MycoData

BACKGROUND: Diabetes mellitus is a systemic disease mainly caused by the disorder of metabolism, which has become huge threat to human health. Polysaccharides are the main active substance from Inonotus obliquus (I.

Immune supportMetabolic health

High relevance

Enoki · 2021 · Journal Article · International journal of biological macromolecules

Isolation, characterization and HepG-2 inhibition of a novel proteoglycan from Flammulina velutipes.

Flammulina velutipes has anti-inflammatory, immunomodulatory, antioxidant and many bioactive properties with high contents of carbohydrate, proteins and fibers. In this study, a novel proteoglycan with polysaccharide complexes and protein chain, named PGD1-1, was isolated from F.

OncologyImmune supportMetabolic health

High relevance

Yellow Morel · 2021 · Research Article · Molecules (Basel, Switzerland)

Isolation, Characterization, and Medicinal Potential of Polysaccharides of Morchella esculenta.

Mushroom polysaccharides are active medicinal compounds that possess immune-modulatory and anticancer properties. Currently, the mushroom polysaccharides krestin, lentinan, and polysaccharopeptides are used as anticancer drugs..

OncologyImmune supportCognition & nerves

High relevance

Lion's Mane · 2021 · Journal Article · Food and chemical toxicology: an international journal published for the British Industrial Biological Research Association

Isolation, purification and identification of immunologically active peptides from Hericium erinaceus.

Biologically active peptides released by proteins are important in regulating immunity. The purpose of this study was to isolate and purify an immunologically active peptide from Hericium erinaceus (H.

OncologyImmune support

High relevance

Lion's Mane · 2021 · Research Article · BMC genomics

Key metabolism pathways and regulatory mechanisms of high polysaccharide yielding in Hericium erinaceus.

BACKGROUND: Hericium erinaceus, a rare edible and medicine fungus, is widely used in the food and medical field. Polysaccharides from H.

Immune supportMetabolic health

High relevance

Chaga · 2021 · Research Article · Foods (Basel, Switzerland)

Lipid-Lowering Effects of Inonotus obliquus Polysaccharide In Vivo and In Vitro.

Excessive lipid intake will cause hyperlipidemia, fatty liver metabolism disease, and endanger people's health. Edible fungus polysaccharide is a natural active substance for lipid lowering.

Immune supportMetabolic healthLiver support

High relevance

Reishi · 2021 · Research Article · Frontiers in chemistry

Meroterpenoids From Ganoderma lucidum Mushrooms and Their Biological Roles in Insulin Resistance and Triple-Negative Breast Cancer.

Ganoderma fungi as popular raw materials of numerous functional foods have been extensively investigated. In this study, five pairs of meroterpenoid enantiomers beyond well-known triterpenoids and polysaccharides, dayaolingzhiols I-M (1-5), were characterized from Ganoderma lucidum..

OncologyImmune supportMetabolic health

High relevance

Lion's Mane · 2021 · Journal Article · International journal of biological macromolecules

Multi-walled carbon nanotube polysaccharide modified Hericium erinaceus polysaccharide as an adjuvant to extend immune responses.

In recent years, the utilization of CS-MWCNT as targeted drug carriers has attracted considerable attention. Hericium erinaceus polysaccharide (HEP) has been reported as an immunostimulant to improve immune responses.

Immune supportLiver support

High relevance

Lion's Mane · 2021 · Research Article · Chinese medicine

Neurogenesis-dependent antidepressant-like activity of Hericium erinaceus in an animal model of depression.

BACKGROUND: Depression is a severe neuropsychiatric disorder that affects more than 264 million people worldwide. The efficacy of conventional antidepressants are barely adequate and many have side effects..

Immune supportCognition & nerves

High relevance

Enoki · 2021 · Journal Article · Food & function

Polysaccharide from Flammulina velutipes attenuates markers of metabolic syndrome by modulating the gut microbiota and lipid metabolism in high fat diet-fed mice.

Natural biological macromolecules with putative functions of gut microbiota regulation possess the advantage of improving metabolic syndrome (MS). In this research, we aimed to determine the effects of Flammulina velutipes polysaccharide (FVP) (Expt.

Immune supportMetabolic healthGut & microbiomeLiver support

High relevance

Almond Mushroom · 2021 · Research Article · Insects

Potential of Fumagillin and Agaricus blazei Mushroom Extract to Reduce Nosema ceranae in Honey Bees.

Depending on the infection level and colony strength, Nosema ceranae, a microsporidian endoparasite of the honey bee may have significant consequences on the health, reproduction and productivity of bee colonies. Despite exerting some side effects, fumagillin is most often used for Nosema control..

Immune supportGut & microbiome

High relevance

Shiitake · 2021 · Journal Article · Food & function

Protective effects of sulfated polysaccharides from Lentinula edodes on the lung and liver of MODS mice.

In this work, the effects of sulfated polysaccharides from Lentinula edodes (SPLE) on zymosan (ZYM)-induced multiple organ dysfunction syndrome (MODS) mice were investigated..

Immune supportLiver supportRespiratory

High relevance

Reishi · 2021 · Research Article · Molecules (Basel, Switzerland)

Purification and Characterization of Antibacterial Activity against Phytopathogenic Bacteria in Culture Fluids from Ganoderma lucidum.

Previous studies of Ganoderma lucidum have focused on its medicinal applications. Limited information is available about its antibacterial activity against plant pathogens.

Immune supportGut & microbiome

High relevance

Enoki · 2021 · Journal Article · Food chemistry

Selenium accumulation, speciation, and its effect on nutritive value of Flammulina velutipes (Golden needle mushroom).

Flammulina velutipes is one of the most popular edible mushrooms worldwide. A selenium-biofortification method for its fruiting body was developed using selenite..

Immune support

High relevance

Shiitake · 2021 · Research Article · International journal of molecular sciences

Selenium-Containing Exopolysaccharides Isolated from the Culture Medium of Lentinula edodes: Structure and Biological Activity.

In continuation of our research on the influence of selenium incorporation on the biosynthesis, structure, and immunomodulatory and antioxidant activities of polysaccharides of fungal origin, we have isolated from a post-culture medium of Lentinula edodes a selenium (Se)-containing exopolysaccharide fraction composed….

OncologyImmune supportEnergy & fatigue

High relevance

Wood Ear · 2021 · Research Article · Journal of fungi (Basel, Switzerland)

Skin Wound-Healing Potential of Polysaccharides from Medicinal Mushroom Auricularia auricula-judae (Bull.).

Auricularia auricula-judae, a nutrient-rich mushroom used in traditional medicine, is a macrofungi that exhibits various biological properties. In this study, we have reported on the mechanisms that promote the wound-healing effects of a water-soluble polysaccharide-rich extract obtained from A.

Immune supportMetabolic healthSkin & hydration

High relevance

Lion's Mane · 2021 · Journal Article · International journal of biological macromolecules

Structural characterization of polysaccharide purified from Hericium erinaceus fermented mycelium and its pharmacological basis for application in Alzheimer's disease: Oxidative stress related calcium homeostasis.

The purified polysaccharides from Hericium erinaceus fermented mycelium entitled with PHEB was analyzed and it was mainly composed of six glycosidic bonds. It has been confirmed to show the relieving activity against Alzheimer's Disease (AD)- just as behaviors of B6C3-Tg (APPswePSEN1d E9)/Nju double transgenic….

Immune supportCognition & nerves

High relevance

Lion's Mane · 2021 · Journal Article · Carbohydrate polymers

Surface morphology and protective effect of Hericium erinaceus polysaccharide on cyclophosphamide-induced immunosuppression in mice

The aim of this study was to investigate the surface morphological features and in vivo immunomodulatory activities of a hetero polysaccharide fraction (HEP-W) from Hericium erinaceus..

Immune support

High relevance

Lion's Mane · 2021 · Journal Article · Carbohydrate polymers

Surface morphology and protective effect of Hericium erinaceus polysaccharide on cyclophosphamide-induced immunosuppression in mice.

The aim of this study was to investigate the surface morphological features and in vivo immunomodulatory activities of a hetero polysaccharide fraction (HEP-W) from Hericium erinaceus..

Immune support

High relevance

Enoki · 2021 · Journal Article · International journal of biological macromolecules

The biological regulatory activities of Flammulina velutipes polysaccharide in mice intestinal microbiota, immune repertoire and heart transcriptome.

The effects of a novel Flammulina velutipes polysaccharide (FVP) on intestinal microbiota, immune repertoire and heart transcriptome were investigated in this study. The results showed that FVP treatment could effectively regulate the abundance of colonic microbiota..

Immune supportEnergy & fatigueMetabolic healthGut & microbiome

High relevance

Maitake · 2021 · Journal Article · International journal of biological macromolecules

The effects of quorum sensing molecule farnesol on the yield and activity of extracellular polysaccharide from Grifola frondosa in liquid fermentation.

A strategy by exogenous addition of quorum sensing molecule farnesol to improve the production, antioxidant activity and antitumor activity of extracellular polysaccharide (EPS) of Grifola frondosa by liquid fermentation was proposed in the study..

OncologyImmune supportLiver support

High relevance

Niu-Chang-Chih · 2021 · Journal Article · The American journal of Chinese medicine

The NF- κB Signaling and Wnt/ β-catenin Signaling in MCF-7 Breast Cancer Cells in Response to Bioactive Components from Mushroom Antrodia Camphorata.

Breast cancer is the leading cancer, accounting for approximately 15% cancer deaths in women worldwide. This study investigated the anti-inflammation and anticancer properties of two bioactive components from Antrodia camphorata(AC), a rare medicinal mushroom natively grown in Taiwan and commonly used in Chinese….

OncologyImmune support

High relevance

Snow Fungus · 2021 · Journal Article · International journal of biological macromolecules

Tremella fuciformis polysaccharides ameliorated ulcerative colitis via inhibiting inflammation and enhancing intestinal epithelial barrier function.

The purpose of this paper was to explore the therapeutic effect and underlying mechanism of Tremella fuciformis polysaccharides (TFP) on ulcerative colitis (UC) based on dextran sodium sulfate (DSS)-induced mice UC model and lipopolysaccharide (LPS)-stimulated Caco-2 cells model..

Immune supportMetabolic healthGut & microbiome

High relevance

Lion's Mane · 2021 · Journal Article · Carbohydrate polymers

Value added immunoregulatory polysaccharides of Hericium erinaceus and their effect on the gut microbiota.

Hericium erinaceus polysaccharides (HEPs) were isolated from the fruiting bodies of H. erinaceus with 53.36 % total carbohydrates and 32.56 % uronic acid.

Immune supportGut & microbiome

High relevance

Reishi · 2021 · Research Article · Polymers

WSG, a Glucose-Rich Polysaccharide from Ganoderma lucidum, Combined with Cisplatin Potentiates Inhibition of Lung Cancer In Vitro and In Vivo.

Lung cancer has the highest global mortality rate of any cancer. Although targeted therapeutic drugs are commercially available, the common drug resistance and insensitivity to cisplatin-based chemotherapy, a common clinical treatment for lung cancer, have prompted active research on alternative lung cancer therapies….

OncologyImmune supportMetabolic healthRespiratory

High relevance

Lion's Mane · 2026 · Comparative Study · Natural product research

Unveiling the glucan profile: a comparative study of Lion's Mane and Shiitake mushrooms.

Mushrooms are rich in bioactive polysaccharides, particularly α- and β-glucans, renowned for their immunomodulatory properties. The present study optimised the cultivation methods and quantified α-, β-, and total glucan from Hericium erinaceus (Lion's Mane) and Lentinula edodes (Shiitake) mushrooms..

Immune support

High relevance

Maitake · 2025 · Evaluation Study · Food chemistry

Effects of hydrothermal treatment and low pH on the fermentation characteristics of polysaccharides based water-soluble Maitake with Lactobacillus acidophilus and L. plantarum.

Maitake (Grifola frondosa) is rich in bioactive polysaccharides and is known for its health benefits. This study investigated the effects of hydrothermal treatment (HT) and low pH conditions on Maitake, revealing their effectiveness in the bioactive polysaccharide extraction and metabolite bioavailability..

Immune supportGut & microbiome

High relevance

Lion's Mane · 2024 · Research Support, Non U.S. Gov'T · Amyotrophic lateral sclerosis & frontotemporal degeneration

ALSUntangled #73: Lion's Mane.

Lion's Mane (Hericium erinaceus) has historically been used as traditional medicine in Asia and Europe for its potential benefits in fighting infection and cancer..

OncologyImmune supportCognition & nerves

High relevance

Oyster Mushroom · 2024 · Randomized Controlled Trial · The Journal of nutrition

Consuming Mushrooms When Adopting a Healthy Mediterranean-Style Dietary Pattern Does Not Influence Short-Term Changes of Most Cardiometabolic Disease Risk Factors in Healthy Middle-Aged and Older Adults.

BACKGROUND: Mushrooms are a nutritious food, though knowledge of the effects of mushroom consumption on cardiometabolic risk factors is limited and inconsistent. OBJECTIVE: We assessed the effects of consuming mushrooms as part of a healthy United States Mediterranean-style dietary pattern (MED) on traditional and….

Immune supportMetabolic health

High relevance

Reishi · 2022 · Research Article · Heliyon

Investigating the cellular antioxidant and anti-inflammatory effects of the novel peptides in lingzhi mushrooms.

The lingzhi mushroom (Ganoderma lucidum) is well known for its medicinal properties and has long played a role in traditional oriental medicine due to its health-giving benefits and potential to extend life expectancy..

OncologyImmune supportGut & microbiome

High relevance

Oyster Mushroom · 2022 · Research Article · Frontiers in plant science

Nutritional Characterization and Untargeted Metabolomics of Oyster Mushroom Produced Using Astragalus membranaceus var. mongolicus Stems and Leaves as Substrates.

Astragalus membranaceus var. mongolicus (AMM) is an edible and medicinal material and is commonly used in East Asia.

Immune support

High relevance

Chaga · 2022 · Research Article · Molecules (Basel, Switzerland)

The Anti-Inflammatory Properties of Chaga Extracts Obtained by Different Extraction Methods against LPS-Induced RAW 264.7.

Chaga, a sclerotia formed by the Inonotus obliquus fungus, has been widely recognized for a number of medicinal properties. Although numerous scientific investigations have been published describing various biological activities of chaga from different geographical locations, little work has focused on chaga harvested….

Immune support

High relevance

Chaga · 2021 · Journal Article · Journal of ethnopharmacology

Chaga mushroom extract induces autophagy via the AMPK-mTOR signaling pathway in breast cancer cells.

ETHNOPHARMACOLOGICAL RELEVANCE: Chaga mushrooms (Inonotus obliquus) are commonly used in traditional treatments in Eastern Europe and Asia due to their diverse pharmacological effects, including anti-tumor and immunologic effects..

OncologyImmune support

High relevance

Shiitake · 2020 · Journal Article · Mushroom Science and Biotechnology

Changes in the trehalose content of shiitake (Lentinula edodes) during the drying process

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom Science and Biotechnology in 2020. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

High relevance

Maitake · 2020 · Journal Article · Milk Science

Dietary milk and maitake mushroom (Grifola frondosa) modulate inflammation-related cytokines and apoptosis related-proteins in colon of 1,2-dimethylhydrazine-treated mice

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Milk Science in 2020. MycoData maps the paper to oncology, immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

OncologyImmune supportGut & microbiome

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Maitake · 2020 · Journal Article · Nippon Shokuhin Kagaku Kogaku Kaishi

Effect of Maitake (Grifola frondosa) Mushroom on the Physical Properties and Protein Profile of Cooked Rice

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Nippon Shokuhin Kagaku Kogaku Kaishi in 2020. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

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Cordyceps · 2020 · Research Article · Animals: an open access journal from MDPI

Effect of Spent Mushroom (Cordyceps militaris) on Growth Performance, Immunity, and Intestinal Microflora in Weaning Pigs.

There are limited published reports regarding the optimal dosage of spent mushroom. This study investigated the effect of various levels of spent mushroom derived from C..

OncologyImmune supportEnergy & fatigueMetabolic health

High relevance

Shiitake · 2020 · Journal Article · Mushroom Science and Biotechnology

Reduction of radiocesium in Shiitake (Lentinula edodes) bed logs and fruit bodies by culture with nanoparticle insoluble Prussian blue dispersion liquid and cesiumsorb filter sheet

Immune supportGut & microbiome

High relevance

Cordyceps · 2020 · Journal Article · International journal of biological macromolecules

Structural characterization and immune-enhancing activity of a novel high-molecular-weight polysaccharide from Cordyceps militaris.

A novel homogeneous polysaccharide (CMP-III) was extracted and purified from C. militaris.

Immune supportMetabolic health

High relevance

Shiitake · 2019 · Journal Article · Food Science and Technology Research

Effect of Different Cooking Methods on the True Retention of Vitamins, Minerals, and Bioactive Compounds in Shiitake Mushrooms (Lentinula edodes)

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Food Science and Technology Research in 2019. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

High relevance

Maitake · 2019 · Journal Article · Milk Science

Preventing the formation of aberrant crypt foci in 1,2-dimethylhydrazine-treated mice by dietary milk and maitake mushroom (Grifola frondosa)

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Milk Science in 2019. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

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Maitake · 2018 · Journal Article · Mushroom Science and Biotechnology

Head kidney-derived macrophages activity and survival rate in yellowtail (Seriola quinqueradiata) after oral administration of maitake (Grifola frondosa) fruiting body powder.

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Mushroom Science and Biotechnology in 2018. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

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Shiitake · 2018 · Journal Article · Mushroom Science and Biotechnology

Suppression of Alternaria sooty spot of cabbage by volatile compounds from spent substrates of shiitake (Lentinula edodes) and bunashimeji (Hypsizygus marmoreus)

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom Science and Biotechnology in 2018. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

High relevance

Shiitake · 2017 · Journal Article · Japanese Journal of Applied Entomology and Zoology

Discrimination Methods for Japanese Species of the Genus Morophagoides（Lepidoptera: Tineidae）Injuring Shiitake Mushroom, Lentinula edodes（Agaricales: Tricholomataceae）, Based on the Adults

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Japanese Journal of Applied Entomology and Zoology in 2017. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

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Shiitake · 2017 · Journal Article · The Japanese Forest Society Congress

Relationship between Shiitake (Lentinula edodes) biomass quantified by qPCR assay and decomposition respiration rate

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in The Japanese Forest Society Congress in 2017. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

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Shiitake · 2016 · Journal Article · Japanese Journal of Mycology

Effect of concentrated aqueous saccharide solutions and agar media on the cryopreservation of shiitake (Lentinula edodes) mycelia at −20°C

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Japanese Journal of Mycology in 2016. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

High relevance

Maitake · 2016 · Journal Article · Journal of Cookery Science of Japan

Hydrolysis of Myofibrillar Protein and resultant Tenderization of Beef by Maitake Extract (Grifola frondosa) Injection

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Journal of Cookery Science of Japan in 2016. MycoData maps the paper to immune support based on its title, species context, article metadata, and study classification..

Immune support

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Shiitake · 2016 · Journal Article · Mushroom Science and Biotechnology

Investigation of radiocesium concentration in shiitake (Lentinula edodes) mushroom logs by nondestructive inspection methods. Part 1.

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Mushroom Science and Biotechnology in 2016. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome

High relevance

Shiitake · 2016 · Journal Article · Mushroom Science and Biotechnology

Investigation of radiocesium concentration in shiitake (Lentinula edodes) mushroom logs by nondestructive inspection methods. Part 2.

Immune supportGut & microbiome

High relevance

Shiitake · 2016 · Journal Article · Japanese Journal of Applied Entomology and Zoology

Paragona multisignata (Lepidoptera: Noctuidae) as a New Pest of the Cultivated Shiitake Mushroom, Lentinula edodes

Metadata-grounded summary: This journal article indexes research on Lentinula edodes in Japanese Journal of Applied Entomology and Zoology in 2016. MycoData maps the paper to immune support, gut & microbiome based on its title, species context, article metadata, and study classification..

Immune supportGut & microbiome