MycoData

In this study, we assessed the degradation of the sulfonamides sulfapyridine (SPY) and sulfathiazole (STZ) by the white-rot fungus Trametes versicolor. Complete degradation was accomplished in fungal cultures at initial pollutant concentrations of approximately 10 mg L(-1), although a longer period of time was needed….

Energy & fatigue

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering

Dechlorination of chlorinated compounds by Trametes versicolor ATCC 200801 crude laccase and quantitative structure-activity relationship of toxicity.

Chlorinated compounds constitute an important class of xenobiotics. Crude laccase was produced using Trametes versicolor ATCC (200801) in potato dextrose broth, with wheat bran as an inducing medium, and its ability to dechlorinate eight compounds was determined..

Energy & fatigue

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Water research

Degradation of carbamazepine by Trametes versicolor in an air pulsed fluidized bed bioreactor and identification of intermediates.

The paper describes the aerobic degradation of carbamazepine (CBZ), an anti-epileptic drug widely found in aquatic environment, from Erlenmeyer flask to bioreactor by the white-rot fungus Trametes versicolor..

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Journal of environmental management

Degradation of UV filters in sewage sludge and 4-MBC in liquid medium by the ligninolytic fungus Trametes versicolor.

Ultraviolet (UV) filters are xenobiotic compounds that can enter the environment through the liquid effluent of wastewater treatment plants (WWTPs) and through adsorption in the sludge by-product because of their high hydrophobicity, as the sludge is subsequently applied as a fertiliser..

Skin & hydration

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Journal of bioscience and bioengineering

Determination of co-metabolism for 1,1,1-trichloro-2,2-bis(4-chlorophenyl) ethane (DDT) degradation with enzymes from Trametes versicolor U97.

Trametes versicolor U97 isolated from nature degraded 73% of the 1,1,1-trichloro-2,2-bis(4-chlorophenyl) ethane (DDT) in a malt extract liquid medium after a 40-d incubation period. This paper presents a kinetic study of microbial growth using the Monod equation.

Metabolic health

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Applied biochemistry and biotechnology

Effect of the inducers veratryl alcohol, Xylidine, and ligninosulphonates on activity and thermal stability and inactivation kinetics of laccase from Trametes versicolor.

Laccase production from Trametes versicolor was improved in the presence of the inducers ligninosulphonates, veratryl alcohol, and xylidine respectively two-, four-, and eightfold..

Medium relevance

Enoki · 2012 · Research Support, Non U.S. Gov'T · Animal science journal = Nihon chikusan Gakkaiho

Effects of fermented mushroom (Flammulina velutipes) by-product diets on growth performance and carcass traits in growing-fattening Berkshire pigs.

This study was conducted to investigate effects of fermented mushroom (Flammulina velutipes) by-product diets on the growth performance and carcass traits in growing-fattening Berkshire pigs..

Energy & fatigueMetabolic healthGut & microbiome

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Bioresource technology

Engineering and production of laccase from Trametes versicolor in the yeast Yarrowia lipolytica.

The lcc1 gene coding for the laccase from Trametes versicolor DSM11269 was cloned into the genome of Yarrowia lipolytica using either single or multiple integration sites..

Medium relevance

Enoki · 2012 · Research Support, Non U.S. Gov'T · International journal of nanomedicine

Enhanced oral bioavailability of a sterol-loaded microemulsion formulation of Flammulina velutipes, a potential antitumor drug.

PURPOSE: To investigate the growth inhibition activity of Flammulina velutipes sterol (FVS) against certain human cancer cell lines (gastric SGC and colon LoVo) and to evaluate the optimum microemulsion prescription, as well as the pharmacokinetics of encapsulated FVS..

OncologyMetabolic healthGut & microbiome

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Journal of environmental sciences (China)

Enhanced oxidation of benzo[a]pyrene by crude enzyme extracts produced during interspecific fungal interaction of Trametes versicolor and Phanerochaete chrysosporium.

The effects of interspecific fungal interactions between Trametes versicolor and Phanerochaete chrysosporium on laccase activity and enzymatic oxidation of polycyclic aromatic hydrocarbons (PAHs) were investigated..

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Flocculation and haze removal from crude beer using in-house produced laccase from Trametes versicolor cultured on brewer's spent grain.

The potential of brewer's spent grain (BSG), a common waste from the brewing industry, as a support-substrate for laccase production by the well-known laccase producer Trametes versicolor ATCC 20869 under solid-state fermentation conditions was assessed. An attempt was made to improve the laccase production by T..

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Bioresource technology

Functionalized magnetic mesoporous silica nanoparticles: fabrication, laccase adsorption performance and direct laccase capture from Trametes versicolor fermentation broth.

A simple and highly efficient protocol using magnetic mesoporous silica nanoparticles (MMSNPs) with metal affinity ligands was developed to directly capture laccase from Trametes versicolor fermentation broth..

Energy & fatigue

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Protein expression and purification

Gene cloning and recombinant expression of a novel fungal immunomodulatory protein from Trametes versicolor.

Homology-based cloning was used to obtain a new gene (named FIP-tvc) from the genomic DNA of the Chinese traditional medicinal mushroom Trametes versicolor. FIP-tvc is a member of the fungal immunomodulatory protein family, is composed of 336bp encoding 111 amino acids, and is highly homologous with other fungal….

OncologyImmune support

Medium relevance

Zhu Ling · 2012 · Research Support, Non U.S. Gov'T · Genetics and molecular research: GMR

Genetic diversity of endangered Polyporus umbellatus from China assessed using a sequence-related amplified polymorphism technique.

Polyporus umbellatus (Pers.) Fries is an endangered medicinal fungus in China with in vivo anticancer activity, but its genetic information is lacking. Eight natural P..

Oncology

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Applied biochemistry and biotechnology

Heat shock treatment improves Trametes versicolor laccase production.

An efficient heat shock strategy has been developed to improve laccase production in submerged Trametes versicolor cultures. The optimized heat shock strategy consists of subjecting T..

Medium relevance

Lion's Mane · 2012 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Hericium erinaceus mushroom extracts protect infected mice against Salmonella Typhimurium-Induced liver damage and mortality by stimulation of innate immune cells.

The present study investigated the antibacterial effect of four extracts from the fruitbody of the edible medicinal mushroom Hericium erinaceus (hot water extract, HWE; microwave/50% ethanol extract, MWE; acid extract, ACE; and alkaline extract, AKE) against murine salmonellosis..

Immune supportGut & microbiomeLiver support

Medium relevance

Lion's Mane · 2012 · Research Support, Non U.S. Gov'T · Immunopharmacology and immunotoxicology

Hericium erinaceus suppresses LPS-induced pro-inflammation gene activation in RAW264.7 macrophages.

The aim of this study was to investigate the anti-inflammatory properties of each fraction of Hericium erinaceus (HE). The ethanol extract from HE was partitioned with different solvents in the order of increasing polarity..

Immune supportEnergy & fatigue

Medium relevance

Mesima · 2012 · Research Support, Non U.S. Gov'T · Chemico-biological interactions

Hispidin produced from Phellinus linteus protects against peroxynitrite-mediated DNA damage and hydroxyl radical generation.

Oxidative stress plays an important role in the progression of many chronic diseases including cardiovascular diseases, diabetes, cancer and neurodegenerative disorders..

OncologyCognition & nervesMetabolic health

Medium relevance

Mesima · 2012 · Research Support, Non U.S. Gov'T · BMC complementary and alternative medicine

Immunomodulatory effect of water soluble extract separated from mycelium of Phellinus linteus on experimental atopic dermatitis.

BACKGROUND: Complementary and alternative medicine (CAM) is becoming a popular treatment for modulating diverse immune disorders. Phellinus linteus (P.

OncologyImmune supportSkin & hydration

Medium relevance

Niu-Chang-Chih · 2012 · Comparative Study · Applied microbiology and biotechnology

In vitro and in vivo comparisons of the effects of the fruiting body and mycelium of Antrodia camphorata against amyloid β-protein-induced neurotoxicity and memory impairment.

Antrodia camphorata is a particular and precious medicinal mushroom, and its fruiting body was found to provide more efficient protection from oxidative stress and inflammation than its mycelium because of its higher content of triterpenoids, total phenols, and so on..

OncologyImmune supportCognition & nerves

Medium relevance

Niu-Chang-Chih · 2012 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

In vivo antitumor effects of 4,7-dimethoxy-5-methyl-1,3-benzodioxole isolated from the fruiting body of Antrodia camphorata through activation of the p53-mediated p27/Kip1 signaling pathway.

In this study, 4,7-dimethoxy-5-methyl-1,3-benzodioxole (SY-1) was isolated from three different sources of dried Antrodia camphorata (AC) fruiting bodies. AC is a medicinal mushroom that grows on the inner heartwood wall of Cinnamomum kanehirai Hay (Lauraceae), which is an endemic species that is used in Chinese….

OncologyImmune supportMetabolic healthGut & microbiome

Medium relevance

Maitake · 2012 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Isolation, purification and antioxidant activities of polysaccharides from Grifola frondosa.

The crude polysaccharides (GFP) were isolated from the fruiting bodies of Grifola frondosa and purified by DEAE cellulose-52 chromatography and Sephadex G-100 size-exclusion chromatography in that order. Three main fractions, GFP-1, GFP-2 and GFP-3, were obtained through the isolation and purification steps..

Immune supportLiver support

Medium relevance

Niu-Chang-Chih · 2012 · Research Support, Non U.S. Gov'T · Phytochemistry

Lanostane triterpenoids and sterols from Antrodia camphorata.

Four lanostane triterpenes, 3,7,11-trioxo-5α-lanosta-8,24(E)-dien-26-oic acid, methyl 11α-3,7-dioxo-5α-lanosta-8,24(E)-dien-26-oate, methyl 3,7,11,12,15,23-hexaoxo-5α-lanost-8-en-26-oate, and ethyl 3,7,11,12,15,23-hexaoxo-5α-lanost-8-en-26-oate, two sterols, (14α,22E)-14-hydroxyergosta-7,22-diene-3,6-dione and a….

Oncology

Medium relevance

Mesima · 2012 · Brief Report · Mycobiology

Neuraminidase Inhibitors from the Culture Broth of Phellinus linteus.

During the search for neuraminidase inhibitors from medicinal fungi, we found that the culture broth of Phellinus linteus exhibited potent inhibitory activity. Solvent partition, Sephadex LH-20 column chromatography, and high-performance liquid chromatography (HPLC) were performed for purification of two active….

Energy & fatigue

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Fungal biology

Nitrogen sources of Oligoporus placenta and Trametes versicolor evaluated in a 2(3) experimental plan.

Four full-factorial 2(3) experimental plans were applied to evaluate the nitrogen (N) sources of Oligoporus placenta and Trametes versicolor and their interaction with the atmospheric N(2)-assimilating bacterium Beijerinckia acida..

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Biodegradation

Optimisation of the operational conditions of trichloroethylene degradation using Trametes versicolor under quinone redox cycling conditions using central composite design methodology.

Extracellular radicals produced by Trametes versicolor under quinone redox cycling conditions can degrade a large variety of pollutant compounds, including trichloroethylene (TCE)..

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Applied biochemistry and biotechnology

Optimization of laccase production by Trametes versicolor cultivated on industrial waste.

Laccases are very interesting biocatalysts for several industrial applications. Its production by different white-rot fungi can be stimulated by a variety of inducing substrates, and the use of lignocellulosic wastes or industrial by-products is one of the possible approaches to reduce production costs..

Medium relevance

Maitake · 2012 · Research Support, Non U.S. Gov'T · Inflammation

Pharmacological and pharmacokinetic studies with agaricoglycerides, extracted from Grifola frondosa, in animal models of pain and inflammation.

The objective of the present study was to demonstrate the anti-inflammatory and antinociceptive properties of agaricoglycerides of the fermented mushroom of Grifola frondosa (AGF)..

OncologyImmune supportEnergy & fatigue

Medium relevance

Niu-Chang-Chih · 2012 · Research Support, Non U.S. Gov'T · Nutrition (Burbank, Los Angeles County, Calif.)

Polysaccharides from extracts of Antrodia camphorata mycelia and fruiting bodies modulate inflammatory mediator expression in mice with polymicrobial sepsis.

OBJECTIVES: Antrodia camphorata (AC) is a traditional Chinese medicine, and the polysaccharides contained within AC (AC-PSs) are reported to possess various biological functions..

OncologyImmune supportRespiratory

Medium relevance

Snow Fungus · 2012 · Research Support, Non U.S. Gov'T · Journal of radiation research

Protective Effect of Polysaccharides Isolated from Tremella fuciformis against Radiation-induced Damage in Mice

WTF-B, a type of water-soluble homogeneous polysaccharide, was isolated and purified from Tremella Fuciformis. To investigate the radioprotective effect of WTF-B, we employed a 30-day survival assay.

Immune supportMetabolic healthGut & microbiome

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Bioresource technology

Removal of monomer delignification products by laccase from Trametes versicolor.

The influence of a laccase from Trametes versicolor on the removal of phenolic monomers in liquid hot water pretreated wheat straw supernatants (LHW-S) was examined..

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Journal of hazardous materials

Removal of pharmaceuticals, polybrominated flame retardants and UV-filters from sludge by the fungus Trametes versicolor in bioslurry reactor.

Conventional wastewater treatments are inefficient in the removal of many organic pollutants. The presence of these contaminants in the final sludge represents a source of environmental pollution due to the increasing use of biosolids in land application..

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · TheScientificWorldJournal

Role of laccase and low molecular weight metabolites from Trametes versicolor in dye decolorization.

The studies regarding decolorization of dyes by laccase may not only inform about the possible application of this enzyme for environmental purposes, but also may provide important information about its reaction mechanism and the influence of several factors that could be involved..

Medium relevance

Turkey Tail · 2012 · Research Support, Non U.S. Gov'T · Bioresource technology

Simple fabrication of polymer-based Trametes versicolor laccase for decolorization of malachite green.

A highly efficient and stable biocatalyst (denoted D201_Lac) was fabricated by encapsulating Trametes versicolor laccase within a macroporous and strongly basic exchange resin D201 through a simple adsorption process..

Medium relevance

Zhu Ling · 2012 · Research Support, Non U.S. Gov'T · Glycobiology

Structure elucidation and immunological function analysis of a novel β-glucan from the fruit bodies of Polyporus umbellatus (Pers.) Fries.

β-Glucans derived from various sources such as yeast cell walls and medicinal mushrooms are considered as valuable biological response modifiers for their ability to enhance the activity of immune cells, aid in wound healing and help prevent infections..

Immune supportMetabolic healthSkin & hydration

Medium relevance

Maitake · 2012 · Research Support, Non U.S. Gov'T · Glycoconjugate journal

Structure of a β-glucan from Grifola frondosa and its antitumor effect by activating Dectin-1/Syk/NF-κB signaling.

A soluble homogeneous β-glucan, GFPBW1, with a molecular mass of 300 kDa was purified from the fraction of the fruit bodies of Grifola frondosa extracted with 5% NaOH..

OncologyImmune support

Medium relevance

Snow Fungus · 2012 · Research Support, Non U.S. Gov'T · Behavioural brain research

Tremella fuciformis enhances the neurite outgrowth of PC12 cells and restores trimethyltin-induced impairment of memory in rats via activation of CREB transcription and cholinergic systems.

The present study examined the effects of Tremella fuciformis (TF) on the learning and memory function and the neural activity in rats with trimethyltin (TMT)-induced memory deficits. The rats were administered saline or TF (TF 25, 50, 100 mg/kg, p.o.) daily for 21 days..

Immune supportCognition & nervesMetabolic health

Medium relevance

Niu-Chang-Chih · 2011 · English Abstract · Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

[Analyze on volatile compounds of Antrodia camphorata using HS-SPME-GC-MS].

OBJECTIVE: To analyze the volatile compounds of Antrodia camphorata in solid-state and submerged cultures. METHODS: A headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry(GC-MS) were used to evaluate the profile of the volatile compounds..

Medium relevance

Chaga · 2011 · English Abstract · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Protective effects and mechanism of Inonotus obliquus on asthmatic mice].

OBJECTIVE: To explore the protective effects and mechanism of ethanol extract of Inonotus obliquus (EEIO) injection on asthmatic mice. METHOD: OVA was injected intraperitoneally and inhaled to produce the asthmatic model.

Immune supportRespiratory

Medium relevance

Niu-Chang-Chih · 2011 · Other · Evidence-based complementary and alternative medicine: eCAM

A Preclinical Evaluation of Antrodia camphorata Alcohol Extracts in the Treatment of Non-Small Cell Lung Cancer Using Non-Invasive Molecular Imaging.

This study was carried out to provide a platform for the pre-clinical evaluation of anti-cancer properties of a unique CAM (complementary and alternative medicine) agent, Antrodia camphorata alcohol extract (ACAE), in a mouse model with the advantageous non-invasive in vivo bioluminescence molecular imaging….

OncologyImmune supportRespiratory

Medium relevance

Niu-Chang-Chih · 2011 · Other · Evidence-based complementary and alternative medicine: eCAM

An Extract of Antrodia camphorata Mycelia Attenuates the Progression of Nephritis in Systemic Lupus Erythematosus-Prone NZB/W F1 Mice.

Antrodia camphorata is used in folk medicine for the treatment of inflammation syndromes and liver-related diseases in Taiwan. The goal of this study was to evaluate the efficacy of the mycelial extract of A.

OncologyImmune supportLiver support

Medium relevance

Niu-Chang-Chih · 2011 · Research Support, Non U.S. Gov'T · Acta pharmacologica Sinica

Antcin A, a steroid-like compound from Antrodia camphorata, exerts anti-inflammatory effect via mimicking glucocorticoids.

AIM: To determine the active ingredient of Niuchangchih (Antrodia camphorata) responsible for its anti-inflammatory effects and the relevant molecular mechanisms. METHODS: Five major antcins (A, B, C, H, and K) were isolated from fruiting bodies of Niuchangchih..

Immune support

Medium relevance

Niu-Chang-Chih · 2011 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Antcin B and its ester derivative from Antrodia camphorata induce apoptosis in hepatocellular carcinoma cells involves enhancing oxidative stress coincident with activation of intrinsic and extrinsic apoptotic pathway.

The triterpenoids methylantcinate B (MAB) and antcin B (AB), isolated from the medicinal mushroom Antrodia camphorata, have been identified as strong cytotoxic agents against various type of cancer cells; however, the mechanisms of MAB- and AB-induced cytotoxicity have not been adequately explored..

OncologyEnergy & fatigueLiver support

Medium relevance

Niu-Chang-Chih · 2011 · Research Support, Non U.S. Gov'T · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Anti-metastatic activities of Antrodia camphorata against human breast cancer cells mediated through suppression of the MAPK signaling pathway.

The fermented culture broth of Antrodia camphorata (A. camphorata) has been shown to promote cell cycle arrest and apoptosis of human estrogen-nonresponsive MDA-MB-231 cells.

OncologySkin & hydration

Medium relevance

Mesima · 2011 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Anti-tumor effects of proteoglycan from Phellinus linteus by immunomodulating and inhibiting Reg IV/EGFR/Akt signaling pathway in colorectal carcinoma.

Proteoglycan (P1) purified from Phellinus linteus has been reported to have anti-disease activities. The objectives of our research were to determine the anti-tumor effect and possible mechanisms of P1 on human cancer cells..

OncologyImmune supportGut & microbiome

Medium relevance

Yellow Morel · 2011 · Research Support, Non U.S. Gov'T · Natural product research

Antioxidant and NF-κB inhibitory constituents isolated from Morchella esculenta.

Morchella esculenta Pers. (Morchellaceae) was investigated for its antioxidant activity by measuring the intracellular reactive oxygen species in HT-29 colon cancer cells..

OncologyEnergy & fatigueGut & microbiome

Medium relevance

Niu-Chang-Chih · 2011 · Research Support, Non U.S. Gov'T · International journal of gynecological cancer: official journal of the International Gynecological Cancer Society

Antrodia camphorata induces apoptosis and enhances the cytotoxic effect of paclitaxel in human ovarian cancer cells.

INTRODUCTION: Antrodia camphorata is a Chinese herb. Recently, several reports demonstrated that it had growth-inhibiting effects on some cancer cells.

OncologyEnergy & fatigue

Medium relevance

Turkey Tail · 2011 · Research Support, Non U.S. Gov'T · The Science of the total environment

Biodegradation of sulfamethazine by Trametes versicolor: Removal from sewage sludge and identification of intermediate products by UPLC-QqTOF-MS.

Degradation of the sulfonamide sulfamethazine (SMZ) by the white-rot fungus Trametes versicolor was assessed. Elimination was achieved to nearly undetectable levels after 20 h in liquid medium when SMZ was added at 9 mg L(-1).

Medium relevance

Turkey Tail · 2011 · Research Support, Non U.S. Gov'T · Bioresource technology

Biological pretreatment with a cellobiose dehydrogenase-deficient strain of Trametes versicolor enhances the biofuel potential of canola straw.

The use of Trametes versicolor as a biological pretreatment for canola straw was explored in the context of biofuel production. Specifically, the effects on the straw of a wild-type strain (52J) and a cellobiose dehydrogenase (CDH)-deficient strain (m4D) were investigated..

Metabolic health

Medium relevance

Turkey Tail · 2011 · Research Support, Non U.S. Gov'T · Applied microbiology and biotechnology

Ceramic honeycomb as support for covalent immobilization of laccase from Trametes versicolor and transformation of nuclear fast red.

The covalent immobilization of laccase on an inorganic ceramic support was investigated. The intention was to find a system of enzyme and reactor for a universal immobilization procedure.