MycoData

Snow Fungus · 2025 · Research Article · Ultrasonics sonochemistry

Effect of ultrasound pretreatment on the drying characteristics and quality of Tremella fuciformis under heat pump drying.

To enhance the heat pump drying (HPD) efficiency and quality of Tremella fuciformis (T. fuciformis), this study employed ultrasound pretreatment and evaluated its effects on drying behavior and product attributes at various ultrasound intensities [0.00 (the control group, CK), 0.20, 0.34, 0.54, and 0.74 W/g]..

Immune supportCognition & nervesGut & microbiomeSkin & hydration

Reishi · 2025 · Journal Article · Die Naturwissenschaften

Effects of Ganoderma lucidum polysaccharide on learning and memory impairment and intestinal flora in mice with D-galactose-induced aging.

Learning and memory impairment is one of the main manifestations of cognitive impairment. Gut flora can affect cognitive function and behavior through the gut-brain axis.

Immune supportEnergy & fatigueLiver supportSkin & hydration

Reishi · 2025 · Journal Article · Biomacromolecules

Ganoderma lucidum Polysaccharide/carboxymethyl Chitosan Hydrogels Modulate Macrophage Polarization for Wound Healing.

Wound healing remains a global challenge for clinical and experimental research. Hydrogels prepared from natural polysaccharides show great potential in the wound healing process..

Immune supportEnergy & fatigueSkin & hydration

Reishi · 2025 · Research Article · Frontiers in immunology

Ganoderma lucidum spore powder alleviates rheumatoid arthritis-associated pain hypersensitivity through inhibiting accumulation, N1 polarization, and ROS production of neutrophils in mice.

INTRODUCTION: Rheumatoid arthritis (RA) is a chronic condition characterized by joint pain that significantly impairs patients' work and daily lives. The limited understanding of the pathological mechanisms underlying RA-related pain poses challenges for effective clinical pain management..

OncologyImmune supportGut & microbiomeSkin & hydration

Chaga · 2025 · Research Article · Pharmaceuticals (Basel, Switzerland)

Integrating Network Pharmacology and Experimental Validation to Explore the Effect and Mechanism of Inonotus obliquus Polysaccharide in the Treatment of Rheumatoid Arthritis.

Background/Objectives: Rheumatoid arthritis (RA) is a chronic, systemic, and progressive autoimmune-inflammatory disease primarily affecting small joints. Inonotus obliquus polysaccharide (IOP) is the main component of the parasitic fungus obliquus, which has anti-tumor, anti-inflammatory, and antioxidant effects..

Reishi · 2025 · Research Article · Bioresources and bioprocessing

Light repair effect of polysaccharides component from white Ganoderma lucidum and Laminaria japonica fermentation broth attenuates epidermal barrier dysfunction via TRPV4-Keap-1/Nrf2 pathway.

Epidermal photoinflammation has emerged as an atypical pathological response that poses a growing global threat to human health and well-being. In this study, a polysaccharide component (named LJGp) was isolated from Laminaria japonica and white Ganoderma lucidum fermentation broth, and its reparative effects on….

OncologyImmune supportLiver supportSkin & hydration

Niu-Chang-Chih · 2025 · Research Article · International journal of molecular sciences

Natural Polysaccharide-Based Nanoparticles Enhance Intracellular Delivery and Cytotoxicity of Antrodia camphorata in Breast Cancer Cells.

Antrodia camphorata (AC), a medicinal fungus native to Taiwan, contains bioactive compounds such as triterpenoids with anticancer properties. However, their high lipophilicity results in poor aqueous solubility and limited bioavailability, restricting their therapeutic application..

Oyster Mushroom · 2025 · Research Article · Materials (Basel, Switzerland)

Optimized Microbial Scaffolds Immobilized with Pleurotus ostreatus and Aspergillus oryzae on Foaming Bacterial Cellulose.

In this study, we explored the development and characterization of fungus-immobilized foamed bacterial cellulose (FBC) scaffolds using Pleurotus ostreatus and Aspergillus oryzae..

Immune supportEnergy & fatigueMetabolic healthSkin & hydration

Enoki · 2025 · Journal Article · ACS applied materials & interfaces

Photo-Cross-Linked and Photothermal Flammulina velutipes Polysaccharide Hydrogel Loaded with Caffeic Acid-Copper Nanozyme for Diabetic Wound Healing.

Diabetic ulcers remain a persistent global health challenge. Developing therapeutic systems with antibacterial, antioxidant, anti-inflammatory, and pro-angiogenic properties presents a promising strategy for effectively and rapidly treating diabetic wounds and preventing the development of diabetic ulcers..

Immune supportGut & microbiomeSkin & hydration

Zhu Ling · 2025 · Journal Article · International journal of biological macromolecules

Polyporus Umbellatus polysaccharide ameliorates rheumatoid arthritis via inhibiting inflammation and regulating gut microbiota.

Rheumatoid arthritis (RA) is a chronic inflammatory joint disease that can cause cartilage and bone damage as well as a disability. Polyporus Umbellatus polysaccharide (PUP) as a β-glucan exhibit remarkable anti-inflammatory activity..

Oyster Mushroom · 2025 · Research Article · Pharmaceutics

Production of Myco-Nanomaterial Products from Pleurotus ostreatus (Agaricomycetes) Mushroom via Pyrolysis.

Background: The study aimed to develop a sustainable method for producing myco-nanomaterials, particularly fluorescent carbon nanodots (CNDs), from freeze-dried Pleurotus ostreatus (Agaricomycetes) mushroom powder via pyrolysis..

Lion's Mane · 2025 · Journal Article · Carbohydrate polymers

Self-assembled near-infrared-photothermal antibacterial Hericium erinaceus β-glucan/tannic acid/Fe (III) hydrogel for accelerating infected wound healing

Bacterial infection severely hinders skin wound healing, highlighting the critical application value of developing antibacterial and anti-inflammatory hydrogel dressings..

Lion's Mane · 2025 · Journal Article · Carbohydrate polymers

Self-assembled near-infrared-photothermal antibacterial Hericium erinaceus β-glucan/tannic acid/Fe (III) hydrogel for accelerating infected wound healing.

Bacterial infection severely hinders skin wound healing, highlighting the critical application value of developing antibacterial and anti-inflammatory hydrogel dressings..

Immune supportGut & microbiomeLiver supportSkin & hydration

Snow Fungus · 2025 · Journal Article · Langmuir: the ACS journal of surfaces and colloids

Soy Protein Isolate/Tremella Fuciformis Polysaccharide Complex-Stabilized High Internal Phase Pickering Emulsions: Andrographolide Delivery, Digestive Behavior, and 3D Printability.

The development of advanced bioactive delivery systems is critical for enhancing nutraceutical stability, controlled release, and functional food design. This study presented the fabrication of high internal phase Pickering emulsions (HIPPEs) stabilized by soy protein isolate (SPI) and Tremella fuciformis….

Energy & fatigueMetabolic healthGut & microbiomeSkin & hydration

Reishi · 2025 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Structural characterisation and cholesterol and bile salts adsorption properties of Ganoderma lucidum dietary fiber

This study prepared Ganoderma lucidum insoluble dietary fiber (GIDF) and soluble dietary fiber (GSDF) via enzymatic methods. The structural and physicochemical properties of GIDF and GSDF were systematically characterized using scanning electron microscopy (SEM), Fourier-transform infrared (FTIR) spectroscopy, X-ray….

Reishi · 2025 · Journal Article · Carbohydrate polymers

Structural insights into polysaccharides in Ganoderma lucidum cell walls by solid-state NMR

Ganoderma lucidum is a medicinal mushroom long esteemed in Asian traditional medicine for its health-promoting and longevity-enhancing properties. It contains over 400 bioactive compounds, among which its polysaccharides (GLPs) are especially significant due to their diverse biological functions..

Reishi · 2025 · Journal Article · Carbohydrate polymers

Structural insights into polysaccharides in Ganoderma lucidum cell walls by solid-state NMR.

OncologyImmune supportGut & microbiomeSkin & hydration

Reishi · 2025 · Research Article · Scientific reports

Study on the anti-tumor effect of Wall-broken ganoderma lucidum spore powder on papillary thyroid cancer.

Wall-broken Ganoderma lucidum spore powder (BGLSP), a traditional Chinese medicinal substance, contains bioactive triterpenoids with anti-tumor potential. However, its efficacy and mechanisms against papillary thyroid cancer (PTC) remain unclear..

Cognition & nervesEnergy & fatigueSkin & hydration

Shiitake · 2025 · Preprint · journal metadata

Sustainable Memristors from Shiitake Mycelium for High-Frequency Bioelectronics

Neuromorphic computing, inspired by the structure of the brain, offers advantages in parallel processing, memory storage, and energy efficiency. However, current semiconductor-based neuromorphic chips require rare-earth materials and costly fabrication processes, whereas neural organoids need complex bioreactor….

Shiitake · 2025 · Research Article · Toxics

The Toxicological Impact of the Ultraviolet Filter Oxybenzone on Antioxidant Profiles in In Vitro Cultures of Lentinula edodes.

A detailed understanding of the toxic effects of organic UV filters, such as oxybenzone, on living organisms is crucial for assessing the feasibility of bioremediation methods..

OncologyImmune supportSkin & hydration

Oyster Mushroom · 2025 · Journal Article · International journal of biological macromolecules

The use of Pleurotus ostreatus by-products for the preparation of a gel-like polysaccharide with bioactive properties.

The mushroom Pleurotus ostreatus is widely produced in Brazil and its stipes are discarded before commercialization. In the present study, this agricultural fungal waste (mushroom stipes), was analyzed by preparing an aqueous extract and obtaining the polysaccharides by ethanol precipitation (POS-extract)..

Cognition & nervesEnergy & fatigueSkin & hydration

Lion's Mane · 2025 · Research Article · Journal of fungi (Basel, Switzerland)

Two-Dimensional Chromatographic Isolation of High Purity Erinacine A from Hericium erinaceus.

A simple and robust two-dimensional chromatographic fractionation protocol for the isolation of the neuroprotective compound erinacine A from Hericium erinaceus is proposed. This production platform yielded 19.4 mg of erinacine A from approximately 130 g of mushroom material, with a chromatographic purity of 97.4%..

Energy & fatigueSkin & hydration

Oyster Mushroom · 2025 · Journal Article · World J Microbiol Biotechnol

Underlying the early signaling and gene expression of Pleurotus ostreatus mycelia during injury response

Plants and animals have demonstrated conserved damage defense systems, but the injury response mechanisms in fungi remain largely unexplored. In this study, we investigate the early defensive mechanisms activated by mechanical damage in the basidiomycota Pleurotus ostreatus..

Energy & fatigueSkin & hydration

Oyster Mushroom · 2025 · Journal Article · World journal of microbiology & biotechnology

Underlying the early signaling and gene expression of Pleurotus ostreatus mycelia during injury response.

Snow Fungus · 2024 · Journal Article · International journal of biological macromolecules

Cuttlefish ink-derived melanin nanoparticle-embedded tremella fuciformis polysaccharide hydrogels for the treatment of MRSA-infected diabetic wounds.

Diabetic wounds arise great attention as they are difficult to heal and easily suffer from serious bacterial infection. However, the overuse of antibiotics increases the resistance of bacteria and makes common drugs ineffective..

Liver supportSkin & hydration

Shiitake · 2024 · Journal Article · Journal of microbiological methods

Developing fish oil emulsion gel enriched with Lentinula edodes single cell protein and its effect on controlling the growth of Acinetobacter baumannii.

In this study, the characterization of fish oil (FO) emulsion gel (EGEL) containing single cell protein (SCP) produced from Lentinula edodes (L. edodes) and its potential inhibition against Acinetobacter baumannii (A.

Enoki · 2024 · Research Article · Foods (Basel, Switzerland)

Effect of Flammulina velutipes Soluble Dietary Fiber on Dough Processing Characteristics and Micro-Fermented Dried Noodles Quality Properties.

Our research focused on the integration of Flammulina velutipes soluble dietary fiber (Fv-SDF) into wheat flour during the production of dried noodles, delving into the impact of different addition ratios of Fv-SDF on both dough processing characteristics and the quality of the micro-fermented dried noodles..

Snow Fungus · 2024 · Research Article · Current research in food science

Effect of heat pump drying temperature on moisture migration characteristics and quality of instant Tremella fuciformis.

Low-field nuclear magnetic resonance (LF-NMR) was used to analyze the moisture migration characteristics and water distribution of instant Tremella fuciformis (ITF) during heat pump drying at 35 °C, 45 °C and 55 °C..

Chaga · 2024 · Journal Article · Chemistry & biodiversity

Effects of Chemical Modification on the Structure and Biological Activities of Polysaccharides Extracted from Inonotus Obliquus by Microwave.

A novel polysaccharide, Inonotus obliquus polysaccharide (IOP), was extracted using a microwave extraction method and subsequently subjected to modifications through sulfation, carboxymethylation, phosphorylation, and acetylation..

Snow Fungus · 2024 · Journal Article · International journal of biological macromolecules

Efficient conversion of cane molasses into Tremella fuciformis polysaccharides with enhanced bioactivity through repeated batch culture.

Tremella fuciformis polysaccharide (TFPS) is a natural mushroom mucopolysaccharide widely used in health foods, medical care, cosmetic and surgical materials. In this study, we developed an efficient strategy for the repeated batch production of highly bioactive TFPS from the agro-industrial residue cane molasses..

OncologyImmune supportSkin & hydration

Reishi · 2024 · Journal Article · International journal of biological macromolecules

Electrochemiluminescence assay for the impact of Ganoderma lucidum polysaccharides on resisting arsenic-induced apoptosis.

Ganoderma lucidum (G. lucidum) is a traditional edible fungus with strong medicinal value.

OncologyEnergy & fatigueSkin & hydration

Turkey Tail · 2024 · Journal Article · Journal of biotechnology

Enhancement of the biological activity of hydroxytyrosol through its oxidation by laccase from Trametes versicolor.

The laccase-catalyzed oxidation of hydroxytyrosol (HT) towards the formation of its bioactive oligomer derivatives was investigated. The biocatalytic oligomerization was catalyzed by laccase from Trametes versicolor in aqueous or various water-miscible organic solvents and deep eutectic solvent (DES)-based media..

Immune supportEnergy & fatigueSkin & hydration

Niu-Chang-Chih · 2024 · Journal Article · Innovative Food Science and Emerging Technologies

Enhancing submerged fermentation of Antrodia camphorata by low-frequency alternating magnetic field

This work aimed to investigate the impact of low-frequency (30–300 kHz) alternating magnetic field (LF-AMF) on enhancing submerged fermentation of Antrodia camphorata (A. camphorata), a basidiomycete fungus..

Oyster Mushroom · 2024 · Research Article · Foods (Basel, Switzerland)

Fish Fillet Analogue Using Formulation Based on Mushroom (Pleurotus ostreatus) and Enzymatic Treatment: Texture, Sensory, Aromatic Profile and Physicochemical Characterization.

The growing demand for alternative sources of non-animal proteins has stimulated research in this area. Mushrooms show potential in the innovation of plant-based food products..

Reishi · 2024 · Journal Article · Fitoterapia

Five undescribed meroterpenoids from Ganoderma lucidum and their inhibitory activities against renal fibrosis.

Five undescribed meroterpenoids, baosglucidnes A - E (1-5), were isolated from the fruiting bodies of Ganoderma lucidum. Among them, baosglucidne B (2) as a racemic mixture was obtained.

Immune supportEnergy & fatigueMetabolic healthSkin & hydration

Reishi · 2024 · Journal Article · International journal of biological macromolecules

Ganoderma lucidum polysaccharide hydrogel accelerates diabetic wound healing by regulating macrophage polarization.

Impaired macrophage polarization or the high levels of reactive oxygen species (ROS) produced by high glucose conditions and bacterial infection are the primary factors that make healing diabetic wounds difficult..

Lion's Mane · 2024 · Journal Article · International journal of biological macromolecules

Hericium erinaceus β-glucan/tannic acid hydrogels based on physical cross-linking and hydrogen bonding strategies for accelerating wound healing.

The majority of natural fungal β-glucans exhibit diverse biological functionalities, such as immunomodulation and anti-inflammatory effects, attributed to their distinctive helix or highly branched conformation This study utilized β-glucan with helix conformation and high-viscosity extracted from Hericium erinaceus,….

Metabolic healthSkin & hydration

Chaga · 2024 · Journal Article · Food chemistry

How lignocellulose degradation can promote the quality and function of dietary fiber from bamboo shoot residue by Inonotus obliquus fermentation.

Lignocellulose constitutes the primary component of dietary fiber. We assessed how fermenting bamboo shoot residue with the medicinal white-rot fungus Inonotus obliquus affected the yield, composition, and functional attributes of dietary fiber by altering bamboo shoot residue lignocellulose's spatial structure and….

Metabolic healthSkin & hydration

Snow Fungus · 2024 · Journal Article · Food chemistry

Improvement of soluble dietary fiber quality in Tremella fuciformis stem by steam explosion technology: An evaluation of structure and function.

Edible fungi by-products are rich in dietary fiber (DF). In this study, we used steam explosion (SE) to modify Tremella fuciformis (T.

Oyster Mushroom · 2024 · Research Article · RSC advances

In silico evaluation of potential breast cancer receptor antagonists from GC-MS and HPLC identified compounds in Pleurotus ostreatus extracts.

Introduction: Pharmacotherapeutic targets for breast cancer include the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor (EGFR). Inhibitors of these receptors could be interesting therapeutic candidates for the treatment and management of breast cancer (BC)..

OncologySkin & hydration

Turkey Tail · 2024 · Research Article · Scientific reports

In-vivo and in-vitro wound healing and tissue repair effect of Trametes versicolor polysaccharide extract.

Regarding different medical benefits of fungi, using the medical mushroom extracts as wound-healing agents is gaining popularity. This study, evaluated the wound healing characteristics of Trametes versicolor..

Snow Fungus · 2024 · Research Article · Molecules (Basel, Switzerland)

iTRAQ-Based Proteomic Profiling of Skin Aging Protective Effects of Tremella fuciformis-Derived Polysaccharides on D-Galactose-Induced Aging Mice.

In the present study, a heteromannan primarily composed of mannose, fucose, xylose, glucose, and arabinose at a molar ratio of 4.78:1.18:1:0.82:0.11 containing a low proportion of glucuronic acid with weight-average molecular weights of 3.6 × 106 Da, named NTP, was prepared from the fruiting body of Tremella….

Energy & fatigueSkin & hydration

Oyster Mushroom · 2024 · Research Article · Foods (Basel, Switzerland)

Optimization of Mushroom (Agaricus bisporus and Pleurotus ostreatus) By-Products Processing for Prospective Functional Flour Development.

Stems are a major by-product of mushroom production. This study optimizes the transformation of Agaricus bisporus stems (ABS) and Pleurotus ostreatus stems (POS) into flour.

OncologyImmune supportGut & microbiomeSkin & hydration

Oyster Mushroom · 2024 · Journal Article · Environmental pollution (Barking, Essex: 1987)

Pleurotus ostreatus polysaccharide-mediated modulation of skin damage caused by microcystin-LR in tadpoles.

In this study, we aimed to evaluate the effect of dietary supplementation with edible mushroom (Pleurotus ostreatus)-derived polysaccharides on microcystin leucine-arginine (MC-LR)-induced skin damage in Pelophylax nigromaculatus tadpoles..

Metabolic healthSkin & hydration

Maitake · 2024 · Journal Article · Journal of food science

Positive effect of peptide-calcium chelates from Grifola frondosa on a mouse model of senile osteoporosis.

Calcium supplementation has been shown to be efficacious in mitigating the progression of senile osteoporosis (SOP) and reducing the incidence of osteoporotic fractures resulting from prolonged calcium shortage..

Snow Fungus · 2024 · Journal Article · International journal of biological macromolecules

Pressure-controlled steam explosion as pretreatment for efficient extraction of Tremella fuciformis polysaccharide: Structure and bioactivity.

Tremella fuciformis (TF) is a mushroom with rich nutritional and medicinal value. This study aimed to develop an efficient extraction technique for TF polysaccharide (TFP) to enhance its health benefits..

Immune supportEnergy & fatigueMetabolic healthSkin & hydration

Chaga · 2024 · Research Article · Heliyon

Protective effect of Inonotus obliquus polysaccharide on MGO-induced nonenzymatic glycation fibroblasts.

BACKGROUND: The nonenzymatic glycation of fibroblasts causes functional downregulation and behavioral disorders in the skin. METHODS: To investigate the effect of Inonotus obliquus on the nonenzymatic glycation of skin, we examined the inhibition of advanced glycation end products (AGEs) using four extraction methods:….

Enoki · 2024 · Journal Article · International journal of biological macromolecules

Study on the physicochemical properties and antioxidant activities of Flammulina velutipes polysaccharide under controllable ultrasonic degradation based on artificial neural network.

The polysaccharide fraction (FVP2) with molecular weight of 1525.09 kDa and intrinsic viscosity of 3.43 dL/g was isolated and purified from Flammulina velutipes (F..