MycoData

Immune supportMetabolic healthSkin & hydration

Almond Mushroom · 2022 · Journal Article · Electronic Journal of Biotechnology

Effects of Agaricus blazei acidic polysaccharide on the aging of mice through keap1-Nrf2/ARE and MAPKs signal pathway

In view of the increasing human life and the aging of the population, the search for safe anti-aging drugs has become a hot topic. Agaricus blazei Murrill is a rare edible fungus, with a variety of biological activities..

Cordyceps · 2022 · Research Article · Journal of fungi (Basel, Switzerland)

Efficacy of Cordyceps militaris Extracts against Some Skin Pathogenic Bacteria and Antioxidant Activity.

Cordyceps militaris has been used for treating various diseases, as well as maintaining good overall health. The antibacterial properties of the C.

Energy & fatigueSkin & hydration

King Oyster · 2022 · Journal Article · Journal of the science of food and agriculture

Influence of ultrasonic pretreatments on microwave hot-air flow rolling drying mechanism, thermal characteristics and rehydration dynamics of Pleurotus eryngii.

BACKGROUND: In order to improve the drying efficiency and reduce the drying energy consumption of Pleurotus eryngii, microwave hot-air flow rolling drying (MHARD) coupled with ultrasonic pretreating time (0, 20, 40, and 60 min) was used to investigate the drying profile, thermal characteristics, water migration,….

Energy & fatigueSkin & hydration

King Oyster · 2022 · Journal Article · Journal of the science of food and agriculture

Influence of ultrasonic pretreatments on microwave hot‐air flow rolling drying mechanism, thermal characteristics and rehydration dynamics of Pleurotus eryngii

BACKGROUND: In order to improve the drying efficiency and reduce the drying energy consumption of Pleurotus eryngii, microwave hot‐air flow rolling drying (MHARD) coupled with ultrasonic pretreating time (0, 20, 40, and 60 min) was used to investigate the drying profile, thermal characteristics, water migration,….

Reishi · 2022 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Lucidumol A, Purified Directly from Ganoderma lucidum, Exhibits Anticancer Effect and Cellular Inflammatory Response in Colorectal Cancer.

Colorectal cancer (CRC) is a deadly disease regardless of sex, and a few therapeutic approaches have been fully developed at advanced stages, even if some strategies have durable clinical benefits, such as immunotherapy and chemotherapy..

Metabolic healthSkin & hydration

Cordyceps · 2022 · Research Article · Microbial biotechnology

Multiplex gene precise editing and large DNA fragment deletion by the CRISPR-Cas9-TRAMA system in edible mushroom Cordyceps militaris.

The medicinal mushroom Cordyceps militaris contains abundant valuable bioactive ingredients that have attracted a great deal of attention in the pharmaceutical and cosmetic industries. However, the development of this valuable mushroom faces the obstacle of lacking powerful genomic engineering tools..

King Oyster · 2022 · Research Article · Frontiers in nutrition

Reduction of oil uptake in vacuum fried Pleurotus eryngii chips via ultrasound assisted pretreatment.

The reduction of oil uptake in vacuum-fried Pleurotus eryngii chips by ultrasound assisted pretreatment was investigated regarding the pore structure changes. Pore structure of P..

Enoki · 2022 · Journal Article · International journal of medicinal mushrooms

Residues of Culinary-Medicinal Winter Mushroom, Flammulina velutipes (Agaricomycetes), Cultivation as a Potential Source of Functional Skin Substitute with Multiple Bioactivities.

Residues generated during the cultivation of edible mushroom Flammulina velutipes are abundant and utilized with low efficiency. In this study, the composition and bioactivities of a skin substitute named TG05 obtained from residues of the F.

Shiitake · 2022 · Journal Article · Food research international (Ottawa, Ont.)

Umami Ingredient: Flavor enhancer from shiitake (Lentinula edodes) byproducts

An alternative use of shiitake stipes, usually treated as waste, was proposed for the production of a powder ingredient, rich in umami compounds, aiming its application in food..

Immune supportCognition & nervesEnergy & fatigueSkin & hydration

Almond Mushroom · 2021 · Journal Article · Journal of food biochemistry

Agaricus blazei polypeptide exerts a protective effect on D‐galactose‐induced aging mice via the Keap1/Nrf2/ARE and P53/Trim32 signaling pathways

This experiment mainly optimized the extraction technology of Agaricus blazei polypeptide (ABp) and evaluated its protective effect on aging mice. In this study, a novel single component, the M is 3 kD, was isolated and purified from Agaricus blazei.

Shiitake · 2021 · Journal Article · Food chemistry

An understanding of the changes in water holding capacity of rehydrated shiitake mushroom (Lentinula edodes) from cell wall, cell membrane and protein.

Water holding capacity (WHC) is an important factor for the evaluation of rehydrated shiitake mushroom as WHC largely affects sensory attributes. Here, WHC of the rehydrated shiitake mushroom as affected by different hot-air drying temperature was investigated from aspects of cell membrane integrity, status of cell….

Immune supportCognition & nervesLiver supportSkin & hydration

King Oyster · 2021 · Journal Article · International journal of biological macromolecules

Antioxidant and anti-ageing effects of enzymatic polysaccharide from Pleurotus eryngii residue.

The wide industrial cultivation of Pleurotus eryngii (P. eryngii) has resulted in the massive production of mushroom residues (MR) with low-efficiency utilization.

Chaga · 2021 · Research Article · Heliyon

Chaga mushroom (Inonotus obliquus) polysaccharides exhibit genoprotective effects in UVB-exposed embryonic zebrafish (Danio rerio) through coordinated expression of DNA repair genes.

Chaga mushroom is one of the promising beneficial mushrooms thriving in the colder parts of Northern hemisphere. Chaga polysaccharides (IOP) have been reported to enhance immune response and alleviate oxidative stress during development..

Cordyceps · 2021 · Research Article · ACS omega

Comparison of Ergosterol and Vitamin D2 in Mushrooms Agaricus bisporus and Cordyceps militaris Using Ultraviolet Irradiation Directly on Dry Powder or in Ethanol Suspension.

Vitamin D deficiency is a severe worldwide health issue. Edible mushrooms are an excellent vitamin D2 source and have gained popularity worldwide as a nutritional food..

Enoki · 2021 · Journal Article · International journal of biological macromolecules

Green fabrication of seedbed-like Flammulina velutipes polysaccharides-derived scaffolds accelerating full-thickness skin wound healing accompanied by hair follicle regeneration.

A novel seedbed-like scaffold was firstly fabricated by the "frozen sectioning" processing method using Flammulina velutipes as a raw material. The Flammulina velutipes polysaccharides scaffold is composed of a natural structure imitating the "ground" (connected and aligned hollow tubes with porous walls)..

Shiitake · 2021 · Research Article · Mycobiology

Pathological Properties of Cryptococcus pseudolongus on the Mycelia and Fruit Body of Lentinula edodes.

Recently, Cryptococcus pseudolongus has been reported as a new pathogen of shiitake (Lentinula edodes). However, its pathological properties are not much known.

Wood Ear · 2021 · Journal Article · International journal of medicinal mushrooms

Preparation of Wood Ear Medicinal Mushroom, Auricularia auricula-judae (Agaricomycetes), Melanin and Its Antioxidant Properties: Evaluation In Vitro and In Vivo.

This study investigated the extraction method of Auricularia auricula-judae melanin, focusing on the tough cell wall of the fruiting body and its free radical scavenging ability and antioxidant effects on Caenorhabditis elegans..

Cordyceps · 2021 · Research Article · Animal bioscience

Tenderness-related index and proteolytic enzyme response to the marination of spent hen breast by a protease extracted from Cordyceps militaris mushroom.

OBJECTIVE: The effects of a crude protease extracted from Cordyceps militaris (CM) mushrooms on the postmortem tenderization mechanism and quality improvement in spent hen breast were investigated..

Cordyceps · 2021 · Research Article · Journal of fungi (Basel, Switzerland)

The Feasibility of Utilizing Cultured Cordyceps militaris Residues in Cosmetics: Biological Activity Assessment of Their Crude Extracts.

Solid-based residues (SBRs) left from harvesting the fruiting bodies of cultured Cordyceps mushrooms are a challenge to sustainability. Therefore, in this study, the SBRs from the cultivation of Cordyceps militaris (C..

OncologySkin & hydration

Cordyceps · 2021 · Research Article · Frontiers in nutrition

Transcriptomic Responses of Cordyceps militaris to Salt Treatment During Cordycepins Production.

Cordycepin is a major bioactive compound found in Cordyceps militaris (C. militaris) that exhibits a broad spectrum of biological activities.

Snow Fungus · 2021 · Journal Article · Journal of cosmetic dermatology

Tremella fuciformis polysaccharides inhibit UVA-induced photodamage of human dermal fibroblast cells by activating up-regulating Nrf2/Keap1 pathways.

BACKGROUND: UVA radiation can cause skin oxidative stress. Tremella fuciformis polysaccharides (TFPS) are the main active ingredient in Tremella.

OncologyEnergy & fatigueSkin & hydration

Yellow Morel · 2021 · Journal Article · Preparative biochemistry & biotechnology

Utilization of Morchella esculenta-mediated green synthesis golden nanoparticles in biomedicine applications.

This study aimed to synthesize gold nanoparticles (AuNPs) by hot water extract in room conditions using edible Morchella esculenta (ME) and investigate the bioactive properties of the synthesized Morchella esculenta-based gold nanoparticles (ME-AuNPs)..

Snow Fungus · 2026 · Preprint · journal metadata

Beyond Conventional Drying: Improving the Quality of Dried Tremella fuciformis via a Heat-Integrated Pretreatment

Abstract Hot-air drying (HAD) of Tremella fuciformis often leads to poor rehydration, yellowing, and long preparation times, lowering its industrial value. This study introduces a heat-integrated pretreatment (HIP) as a simple and viable strategy to enhance the quality of dried product..

OncologyImmune supportGut & microbiomeSkin & hydration

Reishi · 2025 · Preprint · journal metadata

Study on the anti-tumor effect of Wall-broken Ganoderma lucidum spore powder on papillary thyroid cancer

Abstract Ganoderma lucidum wall-broken spores (BGLSP), traditionally used in Traditional Chinese Medicine for immunity and chronic diseases, contain bioactive triterpenoids with anti-tumor potential, but their mechanisms against papillary thyroid cancer (PTC) remain unclear..

Oyster Mushroom · 2024 · Preprint · journal metadata

Development and Characterization of a Value-Added Product Suitable for Food Applications from Agaricus bisporus and Pleurotus ostreatus Stems: Evaluation of Particle Size Influence and In Vitro Antioxidant Activity

The mushroom industry generates large amounts of stems, a co-product with valuable sensory and health characteristics. This work aimed to study the influence of particle size (L — >0.510 mm; LI — 0.510-0.315 mm; SI—0.315-0.180 mm; S — <0.180 mm) and species in the characterization and antioxidant activity of….

OncologyImmune supportMetabolic healthSkin & hydration

Snow Fungus · 2024 · Preprint · journal metadata

Overcharged lipid metabolism in mechanisms of antitumor by Tremella Fuciformis Polysaccharide

Tremella Fuciformis polysaccharides (TFP) is a natural macromolecular compound well-known for whitening, lipid and immunity regulation. To evaluate the effect of TFP on melanogenesis, lipid metabolism programmes and immune system of B16 cells in vitro and in vivo, the cell proliferation, cell cycle and apoptosis were….

King Oyster · 2022 · Research Article · Foods (Basel, Switzerland)

Incorporation of Mycelium (Pleurotus eryngii) in Pea Protein Based Low Moisture Meat Analogue: Effect on Its Physicochemical, Rehydration and Structural Properties.

The protein content of a plant-based ingredient is generally lower than its animal food counterpart, and research into novel alternative protein is required that can provide similar protein content, texture and appearance as meat..

Cordyceps · 2019 · Review · International journal of biological macromolecules

Advance in Cordyceps militaris (Linn) Link polysaccharides: Isolation, structure, and bioactivities: A review.

Cordyceps militaris is a unique and precious medical fungus in Chinese Cordyceps, which has been widely used as the traditional medicines or as biocontrol agents against pests in China for centuries..

Reishi · 2017 · Review Article · Aging and disease

Emerging Roles of Ganoderma Lucidum in Anti-Aging.

Ganoderma lucidum is a white-rot fungus that has been viewed as a traditional Chinese tonic for promoting health and longevity. It has been revealed that several extractions from Ganoderma lucidum, such as Ethanol extract, aqueous extract, mycelia extract, water soluble extract of the culture medium of Ganoderma….

OncologyEnergy & fatigueSkin & hydration

Reishi · 2026 · Research Article · Clinical, cosmetic and investigational dermatology

A Ganoderma lucidum Extract Improves Mitochondrial Function in Aging Skin and Promotes Wound Healing.

PURPOSE: This study investigates whether Ganoderma lucidum extract (GLE) can enhance mitochondrial function to promote wound healing in aging skin. METHODS: Natural senescent human foreskin fibroblasts (BJ) were treated with varying concentrations of GLE, and safe concentrations were determined using the cell counting….

Snow Fungus · 2026 · Research Article · NPJ science of food

Beyond conventional drying: improving the quality of dried Tremella fuciformis via a heat-integrated pretreatment.

Hot-air drying (HAD) of Tremella fuciformis often results in poor rehydration capacity, yellowing, and long preparation times, which significantly reduce its industrial and consumer value. This study introduces a heat-integrated pretreatment (HIP) as a simple and viable strategy to improve the quality of dried T..

Reishi · 2026 · Research Article · Pharmaceuticals (Basel, Switzerland)

Characterization of a New Biocomposite Based on Bioactive Compounds from Ganoderma lucidum and Jellyfish Collagen Destined for In Vitro Evaluation of Antitumor Effects in the Oral Cavity.

Background/Objectives: Oral squamous cell carcinoma (OSCC) remains a major therapeutic challenge due to treatment-related toxicity and impaired oral tissue regeneration..

Maitake · 2026 · Journal Article · Journal of dairy science

Characterization of the gel-binding mechanism of Grifola frondosa polysaccharide and polymerized whey protein by simultaneous rheology and Fourier-transform infrared spectroscopy and its application in yogurt.

The study aimed to develop and characterize composite hydrogels composed of polymerized whey protein (PWP, 10% wt/vol) and Grifola frondosa polysaccharide (GFP, 0%-4% wt/vol) as a natural functional additive for yogurt..

Energy & fatigueSkin & hydration

Turkey Tail · 2026 · Research Article · ACS omega

Development and Application of a Hybrid Support of Laccase from Trametes versicolor with Zinc Oxide Nanoparticles for Textile Dye Degradation.

A hybrid support based on sodium alginate and green-synthesized ZnO nanoparticles was developed for the immobilization of laccase (Trametes versicolor) and applied to textile dye degradation..

Snow Fungus · 2026 · Research Article · Foods (Basel, Switzerland)

Effects of Tremella fuciformis Powder with Varying Particle Sizes on the Gel Properties of Soy Yogurt.

This study aimed to elucidate the mechanisms by which Tremella fuciformis powder (TFP) improves the gel properties of soy yogurt by investigating the effects of TFP particle size on physicochemical properties and rheological behavior, combined with microstructural characterization and intermolecular interaction….

Metabolic healthSkin & hydration

Enoki · 2026 · Research Article · Foods (Basel, Switzerland)

Effects of Various Drying Techniques on the Quality Attributes and Metabolite Profiles of Flammulina velutipes (Fruiting Body) Based on Non-Target Metabolomics.

Flammulina velutipes (Golden Needle Mushroom, F. velutipes) undergoes rapid postharvest deterioration characterized by browning and decay.

Lion's Mane · 2026 · Research Article · International journal of medical sciences

Efficacy of Combined Hericium erinaceus Mycelium and Undenatured Type II Collagen in Reducing Osteoarthritis Progression in a Preclinical Animal Model.

Osteoarthritis (OA) is a condition linked with aging that impacts joints and leads to functional disability. Hericium erinaceus, a large edible mushroom widely consumed in Asian countries, is recognized as a functional food and has been reported as a beneficial supplement for OA management..

Reishi · 2026 · Journal Article · International journal of biological macromolecules

Enhancing wound dressing efficiency: Cellulose nanofiber sponges loaded with Ganoderma lucidum mycelium fractions.

In this study, cellulose nanofiber (CNF)-based sponges incorporating different Ganoderma lucidum biomass fractions were developed and evaluated as bioactive wound dressing materials..

Immune supportEnergy & fatigueLiver supportSkin & hydration

Reishi · 2026 · Journal Article · Molecular pharmaceutics

Ganoderma lucidum-Derived Nanovesicles Attenuate Multiorgan Senescence via Modulation of Oxidative Stress and Inflammation.

Aging is a complex and multifactorial biological process characterized by cellular senescence and is a major risk factor for numerous age-related diseases. Developing safe and effective anti-aging interventions remains a significant challenge..

Snow Fungus · 2026 · Journal Article · Ultrasonics sonochemistry

Impact of ultrasound-assisted enzymatic extraction on the structural and functional properties of Tremella fuciformis polysaccharide and its application in almond-based milk.

Ultrasound, when combined with enzymatic hydrolysis, distinctly influences the macromolecular structure of Tremella fuciformis polysaccharide, yielding a polysaccharide with improved functional properties..

OncologyImmune supportMetabolic healthSkin & hydration

Reishi · 2026 · Research Article · Molecules (Basel, Switzerland)

In Vitro and In Vivo Evaluation of the Skincare Bioactivity of β-1,3;1,6-Glucans-Rich Ganoderma lucidum Polysaccharides.

Extracted from Ganoderma lucidum mycelium, the developed β-1,3;1,6-glucan rich polysaccharides have the potential to be used during the industrial production of health food products due to their inhibition of metabolic syndrome, immunomodulatory and antitumor activities and other health benefits..

Reishi · 2026 · Research Article · Foods (Basel, Switzerland)

Preparation and In Vitro Bioactivity Evaluation of Ganoderma lucidum Melanin-Stabilized Selenium Nanoparticles.

Selenium nanoparticles (SeNPs), a highly promising candidate as a nutrient fortificant and food additive, face challenges in stability and biosafety. These limitations hinder their application in the food industry.

Gut & microbiomeSkin & hydration

Maitake · 2026 · Research Article · Gels (Basel, Switzerland)

Structural, Interfacial, Gelling, and Digestive Properties of Protein from Grifola frondosa Fruiting Body.

Culture medium formulation influences mushroom yield and composition, but its effect on the properties of edible fungal protein remains unclear. To explore the functional and nutritional properties of proteins from Grifola frondosa (GF) fruiting bodies, the study examined the structural, interfacial, gelling, and….

Oyster Mushroom · 2026 · Journal Article · Meat science

The improving effect of Pleurotus ostreatus polysaccharide-EGCG active preservative films on the functional properties of myofibrillar proteins in refrigerated pork.

This study aimed to investigate the effects of chitosan (CS) /collagen (Clg) films loaded with Pleurotus ostreatus polysaccharide-EGCG conjugates (POP-EGCG) and ε-Polylysine (ε-PL, PL) on the functional properties of myofibrillar proteins (MPs) in refrigerated pork..

Oyster Mushroom · 2026 · Research Article · Journal of fungi (Basel, Switzerland)

The Interference of Mnsod3 Enhances the Tolerance of Pleurotus ostreatus Mycelia to Abiotic Stress by Reshaping the Cell Wall.

In recent years, the response mechanism of Pleurotus ostreatus to abiotic stress has received widespread attention. MnSOD is an important antioxidant enzyme that has been widely studied in animals and plants because of its functions..

Shiitake · 2026 · Research Article · Frontiers in fungal biology

Transcriptomic insights into common defense mechanisms of Pleurotus ostreatus, Agaricus bisporus, and Lentinula edodes against Pseudomonas tolaasii-induced browning.

This study investigated gene expression patterns associated with the browning of mushroom fruiting bodies caused by Pseudomonas tolaasii infection. To address this, Pleurotus ostreatus, Agaricus bisporus, and Lentinula edodes were inoculated with P..

OncologyImmune supportEnergy & fatigueSkin & hydration

Reishi · 2025 · Research Article · Microbial cell factories

ATP deficiency triggers ganoderic acids accumulation via fatty acid β-oxidation pathway in Ganoderma lucidum.

BACKGROUND: Ganoderic acids (GAs), recognized as significant triterpenoid bioactive components in Ganoderma lucidum, exhibit a broad spectrum of pharmacological activities, including immunomodulation, anti-cancer, and anti-aging properties..

Reishi · 2025 · Journal Article · Phytochemistry

Baoslingzhines Q-X: Structurally previously undescribed trace phenolic meroterpenoids from Ganoderma lucidum and their biological activities toward renal fibrosis and cytotoxicity.

Eight previously undescribed phenolic meroterpenoids baoslingzhines Q-X (1-8) including three enantiomeric (±)-baoslingzhines Q-S (1-3) harboring a 2-methylbenzofuran moiety, two trinormeroterpenoids baoslingzhines T and U (4 and 5) containing a 5-methylbenzyl motif as a connection point with another ring, an alkaloid….

OncologySkin & hydration

Oyster Mushroom · 2025 · Journal Article · International journal of biological macromolecules

Chitosan/collagen films loaded with Pleurotus ostreatus polysaccharide-epigallocatechin gallate conjugates with excellent antioxidant and antibacterial activities for pork preservation.

The purpose of this study was to develop a multifunctional active food packaging composite films to solve the environmental and health problems of traditional petroleum-based plastic packaging and for food preservation..