MycoData

Immune supportCognition & nerves

Lion's Mane · 2019 · Research Article · Antioxidants (Basel, Switzerland)

Lion's Mane Mushroom, Hericium erinaceus (Bull.: Fr.) Pers. Suppresses H2O2-Induced Oxidative Damage and LPS-Induced Inflammation in HT22 Hippocampal Neurons and BV2 Microglia.

Oxidative stress and inflammation in neuron-glia system are key factors in the pathogenesis of neurodegenerative diseases. As synthetic drugs may cause side effects, natural products have gained recognition for the prevention or management of diseases..

Oyster Mushroom · 2019 · Journal Article · Journal of agricultural and food chemistry

Mapping the Secretome and Its N-Linked Glycosylation of Pleurotus eryngii and Pleurotus ostreatus Grown on Hemp Stalks.

Our previous research showed that Pleurotus eryngii and Pleurotus ostreatus were effective fungi for pretreatment of industrial hemp stalks to improve enzymatic saccharification..

Gut & microbiomeSkin & hydration

Chaga · 2019 · Research Article · Biomolecules

Melanins of Inonotus Obliquus: Bifidogenic and Antioxidant Properties.

Extracts and melanins from Inonotus obliquus are widely used in medicine due to their high antioxidant properties. This study is dedicated to define the influence of the physicochemical and antioxidant properties of Inonotus obliquus melanins and their bifidogenic effects on Bifidobacterium bifidum 1 and….

Metabolic healthSkin & hydration

Cordyceps · 2019 · Journal Article · Journal of microbiology (Seoul, Korea)

Metabolomic profiling reveals enrichment of cordycepin in senescence process of Cordyceps militaris fruit bodies.

Cordyceps militaris is a species of Cordyceps that is classified in the Cordycipitaceae family and is well known in East Asia as a traditional medicinal mushroom. Its artificial fruit body has been widely cultivated for commercial use in cosmetics, functional food, and medicine..

King Oyster · 2019 · Journal Article · International journal of food science & technology

Microbiological, chemical and sensory aspects of bread supplemented with different percentages of the culinary mushroom Pleurotus eryngii in powder form

Pleurotus eryngii (DC.) Quél. powder was used in bread production.

Cordyceps · 2019 · Research Article · Frontiers in microbiology

milR4 and milR16 Mediated Fruiting Body Development in the Medicinal Fungus Cordyceps militaris.

Cordyceps militaris readily performs sexual reproduction, thus providing a remarkably rich model for understanding the processes involved in sexual development. It could regulate expression of human genes by diet-derived miRNA-like RNAs (milRNAs).

King Oyster · 2019 · Journal Article · Journal of the science of food and agriculture

Modulation of agronomic and nutritional response of Pleurotus eryngii strains by utilizing glycine betaine enriched cotton waste.

BACKGROUND: This study aimed to evaluate the possibility of cotton waste enrichment with glycine betaine (GB) for production of two strains (P9, P10) of king oyster (Pleurotus eryngii)..

OncologyEnergy & fatigueGut & microbiome

Lion's Mane · 2019 · Journal Article · Journal of food biochemistry

Molecular properties, structure, and antioxidant activities of the oligosaccharide Hep‐2 isolated from cultured mycelium of Hericium erinaceus

The oligosaccharide Hep‐2 from cultured mycelium of Hericium erinaceus was obtained with a hollow‐fiber ultrafiltration cartridge and purified with a DEAE Sephadex A‐50 column followed by a Bio‐Gel P‐30 column. The properties, structure, and antioxidant activities of Hep‐2 were studied..

Immune supportMetabolic healthGut & microbiome

Snow Fungus · 2019 · Journal Article · International journal of biological macromolecules

Nanostructures assembly and the property of polysaccharide extracted from Tremella Fuciformis fruiting body.

Polysaccharides from fungi are good free radical scavengers. However, there are no enzymes digesting these polysaccharides in the human body, which limits the use of fungal polysaccharides..

Immune supportCognition & nerves

Cordyceps · 2019 · Research Article · Saudi journal of biological sciences

Neuroprotective and therapeutic effect of Cordyceps militaris on ischemia-induced neuronal death and cognitive impairments.

Cordyceps militaris is a type of fungus consumed by people all over the world and renowned for their nutritional benefits and herbal formulas to promote health and longevity. In the present study investigation was carried out to explore the therapeutic properties and neuroprotective effect of the C..

Reishi · 2019 · Journal Article · International journal of medicinal mushrooms

Optimization of Cultivation Conditions of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes) for the Highest Antioxidant Activity and Antioxidant Content.

Ganoderma lucidum is a famous medicinal mushroom that is rich in antioxidants. The content of antioxidant components of grains can be effectively improved by G.

Cordyceps · 2019 · Research Article · Foods (Basel, Switzerland)

Optimization of Polysaccharide Production from Cordyceps militaris by Solid-State Fermentation on Rice and Its Antioxidant Activities.

Polysaccharides are an important class of bioactive components of medical mushroom and herbs and are now used as natural drugs or dietary supplements on a global scale..

Immune support

Shiitake · 2019 · Journal Article · Innovative Food Science and Emerging Technologies

Optimization of process variables on physical and sensory attributes of shiitake (Lentinula edodes) slices during vacuum frying

As an important research aspect in food industry, fried products possessing both low oil content and good appearance still poses a challenge. The processing parameters of vacuum fried shiitake mushroom slices were investigated using response surface methodology..

Enoki · 2019 · Journal Article · Journal of food processing and preservation

Optimization of semi‐continuous fermentation conditions and preservation of Flammulina velutipes liquid strains

The Flammulina velutipes liquid strains were used as raw material, single factor and orthogonal test were conducted to optimize the semi‐continuous fermentation conditions..

King Oyster · 2019 · Research Article · Frontiers in microbiology

Pleurotus eryngii Genomes Reveal Evolution and Adaptation to the Gobi Desert Environment.

Pleurotus eryngii (King Oyster) is one of the most highly prized edible mushrooms. Among the diverse varieties within P.

Oyster Mushroom · 2019 · Research Article · Molecules (Basel, Switzerland)

Polysaccharides from Basidiocarps of Cultivating Mushroom Pleurotus ostreatus: Isolation and Structural Characterization.

Oyster mushrooms are an interesting source of biologically active glucans and other polysaccharides. This work is devoted to the isolation and structural characterization of polysaccharides from basidiocarps of the cultivated oyster mushroom, Pleurotus ostreatus..

Immune support

Cordyceps · 2019 · Research Article · African health sciences

Polysaccharides obtained from mycelia of Cordyceps militaris attenuated doxorubicin-induced cytotoxic effects in chemotherapy.

OBJECTIVES: Fungus Cordyceps militaris has been used as a herbal tonic in traditional Chinese medicine, which could be surface liquid-cultured for mycelia production. To evaluate the potential of polysaccharides obtained from mycelia of Cordyceps militaris (PS-MCM) for attenuation of side-effects of chemotherapy..

OncologyImmune support

Oyster Mushroom · 2019 · Journal Article · Biological control

Potential for biocontrol of Pleurotus ostreatus green mould disease by Aureobasidium pullulans De Bary (Arnaud)

Pleurotus ostreatus, commonly known as “oyster mushroom”, is an edible fungus economically important worldwide. The green mould, caused by Trichoderma pleuroti and T.

Gut & microbiome

Shiitake · 2019 · Journal Article · Food chemistry

Potential geo-discriminative tools to trace the origins of the dried slices of shiitake (Lentinula edodes) using stable isotope ratios and OPLS-DA.

The Lentinus edodes species, known as shiitake, has a history of extensive use in many cuisines in several East Asian countries owing to its unique and pleasant flavor and texture..

Immune supportMetabolic health

Maitake · 2019 · Journal Article · International journal of biological macromolecules

Preparation of a novel Grifola frondosa polysaccharide-chromium (III) complex and its hypoglycemic and hypolipidemic activities in high fat diet and streptozotocin-induced diabetic mice.

Polysaccharide from Grifola frondosa is one of the best metal-ion chelating agents because of its structural characteristics and excellent functional activities. In this study, we synthesized and characterized a novel Grifola frondosa polysaccharide-chromium (III) [GFP-Cr(III)] complex..

Shiitake · 2019 · Journal Article · Innovative Food Science and Emerging Technologies

Production of a β-d-glucan-rich extract from Shiitake mushrooms (Lentinula edodes) by an extraction/microfiltration/reverse osmosis (nanofiltration) process

A pilot-scale process combining extraction of Shiitake mushroom (Lentinula edodes) powder in water (98 °C, 1 h), cross-flow microfiltration and reverse osmosis (nanofiltration) was performed to obtain β-glucan-rich extracts..

Immune supportCognition & nervesEnergy & fatigue

Cordyceps · 2019 · Research Article · Nutrition research and practice

Protective effect of Cordyceps militaris against hydrogen peroxide-induced oxidative stress in vitro.

BACKGROUND/OBJECTIVES: Excessive production of reactive oxygen species (ROS) such as hydroxyl (·OH), nitric oxide (NO), and hydrogen peroxide (H2O2) is reported to induce oxidative stress. ROS generated by oxidative stress can potentially damage glial cells in the nervous system..

Immune supportCognition & nervesLiver support

Cordyceps · 2019 · Research Article · Food science and biotechnology

Protective role of Cordyceps militaris in Aβ1-42-induced Alzheimer's disease in vivo.

According to the "amyloid cascade hypothesis", amyloid-beta (Aβ) protein occupied one of the risk factors of Alzheimer's disease (AD). Cordyceps militaris (CM) has been reported to exert anti-inflammatory, anti-oxidant, and neuroprotective activities; however, its activity against cognitive dysfunction has not been….

Cordyceps · 2019 · Journal Article · Applied microbiology and biotechnology

Purification and structural characterization of a novel natural pigment: cordycepene from edible and medicinal mushroom Cordyceps militaris.

In the present work, a novel cordycepic pigment was successfully isolated and identified from Cordyceps militaris, as well as named as cordycepene (C14H17N1O4), according to the long unsaturated conjugated polyene structural characteristic..

Skin & hydration

OncologyImmune supportEnergy & fatigueMetabolic health

Zhu Ling · 2019 · Research Article · Molecules (Basel, Switzerland)

Quantitative Analysis of Polysaccharide Composition in Polyporus umbellatus by HPLC-ESI-TOF-MS.

Polyporus umbellatus is a well-known and important medicinal fungus in Asia. Its polysaccharides possess interesting bioactivities such as antitumor, antioxidant, hepatoprotective and immunomodulatory effects..

Cordyceps · 2019 · Journal Article · International journal of medicinal mushrooms

Radical Scavenging and Antiproliferative Effects of Cordycepin-Rich Ethanol Extract from Brown Rice-Cultivated Cordyceps militaris (Ascomycetes) Mycelium on Breast Cancer Cell Lines.

The yield and efficacy of bioactive compounds from Cordyceps militaris fruiting bodies and its fermented grains usually vary with the strain used. In this study, we compared the antiproliferative, apoptotic, and antioxidative properties of ethanolic extracts of fruiting bodies and solid-stated fermented rice (FRE)….

OncologyEnergy & fatigue

Metabolic healthGut & microbiome

King Oyster · 2019 · Journal Article · Journal of microbiology and biotechnology

Ralstonia pickettii Enhance the DDT Biodegradation by Pleurotus eryngii.

DDT is a hydrophobic organic pollutant, which can be bio-accumulated in nature and have adverse consequences on the physical condition of humans and animals. This study investigated the relationship between the white-rot fungus Pleurotus eryngii and biosurfactantproducing bacterium Ralstonia pickettii associated with….

Turkey Tail · 2019 · Journal Article · Environmental technology

Removal of diclofenac from a non-sterile aqueous system using Trametes versicolor with an emphasis on adsorption and biodegradation mechanisms.

This paper describes the search for procedures through which the xenobiotic pollutant diclofenac can be removed from non-sterile aquatic systems. Specifically, adsorption to solid supports (carriers) in combination with biodegradation by non-immobilized and immobilized white rot fungus Trametes versicolor were….

Chaga · 2019 · Research Article · International journal of molecular sciences

RNA-Seq de Novo Assembly and Differential Transcriptome Analysis of Chaga (Inonotus obliquus) Cultured with Different Betulin Sources and the Regulation of Genes Involved in Terpenoid Biosynthesis.

Chaga (Inonotus obliquus) is a medicinal fungus used in traditional medicine of Native American and North Eurasian cultures. Several studies have demonstrated the medicinal properties of chaga's bioactive molecules.

Oncology

Chaga · 2019 · Journal Article · Annals of microbiology

Screening and identification of a Penicillium brevicompactum strain isolated from the fruiting body of Inonotus obliquus and the fermentation production of mycophenolic acid

PURPOSE: Mycophenolic acid (MPA) is a fungal metabolite with a variety of biological activities and widely applied in clinical practices. We herein aimed to isolate a new Penicillium brevicompactum strain from the fruiting body of Inonotus obliquus to improve the production of MPA..

OncologyGut & microbiomeRespiratory

Cordyceps · 2019 · Research Article · OncoTargets and therapy

Se-Enriched Cordyceps militaris Inhibits Cell Proliferation, Induces Cell Apoptosis, And Causes G2/M Phase Arrest In Human Non-Small Cell Lung Cancer Cells.

BACKGROUND: The anticancer effects of cordyceps on various tumors have been reported. However, little is known about the role of selenium (Se)-enriched Cordyceps militaris in non-small cell lung cancer (NSCLC)..

Cordyceps · 2019 · Journal Article · Biological trace element research

Selenium Biofortification and Antioxidant Activity in Cordyceps militaris Supplied with Selenate, Selenite, or Selenomethionine.

Selenium (Se) is an essential trace element with multiple functions that may help mitigate adverse health conditions. Cordyceps militaris is an edible mushroom with medicinal properties..

King Oyster · 2019 · Journal Article · Bioorganic chemistry

Strophasterols E and F: Rearranged ergostane-type sterols from Pleurotus eryngii.

Strophasterols E (1) and F (2) were isolated from the fruiting bodies of Pleurotus eryngii, together with four new ergostane-type sterols (3-6). Single-crystal X-ray diffraction analysis performed on the tris-p-bromobenzoate derivatives of compounds 1 and 2 allowed these two compounds to be identified as the….

Immune supportMetabolic health

Cordyceps · 2019 · Journal Article · International journal of biological macromolecules

Structural characterisation and cholesterol efflux improving capacity of the novel polysaccharides from Cordyceps militaris.

Water extracts of the edible mushroom Cordyceps militaris possess a lipid-lowering effect. However, the types of components and how they exert this effect are not clear.

Cordyceps · 2019 · Research Article · Scientific reports

Study of the whole genome, methylome and transcriptome of Cordyceps militaris.

The complete genome of Cordyceps militaris was sequenced using single-molecule real-time (SMRT) sequencing technology at a coverage over 300×. The genome size was 32.57 Mb, and 14 contigs ranging from 0.35 to 4.58 Mb with an N50 of 2.86 Mb were assembled, including 4 contigs with telomeric sequences on both ends and….

Immune supportCognition & nervesEnergy & fatigue

Niu-Chang-Chih · 2019 · Journal Article · Phytotherapy research: PTR

Study on antrodia camphorata polysaccharide in alleviating the neuroethology of PD mice by decreasing the expression of NLRP3 inflammasome.

Parkinson's disease (PD) is a neurodegenerative disease, and the role of neuroinflammation in the pathogenesis and progression of PD has been confirmed. The polysaccharides and triterpenoids of antrodia camphorata (a polyporous fungus) harbor diverse and powerful pharmacological effects..

Reishi · 2019 · Journal Article · International journal of medicinal mushrooms

Supplementation of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes) Extract Enhanced the Medicinal Values and Prebiotic Index of Hungarian Acacia Honey.

Acacia honey, as a favored delicacy, was supplemented with extracts of distinctive Ganoderma lucidum (lingzhi or reishi) variants to enhance its biological value and lay the foundations for prospective functional food application. Health promoting effects of G..

Gut & microbiome

Chaga · 2019 · Research Article · Mitochondrial DNA. Part B, Resources

The complete mitochondrial genome sequence of the medicinal fungus Inonotus obliquus (Hymenochaetaceae, Basidiomycota).

Inonotus obliquus is a medicinal fungus in the family Hymenochaetaceae and commonly known as chaga. The sclerotium of this fungus has been used as a traditional medicine for long time.

Cordyceps · 2019 · Journal Article · Journal of medicinal food

The Extract of Cordyceps Militaris Inhibited the Proliferation of Cisplatin-Resistant A549 Lung Cancer Cells by Downregulation of H-Ras.

We investigated the antitumor effect of Cordyceps militaris extract (CME) on A549 cisplatin-resistant (CR) lung cancer cells. The proliferation of A549/CR cells was suppressed by CME.

OncologyRespiratory

Energy & fatigueSkin & hydration

King Oyster · 2019 · Journal Article · Food chemistry

The main factors inducing postharvest lignification in king oyster mushrooms (Pleurotus eryngii): Wounding and ROS-mediated senescence.

This study was the first investigation into the main inducers of two lignifications by examining the changes of physicochemical properties and gene expression in king oyster mushrooms, under different conditions, during 21 days of storage..

Immune supportMetabolic healthGut & microbiomeRespiratory

Turkey Tail · 2019 · Research Article · BMC complementary and alternative medicine

The mycelium of the Trametes versicolor (Turkey tail) mushroom and its fermented substrate each show potent and complementary immune activating properties in vitro.

BACKGROUND: The medicinal mushroom Trametes versicolor (Tv, Turkey Tail) is often prepared for consumption as a powder from the fungal mycelium and the fermented substrate on which it grew..

Oyster Mushroom · 2019 · Research Article · Open access Macedonian journal of medical sciences

The Phytochemical Screening, Total Phenolic Contents and Antioxidant Activities in Vitro of White Oyster Mushroom (Pleurotus Ostreatus) Preparations.

BACKGROUND: The popular commercially cultivated Pleurotus ostreatus mushroom contains very high nutrients and bioactive compounds with high antioxidant activity. The ethanolic extract seems to be the most active in preparation..

Mesima · 2019 · Research Article · BMC complementary and alternative medicine

The protective effect of Phellinus linteus decoction on podocyte injury in the kidney of FSGS rats.

BACKGROUND: This study aimed to investigate the effect of the Phellinus linteus (Mesima) decoction on podocyte injury in a rat model of focal and segmental glomerulosclerosis (FSGS) and evaluate the potential mechanisms..

Immune supportSkin & hydration

Lion's Mane · 2019 · Journal Article · International journal of medicinal mushrooms

Therapeutic Effect and Potential Mechanisms of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), Mycelia in Submerged Culture on Ethanol-Induced Chronic Gastric Injury.

Hericium erinaceus (HE) is an edible and medicinal mushroom traditionally used for the treatment of gastric injury in clinical practice. However, scientific evidence of its pharmacological activities has not yet been revealed..

Cognition & nervesMetabolic health

Lion's Mane · 2019 · Journal Article · International journal of medicinal mushrooms

Thirteen-Week Oral Toxicity Evaluation of Erinacine AEnriched Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), Mycelia in Sprague-Dawley Rats.

Recently, erinacine A-enriched Hericium erinaceus (EAHE) mycelia have demonstrated therapeutic efficacy in animal models of neurodegenerative disease, including Alzheimer and Parkinson disease. Despite promising results from animal models, there have been no reports on its toxicity after long-term consumption..

Cordyceps · 2019 · Research Article · ZooKeys

Thitarodes shambalaensis sp. nov. (Lepidoptera, Hepialidae): a new host of the caterpillar fungus Ophiocordyceps sinensis supported by genome-wide SNP data.

A new species of ghost moth, Thitarodes shambalaensis sp. nov., is described from Yanzigou glacier, Mt.

Cordyceps · 2019 · Research Article · Frontiers in microbiology

Transcriptome Analysis of Cordyceps militaris Reveals Genes Associated With Carotenoid Synthesis and Identification of the Function of the Cmtns Gene.

Cordyceps militaris, a valuable edible and medicinal fungus, has attracted increasing attention because of its various bioactive ingredients. However, the biosynthetic pathway of C.

Oyster Mushroom · 2019 · Journal Article · Mycoscience

Variations in 1-octen-3-ol and lipoxygenase gene expression in the oyster mushroom Pleurotus ostreatus according to fruiting body development, tissue specificity, maturity, and postharvest storage

1-Octen-3-ol is considered a major contributor to the characteristic mushroom aroma. It has been proposed that in the oyster mushroom Pleurotus ostreatus, 1-octen-3-ol is synthesized through two pathways comprising either 13-hydroperoxy-9Z,11E-octadecadienoic acid (13-HPOD) or 10-hydroperoxy-8E,12Z-octadecadienoic….