and ROS Generation through Suppression of MMP-9/NF-κB Signaling and Activation of Nrf2-Mediated Antioxidant Genes in Human EA.hy926 Endothelial Cells.

Hericium erinaceus (HE) is an edible mushroom that has been shown to exhibit anticancer and anti-inflammatory activities. We investigated the antiangiogenic and antioxidant potentials of ethanol extracts of HE in human endothelial (EA.hy926) cells upon tumor necrosis factor-α- (TNF-α-) stimulation (10 ng/mL)..

OncologyImmune supportEnergy & fatigue

High relevance

Lion's Mane · 2016 · Retracted Publication · Journal of translational medicine

Hericium erinaceus mycelium and its isolated erinacine A protection from MPTP-induced neurotoxicity through the ER stress, triggering an apoptosis cascade.

BACKGROUND: Hericium erinaceus is an edible mushroom; its various pharmacological effects which have been investigated. This study aimed to demonstrate whether efficacy of oral administration of H..

OncologyImmune supportCognition & nerves

High relevance

Enoki · 2016 · Research Support, Non U.S. Gov'T · Food chemistry

Identification of flavonoids from Flammulina velutipes and its neuroprotective effect on pheochromocytoma-12 cells.

The flavonoids from Flammulina velutipes (FVF) were isolated and the chemical composition of FVF was identified by high-performance liquid chromatography/mass spectrometry (HPLC/MS)..

OncologyCognition & nervesEnergy & fatigue

High relevance

Shiitake · 2016 · Clinical Study · Alternative therapies in health and medicine

Improvement of QOL and Immunological Function With Lentinula Edodes Mycelia in Patients Undergoing Cancer Immunotherapy: An Open Pilot Study.

Context • Combined treatment with an extract of Lentinula edodes mycelia (LEM) and chemotherapy has been reported to improve quality of life (QOL) and immunological function in cancer patients. However, those effects have not been elucidated for patients receiving cancer immunotherapy..

OncologyImmune support

High relevance

Zhu Ling · 2016 · Research Support, Non U.S. Gov'T · Molecular medicine reports

Induction of apoptosis in MCF‑7 human breast cancer cells by Khz (fusion of Ganoderma lucidum and Polyporus umbellatus mycelium).

Khz (fusion of Ganoderma lucidum and Polyporus umbellatus), isolated from the mycelia of G. lucidum and P.

OncologyEnergy & fatigue

High relevance

Chaga · 2016 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Investigation of three lignin complexes with antioxidant and immunological capacities from Inonotus obliquus.

Mushroom Inonotus obliquus (I. obliquus), a folk medicine, has been widely used to treat several human malicious tumors since 16th century.

OncologyImmune support

High relevance

Mesima · 2016 · Letter · International journal of molecular sciences

Ionone Derivatives from the Mycelium of Phellinus linteus and the Inhibitory Effect on Activated Rat Hepatic Stellate Cells.

Three new γ-ionylideneacetic acid derivatives, phellinulins A-C (1-3), were characterized from the mycelium extract of Phellinus linteus. The chemical structures were established based on the spectroscopic analysis..

Liver support

High relevance

Mesima · 2016 · Research Support, Non U.S. Gov'T · Journal of bioscience and bioengineering

Modulation of T cell response by Phellinus linteus.

Phellinus linteus, a species of mushroom, has been shown to contribute to health benefits, such as anti-inflammatory activity and immunomodulatory efficacy. The aim of this study was to analyze the most effective constituents of P..

Immune support

High relevance

Enoki · 2016 · Research Support, Non U.S. Gov'T · FEMS microbiology letters

Mushroom tumor: a new disease on Flammulina velutipes caused by Ochrobactrum pseudogrignonense.

Mushroom tumor on Flammulina velutipes has become the main disease during the off-season cultivation of F. velutipes while the causal organism has remained unknown..

Oncology

High relevance

Mesima · 2016 · Research Support, Non U.S. Gov'T · Nutrition research (New York, N.Y.)

Neuroprotective effects of the Phellinus linteus ethyl acetate extract against H2O2-induced apoptotic cell death of SK-N-MC cells.

Numerous studies have suggested that neuronal cells are protected against oxidative stress-induced cell damage by antioxidants, such as polyphenolic compounds. Phellinus linteus (PL) has traditionally been used to treat various symptoms in East Asian countries..

OncologyCognition & nervesEnergy & fatigue

High relevance

Shiitake · 2016 · Brief Report · Mycobiology

Oxalic Acid from Lentinula edodes Culture Filtrate: Antimicrobial Activity on Phytopathogenic Bacteria and Qualitative and Quantitative Analyses.

The culture filtrate of Lentinula edodes shows potent antimicrobial activity against the plant pathogenic bacteria Ralstonia solanacearum. Bioassay-guided fractionation was conducted using Diaion HP-20 column chromatography, and the insoluble active compound was not adsorbed on the resin..

Energy & fatigue

High relevance

Enoki · 2016 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Purification, characterization and antioxidant activity of polysaccharides from Flammulina velutipes residue.

In this study, we isolated polysaccharides from Flammulina velutipes residue (FVRP) using microwave-assisted extraction and then purified the polysaccharides by column chromatography to yield FVRP-1, FVRP-2 and FVRP-3..

Immune supportMetabolic health

High relevance

Chaga · 2016 · Research Support, Non U.S. Gov'T · Scientific reports

Regulation of Anticancer Styrylpyrone Biosynthesis in the Medicinal Mushroom Inonotus obliquus Requires Thioredoxin Mediated Transnitrosylation of S-nitrosoglutathione Reductase.

The medicinal macrofungus Inonotus obliquus widely utilized as folk medicine in Russia and Baltic countries is a source of phenylpropanoid-derived styrylpyrone polyphenols that can inhibit tumor proliferation. Insights into the regulatory machinery that controls I..

Oncology

High relevance

Mesima · 2016 · Research Support, Non U.S. Gov'T · Journal of microbiology (Seoul, Korea)

Species identity of Phellinus linteus (sanghuang) extensively used as a medicinal mushroom in Korea.

Sanghuang is a medicinal mushroom that has gained particular attention in Korea. It has been extensively studied for the past few decades as a natural immune booster and cancer suppressor..

OncologyImmune support

High relevance

Turkey Tail · 2016 · Research Support, Non U.S. Gov'T · Water environment research: a research publication of the Water Environment Federation

Statistical Correlation between Ligninolytic Enzymes Secretion and Remazol Brilliant Yellow-3GL Dye Degradation Potential of Trametes versicolor IBL-04.

Trametes versicolor IBL-04 was used for biodegradation of Remazol Brilliant Yellow 3-GL (RBY3-GL) reactive textile dye in Kirk's basal salts medium. During the initial screening study, the maximum decolorization (93.5%) of RBY3-GL was achieved in 7 days' shaking incubation period at pH 4 and 30 °C..

High relevance

Maitake · 2016 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Structural characterization and antiviral activity of a novel heteropolysaccharide isolated from Grifola frondosa against enterovirus 71.

A novel heteropolysaccharide from Grifola frondosa mycelia was extracted and purified using DEAE Sephadex A-50 and Sephadex G-200 chromatography. Fourier transform infrared (FT-IR) spectroscopy and nuclear magnetic resonance ((1)H NMR and (13)C NMR) spectroscopy were used to decipher the structure of the purified G..

Immune supportRespiratory

High relevance

Zhu Ling · 2016 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Structure elucidation and antioxidant activity of a novel polysaccharide from Polyporus umbellatus sclerotia.

A novel water-soluble polysaccharide PUP60S2, with a molecular weight of 1.44×10(4)Da, was obtained from the sclerotia of Polyporus umbellatus by hot water extraction, ethanol precipitation, anion-exchange and size-exclusion chromatography. PUP60S2 was a polysaccharide comprised of about 22.3% glucuronic acid..

Immune supportMetabolic health

High relevance

Lion's Mane · 2016 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Structure elucidation of a bioactive polysaccharide from fruiting bodies of Hericium erinaceus in different maturation stages.

HPB-3, a heteropolysaccharide, with a mean molecular weight of 1.5×10(4)Da, was obtained from the maturating-stage IV, V and VI fruiting body of Hericium erinaceus, exhibited higher macrophages stimulation activities, was able to upregulate the functional events mediated by activated macrophages, such as production of….

Immune supportMetabolic health

High relevance

Snow Fungus · 2016 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Structure, physical property and antioxidant activity of catechin grafted Tremella fuciformis polysaccharide.

In this study, structural characterization, physical property and antioxidant activity of catechin grafted Tremella fuciformis polysaccharide (catechin-g-TPS) were investigated. Crude polysaccharides were isolated from the fruit bodies of T..

Immune support

High relevance

Mesima · 2016 · Research Support, Non U.S. Gov'T · Ultrasonics sonochemistry

Ultrasonic effects on the degradation kinetics, preliminary characterization and antioxidant activities of polysaccharides from Phellinus linteus mycelia.

In this study, a high-molecular-weight polysaccharide PL-N isolated from the alkaline extract of Phellinus linteus mycelia was degraded by ultrasound. Results showed that ultrasound treatment at different ultrasonic intensities decreased the intrinsic viscosity and molecular weight of PL-N, as well as narrowed the….

Immune support

High relevance

Shiitake · 2016 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Water-Soluble Compounds from Lentinula edodes Influencing the HMG-CoA Reductase Activity and the Expression of Genes Involved in the Cholesterol Metabolism.

A water extract from Lentinula edodes (LWE) showed HMG-CoA reductase inhibitory activity but contained no statins. NMR indicated the presence of water-soluble α- and β-glucans and fucomannogalactans..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Zhu Ling · 2015 · Journal Article · Yao xue xue bao = Acta pharmaceutica Sinica

[Molecular cloning and characterization of four small GTPase genes from medicinal fungus Polyporus umbellatus].

Four small GTPase genes which may be relative to sclerotial development were firstly cloned from medicinal fungus Polyporus umbellatus using rapid amplification of cDNA end PCR (RACE) method..

High relevance

Turkey Tail · 2015 · Journal Article · Forest Pathology

A histological investigation of Oriental beech wood decayed by Pleurotus ostreatus and Trametes versicolor

Chemical, light and electron microscopic studies were carried out on wood of Oriental beech (Fagus orientalis Lipsky) decayed by the white‐rot fungi Pleurotus ostreatus and Trametes versicolor for 30, 60 and 120 days according to the modified European standard EN 113..

High relevance

Shiitake · 2015 · Journal Article · Scientific reports

A novel cysteine desulfurase influencing organosulfur compounds in Lentinula edodes.

Organosulfur compounds are the basis for the unique aroma of Lentinula edodes, and cysteine sulfoxide lyase (C-S lyase) is the key enzyme in this trait. The enzyme from Alliium sativum has been crystallized and well-characterized; however, there have been no reports of the characterization of fungi C-S lyase at the….

High relevance

Maitake · 2015 · Journal Article · Mycoscience

A putative transcription factor Gf.BMR1 in Grifola frondosa, the homolog of BMR1 in Bipolaris oryzae, was strongly induced by near-ultraviolet light and blue light

Near-ultraviolet (NUV) light and blue light have different effects on fungal fruiting body development. However, while blue light signaling has been well studied, the process of NUV-induced signals transduction remains unclear..

Skin & hydration