MycoData

OncologyImmune supportGut & microbiomeRespiratory

Maitake · 2008 · Journal Article · Biological & pharmaceutical bulletin

Inhibitory effect of MD-Fraction on tumor metastasis: involvement of NK cell activation and suppression of intercellular adhesion molecule (ICAM)-1 expression in lung vascular endothelial cells.

The anti-metastatic activity of MD-Fraction extracted from the maitake mushroom (Grifola frondosa) was examined in an experimental murine model of lung metastasis..

Maitake · 2000 · Patent · journal metadata

SPICED ALCOHOLIC BEVERAGE CONTAINING ANTICANCER SUBSTANCE

A spiced alcoholic beverage containing an anticancer substance and prepared from the active components of i(Inpatiens balsamina) and i(Grifola frondosa); and a medicinal processed food prepared by drying the fruit body of i(Grifola frondosa) immersed in alcohol in the preparation of the spiced alcoholic beverage and….

Niu-Chang-Chih · 2023 · Research Support, Non U.S. Gov'T · Toxicology and applied pharmacology

In vitro and in vivo anti-tumor activity of Coenzyme Q0 against TWIST1-overexpressing HNSCC cells: ROS-mediated inhibition of EMT/metastasis and autophagy/apoptosis induction.

HNSCC (Head and Heck Squamous Cell Carcinoma) is a reasonably prevalent cancer with a high mortality rate. In this study, we tried to examine the anti-metastasis and apoptosis/autophagy actions of Coenzyme Q0 (CoQ0, 2,3-dimethoxy-5-methyl-1,4-benzoquinone), a derivative of Antrodia camphorata in HNCC TWIST1….

Reishi · 2022 · Case Reports · Life (Basel, Switzerland)

Management of Combined Therapy (Ceritinib, A. cinnamomea, G. lucidum, and Photobiomodulation) in Advanced Non-Small-Cell Lung Cancer: A Case Report.

The 5-year survival rate of non-small-cell lung cancer (NSCLC) is still low (<21%) despite recent improvements. Since conventional therapies have a lot of side effects, combined therapy is strongly recommended..

OncologyImmune supportMetabolic healthSkin & hydration

Oyster Mushroom · 2021 · Comparative Study · Anais da Academia Brasileira de Ciencias

Comparison of cell wall polysaccharides in Schizophyllum commune after changing phenotype by mutation.

The Agaricomycetes fungi produce various compounds with pharmaceutical, medicinal, cosmetic, environmental and biotechnological properties. In addition, some polysaccharides extracted from the fungal cell wall have antitumor and immunomodulatory actions..

Shiitake · 2021 · Comparative Study · Surgery today

Nutritional impact of active hexose-correlated compound for patients with resectable or borderline-resectable pancreatic cancer treated with neoadjuvant therapy.

Active hexose-correlated compound (AHCC) is a standardized extract from cultured Lentinula edodes mycelia, used as a potent biological response modifier in cancer treatment. We evaluated the nutritional effect of AHCC, given during neoadjuvant therapy, to patients with pancreatic ductal adenocarcinoma (PDAC)..

OncologyImmune supportMetabolic health

Chaga · 2014 · Research Support, Non U.S. Gov'T · Asian Pacific journal of cancer prevention: APJCP

Inotodiol inhabits proliferation and induces apoptosis through modulating expression of cyclinE, p27, bcl-2, and bax in human cervical cancer HeLa cells.

Inonotus obliquus is a medicinal mushroom that has been used as an effective agent to treat various diseases such as diabetes, tuberculosis and cancer. Inotodiol, an included triterpenoid shows significant anti-tumor effect.

Turkey Tail · 2012 · Patent · journal metadata

DRUG FOR TREATING TUMOR, ANTITUMOR AGENT, METHOD FOR TREATING TUMOR AND KIT FOR TREATING TUMOR

The purpose of the present invention is to provide a drug for treating tumor which is capable of exhibiting a therapeutic effect on non-responders, from among patients with gastric cancer, colorectal cancer and small cell lung cancer, said non-responders showing little response (sensitivity) to an antitumor agent….

Zhu Ling · 2009 · Patent · journal metadata

Chinese medicinal capsule for treating malignant lymphoma

The invention relates to the field of medicament formulation, in particular to a Chinese medicinal capsule for treating malignant lymphoma. Pinellia tuber, tangerine peel, radix ranunculi ternati, self-heal, mustard seed, wall lizard, polyporus umbellatus, fritillaria and oyster are used as raw materials and the raw….

OncologyLiver support

Chaga · 2009 · Research Support, Non U.S. Gov'T · Bulletin of experimental biology and medicine

Cytostatic activity of peptide extracts of medicinal plants on transformed A549, H1299, and HeLa Cells.

Biological activity of peptide extracts of medicinal plants was studied on transformed non-small-cell lung carcinoma A549 cells, lung cancer H1299 cells, and cervical cancer HeLa cells at various cell densities..

Lion's Mane · 2009 · Patent · journal metadata

Edible Hericium coralloides and cultivation method thereof

The invention relates to an edible coralloid Hericium erinaceus and a cultivation method thereof, and belongs to an imitating wild edible fungus and a cultivation method thereof..

OncologyLiver supportRespiratory

Niu-Chang-Chih · 2009 · Patent · journal metadata

New compounds separated from Antrodia camphorate extract

The invention relates to a new compound and the application thereof, in particular to an Antroquinonol B and an Antroquinonol C separated from Antrodia camphorata extract, which can effectively inhibit tumor cell growth..

OncologyImmune supportLiver support

Mesima · 2009 · Patent · journal metadata

Yellow mulberry glossy ganoderma polyoses liquid and preparation method thereof

The present invention relates to polysaccharide solution of phellinus linteus and ganoderma lucidum, and a preparation method thereof, belonging to the technical field of health-care preparation containing raw materials. The polysaccharide solution contains a plurality of types of nutrients..

Mesima · 2008 · Patent · journal metadata

A NOVEL PHELLINUS STRAIN AND THE METHOD FOR ISOLATING beta-1,3 GLUCOMANNAN THEREFROM SHOWING IMMUNE ENHANCING ACTIVITY AND ANTITUMOR ACTIVITY

A beta-1,3 glucomannan polysaccharide isolated from a novel Phellinus strain is provided to increase the immunity and secure the anticancer effect, thereby being used for a pharmaceutical composition or a health functional food for preventing and treating cancers. A novel Phellinus strain has a sequence of SEQ ID: NO..

OncologyImmune supportCognition & nervesEnergy & fatigue

Mesima · 2008 · Patent · journal metadata

ANTIOXIDANT COMPOSITION CONTAINING HISPIDIN DERIVATIVES FROM THE CULTURE BROTH OF FUNGI PHELLINUS AND INONOTUS SPP

A composition containing hispidin derivatives isolated from the culture broth of fungi Phellinus and Inonotus spp. is provided to scavenge superoxide radical, ABTS(2,2'-azinobis-(3-ethylbenzothiazoline-6-sulphonic acid)) radical and DPPH(1,1-Diphenyl-2-Picrylhydrazyl) radical, so that the composition is useful for….

Chaga · 2008 · Patent · journal metadata

Beverage made from edible fungus sporophore

The invention provides edible fungi drink which is made of edible fungi inonotus obliquus and manyzoned polypore and has the advantages of health caring function and eating convenience..

OncologyLiver supportRespiratory

Niu-Chang-Chih · 2008 · Patent · journal metadata

Inhibition of Hepatitis B virus by cyclohexenone compounds from <i

The present invention relates to a compound of Antrodia camphorata used to inhibit HBV, in particular to an extract, 4-hydroxy-2,3-dimethoxy-6-methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone which is isolated from Antrodia camphorata, and its use in inhibiting HBV effectively..

Zhu Ling · 2007 · Patent · journal metadata

Preparation method of detoxification tablet with toad and poria

The invention relates to a method for producing toad Siberian cocklebur toxicide, wherein the excretion of toad adenohypophysis and several components of toad have significant toxicide function and cancer release function..

Shiitake · 2020 · Review · Phytomedicine: international journal of phytotherapy and phytopharmacology

Intrathoracic infusion therapy with Lentinan and chemical irritants for malignant pleural effusion: a systematic review and meta-analysis of 65 randomized controlled trials.

BACKGROUND: Aderivative of Shiitake mushrooms, Lentinan is used to control malignant pleural effusion (MPE) through intrathoracic infusion. PURPOSE: To determine the clinical response, survival and safety of Lentinan plus chemical irritants, and the optimal combinations with chemical irritants, indication, threshold….

OncologyGut & microbiome

OncologyImmune supportLiver support

Zhu Ling · 2020 · Preprint · journal metadata

Polyporus polysaccharide regulates proliferation, apoptosis and migration of bladder cancer cells by polarizing macrophages to M1 subtype in tumor microenvironment

Background: Polyporus polysaccharide (PPS), an active ingredient of traditional Chinese medicinal Polyporus umbellatus, has multiple biological functions, such as anti-cancer, immune-regulating and hepatoprotective activities..

Almond Mushroom · 2020 · Letter · Breastfeeding medicine: the official journal of the Academy of Breastfeeding Medicine

Re: "ABM Clinical Protocol #34: Breast Cancer and Breastfeeding" by Johnson HM, et al.

Metadata-grounded summary: This letter indexes research on Agaricus blazei in Breastfeeding medicine: the official journal of the Academy of Breastfeeding Medicine in 2020. MycoData maps the paper to oncology based on its title, species context, article metadata, and study classification..

OncologyCognition & nervesMetabolic healthGut & microbiome

Shiitake · 2019 · Review · Toxicon: official journal of the International Society on Toxinology

Mushroom poisoning: A proposed new clinical classification.

Mushroom poisoning is a significant and increasing form of toxin-induced-disease. Existing classifications of mushroom poisoning do not include more recently described new syndromes of mushroom poisoning and this can impede the diagnostic process..

Chaga · 2019 · Review · Cancer journal (Sudbury, Mass.)

Practical Application of "About Herbs" Website: Herbs and Dietary Supplement Use in Oncology Settings.

The Integrative Medicine Service at Memorial Sloan Kettering Cancer Center developed and maintains About Herbs (www.aboutherbs.com), which provides summaries of research data including purported uses, adverse effects, and herb-drug interactions for about 284 dietary supplements..

Shiitake · 2018 · Review · Journal of cancer research and clinical oncology

Lentinan as an immunotherapeutic for treating lung cancer: a review of 12 years clinical studies in China.

PURPOSE: Lentinan is a polysaccharide extracted from Shiitake mushrooms that have been used to improve general health for thousands of years in Asia. Lentinan injection is a clinically approved drug in several countries in Asia..

Turkey Tail · 2017 · Review · Frontiers in immunology

Immunomodulatory Properties of Coriolus versicolor: The Role of Polysaccharopeptide.

Traditional uses of herbal medicine have depended mostly on anecdotal evidence for much of history. The increasing application of scientific rigor to the study some of these traditional therapies in recent years has revealed potent bioactivity, notably demonstrated by the 2015 Nobel Prize for the discovery of an….

Mesima · 2015 · Research Article · Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

[Inhibitory effect of mesima reshi UE-1 on biological behavior of human hepatic carcinoma cells in vitro].

Metadata-grounded summary: This research article indexes research on Phellinus linteus in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology in 2015. MycoData maps the paper to oncology, liver support based on its title, species context, article metadata, and study classification..

OncologyLiver support

Oyster Mushroom · 2010 · Journal Article · The Journal of General and Applied Microbiology

Isolation and characterization of a novel ribonuclease from the pink oyster mushroom Pleurotus djamor

A 15-kDa RNase was purified from Pleurotus djamor using ion exchange chromatography and gel filtration. Its N-terminal amino acid sequence was different from previously reported RNase sequences of mushrooms belonging to the genus of Pleurotus and other genera..

OncologyLiver support

Cordyceps · 2010 · Journal Article · Bioscience, Biotechnology, and Biochemistry

Regulatory Mechanisms of Cordyceps sinensis on Steroidogenesis in MA-10 Mouse Leydig Tumor Cells

Cordyceps sinensis (CS) is an herbal medicine that increases steroidogenesis in Leydig cells and improves male reproductive dysfunction. We have found that CS stimulates Leydig cell steroidogenesis through the protein kinase A and protein kinase C signaling pathways..

OncologyEnergy & fatigue

Cordyceps · 2009 · Journal Article · Chemical and Pharmaceutical Bulletin

Apoptosis-Inducing Effects of Sterols from the Dried Powder of Cultured Mycelium of Cordyceps sinensis

The methanolic extract and its ethyl acetate-soluble fraction from the dried powder of cultured Cordyceps sinensis mycelium showed cytotoxic effects on promyelocytic leukemia HL-60 cells..

Maitake · 2009 · Journal Article · Journal of the Society for Integrative Oncology

Maitake.

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Journal of the Society for Integrative Oncology in 2009. MycoData maps the paper to oncology based on its title, species context, article metadata, and study classification..

Cordyceps · 2007 · Journal Article · Chemical and Pharmaceutical Bulletin

New Diphenyl Ethers from the Insect Pathogenic Fungus Cordyceps sp. BCC 1861

Two novel diphenyl ether glycosides and a new diphenyl ether, cordyol A-C (1-3), were isolated from the insect pathogenic fungus Cordyceps sp. BCC 1861.

Cordyceps · 2006 · Journal Article · Journal of Traditional Medicines

Effect of the hot-water extract of Cordyceps sinensis on lung metastasis of B16 melanoma cells

Metadata-grounded summary: This journal article indexes research on Ophiocordyceps sinensis in Journal of Traditional Medicines in 2006. MycoData maps the paper to oncology, respiratory based on its title, species context, article metadata, and study classification..

OncologyImmune supportMetabolic healthLiver support

Reishi · 2006 · Journal Article · Journal of Indian and Buddhist Studies (Indogaku Bukkyogaku Kenkyu)

Lingzhi Yuanzhao's Philosophy of Amitabha's Descent at the Moment of Death

Metadata-grounded summary: This journal article indexes research on Ganoderma lucidum in Journal of Indian and Buddhist Studies (Indogaku Bukkyogaku Kenkyu) in 2006. MycoData maps the paper to oncology, immune support, metabolic health, liver support based on its title, species context, article metadata, and study classification..

Maitake · 2006 · Journal Article · Mycoscience

Low molecular weight maitake MD-Fraction (Klasma-MD) hydrolyzed with endo-β-1,6-glucanase of Trichoderma harzianum induces antitumor activities

Metadata-grounded summary: This journal article indexes research on Grifola frondosa in Mycoscience in 2006. MycoData maps the paper to oncology based on its title, species context, article metadata, and study classification..

OncologyImmune supportGut & microbiome

Maitake · 2004 · Research Support, U.S. Gov'T, P.H.S. · International immunopharmacology

Maitake beta-glucan MD-fraction enhances bone marrow colony formation and reduces doxorubicin toxicity in vitro.

Previous studies have indicated that MD-fraction (MDF), in which the active component is beta 1,6-glucan with beta 1,3-branches, has anti-tumor activity as an oral agent and acts as an immune adjuvant..

OncologyImmune supportEnergy & fatigueRespiratory

Mesima · 2020 · Journal Article · Cell biochemistry and biophysics

Biochemical Properties and Effects on Mitochondrial Respiration of Aqueous Extracts of Basidiomycete Mushrooms.

There are different varieties of mushrooms not yet studied spread all over the planet. The objective of this study was to evaluate biochemical properties and effects on mitochondrial respiration of eight Basidiomycete mushrooms: Flaviporus venustus EF30, Hydnopolyporus fimbriatus EF41 and EF44, Inonotus splitgerberi….

Turkey Tail · 2020 · Research Article · International journal of molecular sciences

Effect of Ferulic Acid, a Phenolic Inducer of Fungal Laccase, on 26S Proteasome Activities In Vitro.

The 26S proteasome is an ATP-dependent protease complex (2.5 MDa) that degrades most cellular proteins in Eukaryotes, typically those modified by a polyubiquitin chain..

Enoki · 2020 · Journal Article · Veterinary immunology and immunopathology

Efficacy of fungal immunomodulatory protein to promote swine immune responses against porcine reproductive and respiratory syndrome virus infection.

Fungal immunomodulatory protein (FIP) is one of the bioactive compounds of edible mushrooms, which has been shown to trigger type 1 T helper (Th1) pathway activation in research with mice..

OncologyImmune supportEnergy & fatigueLiver support

Mesima · 2020 · Journal Article · Life sciences

Elucidating the anti-melanoma effect and mechanisms of Hispolon.

There is a rapid increase in the incidence of melanoma which has led to a global crisis. Thus, there is a great need for developing novel, safe and effective drugs for the treatment of melanoma..

Zhu Ling · 2020 · Journal Article · Complementary therapies in medicine

Long-term use of combined conventional medicine and Chinese herbal medicine decreases the mortality risk of patients with lung cancer.

BACKGROUND: We explored the effect of Chinese herbal medicine (CHM) on the long-term survival of lung cancer patients and hazard ratio (HR) and to analyse CHM herbs and formulas for lung cancer treatment..

Maitake · 2020 · Journal Article · International journal of molecular sciences

Novel Medicinal Mushroom Blend as a Promising Supplement in Integrative Oncology: A Multi-Tiered Study using 4T1 Triple-Negative Mouse Breast Cancer Model.

Although medicinal mushroom extracts have been proposed as promising anti-cancer agents, their precise impacts on metastatic breast cancer are still to be clarified..

OncologyImmune supportMetabolic health

Turkey Tail · 2020 · Journal Article · Inflammation

Oat-Derived β-Glucans Induced Trained Immunity Through Metabolic Reprogramming.

Trained immunity has been recently identified in innate immune cells, which undergo long-term epigenetic and metabolic reprogramming after exposure to pathogens for protection from secondary infections..

OncologyCognition & nervesEnergy & fatigue

Lion's Mane · 2020 · Research Article · Antioxidants (Basel, Switzerland)

Post-Treatment with Erinacine A, a Derived Diterpenoid of H. erinaceus, Attenuates Neurotoxicity in MPTP Model of Parkinson's Disease.

Hericium erinaceus, a valuable pharmaceutical and edible mushroom, contains potent bioactive compounds such as H. erinaceus mycelium (HEM) and its derived ethanol extraction of erinacine A, which have been found to regulate physiological functions in our previous study..

OncologyImmune supportLiver supportRespiratory

Niu-Chang-Chih · 2020 · Research Article · Cancers

The Novel Herbal Cocktail AGA Alleviates Oral Cancer through Inducing Apoptosis, Inhibited Migration and Promotion of Cell Cycle Arrest at SubG1 Phase.

Traditional Chinese medicines Antler's extract (A) and Ganoderma lucidum (G) and Antrodia Camphorata (A) have been known to individually contain a plethora of bioactive factors including triterpenoids, polysaccharides etc., exerting various curative impacts such as anti-inflammatory, anti-oxidative,….

OncologyImmune supportCognition & nervesEnergy & fatigue

Lion's Mane · 2019 · Research Article · Molecules (Basel, Switzerland)

Anti-Inflammatory Effect of Erinacine C on NO Production Through Down-Regulation of NF-κB and Activation of Nrf2-Mediated HO-1 in BV2 Microglial Cells Treated with LPS.

Previous studies have revealed the anti-inflammatory and neuroprotective properties of Hericium erinaceus extracts, including the fact that the active ingredient erinacine C (EC) can induce the synthesis of nerve growth factor..

Lion's Mane · 2019 · Research Article · BMC complementary and alternative medicine

Anti-viral activity of culinary and medicinal mushroom extracts against dengue virus serotype 2: an in-vitro study.

BACKGROUND: Dengue is a mosquito-borne viral infection that has become a major public health concern worldwide. Presently, there is no specific vaccine or treatment available for dengue viral infection..

OncologyImmune supportMetabolic healthLiver support

Niu-Chang-Chih · 2019 · Journal Article · Journal of food biochemistry

Antrodia cinnamomea—An updated minireview of its bioactive components and biological activity

Antrodia cinnamomea or Antrodia camphorata is a distinctive mushroom of Taiwan, which is being used as a traditional medicine to treat various health‐related conditions. More than 78 compounds have been identified in A.

Shiitake · 2019 · Journal Article · Environmental science & technology

Arsenic Concentrations, Speciation, and Localization in 141 Cultivated Market Mushrooms: Implications for Arsenic Exposure to Humans.

Mushrooms accumulate arsenic (As), yet As concentrations, speciation, and localization in cultivated mushrooms across a large geographic distribution are unknown..

Shiitake · 2019 · Journal Article · Integrative cancer therapies

Bioactive Immunomodulatory Compounds: A Novel Combinatorial Strategy for Integrated Medicine in Oncology? BAIC Exposure in Cancer Cells.

The Standardized Cultured Extract of Lentinula edodes Mycelia (also known as Active Hexose Correlated Compound, AHCC) and Wasabia japonica (Wasabi) are natural nutritional supplements known for their immunomodulatory and anticancer potential..