MycoData

Cordyceps · 2019 · Journal Article · Archives of microbiology

Genome-wide analysis of DNA methylation in subcultured Cordyceps militaris.

The entomopathogenic mushroom Cordyceps militaris is a storehouse of various medicinal compounds and pharmacological effects. However, the high frequency of strain degeneration during subculture and preservation severely limits the large-scale production of C.

Immune supportEnergy & fatigueMetabolic health

Cordyceps · 2019 · Research Article · Veterinary world

Growth performance and hematological changes in growing pigs treated with Cordyceps militaris spent mushroom substrate.

BACKGROUND AND AIM: This study was aimed to compare the efficacy of dietary Cordyceps militaris spent mushroom substrate (CMS) on growth performance, immunity, metabolic profiles, and antioxidant capacity in growing pigs..

OncologyImmune supportCognition & nervesMetabolic health

Lion's Mane · 2019 · Journal Article · Journal of medicinal food

Hericium erinaceus Mycelium and Its Isolated Compound, Erinacine A, Ameliorate High-Fat High-Sucrose Diet-Induced Metabolic Dysfunction and Spatial Learning Deficits in Aging Mice.

Aging and lifestyle factors, including high-sugar and high-fat diets, promote a systemic metabolic imbalance that promotes neurodegeneration. Hericium erinaceus has long been used in traditional Chinese medicine..

Lion's Mane · 2019 · Journal Article · Food Hydrocolloids

Hericium Erinaceus β-glucan modulates in vitro wheat starch digestibility

The mechanism of Hericium Erinaceus β-glucan inhibiting starch digestion has been seldom studied. In this study, the mechanism of inhibited starch digestion was explored in the context of interaction between β-glucans of different molecular weights (Mw) and starch..

Immune supportMetabolic healthGut & microbiomeLiver support

Maitake · 2019 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Hypoglycemic activity and gut microbiota regulation of a novel polysaccharide from Grifola frondosa in type 2 diabetic mice.

GFP-N, a novel heteropolysaccharide with a molecular weight of 1.26 × 107 Da, was isolated from maitake mushroom and purified by anion-exchange chromatography on a DEAE cellulose-52 column and gel-filtration chromatography on a Sephadex G-100 column..

Yellow Morel · 2019 · Journal Article · Journal of food science

Improvement of Biological Activity of Morchella esculenta Protein Hydrolysate by Microwave-Assisted Selenization.

Morchella esculenta protein hydrolysate (MPH) from a valued medicinal and edible fungus M. esculenta (L.) is an excellent material for functional food development.

Shiitake · 2019 · Journal Article · Food & function

In vitro and in vivo testing of the hypocholesterolemic activity of ergosterol- and β-glucan-enriched extracts obtained from shiitake mushrooms (Lentinula edodes).

Herein, a supercritical extraction plant (with a 6 L extraction cell) was successfully used to obtain ergosterol-enriched extracts from Lentinula edodes under the following conditions: a temperature of 40 °C, pressure of 225 bar, reaction time of 1-5 h, and the flow rate of 20 L h-1 for recirculated CO2..

OncologyImmune supportMetabolic health

Shiitake · 2019 · Journal Article · Carbohydrate polymers

Isolation and comparison of α- and β-D-glucans from shiitake mushrooms (Lentinula edodes) with different biological activities

A polysaccharide-enriched extract obtained from Lentinula edodes was submitted to several purification steps to separate three different D-glucans with β-(1→6), β-(1→3),(1→6) and α-(1→3) linkages, being characterized through GC–MS, FT-IR, NMR, SEC and colorimetric/fluorimetric determinations..

Metabolic healthSkin & hydration

Cordyceps · 2019 · Journal Article · Journal of microbiology (Seoul, Korea)

Metabolomic profiling reveals enrichment of cordycepin in senescence process of Cordyceps militaris fruit bodies.

Cordyceps militaris is a species of Cordyceps that is classified in the Cordycipitaceae family and is well known in East Asia as a traditional medicinal mushroom. Its artificial fruit body has been widely cultivated for commercial use in cosmetics, functional food, and medicine..

Immune supportMetabolic healthGut & microbiome

Snow Fungus · 2019 · Journal Article · International journal of biological macromolecules

Nanostructures assembly and the property of polysaccharide extracted from Tremella Fuciformis fruiting body.

Polysaccharides from fungi are good free radical scavengers. However, there are no enzymes digesting these polysaccharides in the human body, which limits the use of fungal polysaccharides..

Maitake · 2019 · Journal Article · International journal of biological macromolecules

Preparation of a novel Grifola frondosa polysaccharide-chromium (III) complex and its hypoglycemic and hypolipidemic activities in high fat diet and streptozotocin-induced diabetic mice.

Polysaccharide from Grifola frondosa is one of the best metal-ion chelating agents because of its structural characteristics and excellent functional activities. In this study, we synthesized and characterized a novel Grifola frondosa polysaccharide-chromium (III) [GFP-Cr(III)] complex..

Shiitake · 2019 · Journal Article · Innovative Food Science and Emerging Technologies

Production of a β-d-glucan-rich extract from Shiitake mushrooms (Lentinula edodes) by an extraction/microfiltration/reverse osmosis (nanofiltration) process

A pilot-scale process combining extraction of Shiitake mushroom (Lentinula edodes) powder in water (98 °C, 1 h), cross-flow microfiltration and reverse osmosis (nanofiltration) was performed to obtain β-glucan-rich extracts..

OncologyImmune supportEnergy & fatigueMetabolic health

Zhu Ling · 2019 · Research Article · Molecules (Basel, Switzerland)

Quantitative Analysis of Polysaccharide Composition in Polyporus umbellatus by HPLC-ESI-TOF-MS.

Polyporus umbellatus is a well-known and important medicinal fungus in Asia. Its polysaccharides possess interesting bioactivities such as antitumor, antioxidant, hepatoprotective and immunomodulatory effects..

King Oyster · 2019 · Journal Article · Journal of microbiology and biotechnology

Ralstonia pickettii Enhance the DDT Biodegradation by Pleurotus eryngii.

DDT is a hydrophobic organic pollutant, which can be bio-accumulated in nature and have adverse consequences on the physical condition of humans and animals. This study investigated the relationship between the white-rot fungus Pleurotus eryngii and biosurfactantproducing bacterium Ralstonia pickettii associated with….

Chaga · 2019 · Journal Article · Annals of microbiology

Screening and identification of a Penicillium brevicompactum strain isolated from the fruiting body of Inonotus obliquus and the fermentation production of mycophenolic acid

PURPOSE: Mycophenolic acid (MPA) is a fungal metabolite with a variety of biological activities and widely applied in clinical practices. We herein aimed to isolate a new Penicillium brevicompactum strain from the fruiting body of Inonotus obliquus to improve the production of MPA..

Cordyceps · 2019 · Journal Article · International journal of biological macromolecules

Structural characterisation and cholesterol efflux improving capacity of the novel polysaccharides from Cordyceps militaris.

Water extracts of the edible mushroom Cordyceps militaris possess a lipid-lowering effect. However, the types of components and how they exert this effect are not clear.

Immune supportMetabolic healthGut & microbiomeRespiratory

Turkey Tail · 2019 · Research Article · BMC complementary and alternative medicine

The mycelium of the Trametes versicolor (Turkey tail) mushroom and its fermented substrate each show potent and complementary immune activating properties in vitro.

BACKGROUND: The medicinal mushroom Trametes versicolor (Tv, Turkey Tail) is often prepared for consumption as a powder from the fungal mycelium and the fermented substrate on which it grew..

Mesima · 2019 · Research Article · BMC complementary and alternative medicine

The protective effect of Phellinus linteus decoction on podocyte injury in the kidney of FSGS rats.

BACKGROUND: This study aimed to investigate the effect of the Phellinus linteus (Mesima) decoction on podocyte injury in a rat model of focal and segmental glomerulosclerosis (FSGS) and evaluate the potential mechanisms..

Cognition & nervesMetabolic health

Lion's Mane · 2019 · Journal Article · International journal of medicinal mushrooms

Thirteen-Week Oral Toxicity Evaluation of Erinacine AEnriched Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), Mycelia in Sprague-Dawley Rats.

Recently, erinacine A-enriched Hericium erinaceus (EAHE) mycelia have demonstrated therapeutic efficacy in animal models of neurodegenerative disease, including Alzheimer and Parkinson disease. Despite promising results from animal models, there have been no reports on its toxicity after long-term consumption..

Cordyceps · 2019 · Research Article · Frontiers in microbiology

Transcriptome Analysis of Cordyceps militaris Reveals Genes Associated With Carotenoid Synthesis and Identification of the Function of the Cmtns Gene.

Cordyceps militaris, a valuable edible and medicinal fungus, has attracted increasing attention because of its various bioactive ingredients. However, the biosynthetic pathway of C.

Metabolic healthGut & microbiomeLiver support

King Oyster · 2019 · Journal Article · Journal of medicinal food

Water Extract of Pleurotus eryngii var. ferulae Prevents High-Fat Diet-Induced Obesity by Inhibiting Pancreatic Lipase.

Pleurotus eryngii var. ferulae (PEF) is traditionally used in the prevention and treatment of lifestyle-related diseases.

OncologyImmune supportMetabolic health

Maitake · 2019 · Journal Article · Food & function

Water-soluble polysaccharides from Grifola Frondosa fruiting bodies protect against immunosuppression in cyclophosphamide-induced mice via JAK2/STAT3/SOCS signal transduction pathways.

Grifola Frondosa, the king of mushrooms, is one of the most valued traditional medicines and has been used as a health food for a long time in China, Japan, and other Asian countries..

Energy & fatigueMetabolic healthSkin & hydration

Enoki · 2019 · Journal Article · International journal of medicinal mushrooms

Wound Healing Activity of a Skin Substitute from Residues of Culinary-Medicinal Winter Mushroom Flammulina velutipes (Agaricomycetes) Cultivation.

A skin substitute TG05 obtained from residues of the culinary-medicinal mushroom Flammulina velutipes cultivation process was developed in this study for the first time..

Immune supportMetabolic healthSkin & hydration

Oyster Mushroom · 2018 · Journal Article · Voprosy pitaniia

[The influence of the drying method for food properties and hypolidemic potential of oyster mushrooms (Pleurotus ostreatus)].

The aim of this research was to study the influence of two drying methods: freeze-drying sublimation and dry-air drying on the selected nutritional properties and hypolipidemic potential of fruiting bodies of oyster mushroom (Pleurotus ostreatus)..

Cordyceps · 2018 · Research Article · Toxicology research

A 90-day subchronic toxicity study of submerged mycelial culture of Cordyceps militaris in rats.

Cordyceps militaris (C. militaris) is a parasitic fungus that grows on the larvae of Lepidoptera.

Immune supportMetabolic healthLiver support

Cordyceps · 2018 · Research Article · Oxidative medicine and cellular longevity

Antioxidant and Hypoglycemic Effects of Acidic-Extractable Polysaccharides from Cordyceps militaris on Type 2 Diabetes Mice.

The present work was performed to evaluate the effect of acidic-extractable polysaccharides (AE-PS) from fruit bodies of Cordyceps militaris on type 2 diabetes mellitus (T2DM) and its structural characteristics..

King Oyster · 2018 · Journal Article · International journal of biological macromolecules

Antioxidation, anti-hyperglycaemia and renoprotective effects of extracellular polysaccharides from Pleurotus eryngii SI-04.

The present study was designed to investigate the anti-hyperglycaemia, hypolipidemia and renoprotective effects of two extracellular polysaccharides (EPS) from the broth of Pleurotus eryngii SI-04 (EPS1 and EPS2) in mice with streptozotocin (STZ)-induced diabetic nephropathy (DN)..

Cordyceps · 2018 · Research Article · Journal of diabetes research

Artificially Cultivated Ophiocordyceps sinensis Alleviates Diabetic Nephropathy and Its Podocyte Injury via Inhibiting P2X7R Expression and NLRP3 Inflammasome Activation.

BACKGROUND/AIMS: It is known that chronic low-grade inflammation contributes to the initiation and development of both diabetes and diabetic nephropathy (DN), so we designed this study to investigate the role of P2X7R and NLRP3 inflammasome in DN pathogenesis and the antagonistic effects of artificially cultivated….

Oyster Mushroom · 2018 · Research Article · Food science & nutrition

Bioprospecting of powdered pineapple rind as an organic supplement of composted sawdust for Pleurotus ostreatus mushroom cultivation.

Pineapple rind is a by-product of the pineapple processing industry and contains nutrients and other compounds which must be utilized as a bioresource for socio-economic benefits while preventing the potential problems of improper agroindustrial biomass disposal methods..

Immune supportMetabolic healthLiver support

King Oyster · 2018 · Research Article · Oxidative medicine and cellular longevity

Characterization and Attenuation of Streptozotocin-Induced Diabetic Organ Damage by Polysaccharides from Spent Mushroom Substrate (Pleurotus eryngii).

The aim of this work was to characterize spent mushroom substrate polysaccharides (MSP) from Pleurotus eryngii and their antioxidant and organ protective effects in streptozotocin- (STZ-) induced diabetic mice. The enzymatic-, acidic-, and alkalic- (En-, Ac-, and Al-) MSP were extracted from P..

King Oyster · 2018 · Journal Article · International journal of food science & technology

Chemical characterisation and hypolipidaemic effects of two purified Pleurotus eryngii polysaccharides

This study is focused on the isolation and characterisation of two purified polysaccharide fractions (namely PPEP‐1 and PPEP‐2) from Pleurotus eryngii (P. eryngii) and evaluation of their hypolipidaemic effects.

Chaga · 2018 · Research Article · Molecules (Basel, Switzerland)

Chemical Characterization and Hypoglycaemic Activities In Vitro of Two Polysaccharides from Inonotus obliquus by Submerged Culture.

Polysaccharides from the fungus Inonotus obliquus have been found to be biologically active. In this study, we carried out a preliminary characterisation and assessment of the hypoglycaemic activities of the polysaccharides (IOEP) from Inonotus obliquus obtained by liquid fermentation..

OncologyImmune supportEnergy & fatigueMetabolic health

Cordyceps · 2018 · Research Article · Polymers

Effects of Different Temperatures on the Chemical Structure and Antitumor Activities of Polysaccharides from Cordyceps militaris.

The effects of different extraction temperatures (4 and 80 °C) on the physicochemical properties and antitumor activity of water soluble polysaccharides (CMPs-4 and CMPs-80) from Cordyceps militaris (C. militaris) were evaluated in this study..

Energy & fatigueMetabolic healthGut & microbiome

Cordyceps · 2018 · Research Article · Journal of animal science

Effects of spent mushroom Cordyceps militaris supplementation on apparent digestibility, rumen fermentation, and blood metabolite parameters of goats.

The objective of this experiment was to study the effects of dried spent mushroom Cordyceps militaris (SMCM) supplementation on digestibility, rumen fermentation, and blood metabolite parameters in goats. When the mushroom production and harvesting was complete, SMCM was collected fresh from a mushroom farm..

Cordyceps · 2018 · Journal Article · Bioresource technology

Enhancing cordycepin production in liquid static cultivation of Cordyceps militaris by adding vegetable oils as the secondary carbon source.

This study evaluated different vegetable oils as the second carbon source in liquid static culture of Cordyceps militaris in terms of mycelial growth and cordycepin production. The maximum mycelial concentration and cordycepin production were observed under cottonseed oil and peanut oil induction, respectively..

Immune supportMetabolic healthSkin & hydration

Enoki · 2018 · Journal Article · International journal of food science & technology

Enzymatic hydrolysis combined with high‐pressure homogenisation for the preparation of polysaccharide‐based nanoparticles from the by‐product of Flammulina velutipes

In this study, protease, α‐amylase and 5‰ β‐glucanase enzymolysis in combination with high‐pressure homogenisation were used for the preparation of polysaccharide‐based nanoparticles from Flammulina velutipes stipes, respectively, named FNP‐1, FNP‐2 and FNP‐3, and the nanoparticles were subsequently characterised..

Energy & fatigueMetabolic healthLiver support

Reishi · 2018 · Journal Article · International journal of medicinal mushrooms

Evaluation of the Antioxidative and Hypo-cholesterolemic Effects of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), in Ameliorating Cardiovascular Disease.

Oxidative stress (OS) and hypercholesterolemia have been linked with a heightened risk of cardiovascular disease (CVD). Because of the numerous drawbacks of synthetic antioxidants and cholesterol-lowering drugs, natural antioxidative and hypocholesterolemic agents are of immense importance..

Energy & fatigueMetabolic health

Maitake · 2018 · Journal Article · Bioscience, biotechnology, and biochemistry

Grifola frondosa (Maitake) extract activates PPARδ and improves glucose intolerance in high-fat diet-induced obese mice.

Grifola frondosa is a mushroom that has anti-obesity effects, but the detailed mechanism is poorly understood. In this study, we found that lipid soluble extracts derived from G..

OncologyImmune supportMetabolic healthGut & microbiome

Reishi · 2018 · Journal Article · Journal of medicinal food

Hypolipidemic, Antioxidant, and Antiapoptotic Effects of Polysaccharides Extracted from Reishi Mushroom, Ganoderma lucidum (Leysser: Fr) Karst, in Mice Fed a High-Fat Diet.

The mechanisms underlying the effect of Ganoderma lucidum (Reishi mushroom) polysaccharides (GLP) on obesity are not clear. In this study, GLP were found to attenuate the oleic acid-induced cell viability loss and apoptosis dose dependently in splenic lymphocytes in vitro..

Cognition & nervesMetabolic health

Reishi · 2018 · Journal Article · Phytomedicine: international journal of phytotherapy and phytopharmacology

Hypotensive and neurometabolic effects of intragastric Reishi (Ganoderma lucidum) administration in hypertensive ISIAH rat strain.

BACKGROUND: As the standard clinically used hypotensive medicines have many undesirable side effects, there is a need for new therapeutic agents, especially ones of a natural origin..

OncologyImmune supportMetabolic healthLiver support

Cordyceps · 2018 · Research Article · Laboratory animal research

Inhibition of endoplasmic reticulum stress in high-fat-diet-induced obese C57BL/6 mice: Efficacy of a novel extract from mulberry (Morus alba) leaves fermented with Cordyceps militaris.

A few clues about correlation between endoplasmic reticulum (ER) stress and mulberry (Morus alba) leaves were investigated in only the experimental autoimmune myocarditis and streptozotocin-induced diabetes..

Immune supportMetabolic healthGut & microbiome

Lion's Mane · 2018 · Journal Article · International journal of biological macromolecules

Isolation, purification and physicochemical properties of polysaccharide from fruiting body of Hericium erinaceus and its effect on colonic health of mice.

Hericium erinaceus was extracted with boiling water to obtain the crude polysaccharide (HECP) and refined polysaccharide (HERP). HERP was further purified using gradual ethanol precipitation to obtain five sub-fractions..

Immune supportEnergy & fatigueMetabolic healthLiver support

King Oyster · 2018 · Research Article · Polymers

Lipid-Lowering Effect of the Pleurotus eryngii (King Oyster Mushroom) Polysaccharide from Solid-State Fermentation on Both Macrophage-Derived Foam Cells and Zebrafish Models.

Hyperlipidemia is a key risk factor in inducing fatty liver, hypertension, atherosclerosis and cerebrovascular diseases. Previous studies have verified that polysaccharides from fruiting bodies (PEPE) of Pleurotus eryngii (king oyster mushroom) are capable of decreasing the lipid content.

Cordyceps · 2018 · Journal Article · Biomedical chromatography: BMC

Metabolomic comparison between wild Ophiocordyceps sinensis and artificial cultured Cordyceps militaris.

A systematic study on the metabolome differences between wild Ophiocordyceps sinensis and artificial cultured Cordyceps militaris was conducted using liquid chromatography-mass spectrometry. Principal component analysis and orthogonal projection on latent structure-discriminant analysis results showed that C..

Immune supportEnergy & fatigueMetabolic health

Enoki · 2018 · Research Article · Experimental biology and medicine (Maywood, N.J.)

Myo- and cardiotoxic effects of the wild winter mushroom ( Flammulina velutipes) on mice.

Rhabdomyolysis (destruction of striated muscle) is a novel form of mushroom poisoning in Europe and Asia indicated by increased circulating creatine kinase levels. Particular wild fungi have also been reported to induce elevated creatine kinase activities in mice..

Immune supportMetabolic healthLiver support

Cordyceps · 2018 · Research Article · RSC advances

Structural characterization of polysaccharides from Cordyceps militaris and their hypolipidemic effects in high fat diet fed mice.

Cordyceps militaris is a crude dietary therapeutic mushroom with high nutritional and medicinal values. Mushroom-derived polysaccharides have been found to possess antihyperglycemic and antihyperlipidemic activities..

Cognition & nervesMetabolic health

Lion's Mane · 2018 · Research Article · International journal of molecular sciences

The Cyanthin Diterpenoid and Sesterterpene Constituents of Hericium erinaceus Mycelium Ameliorate Alzheimer's Disease-Related Pathologies in APP/PS1 Transgenic Mice.

Hericium erinaceus was used in traditional Chinese medicine for physiologically beneficial medicines. Recently, it has become a candidate in causing positive brain health-related activities.

Shiitake · 2018 · Journal Article · International journal of food science & technology

The effect and mechanism of ultrasonic treatment on the postharvest texture of shiitake mushrooms (Lentinula edodes)

Fresh shiitake mushrooms (Lentinula edodes) are prone to texture softening and quality decline during storage. We investigated the effects of prestorage ultrasonic treatment on the textural changes of the mushrooms during storage..

King Oyster · 2018 · Journal Article · Chemosphere

Transcriptome analysis reveals the role of nitric oxide in Pleurotus eryngii responses to Cd2+ stress.

Pleurotus eryngii is widely cultivated in China. However, our understanding of its transcriptional response to heavy metal stress and the underlying mechanism of nitric oxide (NO) in enhancing its tolerance to heavy metals is limited..