MycoData

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

Oyster Mushroom · 2021 · Journal Article · British poultry science

Agaricus subrufescens and Pleurotus ostreatus mushrooms as alternative additives to antibiotics in diets for broilers challenged with Eimeria spp.

1. The effect of A.

OncologyImmune supportMetabolic healthLiver support

Reishi · 2021 · Journal Article · Mushroom Science and Biotechnology

Cultivation of Ganoderma lucidum and G. sinense on medium containing bamboo chips

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Mushroom Science and Biotechnology in 2021. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

Oyster Mushroom · 2021 · Journal Article · Mushroom Science and Biotechnology

Effect of addition of accelerator during resin-embedding process on transmission electron microscopic images of Pleurotus ostreatus fruiting bodies

Metadata-grounded summary: This journal article indexes research on Pleurotus ostreatus in Mushroom Science and Biotechnology in 2021. MycoData maps the paper to metabolic health based on its title, species context, article metadata, and study classification..

Oyster Mushroom · 2021 · Research Article · Journal of fungi (Basel, Switzerland)

Effect of Nutritional Factors and Copper on the Regulation of Laccase Enzyme Production in Pleurotus ostreatus.

This research aimed to establish the relationship between carbon-nitrogen nutritional factors and copper sulfate on laccase activity (LA) by Pleurotus ostreatus. Culture media composition was tested to choose the nitrogen source.

Oyster Mushroom · 2021 · Journal Article · Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan

Effects of disruption of PKAc genes on wood degradation in Pleurotus ostreatus by

Metadata-grounded summary: This journal article indexes research on Pleurotus ostreatus in Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan in 2021. MycoData maps the paper to metabolic health based on its title, species context, article metadata, and study classification..

Oyster Mushroom · 2021 · Journal Article · Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan

Improvement in specimen preparation method using freeze dry for SEM observation on hymenium of Pleurotus ostreatus

Metabolic healthGut & microbiome

Lion's Mane · 2020 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

A novel oligosaccharide isolated from Hericium erinaceus and its protection against LPS-induced Caco-2 cells via the TLR4/NF-κB pathway.

A novel oligosaccharide showed that protection against LPS-induced Caco-2 cells was purified from the mycelium of Hericium erinaceus (HE). WEP-1 is mainly composed of neutral monosaccharides with molecular weight of 4,010 Da and of mannose, glucose, and galactose in a molar ratio of 1.2:16.9:1..

Niu-Chang-Chih · 2020 · Research Support, Non U.S. Gov'T · Journal of natural products

Antcamphorols A-K, Cytotoxic and ROS Scavenging Triterpenoids from Antrodia camphorata.

Antrodia camphorata is a rare and valuable medicinal mushroom. In this work, 11 new triterpenoids, namely, antcamphorols A-K (1-11), together with 10 known triterpenoids, 12-21, were isolated from dish-cultured A.

OncologyMetabolic health

Cordyceps · 2020 · Research Support, Non U.S. Gov'T · Food research international (Ottawa, Ont.)

Comparative metabolic profiling of Ophiocordyceps sinensis and its cultured mycelia using GC-MS.

Ophiocordyceps sinensis, one of the well-known traditional Chinese medicine, has multiple health-promoting effects. It is used as herbal remedy and health food in Asian countries, together with its cultured mycelia used as a substitute of natural O.

Oyster Mushroom · 2020 · Research Support, Non U.S. Gov'T · Scientific reports

Glucose counteracts wood-dependent induction of lignocellulolytic enzyme secretion in monokaryon and dikaryon submerged cultures of the white-rot basidiomycete Pleurotus ostreatus.

The secretome complexity and lignocellulose degrading capacity of Pleurotus ostreatus monokaryons mkPC9 and mkPC15 and mated dikaryon dkN001 were studied in submerged liquid cultures containing wood, glucose, and wood plus glucose as carbon sources..

Immune supportMetabolic healthGut & microbiome

Mesima · 2020 · Research Support, Non U.S. Gov'T · FASEB journal: official publication of the Federation of American Societies for Experimental Biology

Phellinus linteus polysaccharide extract improves insulin resistance by regulating gut microbiota composition.

The hypoglycemic effect of Phellinus linteus polysaccharide extract (PLPE) has been documented in several previous studies, but the functional interactions among PLPE, gut microbiota, and the hypoglycemic effect remain unclear..

Energy & fatigueMetabolic healthGut & microbiome

Shiitake · 2020 · Research Support, Non U.S. Gov'T · Food research international (Ottawa, Ont.)

Structure characterization of soluble dietary fiber fractions from mushroom Lentinula edodes (Berk.) Pegler and the effects on fermentation and human gut microbiota in vitro.

Aimed to evaluate the changes of three soluble dietary fibers from Lentinula edodes by-products (LESDF) with different molecular weights in the digestive system and their effects on large intestinal fermentation, fermentation products and the types of gut microbiota were determined..

OncologyImmune supportEnergy & fatigueMetabolic health

Maitake · 2020 · Research Support, Non U.S. Gov'T · Journal of food biochemistry

The hypoglycemic and renal protective effects of Grifola frondosa polysaccharides in early diabetic nephropathy.

Grifola frondosa is a basidiomycete polypore fungus. Polysaccharides from G.

Maitake · 2019 · Comparative Study · Food & function

A comparative study on the structures of Grifola frondosa polysaccharides obtained by different decolourization methods and their in vitro antioxidant activities.

Decolourization of polysaccharides is one of the crucial procedures that affects their structure, which is closely related to their bioactivity. Here, Grifola frondosa polysaccharide (GFP) was decolourized with H2O2 and AB-8 macroporous resin..

Metabolic healthSkin & hydration

Shiitake · 2019 · Research Support, Non U.S. Gov'T · Genes

Expression Profile of Laccase Gene Family in White-Rot Basidiomycete Lentinula edodes under Different Environmental Stresses.

Laccases belong to ligninolytic enzymes and play important roles in various biological processes of filamentous fungi, including fruiting-body formation and lignin degradation. The process of fruiting-body development in Lentinula edodes is complex and is greatly affected by environmental conditions..

Energy & fatigueMetabolic health

Enoki · 2018 · Comparative Study · Journal of agricultural and food chemistry

A Comparative Proteome Approach Reveals Metabolic Changes Associated with Flammulina velutipes Mycelia in Response to Cold and Light Stress.

In some industrial processes, cold and light stresses are recognized as two important environmental triggers for the transformation of mycelia into fruit-bodies via intermediate primordia in Flammulina velutipes cultivation. To gain insights into the mechanism of regulation of F..

Immune supportCognition & nervesMetabolic health

Almond Mushroom · 2018 · Research Support, Non U.S. Gov'T · Journal of food and drug analysis

Characteristics of fucose-containing polysaccharides from submerged fermentation of Agaricus blazei Murill.

Fucose is one of important residues of recognition pattern for many immune cells. In this study, we characterized bioactive fucose-containing acidic polysaccharides from submerged fermentation of Agaricus blazei Murill..

Immune supportMetabolic healthSkin & hydration

Lion's Mane · 2018 · Comparative Study · Nutrients

Chondroprotective Effects of a Standardized Extract (KBH-JP-040) from Kalopanax pictus, Hericium erinaceus, and Astragalus membranaceus in Experimentally Induced In Vitro and In Vivo Osteoarthritis Models.

The aim of this study was to investigate the chondroprotective effect of a standardized extract (KBH-JP-040) of the Korean traditional herbs Kalopanax pictus Castor-Aralia, Hericium erinaceus (Bull.) Persoon, and Astragalus membranaceus Schischkin on in vivo and in vitro osteoarthritis (OA) models..

Immune supportMetabolic healthGut & microbiome

Chaga · 2018 · Research Support, Non U.S. Gov'T · Food research international (Ottawa, Ont.)

Effects of simulated gastrointestinal digestion in vitro on the chemical properties, antioxidant activity, α-amylase and α-glucosidase inhibitory activity of polysaccharides from Inonotus obliquus.

This study was aimed to investigate the impacts of gastrointestinal digestion in vitro on the physicochemical properties and the biological activities of polysaccharides from Inonotus obliquus (UIOPS-1)..

OncologyImmune supportMetabolic healthLiver support

Turkey Tail · 2018 · Research Support, Non U.S. Gov'T · PloS one

Potential activities and mechanisms of extracellular polysaccharopeptides from fermented Trametes versicolor on regulating glucose homeostasis in insulin-resistant HepG2 cells.

Polysaccharides derived from mushrooms have potential to control blood sugar, reduce insulin resistance and prevent diabetic complications. The intracellular polysaccharopeptides of Trametes versicolor (TV) have been used as immunologic and oncologic adjuvants..

Enoki · 2018 · Research Support, Non U.S. Gov'T · Scientific reports

Structural elucidation of a polysaccharide from Flammulina velutipes and its immunomodulation activities on mouse B lymphocytes.

A novel polysaccharide FVPB2 was purified from fruiting bodies of Flammulina velutipes. Its structure was elucidated by monosaccharide composition and methylation analyses, UV-Visible and FTIR spectroscopy as well as NMR..

Immune supportMetabolic healthLiver support

Lion's Mane · 2017 · Research Support, Non U.S. Gov'T · Scientific reports

Antihyperglycaemic and organic protective effects on pancreas, liver and kidney by polysaccharides from Hericium erinaceus SG-02 in streptozotocin-induced diabetic mice.

The present work was designed to investigate the antihyperglycaemic and protective effects of two Hericium erinaceus intracellular polysaccharide (HIPS) purified fractions (HIPS1 and HIPS2) from mycelia of H. erinaceus SG-02 on pancreas, liver and kidney in streptozotocin (STZ)-induced diabetic mice..

Enoki · 2017 · Comparative Study · Journal of agricultural and food chemistry

Comparative Proteome Reveals Metabolic Changes during the Fruiting Process in Flammulina velutipes.

Understanding the molecular mechanisms regulating the fruiting process in macro-fungi, especially industrially cultivated mushrooms, has long been a goal in mycological research..

Shiitake · 2017 · Comparative Study · Journal of proteomics

Comparative secretomic analysis of lignocellulose degradation by Lentinula edodes grown on microcrystalline cellulose, lignosulfonate and glucose.

UNLABELLED: Lentinula edodes has the potential to degrade woody and nonwoody lignocellulosic biomass. However, the mechanism of lignocellulose degradation by L.

Enoki · 2017 · Comparative Study · Current microbiology

iTRAQ-Based Comparative Proteomics Analysis of the Fruiting Dikaryon and the Non-fruiting Monokaryon of Flammulina velutipes.

Flammulina velutipes is a potentially excellent fungus to study basic mechanisms of basidiomycete mycelium biology. To provide a better understanding of the mechanism of hyphae growth and fruit-body formation, the biological functions of the differentially abundant proteins between the fruiting dikaryon and the….

Turkey Tail · 2017 · Research Support, Non U.S. Gov'T · Scientific reports

Metabolomic differential analysis of interspecific interactions among white rot fungi Trametes versicolor, Dichomitus squalens and Pleurotus ostreatus.

Interspecific fungal antagonism occurred commonly in the interaction zone of different white rot fungi. This competitive interaction could markedly influence the metabolic pathway of intracellular metabolites, which was associated with the fungal morphology change and growth restriction..

Immune supportEnergy & fatigueMetabolic health

Turkey Tail · 2017 · Research Support, Non U.S. Gov'T · Scientific reports

Proteomic analysis reveals large amounts of decomposition enzymes and major metabolic pathways involved in algicidal process of Trametes versicolor F21a.

A recent algicidal mode indicates that fungal mycelia can wrap and eliminate almost all co-cultivated algal cells within a short time span. However, the underlying molecular mechanism is rarely understood..

OncologyImmune supportMetabolic health

Maitake · 2016 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Anti-tumor and immunomodulatory activity of selenium (Se)-polysaccharide from Se-enriched Grifola frondosa.

A polysaccharide termed Se-GP11 was extracted and purified from Se-enriched Grifola frondosa in our previous study. This study investigated the characterization, anti-tumor and immunomodulatory activity of Se-GP11..

Enoki · 2016 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Antioxidative and renoprotective effects of residue polysaccharides from Flammulina velutipes.

Three extractable polysaccharides including Ac-RPS, Al-RPS and En-RPS were extracted from the residue of Flammulina velutipes and their antioxidative and renoprotective effects on STZ-induced mice were investigated..

Snow Fungus · 2016 · Research Support, Non U.S. Gov'T · Journal of microbiology (Seoul, Korea)

Comparing the sugar profiles and primary structures of alkali-extracted water-soluble polysaccharides in cell wall between the yeast and mycelial phases from Tremella fuciformis.

To gain insights into dimorphism, cell wall polysaccharides from Tremella fuciformis strains were obtained from alkali-extracted water-soluble fractions PTF-M38 (from the mycelial form), PTF-Y3 and PTF-Y8 (from the yeast form) of T. fuciformis strains were used to gain some insights into dimorphism study..

Cognition & nervesMetabolic health

Lion's Mane · 2016 · Research Support, Non U.S. Gov'T · Journal of natural products

Erinacine S, a Rare Sesterterpene from the Mycelia of Hericium erinaceus.

A new sesterterpene, erinacine S, and one cyathane diterpene xyloside, erinacine A, were isolated from the ethanol extract of the mycelia of Hericium erinaceus. Their structures were elucidated by spectroscopic and X-ray analysis..

Enoki · 2016 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Purification, characterization and antioxidant activity of polysaccharides from Flammulina velutipes residue.

In this study, we isolated polysaccharides from Flammulina velutipes residue (FVRP) using microwave-assisted extraction and then purified the polysaccharides by column chromatography to yield FVRP-1, FVRP-2 and FVRP-3..

Zhu Ling · 2016 · Research Support, Non U.S. Gov'T · International journal of biological macromolecules

Structure elucidation and antioxidant activity of a novel polysaccharide from Polyporus umbellatus sclerotia.

A novel water-soluble polysaccharide PUP60S2, with a molecular weight of 1.44×10(4)Da, was obtained from the sclerotia of Polyporus umbellatus by hot water extraction, ethanol precipitation, anion-exchange and size-exclusion chromatography. PUP60S2 was a polysaccharide comprised of about 22.3% glucuronic acid..

Lion's Mane · 2016 · Research Support, Non U.S. Gov'T · Carbohydrate polymers

Structure elucidation of a bioactive polysaccharide from fruiting bodies of Hericium erinaceus in different maturation stages.

HPB-3, a heteropolysaccharide, with a mean molecular weight of 1.5×10(4)Da, was obtained from the maturating-stage IV, V and VI fruiting body of Hericium erinaceus, exhibited higher macrophages stimulation activities, was able to upregulate the functional events mediated by activated macrophages, such as production of….

Immune supportMetabolic healthGut & microbiomeLiver support

Shiitake · 2016 · Research Support, Non U.S. Gov'T · Journal of agricultural and food chemistry

Water-Soluble Compounds from Lentinula edodes Influencing the HMG-CoA Reductase Activity and the Expression of Genes Involved in the Cholesterol Metabolism.

A water extract from Lentinula edodes (LWE) showed HMG-CoA reductase inhibitory activity but contained no statins. NMR indicated the presence of water-soluble α- and β-glucans and fucomannogalactans..

Shiitake · 2015 · Journal Article · Journal of agricultural and food chemistry

Analysis and evaluation of tasty components in the pileus and stipe of Lentinula edodes at different growth stages.

Tasty components in Lentinula edodes pileus and stipe at different growth stages were studied. Mannitol, trehalose, arabitol, and glucose were the main soluble polyols and sugars, whereas succinic acid, malic acid, and citric acid were the main organic acids..

Lion's Mane · 2015 · Journal Article · International journal of food science & technology

Development of fermented Hericium erinaceus juice with high content of L‐glutamine and L‐glutamic acid

Fermented plant beverages (FPB) with a high content of desirable principle components are served as functional foods from several years. Hericium erinaceus is famous for its antimicrobial, antioxidant, antihypertensive and antidiabetic nature.

Immune supportEnergy & fatigueMetabolic healthSkin & hydration

Yellow Morel · 2015 · Journal Article · International journal of food properties

Isolation, Purification, and Characterization of Polysaccharides from Wide Morchella esculenta (L.) Pers

A new polysaccharide (MEP-1) was isolated from fruit body of wide Morchella esculenta (L.) Pers with a stepwise procedure of hot water extraction, removal of the protein, dialysis against water, DEAE-Cellulose A52 and Sephadex G-100 columns..

Cognition & nervesMetabolic health

Lion's Mane · 2015 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Protective Effect of Ethanol Extracts of Hericium erinaceus on Alloxan-Induced Diabetic Neuropathic Pain in Rats.

We investigated the effects of Hericium erinaceus (HEE) on alloxan induced diabetic neuropathic pain in laboratory rats. Alloxan induced diabetic rats were administered orally HEE..

OncologyImmune supportEnergy & fatigueMetabolic health

Mesima · 2015 · Journal Article · Journal of investigative medicine: the official publication of the American Federation for Clinical Research

The Effects of Phellinus linteus Polysaccharide Extracts on Cholesterol Efflux in Oxidized Low-Density Lipoprotein-Loaded THP-1 Macrophages.

The removal of excess cellular cholesterol is critical for maintaining cellular cholesterol homeostasis. Phellinus linteus polysaccharide extracts (PLPEs) is an immunomudulatory agent with a molecular weight of 153 kd..

Turkey Tail · 2014 · Research Article · SpringerPlus

Bioconversion of xylose, hexoses and biomass to ethanol by a new isolate of the white rot basidiomycete Trametes versicolor.

Second-generation bioethanol production requires the development of economically feasible and sustainable processes that use renewable lignocellulosic biomass as a starting material..

Cognition & nervesMetabolic health

Lion's Mane · 2014 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Evaluation of the toxicological safety of erinacine A-enriched Hericium erinaceus in a 28-day oral feeding study in Sprague-Dawley rats.

Natural products have attained great importance as they are believed to be the new alternative medicines for conventional therapy. As numerous studies have proved the tremendous medicinal values of Hericium erinaceus, it is necessary to take into account its safety as well as its risk for the recipient..

Immune supportMetabolic healthLiver support

Chaga · 2014 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Protective Effect of Polysaccharides from Inonotus obliquus on Streptozotocin-Induced Diabetic Symptoms and Their Potential Mechanisms in Rats.

The present study aimed to evaluate the therapeutic effects of polysaccharides from Inonotus obliquus (PIO) on streptozotocin- (STZ-) induced diabetic symptoms and their potential mechanisms..

Lion's Mane · 2013 · Journal Article · International journal of biological macromolecules

Evaluation of in vivo antioxidant activity of Hericium erinaceus polysaccharides.

Hericium erinaceus polysaccharide (HEP) is a traditional Chinese medicine. In the present study, chemical composition and antioxidant activity of HEP was investigated..

Metabolic healthLiver support

Yellow Morel · 2013 · Journal Article · Experimental and toxicologic pathology: official journal of the Gesellschaft fur Toxikologische Pathologie

Hepatoprotective activity of cultured mycelium of Morel mushroom, Morchella esculenta.

The hepatoprotective activity of cultured mycelium of morel mushroom Morchella esculenta against CCl(4) and ethanol induced chronic hepatotoxicity was investigated..

OncologyImmune supportMetabolic health

Niu-Chang-Chih · 2013 · Research Article · Evidence-based complementary and alternative medicine: eCAM

Inhibition of Helicobacter pylori CagA-Induced Pathogenesis by Methylantcinate B from Antrodia camphorata.

The bacterial pathogen Helicobacter pylori (Hp) is the leading risk factor for the development of gastric cancer. Hp virulence factor, cytotoxin-associated gene A (CagA) interacted with cholesterol-enriched microdomains and leads to induction of inflammation in gastric epithelial cells (AGS)..

Yellow Morel · 2013 · Journal Article · Industrial crops and products

Optimization of fermentation conditions for crude polysaccharides by Morchella esculenta using soybean curd residue

In this study, orthogonal experimental design and response surface methodology were employed to optimize the fermentation conditions for crude polysaccharides (MPS) production from the strain Morchella esculenta (M. esculenta) by soybean curd residue (SCR)..

Maitake · 2013 · Journal Article · International journal of biological macromolecules

Purification and partial characterization of a novel anti-tumor glycoprotein from cultured mycelia of Grifola frondosa.

A novel glycoprotein GFG-3a with the molecular weight of 88.01kDa and potent anti-tumor activity was isolated from the cultured mycelia of Grifola frondosa GF9801. GFG-3a was heat-sensitive with the decreasing anti-proliferative activity after treated from 56°C to 100°C for 10-120min..

OncologyMetabolic health

Turkey Tail · 2012 · Journal Article · Subtropical Plant Science

Antioxidative activities and chemical characterization of polysaccharide extracts from the widely used mushrooms Ganoderma applanatum, Ganoderma lucidum, Lentinus edodes and Trametes versicolor

Antioxidant activities of polysaccharide extracts of four of the most widely known mushrooms often used in medicinal applications as well as in tea and food, namely Ganoderma applanatum, Ganoderma lucidum, Lentinus edodes and Trametes versicolor, were studied. G.