MycoData

Immune supportMetabolic healthLiver support

King Oyster · 2018 · Research Support, Non U.S. Gov'T · Scientific reports

The characteristic, antioxidative and multiple organ protective of acidic-extractable mycelium polysaccharides by Pleurotus eryngii var. tuoliensis on high-fat emulsion induced-hypertriglyceridemic mice.

The antioxidant and multiple organ protection effects of acid- extracted mycelia polysaccharides (Ac-MPS) from Pleurotus eryngii var. tuoliensis on HFE-induced hypertriglyceridemic mice were investigated..

Reishi · 2018 · Evaluation Study · International journal of medicinal mushrooms

Ultra-Low Freezing to Preserve the Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes).

Ganoderma lucidum (Curtis) P. Karst., commonly used in traditional Chinese medicine, is characterized by strong genetic and phenotypic variability that reflects its active components..

Cordyceps · 2018 · Research Support, Non U.S. Gov'T · Scientific reports

Uncovering global metabolic response to cordycepin production in Cordyceps militaris through transcriptome and genome-scale network-driven analysis.

The cellular metabolic adaptations of Cordyceps militaris have been progressively studied. In particular, the cordycepin pathway is of interest in medicinal applications..

Metabolic health

Cordyceps · 2017 · Comparative Study · Scientific reports

Comparative mitochondrial genomics toward exploring molecular markers in the medicinal fungus Cordyceps militaris.

Cordyceps militaris is a fungus used for developing health food, but knowledge about its intraspecific differentiation is limited due to lack of efficient markers. Herein, we assembled the mitochondrial genomes of eight C..

Shiitake · 2017 · Brief Report · Mycobiology

Development and Molecular Characterization of Novel Polymorphic Genomic DNA SSR Markers in Lentinula edodes.

Sixteen genomic DNA simple sequence repeat (SSR) markers of Lentinula edodes were developed from 205 SSR motifs present in 46.1-Mb long L. edodes genome sequences.

Cordyceps · 2017 · Research Support, Non U.S. Gov'T · Advances in experimental medicine and biology

Fermented Asterina pectinifera with Cordyceps militaris Mycelia Induced Apoptosis in B16F10 Melanoma Cells.

This prime objective of this study was to explore the anti-cancer activity of fermented Asterina pectinifera with Cordyceps militaris mycelia (FACM) in B16F10 murine melanoma cells. The effect of FACM on cell viability was assessed using MTT assay.

Oncology

Lion's Mane · 2017 · Research Support, Non U.S. Gov'T · Scientific reports

Genomic and transcriptomic analyses reveal differential regulation of diverse terpenoid and polyketides secondary metabolites in Hericium erinaceus.

The lion's mane mushroom Hericium erinaceus is a famous traditional medicinal fungus credited with anti-dementia activity and a producer of cyathane diterpenoid natural products (erinacines) useful against nervous system diseases..

Cognition & nerves

Cordyceps · 2017 · Comparative Study · PloS one

Insight into cordycepin biosynthesis of Cordyceps militaris: Comparison between a liquid surface culture and a submerged culture through transcriptomic analysis.

Cordyceps militaris produces cordycepin, which is known to be a bioactive compound. Currently, cordycepin hyperproduction of C.

Immune supportCognition & nerves

Maitake · 2017 · Comparative Study · Molecular nutrition & food research

Oral administration of Grifola frondosa polysaccharides improves memory impairment in aged rats via antioxidant action.

SCOPE: Grifola frondosa is an edible/medicinal mushroom with great nutritional value and bioactivity. The present study was performed to evaluate the beneficial effect of polysaccharides isolated from Grifola frondosa on memory impairment in aged rats..

Turkey Tail · 2017 · Research Support, Non U.S. Gov'T · International journal of environmental research and public health

Preparation and Optimisation of Cross-Linked Enzyme Aggregates Using Native Isolate White Rot Fungi Trametes versicolor and Fomes fomentarius for the Decolourisation of Synthetic Dyes.

The key to obtaining an optimum performance of an enzyme is often a question of devising a suitable enzyme and optimisation of conditions for its immobilization. In this study, laccases from the native isolates of white rot fungi Fomes fomentarius and/or Trametes versicolor, obtained from Czech forests, were used..

Cordyceps · 2017 · Research Support, Non U.S. Gov'T · Scientific reports

Soya-cerebroside, an extract of Cordyceps militaris, suppresses monocyte migration and prevents cartilage degradation in inflammatory animal models.

Pathophysiological events that modulate the progression of structural changes in osteoarthritis (OA) include the secretion of inflammatory molecules, such as proinflammatory cytokines..

Immune supportLiver support

Cordyceps · 2017 · Research Support, Non U.S. Gov'T · Scientific reports

Systems Pharmacology-based strategy to screen new adjuvant for hepatitis B vaccine from Traditional Chinese Medicine Ophiocordyceps sinensis.

Adjuvants are common component for many vaccines but there are still few licensed for human use due to low efficiency or side effects. The present work adopted Systems Pharmacology analysis as a new strategy to screen adjuvants from traditional Chinese medicine..

Cordyceps · 2017 · Research Support, Non U.S. Gov'T · Scientific reports

The caterpillar fungus, Ophiocordyceps sinensis, genome provides insights into highland adaptation of fungal pathogenicity.

To understand the potential genetic basis of highland adaptation of fungal pathogenicity, we present here the ~116 Mb de novo assembled high-quality genome of Ophiocordyceps sinensis endemic to the Qinghai-Tibetan Plateau. Compared with other plain-dwelling fungi, we find about 3.4-fold inflation of the O..

Turkey Tail · 2016 · Research Support, Non U.S. Gov'T · Biotechnology letters

A novel ethanol-tolerant laccase, Tvlac, from Trametes versicolor.

OBJECTIVES: To produce and characterize novel laccases with ethanol tolerance from Trametes versicolor using agriculture by-products as energy source. RESULTS: Trametes versicolor 1017 produces two laccase isoenzymes with a total activity of 10 U ml(-1) within 8 days when using wheat bran and peanut powder as energy….

Cordyceps · 2016 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Anti-inflammatory Cerebrosides from Cultivated Cordyceps militaris.

Cordyceps militaris (bei-chong-chaw, northern worm grass) is a precious and edible entomopathogenic fungus, which is widely used in traditional Chinese medicine (TCM) as a general booster for the nervous system, metabolism, and immunity. Saccharides, nucleosides, mannitol, and sterols were isolated from this fungus..

Immune supportEnergy & fatigue

King Oyster · 2016 · Research Support, Non U.S. Gov'T · Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

Biodegradation of toxic chemicals by Pleurotus eryngii in submerged fermentation and solid-state fermentation.

BACKGROUND/PURPOSE: The toxic chemicals bisphenol A (BPA), bisphenol F (BPF), nonylphenol (NP), and tetrabromobisphenol A (TBBPA) are endocrine-disrupting chemicals that have consequently drawn much concern regarding their effect on the environment..

OncologyImmune supportMetabolic healthLiver support

King Oyster · 2016 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Chemical characterization of Pleurotus eryngii polysaccharide and its tumor-inhibitory effects against human hepatoblastoma HepG-2 cells.

This study was designed to investigate the chemical characterization and antitumor effects of Pleurotus eryngii polysaccharides (PEP). The crude PEP was fractionated into two fractions, namely PEP-1 and PEP-2..

OncologyImmune supportMetabolic health

Cordyceps · 2016 · Research Support, Non U.S. Gov'T · Food & function

Cordyceps militaris fruit body extract ameliorates membranous glomerulonephritis by attenuating oxidative stress and renal inflammation via the NF-κB pathway.

Membranous glomerulonephritis (MGN) is a common pathogenesis of nephritic syndrome in adult patients. Nuclear factor kappa B (NF-κB) serves as the main transcription factor for the inflammatory response mediated nephropathy..

Cordyceps · 2016 · Research Support, Non U.S. Gov'T · Gene

De novo transcriptome analysis of Thitarodes jiachaensis before and after infection by the caterpillar fungus, Ophiocordyceps sinensis.

Thitarodes jiachaensis is a host species of the pathogenic caterpillar fungus Ophiocordyceps sinensis, which is a fungus with broad medical effects and great economic value. Curated genomic information on Thitarodes is still limited, and the interaction between host Thitarodes larvae and O..

Cognition & nerves

King Oyster · 2016 · Research Support, Non U.S. Gov'T · Journal of food science

Effect of Pleurotus eryngii Mushroom β-Glucan on Quality Characteristics of Common Wheat Pasta.

The objective of this study was to evaluate the effect of β-glucan-rich fractions (BGRFs) from Pleurotus eryngii mushroom powder on the quality, textural properties, and sensory evaluation of common wheat pasta..

Immune supportLiver supportSkin & hydration

Shiitake · 2016 · Research Support, Non U.S. Gov'T · Journal of medicinal food

Extracts from Lentinula edodes (Shiitake) Edible Mushrooms Enriched with Vitamin D Exert an Anti-Inflammatory Hepatoprotective Effect.

Vitamin D has been known for its anti-inflammatory properties. Extracts derived from Lentinula edodes (Shiitake) edible mushroom exert an anti-inflammatory effect..

Shiitake · 2016 · Comparative Study · Revista Argentina de microbiologia

Hydrolytic enzyme activities in shiitake mushroom (Lentinula edodes) strains cultivated on coffee pulp.

Hydrolytic enzyme production (cellulases, laminarinases and xylanases) was studied in cultures of Lentinula edodes on sterilized coffee pulp. Samples of substrate colonized by mycelia were taken after 7, 14, 21, 28 and 35 days of incubation at 25°C (W1 to W5) and during the fruiting period at different stages:….

Gut & microbiome

Shiitake · 2016 · Research Support, Non U.S. Gov'T · Revista de biologia tropical

Lentinula edodes based GIS mapping, biometabolites and antiinflamatory activity of wild edible mushrooms from tropical ‘sacred grove’ forests of Meghalaya, India.

The biodiversity rich state of Meghalaya, India located in the realms of mega-biodiversity hotspots, is home to numerous species of wild edible macrofungi that are used extensively by the mycophillic ethnic population, as a part of their traditional cuisine and medicine systems..

King Oyster · 2016 · Research Support, Non U.S. Gov'T · Current microbiology

Pantoea pleuroti sp. nov., Isolated from the Fruiting Bodies of Pleurotus eryngii.

Four Gram-negative-staining, facultatively anaerobic bacterial isolates were obtained from the fruiting bodies of the edible mushroom Pleurotus eryngii showing symptoms of bacterial blight disease in Beijing, China. Nearly complete 16S rRNA gene sequencing placed these isolates in the genus Pantoea..

Immune supportLiver support

King Oyster · 2016 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Pleurotus eryngii Polysaccharide Promotes Pluripotent Reprogramming via Facilitating Epigenetic Modification.

Pleurotus eryngii is a medicinal/edible mushroom with great nutritional value and bioactivity. Its polysaccharide has recently been developed into an effective gene vector via cationic modification.

Shiitake · 2016 · Research Support, Non U.S. Gov'T · Scientific reports

Population genomic analysis uncovers environmental stress-driven selection and adaptation of Lentinula edodes population in China.

The elucidation of genome-wide variations could help reveal aspects of divergence, domestication, and adaptation of edible mushrooms. Here, we resequenced the whole genomes of 39 wild and 21 cultivated strains of Chinese Lentinula edodes, the shiitake mushroom..

King Oyster · 2016 · Research Support, Non U.S. Gov'T · Preparative biochemistry & biotechnology

Production of versatile peroxidase from Pleurotus eryngii by solid-state fermentation using agricultural residues and evaluation of its catalytic properties.

Interest in production of ligninolytic enzymes has been growing over recent years for their use in various applications such as recalcitrant pollutants bioremediation; specifically, versatile peroxidase (VP) presents a great potential due to its catalytic versatility..

Metabolic health

King Oyster · 2016 · Research Support, Non U.S. Gov'T · Electrophoresis

Secretome analysis of Pleurotus eryngii reveals enzymatic composition for ramie stalk degradation.

Pleurotus eryngii (P. eryngii) can secrete large amount of hydrolytic and oxidative enzymes to degrade lignocellulosic biomass.

King Oyster · 2016 · Research Support, Non U.S. Gov'T · Scientific reports

The famous cultivated mushroom Bailinggu is a separate species of the Pleurotus eryngii species complex.

The mushroom of the genus Pleurotus in western China, called Bailinggu, is a precious edible fungus with high economic value. However, its taxonomical position is unclear.

Cordyceps · 2016 · Research Support, Non U.S. Gov'T · Applied microbiology and biotechnology

The intronic minisatellite OsMin1 within a serine protease gene in the Chinese caterpillar fungus Ophiocordyceps sinensis.

Repetitive DNA sequences make up a significant portion of all genomes and may occur in intergenic, regulatory, coding, or even intronic regions. Partial sequences of a serine protease gene csp1 was previously used as a population genetic marker of the Chinese caterpillar fungus Ophiocordyceps sinensis, but its first….

Metabolic healthLiver support

King Oyster · 2016 · Research Support, Non U.S. Gov'T · Genetics and molecular research: GMR

Therapeutic effect of Pleurotus eryngii cellulose on experimental fatty liver in rats.

The aim of this study was to explore the therapeutic effect of Pleurotus eryngii cellulose on experimental fatty liver in rats. Rats were fed high-fat fodder to establish a rat fatty liver model, and were then fed different concentrations of Pleurotus eryngii cellulose for six weeks..

Wood Ear · 2016 · Research Support, Non U.S. Gov'T · Bioresource technology

Torrefaction of cultivation residue of Auricularia auricula-judae to obtain biochar with enhanced fuel properties.

Auricularia auricula-judae, commonly known as the wood ear, is a species of edible Auriculariales fungus. Torrefactions of cultivation residues of A.

King Oyster · 2016 · Research Support, Non U.S. Gov'T · Food chemistry

Toughening and its association with the postharvest quality of king oyster mushroom (Pleurotus eryngii) stored at low temperature.

Toughening-induced textural decay easily occurs in stored mushrooms. The objective of this study was to investigate the textural alteration caused by toughening in relation to other quality attributes of king oyster mushroom (Pleurotus eryngii)..

Cordyceps · 2016 · Research Support, Non U.S. Gov'T · Fungal biology

Transcriptome analysis of Ophiocordyceps sinensis before and after infection of Thitarodes larvae.

Ophiocordyceps sinensis, also referred to as the Chinese caterpillar fungus, is a rare entomopathogenic fungus found in the Qinghai-Tibetan Plateau that is used as a traditional Chinese medicine. O.

Shiitake · 2016 · Research Support, Non U.S. Gov'T · Journal of biotechnology

Whole genome de novo sequencing and genome annotation of the world popular cultivated edible mushroom, Lentinula edodes.

Lentinula edodes, the popular shiitake mushroom, is one of the most important cultivated edible mushrooms. It is used as a food and for medicinal purposes.

Cordyceps · 2015 · Journal Article · Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]

[Assessment of Antitumor Effect of Submerged Culture of Ophiocordyceps sinensis and Cordyceps militaris].

Ophiocordyceps sinensis and Cordyceps militaris metabolites showed a high potential in the treatment of tumors as well as some other diseases. Antitumor properties of O.

Oncology

Cordyceps · 2015 · Journal Article · Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

[Effects of Germanium Concentrations on Germanium Accumulation and Biotransformation of Polysaccarified Germanium in Cordyceps militaris].

OBJECTIVE: To study the effects of Germanium (Ge) concentration on Ge accumulation and biotransformation of polysaccarified Ge (PG) in Cordyceps militaris. METHODS: Solid and liquid culture were used in this study..

Niu-Chang-Chih · 2015 · Journal Article · Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

[Study on Chemical Constituents of Fermented Antrodia camphorata Powder].

OBJECTIVE: To study the chemical constituents of fermented Antrodia camphorata powder. METHODS: 15 compounds were isolated from Antrodia camphorata by Silica gel column chromatography, ODS column chromatography, gel column chromatography, preparative liquid phase chromatography separation technique, as well as….

OncologyImmune supportMetabolic health

Cordyceps · 2015 · Research Article · Pharmacognosy magazine

A direct protein kinase B-targeted anti-inflammatory activity of cordycepin from artificially cultured fruit body of Cordyceps militaris.

BACKGROUND: Cordyceps militaris is one of well-known medicinal mushrooms with anti-inflammatory, anti-cancer, anti-diabetic, and anti-obesity activities. OBJECTIVE: The objective of the following study is to isolate chemical components from the ethanol extract (Cm-EE) from Cordyceps militaris and to evaluate their….

Cordyceps · 2015 · Journal Article · Innovative Food Science and Emerging Technologies

Antioxidant activity and DNA damage protection of mung beans processed by solid state fermentation with Cordyceps militaris SN-18

In this study, solid state fermentation of mung beans by Cordyceps militaris SN-18 (C. militaris-fermented mung beans, CFMB) was performed.

OncologyImmune supportLiver supportRespiratory

King Oyster · 2015 · Journal Article · Journal of food biochemistry

Antitumor and Immunomodulatory Activity of Pleurotus eryngii Extract

Pleurotus eryngii (P. eryngii), also known as the king oyster mushroom, contains many bioactive substances, including polysaccharides, lipids, peptides, sterols and triterpenoids.

Immune supportSkin & hydration

Niu-Chang-Chih · 2015 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Application of Antrodia camphorata Promotes Rat's Wound Healing In Vivo and Facilitates Fibroblast Cell Proliferation In Vitro.

Antrodia camphorata is a parasitic fungus from Taiwan, it has been documented to possess a variety of pharmacological and biological activities. The present study was undertaken to evaluate the potential of Antrodia camphorata ethanol extract to accelerate the rate of wound healing closure and histology of wound area….

Cognition & nervesMetabolic healthGut & microbiome

Almond Mushroom · 2015 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Aqueous Extract of Agaricus blazei Murrill Prevents Age-Related Changes in the Myenteric Plexus of the Jejunum in Rats.

This study evaluated the effects of the supplementation with aqueous extract of Agaricus blazei Murrill (ABM) on biometric and blood parameters and quantitative morphology of the myenteric plexus and jejunal wall in aging Wistar rats..

King Oyster · 2015 · Journal Article · Cellular and molecular biology (Noisy-le-Grand, France)

Capacity of a newly isolated fungus Pleurotus eryngii from Tunceli, Ovacik for chemical oxygen demand reduction and biodecolorization of Azo-Dye Congo Red.

Biodecolorization of Congo red dye in both agar—plate and agitated liquid culture mediums by newly isolated white rot fungus Pleurotus eryngii has been studied. This fungus isolated from Tunceli—Ovacik province of Turkey..

King Oyster · 2015 · Journal Article · European journal of plant pathology

Characterization and chemical control of soft rot disease caused by Pantoea sp. strain PPE7 in Pleurotus eryngii mushroom crops

The bacterial pathogen Pantoea sp. strain PPE7 causes severe soft rot disease in the king oyster mushroom, Pleurotus eryngii.

Mesima · 2015 · Research Article · Biotechnology, biotechnological equipment

De novo transcriptome analysis of a medicinal fungi Phellinus linteus and identification of SSR markers.

The aim of this study was to facilitate gene discovery for functional genome studies and to identify simple sequence repeat (SSR) markers for molecular-assisted selection in Phellinus linteus. The transcriptome of Phellinus linteus was sequenced using а high-throughput RNA sequencing system - the Illumina Hiseq 2000..

King Oyster · 2015 · Journal Article · International journal of food science & technology

Effects of different carbon sources and C/N values on nonvolatile taste components of Pleurotus eryngii

Pleurotus eryngii, the second largest industrial cultivation mushroom in China, is usually cultivated on substrates mainly consisting of sawdust and corncob. In this study, experiments were performed to determine the effects of different carbon sources and C/N values on nonvolatile taste components of P.

King Oyster · 2015 · Journal Article · Journal of dairy science

Effects of Pleurotus eryngii polysaccharides on bacterial growth, texture properties, proteolytic capacity, and angiotensin-I-converting enzyme-inhibitory activities of fermented milk.

Pleurotus eryngii is one of the most favored oyster mushrooms and contains various beneficial bioactive compounds. Polysaccharide extracted from P.