MycoData

Oyster Mushroom · 2021 · Journal Article · Journal of food processing and preservation

Effect of vacuum drying temperature and pressure on the drying and desorption characteristics, and lovastatin content of the oyster mushroom (Pleurotus ostreatus) slices

The aim of this study was to investigate the effect of vacuum drying conditions on the quality characteristics of oyster mushroom slices. The moisture desorption isotherms and changes in the lovastatin content of samples during drying were also determined..

Shiitake · 2021 · Journal Article · Journal of food processing and preservation

Effects of light irradiation on the textural properties and energy metabolism of postharvest shiitake mushrooms (Lentinula edodes)

Shiitake mushrooms (Lentinula edodes) easily get deteriorated along with softening during the storage. And energy dissipation is associated with senescence and deterioration of many agro‐products..

Chaga · 2021 · Research Article · Antioxidants (Basel, Switzerland)

Effects of pH and Temperature on Water under Pressurized Conditions in the Extraction of Nutraceuticals from Chaga (Inonotus obliquus) Mushroom.

Currently, there is increased interest in finding appropriate food-grade green extraction systems capable of extracting these bioactive compounds from dietary mushrooms for applications in various food, pharmacological, or nutraceutical formulations..

Cordyceps · 2021 · Journal Article · Enzyme and microbial technology

Enhancement of carotenoid production and its regulation in edible mushroom Cordyceps militaris by abiotic stresses.

Cordyceps militaris carotenoids are widely used as food additives, animal feed supplements, and so on. However, the biosynthetic pathway of carotenoids in C.

Cognition & nervesEnergy & fatigue

King Oyster · 2021 · Research Article · Journal of fungi (Basel, Switzerland)

Identification of the Antidepressant Function of the Edible Mushroom Pleurotus eryngii.

Pleurotus eryngii produces various functional molecules that mediate physiological functions in humans. Recently, we observed that P.

Enoki · 2021 · Journal Article · International journal of medicinal mushrooms

Improvement and Characterization of Naturally Occurring Folate Compounds in Fruiting Bodies of Culinary-Medicinal Winter Mushroom, Flammulina velutipes (Agaricomycetes).

Edible mushrooms are among food sources containing natural folate compounds. However, little is known about how the content of folates in edible mushrooms may be improved..

Immune supportCognition & nervesEnergy & fatigue

Lion's Mane · 2021 · Research Article · Antioxidants (Basel, Switzerland)

Key Mechanisms and Potential Implications of Hericium erinaceus in NLRP3 Inflammasome Activation by Reactive Oxygen Species during Alzheimer's Disease.

Alzheimer's disease (AD) is the principal cause of dementia, and its incidence increases with age. Altered antioxidant systems and inflammation have an important role in the etiology of neurodegenerative disorders..

Shiitake · 2021 · Research Article · Journal of food science and technology

Lentinula edodes mushroom as an ingredient to enhance the nutritional and functional properties of cereal bars.

Lentinula edodes (shiitake) is the second most cultivated edible mushroom in the world; it has low lipid contents, high protein and it is source of vitamins and minerals. This study aimed to develop and to evaluate two sweet and two salty food bars containing shiitake..

Shiitake · 2021 · Research Article · Biomolecules

Metabolic Profiles, Bioactive Compounds, and Antioxidant Capacity in Lentinula edodes Cultivated on Log versus Sawdust Substrates.

Lentinula edodes (shiitake) is a popular nutritious edible mushroom with a desirable aroma and flavor. Traditional cultivation of L.

Energy & fatigueGut & microbiome

Shiitake · 2021 · Journal Article · Journal of medicinal food

Nematicidal Effect of Shiitake (Lentinula edodes) Extracts Against Haemonchus contortus.

During the previous decades, the indiscriminate use of anthelmintics for the control of gastrointestinal nematodes has generated anthelmintic resistance in different parts of the world. It is necessary to search for new sustainable control alternatives, such as the use of extracts from plants and edible mushrooms..

Chaga · 2021 · Journal Article · Journal of the science of food and agriculture

Production of phenolic compounds and antioxidant activity via bioconversion of wheat straw by Inonotus obliquus under submerged fermentation with the aid of a surfactant

BACKGROUND: This study investigated the effect of surfactants on wheat straw biodegradation and the growth‐associated generation of exo‐ and endo‐phenolic compounds (EPC and IPC) and antioxidant activity expression by liquid‐cultured Inonotus obliquus, an edible and medicinal mushroom, also known as a white rot….

Chaga · 2021 · Journal Article · Journal of the science of food and agriculture

Production of phenolic compounds and antioxidant activity via bioconversion of wheat straw by Inonotus obliquus under submerged fermentation with the aid of a surfactant.

BACKGROUND: This study investigated the effect of surfactants on wheat straw biodegradation and the growth-associated generation of exo- and endo-phenolic compounds (EPC and IPC) and antioxidant activity expression by liquid-cultured Inonotus obliquus, an edible and medicinal mushroom, also known as a white rot….

Shiitake · 2021 · Journal Article · Journal of food science

Relationship between flavor and energy status in shiitake mushroom (Lentinula edodes) harvested at different developmental stages.

To understand the relationship between flavor and energy, the flavor, energy, and enzyme activity related to energy metabolism in shiitake mushrooms harvested at different developmental stages were investigated..

Immune supportEnergy & fatigue

Lion's Mane · 2021 · Journal Article · International journal of biological macromolecules

Structural characterization of enzymatic modification of Hericium erinaceus polysaccharide and its immune-enhancement activity.

In this study, the enzyme degradation of Hericium erinaceus polysaccharide (HEP) was successfully modified with endo-rhamnosidase to obtain the enzymatic hydrolysis of Hericium erinaceus polysaccharide product (EHEP)..

Immune supportEnergy & fatigueMetabolic health

Cordyceps · 2021 · Journal Article · International journal of biological macromolecules

Structure analysis and antioxidant activity of polysaccharide-iron (III) from Cordyceps militaris mycelia.

Iron-enriched Cordyceps militaris was obtained by adding FeSO4 solution to the mycelia for biotransformation. The polysaccharide-iron (III) was extracted by water extraction and alcohol precipitation.

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Chaga · 2021 · Research Article · Food science & nutrition

The difference of regulatory effect of two Inonotus obliquus extracts on high-fat diet mice in relation to the fatty acid elongation function of gut microbiota.

Obesity is a disease that causes metabolic disorders in the human body and is closely related to intestinal microbes. This experiment compares the therapeutic effects of two Inonotus obliquus extracts on high-fat diet (HFD) mice and explores the effects and mechanisms of intestinal flora and its metabolites..

Immune supportEnergy & fatigueSkin & hydration

Snow Fungus · 2021 · Journal Article · Journal of cosmetic dermatology

Tremella fuciformis polysaccharides inhibit UVA-induced photodamage of human dermal fibroblast cells by activating up-regulating Nrf2/Keap1 pathways.

BACKGROUND: UVA radiation can cause skin oxidative stress. Tremella fuciformis polysaccharides (TFPS) are the main active ingredient in Tremella.

OncologyEnergy & fatigueSkin & hydration

Yellow Morel · 2021 · Journal Article · Preparative biochemistry & biotechnology

Utilization of Morchella esculenta-mediated green synthesis golden nanoparticles in biomedicine applications.

This study aimed to synthesize gold nanoparticles (AuNPs) by hot water extract in room conditions using edible Morchella esculenta (ME) and investigate the bioactive properties of the synthesized Morchella esculenta-based gold nanoparticles (ME-AuNPs)..

Cognition & nervesEnergy & fatigue

Lion's Mane · 2026 · Preprint · journal metadata

A randomized, double□blind, placebo□controlled study evaluating the impact of Hericium erinaceus (Lion’s Mane) on cognitive performance and subjective wellbeing

Hericium erinaceus (Lion’s Mane) is a functional mushroom with a long history of culinary and traditional use, as well as potential neurotrophic and mood□modulating properties. Evidence for its effects on cognitive performance under real□world conditions, however, remains limited..

Shiitake · 2026 · Preprint · journal metadata

Regulatory Mechanism of Iron, Potassium, and Manganese on the Mycelial Growth of Lentinula edodes Revealed by Transcriptome Analysis

Lentinula edodes (L. edodes) is a significant edible and medicinal mushroom with essential nutrient elements for its growth, including Fe²⁺, K⁺, and Mn²⁺.

OncologyImmune supportEnergy & fatigueMetabolic health

Reishi · 2025 · Preprint · journal metadata

Multi-omics analysis reveals inhibition of osteosarcoma progression by sporoderm-removed Ganoderma lucidum spores via targeting glycerophospholipid and fatty acid Metabolism

Abstract Osteosarcoma (OS) is a severe malignancy affecting children and adolescents, with limited effective treatments leading to poor outcomes. This study explored the potential of sporoderm-removed Ganoderma lucidum spores (RGLS) as a novel therapeutic agent against OS and elucidated its mechanism of action..

OncologyImmune supportEnergy & fatigueRespiratory

Reishi · 2025 · Preprint · journal metadata

Synergistic Anti-Tumor and Immunomodulatory Effects of Sporoderm-Removed Ganoderma Lucidum Spore Powder and Anti-PD-L1 Antibody in Lung Cancer Mice

Abstract Background The therapeutic efficacy of PD-1/PD-L1 inhibitors in lung cancer management remains suboptimal. Sporoderm-removed Ganoderma Lucidum Spore Powder (RGLS), an immunostimulant, has been shown to amplify the anti-tumor effects of anti-PD-L1 antibodies (αPD-L1)..

Energy & fatigueMetabolic healthLiver support

Shiitake · 2025 · Preprint · journal metadata

The alterations of the synthetic pathway and metabolic flux of auxin indole-3-acetic acid (IAA) govern thermotolerance in Lentinula edodes mycelia subjected to heat stress

ABSTRACT Heat stress poses a significant constraint on the annual production of Lentinula edodes(L. edodes), a challenge that has been intensified by global warming.

OncologyEnergy & fatigueMetabolic healthRespiratory

Cordyceps · 2020 · Review · Sheng wu gong cheng xue bao = Chinese journal of biotechnology

[Advances in biosynthesis of cordycepin from Cordyceps militaris].

Cordycepin as the main active ingredient of Cordyceps militaris, a traditional medicinal fungus in China, has many physiological functions such as anti-cancer, anti-tumor and anti-virus activity. The most potential route for effective cordycepin production has been considered as liquid fermentation of C..

OncologyImmune supportCognition & nervesEnergy & fatigue

Lion's Mane · 2017 · Review · International journal of biological macromolecules

Structures, biological activities, and industrial applications of the polysaccharides from Hericium erinaceus (Lion's Mane) mushroom: A review.

Hericium erinaceus (Bull.) Pers., also known as Yamabushitake, Houtou and Lion's Mane, is capable of fortifying the spleen and nourishing the stomach, tranquilizing the mind, and fighting cancer. Over the past decade, it has been demonstrated that H..

OncologyEnergy & fatigueSkin & hydration

Reishi · 2026 · Research Article · Clinical, cosmetic and investigational dermatology

A Ganoderma lucidum Extract Improves Mitochondrial Function in Aging Skin and Promotes Wound Healing.

PURPOSE: This study investigates whether Ganoderma lucidum extract (GLE) can enhance mitochondrial function to promote wound healing in aging skin. METHODS: Natural senescent human foreskin fibroblasts (BJ) were treated with varying concentrations of GLE, and safe concentrations were determined using the cell counting….

Niu-Chang-Chih · 2026 · Journal Article · Angewandte Chemie (International ed. in English)

A Unique CYP450 Enzyme Unlocks Antrodia Camphorata Lanostane Triterpenoid Diversity Through Oxidation and Skeletal Rearrangement.

Lanostane triterpenoids, key therapeutic components of medicinal mushrooms, such as rare Antrodia camphorata, face heterologous biosynthesis barriers due to the lack of enzymes for essential C21/C15 oxidation and skeletal rearrangement, limiting access to these rare therapeutics..

OncologyImmune supportEnergy & fatigueRespiratory

Reishi · 2026 · Research Article · Discover oncology

Additive anti-tumor and immunomodulatory effects of Sporoderm-removed Ganoderma lucidum spore powder and anti-PD-L1 antibody in lung cancer mice.

BACKGROUND: The therapeutic efficacy of programmed cell death-1 (PD-1)/programmed cell death ligand-1 (PD-L1) inhibitors in lung cancer management remains suboptimal..

Cordyceps · 2026 · Research Article · Biology

Analysis of Codon Usage Bias Between Entomopathogenic Fungus Ophiocordyceps sinensis and Its Host, Thitarodes xiaojinensis.

Ophiocordyceps sinensis, a fungus parasitic on insects, attracts interest due to its unique medicinal applications and complex ecological interactions. The potential relationship between codon usage bias and the parasitic relationship between O..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Almond Mushroom · 2026 · Journal Article · Animal feed science and technology

Astragalus polysaccharide and Agaricus Blazei polysaccharides improve growth performance, meat quality and health status of lambs via rescheduling the rumen microbiota

Since the banning of antibiotics, the use of green feed additives has become crucial for the healthy farming of mutton sheep. Astragalus polysaccharides (APS) and Agaricus Blazei polysaccharides (ABP) exhibit various functions such as antioxidation, immunomodulation, and meat quality improvement..

Immune supportEnergy & fatigueSkin & hydration

Snow Fungus · 2026 · Research Article · NPJ science of food

Beyond conventional drying: improving the quality of dried Tremella fuciformis via a heat-integrated pretreatment.

Hot-air drying (HAD) of Tremella fuciformis often results in poor rehydration capacity, yellowing, and long preparation times, which significantly reduce its industrial and consumer value. This study introduces a heat-integrated pretreatment (HIP) as a simple and viable strategy to improve the quality of dried T..

Oyster Mushroom · 2026 · Journal Article · Biometals: an international journal on the role of metal ions in biology, biochemistry, and medicine

Bioaccumulation and nutritional impact of fluoride in Pleurotus ostreatus and Pleurotus djamor with human health risk assessment.

Pleurotus species are nutritionally rich fungi, yet their potential to bioaccumulate environmental fluoride (F⁻) necessitates careful scientific evaluation further..

Reishi · 2026 · Journal Article · International journal of biological macromolecules

Biocatalytic transformation of Ganoderma lucidum by porcine pancreatic lipase in hydrophobic deep eutectic solvents.

Enzyme applications in industry are often limited by low stability, poor reusability and challenging recovery. This study presents a sustainable strategy for enhancing enzyme performance by immobilizing porcine pancreatic lipase (PPL) onto Ganoderma lucidum using a hydrophobic deep eutectic solvent (HDES) as a….

Oyster Mushroom · 2026 · Journal Article · Meat science

Cap and stipe extracts from Pleurotus ostreatus mushrooms reveal differences in enhancing the quality and stability of beef burgers during frozen storage

Previous studies have demonstrated the effectiveness of whole Pleurotus ostreatus (P. ostreatus) mushrooms and mushroom-derived ingredients as natural antioxidants in meat products.

Oyster Mushroom · 2026 · Journal Article · Meat science

Cap and stipe extracts from Pleurotus ostreatus mushrooms reveal differences in enhancing the quality and stability of beef burgers during frozen storage.

Previous studies have demonstrated the effectiveness of whole Pleurotus ostreatus (P. ostreatus) mushrooms and mushroom-derived ingredients as natural antioxidants in meat products.

Immune supportEnergy & fatigue

Enoki · 2026 · Research Article · Mycobiology

Comparative Evaluation of Disinfectants for Controlling Listeria monocytogenes on Flammulina Velutipes.

Flammulina velutipes is the most widely consumed edible mushroom in Korea, with a unique flavor and texture that support its popularity domestically and internationally. Korea produces approximately 26,000 tons of F..

Oyster Mushroom · 2026 · Research Article · Journal of fungi (Basel, Switzerland)

Comparative Mitogenomics Reveals Intron Dynamics and Mitochondrial Gene Expression Shifts in Domesticated and Wild Pleurotus ostreatus.

Mitochondrial genomes play a central role in fungal physiology and adaptation, yet their evolutionary dynamics during domestication remain poorly understood. Here, we performed a comparative mitogenomic and gene-expression analysis of three Pleurotus ostreatus dikaryotic strains differing in origin and degree of….

Lion's Mane · 2026 · Research Article · Frontiers in fungal biology

Comparative proteomic analysis reveals the effects of different light spectra on protein expression in Hericium erinaceus mycelium.

INTRODUCTION: Light represents a major environmental factor influencing the growth, developmental programming, and metabolic regulation of Hericium erinaceus. Different wavelengths differentially affect mycelial development, stress responses, and protein expression, highlighting the complexity of fungal….

Immune supportEnergy & fatigueGut & microbiome

Enoki · 2026 · Journal Article · Journal of fish biology

Comprehensive analysis of microbiome and transcriptome revealed the mechanisms of Flammulina velutipes stem-base enhance intestinal health in Gymnocypris eckloni.

Although Flammulina velutipes residues are increasingly used in fish feeds, their mode of action in the gut is poorly defined. Here, we show that feeding Gymnocypris eckloni diets supplemented with F..

Energy & fatigueSkin & hydration

Turkey Tail · 2026 · Research Article · ACS omega

Development and Application of a Hybrid Support of Laccase from Trametes versicolor with Zinc Oxide Nanoparticles for Textile Dye Degradation.

A hybrid support based on sodium alginate and green-synthesized ZnO nanoparticles was developed for the immobilization of laccase (Trametes versicolor) and applied to textile dye degradation..

Immune supportEnergy & fatigueGut & microbiome

Oyster Mushroom · 2026 · Research Article · Poultry science

Dietary evaluation of Pleurotus ostreatus spent mushroom substrate on productivity, nutrient digestibility, egg quality, antioxidant status, and ovarian cytoprotective responses in laying hens.

This study evaluated the dietary inclusion level effects of Pleurotus ostreatus spent mushroom substrate (SMS) on performance, nutrient digestibility, egg quality and oxidative stability in laying hens..

Energy & fatigueMetabolic healthGut & microbiome

Oyster Mushroom · 2026 · Research Article · Animal science journal = Nihon chikusan Gakkaiho

Effect of Supplemented Spent Mushroom Substrate (Pleurotus ostreatus) on Growth Performance, Nutrient Digestibility, Nitrogen Balance, and Blood Metabolites of Goats.

This study evaluated the effects of Pleurotus ostreatus spent mushroom substrate (SMS), supplemented with 4% urea and 18% molasses, as a partial replacement for Napier grass..

Snow Fungus · 2026 · Research Article · Foods (Basel, Switzerland)

Effect of Ultrafine Grinding on the Physicochemical Properties of Tremella fuciformis Powder and Its Aqueous Extracts.

The grinding of Tremella fuciformis is a critical step for its value-added processing and the efficient utilization of its functional components, significantly impacting product quality and process adaptability..

Immune supportEnergy & fatigueGut & microbiomeLiver support

Mesima · 2026 · Research Article · Poultry science

Effects of dietary Phellinus linteus polysaccharides supplementation on productive performance, egg quality, antioxidant status, immune function, cecal microbiota, jejunal morphology, and metabolism in laying hens under lipopolysaccharide challenge.

The effects of Phellinus linteus polysaccharides (PLP) on the immune responses of laying hens remain unclear. This study systematically investigated the impacts of PLP on productive performance, antioxidant status, immune response, cecal microbiota, short-chain fatty acids (SCFAs), jejunal morphology, and metabolism….

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Reishi · 2026 · Research Article · Animals: an open access journal from MDPI

Effects of Enzyme-Microbe Co-Fermented Ganoderma lucidum Spent Substrate on Growth Performance, Apparent Nutrient Digestibility, Organ Indices, and Gut Microbiota in Yellow-Feathered Broilers.

The effects of dietary supplementation of enzyme-microbe co-fermented Ganoderma lucidum spent substrate (EFGLS) on growth performance, apparent nutrient digestibility, organ indices, and cecal microbiota in yellow-feathered broilers are investigated..

Energy & fatigueLiver support

Reishi · 2026 · Research Article · Poultry science

Effects of hot water extract of Juncao-substrate Ganoderma lucidum residue on meat quality and antioxidant capacity of Liancheng white ducks.

The present study explored the effects of dietary supplementation with hot water extract of Juncao-substrate Ganoderma lucidum residue (HWE-JGLR) on growth performance, carcass traits, meat quality, and antioxidant capacity of Liancheng white ducks..

Immune supportEnergy & fatigueMetabolic health

Reishi · 2026 · Research Article · Microorganisms

Enhanced Exopolysaccharide Production in Bidirectional Liquid Fermentation of Ganoderma lucidum Using Clinacanthus nutans (Burm. f.) Lindau.

This study explored the enhancement of exopolysaccharide (EPS) production by Ganoderma lucidum through bidirectional liquid fermentation, employing Clinacanthus nutans (Burm. f.) Lindau leaves as a medicinal substrate.

Turkey Tail · 2026 · Research Article · International journal of molecular sciences

Enhanced Inhibition of Trametes versicolor by Structurally Modified Medicarpin: In Vitro Evaluation and In Silico Insights into Laccase Binding.

Medicarpin, a natural pterocarpan phytoalexin, contributes to tree defense against microbial decay, particularly from the aggressive white-rot fungus Trametes versicolor, an ASTM standard for wood durability testing..