MycoData

Here, the extraction of total flavonoids from Tremella fuciformis (TF) by aqueous two-phase extraction combined with ultrasound is presented. The extraction was optimized via a single-variable approach using the variables of mass fraction of ethanol and NaH2PO4, ultrasonication time, and TF sample amount..

High relevance

Shiitake · 2022 · Journal Article · Food Research International

Understanding the promotion of heat treatment on the flavor of Lentinula edodes using metabolomics integrated with transcriptomics

The transcriptome and metabolome analyses revealed the differentially expressed metabolites (DEMs) and genes (DEGs) in the dried Lentinula edodes' response to heat treatment..

Metabolic health

High relevance

Oyster Mushroom · 2022 · Research Article · Foods (Basel, Switzerland)

Use of Pleurotus ostreatus to Enhance the Oxidative Stability of Pork Patties during Storage and In Vitro Gastrointestinal Digestion.

Lipid and protein oxidation are the major causes of meat quality deterioration. Edible mushrooms have been proposed as a strategy to prevent quality deterioration during cold storage..

Immune supportGut & microbiome

High relevance

Lion's Mane · 2022 · Journal Article · Carbohydrate polymers

Value added immunoregulatory polysaccharides of Hericium erinaceus and their effect on the gut microbiota

Hericium erinaceus polysaccharides (HEPs) were isolated from the fruiting bodies of H. erinaceus with 53.36 % total carbohydrates and 32.56 % uronic acid.

Immune supportGut & microbiome

High relevance

Reishi · 2022 · Research Article · Journal of fungi (Basel, Switzerland)

Whole-Genome Sequencing and Transcriptome Analysis of Ganoderma lucidum Strain Yw-1-5 Provides New Insights into the Enhanced Effect of Tween80 on Exopolysaccharide Production.

Ganoderma lucidum is an important medicinal mushroom widely cultured in Asian countries. Exopolysaccharides are bioactive compounds of G.

Immune support

High relevance

Reishi · 2022 · Research Article · RSC advances

ZnO and Ag NP-decorated ZnO nanoflowers: green synthesis using Ganoderma lucidum aqueous extract and characterization.

Fungi produce and excrete various proteins, enzymes, polysaccharides, and secondary metabolites, which may be used as media for the "green" synthesis of metal and semiconductor nanoparticles (NPs)..

Immune supportEnergy & fatigue

High relevance

Snow Fungus · 2021 · Journal Article · International journal of food science & technology

A comparative study on the physio‐chemical properties, antioxidant and immuno‐stimulating activities of two national geographical indication products of Tremella fuciformis in China

Tremella fuciformis from Gutian in Fujian Province (TF‐GT) and Tongjiang in Sichuan Province (TF‐TJ) in China are two geographical indication (GI) products that are mainly differentiated and characterised by their cultivation methods. To better understand the qualities of the GI products of T..

Immune supportSkin & hydration

High relevance

Lion's Mane · 2021 · Journal Article · Journal of food biochemistry

A novel polysaccharide from Hericium erinaceus: Preparation, structural characteristics, thermal stabilities, and antioxidant activities in vitro

A novel polysaccharide fraction (HEP) from Hericium erinaceus was successively isolated and purified in the present study. We researched its structure and thermal stabilities, and further studied its antioxidant activities in vitro..

Immune supportEnergy & fatigueMetabolic health

High relevance

Shiitake · 2021 · Research Article · Oncology letters

A standardized extract of cultured Lentinula edodes mycelia downregulates cortactin in gemcitabine-resistant pancreatic cancer cells.

AHCC®, a standardized extract of cultured Lentinula edodes mycelia, enhances the therapeutic effects and reduces the adverse effects of chemotherapy. Our previous study reported that treatment with AHCC® downregulated the expression levels of tumor-associated proteins in the gemcitabine-resistant pancreatic cancer….

OncologySkin & hydration

High relevance

Oyster Mushroom · 2021 · Journal Article · International journal of biological macromolecules

A water-soluble selenium-enriched polysaccharide produced by Pleurotus ostreatus: Purification, characterization, antioxidant and antitumor activities in vitro.

The development and application of new selenium-enriched polysaccharides has become a critical topic in recent years. In this study, a natural selenium-enriched polysaccharide fraction (Se-POP-21) produced by Pleurotus ostreatus was purified, characterized, and investigated the antioxidant and antitumor activities in….

OncologyImmune supportMetabolic health

High relevance

Mesima · 2021 · Journal Article · Gene

Active ingredients and mechanisms of Phellinus linteus (grown on Rosa multiflora) for alleviation of Type 2 diabetes mellitus through network pharmacology.

Phellinus linteus (mushroom) grown on Rosa multiflora (PL@RM), exposed beneficial effect and safety on Type 2 diabetes mellitus (T2DM) from Korean folk remedies. However, its active chemical constituents and mechanism(s) against T2DM have not been confirmed..

Energy & fatigueMetabolic health

High relevance

Turkey Tail · 2021 · Journal Article · Food and Bioproducts Processing

Activity enhancement of Trametes versicolor aflatoxin B1-degrading enzyme (TV-AFB1D) by molecular docking and site-directed mutagenesis techniques

Aflatoxin B₁ (AFB₁) is highly carcinogenic and teratogenic as a secondary metabolite of Aspergillus flavus and Aspergillus parasiticus. Trametes versicolor aflatoxin B₁-degrading enzyme (TV-AFB₁D) has capability of AFB₁ degradation..

Energy & fatigue

High relevance

Reishi · 2021 · Research Article · ACS omega

Advancement of Microwave-Assisted Biosynthesis for Preparing Au Nanoparticles Using Ganoderma lucidum Extract and Evaluation of Their Catalytic Reduction of 4-Nitrophenol.

This study describes the biosynthesis of gold nanoparticles (AuNPs) using the extract of Ganoderma lucidum in the buffer zone of Bach Ma National Park, Vietnam, as a reducing and protecting agent using microwave-assisted synthesis..

Energy & fatigue

High relevance

Oyster Mushroom · 2021 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Alternating current electric field inhibits browning of Pleurotus ostreatus via inactivation of oxidative enzymes during postharvest storage

Oyster mushrooms (Pleurotus ostreatus, P. ostreatus) are rich in nutrients and have a pleasant flavour.

Energy & fatigue

High relevance

Oyster Mushroom · 2021 · Journal Article · Microbial cell factories

Alternative oxidase gene induced by nitric oxide is involved in the regulation of ROS and enhances the resistance of Pleurotus ostreatus to heat stress.

BACKGROUND: In China, during the cultivation process of Pleurotus ostreatus, the yield and quality of fruiting bodies are easily affected by high temperatures in summer..

Energy & fatigue

High relevance

Oyster Mushroom · 2021 · Journal Article · Environmental science and pollution research international

An assessment of Pleurotus ostreatus to remove sulfonamides, and its role as a biofilter based on its own spent mushroom substrate.

A double strategy based on the removal of sulfonamide antibiotics by Pleurotus ostreatus and adsorption on spent mushroom substrate was assessed to reclaim contaminated wastewater. P..

High relevance

Niu-Chang-Chih · 2021 · Journal Article · Journal of separation science

An efficient high-speed countercurrent chromatography method for preparative isolation of highly potent anti-cancer compound antroquinonol from Antrodia camphorata after experimental design optimized extraction.

To avoid irreversible stationary phase adsorption and tedious and time-consuming separation steps, high-speed countercurrent chromatography was employed for the preparative separation of anti-tumor compound antroquinonol from solid fermentation culture of Antrodia camphorata for the first time..

OncologyEnergy & fatigue

High relevance

Maitake · 2021 · Research Article · Pharmaceutics

Anti-Inflammatory and Immunomodulatory Effects of the Grifola frondosa Natural Compound o-Orsellinaldehyde on LPS-Challenged Murine Primary Glial Cells. Roles of NF-κβ and MAPK.

In response to foreign or endogenous stimuli, both microglia and astrocytes adopt an activated phenotype that promotes the release of pro-inflammatory mediators. This inflammatory mechanism, known as neuroinflammation, is essential in the defense against foreign invasion and in normal tissue repair; nevertheless, when….

Immune supportCognition & nerves

High relevance

Maitake · 2021 · Journal Article · Food & function

Anti-obesity effects of Grifola frondosa through the modulation of lipid metabolism via ceramide in mice fed a high-fat diet.

Obesity is characterized by massive fat deposition and is related to a series of metabolic complications, such as insulin resistance (IR) and steatohepatitis. Grifola frondosa (GF) is a basidiomycete fungus and a source of various nutritional ingredients related to human health..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Cordyceps · 2021 · Research Article · Food technology and biotechnology

Antioxidant and Cytotoxic Effects and Identification of Ophiocordyceps sinensis Bioactive Proteins Using Shotgun Proteomic Analysis.

RESEARCH BACKGROUND: Ophiocordyceps sinensis, a highly valued medicinal fungus, is close to extinction due to overexploitation. Successful cultivation of O.

OncologyImmune support

High relevance

Niu-Chang-Chih · 2021 · Journal Article · Food & function

Antrodin A from Antrodia camphorata modulates the gut microbiome and liver metabolome in mice exposed to acute alcohol intake.

This study aimed to investigate the protective effect of Antrodin A (AdA) from Antrodia camphorata (A. camphorata) mycelium on alcohol-induced gut microbiota and liver metabolomic disorders..

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Snow Fungus · 2021 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Application of curcumin-mediated antibacterial photodynamic technology for preservation of fresh Tremella Fuciformis

Tremella Fuciformis is an edible fungus with high water content and nutritional values. However, fresh T.

Gut & microbiome

High relevance

Zhu Ling · 2021 · Research Article · Frontiers in microbiology

Armillaria mellea Symbiosis Drives Metabolomic and Transcriptomic Changes in Polyporus umbellatus Sclerotia.

Sclerotia, the medicinal part of Polyporus umbellatus, play important roles in diuresis and renal protection, with steroids and polysaccharides as the main active ingredients. The sclerotia grow and develop only after symbiosis with Armillaria sp..

Immune supportEnergy & fatigueMetabolic health

High relevance

Chaga · 2021 · Journal Article · Natural product research

Aromatic compounds from the sclerotia of Inonotus obliquus.

Three new aromatic compounds (1a/1b, 2) including a pair of enantiomers (1a/1b), were isolated from Inonotus obliquus. The structures of the new compounds were elucidated by extensive spectroscopic analyses, and the absolute configurations of 1a and 1b were determined by electronic circular dichroism (ECD) calculated..

Oncology

High relevance

Wood Ear · 2021 · Journal Article · Journal of food science

Auricularia auricula-judae (Bull.) polysaccharides improve type 2 diabetes in HFD/STZ-induced mice by regulating the AKT/AMPK signaling pathways and the gut microbiota.

Auricularia auricula-judae is an edible fungus with high nutritional value due to abundant polysaccharides, and is acknowledged as traditional food and medicine in Asia. Polysaccharides from A.

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Turkey Tail · 2021 · Research Article · International journal of molecular sciences

Biodegradation of Chloroxylenol by Cunninghamella elegans IM 1785/21GP and Trametes versicolor IM 373: Insight into Ecotoxicity and Metabolic Pathways.

Chloroxylenol (PCMX) is applied as a preservative and disinfectant in personal care products, currently recommended for use to inactivate the SARS-CoV-2 virus. Its intensive application leads to the release of PCMX into the environment, which can have a harmful impact on aquatic and soil biotas..

Metabolic healthRespiratory

High relevance

Turkey Tail · 2021 · Research Article · 3 Biotech

Bioremediation of phenolic pollutant bisphenol A using optimized reverse micelles system of Trametes versicolor laccase in non-aqueous environment.

UNLABELLED: In recent times, there is increased public interest and indeed strong movement against the use of Bisphenol A (4,4'-(propane-2,2,-diphenol)) due to its endocrine disrupting properties. In the present study, biotransformation of Bisphenol A (BPA) was accomplished using Trametes versicolor laccase (E.C..

Skin & hydration

High relevance

Shiitake · 2021 · Journal Article · Acta chimica Slovenica

Biosorption of Hexavalent Chromium Metal Ions by Lentinula Edodes Biomass: Kinetic, Isothermal, and Thermodynamic Parameters.

Lentinula edodes was investigated as a biosorbent for hexavalent chromium biosorption in this study. To examine the optimum conditions of biosorption, the pH of the hexavalent chromium solution, biosorbent dosage, temperature, contact time, and initial hexavalent chromium concentration were identified..

High relevance

Enoki · 2021 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

Biosynthesis of pleasant aroma by enokitake (Flammulina velutipes) with a potential use in a novel tea drink

Western consumers prefer tea products with little or no green flavor. Accordingly, edible basidiomycetes have been addressed as an innovative tool to naturally aromatize tea infusion to mask or reduce green flavor..

High relevance

Chaga · 2021 · Research Article · Journal of microbiology and biotechnology

Carbon Source Affects Synthesis, Structures, and Activities of Mycelial Polysaccharides from Medicinal Fungus Inonotus obliquus.

The effects of various carbon sources on mycelial growth and polysaccharide synthesis of the medicinal fungus Inonotus obliquus in liquid fermentation were investigated..

OncologyImmune supportMetabolic health

High relevance

Lion's Mane · 2021 · Research Article · Frontiers in bioengineering and biotechnology

Characterization and Heterologous Expression of UDP-Glucose 4-Epimerase From a Hericium erinaceus Mutant with High Polysaccharide Production.

Hericium erinaceus is an important medicinal fungus in traditional Chinese medicine because of its polysaccharides and other natural products. Compared terpenoids and polyketides, the analysis of synthetic pathway of polysaccharides is more difficult because of the many genes involved in central metabolism..

Immune supportMetabolic health

High relevance

Snow Fungus · 2021 · Journal Article · Antonie van Leeuwenhoek

Characterization of a G protein α subunit encoded gene from the dimorphic fungus-Tremella fuciformis.

Tremella fuciformis is a dimorphic fungus which can undertake the reversible transition between yeast and pseudohypha forms. G protein α subunit (Gα) carries different signals to regulate a variety of biological processes in eukaryotes, including fungal dimorphism..

High relevance

Snow Fungus · 2021 · Journal Article · International Journal of Biological Macromolecules

Characterization of chitin-glucan complex from Tremella fuciformis fermentation residue and evaluation of its antibacterial performance

Submerged fermentation of fungi is an efficient way to obtain extracellular polysaccharides, however, in this process, excess discarded biomass is produced. In this study, Tremella fuciformis mycelia were reused as the raw material to isolate a novel fungal chitin-glucan complex (CGC-TFM) using alkaline extraction..

Immune supportEnergy & fatigueMetabolic health

High relevance

Snow Fungus · 2021 · Journal Article · International journal of biological macromolecules

Characterization of chitin-glucan complex from Tremella fuciformis fermentation residue and evaluation of its antibacterial performance.

Immune supportEnergy & fatigueMetabolic health

High relevance

Enoki · 2021 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Characterization of soy protein isolate/Flammulina velutipes polysaccharide hydrogel and its immunostimulatory effects on RAW264.7 cells.

Soy protein isolate (SPI) is a nutritional commercial product, while the poor solubility and gelling restricts its applications for functional foods. To surmount the challenge presented by this poor solubility, the gelling polysaccharide shows potential in ameliorating SPI..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Enoki · 2021 · Research Article · Molecules (Basel, Switzerland)

Characterization, Antioxidant and Anti-Inflammation Capacities of Fermented Flammulina velutipes Polyphenols.

This work investigated the preparation, characterization, antioxidant, and anti-inflammation capacities of Flammulina velutipes polyphenols (FVP) and fermented FVP (FFVP). The results revealed that the new syringic acid, accounting for 22.22%, was obtained after fermentation (FFVP)..

Immune support

High relevance

Niu-Chang-Chih · 2021 · Journal Article · Journal of Asian natural products research

Chemical constituents from the dish-cultured Antrodia camphorata and their cytotoxic activities.

One new meroterpenoid, antroquinonol Y (1), a new ergostane-type sterol, antcamphin Y (2), and a new ergostane-type triterpenoid, antcamphin Z (3), together with 10 known ones (4-13), were isolated from the dish-cultured fungus Antrodia camphorata..

Oncology

High relevance

Niu-Chang-Chih · 2021 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Coenzyme Q0, a novel quinone derivative of Antrodia camphorata, induces ROS-mediated cytotoxic autophagy and apoptosis against human glioblastoma cells in vitro and in vivo.

Coenzyme Q0 (CoQ0, 2,3-dimethoxy-5-methyl-1,4-benzoquinone) derived from Antrodia camphorata exerts anticancer activities against breast, melanoma, and ovarian carcinoma. Glioblastoma multiforme is a common tumor affecting the central nervous system..

OncologyGut & microbiome

High relevance

Cordyceps · 2021 · Research Article · PeerJ

Comparative analysis of fatty acid metabolism based on transcriptome sequencing of wild and cultivated Ophiocordyceps sinensis.

BACKGROUND: Ophiocordyceps sinensis is a species endemic to the alpine and high-altitude areas of the Qinghai-Tibet plateau. Although O.

High relevance

Oyster Mushroom · 2021 · Journal Article · Applied microbiology and biotechnology

Comparative transcriptional analyses of Pleurotus ostreatus mutants on beech wood and rice straw shed light on substrate-biased gene regulation.

Distinct wood degraders occupying their preferred habitats have biased enzyme repertoires that are well fitted to their colonized substrates. Pleurotus ostreatus, commonly found on wood, has evolved its own enzyme-producing traits.

Gut & microbiome

High relevance

Turkey Tail · 2021 · Journal Article · Journal of environmental management

Comparison between two reactors using Trametes versicolor for agricultural wastewater treatment under non-sterile condition in sequencing batch mode.

Agricultural wastewater is a major source of herbicides, which pose environmental and health concerns owing to their substantial use and poor elimination rate in conventional wastewater treatment plants..

High relevance

Lion's Mane · 2021 · Journal Article · Carbohydrate polymers

Construction of hydrogels based on the homogeneous carboxymethylated chitin from Hericium erinaceus residue: Role of carboxymethylation degree.

Carboxymethyl chitin hydrogels with different degree of substitution (DS) were prepared by the homogeneous carboxymethylation of chitin extracted from Hericium erinaceus residue. The effect of DS on gel structure and property were studied..

Energy & fatigue

High relevance

Shiitake · 2021 · Journal Article · Journal of food biochemistry

Cytotoxicity, metabolic enzyme inhibitory, and anti-inflammatory effect of Lentinula edodes fermented using probiotic lactobacteria.

We found that the fermented Lentinula edodes (FLE) products exhibited various differences in terms of proximate composition, free sugar, and amino acid. In particular, there were higher levels of ergosterol, and ergothioneine in FLE-Pediococcus pentosaceus (PP) and -Lactobacillus acidophilus (LA) than in the L..

OncologyImmune supportMetabolic healthGut & microbiome

High relevance

Shiitake · 2021 · Research Article · Frontiers in microbiology

De novo Sequencing and Comparative Transcriptome Analyses Provide First Insights Into Polysaccharide Biosynthesis During Fruiting Body Development of Lentinula edodes.

Polysaccharides separated from Lentinula edodes are well known for their medicinal properties. However, the precise molecular mechanisms of polysaccharide biosynthesis in L.

Immune supportMetabolic health

High relevance

Turkey Tail · 2021 · Research Article · Saudi journal of biological sciences

Deciphering the CNS anti-depressant, antioxidant and cytotoxic profiling of methanol and aqueous extracts of Trametes versicolor and molecular interactions of its phenolic compounds.

The present study sought to evaluate the central nervous system (CNS) depressant, antioxidant, and cytotoxicity activity of methanol and aqueous extract of Trametes versicolor (METV and AETV)..

OncologyCognition & nervesEnergy & fatigue

High relevance

Cordyceps · 2021 · Journal Article · International journal of medicinal mushrooms

Deep Sequencing, Nested PCR, and Denaturing Gradient Gel Electrophoresis Reveal a Wider Distribution of Chinese Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycetes), in Native Soil Types.

Ophiocordyceps sinensis appears as stroma emerging from underground sclerotium enclosed by the skeleton of Thitarodes moth larvae. However, the actual distribution of the fungus in soil still remains unclarified.

High relevance

Shiitake · 2021 · Journal Article · Food chemistry

Determining the amount of potentially bioavailable phenolic compounds and bioelements in edible mushroom mycelia of Agaricus bisporus, Cantharellus cibarius, and Lentinula edodes.

Release of bioelements and phenolic compounds from edible mushrooms (Agaricus bisporus, Cantharellus cibarius, and Lentinula edodes) enriched with zinc, selenium, l-phenylalanine, alone and as a mixture was examined using a simulated human gastrointestinal digestion method..

Gut & microbiome

High relevance

Oyster Mushroom · 2021 · Research Article · Biotechnology for biofuels

Development of a consortium-based microbial agent beneficial to composting of distilled grain waste for Pleurotus ostreatus cultivation.

BACKGROUND: Pleurotus ostreatus is an edible mushroom popularly cultivated worldwide. Distilled grain waste (DGW) is a potential substrate for P.

Gut & microbiome

High relevance

Oyster Mushroom · 2021 · Research Article · Journal of fungi (Basel, Switzerland)

Differential Induction Pattern Towards Classically Activated Macrophages in Response to an Immunomodulatory Extract from Pleurotus ostreatus Mycelium.

Pleurotus ostreatus mushroom preparations have been investigated because of their ability to modulate the immune function. However, there is still no consensus regarding the activation and polarizing effect on macrophages by Pleurotus-derived bioproducts..

OncologyImmune support

High relevance

Shiitake · 2021 · Research Article · Mycobiology

Discovery and Functional Study of a Novel Genomic Locus Homologous to Bα-Mating-Type Sublocus of Lentinula edodes.

The interaction of mating pheromone and pheromone receptor from the B mating-type locus is the first step in the activation of the mushroom mating signal transduction pathway..