MycoData

Childhood cancer survivors are at increased risk for second primary leukemia (SPL), but there is little consensus on the magnitude of some risk factors because of the small size of previous studies..

Oncology

Medium relevance

Shiitake · 2021 · Journal Article · Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes

Sensitivity of Trichoderma strains from edible mushrooms to the fungicides prochloraz and metrafenone.

Twenty-two strains of Trichoderma spp. (T.

Medium relevance

Almond Mushroom · 2021 · Journal Article · Infectious diseases (London, England)

Serum levels of neurofilament light chain, neuron-specific enolase and S100 calcium-binding protein B during acute bacterial meningitis: a prospective cohort study.

PURPOSE: Acute bacterial meningitis (ABM) is a severe disease with an overall poor outcome. Neurofilament (NFL) has shown to be a promising biomarker of neuroaxonal injury in various neurological disorders but has not been investigated in ABM..

Cognition & nerves

Medium relevance

Almond Mushroom · 2021 · Journal Article · Molecular microbiology

Shigella flexneri subverts host polarized exocytosis to enhance cell-to-cell spread.

Shigella flexneri is a gram-negative bacterial pathogen that causes dysentery. Critical for disease is the ability of Shigella to use an actin-based motility (ABM) process to spread between cells of the colonic epithelium..

Gut & microbiome

Medium relevance

Almond Mushroom · 2021 · Research Article · Emerging themes in epidemiology

Situating agent-based modelling in population health research.

Today's most troublesome population health challenges are often driven by social and environmental determinants, which are difficult to model using traditional epidemiological methods. We agree with those who have argued for the wider adoption of agent-based modelling (ABM) in taking on these challenges..

Medium relevance

Almond Mushroom · 2021 · Journal Article · Biomaterials science

Structural influence of antibody recruiting glycodendrimers (ARGs) on antitumoral cytotoxicity.

The recruitment of endogenous antibodies against cancer cells has become a reliable antitumoral immunotherapeutic alternative over the last decade. The covalent attachment of antibody and tumor binding modules (ABM and TBM) within a single, well-defined synthetic molecule was indeed demonstrated to promote the….

OncologyImmune support

Medium relevance

Almond Mushroom · 2021 · Journal Article · Journal of environmental management

Testing a norm-based policy for waste management: An agent-based modeling simulation on nudging recycling behavior.

The present study uses agent-based modeling (ABM) to examine the effectiveness of a nudge policy for improving recycling behavior. In our simulation, agents' recycling behavior is computed by components of the Theory of Planned Behaviour (i.e., attitudes, perceived behavioral control, social norms) and influenced by….

Medium relevance

Almond Mushroom · 2021 · Journal Article · Aquaculture

The stress of abamectin toxicity reduced water quality, growth performance, immunity and antioxidant capacity of Oreochromis niloticus fish: Modulatory role of Simmondsia chinensis extract as a dietary supplement

The present study was conducted to investigate the toxic effect of abamectin (ABM) and to evaluate the modulatory role of heat treated jojoba leaves extract (JLE) as feed additive in Oreochromis niloticus (O. niloticus) fish..

Immune supportEnergy & fatigueMetabolic healthLiver support

Medium relevance

Almond Mushroom · 2021 · Journal Article · Frontiers in physiology

The Use of Artificial Neural Networks to Forecast the Behavior of Agent-Based Models of Pathophysiology: An Example Utilizing an Agent-Based Model of Sepsis.

Introduction: Disease states are being characterized at finer and finer levels of resolution via biomarker or gene expression profiles, while at the same time. Machine learning (ML) is increasingly used to analyze and potentially classify or predict the behavior of biological systems based on such characterization..

Immune supportCognition & nerves

Medium relevance

King Oyster · 2021 · Journal Article · Enzyme and microbial technology

Use of green light to improve the production of lignocellulose-decay enzymes by Pleurotus spp. in liquid cultivation.

The influence of green light on mycelium biomass growth and extracellular enzyme activities of edible mushrooms from the Pleurotus genus, which is popularly cultivated all over the world, were investigated. The mycelium of seven strains of five species of Pleurotus (P.

Medium relevance

Almond Mushroom · 2021 · Research Article · Frontiers in physiology

Utilizing the Heterogeneity of Clinical Data for Model Refinement and Rule Discovery Through the Application of Genetic Algorithms to Calibrate a High-Dimensional Agent-Based Model of Systemic Inflammation.

Introduction: Accounting for biological heterogeneity represents one of the greatest challenges in biomedical research. Dynamic computational and mathematical models can be used to enhance the study and understanding of biological systems, but traditional methods for calibration and validation commonly do not account….

Immune supportCognition & nerves

Medium relevance

Almond Mushroom · 2021 · Research Article · Cognitive therapy and research

What's in a Face? Amygdalar Sensitivity to an Emotional Threatening Faces Task and Transdiagnostic Internalizing Disorder Symptoms in Participants Receiving Attention Bias Modification Training.

BACKGROUND: Altered amygdala activation in response to the emotional matching faces (EMF) task, a task thought to reflect implicit emotion detection and reactivity, has been found in some patients with internalizing disorders; mixed findings from the EMF suggest individual differences (within and/or across diagnoses)….

Cognition & nerves

Medium relevance

Cordyceps · 2020 · Video Audio Media · Journal of visualized experiments: JoVE

Gene Mining and Sequence Analysis of Purine Nucleosidase Based on RNA-Seq.

Caterpillar fungus (Ophiocordyceps sinensis) is one of the most valued fungal Traditional Chinese medicine (TCM), and it contains plenty of active ingredients such as adenosine. Adenosine is considered as a biologically effective ingredient that has a variety of anti-tumor and immunomodulatory activities..

OncologyImmune support

Medium relevance

King Oyster · 2020 · Research Support, Non U.S. Gov'T · Scientific reports

Iron biofortification and availability in the mycelial biomass of edible and medicinal basidiomycetes cultivated in sugarcane molasses.

Basidiomycetes can bioaccumulate high iron contents, but there are few studies on iron availability from the mycelial biomass in order to support their use as an iron-enriched fungal food..

Medium relevance

Oyster Mushroom · 2019 · Research Support, Non U.S. Gov'T · Scientific reports

Elemental imaging by Laser-Induced Breakdown Spectroscopy to evaluate selenium enrichment effects in edible mushrooms.

Mushrooms are bioaccumulating organisms commonly used in selenium (Se) enrichment studies. However, the addition of Se in the culture medium may alter the distribution of other essential elements in the mushroom fruiting body..

Medium relevance

Oyster Mushroom · 2019 · Research Support, Non U.S. Gov'T · Food research international (Ottawa, Ont.)

Multivariate optimization of extraction and validation of phenolic acids in edible mushrooms by capillary electrophoresis.

A "green" analytical method is reported for the determination of phenolic acids in mushrooms. The sample preparation involves aqueous extraction based on acid hydrolysis, followed by analysis of extracts by capillary electrophoresis with diode array detector (CE-DAD)..

Energy & fatigue

Medium relevance

Oyster Mushroom · 2017 · Research Support, Non U.S. Gov'T · Journal of economic entomology

Effects of Feeding on Different Host Plants and Diets on Bradysia Odoriphaga Population Parameters and Tolerance to Heat and Insecticides.

Bradysia odoriphaga Yang et Zhang, the Chinese chive root maggot, is a devastating pest of agricultural plants causing significant losses in vegetable crops, edible mushrooms, and humus. To determine the effects of feeding on different host plants and diets on the life parameters of B..

Medium relevance

King Oyster · 2016 · Research Support, Non U.S. Gov'T · Applied and environmental microbiology

Activities of Secreted Aryl Alcohol Quinone Oxidoreductases from Pycnoporus cinnabarinus Provide Insights into Fungal Degradation of Plant Biomass.

Auxiliary activities family 3 subfamily 2 (AA3_2) from the CAZy database comprises various functions related to ligninolytic enzymes, such as fungal aryl alcohol oxidases (AAO) and glucose oxidases, both of which are flavoenzymes..

Energy & fatigueMetabolic health

Medium relevance

King Oyster · 2016 · Comparative Study · Canadian journal of microbiology

Equilibrium and kinetic studies on biosorption of Pb(II) by common edible macrofungi: a comparative study.

In this work, we studied the natural bioaccumulation and biosorption of Pb(II) in several common edible macrofungi. The macrofungi include the following species: Lentinus edodes, Pleurotus eryngii, Flammulina velutipes, Hypsizygus marmoreus, and Agrocybe cylindracea..

Medium relevance

Shiitake · 2016 · Brief Report · Indian journal of microbiology

Investigating the Effect of Tissue Size on Mycelial Growth of Seven Mushroom Species by Using a Novel Device for Precise Tissue Isolation.

Tissue isolation from mushrooms is frequently practiced by both researchers and growers to isolate new and improved strains. In the present study, we designed a simple and convenient device for precise tissue isolation and therefore investigated the effect of tissue size on mycelial growth of seven mushroom species..

Medium relevance

Chaga · 2015 · Journal Article · International journal of food science & technology

Chemical composition and antioxidant properties of five edible Hymenomycetes mushrooms

Ethanol extracts (LEE: ethanol extract from Lentinus edodes; TEE: ethanol extract from Tremella fuciformis; AEE: ethanol extract from Auricularia polytricha; GEE: ethanol extract from Ganoderma lucidum; IEE: ethanol extract from Inonotus obliquus) and water extracts (LWE: water extract from Lentinus edodes; TWE: water….

Medium relevance

King Oyster · 2015 · Journal Article · Chemistry & biodiversity

Chemical Composition and Character Impact Odorants in Volatile Oils from Edible Mushrooms.

The aim of this study was to investigate the chemical composition and the odor-active components of volatile oils from three edible mushrooms, Pleurotus ostreatus, Pleurotus eryngii, and Pleurotus abalonus, which are well-known edible mushrooms..

Medium relevance

King Oyster · 2015 · Journal Article · Eur Food Res Technol

Supplementation of cultivated mushroom species with selenium: bioaccumulation and speciation study

Selenium (Se) is a highly essential element, intakes of which in many populations are below the established requirements. As edible mushrooms represent an important part of the human diet in some regions, the present study investigated the concentrations of Se species (Se(IV), Se(VI), Seₒᵣg and Seₜₒₜₐₗ) in three….

Medium relevance

King Oyster · 2015 · Journal Article · Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire

The effect of selenium on phenolics and flavonoids in selected edible white rot fungi

The objective of the study was to determine total phenolic and flavonoid content and composition as well as antioxidant activity in Pholiota nameko, Pleurotus eryngii and Pleurotus ostreatus growing on substrates supplemented with selenium salts..

Medium relevance

King Oyster · 2014 · Journal Article · Applied biochemistry and biotechnology

Construction of a laccase chimerical gene: recombinant protein characterization and gene expression via yeast surface display.

The ERY4 laccase gene from Pleurotus eryngii was expressed in Saccharomyces cerevisiae and the recombinant laccase resulted to be not biologically active. This gene was thus modified to obtain chimerical enzymes derived from the substitution of N-, C- and both N- and C-terminal regions with the corresponding regions….

Immune supportEnergy & fatigue

Medium relevance

King Oyster · 2014 · Journal Article · Plant disease

First Report of Pantoea beijingensis Induced Soft Rot Disease of Pleurotus nebrodensis in China.

Pleurotus nebrodensis is a popular edible fungus in China. In December 2009, soft rot disease appeared on fruiting bodies of P.

Gut & microbiome

Medium relevance

King Oyster · 2013 · Journal Article · International journal of medicinal mushrooms

Antibacterial activity of Mediterranean Oyster mushrooms, species of genus Pleurotus (higher Basidiomycetes).

Extracts of the Mediterranean culinary-medicinal Oyster mushrooms Pleurotus eryngii var. eryngii, P.

Skin & hydration

Medium relevance

King Oyster · 2013 · Journal Article · International journal of food properties

Antioxidant Properties of Cultured Mycelia from Four Pleurotus Species Produced in Submerged Medium

The ethanolic extracts of dried cultured mycelia of Pleurotus ostreatus, Pleurotus eryngii, Pleurotus florida, and Pleurotus sajor-caju were analyzed for antioxidant activity in different systems..

Medium relevance

King Oyster · 2012 · Journal Article · Plant disease

First Report of Cobweb on White Button Mushroom (Agaricus bisporus) in Spain Caused by Cladobotryum mycophilum.

Between 2008 and 2011, symptoms of cobweb were observed in commercial white button mushroom (Agaricus bisporus) crops in Castilla-La Mancha (Spain). Typical symptoms started as white, cobweb-like mycelial growth over the surface of the casing soils and fruiting bodies..

Gut & microbiome

Medium relevance

King Oyster · 2012 · Journal Article · European journal of plant pathology

Identification and RAPD-typing of Ewingella americana on cultivated mushrooms in Castilla-La Mancha, Spain

Ewingella americana was identified as the causal agent of internal stipe necrosis on symptomatic samples collected from mushroom farms located in Castilla-La Mancha, Spain, during the years 2008 to 2010..

Medium relevance

King Oyster · 2011 · Journal Article · Food chemistry

Cyanobacteria produce high levels of ergothioneine

Ergothioneine (ET) is a unique natural antioxidant. We have examined the origin of ET in zebrafish.

Medium relevance

King Oyster · 2011 · Journal Article · Animal feed science and technology

Improving ruminal degradability of oil palm fronds using white rot fungi

The use of oil palm fronds (OPF) in livestock production is limited as up to 0.20 of their dry biomass is lignin. White rot fungi (WRF) are very effective basidiomycetes for biological pre-treatment as they degrade lignin extensively..

Gut & microbiome

Medium relevance

Almond Mushroom · 2011 · Research Article · Journal of clinical biochemistry and nutrition

Ipomoea batatas and Agarics blazei ameliorate diabetic disorders with therapeutic antioxidant potential in streptozotocin-induced diabetic rats

Ipomoea batatas, Agaricus blazei and Smallanthus sonchifolius are known to favorably influence diabetes mellitus. To clarify their antidiabetic efficacy and hypoglycemic mechanisms, we treated streptozotocin-induced diabetic rats with daily oral feeding of powdered Ipomoea batatas (5 g kg(-1) d(-1)), Agaricus blazei….

OncologyImmune supportCognition & nervesMetabolic health

Medium relevance

King Oyster · 2011 · Journal Article · Food chemistry

Protective effect of two edible mushrooms against oxidative cell damage and their phenolic composition

The aim of the study was to investigate phenolic composition, antioxidative, protective and cytotoxic effects of Pleurotus eryngii and Auricularia auricula-judae. Analysis of phenolic compounds in these edible mushrooms species has been carried out by high-performance liquid chromatography (HPLC)..

OncologyEnergy & fatigue

Medium relevance

Turkey Tail · 2008 · Journal Article · Wood Sci Technol

Detection of incipient decay in tree stems with sonic tomography after wounding and fungal inoculation

Picus® acoustic tomography was used to map incipient stages of fungal decay in the sapwood of standing Douglas fir, beech, oak, and sycamore trees 2, 16, and 27 months after wounding and artificial inoculation with brown-, soft-, and white-rot decay fungi..

Skin & hydration

Medium relevance

King Oyster · 2006 · Journal Article · Applied biochemistry and biotechnology

Effect of copper and manganese ions on activities of laccase and peroxidases in three Pleurotus species grown on agricultural wastes.

Copper (Cu2+) and manganese (Mn2+) ions influenced laccase (Lac) and peroxidase production in Pleurotus eryngii, Pleurotus ostreatus, and Pleurotus pulmonarius. In P..

Medium relevance

Reishi · 2023 · Research Support, Non U.S. Gov'T · Food research international (Ottawa, Ont.)

3D printable vegan plant-based meat analogue: Fortification with three different mushrooms, investigation of printability, and characterization.

In this study, a meat analogue formulation prepared using different protein sources as a printable ink for 3D printers and fortified with three different mushroom cultivars (reishi, Ganoderma lucidum (GL); saffron milk-cap, Lactarius deliciosus (LD); and oyster, Pleurotus ostreatus (PO))..

Energy & fatigueSkin & hydration

Medium relevance

Cordyceps · 2023 · Research Support, Non U.S. Gov'T · Molecular ecology

Fine-scale genome-wide signature of Pleistocene glaciation in Thitarodes moths (Lepidoptera: Hepialidae), host of Ophiocordyceps fungus in the Hengduan Mountains.

The Hengduan Mountains region is a biodiversity hotspot known for its topologically complex, deep valleys and high mountains. While landscape and glacial refugia have been evoked to explain patterns of interspecies divergence, the accumulation of intra-species (i.e., population level) genetic divergence across the….

Medium relevance

Cordyceps · 2023 · Research Support, Non U.S. Gov'T · ACS synthetic biology

Increased Cordycepin Production in Yarrowia lipolytica Using Combinatorial Metabolic Engineering Strategies.

As the first nucleoside antibiotic discovered in fungi, cordycepin, with its various biological activities, has wide applications. At present, cordycepin is mainly obtained from the natural fruiting bodies of Cordyceps militaris..

Metabolic health

Medium relevance

King Oyster · 2023 · Research Support, Non U.S. Gov'T · Protein science: a publication of the Protein Society

Role and structure of the small subunit forming heterodimers with laccase-like enzymes.

Unlike laccases sensu stricto, which are usually monomeric enzymes, laccase-like enzymes recently re-classified as Novel Laccases (NLACs) are characterized by the formation of heterodimers with small proteins (subunits) of unknown function..

Medium relevance

Cordyceps · 2022 · Research Support, Non U.S. Gov'T · Biochemical and biophysical research communications

Cordycepin exhibits anti-fatigue effect via activating TIGAR/SIRT1/PGC-1α signaling pathway.

Fatigue, a most commonly sub-health condition, may cause people more susceptible to many diseases. Cordycepin, a principal active ingredient from Cordyceps militaris, exerts various pharmacological activities including anti-diabetes, anti-inflammatory, immunomodulatory and antioxidant effects..

Immune supportEnergy & fatigueMetabolic healthLiver support

Medium relevance

Cordyceps · 2022 · Research Support, Non U.S. Gov'T · BMC pharmacology & toxicology

Cordycepin inhibits colon cancer proliferation by suppressing MYC expression.

BACKGROUND: Cordycepin is a purine nucleoside anti-metabolite and anti-biotic isolated from the fungus Cordyceps militaris, which has potential anti-neoplastic activities. This study aimed to investigate the effect of cordycepin in inhibiting colon cancer development..

OncologyGut & microbiome

Medium relevance

Cordyceps · 2022 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

Cordycerebroside A inhibits ICAM-1-dependent M1 monocyte adhesion to osteoarthritis synovial fibroblasts.

Osteoarthritis (OA) is represented by the accumulation and adhesion of M1 macrophages into synovium tissues in the joint microenvironment and subsequent inflammatory response..

Immune support

Medium relevance

Oyster Mushroom · 2022 · Brief Report · Microbiology resource announcements

Draft Genome Sequence of Bacillus velezensis Strain Krd-20 with Antifungal Activity, a Biotechnologically Important Isolate from Wheat Root Zone.

Bacillus velezensis Krd-20 strain with antifungal activity was isolated from the wheat rhizosphere. This strain is used to suppress fungi of the Fusarium sp.

Medium relevance

Cordyceps · 2022 · Research Support, Non U.S. Gov'T · Developmental and comparative immunology

Immulectin-2 from the ghost moth, Thitarodes xiaojinensis (Lepidoptera: Hepialidae), modulates cellular and humoral responses against fungal infection.

C type-lectins constitute a large family of pattern recognition receptors, playing important roles in insect immune defenses. Thitarodes xiaojinensis larvae showed distinct immune features after Ophiocordyceps sinensis, Cordyceps militaris, or Beauveria bassiana infection..

Immune supportCognition & nerves

Medium relevance

King Oyster · 2022 · Research Support, Non U.S. Gov'T · Frontiers in immunology

Immune regulatory functions of biologically active proteins from edible fungi.

Proteins from edible mushrooms have a variety of biological activities. Here, thirteen precious edible mushrooms such as Ophiocordyceps sinensis, Ganoderma lucidum, and Morchella esculenta and nine common edible mushrooms such as Flammulina velutipes, Pleurotus ostreatus, and Pleurotus eryngii, etc., from which their….

Immune supportEnergy & fatigue

Medium relevance

Lion's Mane · 2022 · Research Support, Non U.S. Gov'T · Scientific reports

Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month relative to non-microdosing controls.

Psilocybin microdosing involves repeated self-administration of mushrooms containing psilocybin at doses small enough to not impact regular functioning. Microdose practices are diverse and include combining psilocybin with substances such as lion's mane mushrooms (Hericium erinaceus; HE) and niacin (vitamin-B3)..

Energy & fatigue

Medium relevance

Cordyceps · 2022 · Research Support, Non U.S. Gov'T · Integrative cancer therapies

Synergistic Effect of HAD-B1 and Afatinib Against Gefitinib Resistance of Non-Small Cell Lung Cancer.

In epidermal growth factor receptor (EGFR) mutant non-small cell lung cancer (NSCLC), acquired resistance to EGFR tyrosine kinase inhibitors (TKI) leads to disease progression. Strategies to overcome the resistance are required in treatment for advanced lung cancer..

OncologySkin & hydrationRespiratory

Medium relevance

Cordyceps · 2021 · Research Support, Non U.S. Gov'T · Neurotoxicology

Anti-inflammatory and neuroprotective effects of natural cordycepin in rotenone-induced PD models through inhibiting Drp1-mediated mitochondrial fission.

Accumulating evidences suggest that inflammation-mediated neurons dysfunction participates in the initial and development of Parkinson's disease (PD), whereas mitochondria have been recently recognized as crucial regulators in NLRP3 inflammasome activation..

Immune supportCognition & nervesEnergy & fatigue

Medium relevance

Cordyceps · 2021 · Research Support, Non U.S. Gov'T · Hepatology (Baltimore, Md.)

Cordycepin Ameliorates Nonalcoholic Steatohepatitis by Activation of the AMP-Activated Protein Kinase Signaling Pathway.

BACKGROUND AND AIMS: Nonalcoholic fatty liver disease, especially nonalcoholic steatohepatitis (NASH), has become a major cause of liver transplantation and liver-associated death..

Immune supportMetabolic healthLiver support