MycoData

A comparative study was carried out on the chemical composition and nutritional value of six cultivated Lentinula edodes strains that are widely appreciated in China. The results demonstrated that all investigated L..

Gut & microbiome

High relevance

Reishi · 2021 · Journal Article · International journal of medicinal mushrooms

Chemical Compounds and Computational Prediction of Their Inhibitory Effects on the HIV-1 gp120 Receptor by Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), with Antler-Like Morphology of Fruiting Bodies.

In this study, crude extracts of Ganoderma lucidum (NGCs) were compared to the crude extracts of G. lucidum that has antler-like fruiting bodies (AGCs) for their cytotoxicity, inhibitory effects on the attachment of human immunodeficiency virus (HIV)-1 glycoprotein 120 (gp120) to cluster of differentiation 4 (CD4),….

OncologyImmune supportEnergy & fatigueRespiratory

High relevance

Almond Mushroom · 2021 · Journal Article · Chemistry & biodiversity

Chemically Sulfated Polysaccharides from Agaricus blazei Murill: Synthesis, Characterization and Anti-HIV Activity.

AIDS, caused by HIV-1, is one of the most dangerous infectious diseases in the world. Therefore, it is necessary to develop new drugs with more potent bioactivities, less toxicity and higher tolerability for controlling the viral load, particularly by using the raw materials that are widely available..

Immune supportRespiratory

High relevance

Cordyceps · 2021 · Research Article · The Science of the total environment

Chinese caterpillar fungus (Ophiocordyceps sinensis) in China: Current distribution, trading, and futures under climate change and overexploitation.

Chinese caterpillar fungus (Ophiocordyceps sinensis) is a precious traditional medicine which is mostly distributed on the Qinghai-Tibetan Plateau (QTP). Due to its medicinal values, it has become one of the most valuable biological commodities and widely traded in recent years worldwide..

High relevance

Shiitake · 2021 · Research Article · Journal of fungi (Basel, Switzerland)

Chromosome-Wide Characterization of Intragenic Crossover in Shiitake Mushroom, Lentinula edodes.

Meiotic crossover plays a critical role in generating genetic variations and is a central component of breeding. However, our understanding of crossover in mushroom-forming fungi is limited..

High relevance

Reishi · 2021 · Journal Article · International journal of biological macromolecules

Co-encapsulation of probiotic Lactobacillus acidophilus and Reishi medicinal mushroom (Ganoderma lingzhi) extract in moist calcium alginate beads.

Probiotic L. acidophilus La-14 cells were co-encapsulated with Ganoderma lingzhi extract to prolong the viability of the cells under simulated gastrointestinal (SGI) condition and to protect the active ingredients of Reishi mushroom during the storage period..

Gut & microbiome

High relevance

Reishi · 2021 · Journal Article · International journal of food science & technology

Comparative evaluation of physicochemical properties of Lingzhi (Ganoderma lucidum) as affected by drying conditions and extraction methods

Lingzhi (Ganoderma lucidum) is a high‐potential mushroom which is used as a dietary supplement or a source of nutrients and antioxidant agents. The aims were to investigate the effect of drying conditions (hot air and vacuum dry) and to compare the extraction methods of microwave‐assisted extraction (MAE) and pulsed….

Immune supportMetabolic health

High relevance

Cordyceps · 2021 · Journal Article · Phytomedicine: international journal of phytotherapy and phytopharmacology

Comparison of effects on colitis-associated tumorigenesis and gut microbiota in mice between Ophiocordyceps sinensis and Cordyceps militaris.

BACKGROUND: Gut microbiota plays an indispensable role in the treatment of inflammatory bowel disease (IBD) and colitis-associated cancer (CAC). As traditional medicinal fungi, previous studies have shown that Ophiocordyceps sinensis could better maintain intestinal health via promoting the growth of probiotics in….

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Cordyceps · 2021 · Research Article · ACS omega

Comparison of Ergosterol and Vitamin D2 in Mushrooms Agaricus bisporus and Cordyceps militaris Using Ultraviolet Irradiation Directly on Dry Powder or in Ethanol Suspension.

Vitamin D deficiency is a severe worldwide health issue. Edible mushrooms are an excellent vitamin D2 source and have gained popularity worldwide as a nutritional food..

Skin & hydration

High relevance

Cordyceps · 2021 · Journal Article · Journal of food biochemistry

Comparison of metabolism substances in Cordyceps sinensis and Cordyceps militaris cultivated with tussah pupa based on LC‐MS

The objective of our study was to compare the chemical composition of Cordyceps sinensis (C. sinensis) and Cordyceps militaris (C.

High relevance

Chaga · 2021 · Research Article · Journal of fungi (Basel, Switzerland)

Comparison of Polysaccharides Extracted from Cultivated Mycelium of Inonotus obliquus with Polysaccharide Fractions Obtained from Sterile Conk (Chaga) and Birch Heart Rot.

The polysaccharides of the sterile conk of Inonotus obliquus (Chaga) have demonstrated multiple bioactivities. The mycelium of this basidiomycete, obtained after submerged cultivation, has been considered a feasible alternative to the sterile conk for the production of polysaccharides..

Immune supportGut & microbiome

High relevance

Cordyceps · 2021 · Journal Article · Antonie van Leeuwenhoek

Complex microbial communities inhabiting natural Cordyceps militaris and the habitat soil and their predicted functions.

Cordyceps militaris is a traditional Chinese medicinal food that is challenging to quality maintaining while mass cultivation. Many studies have found that abundant microbes inhabit Ophiocordyceps sinensis and perform important functions for their host..

Gut & microbiome

High relevance

Shiitake · 2021 · Research Article · Mycobiology

Construction of a CRISPR/Cas9-Mediated Genome Editing System in Lentinula edodes.

CRISPR/Cas9 genome editing systems have been established in a broad range of eukaryotic species. Herein, we report the first method for genetic engineering in pyogo (shiitake) mushrooms (Lentinula edodes) using CRISPR/Cas9..

High relevance

Cordyceps · 2021 · Research Article · International journal of molecular sciences

Cordyceps militaris Immunomodulatory Protein Promotes the Phagocytic Ability of Macrophages through the TLR4-NF-κB Pathway.

Enhancing the phagocytosis of immune cells with medicines provides benefits to the physiological balance by removing foreign pathogens and apoptotic cells. The fungal immunomodulatory protein (FIP) possessing various immunopotentiation functions may be a good candidate for such drugs..

Immune support

High relevance

Cordyceps · 2021 · Research Article · Microorganisms

Culture Degeneration Reduces Sex-Related Gene Expression, Alters Metabolite Production and Reduces Insect Pathogenic Response in Cordyceps militaris.

Cordyceps militaris is an entomopathogenic ascomycete, known primarily for infecting lepidopteran larval (caterpillars) and pupal hosts. Cordycepin, a secondary metabolite produced by this fungus has anti-inflammatory properties and other pharmacological activities..

Immune support

High relevance

Cordyceps · 2021 · Research Article · International journal of molecular sciences

Cysteine-Rich Hydrophobin Gene Family: Genome Wide Analysis, Phylogeny and Transcript Profiling in Cordyceps militaris.

Hydrophobins are a family of small secreted proteins found exclusively in fungi, and they play various roles in the life cycle. In the present study, genome wide analysis and transcript profiling of the hydrophobin family in Cordyceps militaris, a well-known edible and medicinal mushroom, were studied..

High relevance

King Oyster · 2021 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Decontamination of Listeria monocytogenes in king oyster mushrooms (Pleurotus eryngii) by combined treatments with organic acids, nisin, and ultrasound

This study was conducted to evaluate the effectiveness of 1–3% organic acids alone or in combination with 0.1% nisin and/or 40 kHz ultrasound (US) on the reduction of Listeria monocytogenes in king oyster mushrooms stored at 25 °C. While L..

High relevance

Reishi · 2021 · Journal Article · International journal of medicinal mushrooms

Development and Optimization of the Triterpenoid and Sterol Production Process with Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum Strain G0017 (Agaricomycetes), in Liquid Submerged Fermentation at Large Scale.

Ganoderma lucidum mycelia are rich in active substances such as triterpenoids and sterols. However, reports on the development of effective submerged fermentation processes are lacking and the resulting total triterpene and sterol yield is still quite low.

High relevance

Reishi · 2021 · Research Article · Foods (Basel, Switzerland)

Differences in Antioxidants, Polyphenols, Protein Digestibility and Nutritional Profile between Ganoderma lingzhi from Industrial Crops in Asia and Ganoderma lucidum from Cultivation and Iberian Origin.

Carpophores of Ganoderma lingzhi (GZ) from industrial crops in China were analysed and compared with carpophores of three Iberian strains of cultivated Ganoderma lucidum (GL) (Aveiro, Madrid, Palencia) previously genetically characterized..

Gut & microbiome

High relevance

Cordyceps · 2021 · Journal Article · Natural product research

Doubled production of cordycepin analogs in cultured Cordyceps militaris by addition of Andrea droppings.

Cordyceps sinensis is a traditional Chinese medicine with various biological activities. With its limited natural supply, cultured C.

High relevance

Almond Mushroom · 2021 · Journal Article · Brazilian journal of biology = Revista brasleira de biologia

Effect of Agaricus blazei Murill on exploratory behavior of mice-model.

Increased anxiety and depressive symptoms have reported to be its association with long term illness. Because of having unwanted effects of newly available drugs, patients administering anxiolytic drugs usually discontinue the treatment before they are completely recovered..

Cognition & nerves

High relevance

Reishi · 2021 · Journal Article · International journal of medicinal mushrooms

Effect of Continuous Cropping Soil on the Biosynthesis of Bioactive Compounds and the Antioxidant Activity of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes).

Continuous monoculture can increase plant morbidity and reduce crop yields. However, the Ganoderma lucidum mushroom possesses unique nutrient acquisition methods and displays an altered response to the generation of reactive oxygen species (ROS).

Immune supportEnergy & fatigue

High relevance

Chaga · 2021 · Journal Article · Journal of ethnopharmacology

Effect of Inonotus obliquus (Fr.) Pilat extract on the regulation of glycolipid metabolism via PI3K/Akt and AMPK/ACC pathways in mice.

ETHNOPHARMACOLOGICAL RELEVANCE: Inonotus obliquus (Fr.) Pilat is a mushroom belonging to the family Hymenochaetaceae. It is popularly called the Chaga mushroom in Russian folk medicine and has been used as a traditional medicine to treat diabetes mellitus in Eastern European and Asian countries..

Metabolic healthLiver support

High relevance

Oyster Mushroom · 2021 · Journal Article · Journal of food processing and preservation

Effect of vacuum drying temperature and pressure on the drying and desorption characteristics, and lovastatin content of the oyster mushroom (Pleurotus ostreatus) slices

The aim of this study was to investigate the effect of vacuum drying conditions on the quality characteristics of oyster mushroom slices. The moisture desorption isotherms and changes in the lovastatin content of samples during drying were also determined..

Energy & fatigue

High relevance

Cordyceps · 2021 · Research Article · Microorganisms

Effects of Cordycepin in Cordyceps militaris during Its Infection to Silkworm Larvae.

Cordyceps militaris produces cordycepin, a secondary metabolite that exhibits numerous bioactive properties. However, cordycepin pharmacology in vivo is not yet understood.

High relevance

Shiitake · 2021 · Research Article · Foods (Basel, Switzerland)

Effects of Drying Process on the Volatile and Non-Volatile Flavor Compounds of Lentinula edodes.

In this study, fresh Lentinula edodes was dehydrated using freeze-drying (FD), hot-air drying (HAD), and natural drying (ND), and the volatile and non-volatile flavor compounds were analyzed. The drying process changed the contents of eight-carbon compounds and resulted in a weaker "mushroom flavor" for dried L..

High relevance

Cordyceps · 2021 · Journal Article · Pakistan journal of biological sciences: PJBS

Effects of Edible Insects on the Mycelium Formation of Cordyceps militaris.

Background and Objective: Cordyceps militaris is a potential edible medicinal mushroom which containing various biological activity such as anti-inflammatory, anti-ageing, anti-protozoal and anti-microbial. The compositions of C.

Immune supportGut & microbiome

High relevance

Shiitake · 2021 · Journal Article · International journal of medicinal mushrooms

Effects of Heat Stress and the Addition of Different Purines on the Synthesis of Eritadenine in Liquid Fermentation of Shiitake Culinary-Medicinal Mushroom, Lentinula edodes (Agaricomycetes).

This work aimed to explore the effects of heat stress and the addition of different purines (adenine, guanine, xanthine, and hypoxanthine) on the synthesis of eritadenine in liquid fermentation of Lentinula edodes. The L.

High relevance

Shiitake · 2021 · Journal Article · Journal of food processing and preservation

Effects of light irradiation on the textural properties and energy metabolism of postharvest shiitake mushrooms (Lentinula edodes)

Shiitake mushrooms (Lentinula edodes) easily get deteriorated along with softening during the storage. And energy dissipation is associated with senescence and deterioration of many agro‐products..

Energy & fatigue

High relevance

Chaga · 2021 · Research Article · Antioxidants (Basel, Switzerland)

Effects of pH and Temperature on Water under Pressurized Conditions in the Extraction of Nutraceuticals from Chaga (Inonotus obliquus) Mushroom.

Currently, there is increased interest in finding appropriate food-grade green extraction systems capable of extracting these bioactive compounds from dietary mushrooms for applications in various food, pharmacological, or nutraceutical formulations..

Energy & fatigue

High relevance

Chaga · 2021 · Journal Article · Journal of applied microbiology

Effects of supplementation of sea buckthorn press cake on mycelium growth and polysaccharides of Inonotus obliquus in submerged cultivation.

AIMS: Investigation of the influence of cultivation time and sea buckthorn press cake (Hippophaë rhamnoides) dosage on mycelium yield of Inonotus obliquus in submerged cultivation and on the yield, monomer composition, and macromolecular properties of the exopolysaccharides (EPS) from culture media and intracellular….

Immune support

High relevance

Cordyceps · 2021 · Research Article · Frontiers in psychiatry

Efficacy and Safety of Cordyceps militaris as an Adjuvant to Duloxetine in the Treatment of Insomnia in Patients With Depression: A 6-Week Double- Blind, Randomized, Placebo-Controlled Trial.

Background: Insomnia is a common clinical manifestation in patients with depression. Insomnia is not only a depression symptom but also an independent risk factor for recurrence.

Cognition & nerves

High relevance

Shiitake · 2021 · Research Article · Life (Basel, Switzerland)

Enhanced Expression of Thaumatin-like Protein Gene (LeTLP1) Endows Resistance to Trichoderma atroviride in Lentinula edodes.

Lentinula edodes (shiitake mushrooms) is heavily affected by the infection of Trichoderma atroviride, causing yield loss and decreases quality in shiitake mushrooms. The selection and breeding of fungal-resistant L.

High relevance

Cordyceps · 2021 · Journal Article · Enzyme and microbial technology

Enhancement of carotenoid production and its regulation in edible mushroom Cordyceps militaris by abiotic stresses.

Cordyceps militaris carotenoids are widely used as food additives, animal feed supplements, and so on. However, the biosynthetic pathway of carotenoids in C.

Energy & fatigueMetabolic health

High relevance

Cordyceps · 2021 · Journal Article · Biotechnology letters

Enzymatic characterization and validation of gene expression of phosphoglucomutase from Cordyceps militaris

The purification and characterization of PGM (Phosphoglucomutase) from Cordyceps militaris (C. militaris) was investigated.

High relevance

Cordyceps · 2021 · Journal Article · Biotechnology letters

Enzymatic characterization and validation of gene expression of phosphoglucomutase from Cordyceps militaris.

The purification and characterization of PGM (Phosphoglucomutase) from Cordyceps militaris (C. militaris) was investigated.

High relevance

Lion's Mane · 2021 · Journal Article · International journal of medicinal mushrooms

Evaluation of In Vitro Antioxidant and Antihyperglycemic Activities of Extracts from the Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes).

To obtain activated fractions, the ethanol extract (EE) of Hericium erinaceus was fractionated to get petroleum ether fraction (PEF), chloroform fraction (CF), ethyl acetate fraction (EAF) and n-butanol fraction (NF)..

Metabolic health

High relevance

Reishi · 2021 · Journal Article · Food & function

Extraction kinetics, physicochemical properties and immunomodulatory activity of the novel continuous phase transition extraction of polysaccharides from Ganoderma lucidum.

Ganoderma lucidum polysaccharides (GLP) possess remarkable bioactivity and have been studied widely. However, the application of new technologies in the polysaccharide extraction has not been investigated..

Immune support

High relevance

King Oyster · 2021 · Research Article · Microorganisms

Fermentation Supernatants of Pleurotus eryngii Mushroom Ameliorate Intestinal Epithelial Barrier Dysfunction in Lipopolysaccharide-Induced Caco-2 Cells via Upregulation of Tight Junctions.

In recent years, modulation of gut microbiota through prebiotics has garnered interest as a potential to ameliorate intestinal barrier dysfunction. The aim of the study was to examine the in vitro effect of fermentation supernatants (FSs) from rich in β-glucan Pleurotus eryngii mushrooms on the expression levels of….

Immune supportGut & microbiome

High relevance

Enoki · 2021 · Journal Article · International journal of biological macromolecules

Green fabrication of seedbed-like Flammulina velutipes polysaccharides-derived scaffolds accelerating full-thickness skin wound healing accompanied by hair follicle regeneration.

A novel seedbed-like scaffold was firstly fabricated by the "frozen sectioning" processing method using Flammulina velutipes as a raw material. The Flammulina velutipes polysaccharides scaffold is composed of a natural structure imitating the "ground" (connected and aligned hollow tubes with porous walls)..

Immune supportSkin & hydration

High relevance

Maitake · 2021 · Research Article · Nutrients

Grifola frondosa (Maitake) Extract Reduces Fat Accumulation and Improves Health Span in C. elegans through the DAF-16/FOXO and SKN-1/NRF2 Signalling Pathways.

In recent years, food ingredients rich in bioactive compounds have emerged as candidates to prevent excess adiposity and other metabolic complications characteristic of obesity, such as low-grade inflammation and oxidative status..

Immune supportMetabolic health

High relevance

Reishi · 2021 · Research Article · Foods (Basel, Switzerland)

Heat Treatment of Reishi Medicinal Mushroom (Ganoderma lingzhi) Basidiocarp Enhanced Its β-glucan Solubility, Antioxidant Capacity and Lactogenic Properties.

The effect of heat treatment on dried fruiting bodies of Reishi medicinal mushroom (Ganoderma lingzhi) is investigated. Control and samples treated for 20 min at temperatures of 70, 120, 150 and 180 °C were subjected for their free radical scavenging capacity, different glucans and total phenolic content….

Gut & microbiome

High relevance

Lion's Mane · 2021 · Research Article · Antioxidants (Basel, Switzerland)

Hericium erinaceus and Coriolus versicolor Modulate Molecular and Biochemical Changes after Traumatic Brain Injury.

Traumatic brain injury (TBI) is a major health and socioeconomic problem affecting the world. This condition results from the application of external physical force to the brain which leads to transient or permanent structural and functional impairments..

Immune supportCognition & nerves

High relevance

Lion's Mane · 2021 · Research Article · BMC complementary medicine and therapies

Hericium erinaceus mycelium ameliorate anxiety induced by continuous sleep disturbance in vivo.

BACKGROUND: Sleep disruption is a major public health issue and may increase the risk of mortality by ten-folds if an individual is sleeping less than 6 h per night. Sleep has changed dramatically during to the COVID-19 pandemic because COVID symptoms can lead to psychological distress including anxiety..

Cognition & nervesRespiratory

High relevance

Cordyceps · 2021 · Research Article · Journal of fungi (Basel, Switzerland)

Hydrophobin CmHYD1 Is Involved in Conidiation, Infection and Primordium Formation, and Regulated by GATA Transcription Factor CmAreA in Edible Fungus, Cordyceps militaris.

Hydrophobins are a family of small proteins exclusively secreted by fungi, and play a variety of roles in the life cycle. Cmhyd1, one of the hydrophobin class II members in Cordyceps militaris, has been shown to have a high transcript level during fruiting body development..

High relevance

Cordyceps · 2021 · Research Article · PeerJ

Identification and functional analysis of bacteria in sclerotia of Cordyceps militaris.

BACKGROUND: Cordyceps militaris is a fungus that parasitizes insects. Compounds from C.

Immune support

High relevance

Oyster Mushroom · 2021 · Research Article · Mycoscience

Identification and physiological function of one microRNA (Po-MilR-1) in oyster mushroom Pleurotus ostreatus.

MicroRNAs are essential regulators of gene expression and have been extensively studied in plants and animals; however, few reports have been published in mushrooms. Po-MilR-1 is a novel microRNA with a length of 22 bp in Pleurotus ostreatus..

High relevance

King Oyster · 2021 · Research Article · Journal of fungi (Basel, Switzerland)

Identification of the Antidepressant Function of the Edible Mushroom Pleurotus eryngii.

Pleurotus eryngii produces various functional molecules that mediate physiological functions in humans. Recently, we observed that P.

Cognition & nervesEnergy & fatigue

High relevance

Cordyceps · 2021 · Journal Article · Journal of ethnopharmacology

Immunostimulatory effects of the intracellular polysaccharides isolated from liquid culture of Ophiocordyceps sinensis (Ascomycetes) on RAW264.7 cells via the MAPK and PI3K/Akt signaling pathways.

ETHNOPHARMACOLOGICAL RELEVANCE: Chinese Cordyceps (DongChong XiaCao), a parasitic complex of a fungus Ophiocordyceps sinensis and a caterpillar, is a traditional Chinese medicine. Polysaccharides extracted from O.

Immune supportMetabolic health

High relevance

Enoki · 2021 · Journal Article · International journal of medicinal mushrooms

Improvement and Characterization of Naturally Occurring Folate Compounds in Fruiting Bodies of Culinary-Medicinal Winter Mushroom, Flammulina velutipes (Agaricomycetes).

Edible mushrooms are among food sources containing natural folate compounds. However, little is known about how the content of folates in edible mushrooms may be improved..

Energy & fatigue